THOC3

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: This gene encodes a component of the nuclear THO transcription elongation complex, which is part of the larger transcription export (TREX) complex that couples messenger RNA processing and export. In humans, the transcription export complex is recruited to the 5'-end of messenger RNAs in a splicing- and cap-dependent manner. Studies of a related complex in mouse suggest that the metazoan transcription export complex is involved in cell differentiation and development. A pseudogene of this gene has been defined on chromosome 5. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1DNA deamination (GO:0045006)5.29958614
2maturation of SSU-rRNA (GO:0030490)4.78880011
3DNA strand elongation involved in DNA replication (GO:0006271)4.77294143
4ribosomal small subunit assembly (GO:0000028)4.65874042
5DNA replication initiation (GO:0006270)4.54665074
6DNA strand elongation (GO:0022616)4.51604025
7telomere maintenance via semi-conservative replication (GO:0032201)4.43750242
8viral transcription (GO:0019083)4.43117678
9translational termination (GO:0006415)4.36942071
10formation of translation preinitiation complex (GO:0001731)4.31996808
11nucleobase biosynthetic process (GO:0046112)4.31977764
12regulation of mitochondrial translation (GO:0070129)4.31511407
13DNA unwinding involved in DNA replication (GO:0006268)4.25867369
14establishment of viral latency (GO:0019043)4.25349885
15purine nucleobase biosynthetic process (GO:0009113)4.22296313
16DNA replication checkpoint (GO:0000076)4.17940304
17ribosomal large subunit biogenesis (GO:0042273)4.12488129
18ribosome biogenesis (GO:0042254)4.06583721
19proteasome assembly (GO:0043248)4.03278782
20ribosomal small subunit biogenesis (GO:0042274)4.03016823
21ribonucleoprotein complex biogenesis (GO:0022613)4.02795085
22translational elongation (GO:0006414)3.99291782
23translational initiation (GO:0006413)3.97452166
24spliceosomal snRNP assembly (GO:0000387)3.93863628
25telomere maintenance via recombination (GO:0000722)3.88409232
26mitotic metaphase plate congression (GO:0007080)3.80461076
27ribosome assembly (GO:0042255)3.78438539
28protein localization to kinetochore (GO:0034501)3.71600548
29SRP-dependent cotranslational protein targeting to membrane (GO:0006614)3.71529662
30nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184)3.70483027
31rRNA processing (GO:0006364)3.69902304
32mitotic recombination (GO:0006312)3.67039865
33CENP-A containing nucleosome assembly (GO:0034080)3.63591655
34folic acid-containing compound biosynthetic process (GO:0009396)3.63366881
35cotranslational protein targeting to membrane (GO:0006613)3.62837180
36protein targeting to ER (GO:0045047)3.61247368
37mitotic sister chromatid segregation (GO:0000070)3.59506002
38chromatin remodeling at centromere (GO:0031055)3.59086344
39rRNA metabolic process (GO:0016072)3.57187863
40DNA replication-dependent nucleosome organization (GO:0034723)3.57182707
41DNA replication-dependent nucleosome assembly (GO:0006335)3.57182707
42DNA ligation (GO:0006266)3.54197342
43mitochondrial ATP synthesis coupled proton transport (GO:0042776)3.53551211
44regulation of transcription involved in G1/S transition of mitotic cell cycle (GO:0000083)3.53281528
45pseudouridine synthesis (GO:0001522)3.52343849
46spliceosomal complex assembly (GO:0000245)3.52106917
47negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436)3.51937616
48anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process (GO:03.51631853
49telomere maintenance via telomere lengthening (GO:0010833)3.50149958
50mitotic nuclear envelope disassembly (GO:0007077)3.49278371
51transcription elongation from RNA polymerase III promoter (GO:0006385)3.46814081
52termination of RNA polymerase III transcription (GO:0006386)3.46814081
53IMP biosynthetic process (GO:0006188)3.46293555
54regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051439)3.44660746
55cellular protein complex disassembly (GO:0043624)3.43197615
56nucleotide-excision repair, DNA gap filling (GO:0006297)3.43140176
57viral life cycle (GO:0019058)3.43127009
58establishment of protein localization to endoplasmic reticulum (GO:0072599)3.42264100
59protein localization to endoplasmic reticulum (GO:0070972)3.41998955
60positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051437)3.40447813
61peptidyl-arginine omega-N-methylation (GO:0035247)3.40328941
62DNA replication-independent nucleosome assembly (GO:0006336)3.34223399
63DNA replication-independent nucleosome organization (GO:0034724)3.34223399
64deoxyribonucleoside monophosphate metabolic process (GO:0009162)3.33848250
65metaphase plate congression (GO:0051310)3.32128857
66somatic diversification of immune receptors via somatic mutation (GO:0002566)3.30841098
67somatic hypermutation of immunoglobulin genes (GO:0016446)3.30841098
68translation (GO:0006412)3.25060528
69protein localization to chromosome, centromeric region (GO:0071459)3.24837549
70L-serine metabolic process (GO:0006563)3.24327326
71mitochondrial RNA metabolic process (GO:0000959)3.23488704
72transcription-coupled nucleotide-excision repair (GO:0006283)3.22103210
73negative regulation of ligase activity (GO:0051352)3.22069412
74negative regulation of ubiquitin-protein transferase activity (GO:0051444)3.22069412
75nuclear envelope disassembly (GO:0051081)3.20236308
76membrane disassembly (GO:0030397)3.20236308
77sister chromatid segregation (GO:0000819)3.18749323
78kinetochore organization (GO:0051383)3.18581774
79mitotic chromosome condensation (GO:0007076)3.17707605
80kinetochore assembly (GO:0051382)3.17693735
81folic acid metabolic process (GO:0046655)3.17541521
82IMP metabolic process (GO:0046040)3.17389894
83protein complex disassembly (GO:0043241)3.16346136
84rRNA modification (GO:0000154)3.15660548
85establishment of protein localization to mitochondrial membrane (GO:0090151)3.14862001
86negative regulation of chromosome segregation (GO:0051985)3.14825866
87base-excision repair (GO:0006284)3.14806370
88tRNA aminoacylation for protein translation (GO:0006418)3.14327669
89histone arginine methylation (GO:0034969)3.13088308
90pyrimidine nucleoside triphosphate biosynthetic process (GO:0009148)3.11685321
91negative regulation of mitotic sister chromatid separation (GO:2000816)3.11429440
92negative regulation of mitotic sister chromatid segregation (GO:0033048)3.11429440
93negative regulation of mitotic metaphase/anaphase transition (GO:0045841)3.11429440
94negative regulation of sister chromatid segregation (GO:0033046)3.11429440
95exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay 3.09469710
96tRNA aminoacylation (GO:0043039)3.09168295
97amino acid activation (GO:0043038)3.09168295
98negative regulation of mRNA processing (GO:0050686)3.09034988
99mitotic spindle assembly checkpoint (GO:0007094)3.08313734
100positive regulation of ubiquitin-protein transferase activity (GO:0051443)3.06566118
101regulation of translational fidelity (GO:0006450)3.06406195
102spindle assembly checkpoint (GO:0071173)3.05996838
103cellular component biogenesis (GO:0044085)3.05611373
104nuclear-transcribed mRNA catabolic process (GO:0000956)3.05298359
105histone exchange (GO:0043486)3.04767436
106spindle checkpoint (GO:0031577)3.03370157
107negative regulation of metaphase/anaphase transition of cell cycle (GO:1902100)3.03241069
108protein targeting to mitochondrion (GO:0006626)3.02907265
109regulation of cellular amino acid metabolic process (GO:0006521)3.02824898
110macromolecular complex disassembly (GO:0032984)3.02786171
111nuclear pore complex assembly (GO:0051292)3.02567743
112cell cycle G1/S phase transition (GO:0044843)3.01481190
113G1/S transition of mitotic cell cycle (GO:0000082)3.01481190
114RNA splicing, via transesterification reactions (GO:0000375)3.00712393
115mRNA splicing, via spliceosome (GO:0000398)2.99714393
116RNA splicing, via transesterification reactions with bulged adenosine as nucleophile (GO:0000377)2.99714393
117nucleobase-containing small molecule interconversion (GO:0015949)2.99408335
118pyrimidine nucleoside triphosphate metabolic process (GO:0009147)2.99327133
119positive regulation of ligase activity (GO:0051351)2.99195538
120mitotic spindle checkpoint (GO:0071174)2.99175987
121DNA damage response, detection of DNA damage (GO:0042769)2.98367044
122signal transduction involved in mitotic DNA integrity checkpoint (GO:1902403)2.98173873
123signal transduction involved in mitotic DNA damage checkpoint (GO:1902402)2.98173873
124signal transduction involved in mitotic cell cycle checkpoint (GO:0072413)2.98173873
1257-methylguanosine mRNA capping (GO:0006370)2.97080382
126peptidyl-arginine methylation (GO:0018216)2.97075928
127peptidyl-arginine N-methylation (GO:0035246)2.97075928
128pyrimidine deoxyribonucleotide catabolic process (GO:0009223)2.96658673
129regulation of ubiquitin-protein transferase activity (GO:0051438)2.96084874
130regulation of double-strand break repair via homologous recombination (GO:0010569)2.95841350
131negative regulation of mRNA splicing, via spliceosome (GO:0048025)2.95557966
132intracellular signal transduction involved in G1 DNA damage checkpoint (GO:1902400)2.95328563
133signal transduction involved in mitotic G1 DNA damage checkpoint (GO:0072431)2.95328563
134establishment of integrated proviral latency (GO:0075713)2.95188498
135DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest (GO:002.95096773
136signal transduction involved in DNA damage checkpoint (GO:0072422)2.94421018
137signal transduction involved in DNA integrity checkpoint (GO:0072401)2.94421018
138attachment of spindle microtubules to kinetochore (GO:0008608)2.93329313
139nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291)2.93066764
140regulation of attachment of spindle microtubules to kinetochore (GO:0051988)2.92984681

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1E2F7_22180533_ChIP-Seq_HELA_Human7.19484728
2MYC_18555785_ChIP-Seq_MESCs_Mouse4.47759172
3* EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse3.88319504
4FOXM1_23109430_ChIP-Seq_U2OS_Human3.36475997
5KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human3.27763172
6E2F4_17652178_ChIP-ChIP_JURKAT_Human3.23388212
7* JARID1A_20064375_ChIP-Seq_MESCs_Mouse3.13652979
8EST1_17652178_ChIP-ChIP_JURKAT_Human3.10108766
9ETS1_20019798_ChIP-Seq_JURKAT_Human3.09962603
10MYC_19079543_ChIP-ChIP_MESCs_Mouse3.09766902
11GABP_17652178_ChIP-ChIP_JURKAT_Human3.06843896
12MYC_18358816_ChIP-ChIP_MESCs_Mouse3.04384897
13MYC_19030024_ChIP-ChIP_MESCs_Mouse2.94806318
14FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human2.93808483
15CREB1_15753290_ChIP-ChIP_HEK293T_Human2.83995692
16HCFC1_20581084_ChIP-Seq_MESCs_Mouse2.67070590
17XRN2_22483619_ChIP-Seq_HELA_Human2.52954829
18E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse2.38199848
19NELFA_20434984_ChIP-Seq_ESCs_Mouse2.38100623
20NOTCH1_17114293_ChIP-ChIP_T-ALL_Human2.33423699
21CHD1_19587682_ChIP-ChIP_MESCs_Mouse2.31687462
22* VDR_23849224_ChIP-Seq_CD4+_Human2.29759447
23* E2F1_18555785_ChIP-Seq_MESCs_Mouse2.16003223
24MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse2.14279805
25DCP1A_22483619_ChIP-Seq_HELA_Human2.11056858
26* GABP_19822575_ChIP-Seq_HepG2_Human2.07842863
27ELF1_17652178_ChIP-ChIP_JURKAT_Human2.03300308
28FOXP3_21729870_ChIP-Seq_TREG_Human2.02158424
29HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human1.96703325
30THAP11_20581084_ChIP-Seq_MESCs_Mouse1.95972922
31TTF2_22483619_ChIP-Seq_HELA_Human1.93978766
32MYCN_18555785_ChIP-Seq_MESCs_Mouse1.92196564
33MYBL2_22936984_ChIP-ChIP_MESCs_Mouse1.87996949
34AR_21909140_ChIP-Seq_LNCAP_Human1.82593073
35POU5F1_18555785_ChIP-Seq_MESCs_Mouse1.80811851
36NANOG_18555785_ChIP-Seq_MESCs_Mouse1.80288122
37E2F1_21310950_ChIP-Seq_MCF-7_Human1.76848416
38PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse1.74177967
39* ZFX_18555785_ChIP-Seq_MESCs_Mouse1.74153780
40YY1_21170310_ChIP-Seq_MESCs_Mouse1.72108284
41SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse1.71274022
42SOX9_22984422_ChIP-ChIP_TESTIS_Rat1.70122582
43CIITA_25753668_ChIP-Seq_RAJI_Human1.68372914
44TAL1_20887958_ChIP-Seq_HPC-7_Mouse1.67308063
45FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse1.63034298
46ZFP42_18358816_ChIP-ChIP_MESCs_Mouse1.60642150
47YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.56303290
48KDM5A_27292631_Chip-Seq_BREAST_Human1.54275091
49MYC_22102868_ChIP-Seq_BL_Human1.50877062
50SRF_21415370_ChIP-Seq_HL-1_Mouse1.46245733
51CCND1_20090754_ChIP-ChIP_RETINA_Mouse1.46149804
52CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human1.46002226
53ELK1_19687146_ChIP-ChIP_HELA_Human1.43058986
54HOXB4_20404135_ChIP-ChIP_EML_Mouse1.39385102
55TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat1.38718989
56CEBPB_23403033_ChIP-Seq_LIVER_Mouse1.37656378
57POU5F1_18700969_ChIP-ChIP_MESCs_Mouse1.35166812
58* KDM5B_21448134_ChIP-Seq_MESCs_Mouse1.34275262
59SFPI1_20887958_ChIP-Seq_HPC-7_Mouse1.33154085
60DACH1_20351289_ChIP-Seq_MDA-MB-231_Human1.32017240
61KLF4_18555785_ChIP-Seq_MESCs_Mouse1.30877879
62FLI1_20887958_ChIP-Seq_HPC-7_Mouse1.29696474
63SMAD1_18555785_ChIP-Seq_MESCs_Mouse1.29206017
64STAT3_1855785_ChIP-Seq_MESCs_Mouse1.29199514
65ERG_20887958_ChIP-Seq_HPC-7_Mouse1.28167055
66MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.26633958
67POU5F1_18358816_ChIP-ChIP_MESCs_Mouse1.26319900
68CNOT3_19339689_ChIP-ChIP_MESCs_Mouse1.19171952
69KLF4_19030024_ChIP-ChIP_MESCs_Mouse1.18053662
70E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human1.15670078
71PDX1_19855005_ChIP-ChIP_MIN6_Mouse1.15144316
72BCL3_23251550_ChIP-Seq_MUSCLE_Mouse1.12510820
73SOX2_18555785_ChIP-Seq_MESCs_Mouse1.08285429
74CEBPA_23403033_ChIP-Seq_LIVER_Mouse1.06203171
75ESR1_15608294_ChIP-ChIP_MCF-7_Human1.05304231
76ASXL1_24218140_ChIP-Seq_BMDM_Mouse1.04393318
77EGR1_19374776_ChIP-ChIP_THP-1_Human1.04198432
78TFEB_21752829_ChIP-Seq_HELA_Human1.03786542
79KLF4_18358816_ChIP-ChIP_MESCs_Mouse1.03693145
80NOTCH1_21737748_ChIP-Seq_TLL_Human1.03583310
81PADI4_21655091_ChIP-ChIP_MCF-7_Human1.02825592
82RBPJ_22232070_ChIP-Seq_NCS_Mouse1.02553305
83TP63_19390658_ChIP-ChIP_HaCaT_Human1.02123507
84VDR_21846776_ChIP-Seq_THP-1_Human1.01718397
85CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat1.00864201
86CEBPB_24764292_ChIP-Seq_MC3T3_Mouse1.00855722
87* CREM_20920259_ChIP-Seq_GC1-SPG_Mouse1.00676521
88PRDM5_23873026_ChIP-Seq_MEFs_Mouse1.00287905
89* MYC_18940864_ChIP-ChIP_HL60_Human0.98804137
90TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse0.96108239
91ELK1_22589737_ChIP-Seq_MCF10A_Human0.96100096
92ASH2L_23239880_ChIP-Seq_MESCs_Mouse0.95380448
93HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse0.94916439
94GFI1B_20887958_ChIP-Seq_HPC-7_Mouse0.93983979
95ZNF263_19887448_ChIP-Seq_K562_Human0.92869695
96HSF1_23293686_ChIP-Seq_STHDH_STRIATAL_Mouse0.90455093
97CREB1_20920259_ChIP-Seq_GC1-SPG_Mouse0.89648493
98FOXP1_21924763_ChIP-Seq_HESCs_Human0.89545514
99ESRRB_18555785_ChIP-Seq_MESCs_Mouse0.89150650
100SIN3A_21632747_ChIP-Seq_MESCs_Mouse0.89053804
101NANOG_16153702_ChIP-ChIP_HESCs_Human0.88367835
102ZFP281_18358816_ChIP-ChIP_MESCs_Mouse0.88009204
103SRY_22984422_ChIP-ChIP_TESTIS_Rat0.87057213
104TCF3_18692474_ChIP-Seq_MEFs_Mouse0.86696296
105OCT4_18692474_ChIP-Seq_MEFs_Mouse0.86417838
106TBX5_21415370_ChIP-Seq_HL-1_Mouse0.86386488
107SOX2_18692474_ChIP-Seq_MEFs_Mouse0.85564836
108PPARG_19300518_ChIP-PET_3T3-L1_Mouse0.84572165
109SOX2_16153702_ChIP-ChIP_HESCs_Human0.84301505
110DMRT1_21621532_ChIP-ChIP_FETAL_Ovary0.84184734
111SOX17_20123909_ChIP-Seq_XEN_Mouse0.84138009
112TRIM28_19339689_ChIP-ChIP_MESCs_Mouse0.83864813
113SPI1_22096565_ChIP-ChIP_GC-B_Mouse0.83487368
114HNF4A_19761587_ChIP-ChIP_CACO-2_Human0.81988466
115NANOG_21062744_ChIP-ChIP_HESCs_Human0.81745010
116CUX1_19635798_ChIP-ChIP_MULTIPLE_HUMAN_CANCER_TYPES_Human0.77680514

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0003693_abnormal_embryo_hatching5.85292267
2MP0003111_abnormal_nucleus_morphology4.76445860
3MP0004957_abnormal_blastocyst_morpholog4.75215670
4MP0010094_abnormal_chromosome_stability4.62844775
5MP0003077_abnormal_cell_cycle4.19999074
6MP0008057_abnormal_DNA_replication3.54280635
7MP0008058_abnormal_DNA_repair3.25386502
8MP0008932_abnormal_embryonic_tissue3.06102208
9MP0008007_abnormal_cellular_replicative2.97728208
10MP0003123_paternal_imprinting2.86401371
11MP0001730_embryonic_growth_arrest2.48909798
12MP0000350_abnormal_cell_proliferation2.22298501
13MP0003786_premature_aging2.19036806
14MP0008877_abnormal_DNA_methylation2.11767379
15MP0003718_maternal_effect2.10321906
16MP0002396_abnormal_hematopoietic_system2.03696506
17MP0001697_abnormal_embryo_size1.88714604
18MP0001672_abnormal_embryogenesis/_devel1.80824197
19MP0005380_embryogenesis_phenotype1.80824197
20MP0002080_prenatal_lethality1.76339563
21MP0002085_abnormal_embryonic_tissue1.67166030
22MP0000490_abnormal_crypts_of1.65717667
23MP0009697_abnormal_copulation1.64537889
24MP0003315_abnormal_perineum_morphology1.63401445
25MP0003984_embryonic_growth_retardation1.57519084
26MP0003806_abnormal_nucleotide_metabolis1.55264552
27MP0000313_abnormal_cell_death1.55167727
28MP0002088_abnormal_embryonic_growth/wei1.53936355
29MP0003567_abnormal_fetal_cardiomyocyte1.52425635
30MP0002084_abnormal_developmental_patter1.51862999
31MP0010030_abnormal_orbit_morphology1.49785290
32MP0000566_synostosis1.49781535
33MP0010352_gastrointestinal_tract_polyps1.48286346
34MP0010307_abnormal_tumor_latency1.42785911
35MP0002019_abnormal_tumor_incidence1.42253624
36MP0001293_anophthalmia1.41774526
37MP0001529_abnormal_vocalization1.40674314
38MP0006292_abnormal_olfactory_placode1.40327725
39MP0008789_abnormal_olfactory_epithelium1.40266362
40MP0002210_abnormal_sex_determination1.39633163
41MP0003119_abnormal_digestive_system1.35477349
42MP0009333_abnormal_splenocyte_physiolog1.34910599
43MP0002086_abnormal_extraembryonic_tissu1.31521716
44MP0004147_increased_porphyrin_level1.29714980
45MP0005394_taste/olfaction_phenotype1.29167756
46MP0005499_abnormal_olfactory_system1.29167756
47MP0000358_abnormal_cell_content/1.28790923
48MP0001145_abnormal_male_reproductive1.27704875
49MP0004808_abnormal_hematopoietic_stem1.27520660
50MP0004197_abnormal_fetal_growth/weight/1.23830966
51MP0002160_abnormal_reproductive_system1.21428959
52MP0004133_heterotaxia1.21029377
53MP0002653_abnormal_ependyma_morphology1.19277070
54MP0000579_abnormal_nail_morphology1.19095332
55MP0001346_abnormal_lacrimal_gland1.17949346
56MP0000372_irregular_coat_pigmentation1.16242259
57MP0002234_abnormal_pharynx_morphology1.15797526
58MP0005501_abnormal_skin_physiology1.14269069
59MP0009379_abnormal_foot_pigmentation1.10195444
60MP0001929_abnormal_gametogenesis1.08372152
61MP0000537_abnormal_urethra_morphology1.08127278
62MP0009672_abnormal_birth_weight1.07685287
63MP0005075_abnormal_melanosome_morpholog1.07254081
64MP0000653_abnormal_sex_gland1.06557869
65MP0005397_hematopoietic_system_phenotyp1.06091041
66MP0001545_abnormal_hematopoietic_system1.06091041
67MP0009053_abnormal_anal_canal1.06042305
68MP0003890_abnormal_embryonic-extraembry1.06023250
69MP0006035_abnormal_mitochondrial_morpho1.04753718
70MP0003121_genomic_imprinting1.04725921
71MP0006036_abnormal_mitochondrial_physio1.03312155
72MP0003186_abnormal_redox_activity1.03060668
73MP0002697_abnormal_eye_size1.02179834
74MP0003221_abnormal_cardiomyocyte_apopto0.96449012
75MP0000703_abnormal_thymus_morphology0.95907481
76MP0002796_impaired_skin_barrier0.93393582
77MP0005389_reproductive_system_phenotype0.90863393
78MP0001188_hyperpigmentation0.90266866
79MP0002722_abnormal_immune_system0.85665949
80MP0001661_extended_life_span0.83625379
81MP0004185_abnormal_adipocyte_glucose0.83226134
82MP0001119_abnormal_female_reproductive0.82159767
83MP0002111_abnormal_tail_morphology0.81994342
84MP0000689_abnormal_spleen_morphology0.81964080
85MP0003763_abnormal_thymus_physiology0.81004748
86MP0003937_abnormal_limbs/digits/tail_de0.80981629
87MP0002132_abnormal_respiratory_system0.80707129
88MP0002938_white_spotting0.80699930
89MP0005384_cellular_phenotype0.80510088
90MP0002102_abnormal_ear_morphology0.80199665
91MP0009840_abnormal_foam_cell0.79864540
92MP0002398_abnormal_bone_marrow0.77802028
93MP0002233_abnormal_nose_morphology0.76401155
94MP0000647_abnormal_sebaceous_gland0.75554688
95MP0000428_abnormal_craniofacial_morphol0.74724874
96MP0002751_abnormal_autonomic_nervous0.74024827
97MP0002092_abnormal_eye_morphology0.70738793
98MP0001286_abnormal_eye_development0.69573954
99MP0004233_abnormal_muscle_weight0.69564776
100MP0008260_abnormal_autophagy0.67708821
101MP0000762_abnormal_tongue_morphology0.67580683
102MP0002163_abnormal_gland_morphology0.67426854
103MP0000477_abnormal_intestine_morphology0.66546859
104MP0008995_early_reproductive_senescence0.65707676
105MP0002822_catalepsy0.65249711
106MP0006072_abnormal_retinal_apoptosis0.65192994
107MP0005621_abnormal_cell_physiology0.64302950
108MP0002429_abnormal_blood_cell0.64041506
109MP0002736_abnormal_nociception_after0.63664575
110MP0000467_abnormal_esophagus_morphology0.61658362
111MP0000678_abnormal_parathyroid_gland0.61014905
112MP0001727_abnormal_embryo_implantation0.60720691
113MP0000049_abnormal_middle_ear0.60499779
114MP0002877_abnormal_melanocyte_morpholog0.60487429
115MP0009703_decreased_birth_body0.59994370
116MP0001849_ear_inflammation0.58857324
117MP0005174_abnormal_tail_pigmentation0.58584014
118MP0001915_intracranial_hemorrhage0.58104165
119MP0001919_abnormal_reproductive_system0.56515259
120MP0003941_abnormal_skin_development0.56469740
121MP0003699_abnormal_female_reproductive0.55448853
122MP0003938_abnormal_ear_development0.54737546
123MP0001764_abnormal_homeostasis0.53776809
124MP0002161_abnormal_fertility/fecundity0.53747660
125MP0005266_abnormal_metabolism0.52034097
126MP0003698_abnormal_male_reproductive0.51707060
127MP0003861_abnormal_nervous_system0.51371052
128MP0005395_other_phenotype0.50590347

Predicted human phenotypes

RankGene SetZ-score
1Abnormality of cells of the erythroid lineage (HP:0012130)4.96047057
2Reticulocytopenia (HP:0001896)4.95636462
3Abnormal number of erythroid precursors (HP:0012131)4.79514466
4Birth length less than 3rd percentile (HP:0003561)4.62511842
5Breast hypoplasia (HP:0003187)4.38204883
6Cerebral hypomyelination (HP:0006808)3.76029605
7Macrocytic anemia (HP:0001972)3.69543063
8Patellar aplasia (HP:0006443)3.67903200
9Oral leukoplakia (HP:0002745)3.60304784
10Aplasia/Hypoplasia of the patella (HP:0006498)3.59272774
11Carpal bone hypoplasia (HP:0001498)3.58535697
12Colon cancer (HP:0003003)3.52666439
13Abnormal mitochondria in muscle tissue (HP:0008316)3.41414461
14Acute necrotizing encephalopathy (HP:0006965)3.35613169
15Selective tooth agenesis (HP:0001592)3.34067834
16Acute encephalopathy (HP:0006846)3.23882479
17Abnormality of the anterior horn cell (HP:0006802)3.23459123
18Degeneration of anterior horn cells (HP:0002398)3.23459123
19Pallor (HP:0000980)3.21804798
20Aplastic anemia (HP:0001915)3.21624518
21Rough bone trabeculation (HP:0100670)3.14133543
22Increased CSF lactate (HP:0002490)3.09964246
23Mitochondrial inheritance (HP:0001427)3.06939181
24Ependymoma (HP:0002888)3.02223085
25Microretrognathia (HP:0000308)2.98280901
26Abnormality of glycolysis (HP:0004366)2.95709425
27Progressive muscle weakness (HP:0003323)2.86076428
28Absent radius (HP:0003974)2.83078875
29Increased serum pyruvate (HP:0003542)2.79468476
30Multiple enchondromatosis (HP:0005701)2.77369473
31Absent thumb (HP:0009777)2.76627849
32Aplasia/Hypoplasia of the sacrum (HP:0008517)2.72819405
33Cerebral edema (HP:0002181)2.72191295
34Meckel diverticulum (HP:0002245)2.67541585
35Medulloblastoma (HP:0002885)2.67346602
36Premature ovarian failure (HP:0008209)2.65903468
37Aplasia/Hypoplasia involving the carpal bones (HP:0006502)2.65204147
38Neoplasm of the pancreas (HP:0002894)2.65077372
39CNS hypomyelination (HP:0003429)2.64705234
40Absent forearm bone (HP:0003953)2.60606438
41Aplasia involving forearm bones (HP:0009822)2.60606438
42Lactic acidosis (HP:0003128)2.58721397
43Secondary amenorrhea (HP:0000869)2.57602394
44Abnormality of the ileum (HP:0001549)2.56362648
45Trismus (HP:0000211)2.52936700
46Abnormal activity of mitochondrial respiratory chain (HP:0011922)2.52750703
47Decreased activity of mitochondrial respiratory chain (HP:0008972)2.52750703
48Horseshoe kidney (HP:0000085)2.52165968
49Premature graying of hair (HP:0002216)2.49434266
50Rhabdomyosarcoma (HP:0002859)2.48661257
51Abnormal protein glycosylation (HP:0012346)2.45843284
52Abnormal glycosylation (HP:0012345)2.45843284
53Abnormal isoelectric focusing of serum transferrin (HP:0003160)2.45843284
54Abnormal protein N-linked glycosylation (HP:0012347)2.45843284
55Impulsivity (HP:0100710)2.44473304
56Progressive macrocephaly (HP:0004481)2.43370438
57Abnormality of chromosome stability (HP:0003220)2.42923910
58Increased hepatocellular lipid droplets (HP:0006565)2.42679559
59Chromsome breakage (HP:0040012)2.42059192
60Abnormality of the preputium (HP:0100587)2.40628127
61Abnormal number of incisors (HP:0011064)2.36033189
62Increased serum lactate (HP:0002151)2.35574164
63Increased intramyocellular lipid droplets (HP:0012240)2.34346497
6411 pairs of ribs (HP:0000878)2.32266062
65Chromosomal breakage induced by crosslinking agents (HP:0003221)2.31473515
66Reduced antithrombin III activity (HP:0001976)2.30672414
67Lipid accumulation in hepatocytes (HP:0006561)2.26581973
683-Methylglutaconic aciduria (HP:0003535)2.25688424
69Cellular immunodeficiency (HP:0005374)2.25342283
70Abnormal trabecular bone morphology (HP:0100671)2.25071257
71Facial cleft (HP:0002006)2.23775155
72Triphalangeal thumb (HP:0001199)2.21842792
73Exercise intolerance (HP:0003546)2.20749464
74Abnormal gallbladder physiology (HP:0012438)2.19547890
75Cholecystitis (HP:0001082)2.19547890
76Megaloblastic anemia (HP:0001889)2.18747970
77Agnosia (HP:0010524)2.16823748
78Atrophy/Degeneration involving motor neurons (HP:0007373)2.16580698
79Bone marrow hypocellularity (HP:0005528)2.15904190
80Supernumerary spleens (HP:0009799)2.15734175
81Myelodysplasia (HP:0002863)2.13321494
82Aplasia/Hypoplasia of the uvula (HP:0010293)2.13094838
83Hyperglycinemia (HP:0002154)2.11046652
84Atresia of the external auditory canal (HP:0000413)2.08094239
85Basal cell carcinoma (HP:0002671)2.07321009
86Pancytopenia (HP:0001876)2.06871645
87Hepatocellular necrosis (HP:0001404)2.06530013
88Small intestinal stenosis (HP:0012848)2.04525260
89Duodenal stenosis (HP:0100867)2.04525260
90Abnormality of the carotid arteries (HP:0005344)2.04349073
91Abnormality of serum amino acid levels (HP:0003112)2.03844850
92Type I transferrin isoform profile (HP:0003642)2.01517506
93Microvesicular hepatic steatosis (HP:0001414)2.00345619
94Abnormality of pyruvate family amino acid metabolism (HP:0010915)2.00096393
95Abnormality of alanine metabolism (HP:0010916)2.00096393
96Hyperalaninemia (HP:0003348)2.00096393
97Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688)1.99896876
98Nephroblastoma (Wilms tumor) (HP:0002667)1.97450961
99Sparse eyelashes (HP:0000653)1.96920255
100Abnormality of the labia minora (HP:0012880)1.96306458
101Postnatal microcephaly (HP:0005484)1.96302646
102Cleft eyelid (HP:0000625)1.95460470
103Abnormal lung lobation (HP:0002101)1.95023814
104Tracheoesophageal fistula (HP:0002575)1.93383284
105Increased muscle lipid content (HP:0009058)1.92199385
106Facial hemangioma (HP:0000329)1.92098411
107Hypoplasia of the radius (HP:0002984)1.91551040
108Muscle fiber atrophy (HP:0100295)1.90737455
109Hepatic necrosis (HP:0002605)1.90196164
110Thrombocytosis (HP:0001894)1.89108368
111Abnormality of the fetal cardiovascular system (HP:0010948)1.88356382
112Abnormal umbilical cord blood vessels (HP:0011403)1.88356382
113Single umbilical artery (HP:0001195)1.88356382
114Squamous cell carcinoma (HP:0002860)1.87939059
115Muscle abnormality related to mitochondrial dysfunction (HP:0003800)1.87393412
116Personality changes (HP:0000751)1.86705251
117Proximal placement of thumb (HP:0009623)1.86259701
118Broad distal phalanx of finger (HP:0009836)1.85344003
119Methylmalonic aciduria (HP:0012120)1.84448393
120Embryonal renal neoplasm (HP:0011794)1.83101638
121Abnormal spermatogenesis (HP:0008669)1.82272029
122Aplasia/Hypoplasia involving the musculature (HP:0001460)1.81834783
123Hypoplasia of the pons (HP:0012110)1.81356075
124Sloping forehead (HP:0000340)1.81333455
125Ragged-red muscle fibers (HP:0003200)1.81263020
126Neoplasm of striated muscle (HP:0009728)1.80700478
127IgM deficiency (HP:0002850)1.79842018
128Optic nerve coloboma (HP:0000588)1.79565714
129Glossoptosis (HP:0000162)1.79517172
130Aplasia/hypoplasia of the humerus (HP:0006507)1.79445611
131Abnormality of the duodenum (HP:0002246)1.79063073
132Slender long bone (HP:0003100)1.78959893
133Respiratory failure (HP:0002878)1.78850908
134Lymphoma (HP:0002665)1.78372681
135Increased nuchal translucency (HP:0010880)1.77804718
136Neoplasm of the adrenal gland (HP:0100631)1.76335595
137Abnormality of the umbilical cord (HP:0010881)1.76255220
138Abnormality of reticulocytes (HP:0004312)1.75717402
139High anterior hairline (HP:0009890)1.75574084
140Abnormality of abdominal situs (HP:0011620)1.74806032

Predicted kinase interactions (KEA)

RankGene SetZ-score
1BUB15.71153914
2VRK24.66205451
3WEE14.64645365
4EIF2AK13.53143143
5CDC73.31737070
6SRPK12.88323575
7TLK12.85364269
8STK162.81217893
9PBK2.64941749
10NEK22.47947870
11PLK42.36205032
12NME22.30708087
13TESK22.15058550
14TTK2.14302124
15DYRK32.13096997
16TSSK62.07256446
17ACVR1B1.99894630
18PLK11.92447394
19CDK71.81615173
20NEK11.76321959
21BRSK21.75635798
22TRIM281.73658132
23VRK11.72565582
24SMG11.57612341
25EPHA21.56587581
26MKNK11.54761844
27EIF2AK31.50266405
28AURKB1.49702475
29RPS6KB21.47318710
30AURKA1.43382762
31CHEK21.43371822
32SCYL21.42669610
33PASK1.41033305
34ATR1.39221095
35RPS6KA41.37203169
36MAP3K81.31667074
37BCKDK1.31230857
38MAP3K111.30990749
39MAP3K101.29162907
40CDK41.25935024
41MKNK21.24926535
42KDR1.23903496
43PLK31.22701293
44MST41.21530641
45TAF11.20195238
46BRSK11.14783873
47BRAF1.14417136
48PDK21.13470351
49TGFBR11.08177940
50PIM21.07444183
51NUAK11.06665716
52ZAK1.03258042
53DAPK11.02496447
54CHEK11.02262227
55NME10.93407471
56PAK40.86802557
57EEF2K0.85857872
58CDK80.84715819
59PIM10.83335559
60DYRK20.83021782
61PAK10.78157217
62CDK20.77414578
63FLT30.76788770
64MAP4K20.74689884
65CSNK2A20.73568940
66CCNB10.73215812
67CSNK2A10.72056844
68LATS20.71095960
69MAP2K70.67919594
70STK100.66459292
71STK40.64717509
72ATM0.64339682
73CSNK1A1L0.64302709
74PRKCI0.61530073
75AKT30.61472447
76LRRK20.60936893
77STK38L0.59418049
78ILK0.59389918
79MST1R0.58786414
80BRD40.58552736
81RPS6KA50.58530497
82PNCK0.58084391
83CDK120.57953015
84CLK10.57678125
85CSNK1G20.55898503
86MAP4K10.55203925
87CDK90.52792319
88ERBB40.52180327
89CDK10.50811759
90EIF2AK20.46385262
91RAF10.45289934
92CDK190.44890474
93TESK10.44853858
94CDK180.41405190
95CSNK1E0.40313987
96CDK11A0.40106874
97MAPKAPK30.39978458
98TAOK20.39033614
99MELK0.38456480
100WNK30.38324320
101BCR0.38180148
102CSNK1G30.38131432
103CDK150.38046785
104MAP2K30.36275880
105AKT20.36138413
106CDK140.34476628
107ALK0.33074083
108MAPKAPK50.33016922
109DAPK30.31024347
110ABL20.29928800
111DYRK1B0.29210122
112MTOR0.27608552
113BTK0.26847489
114MAPK110.26257207
115MAP3K120.26059304
116MINK10.25305672
117CSNK1G10.25007120
118CDK60.24539732
119IRAK30.23115159
120MAP2K20.22867850
121LIMK10.21337562
122MAP3K50.20819564
123PRKDC0.20054438
124ARAF0.18949865
125RPS6KA10.15930680
126PAK20.15515776

Predicted pathways (KEGG)

RankGene SetZ-score
1DNA replication_Homo sapiens_hsa030304.92890031
2Ribosome_Homo sapiens_hsa030104.14714082
3Mismatch repair_Homo sapiens_hsa034304.05573400
4RNA polymerase_Homo sapiens_hsa030203.73375476
5Proteasome_Homo sapiens_hsa030503.66775623
6Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030083.57773564
7* Spliceosome_Homo sapiens_hsa030403.43216576
8Base excision repair_Homo sapiens_hsa034103.12342673
9* RNA transport_Homo sapiens_hsa030133.03279942
10Homologous recombination_Homo sapiens_hsa034402.95470727
11Nucleotide excision repair_Homo sapiens_hsa034202.73060294
12Pyrimidine metabolism_Homo sapiens_hsa002402.72148906
13Cell cycle_Homo sapiens_hsa041102.56559343
14One carbon pool by folate_Homo sapiens_hsa006702.46027797
15Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009702.19467906
16Fanconi anemia pathway_Homo sapiens_hsa034602.02024522
17RNA degradation_Homo sapiens_hsa030181.82266823
18Basal transcription factors_Homo sapiens_hsa030221.78752948
19Folate biosynthesis_Homo sapiens_hsa007901.66808401
20mRNA surveillance pathway_Homo sapiens_hsa030151.56821467
21Sulfur relay system_Homo sapiens_hsa041221.48955901
22Non-homologous end-joining_Homo sapiens_hsa034501.44965905
23p53 signaling pathway_Homo sapiens_hsa041151.44934421
24Purine metabolism_Homo sapiens_hsa002301.44577361
25Fatty acid elongation_Homo sapiens_hsa000621.39714975
26Vitamin B6 metabolism_Homo sapiens_hsa007501.21411747
27Cysteine and methionine metabolism_Homo sapiens_hsa002701.14614461
28Systemic lupus erythematosus_Homo sapiens_hsa053221.13871175
29Epstein-Barr virus infection_Homo sapiens_hsa051691.13032111
30Pentose phosphate pathway_Homo sapiens_hsa000301.11501475
31Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004001.10230480
32Protein export_Homo sapiens_hsa030601.04297456
33Ubiquitin mediated proteolysis_Homo sapiens_hsa041201.02675902
34Cytosolic DNA-sensing pathway_Homo sapiens_hsa046231.01759945
35Biosynthesis of amino acids_Homo sapiens_hsa012301.00945048
36Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005201.00590334
37Propanoate metabolism_Homo sapiens_hsa006400.97857063
38Oocyte meiosis_Homo sapiens_hsa041140.97298684
39Drug metabolism - other enzymes_Homo sapiens_hsa009830.93225579
40Selenocompound metabolism_Homo sapiens_hsa004500.89338373
41Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.88236133
42Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.87591196
43Huntingtons disease_Homo sapiens_hsa050160.85204452
44Cyanoamino acid metabolism_Homo sapiens_hsa004600.84993211
45Valine, leucine and isoleucine degradation_Homo sapiens_hsa002800.84700878
46Steroid biosynthesis_Homo sapiens_hsa001000.84271386
47Parkinsons disease_Homo sapiens_hsa050120.80559286
48Viral carcinogenesis_Homo sapiens_hsa052030.75718799
49Thyroid cancer_Homo sapiens_hsa052160.67303859
50Carbon metabolism_Homo sapiens_hsa012000.66442089
51Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006300.66131237
52Herpes simplex infection_Homo sapiens_hsa051680.64243644
53Sulfur metabolism_Homo sapiens_hsa009200.63367535
54Glutathione metabolism_Homo sapiens_hsa004800.62907107
55Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.60890185
56Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.60585822
57Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010400.60120153
58Synthesis and degradation of ketone bodies_Homo sapiens_hsa000720.59894820
59Antigen processing and presentation_Homo sapiens_hsa046120.56805893
60Oxidative phosphorylation_Homo sapiens_hsa001900.55315734
61HTLV-I infection_Homo sapiens_hsa051660.54629065
62Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001300.51857563
632-Oxocarboxylic acid metabolism_Homo sapiens_hsa012100.51764992
64N-Glycan biosynthesis_Homo sapiens_hsa005100.48448203
65Citrate cycle (TCA cycle)_Homo sapiens_hsa000200.48283729
66Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.48141889
67Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.47999284
68Fructose and mannose metabolism_Homo sapiens_hsa000510.42597391
69Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.41188107
70Alcoholism_Homo sapiens_hsa050340.41061278
71Metabolic pathways_Homo sapiens_hsa011000.39953333
72Peroxisome_Homo sapiens_hsa041460.36696296
73Regulation of autophagy_Homo sapiens_hsa041400.35884354
74Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.35874924
75Basal cell carcinoma_Homo sapiens_hsa052170.35276723
76Arginine biosynthesis_Homo sapiens_hsa002200.35064969
77Cardiac muscle contraction_Homo sapiens_hsa042600.34113127
78Phenylalanine metabolism_Homo sapiens_hsa003600.34102196
79Fatty acid metabolism_Homo sapiens_hsa012120.34101142
80Small cell lung cancer_Homo sapiens_hsa052220.32958370
81Hippo signaling pathway_Homo sapiens_hsa043900.31603720
82Transcriptional misregulation in cancer_Homo sapiens_hsa052020.31121997
83Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049320.30334715
84Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.30120086
85Bladder cancer_Homo sapiens_hsa052190.28803939
86MicroRNAs in cancer_Homo sapiens_hsa052060.28525730
87Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.27235291
88Hedgehog signaling pathway_Homo sapiens_hsa043400.23892779
89Legionellosis_Homo sapiens_hsa051340.23847578
90Galactose metabolism_Homo sapiens_hsa000520.23074852
91Notch signaling pathway_Homo sapiens_hsa043300.22565310
92Colorectal cancer_Homo sapiens_hsa052100.22384032
93Butanoate metabolism_Homo sapiens_hsa006500.21861751
94Arginine and proline metabolism_Homo sapiens_hsa003300.21690689
95Lysine degradation_Homo sapiens_hsa003100.21417850
96Primary immunodeficiency_Homo sapiens_hsa053400.21074883
97Vibrio cholerae infection_Homo sapiens_hsa051100.20312345
98Tyrosine metabolism_Homo sapiens_hsa003500.19453094
99Pyruvate metabolism_Homo sapiens_hsa006200.19426793
100Apoptosis_Homo sapiens_hsa042100.19253627
101Shigellosis_Homo sapiens_hsa051310.18623376
102Pentose and glucuronate interconversions_Homo sapiens_hsa000400.18196640
103Acute myeloid leukemia_Homo sapiens_hsa052210.14423759
104TGF-beta signaling pathway_Homo sapiens_hsa043500.13326512
105Alzheimers disease_Homo sapiens_hsa050100.12416125
106Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.12160873
107Central carbon metabolism in cancer_Homo sapiens_hsa052300.10534147
108Pathways in cancer_Homo sapiens_hsa052000.10178334
109Phototransduction_Homo sapiens_hsa047440.09981312
110Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005340.09138338
111Hepatitis B_Homo sapiens_hsa051610.09072929
112Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.08059205
113HIF-1 signaling pathway_Homo sapiens_hsa040660.05751176
114beta-Alanine metabolism_Homo sapiens_hsa004100.04403194
115Wnt signaling pathway_Homo sapiens_hsa043100.04319506
116Chronic myeloid leukemia_Homo sapiens_hsa052200.03767316
117Arachidonic acid metabolism_Homo sapiens_hsa005900.01714529
118Measles_Homo sapiens_hsa051620.01240233
119Non-small cell lung cancer_Homo sapiens_hsa05223-0.0245573
120Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa00250-0.0228832
121Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa00533-0.0040357

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