TMEM156

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1antigen processing and presentation of endogenous peptide antigen (GO:0002483)5.56665175
2antigen processing and presentation of endogenous peptide antigen via MHC class I (GO:0019885)5.56665175
3antigen processing and presentation of endogenous antigen (GO:0019883)5.46204236
4positive regulation of gamma-delta T cell activation (GO:0046645)5.32897788
5regulation of B cell receptor signaling pathway (GO:0050855)5.19953055
6DNA deamination (GO:0045006)4.95717907
7positive regulation of antigen receptor-mediated signaling pathway (GO:0050857)4.89966685
8antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G4.69113160
9positive thymic T cell selection (GO:0045059)4.68243417
10negative regulation of phagocytosis (GO:0050765)4.45447790
11negative T cell selection (GO:0043383)4.31024564
12negative thymic T cell selection (GO:0045060)4.28444788
13leukocyte aggregation (GO:0070486)4.13948485
14respiratory burst (GO:0045730)4.12214845
15B cell receptor signaling pathway (GO:0050853)4.08432846
16negative regulation of leukocyte mediated cytotoxicity (GO:0001911)3.91098554
17negative regulation of cell killing (GO:0031342)3.91098554
18Arp2/3 complex-mediated actin nucleation (GO:0034314)3.90138388
19thymic T cell selection (GO:0045061)3.84125562
20positive T cell selection (GO:0043368)3.81120044
21mast cell activation (GO:0045576)3.80978684
22tolerance induction (GO:0002507)3.79631949
23positive regulation of defense response to virus by host (GO:0002230)3.78274485
24regulation of gamma-delta T cell differentiation (GO:0045586)3.78174524
25regulation of B cell differentiation (GO:0045577)3.77188649
26interferon-gamma production (GO:0032609)3.72485799
27regulation of gamma-delta T cell activation (GO:0046643)3.71601534
28T cell migration (GO:0072678)3.69545717
29neutrophil activation involved in immune response (GO:0002283)3.69544674
30positive regulation of B cell differentiation (GO:0045579)3.67254337
31response to pheromone (GO:0019236)3.64092002
32cytidine metabolic process (GO:0046087)3.63860446
33cytidine catabolic process (GO:0006216)3.63860446
34cytidine deamination (GO:0009972)3.63860446
35cellular extravasation (GO:0045123)3.63131761
36regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:00450913.62647201
37immunoglobulin mediated immune response (GO:0016064)3.56933265
38regulation of antigen receptor-mediated signaling pathway (GO:0050854)3.54613536
39negative regulation of mast cell activation (GO:0033004)3.53944621
40neutrophil mediated immunity (GO:0002446)3.50783718
41T cell selection (GO:0045058)3.45920305
42preassembly of GPI anchor in ER membrane (GO:0016254)3.42048196
43neutrophil activation (GO:0042119)3.41894554
44pyrimidine ribonucleoside catabolic process (GO:0046133)3.36715706
45platelet dense granule organization (GO:0060155)3.33766541
46modulation by organism of defense response of other organism involved in symbiotic interaction (GO:03.32272624
47positive regulation by organism of defense response of other organism involved in symbiotic interact3.32272624
48modulation by symbiont of host immune response (GO:0052553)3.32272624
49positive regulation by symbiont of host defense response (GO:0052509)3.32272624
50modulation by symbiont of host defense response (GO:0052031)3.32272624
51modulation by organism of immune response of other organism involved in symbiotic interaction (GO:003.32272624
52behavioral response to nicotine (GO:0035095)3.31626647
53regulation of antigen processing and presentation of peptide antigen (GO:0002583)3.31448005
54T cell costimulation (GO:0031295)3.24777988
55antigen receptor-mediated signaling pathway (GO:0050851)3.21982993
56response to interleukin-15 (GO:0070672)3.21416416
57lymphocyte costimulation (GO:0031294)3.21287178
58regulation of humoral immune response mediated by circulating immunoglobulin (GO:0002923)3.21244994
59cellular response to interleukin-15 (GO:0071350)3.18478058
60NIK/NF-kappaB signaling (GO:0038061)3.18019203
61indolalkylamine metabolic process (GO:0006586)3.17374776
62mast cell degranulation (GO:0043303)3.09273189
63mast cell activation involved in immune response (GO:0002279)3.09273189
64antigen processing and presentation via MHC class Ib (GO:0002475)3.09172715
65granulocyte activation (GO:0036230)3.09041919
66regulation of T cell receptor signaling pathway (GO:0050856)3.07838452
67ribosomal small subunit assembly (GO:0000028)3.07347579
68adenosine metabolic process (GO:0046085)3.06531893
69cellular response to zinc ion (GO:0071294)3.05424515
70B cell mediated immunity (GO:0019724)3.04865957
71detection of light stimulus involved in sensory perception (GO:0050962)3.04200344
72detection of light stimulus involved in visual perception (GO:0050908)3.04200344
73regulation of hypersensitivity (GO:0002883)3.03448095
74rRNA catabolic process (GO:0016075)3.02668257
75regulation of memory T cell differentiation (GO:0043380)3.02580676
76myeloid dendritic cell activation (GO:0001773)3.02294372
77indole-containing compound catabolic process (GO:0042436)3.01459000
78indolalkylamine catabolic process (GO:0046218)3.01459000
79tryptophan catabolic process (GO:0006569)3.01459000
80response to peptidoglycan (GO:0032494)3.00948755
81response to fungus (GO:0009620)3.00461932
82T cell receptor signaling pathway (GO:0050852)2.99556817
83positive regulation of alpha-beta T cell proliferation (GO:0046641)2.99379652
84leukocyte mediated cytotoxicity (GO:0001909)2.97616674
85positive regulation of T cell mediated cytotoxicity (GO:0001916)2.95495127
86pinocytosis (GO:0006907)2.92637719
87sequestering of actin monomers (GO:0042989)2.92495998
88leukocyte degranulation (GO:0043299)2.89274826
89regulation of T cell mediated cytotoxicity (GO:0001914)2.88348465
90regulation of alpha-beta T cell proliferation (GO:0046640)2.87263389
91myeloid cell activation involved in immune response (GO:0002275)2.86873499
92negative regulation of granulocyte differentiation (GO:0030853)2.86785371
93positive regulation of antigen processing and presentation (GO:0002579)2.86480361
94fucose catabolic process (GO:0019317)2.86401230
95L-fucose metabolic process (GO:0042354)2.86401230
96L-fucose catabolic process (GO:0042355)2.86401230
97actin nucleation (GO:0045010)2.86024777
98response to muramyl dipeptide (GO:0032495)2.85687208
99negative regulation of growth of symbiont in host (GO:0044130)2.84232561
100negative regulation of growth of symbiont involved in interaction with host (GO:0044146)2.84232561
101modulation of growth of symbiont involved in interaction with host (GO:0044144)2.84232561
102regulation of growth of symbiont in host (GO:0044126)2.84232561
103negative regulation of interleukin-12 production (GO:0032695)2.83942295
104positive regulation of mast cell activation (GO:0033005)2.83442750
105RNA destabilization (GO:0050779)2.82603893
106regulation of defense response to virus by host (GO:0050691)2.82407008
107cellular response to exogenous dsRNA (GO:0071360)2.81626101
108cellular response to interferon-beta (GO:0035458)2.81216672
109negative regulation of antigen receptor-mediated signaling pathway (GO:0050858)2.80777633
110regulation of mast cell activation (GO:0033003)2.80071215
111RNA phosphodiester bond hydrolysis, exonucleolytic (GO:0090503)2.79893632
112myeloid leukocyte mediated immunity (GO:0002444)2.79458249
113tryptophan metabolic process (GO:0006568)2.77968022
114positive regulation of interleukin-2 biosynthetic process (GO:0045086)2.77911260
115positive regulation of isotype switching (GO:0045830)2.77548110
116defense response to fungus (GO:0050832)2.77055554
117regulation of regulatory T cell differentiation (GO:0045589)2.76494298
118response to protozoan (GO:0001562)2.74594278
119negative regulation of T cell mediated immunity (GO:0002710)2.74495170
120leukocyte cell-cell adhesion (GO:0007159)2.71848296
121interferon-gamma-mediated signaling pathway (GO:0060333)2.71699298
122kynurenine metabolic process (GO:0070189)2.71084709
123L-methionine biosynthetic process from methylthioadenosine (GO:0019509)2.70785202
124regulation of antigen processing and presentation (GO:0002577)2.70070152
125positive regulation of B cell mediated immunity (GO:0002714)2.68474254
126positive regulation of immunoglobulin mediated immune response (GO:0002891)2.68474254
127regulation of interferon-beta biosynthetic process (GO:0045357)2.68377657
128regulation of leukocyte mediated cytotoxicity (GO:0001910)2.68022021
129defense response to protozoan (GO:0042832)2.67253382
130positive regulation of tumor necrosis factor biosynthetic process (GO:0042535)2.66539720
131mature B cell differentiation (GO:0002335)2.64703606
132response to type I interferon (GO:0034340)2.64448634
133positive regulation of leukocyte mediated cytotoxicity (GO:0001912)2.63814625
134dendritic cell chemotaxis (GO:0002407)2.62442842
135positive regulation of lamellipodium assembly (GO:0010592)2.62318503
136activated T cell proliferation (GO:0050798)2.62240041
137piRNA metabolic process (GO:0034587)2.62053259
138natural killer cell activation (GO:0030101)2.61971923
139T cell homeostasis (GO:0043029)2.61191595
140replication fork processing (GO:0031297)2.57566049
141nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291)2.57178295
142axoneme assembly (GO:0035082)2.54979542
143positive regulation of granulocyte differentiation (GO:0030854)2.54922456
144regulation of cell killing (GO:0031341)2.54337833
145RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394)2.51653038
146tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388)2.51653038
147positive regulation of calcium-mediated signaling (GO:0050850)2.49860536
148exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay 2.48465331
149positive regulation of cell killing (GO:0031343)2.47364495
150cell wall macromolecule metabolic process (GO:0044036)2.44408399
151purinergic nucleotide receptor signaling pathway (GO:0035590)2.44072476
152signal peptide processing (GO:0006465)2.44032889
153response to interferon-beta (GO:0035456)2.42758263
154regulation of natural killer cell mediated cytotoxicity (GO:0042269)2.39926698
155regulation of natural killer cell mediated immunity (GO:0002715)2.39926698
156regulation of rhodopsin mediated signaling pathway (GO:0022400)2.36952000
157NADH dehydrogenase complex assembly (GO:0010257)2.34131573
158mitochondrial respiratory chain complex I biogenesis (GO:0097031)2.34131573

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1E2F7_22180533_ChIP-Seq_HELA_Human6.31615188
2FOXP3_17237761_ChIP-ChIP_TREG_Mouse4.65081613
3IRF8_22096565_ChIP-ChIP_GC-B_Human4.26251223
4IRF8_21731497_ChIP-ChIP_J774_Mouse3.87765160
5STAT6_20620947_ChIP-Seq_CD4_POS_T_Human3.73353318
6IRF8_22096565_ChIP-ChIP_GC-B_Mouse3.59488235
7MECOM_23826213_ChIP-Seq_KASUMI_Mouse3.45718774
8SPI1_22096565_ChIP-ChIP_GC-B_Mouse3.14984582
9ZNF274_21170338_ChIP-Seq_K562_Hela3.13703121
10MYB_21317192_ChIP-Seq_ERMYB_Mouse3.03476418
11MYC_22102868_ChIP-Seq_BL_Human2.98679404
12VDR_21846776_ChIP-Seq_THP-1_Human2.76283310
13EGR1_19374776_ChIP-ChIP_THP-1_Human2.73868349
14STAT3_20064451_ChIP-Seq_CD4+T_Mouse2.71423196
15IRF8_27001747_Chip-Seq_BMDM_Mouse2.70642023
16VDR_22108803_ChIP-Seq_LS180_Human2.64709536
17MYB_26560356_Chip-Seq_TH2_Human2.63567592
18STAT4_19710469_ChIP-ChIP_TH1__Mouse2.62503409
19FOXM1_23109430_ChIP-Seq_U2OS_Human2.60762698
20FLI1_27457419_Chip-Seq_LIVER_Mouse2.58848007
21SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse2.58183246
22SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse2.52092864
23IRF1_21803131_ChIP-Seq_MONOCYTES_Human2.50972553
24* SPI1_23547873_ChIP-Seq_NB4_Human2.44253528
25NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse2.44194806
26RUNX1_20887958_ChIP-Seq_HPC-7_Mouse2.41982022
27BP1_19119308_ChIP-ChIP_Hs578T_Human2.41981023
28FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse2.39899786
29SCL_19346495_ChIP-Seq_HPC-7_Human2.33342230
30MYB_26560356_Chip-Seq_TH1_Human2.30021751
31E2F4_17652178_ChIP-ChIP_JURKAT_Human2.26564782
32BRD4_27068464_Chip-Seq_AML-cells_Mouse2.25697485
33MAF_26560356_Chip-Seq_TH1_Human2.24502341
34E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse2.22013752
35EZH2_22144423_ChIP-Seq_EOC_Human2.15999987
36FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse2.10836906
37RUNX1_22412390_ChIP-Seq_EML_Mouse2.09701340
38UTX_26944678_Chip-Seq_JUKART_Human2.07843145
39RUNX_20019798_ChIP-Seq_JUKART_Human2.05070828
40FLI1_20887958_ChIP-Seq_HPC-7_Mouse2.02606511
41ELF1_17652178_ChIP-ChIP_JURKAT_Human2.02115931
42VDR_24763502_ChIP-Seq_THP-1_Human2.00970373
43EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse1.99626095
44ASXL1_24218140_ChIP-Seq_BMDM_Mouse1.97800042
45PCGF2_27294783_Chip-Seq_ESCs_Mouse1.96539935
46IGF1R_20145208_ChIP-Seq_DFB_Human1.95090973
47HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human1.92851894
48NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human1.88208219
49* POU3F2_20337985_ChIP-ChIP_501MEL_Human1.80604374
50TAL1_20887958_ChIP-Seq_HPC-7_Mouse1.73230422
51SFPI1_20887958_ChIP-Seq_HPC-7_Mouse1.70175755
52EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human1.68960838
53MEIS1_20887958_ChIP-Seq_HPC-7_Mouse1.65925065
54IRF1_19129219_ChIP-ChIP_H3396_Human1.65629639
55ER_23166858_ChIP-Seq_MCF-7_Human1.63855635
56E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human1.62758696
57TCF7_22412390_ChIP-Seq_EML_Mouse1.60698914
58ZFP57_27257070_Chip-Seq_ESCs_Mouse1.58824308
59TP53_22573176_ChIP-Seq_HFKS_Human1.58241206
60RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.57752797
61SPI1_23127762_ChIP-Seq_K562_Human1.55450321
62FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human1.54808274
63KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human1.52580219
64MAF_26560356_Chip-Seq_TH2_Human1.51281897
65PCGF2_27294783_Chip-Seq_NPCs_Mouse1.51046556
66CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human1.50562636
67HOXB4_20404135_ChIP-ChIP_EML_Mouse1.50131834
68TAF15_26573619_Chip-Seq_HEK293_Human1.49641816
69GATA3_27048872_Chip-Seq_THYMUS_Human1.49328669
70NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse1.46055533
71GATA2_22383799_ChIP-Seq_G1ME_Mouse1.45417807
72FOXA1_25329375_ChIP-Seq_VCAP_Human1.44962357
73FOXA1_27270436_Chip-Seq_PROSTATE_Human1.44962357
74SUZ12_27294783_Chip-Seq_NPCs_Mouse1.44295967
75LMO2_20887958_ChIP-Seq_HPC-7_Mouse1.42085862
76PU_27001747_Chip-Seq_BMDM_Mouse1.41559848
77GBX2_23144817_ChIP-Seq_PC3_Human1.40792954
78CTBP1_25329375_ChIP-Seq_LNCAP_Human1.40126960
79NFE2_27457419_Chip-Seq_LIVER_Mouse1.39141082
80CTBP2_25329375_ChIP-Seq_LNCAP_Human1.36494939
81GFI1B_20887958_ChIP-Seq_HPC-7_Mouse1.35139593
82BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse1.34319923
83* VDR_23849224_ChIP-Seq_CD4+_Human1.31297552
84EWS_26573619_Chip-Seq_HEK293_Human1.30364918
85ERG_20887958_ChIP-Seq_HPC-7_Mouse1.29865861
86CIITA_25753668_ChIP-Seq_RAJI_Human1.28878492
87FUS_26573619_Chip-Seq_HEK293_Human1.28482009
88P300_19829295_ChIP-Seq_ESCs_Human1.28382156
89PBX1_22567123_ChIP-ChIP_OVCAR3_Human1.28196629
90EGR1_23403033_ChIP-Seq_LIVER_Mouse1.27252135
91* GATA3_21878914_ChIP-Seq_MCF-7_Human1.25554282
92CEBPB_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse1.24660347
93MYC_18940864_ChIP-ChIP_HL60_Human1.24335561
94IRF4_20064451_ChIP-Seq_CD4+T_Mouse1.24247959
95CBP_20019798_ChIP-Seq_JUKART_Human1.24247959
96FOXA1_21572438_ChIP-Seq_LNCaP_Human1.22959680
97NANOG_19829295_ChIP-Seq_ESCs_Human1.22854428
98SOX2_19829295_ChIP-Seq_ESCs_Human1.22854428
99E2F1_21310950_ChIP-Seq_MCF-7_Human1.22454180
100PPARG_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse1.22050472
101MYC_18555785_ChIP-Seq_MESCs_Mouse1.21939487
102EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human1.21352679
103* KDM2B_26808549_Chip-Seq_HPB-ALL_Human1.20881610
104GATA1_22383799_ChIP-Seq_G1ME_Mouse1.20302492
105AR_20517297_ChIP-Seq_VCAP_Human1.20186405
106NOTCH1_21737748_ChIP-Seq_TLL_Human1.19807643
107GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.19365351
108SALL1_21062744_ChIP-ChIP_HESCs_Human1.18944073
109HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse1.18286536
110FOXP3_21729870_ChIP-Seq_TREG_Human1.17866122
111EZH2_27294783_Chip-Seq_NPCs_Mouse1.15847647
112NCOR_22424771_ChIP-Seq_293T_Human1.15442031
113CEBPB_20176806_ChIP-Seq_MACROPHAGES_Mouse1.14931727
114GATA3_26560356_Chip-Seq_TH2_Human1.14692700
115SOX9_22984422_ChIP-ChIP_TESTIS_Rat1.12495629
116GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse1.11392569
117UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human1.09410320
118BCAT_22108803_ChIP-Seq_LS180_Human1.07768934
119TAL1_22897851_ChIP-Seq_JUKARTE6-1_Human1.07709823
120KDM2B_26808549_Chip-Seq_SIL-ALL_Human1.07365077
121GATA3_26560356_Chip-Seq_TH1_Human1.07088746
122PRDM14_20953172_ChIP-Seq_ESCs_Human1.05921453
123SPI1_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse1.05611343
124LYL1_20887958_ChIP-Seq_HPC-7_Mouse1.05384034
125RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human1.04743327
126GABP_17652178_ChIP-ChIP_JURKAT_Human1.04496703
127TAF2_19829295_ChIP-Seq_ESCs_Human1.04298725
128PU.1_20513432_ChIP-Seq_Bcells_Mouse1.03992302
129MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human1.03704006
130Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse1.03321509
131CRX_20693478_ChIP-Seq_RETINA_Mouse1.02813133
132CEBPB_20513432_ChIP-Seq_MACROPHAGES_Mouse1.01997905
133GATA2_20887958_ChIP-Seq_HPC-7_Mouse1.01419769
134EST1_17652178_ChIP-ChIP_JURKAT_Human1.01232850
135TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse0.99177174
136CDX2_21402776_ChIP-Seq_INTESTINAL-VILLUS_Mouse0.99175747
137ELK1_19687146_ChIP-ChIP_HELA_Human0.98730302
138ETS1_20019798_ChIP-Seq_JURKAT_Human0.98661303
139SRF_21415370_ChIP-Seq_HL-1_Mouse0.98626681
140CEBPA_20513432_ChIP-Seq_MACROPHAGES_Mouse0.98352585
141GLI1_17442700_ChIP-ChIP_MESCs_Mouse0.97387386
142NOTCH1_17114293_ChIP-ChIP_T-ALL_Human0.97383357
143EBNA2_21746931_ChIP-Seq_IB4-LCL_Human0.96689079
144AUTS2_25519132_ChIP-Seq_293T-REX_Human0.96668062
145CEBPA_26348894_ChIP-Seq_LIVER_Mouse0.96329691
146ETV2_25802403_ChIP-Seq_MESCs_Mouse0.95951486
147GATA3_22897851_ChIP-Seq_JUKARTE6-1_Human0.95610091
148TAL1_20566737_ChIP-Seq_PRIMARY_FETAL_LIVER_ERYTHROID_Mouse0.94594190
149SMRT_27268052_Chip-Seq_Bcells_Human0.93900618
150PU.1_20513432_ChIP-Seq_MACROPHAGES_Mouse0.93445470
151STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse0.92896836
152OCT4_21477851_ChIP-Seq_ESCs_Mouse0.92780365
153FOXH1_21741376_ChIP-Seq_EPCs_Human0.92317475
154RUNX1_17652178_ChIP-ChIP_JURKAT_Human0.89790108
155VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human0.89407442
156* KDM2B_26808549_Chip-Seq_DND41_Human0.88633778
157MYCN_21190229_ChIP-Seq_SHEP-21N_Human0.88200046
158MYC_18358816_ChIP-ChIP_MESCs_Mouse0.87709234
159FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse0.87308273
160MYC_19030024_ChIP-ChIP_MESCs_Mouse0.84989788
161NFE2L2_22581777_ChIP-Seq_LYMPHOBLASTOID_Human0.84848033
162MYC_19079543_ChIP-ChIP_MESCs_Mouse0.84450694
163TFEB_21752829_ChIP-Seq_HELA_Human0.84410360
164FLI1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.83430287
165XRN2_22483619_ChIP-Seq_HELA_Human0.79088659
166PU.1_20176806_ChIP-Seq_MACROPHAGES_Mouse0.78253551
167GATA1_19941827_ChIP-Seq_MEL_Mouse0.77750922

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0001835_abnormal_antigen_presentation4.48321795
2MP0005671_abnormal_response_to3.35149233
3MP0003303_peritoneal_inflammation3.32956823
4MP0003763_abnormal_thymus_physiology3.14237870
5MP0001800_abnormal_humoral_immune3.10860290
6MP0000685_abnormal_immune_system3.02615301
7MP0003436_decreased_susceptibility_to2.99612745
8MP0002396_abnormal_hematopoietic_system2.95227860
9MP0005000_abnormal_immune_tolerance2.93061559
10MP0001790_abnormal_immune_system2.92770005
11MP0005387_immune_system_phenotype2.92770005
12MP0009785_altered_susceptibility_to2.82923599
13MP0002166_altered_tumor_susceptibility2.80773089
14MP0002452_abnormal_antigen_presenting2.78598353
15MP0005025_abnormal_response_to2.75377906
16MP0002420_abnormal_adaptive_immunity2.74010794
17MP0001819_abnormal_immune_cell2.71851665
18MP0002723_abnormal_immune_serum2.69912956
19MP0002419_abnormal_innate_immunity2.63790409
20MP0002398_abnormal_bone_marrow2.54516893
21MP0002148_abnormal_hypersensitivity_rea2.47528475
22MP0000716_abnormal_immune_system2.32137213
23MP0002006_tumorigenesis2.30397116
24MP0009333_abnormal_splenocyte_physiolog2.15270960
25MP0005464_abnormal_platelet_physiology2.14881296
26MP0002405_respiratory_system_inflammati2.13833995
27MP0001986_abnormal_taste_sensitivity2.08849306
28MP0000689_abnormal_spleen_morphology2.08675788
29MP0002722_abnormal_immune_system2.06137133
30MP0003300_gastrointestinal_ulcer2.04682886
31MP0001853_heart_inflammation1.98064014
32MP0010155_abnormal_intestine_physiology1.97726222
33MP0008057_abnormal_DNA_replication1.97528532
34MP0002429_abnormal_blood_cell1.94246300
35MP0004808_abnormal_hematopoietic_stem1.88279996
36MP0008872_abnormal_physiological_respon1.85451470
37MP0001873_stomach_inflammation1.84983671
38MP0000703_abnormal_thymus_morphology1.82970002
39MP0006072_abnormal_retinal_apoptosis1.82018346
40MP0001845_abnormal_inflammatory_respons1.81657337
41MP0006082_CNS_inflammation1.81614332
42MP0008877_abnormal_DNA_methylation1.80634892
43MP0000858_altered_metastatic_potential1.78477777
44MP0003724_increased_susceptibility_to1.75567487
45MP0000490_abnormal_crypts_of1.75238047
46MP0005645_abnormal_hypothalamus_physiol1.74714359
47MP0000465_gastrointestinal_hemorrhage1.74118279
48MP0003866_abnormal_defecation1.67897041
49MP0002138_abnormal_hepatobiliary_system1.64856687
50MP0003693_abnormal_embryo_hatching1.63236309
51MP0010094_abnormal_chromosome_stability1.61309402
52MP0005551_abnormal_eye_electrophysiolog1.60741167
53MP0003195_calcinosis1.58689315
54MP0005397_hematopoietic_system_phenotyp1.57980629
55MP0001545_abnormal_hematopoietic_system1.57980629
56MP0000372_irregular_coat_pigmentation1.56787450
57MP0004947_skin_inflammation1.53729629
58MP0004147_increased_porphyrin_level1.52736754
59MP0002876_abnormal_thyroid_physiology1.49928709
60MP0005084_abnormal_gallbladder_morpholo1.49850883
61MP0003183_abnormal_peptide_metabolism1.45882277
62MP0003111_abnormal_nucleus_morphology1.43284217
63MP0003806_abnormal_nucleotide_metabolis1.42873708
64MP0009278_abnormal_bone_marrow1.42468764
65MP0008995_early_reproductive_senescence1.39814661
66MP0008875_abnormal_xenobiotic_pharmacok1.37482982
67MP0004142_abnormal_muscle_tone1.36597537
68MP0004510_myositis1.36550908
69MP0003252_abnormal_bile_duct1.33967925
70MP0003448_altered_tumor_morphology1.30923628
71MP0005310_abnormal_salivary_gland1.28440427
72MP0003077_abnormal_cell_cycle1.27339838
73MP0002933_joint_inflammation1.25925382
74MP0001533_abnormal_skeleton_physiology1.25265612
75MP0008469_abnormal_protein_level1.25131529
76MP0002102_abnormal_ear_morphology1.24858550
77MP0005174_abnormal_tail_pigmentation1.24648001
78MP0005253_abnormal_eye_physiology1.23707690
79MP0003011_delayed_dark_adaptation1.23367002
80MP0002019_abnormal_tumor_incidence1.22449566
81MP0002277_abnormal_respiratory_mucosa1.19204279
82MP0003172_abnormal_lysosome_physiology1.18822677
83MP0003646_muscle_fatigue1.15605373
84MP0000343_altered_response_to1.13574319
85MP0001851_eye_inflammation1.13359429
86MP0001905_abnormal_dopamine_level1.12976501
87MP0010307_abnormal_tumor_latency1.12770943
88MP0003786_premature_aging1.11490248
89MP0008058_abnormal_DNA_repair1.08138738
90MP0002163_abnormal_gland_morphology1.06762183
91MP0002928_abnormal_bile_duct1.03444704
92MP0001968_abnormal_touch/_nociception1.03222966
93MP0000371_diluted_coat_color1.02181542
94MP0010352_gastrointestinal_tract_polyps0.98984021
95MP0001501_abnormal_sleep_pattern0.98799220
96MP0001919_abnormal_reproductive_system0.97190421
97MP0002837_dystrophic_cardiac_calcinosis0.96400263
98MP0005389_reproductive_system_phenotype0.96028532
99MP0009764_decreased_sensitivity_to0.93335955
100MP0000015_abnormal_ear_pigmentation0.91792994
101MP0005076_abnormal_cell_differentiation0.90345473
102MP0001529_abnormal_vocalization0.90241032
103MP0009745_abnormal_behavioral_response0.90046957
104MP0005058_abnormal_lysosome_morphology0.87728821
105MP0003787_abnormal_imprinting0.87395326
106MP0010386_abnormal_urinary_bladder0.86834984
107MP0006036_abnormal_mitochondrial_physio0.86760970
108MP0008007_abnormal_cellular_replicative0.84507244
109MP0005075_abnormal_melanosome_morpholog0.83944667
110MP0006292_abnormal_olfactory_placode0.83256697
111MP0004957_abnormal_blastocyst_morpholog0.82785822
112MP0001663_abnormal_digestive_system0.82193624
113MP0001764_abnormal_homeostasis0.81686973
114MP0002095_abnormal_skin_pigmentation0.81486593
115MP0002638_abnormal_pupillary_reflex0.80328702
116MP0002735_abnormal_chemical_nociception0.79656692
117MP0004924_abnormal_behavior0.77453577
118MP0005386_behavior/neurological_phenoty0.77453577
119MP0005085_abnormal_gallbladder_physiolo0.76583179
120MP0000427_abnormal_hair_cycle0.75603367
121MP0004885_abnormal_endolymph0.75474335
122MP0002009_preneoplasia0.74430339
123MP0009763_increased_sensitivity_to0.73754226
124MP0002272_abnormal_nervous_system0.69545079
125MP0000313_abnormal_cell_death0.67493664
126MP0002998_abnormal_bone_remodeling0.65791657
127MP0004043_abnormal_pH_regulation0.65154789
128MP0002736_abnormal_nociception_after0.63468991
129MP0008873_increased_physiological_sensi0.63071598
130MP0000249_abnormal_blood_vessel0.61496821
131MP0003191_abnormal_cellular_cholesterol0.60129833
132MP0006054_spinal_hemorrhage0.57493125
133MP0003566_abnormal_cell_adhesion0.54897927
134MP0000569_abnormal_digit_pigmentation0.54767452
135MP0005023_abnormal_wound_healing0.54056238
136MP0004381_abnormal_hair_follicle0.52760049
137MP0002693_abnormal_pancreas_physiology0.52142451
138MP0000350_abnormal_cell_proliferation0.51354195
139MP0005451_abnormal_body_composition0.51344053
140MP0002132_abnormal_respiratory_system0.51039304
141MP0003795_abnormal_bone_structure0.48895392
142MP0005166_decreased_susceptibility_to0.47640971
143MP0003828_pulmonary_edema0.47375702
144MP0005621_abnormal_cell_physiology0.46993733
145MP0000477_abnormal_intestine_morphology0.46484837
146MP0003075_altered_response_to0.44612350
147MP0005410_abnormal_fertilization0.44608604
148MP0002136_abnormal_kidney_physiology0.42823875
149MP0009765_abnormal_xenobiotic_induced0.42644020

Predicted human phenotypes

RankGene SetZ-score
1Eczematoid dermatitis (HP:0000976)5.55648804
2Elevated erythrocyte sedimentation rate (HP:0003565)5.24372814
3Recurrent abscess formation (HP:0002722)5.10368062
4IgM deficiency (HP:0002850)4.94220922
5Myositis (HP:0100614)4.89553093
6Recurrent bacterial skin infections (HP:0005406)4.41935058
7Recurrent fungal infections (HP:0002841)4.33844358
8Recurrent bronchitis (HP:0002837)4.14391991
9Meningitis (HP:0001287)4.13024734
10Obstructive lung disease (HP:0006536)4.03290235
11Chronic obstructive pulmonary disease (HP:0006510)4.03290235
12Recurrent viral infections (HP:0004429)3.95324724
13Chronic otitis media (HP:0000389)3.94373899
14Retrobulbar optic neuritis (HP:0100654)3.92816651
15Optic neuritis (HP:0100653)3.92816651
16Recurrent cutaneous fungal infections (HP:0011370)3.86613743
17Chronic mucocutaneous candidiasis (HP:0002728)3.86613743
18Orchitis (HP:0100796)3.82153217
19Abnormal delayed hypersensitivity skin test (HP:0002963)3.75634612
20Abnormality of B cell number (HP:0010975)3.72875217
21B lymphocytopenia (HP:0010976)3.72875217
22Thrombocytosis (HP:0001894)3.72791221
23Congenital stationary night blindness (HP:0007642)3.64826740
24Cellulitis (HP:0100658)3.59326883
25Agammaglobulinemia (HP:0004432)3.57649861
26Recurrent skin infections (HP:0001581)3.49591557
27Vasculitis (HP:0002633)3.46821702
28Recurrent gram-negative bacterial infections (HP:0005420)3.45529341
29Pancreatic cysts (HP:0001737)3.44808212
30Mediastinal lymphadenopathy (HP:0100721)3.43056516
31Abnormality of T cells (HP:0002843)3.40503778
32Abnormality of T cell physiology (HP:0011840)3.39185082
33Stomatitis (HP:0010280)3.36330511
34Nasal polyposis (HP:0100582)3.31480883
35Panhypogammaglobulinemia (HP:0003139)3.29722154
36Abnormality of T cell number (HP:0011839)3.28714859
37T lymphocytopenia (HP:0005403)3.28411225
38IgG deficiency (HP:0004315)3.27021832
39Thyroiditis (HP:0100646)3.19498258
40Abnormality of cells of the lymphoid lineage (HP:0012140)3.16084393
41Lymphopenia (HP:0001888)3.15815525
42Recurrent sinusitis (HP:0011108)3.05737130
43Molar tooth sign on MRI (HP:0002419)3.01762292
44Abnormality of midbrain morphology (HP:0002418)3.01762292
45Inflammation of the large intestine (HP:0002037)2.99101775
46Type II lissencephaly (HP:0007260)2.98411499
47Eosinophilia (HP:0001880)2.98360113
48Abnormality of the prostate (HP:0008775)2.98028543
49Abnormality of macrophages (HP:0004311)2.95806819
50Pulmonary infiltrates (HP:0002113)2.89436865
51Abnormality of the renal cortex (HP:0011035)2.87989202
52Gastrointestinal inflammation (HP:0004386)2.87554288
53Congenital, generalized hypertrichosis (HP:0004540)2.86108767
54Renal cortical cysts (HP:0000803)2.80550957
55Severe combined immunodeficiency (HP:0004430)2.80124715
56Keratoconjunctivitis sicca (HP:0001097)2.79594105
57Hemoptysis (HP:0002105)2.78439046
58Encephalitis (HP:0002383)2.77962223
59Pancreatic fibrosis (HP:0100732)2.77154513
60Abnormality of the fingertips (HP:0001211)2.76876531
61Leukocytosis (HP:0001974)2.75476190
62Chest pain (HP:0100749)2.72224879
63Granulocytopenia (HP:0001913)2.72013394
64Gingivitis (HP:0000230)2.71659680
65Attenuation of retinal blood vessels (HP:0007843)2.68976869
66Spontaneous hematomas (HP:0007420)2.67918249
67Abnormality of the nasal mucosa (HP:0000433)2.67620773
68Abnormal rod and cone electroretinograms (HP:0008323)2.67323937
69Papilloma (HP:0012740)2.67274219
70Verrucae (HP:0200043)2.67274219
71Osteomyelitis (HP:0002754)2.66068699
72Gastrointestinal infarctions (HP:0005244)2.65441003
73Recurrent pneumonia (HP:0006532)2.63797175
74Abolished electroretinogram (ERG) (HP:0000550)2.63333492
75Combined immunodeficiency (HP:0005387)2.62537129
76Keratoconjunctivitis (HP:0001096)2.60944134
77Pustule (HP:0200039)2.59585254
78Gastrointestinal stroma tumor (HP:0100723)2.59096200
79IgA deficiency (HP:0002720)2.58773899
80Abnormality of eosinophils (HP:0001879)2.57209322
81Colitis (HP:0002583)2.57084408
82True hermaphroditism (HP:0010459)2.56158354
83Absent rod-and cone-mediated responses on ERG (HP:0007688)2.54838330
84Arterial thrombosis (HP:0004420)2.51742048
85Pendular nystagmus (HP:0012043)2.45558025
86Nephronophthisis (HP:0000090)2.43724954
87Bronchitis (HP:0012387)2.43083281
88Recurrent lower respiratory tract infections (HP:0002783)2.42690423
89Abnormality of the pons (HP:0007361)2.38400267
90Petechiae (HP:0000967)2.38058514
91Periodontitis (HP:0000704)2.37010052
92Chronic sinusitis (HP:0011109)2.36891996
93Vacuolated lymphocytes (HP:0001922)2.35863620
94Papilledema (HP:0001085)2.33500721
95Cerebellar dysplasia (HP:0007033)2.33468790
963-Methylglutaconic aciduria (HP:0003535)2.33264119
97Lymphoma (HP:0002665)2.33201092
98Increased IgE level (HP:0003212)2.32762101
99Hypoplasia of the pons (HP:0012110)2.32529202
100Autoimmune hemolytic anemia (HP:0001890)2.30818096
101Interstitial pulmonary disease (HP:0006530)2.30695488
102Sepsis (HP:0100806)2.30432195
103Autoimmune thrombocytopenia (HP:0001973)2.29087729
104Stomach cancer (HP:0012126)2.28680862
105Neutropenia (HP:0001875)2.28484053
106Hypergammaglobulinemia (HP:0010702)2.24387266
107Hypoproteinemia (HP:0003075)2.23008290
108Decreased electroretinogram (ERG) amplitude (HP:0000654)2.17493940
109Skin ulcer (HP:0200042)2.15991675
110Abnormality of the renal medulla (HP:0100957)2.15969573
111Prolonged bleeding time (HP:0003010)2.15596512
112Poikiloderma (HP:0001029)2.11117977
113Increased CSF lactate (HP:0002490)2.11000163
114Emphysema (HP:0002097)2.10904804
115Increased IgM level (HP:0003496)2.10279738
116Mitochondrial inheritance (HP:0001427)2.09401918
117Lissencephaly (HP:0001339)2.08898405
118Amyotrophic lateral sclerosis (HP:0007354)2.08309424
119Abnormality of the pleura (HP:0002103)2.07860878
120Restrictive lung disease (HP:0002091)2.07724761
121Gangrene (HP:0100758)2.07314889
122Pulmonary embolism (HP:0002204)2.07309843
123Recurrent otitis media (HP:0000403)2.06248675
124Constricted visual fields (HP:0001133)2.05840363
125Acute necrotizing encephalopathy (HP:0006965)2.05557067
126Polydipsia (HP:0001959)2.03060856
127Abnormal drinking behavior (HP:0030082)2.03060856
128Inability to walk (HP:0002540)2.02839447
129Increased neuronal autofluorescent lipopigment (HP:0002074)2.02597772
130Chronic diarrhea (HP:0002028)2.01704322
131Urticaria (HP:0001025)2.01431713
132Prostate neoplasm (HP:0100787)1.99943296
133Abnormality of DNA repair (HP:0003254)1.98794101
134Hypoplasia of the thymus (HP:0000778)1.98464347
135Cheilitis (HP:0100825)1.98208960
136Chronic hepatic failure (HP:0100626)1.97657092
137Epistaxis (HP:0000421)1.97378020
138Limb hypertonia (HP:0002509)1.97021736
139Aplasia/Hypoplasia of the uvula (HP:0010293)1.96576452
140Hypothermia (HP:0002045)1.95072346
141Abnormality of the renal collecting system (HP:0004742)1.93635143
142Medial flaring of the eyebrow (HP:0010747)1.93260423
143Severe muscular hypotonia (HP:0006829)1.92608241
144Clubbing of toes (HP:0100760)1.92091096
145Progressive macrocephaly (HP:0004481)1.90697672
146Decreased central vision (HP:0007663)1.89273917
147Acute encephalopathy (HP:0006846)1.88655240
148Bile duct proliferation (HP:0001408)1.85906464
149Abnormal biliary tract physiology (HP:0012439)1.85906464
150Pulmonary fibrosis (HP:0002206)1.84991549
151Duplicated collecting system (HP:0000081)1.80732329
152Abnormal mitochondria in muscle tissue (HP:0008316)1.80271243
153Hypoalbuminemia (HP:0003073)1.80130392
154Abnormal albumin level (HP:0012116)1.80130392
155Hepatic necrosis (HP:0002605)1.79404973
156Hepatocellular necrosis (HP:0001404)1.79313819
157Cystic liver disease (HP:0006706)1.77283895
158Optic disc pallor (HP:0000543)1.76666437
159Progressive microcephaly (HP:0000253)1.76259434
160Abnormality of the ileum (HP:0001549)1.75283949

Predicted kinase interactions (KEA)

RankGene SetZ-score
1MAP4K15.10109172
2FRK3.89822531
3BLK3.43645478
4TXK3.24749414
5IRAK42.81167768
6ZAK2.78265418
7TEC2.75777102
8MAP4K22.66234183
9ADRBK22.54467274
10BTK2.41048260
11ZAP702.33147558
12ITK2.28909884
13MAP3K142.26123626
14GRK62.25049005
15GRK12.21444991
16EEF2K2.20562376
17SYK2.17668796
18NUAK12.16464173
19TYK22.09913785
20PNCK2.03961717
21BMPR1B2.03600277
22EIF2AK32.02960375
23KIT2.02588999
24TAOK31.92254480
25MUSK1.91440528
26STK101.90346031
27TBK11.85559378
28FES1.73095661
29CSF1R1.66904484
30JAK31.64221646
31PKN21.62431406
32IKBKE1.62415663
33BCKDK1.61700067
34HCK1.57165106
35TESK21.55472749
36CSK1.50915848
37LRRK21.44646473
38JAK11.42425849
39LCK1.41845146
40ERN11.37107451
41BMPR21.35904521
42RIPK41.35739525
43CLK11.34134663
44PIM11.31453328
45INSRR1.30645117
46LYN1.30450385
47NME21.28062409
48FGFR41.25925949
49ERBB31.19478374
50CAMKK21.17933834
51IKBKB1.13914870
52CDC71.13227612
53NEK21.10884607
54MAP2K31.09036015
55MAPK131.08437257
56FGFR31.07927344
57IRAK31.06943663
58KDR1.05666669
59MAP3K101.02305129
60PINK11.01193234
61LIMK11.00612188
62EIF2AK11.00438682
63ADRBK10.99842167
64TESK10.99065857
65WNK30.97263514
66FLT30.96459844
67SIK20.93583494
68EPHB10.93049090
69MAP3K120.89588010
70RPS6KA40.84903779
71WNK40.84155800
72STK40.83885306
73CDK120.82444071
74GRK70.81851534
75MAP3K40.79164463
76CDK80.78311137
77TNK20.78089085
78MAP3K130.77472407
79OXSR10.77364944
80PIM20.75114092
81TRPM70.73661047
82CDK40.72576222
83RPS6KB20.70468903
84CHUK0.66999619
85ATR0.65738683
86SCYL20.65387953
87EIF2AK20.65280075
88PRKCQ0.64508250
89JAK20.63217580
90SIK30.60012750
91PLK40.59987814
92RPS6KA60.58940720
93TRIB30.58437351
94CCNB10.58274973
95NLK0.57306875
96CDK60.56946747
97TGFBR10.56905723
98MAP2K70.54959195
99RPS6KL10.54476500
100RPS6KC10.54476500
101VRK20.53442667
102ALK0.52769722
103MARK30.52460011
104PASK0.52429174
105SRPK10.52040839
106HIPK20.51181920
107PTK2B0.50665048
108BRD40.48921839
109MAP2K20.48563394
110GRK50.47833524
111PRKCE0.46690114
112IGF1R0.46563812
113PDK10.46380559
114ACVR1B0.45575817
115VRK10.44321331
116MAPKAPK30.42781564
117RPS6KB10.42725726
118SGK20.41988057
119MAP3K80.41376521
120PRKCI0.41123119
121TRIM280.40853779
122RPS6KA50.40643860
123ABL10.40232732
124MAPK40.39243148
125MAPKAPK20.38885613
126PRKCD0.37157757
127MAPK110.36666953
128AURKB0.36254150
129TLK10.35830139
130MATK0.35009301
131CDK70.33547993
132PIK3CG0.33459686
133MAP2K60.32734256
134PRKCH0.32314942
135TGFBR20.31398933
136MST40.31190498
137TTN0.30740799
138NEK90.30575125
139TSSK60.29627457
140FYN0.29086868
141CAMK10.28766676
142CDK190.27452233
143IRAK10.27241667
144DYRK20.26128838
145MAP2K10.25903686
146PRKCG0.25845571
147PRKCA0.25544213
148TIE10.25384665
149PRKACA0.24870008

Predicted pathways (KEGG)

RankGene SetZ-score
1Primary immunodeficiency_Homo sapiens_hsa053404.54681544
2Intestinal immune network for IgA production_Homo sapiens_hsa046722.65884298
3Leishmaniasis_Homo sapiens_hsa051402.53561477
4Antigen processing and presentation_Homo sapiens_hsa046122.53537335
5DNA replication_Homo sapiens_hsa030302.53485205
6Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046502.51759496
7B cell receptor signaling pathway_Homo sapiens_hsa046622.48918113
8Measles_Homo sapiens_hsa051622.35619806
9NF-kappa B signaling pathway_Homo sapiens_hsa040642.28812362
10Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005632.14583407
11T cell receptor signaling pathway_Homo sapiens_hsa046602.14215830
12Phototransduction_Homo sapiens_hsa047442.11823194
13Osteoclast differentiation_Homo sapiens_hsa043802.09350851
14Inflammatory bowel disease (IBD)_Homo sapiens_hsa053212.06629740
15Hematopoietic cell lineage_Homo sapiens_hsa046401.98831948
16Non-homologous end-joining_Homo sapiens_hsa034501.95056741
17Mismatch repair_Homo sapiens_hsa034301.82118986
18RNA polymerase_Homo sapiens_hsa030201.80308994
19Graft-versus-host disease_Homo sapiens_hsa053321.76906307
20Linoleic acid metabolism_Homo sapiens_hsa005911.73621366
21Base excision repair_Homo sapiens_hsa034101.72146388
22Protein export_Homo sapiens_hsa030601.70406056
23alpha-Linolenic acid metabolism_Homo sapiens_hsa005921.68897499
24Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046661.67670628
25Cytosolic DNA-sensing pathway_Homo sapiens_hsa046231.65584599
26Herpes simplex infection_Homo sapiens_hsa051681.61219907
27Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006031.57595302
28Oxidative phosphorylation_Homo sapiens_hsa001901.56134985
29Ribosome_Homo sapiens_hsa030101.54256043
30Fc epsilon RI signaling pathway_Homo sapiens_hsa046641.52466053
31Allograft rejection_Homo sapiens_hsa053301.52221137
32Rheumatoid arthritis_Homo sapiens_hsa053231.48358385
33Homologous recombination_Homo sapiens_hsa034401.48280221
34RIG-I-like receptor signaling pathway_Homo sapiens_hsa046221.47148545
35NOD-like receptor signaling pathway_Homo sapiens_hsa046211.46329552
36Butirosin and neomycin biosynthesis_Homo sapiens_hsa005241.43548667
37Toll-like receptor signaling pathway_Homo sapiens_hsa046201.40957448
38Asthma_Homo sapiens_hsa053101.39420420
39Jak-STAT signaling pathway_Homo sapiens_hsa046301.36973776
40Chemokine signaling pathway_Homo sapiens_hsa040621.32390946
41Legionellosis_Homo sapiens_hsa051341.31111420
42Parkinsons disease_Homo sapiens_hsa050121.31056477
43Nitrogen metabolism_Homo sapiens_hsa009101.30156708
44Tuberculosis_Homo sapiens_hsa051521.29478039
45Leukocyte transendothelial migration_Homo sapiens_hsa046701.29439849
46Shigellosis_Homo sapiens_hsa051311.29294082
47Influenza A_Homo sapiens_hsa051641.28351819
48Apoptosis_Homo sapiens_hsa042101.28002447
49Caffeine metabolism_Homo sapiens_hsa002321.23787192
50Toxoplasmosis_Homo sapiens_hsa051451.22721344
51Basal transcription factors_Homo sapiens_hsa030221.21643885
52Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005321.21219335
53Viral myocarditis_Homo sapiens_hsa054161.19409267
54Ether lipid metabolism_Homo sapiens_hsa005651.17587126
55Hepatitis B_Homo sapiens_hsa051611.16577899
56Chagas disease (American trypanosomiasis)_Homo sapiens_hsa051421.16228728
57Neuroactive ligand-receptor interaction_Homo sapiens_hsa040801.14655859
58Spliceosome_Homo sapiens_hsa030401.11997721
59Acute myeloid leukemia_Homo sapiens_hsa052211.10953431
60Other glycan degradation_Homo sapiens_hsa005111.09989721
61Staphylococcus aureus infection_Homo sapiens_hsa051501.08243305
62Cell adhesion molecules (CAMs)_Homo sapiens_hsa045141.05795373
63Transcriptional misregulation in cancer_Homo sapiens_hsa052021.05522454
64Epstein-Barr virus infection_Homo sapiens_hsa051691.04234170
65Pertussis_Homo sapiens_hsa051331.04076446
66Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006011.02975171
67Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001301.00812350
68Fanconi anemia pathway_Homo sapiens_hsa034600.99528302
69Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.95951803
70Butanoate metabolism_Homo sapiens_hsa006500.95935960
71Viral carcinogenesis_Homo sapiens_hsa052030.95226230
72Selenocompound metabolism_Homo sapiens_hsa004500.95037830
73Malaria_Homo sapiens_hsa051440.92474725
74Salmonella infection_Homo sapiens_hsa051320.91190847
75Glycosaminoglycan degradation_Homo sapiens_hsa005310.90452929
76Olfactory transduction_Homo sapiens_hsa047400.89759274
77Maturity onset diabetes of the young_Homo sapiens_hsa049500.89674703
78Cytokine-cytokine receptor interaction_Homo sapiens_hsa040600.89525459
79Cell cycle_Homo sapiens_hsa041100.89422847
80p53 signaling pathway_Homo sapiens_hsa041150.89246586
81Nucleotide excision repair_Homo sapiens_hsa034200.86015924
82TNF signaling pathway_Homo sapiens_hsa046680.85286143
83HTLV-I infection_Homo sapiens_hsa051660.85093404
84Pentose phosphate pathway_Homo sapiens_hsa000300.83750762
85Tryptophan metabolism_Homo sapiens_hsa003800.83463042
86Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030080.83084737
87Platelet activation_Homo sapiens_hsa046110.80080312
88Autoimmune thyroid disease_Homo sapiens_hsa053200.79561441
89SNARE interactions in vesicular transport_Homo sapiens_hsa041300.79310197
90Non-small cell lung cancer_Homo sapiens_hsa052230.78774125
91Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049320.78121051
92Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.77754933
93Pancreatic cancer_Homo sapiens_hsa052120.77051021
94Bacterial invasion of epithelial cells_Homo sapiens_hsa051000.76637302
95Regulation of autophagy_Homo sapiens_hsa041400.76472366
96Chronic myeloid leukemia_Homo sapiens_hsa052200.76073580
97Lysosome_Homo sapiens_hsa041420.74278217
98Alzheimers disease_Homo sapiens_hsa050100.74213344
99Taste transduction_Homo sapiens_hsa047420.73157097
100Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.70775018
101Synthesis and degradation of ketone bodies_Homo sapiens_hsa000720.70667741
102Arachidonic acid metabolism_Homo sapiens_hsa005900.70305090
103Hepatitis C_Homo sapiens_hsa051600.69495504
104Purine metabolism_Homo sapiens_hsa002300.66876053
105One carbon pool by folate_Homo sapiens_hsa006700.66063691
106Huntingtons disease_Homo sapiens_hsa050160.63150878
107Steroid hormone biosynthesis_Homo sapiens_hsa001400.62517013
108Neurotrophin signaling pathway_Homo sapiens_hsa047220.62155381
109Proteasome_Homo sapiens_hsa030500.60941114
110Morphine addiction_Homo sapiens_hsa050320.58506514
111RNA degradation_Homo sapiens_hsa030180.58471278
112Systemic lupus erythematosus_Homo sapiens_hsa053220.57073367
113Chemical carcinogenesis_Homo sapiens_hsa052040.56823774
114Phagosome_Homo sapiens_hsa041450.56813468
115RNA transport_Homo sapiens_hsa030130.55196561
116Pyrimidine metabolism_Homo sapiens_hsa002400.53945514
117Peroxisome_Homo sapiens_hsa041460.53757296
118Carbohydrate digestion and absorption_Homo sapiens_hsa049730.53655939
119VEGF signaling pathway_Homo sapiens_hsa043700.53006284
120Taurine and hypotaurine metabolism_Homo sapiens_hsa004300.51388769
121ABC transporters_Homo sapiens_hsa020100.49167059
122Ascorbate and aldarate metabolism_Homo sapiens_hsa000530.48440509
123Primary bile acid biosynthesis_Homo sapiens_hsa001200.48234952
124Small cell lung cancer_Homo sapiens_hsa052220.47945525
125Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.47940067
126N-Glycan biosynthesis_Homo sapiens_hsa005100.47626322
127Drug metabolism - cytochrome P450_Homo sapiens_hsa009820.47042429
128Renin-angiotensin system_Homo sapiens_hsa046140.44880907
129Retinol metabolism_Homo sapiens_hsa008300.43760951
130AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049330.42523647
131Type I diabetes mellitus_Homo sapiens_hsa049400.42285595
132HIF-1 signaling pathway_Homo sapiens_hsa040660.41461563
133Propanoate metabolism_Homo sapiens_hsa006400.39983667
134Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.38897156
135Sphingolipid signaling pathway_Homo sapiens_hsa040710.36841946
136Colorectal cancer_Homo sapiens_hsa052100.36445631
137Inositol phosphate metabolism_Homo sapiens_hsa005620.36099691
138Ovarian steroidogenesis_Homo sapiens_hsa049130.35801073
139Dorso-ventral axis formation_Homo sapiens_hsa043200.35438733
140mRNA surveillance pathway_Homo sapiens_hsa030150.33706652
141Cardiac muscle contraction_Homo sapiens_hsa042600.33279270
142Regulation of actin cytoskeleton_Homo sapiens_hsa048100.32121208
143Valine, leucine and isoleucine degradation_Homo sapiens_hsa002800.31366989
144Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009700.30561214
145MicroRNAs in cancer_Homo sapiens_hsa052060.30480704
146Prolactin signaling pathway_Homo sapiens_hsa049170.30476713
147Lysine degradation_Homo sapiens_hsa003100.28853139
148Phosphatidylinositol signaling system_Homo sapiens_hsa040700.27555247
149Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.26377384
150Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.25998855
151Salivary secretion_Homo sapiens_hsa049700.25566671
152Glycerolipid metabolism_Homo sapiens_hsa005610.24839098
153Sulfur metabolism_Homo sapiens_hsa009200.24454746
154GABAergic synapse_Homo sapiens_hsa047270.23252954
155Nicotine addiction_Homo sapiens_hsa050330.22743802

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