TIFA

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1positive regulation of B cell differentiation (GO:0045579)5.25150801
2antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G5.24058868
3neutrophil activation involved in immune response (GO:0002283)5.22884622
4positive regulation of gamma-delta T cell activation (GO:0046645)5.09819075
5antigen processing and presentation of endogenous peptide antigen via MHC class I (GO:0019885)4.69321314
6antigen processing and presentation of endogenous peptide antigen (GO:0002483)4.69321314
7B cell receptor signaling pathway (GO:0050853)4.54656715
8macrophage activation involved in immune response (GO:0002281)4.53408885
9positive regulation of interleukin-2 biosynthetic process (GO:0045086)4.46036380
10modulation by organism of defense response of other organism involved in symbiotic interaction (GO:04.43669422
11positive regulation by organism of defense response of other organism involved in symbiotic interact4.43669422
12modulation by symbiont of host immune response (GO:0052553)4.43669422
13positive regulation by symbiont of host defense response (GO:0052509)4.43669422
14modulation by symbiont of host defense response (GO:0052031)4.43669422
15modulation by organism of immune response of other organism involved in symbiotic interaction (GO:004.43669422
16antigen processing and presentation of endogenous antigen (GO:0019883)4.31211812
17NIK/NF-kappaB signaling (GO:0038061)4.29977713
18neutrophil activation (GO:0042119)4.11581385
19CD4-positive or CD8-positive, alpha-beta T cell lineage commitment (GO:0043369)4.06878573
20regulation of interferon-beta biosynthetic process (GO:0045357)4.05688633
21immunoglobulin mediated immune response (GO:0016064)4.00700646
22granulocyte activation (GO:0036230)3.97710419
23positive regulation of interferon-alpha production (GO:0032727)3.92242280
24regulation of superoxide anion generation (GO:0032928)3.79541867
25positive regulation of nitric-oxide synthase biosynthetic process (GO:0051770)3.77686362
26regulation of B cell differentiation (GO:0045577)3.72903860
27negative regulation of leukocyte mediated cytotoxicity (GO:0001911)3.72595935
28negative regulation of cell killing (GO:0031342)3.72595935
29regulation of interferon-alpha production (GO:0032647)3.67157339
30regulation of gamma-delta T cell differentiation (GO:0045586)3.65058378
31negative thymic T cell selection (GO:0045060)3.59678599
32positive regulation of humoral immune response (GO:0002922)3.56653313
33B cell homeostasis (GO:0001782)3.53528143
34respiratory burst (GO:0045730)3.52773256
35regulation of alpha-beta T cell proliferation (GO:0046640)3.51601373
36regulation of gamma-delta T cell activation (GO:0046643)3.48403398
37negative T cell selection (GO:0043383)3.47919805
38response to type I interferon (GO:0034340)3.46436242
39regulation of humoral immune response mediated by circulating immunoglobulin (GO:0002923)3.42970264
40positive regulation of mast cell degranulation (GO:0043306)3.42749519
41positive regulation of mast cell activation involved in immune response (GO:0033008)3.42749519
42defense response to protozoan (GO:0042832)3.42314779
43type I interferon signaling pathway (GO:0060337)3.42189464
44cellular response to type I interferon (GO:0071357)3.42189464
45natural killer cell differentiation (GO:0001779)3.36579087
46detection of bacterium (GO:0016045)3.36458728
47detection of other organism (GO:0098543)3.36356305
48myeloid cell activation involved in immune response (GO:0002275)3.34127345
49positive regulation of alpha-beta T cell proliferation (GO:0046641)3.29416084
50regulation of T-helper 1 cell differentiation (GO:0045625)3.29406987
51cellular extravasation (GO:0045123)3.26854277
52B cell proliferation (GO:0042100)3.24522963
53negative regulation of interleukin-12 production (GO:0032695)3.22325703
54response to peptidoglycan (GO:0032494)3.20665959
55regulation of B cell receptor signaling pathway (GO:0050855)3.18663928
56tolerance induction (GO:0002507)3.16379839
57regulation of interleukin-2 biosynthetic process (GO:0045076)3.13745243
58response to host immune response (GO:0052572)3.12026105
59response to immune response of other organism involved in symbiotic interaction (GO:0052564)3.12026105
60macrophage activation (GO:0042116)3.10654007
61positive regulation of B cell mediated immunity (GO:0002714)3.10198013
62positive regulation of immunoglobulin mediated immune response (GO:0002891)3.10198013
63response to interleukin-15 (GO:0070672)3.09590111
64negative regulation of phagocytosis (GO:0050765)3.09398838
65serine transport (GO:0032329)3.07870118
66cellular response to interleukin-15 (GO:0071350)3.07571582
67positive regulation of mast cell activation (GO:0033005)3.07490362
68response to protozoan (GO:0001562)3.05308685
69regulation of dendritic cell antigen processing and presentation (GO:0002604)3.04624944
70T cell lineage commitment (GO:0002360)3.03560759
71positive regulation of myeloid leukocyte mediated immunity (GO:0002888)3.00580253
72response to interferon-alpha (GO:0035455)3.00224342
73positive regulation of isotype switching (GO:0045830)2.99311713
74positive regulation of heterotypic cell-cell adhesion (GO:0034116)2.99208442
75positive regulation of interleukin-8 biosynthetic process (GO:0045416)2.99072000
76myeloid dendritic cell activation (GO:0001773)2.97930964
77interferon-gamma-mediated signaling pathway (GO:0060333)2.97463874
78B cell mediated immunity (GO:0019724)2.97218522
79regulation of CD4-positive, alpha-beta T cell differentiation (GO:0043370)2.96714333
80hepatocyte apoptotic process (GO:0097284)2.96250473
81cellular response to zinc ion (GO:0071294)2.95901539
82regulation of B cell proliferation (GO:0030888)2.95396239
83negative regulation of T cell mediated immunity (GO:0002710)2.94676702
84negative regulation of B cell proliferation (GO:0030889)2.94645128
85response to interferon-beta (GO:0035456)2.93463458
86cellular response to interferon-gamma (GO:0071346)2.92314325
87detection of external biotic stimulus (GO:0098581)2.91452860
88regulation of mast cell degranulation (GO:0043304)2.90486712
89positive regulation of interleukin-2 production (GO:0032743)2.90158377
90detection of molecule of bacterial origin (GO:0032490)2.88850213
91T cell costimulation (GO:0031295)2.88184042
92lipopolysaccharide-mediated signaling pathway (GO:0031663)2.88039626
93cellular response to interferon-beta (GO:0035458)2.87144981
94response to defenses of other organism involved in symbiotic interaction (GO:0052173)2.87131472
95response to host (GO:0075136)2.87131472
96response to host defenses (GO:0052200)2.87131472
97lymphocyte costimulation (GO:0031294)2.84739888
98positive regulation of interferon-beta production (GO:0032728)2.82543356
99positive regulation of B cell activation (GO:0050871)2.81377529
100positive regulation of CD4-positive, alpha-beta T cell differentiation (GO:0043372)2.80841824
101myeloid dendritic cell differentiation (GO:0043011)2.80626740
102myeloid leukocyte activation (GO:0002274)2.80034942
103regulation of antigen processing and presentation of peptide antigen (GO:0002583)2.79983483
104positive regulation of B cell proliferation (GO:0030890)2.79430098
105mast cell activation (GO:0045576)2.79093108
106thymic T cell selection (GO:0045061)2.77794317
107adaptive immune response based on somatic recombination of immune receptors built from immunoglobuli2.77362409
108regulation of antigen processing and presentation (GO:0002577)2.77029113
109cellular response to exogenous dsRNA (GO:0071360)2.76489227
110regulation of antigen receptor-mediated signaling pathway (GO:0050854)2.75750331
111positive regulation of antigen receptor-mediated signaling pathway (GO:0050857)2.75667588
112Arp2/3 complex-mediated actin nucleation (GO:0034314)2.73989426
113regulation of CD4-positive, alpha-beta T cell activation (GO:2000514)2.73687490
114positive thymic T cell selection (GO:0045059)2.73608398
115lymphocyte homeostasis (GO:0002260)2.71931849
116regulation of type I interferon-mediated signaling pathway (GO:0060338)2.69097248
117regulation of mast cell activation involved in immune response (GO:0033006)2.68668647
118positive regulation of cytokine biosynthetic process (GO:0042108)2.68036894
119antigen receptor-mediated signaling pathway (GO:0050851)2.67805611
120natural killer cell mediated cytotoxicity (GO:0042267)2.67548908
121natural killer cell mediated immunity (GO:0002228)2.67548908
122regulation of interleukin-12 biosynthetic process (GO:0045075)2.67459747
123regulation of nitric-oxide synthase biosynthetic process (GO:0051769)2.66580322
124regulation of interleukin-12 production (GO:0032655)2.66539281
125regulation of T-helper cell differentiation (GO:0045622)2.66048386
126response to interferon-gamma (GO:0034341)2.64493791
127positive regulation of toll-like receptor signaling pathway (GO:0034123)2.62068478
128positive regulation of type I interferon-mediated signaling pathway (GO:0060340)2.61833789
129response to muramyl dipeptide (GO:0032495)2.61262107
130negative regulation of granulocyte differentiation (GO:0030853)2.60364809
131T-helper 1 type immune response (GO:0042088)2.60056913
132regulation of mast cell activation (GO:0033003)2.58018146
133regulation of superoxide metabolic process (GO:0090322)2.57692100
134positive regulation of antigen processing and presentation (GO:0002579)2.56864373
135L-serine transport (GO:0015825)2.56347151
136T cell migration (GO:0072678)2.56271167
137positive regulation of leukocyte degranulation (GO:0043302)2.54531916
138germinal center formation (GO:0002467)2.53925220
139positive regulation of granulocyte macrophage colony-stimulating factor production (GO:0032725)2.53301537
140microglial cell activation (GO:0001774)2.49077610
141negative regulation of bone resorption (GO:0045779)2.47435517
142mature B cell differentiation (GO:0002335)2.47239026
143regulation of myeloid leukocyte mediated immunity (GO:0002886)2.46268858
144production of molecular mediator involved in inflammatory response (GO:0002532)2.45949941
145regulation of phagocytosis (GO:0050764)2.45864042
146dendritic cell differentiation (GO:0097028)2.43648582
147Peyers patch development (GO:0048541)2.42885848
148mucosal-associated lymphoid tissue development (GO:0048537)2.42885848
149antigen processing and presentation via MHC class Ib (GO:0002475)2.41072192
150T cell homeostasis (GO:0043029)2.40561975
151negative regulation of viral genome replication (GO:0045071)2.40022695
152pinocytosis (GO:0006907)2.38892823
153positive regulation of interferon-gamma biosynthetic process (GO:0045078)2.37055528
154triglyceride-rich lipoprotein particle remodeling (GO:0034370)2.35358419

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1IRF8_22096565_ChIP-ChIP_GC-B_Human5.80952219
2IRF8_21731497_ChIP-ChIP_J774_Mouse4.60069224
3IRF8_22096565_ChIP-ChIP_GC-B_Mouse3.95637160
4ESR1_17901129_ChIP-ChIP_LIVER_Mouse3.49109786
5E2F7_22180533_ChIP-Seq_HELA_Human3.42526053
6* IRF8_27001747_Chip-Seq_BMDM_Mouse3.38080863
7MECOM_23826213_ChIP-Seq_KASUMI_Mouse3.31819053
8IRF1_21803131_ChIP-Seq_MONOCYTES_Human3.19533411
9* SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse3.16382105
10BP1_19119308_ChIP-ChIP_Hs578T_Human3.16002064
11SPI1_22096565_ChIP-ChIP_GC-B_Mouse3.11762545
12FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse2.96495969
13FOXP3_17237761_ChIP-ChIP_TREG_Mouse2.90763602
14EGR1_23403033_ChIP-Seq_LIVER_Mouse2.87918400
15* NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse2.86373065
16SCL_19346495_ChIP-Seq_HPC-7_Human2.85653216
17GATA1_22025678_ChIP-Seq_K562_Human2.70044754
18STAT6_20620947_ChIP-Seq_CD4_POS_T_Human2.63573339
19MYB_21317192_ChIP-Seq_ERMYB_Mouse2.61742030
20EGR1_19374776_ChIP-ChIP_THP-1_Human2.57249927
21VDR_21846776_ChIP-Seq_THP-1_Human2.53668655
22MYC_22102868_ChIP-Seq_BL_Human2.45545825
23* RXR_22158963_ChIP-Seq_LIVER_Mouse2.25513884
24NOTCH1_21737748_ChIP-Seq_TLL_Human2.23737087
25STAT4_19710469_ChIP-ChIP_TH1__Mouse2.21873449
26* BRD4_27068464_Chip-Seq_AML-cells_Mouse2.18715543
27PPARA_22158963_ChIP-Seq_LIVER_Mouse2.18255883
28NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human2.12217994
29VDR_24763502_ChIP-Seq_THP-1_Human2.09704513
30Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse2.08837246
31* MYB_26560356_Chip-Seq_TH2_Human2.03694887
32NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse2.03561766
33RUNX1_20887958_ChIP-Seq_HPC-7_Mouse2.02977209
34* SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse2.01236048
35* SPI1_23547873_ChIP-Seq_NB4_Human2.01063889
36STAT3_20064451_ChIP-Seq_CD4+T_Mouse1.95629923
37BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse1.90665961
38CEBPA_23403033_ChIP-Seq_LIVER_Mouse1.90347398
39* RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human1.90228815
40RUNX_20019798_ChIP-Seq_JUKART_Human1.90053715
41* MAF_26560356_Chip-Seq_TH1_Human1.89901765
42FOXM1_23109430_ChIP-Seq_U2OS_Human1.80271248
43E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human1.80155811
44* MYB_26560356_Chip-Seq_TH1_Human1.78001884
45CIITA_25753668_ChIP-Seq_RAJI_Human1.77442154
46RUNX1_22412390_ChIP-Seq_EML_Mouse1.75072071
47LXR_22158963_ChIP-Seq_LIVER_Mouse1.73702269
48STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse1.71261685
49ASXL1_24218140_ChIP-Seq_BMDM_Mouse1.71254184
50FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse1.69899409
51FLI1_20887958_ChIP-Seq_HPC-7_Mouse1.62946492
52* UTX_26944678_Chip-Seq_JUKART_Human1.60467333
53GATA2_22383799_ChIP-Seq_G1ME_Mouse1.59216930
54SPI1_23127762_ChIP-Seq_K562_Human1.52291707
55STAT5_23275557_ChIP-Seq_MAMMARY-EPITHELIUM_Mouse1.48910901
56CEBPB_23403033_ChIP-Seq_LIVER_Mouse1.47520402
57TCF7_22412390_ChIP-Seq_EML_Mouse1.47335485
58GATA1_22383799_ChIP-Seq_G1ME_Mouse1.45825673
59PU_27001747_Chip-Seq_BMDM_Mouse1.45168564
60VDR_23849224_ChIP-Seq_CD4+_Human1.41313321
61LMO2_20887958_ChIP-Seq_HPC-7_Mouse1.39922288
62TAL1_20887958_ChIP-Seq_HPC-7_Mouse1.38829717
63* TAL1_20566737_ChIP-Seq_PRIMARY_FETAL_LIVER_ERYTHROID_Mouse1.34773521
64MEIS1_20887958_ChIP-Seq_HPC-7_Mouse1.33674287
65SMAD_19615063_ChIP-ChIP_OVARY_Human1.32493159
66CEBPB_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse1.31898057
67E2F1_21310950_ChIP-Seq_MCF-7_Human1.29802811
68FOXP3_21729870_ChIP-Seq_TREG_Human1.25986696
69HOXB4_20404135_ChIP-ChIP_EML_Mouse1.24550502
70PPARG_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse1.24421021
71PPARG_19300518_ChIP-PET_3T3-L1_Mouse1.23982516
72* ERG_20887958_ChIP-Seq_HPC-7_Mouse1.21141600
73LYL1_20887958_ChIP-Seq_HPC-7_Mouse1.20386627
74SFPI1_20887958_ChIP-Seq_HPC-7_Mouse1.19783682
75THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse1.19240638
76TFEB_21752829_ChIP-Seq_HELA_Human1.19225067
77CREB1_15753290_ChIP-ChIP_HEK293T_Human1.18558687
78CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human1.16240215
79GATA1_19941827_ChIP-Seq_MEL_Mouse1.15153764
80VDR_24787735_ChIP-Seq_THP-1_Human1.12703043
81GATA3_27048872_Chip-Seq_THYMUS_Human1.12568030
82CEBPB_20176806_ChIP-Seq_MACROPHAGES_Mouse1.12263769
83GATA2_20887958_ChIP-Seq_HPC-7_Mouse1.10387586
84NFE2L2_22581777_ChIP-Seq_LYMPHOBLASTOID_Human1.10260195
85KDM2B_26808549_Chip-Seq_HPB-ALL_Human1.09314905
86TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse1.08129389
87SOX9_22984422_ChIP-ChIP_TESTIS_Rat1.03897331
88FOXO1_23066095_ChIP-Seq_LIVER_Mouse1.03586494
89ELF1_17652178_ChIP-ChIP_JURKAT_Human1.03194083
90E2F4_17652178_ChIP-ChIP_JURKAT_Human1.00295496
91PPARG_20176806_ChIP-Seq_MACROPHAGES_Mouse1.00169519
92MAF_26560356_Chip-Seq_TH2_Human0.98307847
93* ELK3_25401928_ChIP-Seq_HUVEC_Human0.98025350
94GATA1_19941826_ChIP-Seq_K562_Human0.97464252
95EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse0.96946843
96DCP1A_22483619_ChIP-Seq_HELA_Human0.96714247
97KDM2B_26808549_Chip-Seq_SUP-B15_Human0.96665584
98GATA2_21666600_ChIP-Seq_HMVEC_Human0.95702391
99GFI1B_20887958_ChIP-Seq_HPC-7_Mouse0.95202867
100TP63_17297297_ChIP-ChIP_HaCaT_Human0.94316103
101FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse0.90566382
102PU.1_20513432_ChIP-Seq_Bcells_Mouse0.90493589
103NELFA_20434984_ChIP-Seq_ESCs_Mouse0.90442963
104CEBPA_20513432_ChIP-Seq_MACROPHAGES_Mouse0.90420108
105VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human0.90121953
106PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse0.89057211
107MYC_18555785_ChIP-Seq_MESCs_Mouse0.88627746
108PU.1_20513432_ChIP-Seq_MACROPHAGES_Mouse0.88334713
109CEBPB_20513432_ChIP-Seq_MACROPHAGES_Mouse0.88182906
110SPI1_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse0.88137927
111FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human0.87655963
112HNF4A_19761587_ChIP-ChIP_CACO-2_Human0.87542921
113EST1_17652178_ChIP-ChIP_JURKAT_Human0.86627453
114* GATA3_26560356_Chip-Seq_TH2_Human0.85851381
115PU.1_20176806_ChIP-Seq_MACROPHAGES_Mouse0.84925848
116KDM2B_26808549_Chip-Seq_SIL-ALL_Human0.84113013
117RUNX1_17652178_ChIP-ChIP_JURKAT_Human0.83720573
118MYC_19030024_ChIP-ChIP_MESCs_Mouse0.83515301
119GATA2_19941826_ChIP-Seq_K562_Human0.83335880
120MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse0.81462823
121MYC_19079543_ChIP-ChIP_MESCs_Mouse0.79708593
122E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human0.79177615
123KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human0.75304240
124MYC_18358816_ChIP-ChIP_MESCs_Mouse0.74550126

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0001835_abnormal_antigen_presentation4.01709076
2MP0003436_decreased_susceptibility_to3.24215375
3MP0009785_altered_susceptibility_to3.08723525
4MP0000685_abnormal_immune_system3.00916507
5MP0001800_abnormal_humoral_immune2.89111505
6MP0003303_peritoneal_inflammation2.76389053
7MP0005387_immune_system_phenotype2.68334398
8MP0001790_abnormal_immune_system2.68334398
9MP0008057_abnormal_DNA_replication2.63202315
10MP0002452_abnormal_antigen_presenting2.58755561
11MP0002419_abnormal_innate_immunity2.51855459
12MP0005025_abnormal_response_to2.51533759
13MP0005360_urolithiasis2.49140109
14MP0003191_abnormal_cellular_cholesterol2.46561731
15MP0005000_abnormal_immune_tolerance2.45610659
16MP0002148_abnormal_hypersensitivity_rea2.43010131
17MP0002723_abnormal_immune_serum2.35917848
18MP0002139_abnormal_hepatobiliary_system2.35696068
19MP0005464_abnormal_platelet_physiology2.33492040
20MP0003724_increased_susceptibility_to2.32251898
21MP0002166_altered_tumor_susceptibility2.21452445
22MP0005671_abnormal_response_to2.18314930
23MP0001819_abnormal_immune_cell2.16163173
24MP0002420_abnormal_adaptive_immunity2.15355679
25MP0005451_abnormal_body_composition2.14636893
26MP0009840_abnormal_foam_cell2.08448594
27MP0002396_abnormal_hematopoietic_system2.08274582
28MP0006054_spinal_hemorrhage2.07610949
29MP0006082_CNS_inflammation1.99381164
30MP0009278_abnormal_bone_marrow1.96293421
31MP0001853_heart_inflammation1.94799385
32MP0002398_abnormal_bone_marrow1.93869639
33MP0010155_abnormal_intestine_physiology1.88775332
34MP0003300_gastrointestinal_ulcer1.85575444
35MP0000716_abnormal_immune_system1.83133708
36MP0000689_abnormal_spleen_morphology1.82594147
37MP0002006_tumorigenesis1.76745573
38MP0002877_abnormal_melanocyte_morpholog1.75287124
39MP0005397_hematopoietic_system_phenotyp1.72769733
40MP0001545_abnormal_hematopoietic_system1.72769733
41MP0001845_abnormal_inflammatory_respons1.72037908
42MP0010094_abnormal_chromosome_stability1.71838089
43MP0005058_abnormal_lysosome_morphology1.68615128
44MP0004947_skin_inflammation1.66551916
45MP0001533_abnormal_skeleton_physiology1.63419147
46MP0002722_abnormal_immune_system1.61410137
47MP0008469_abnormal_protein_level1.61367913
48MP0005085_abnormal_gallbladder_physiolo1.60881656
49MP0004808_abnormal_hematopoietic_stem1.59202434
50MP0002429_abnormal_blood_cell1.57047500
51MP0002405_respiratory_system_inflammati1.55851922
52MP0009764_decreased_sensitivity_to1.52907591
53MP0003656_abnormal_erythrocyte_physiolo1.48214631
54MP0005365_abnormal_bile_salt1.47681364
55MP0003183_abnormal_peptide_metabolism1.34376199
56MP0004510_myositis1.33996525
57MP0002009_preneoplasia1.31410960
58MP0002163_abnormal_gland_morphology1.27799639
59MP0002138_abnormal_hepatobiliary_system1.27415136
60MP0003077_abnormal_cell_cycle1.22595619
61MP0008875_abnormal_xenobiotic_pharmacok1.22326719
62MP0010329_abnormal_lipoprotein_level1.21913144
63MP0003075_altered_response_to1.20195316
64MP0000609_abnormal_liver_physiology1.18670845
65MP0001873_stomach_inflammation1.18151329
66MP0000490_abnormal_crypts_of1.17981503
67MP0000465_gastrointestinal_hemorrhage1.17793775
68MP0001348_abnormal_lacrimal_gland1.17669796
69MP0003172_abnormal_lysosome_physiology1.15587934
70MP0003111_abnormal_nucleus_morphology1.14862033
71MP0003693_abnormal_embryo_hatching1.13374046
72MP0009763_increased_sensitivity_to1.12367772
73MP0003252_abnormal_bile_duct1.10794521
74MP0005166_decreased_susceptibility_to1.10597148
75MP0009333_abnormal_splenocyte_physiolog1.08625508
76MP0008260_abnormal_autophagy1.07126072
77MP0000703_abnormal_thymus_morphology1.06454771
78MP0003866_abnormal_defecation1.05935877
79MP0004381_abnormal_hair_follicle1.05706742
80MP0001879_abnormal_lymphatic_vessel1.04517310
81MP0003186_abnormal_redox_activity0.99852370
82MP0005319_abnormal_enzyme/_coenzyme0.96796230
83MP0000604_amyloidosis0.96377419
84MP0003221_abnormal_cardiomyocyte_apopto0.94856826
85MP0003763_abnormal_thymus_physiology0.94209066
86MP0000598_abnormal_liver_morphology0.92471500
87MP0005083_abnormal_biliary_tract0.90904259
88MP0010234_abnormal_vibrissa_follicle0.90786882
89MP0002254_reproductive_system_inflammat0.90668599
90MP0000343_altered_response_to0.89634395
91MP0002998_abnormal_bone_remodeling0.89632101
92MP0005584_abnormal_enzyme/coenzyme_acti0.88001107
93MP0002019_abnormal_tumor_incidence0.86895270
94MP0005174_abnormal_tail_pigmentation0.86595786
95MP0005310_abnormal_salivary_gland0.86156297
96MP0005075_abnormal_melanosome_morpholog0.85980672
97MP0000249_abnormal_blood_vessel0.85794242
98MP0003045_fibrosis0.84772318
99MP0001663_abnormal_digestive_system0.83497382
100MP0010307_abnormal_tumor_latency0.83482844
101MP0001666_abnormal_nutrient_absorption0.83143410
102MP0001851_eye_inflammation0.82824216
103MP0002933_joint_inflammation0.82668751
104MP0003448_altered_tumor_morphology0.82293176
105MP0003091_abnormal_cell_migration0.81985192
106MP0000858_altered_metastatic_potential0.81643152
107MP0005084_abnormal_gallbladder_morpholo0.80457942
108MP0002928_abnormal_bile_duct0.79860454
109MP0002277_abnormal_respiratory_mucosa0.79404618
110MP0002136_abnormal_kidney_physiology0.79400079
111MP0004957_abnormal_blastocyst_morpholog0.78030504
112MP0000313_abnormal_cell_death0.76834187
113MP0002132_abnormal_respiratory_system0.76616331
114MP0000015_abnormal_ear_pigmentation0.76587277
115MP0003806_abnormal_nucleotide_metabolis0.76190727
116MP0000350_abnormal_cell_proliferation0.75771699
117MP0008873_increased_physiological_sensi0.74098720
118MP0003943_abnormal_hepatobiliary_system0.72616135
119MP0005164_abnormal_response_to0.71164662
120MP0005645_abnormal_hypothalamus_physiol0.69671660
121MP0001915_intracranial_hemorrhage0.69434585
122MP0009643_abnormal_urine_homeostasis0.68660234
123MP0010352_gastrointestinal_tract_polyps0.68607462
124MP0002693_abnormal_pancreas_physiology0.66066890
125MP0003786_premature_aging0.65947534
126MP0005332_abnormal_amino_acid0.64954442
127MP0008058_abnormal_DNA_repair0.63865634
128MP0005621_abnormal_cell_physiology0.63165003
129MP0005390_skeleton_phenotype0.61229436
130MP0003453_abnormal_keratinocyte_physiol0.61108175
131MP0008874_decreased_physiological_sensi0.54551838
132MP0005076_abnormal_cell_differentiation0.53377375
133MP0008961_abnormal_basal_metabolism0.52062074
134MP0006035_abnormal_mitochondrial_morpho0.51789874

Predicted human phenotypes

RankGene SetZ-score
1Cellulitis (HP:0100658)5.43454822
2Agammaglobulinemia (HP:0004432)5.20278803
3Recurrent bacterial skin infections (HP:0005406)4.93378316
4Recurrent abscess formation (HP:0002722)4.72725612
5IgA deficiency (HP:0002720)4.53933617
6Abnormality of B cell number (HP:0010975)4.28568122
7B lymphocytopenia (HP:0010976)4.28568122
8Recurrent viral infections (HP:0004429)4.24992887
9Recurrent gram-negative bacterial infections (HP:0005420)4.11025636
10Thyroiditis (HP:0100646)4.08485467
11Verrucae (HP:0200043)4.06296630
12Papilloma (HP:0012740)4.06296630
13Eczematoid dermatitis (HP:0000976)3.97204814
14Meningitis (HP:0001287)3.95525203
15Autoimmune hemolytic anemia (HP:0001890)3.82663365
16Recurrent fungal infections (HP:0002841)3.66141865
17Osteomyelitis (HP:0002754)3.64981571
18Optic neuritis (HP:0100653)3.64196172
19Retrobulbar optic neuritis (HP:0100654)3.64196172
20Systemic lupus erythematosus (HP:0002725)3.59619717
21Increased IgM level (HP:0003496)3.56218065
22Pulmonary infiltrates (HP:0002113)3.40060217
23Panhypogammaglobulinemia (HP:0003139)3.39987243
24Colitis (HP:0002583)3.39873303
25Autoimmune thrombocytopenia (HP:0001973)3.38464839
26Recurrent skin infections (HP:0001581)3.32417850
27Elevated erythrocyte sedimentation rate (HP:0003565)3.30307647
28Recurrent bronchitis (HP:0002837)3.29394812
29Hypoplasia of the thymus (HP:0000778)3.28870317
30Encephalitis (HP:0002383)3.28483673
31Chronic otitis media (HP:0000389)3.24964952
32Inflammation of the large intestine (HP:0002037)3.21252455
33Sepsis (HP:0100806)3.13922390
34Gastrointestinal inflammation (HP:0004386)3.12701868
35Mediastinal lymphadenopathy (HP:0100721)3.11112930
36Myositis (HP:0100614)3.10379084
37Chronic diarrhea (HP:0002028)3.09231283
38Emphysema (HP:0002097)3.03975123
39Severe combined immunodeficiency (HP:0004430)3.01504018
40Pustule (HP:0200039)3.00077722
41Joint hemorrhage (HP:0005261)2.99041826
42Recurrent pneumonia (HP:0006532)2.98289514
43Complement deficiency (HP:0004431)2.97257159
44Gastrointestinal infarctions (HP:0005244)2.96746125
45Gingival bleeding (HP:0000225)2.96180931
46Glomerulonephritis (HP:0000099)2.95990877
47Mitral stenosis (HP:0001718)2.93330113
48Lymphoma (HP:0002665)2.92935835
49Eosinophilia (HP:0001880)2.91114862
50Keratoconjunctivitis sicca (HP:0001097)2.88959129
51Combined immunodeficiency (HP:0005387)2.84819662
52Thrombocytosis (HP:0001894)2.84548127
53Abnormality of macrophages (HP:0004311)2.81588432
54Fatigue (HP:0012378)2.79430400
55Periodontitis (HP:0000704)2.78656811
56Spontaneous hematomas (HP:0007420)2.76249489
57Vasculitis (HP:0002633)2.71236996
58Skin rash (HP:0000988)2.58635190
59Restrictive lung disease (HP:0002091)2.58396436
60Deep venous thrombosis (HP:0002625)2.57390822
61Abnormality of complement system (HP:0005339)2.56849058
62Hemoptysis (HP:0002105)2.55786357
63Obstructive lung disease (HP:0006536)2.55553971
64Chronic obstructive pulmonary disease (HP:0006510)2.55553971
65Granulocytopenia (HP:0001913)2.55319441
66Keratoconjunctivitis (HP:0001096)2.54892294
67IgM deficiency (HP:0002850)2.54069370
68Vacuolated lymphocytes (HP:0001922)2.53918963
69Recurrent lower respiratory tract infections (HP:0002783)2.53261907
70Chronic sinusitis (HP:0011109)2.52444600
71Epistaxis (HP:0000421)2.50604337
72Interstitial pulmonary disease (HP:0006530)2.47820039
73Stomatitis (HP:0010280)2.45979236
74Hypergammaglobulinemia (HP:0010702)2.45452259
75Chest pain (HP:0100749)2.43944647
76Viral hepatitis (HP:0006562)2.43585859
77Prolonged bleeding time (HP:0003010)2.42072404
78Gangrene (HP:0100758)2.38346878
79Myocardial infarction (HP:0001658)2.37962000
80Petechiae (HP:0000967)2.37013349
81Leukocytosis (HP:0001974)2.36117069
82Abnormality of T cell number (HP:0011839)2.35601007
83Abnormality of eosinophils (HP:0001879)2.34858847
84Prolonged partial thromboplastin time (HP:0003645)2.34517906
85T lymphocytopenia (HP:0005403)2.34162306
86Small epiphyses (HP:0010585)2.33702497
87Increased cerebral lipofuscin (HP:0011813)2.33154723
88Abnormality of the pleura (HP:0002103)2.32442315
89Acute hepatic failure (HP:0006554)2.30658683
90Leukopenia (HP:0001882)2.30145311
91Hematochezia (HP:0002573)2.29840985
92Abnormality of monocarboxylic acid metabolism (HP:0010996)2.29308406
93Neoplasm of the tracheobronchial system (HP:0100552)2.29208990
94Chronic mucocutaneous candidiasis (HP:0002728)2.28027515
95Recurrent cutaneous fungal infections (HP:0011370)2.28027515
96Gingivitis (HP:0000230)2.27358871
97Bronchitis (HP:0012387)2.27183587
98Alveolar cell carcinoma (HP:0006519)2.26838074
99Urticaria (HP:0001025)2.23757975
100Recurrent sinusitis (HP:0011108)2.22721685
101Abnormality of the common coagulation pathway (HP:0010990)2.22092262
102Abnormality of T cells (HP:0002843)2.21148762
103Parkinsonism with favorable response to dopaminergic medication (HP:0002548)2.20740856
104Premature loss of primary teeth (HP:0006323)2.19035838
105Arthralgia (HP:0002829)2.15735724
106Increased neuronal autofluorescent lipopigment (HP:0002074)2.15161052
107Gastrointestinal stroma tumor (HP:0100723)2.14894002
108Skin ulcer (HP:0200042)2.14808474
109Xerostomia (HP:0000217)2.14267933
110Hypertensive crisis (HP:0100735)2.12748162
111Primitive reflexes (palmomental, snout, glabellar) (HP:0002476)2.10626417
112Joint swelling (HP:0001386)2.08245955
113Abnormality of T cell physiology (HP:0011840)2.05879760
114Aplasia/Hypoplasia of the thymus (HP:0010515)2.05455839
115Hypoproteinemia (HP:0003075)2.04126770
116Abnormality of the intervertebral disk (HP:0005108)2.04114031
117Orchitis (HP:0100796)2.02301514
118Lymphopenia (HP:0001888)2.01799179
119IgG deficiency (HP:0004315)2.00560453
120Abnormality of aromatic amino acid family metabolism (HP:0004338)2.00053820
121Nephritis (HP:0000123)1.99981307
122Amyloidosis (HP:0011034)1.99425559
123Loss of speech (HP:0002371)1.98939376
124Impaired platelet aggregation (HP:0003540)1.98669085
125Abnormal platelet function (HP:0011869)1.98669085
126Anorexia (HP:0002039)1.98342941
127Tetraparesis (HP:0002273)1.97802491
128Abnormality of cells of the lymphoid lineage (HP:0012140)1.97781934
129Abnormal delayed hypersensitivity skin test (HP:0002963)1.97093553
130Arterial thrombosis (HP:0004420)1.95477094
131Neutropenia (HP:0001875)1.95003663
132Abnormality of the prostate (HP:0008775)1.94984172
133Basal cell carcinoma (HP:0002671)1.93238990
134Purpura (HP:0000979)1.91370781
135Thrombophlebitis (HP:0004418)1.91249405
136Increased IgE level (HP:0003212)1.91095613
137Pulmonary fibrosis (HP:0002206)1.88689505
138Abnormality of male internal genitalia (HP:0000022)1.85248857
139Hepatitis (HP:0012115)1.80621953

Predicted kinase interactions (KEA)

RankGene SetZ-score
1MAP3K105.53298349
2ERN14.25309181
3PRPF4B3.34014201
4BLK3.24428983
5RIPK42.79255143
6MAP4K12.70479449
7TYK22.70305414
8TBK12.65926819
9MAP3K142.48047327
10GRK62.43258699
11STK242.21638663
12KIT2.06929943
13BMPR22.06882768
14CSF1R2.01900148
15EEF2K1.96665988
16SYK1.87960842
17IRAK41.82811515
18BTK1.81244987
19IKBKE1.77699872
20TGFBR21.75760986
21STK41.64788535
22JAK11.59915480
23IRAK31.56864502
24IKBKB1.54466406
25TLK11.53822268
26TAOK31.53432488
27TESK21.50929526
28PIM11.47621230
29STK101.43043834
30TEC1.40463406
31LYN1.40079720
32ARAF1.40070581
33JAK31.31931366
34FGFR41.30078635
35MAP3K91.29735275
36MATK1.27458894
37FES1.27230667
38TAF11.26712267
39TAOK21.24367440
40MAP2K31.19590186
41ZAP701.18016972
42CDK41.14325820
43NEK91.12344669
44IRAK21.12008453
45MAPK111.11403669
46SIK31.10123929
47PASK1.09584785
48RPS6KA41.08572304
49CSK1.08557177
50FRK1.07125223
51PKN21.06843173
52CLK11.06343632
53HCK1.05355715
54EIF2AK31.04875978
55IRAK11.03335783
56LRRK20.99821898
57MAPK40.97968066
58MAP3K50.94609818
59FLT30.93815007
60CCNB10.93406383
61SIK20.93024345
62FGFR30.92412333
63JAK20.92008091
64TRIB30.88577471
65LCK0.88495244
66MAP3K130.86975223
67CDK60.85361441
68BUB10.84771892
69SMG10.83613427
70NLK0.83065236
71BRAF0.79881380
72MELK0.79387893
73CDK90.78262213
74CDK190.78206104
75KSR20.75628563
76CHUK0.75411642
77PRKCI0.73978383
78TGFBR10.72964265
79DYRK1B0.72425014
80PIM20.71721381
81CDC70.71178569
82PRKCQ0.68640821
83PBK0.66458054
84BRD40.66446483
85RPS6KB20.65890559
86ITK0.65075356
87VRK10.64985702
88KDR0.64928209
89EPHB10.64158378
90MST40.63800773
91FGR0.62488426
92MAP3K10.61654799
93PTK60.61304982
94MAPK120.60982828
95RAF10.60079967
96NEK20.57478868
97TRPM70.56703559
98MARK30.54610292
99PDK10.54371887
100SIK10.54097644
101HIPK20.53052476
102PIK3CG0.52223764
103EIF2AK20.52194472
104DYRK30.51509929
105ZAK0.51343329
106MAP3K80.50376974
107MOS0.49196759
108RIPK10.48195890
109ABL10.45782407
110SCYL20.45545424
111EIF2AK10.44927459
112TXK0.44830885
113PRKCD0.42716615
114RPS6KA50.42646751
115STK30.42314360
116MAPKAPK30.39361427
117MAP3K30.39330647
118EGFR0.39273458
119MST1R0.39140210
120CDK120.37845796
121MAPKAPK20.37224513
122ACVR1B0.36201605
123MAPK70.34984505
124NME20.34953486
125CAMK1D0.33677934
126MAP3K110.33223206
127YES10.31879516
128SGK30.28865161
129MAP3K70.28438468
130RPS6KA60.26794805
131EPHA30.26340537

Predicted pathways (KEGG)

RankGene SetZ-score
1Autoimmune thyroid disease_Homo sapiens_hsa053203.45564075
2Staphylococcus aureus infection_Homo sapiens_hsa051503.38485002
3Primary immunodeficiency_Homo sapiens_hsa053403.02536705
4B cell receptor signaling pathway_Homo sapiens_hsa046623.00022408
5Type I diabetes mellitus_Homo sapiens_hsa049402.74169071
6Leishmaniasis_Homo sapiens_hsa051402.66610868
7NF-kappa B signaling pathway_Homo sapiens_hsa040642.34984214
8Osteoclast differentiation_Homo sapiens_hsa043802.27290700
9Complement and coagulation cascades_Homo sapiens_hsa046102.19768662
10Toll-like receptor signaling pathway_Homo sapiens_hsa046202.16976872
11Viral myocarditis_Homo sapiens_hsa054162.04631064
12Systemic lupus erythematosus_Homo sapiens_hsa053222.01699081
13Primary bile acid biosynthesis_Homo sapiens_hsa001202.01135565
14Caffeine metabolism_Homo sapiens_hsa002321.96256889
15RIG-I-like receptor signaling pathway_Homo sapiens_hsa046221.92575526
16Intestinal immune network for IgA production_Homo sapiens_hsa046721.87272609
17Measles_Homo sapiens_hsa051621.82725233
18Cytosolic DNA-sensing pathway_Homo sapiens_hsa046231.82565200
19Pertussis_Homo sapiens_hsa051331.82313639
20NOD-like receptor signaling pathway_Homo sapiens_hsa046211.63261235
21Tuberculosis_Homo sapiens_hsa051521.60802843
22Ascorbate and aldarate metabolism_Homo sapiens_hsa000531.60511835
23Pentose and glucuronate interconversions_Homo sapiens_hsa000401.59735071
24Influenza A_Homo sapiens_hsa051641.58687103
25Legionellosis_Homo sapiens_hsa051341.57692338
26Non-homologous end-joining_Homo sapiens_hsa034501.51342805
27Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007601.49528113
28T cell receptor signaling pathway_Homo sapiens_hsa046601.48959313
29Herpes simplex infection_Homo sapiens_hsa051681.47601925
30Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046661.43643823
31Malaria_Homo sapiens_hsa051441.42548156
32Antigen processing and presentation_Homo sapiens_hsa046121.34959676
33Hematopoietic cell lineage_Homo sapiens_hsa046401.33964478
34Glycosaminoglycan degradation_Homo sapiens_hsa005311.30647135
35Toxoplasmosis_Homo sapiens_hsa051451.27697352
36Fc epsilon RI signaling pathway_Homo sapiens_hsa046641.23746436
37TNF signaling pathway_Homo sapiens_hsa046681.21678099
38Apoptosis_Homo sapiens_hsa042101.18780694
39Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046501.16542800
40Nitrogen metabolism_Homo sapiens_hsa009101.16065467
41Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005321.15200896
42Inflammatory bowel disease (IBD)_Homo sapiens_hsa053211.14693098
43Butirosin and neomycin biosynthesis_Homo sapiens_hsa005241.10631481
44Other glycan degradation_Homo sapiens_hsa005111.10514442
45Chagas disease (American trypanosomiasis)_Homo sapiens_hsa051421.08326378
46Jak-STAT signaling pathway_Homo sapiens_hsa046301.05851527
47Arginine biosynthesis_Homo sapiens_hsa002201.03602956
48Hepatitis C_Homo sapiens_hsa051601.02614638
49Hepatitis B_Homo sapiens_hsa051610.99145779
50ABC transporters_Homo sapiens_hsa020100.98331492
51HTLV-I infection_Homo sapiens_hsa051660.98271487
52Drug metabolism - other enzymes_Homo sapiens_hsa009830.97866144
53Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.97709946
54Shigellosis_Homo sapiens_hsa051310.96640575
55Lysosome_Homo sapiens_hsa041420.96447087
56African trypanosomiasis_Homo sapiens_hsa051430.95246685
57Pentose phosphate pathway_Homo sapiens_hsa000300.94190551
58Transcriptional misregulation in cancer_Homo sapiens_hsa052020.92853512
59Tryptophan metabolism_Homo sapiens_hsa003800.91510021
60DNA replication_Homo sapiens_hsa030300.90720730
61Salmonella infection_Homo sapiens_hsa051320.90631292
62Chemokine signaling pathway_Homo sapiens_hsa040620.90233476
63Viral carcinogenesis_Homo sapiens_hsa052030.88478763
64Chronic myeloid leukemia_Homo sapiens_hsa052200.85856335
65Peroxisome_Homo sapiens_hsa041460.84127478
66Histidine metabolism_Homo sapiens_hsa003400.82839107
67Cell cycle_Homo sapiens_hsa041100.82435155
68p53 signaling pathway_Homo sapiens_hsa041150.81504674
69Platelet activation_Homo sapiens_hsa046110.80822442
70Acute myeloid leukemia_Homo sapiens_hsa052210.79564066
71Leukocyte transendothelial migration_Homo sapiens_hsa046700.78165143
72Base excision repair_Homo sapiens_hsa034100.76335413
73Folate biosynthesis_Homo sapiens_hsa007900.75969616
74Cytokine-cytokine receptor interaction_Homo sapiens_hsa040600.75356305
75Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004000.72876501
76Selenocompound metabolism_Homo sapiens_hsa004500.71556683
77Fatty acid degradation_Homo sapiens_hsa000710.71046809
78Pancreatic cancer_Homo sapiens_hsa052120.70314404
79PPAR signaling pathway_Homo sapiens_hsa033200.68060456
80Allograft rejection_Homo sapiens_hsa053300.66783100
81Homologous recombination_Homo sapiens_hsa034400.65696971
82Prolactin signaling pathway_Homo sapiens_hsa049170.65358580
83Renin-angiotensin system_Homo sapiens_hsa046140.65076709
84Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.62909205
85AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049330.59909633
86Renal cell carcinoma_Homo sapiens_hsa052110.59513398
87Graft-versus-host disease_Homo sapiens_hsa053320.59100221
88Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.56832969
89Non-small cell lung cancer_Homo sapiens_hsa052230.56476274
90Asthma_Homo sapiens_hsa053100.54445097
91RNA degradation_Homo sapiens_hsa030180.54063061
92Starch and sucrose metabolism_Homo sapiens_hsa005000.53973432
93Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.53763713
94Alcoholism_Homo sapiens_hsa050340.53315001
95Epstein-Barr virus infection_Homo sapiens_hsa051690.53227240
96Small cell lung cancer_Homo sapiens_hsa052220.53038125
97Chemical carcinogenesis_Homo sapiens_hsa052040.52869966
98Insulin resistance_Homo sapiens_hsa049310.50802744
99Nucleotide excision repair_Homo sapiens_hsa034200.49129639
100Carbohydrate digestion and absorption_Homo sapiens_hsa049730.48321388
101Prostate cancer_Homo sapiens_hsa052150.45851011
102Steroid hormone biosynthesis_Homo sapiens_hsa001400.45837178
103Drug metabolism - cytochrome P450_Homo sapiens_hsa009820.44611094
104Adipocytokine signaling pathway_Homo sapiens_hsa049200.44311318
105Fanconi anemia pathway_Homo sapiens_hsa034600.43905194
106Vitamin digestion and absorption_Homo sapiens_hsa049770.43183222
107Phagosome_Homo sapiens_hsa041450.42206517
108Mismatch repair_Homo sapiens_hsa034300.41487059
109Rheumatoid arthritis_Homo sapiens_hsa053230.41443253
110Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010400.40364535
111Neurotrophin signaling pathway_Homo sapiens_hsa047220.39666631
112Sulfur relay system_Homo sapiens_hsa041220.38737420
113Proteasome_Homo sapiens_hsa030500.38657147
114HIF-1 signaling pathway_Homo sapiens_hsa040660.37867506
115FoxO signaling pathway_Homo sapiens_hsa040680.37694671
116Sphingolipid signaling pathway_Homo sapiens_hsa040710.36943374
117Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.33745078
118Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.33503187
119Bacterial invasion of epithelial cells_Homo sapiens_hsa051000.32840257
120Spliceosome_Homo sapiens_hsa030400.32821814
121Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030080.32624305
122Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.32432571
123Lysine degradation_Homo sapiens_hsa003100.32106534
124Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.31947907
125Dorso-ventral axis formation_Homo sapiens_hsa043200.30095559
126Colorectal cancer_Homo sapiens_hsa052100.30021170
127mTOR signaling pathway_Homo sapiens_hsa041500.29942601
128Bladder cancer_Homo sapiens_hsa052190.29621367
129Ribosome_Homo sapiens_hsa030100.29555435
130Basal transcription factors_Homo sapiens_hsa030220.29437595
131Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.29091941
132Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.28411773
133Thyroid cancer_Homo sapiens_hsa052160.27931839
134Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.26750016
135VEGF signaling pathway_Homo sapiens_hsa043700.26461806
136Pyrimidine metabolism_Homo sapiens_hsa002400.22382270
137Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.21834646
138SNARE interactions in vesicular transport_Homo sapiens_hsa041300.21284416
139Phosphatidylinositol signaling system_Homo sapiens_hsa040700.19772043
140Endometrial cancer_Homo sapiens_hsa052130.19180974

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