TEX13A

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: This gene is similar to a mouse gene that is expressed in the testis. Alternative splicing results in multiple transcript variants. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1reproduction (GO:0000003)9.90554549
2epithelial cilium movement (GO:0003351)9.81825683
3spermatid development (GO:0007286)9.79265383
4axonemal dynein complex assembly (GO:0070286)9.70054067
5motile cilium assembly (GO:0044458)9.50190310
6cilium or flagellum-dependent cell motility (GO:0001539)9.05589036
7regulation of cilium movement (GO:0003352)8.46364805
8cilium movement (GO:0003341)7.86227976
9single fertilization (GO:0007338)7.64901711
10epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287)7.40174507
11negative regulation of inclusion body assembly (GO:0090084)7.08754419
12sperm capacitation (GO:0048240)7.07018488
13male meiosis (GO:0007140)6.87011091
14synaptonemal complex organization (GO:0070193)6.84668060
15piRNA metabolic process (GO:0034587)6.76684884
16microtubule depolymerization (GO:0007019)6.76679074
17synaptonemal complex assembly (GO:0007130)6.73287271
18spermatogenesis (GO:0007283)6.72271720
19male gamete generation (GO:0048232)6.69931011
20organic cation transport (GO:0015695)6.47524253
21fertilization (GO:0009566)6.40449324
22gamete generation (GO:0007276)6.15579010
23regulation of inclusion body assembly (GO:0090083)5.92388889
24calcium ion-dependent exocytosis (GO:0017156)5.72482351
25germ cell development (GO:0007281)5.39046602
26cellular process involved in reproduction in multicellular organism (GO:0022412)5.34935850
27spermatid nucleus differentiation (GO:0007289)5.31409855
28glycerol ether metabolic process (GO:0006662)5.30926902
29cell recognition (GO:0008037)5.14773394
30chromosome condensation (GO:0030261)5.11169020
31ventricular system development (GO:0021591)5.03235076
32regulation of microtubule-based movement (GO:0060632)4.99392071
33ether metabolic process (GO:0018904)4.90980888
34multicellular organismal reproductive process (GO:0048609)4.84569672
35DNA packaging (GO:0006323)4.79279397
36chromosome organization involved in meiosis (GO:0070192)4.60103602
37microtubule severing (GO:0051013)4.55831362
38male meiosis I (GO:0007141)4.51018708
39seminiferous tubule development (GO:0072520)4.39921677
40DNA methylation involved in gamete generation (GO:0043046)4.38963171
41sexual reproduction (GO:0019953)4.31675676
42chaperone-mediated protein complex assembly (GO:0051131)4.27298484
43left/right pattern formation (GO:0060972)4.07712799
44single strand break repair (GO:0000012)4.06553982
45meiotic nuclear division (GO:0007126)4.03537657
46multicellular organismal development (GO:0007275)3.91382565
47sequestering of actin monomers (GO:0042989)3.56402646
48meiosis I (GO:0007127)3.56337017
49protein K11-linked deubiquitination (GO:0035871)3.53699333
50microtubule polymerization or depolymerization (GO:0031109)3.52590458
51monoubiquitinated protein deubiquitination (GO:0035520)3.48969870
52genitalia morphogenesis (GO:0035112)3.44842442
53protein polyglutamylation (GO:0018095)3.29147943
54polyol catabolic process (GO:0046174)3.22667973
55glycolytic process (GO:0006096)3.21961605
56regulation of spindle checkpoint (GO:0090231)3.21498806
57nucleoside diphosphate phosphorylation (GO:0006165)3.21092663
58meiotic cell cycle (GO:0051321)3.17219394
59protein refolding (GO:0042026)3.13109742
60alditol metabolic process (GO:0019400)3.11696245
61GTP biosynthetic process (GO:0006183)3.05320877
62protein localization to cilium (GO:0061512)3.03853400
63amino-acid betaine transport (GO:0015838)3.00039541
64carnitine transport (GO:0015879)3.00039541
65nucleus organization (GO:0006997)2.99575494
66mitotic sister chromatid cohesion (GO:0007064)2.92636164
67positive regulation of macrophage activation (GO:0043032)2.85087852
68carnitine transmembrane transport (GO:1902603)2.81128137
69cilium organization (GO:0044782)2.74981514
70interferon-gamma secretion (GO:0072643)2.72744489
71synapsis (GO:0007129)2.71794082
72UTP biosynthetic process (GO:0006228)2.71126507
73lactate metabolic process (GO:0006089)2.70367115
74cilium morphogenesis (GO:0060271)2.69722504
75cellular component assembly involved in morphogenesis (GO:0010927)2.67797585
76microtubule-based movement (GO:0007018)2.67748042
77glycerol metabolic process (GO:0006071)2.65917878
78cilium assembly (GO:0042384)2.65677083
79meiotic cell cycle process (GO:1903046)2.60776821
80centriole assembly (GO:0098534)2.59425118
81regulation of cilium assembly (GO:1902017)2.59342586
82polyamine biosynthetic process (GO:0006596)2.58879889
83RNA destabilization (GO:0050779)2.58117311
84intraciliary transport (GO:0042073)2.57283469
85axoneme assembly (GO:0035082)2.55039619
86RNA localization (GO:0006403)2.54941141
87chromatin silencing (GO:0006342)2.47994961
88UTP metabolic process (GO:0046051)2.45928687
89cell redox homeostasis (GO:0045454)2.39034699
90fusion of sperm to egg plasma membrane (GO:0007342)14.3278996
91sperm motility (GO:0030317)14.1180436
92cell wall macromolecule metabolic process (GO:0044036)14.0591491
93cell wall macromolecule catabolic process (GO:0016998)14.0591491
94acrosome assembly (GO:0001675)12.1482527
95acrosome reaction (GO:0007340)12.1224743
96sperm-egg recognition (GO:0035036)11.7934817
97multicellular organism reproduction (GO:0032504)11.5023422
98plasma membrane fusion (GO:0045026)10.9480282
99binding of sperm to zona pellucida (GO:0007339)10.5987772
100cell-cell recognition (GO:0009988)10.5480607

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse9.21497960
2EZH2_22144423_ChIP-Seq_EOC_Human4.06576372
3TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse4.00589379
4BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse3.13331875
5GLI1_17442700_ChIP-ChIP_MESCs_Mouse3.09502202
6PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse2.95220284
7STAT6_21828071_ChIP-Seq_BEAS2B_Human2.66382443
8CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human2.51072409
9VDR_22108803_ChIP-Seq_LS180_Human2.46151848
10ZNF274_21170338_ChIP-Seq_K562_Hela2.21094827
11FLI1_27457419_Chip-Seq_LIVER_Mouse2.16865387
12CREM_20920259_ChIP-Seq_GC1-SPG_Mouse2.09091710
13EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human2.04889022
14GATA1_26923725_Chip-Seq_HPCs_Mouse2.00686063
15KLF4_25985364_ChIP-Seq_ATHEROSCLEROSIS_LESION_Mouse1.93603124
16GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.92405908
17ZFP322A_24550733_ChIP-Seq_MESCs_Mouse1.90424422
18TAL1_21186366_ChIP-Seq_BM-HSCs_Mouse1.79320385
19PCGF2_27294783_Chip-Seq_ESCs_Mouse1.78714773
20MEIS1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse1.75279150
21ELK4_26923725_Chip-Seq_MESODERM_Mouse1.74661789
22STAT1_17558387_ChIP-Seq_HELA_Human1.73113830
23CBX2_27304074_Chip-Seq_ESCs_Mouse1.66770366
24FLI1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.61824940
25SOX2_22085726_ChIP-Seq_NPCs_Mouse1.59877926
26GATA2_21186366_ChIP-Seq_BM-HSCs_Mouse1.59621492
27RCOR1_19997604_ChIP-ChIP_NEURONS_Mouse1.58293457
28KDM2B_26808549_Chip-Seq_REH_Human1.58044029
29TAL1_26923725_Chip-Seq_HPCs_Mouse1.55894596
30GATA3_21867929_ChIP-Seq_CD8_Mouse1.54401500
31KAP1_22055183_ChIP-Seq_ESCs_Mouse1.51205106
32WDR5_24793694_ChIP-Seq_LNCAP_Human1.50624839
33CBP_20019798_ChIP-Seq_JUKART_Human1.41008303
34IRF4_20064451_ChIP-Seq_CD4+T_Mouse1.41008303
35REST_21632747_ChIP-Seq_MESCs_Mouse1.36858801
36LUZP1_20508642_ChIP-Seq_ESCs_Mouse1.36430065
37GATA3_21867929_ChIP-Seq_TH1_Mouse1.36379136
38PBX_27287812_Chip-Seq_EMBYONIC-LIMB_Mouse1.34445318
39TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse1.31386104
40FLI1_21867929_ChIP-Seq_TH2_Mouse1.31205641
41CTBP2_25329375_ChIP-Seq_LNCAP_Human1.30910536
42NFE2_27457419_Chip-Seq_LIVER_Mouse1.30609978
43ZNF652_21678463_ChIP-ChIP_ZR75-1_Human1.29891017
44FLI1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse1.29497137
45PCGF2_27294783_Chip-Seq_NPCs_Mouse1.28555466
46P53_21459846_ChIP-Seq_SAOS-2_Human1.28038596
47MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.26411332
48GF1_26923725_Chip-Seq_HPCs_Mouse1.23959658
49TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.23920272
50SIN3B_21632747_ChIP-Seq_MESCs_Mouse1.22607332
51SUZ12_27294783_Chip-Seq_NPCs_Mouse1.22019482
52PPARG_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse1.16815059
53ZFP57_27257070_Chip-Seq_ESCs_Mouse1.16766465
54CRX_20693478_ChIP-Seq_RETINA_Mouse1.14895899
55RAD21_21589869_ChIP-Seq_MESCs_Mouse1.13983075
56NANOG_18555785_Chip-Seq_ESCs_Mouse1.13695577
57* CEBPB_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse1.12587018
58EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human1.12049001
59CDX2_21402776_ChIP-Seq_INTESTINAL-VILLUS_Mouse1.08691729
60CEBPB_26923725_Chip-Seq_MACROPHAGESS_Mouse1.08672769
61TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.08392696
62POU5F1_26923725_Chip-Seq_MESODERM_Mouse1.08392696
63SETDB1_19884257_ChIP-Seq_MESCs_Mouse1.08370077
64SPI1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.07491947
65SPI1_26923725_Chip-Seq_HPCs_Mouse1.06975666
66NFIB_24661679_ChIP-Seq_LUNG_Mouse1.05018290
67* PBX1_22567123_ChIP-ChIP_OVCAR3_Human1.03886276
68RUNX1_26923725_Chip-Seq_HPCs_Mouse1.03650470
69OCT4_18555785_Chip-Seq_ESCs_Mouse1.03605077
70ERG_20517297_ChIP-Seq_VCAP_Human1.02226189
71EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse1.02116262
72ESET_19884257_ChIP-Seq_ESCs_Mouse1.02113835
73P53_22387025_ChIP-Seq_ESCs_Mouse1.02064803
74MYC_27129775_Chip-Seq_CORNEA_Mouse1.01271167
75CMYC_18555785_Chip-Seq_ESCs_Mouse1.00936024
76RNF2_27304074_Chip-Seq_NSC_Mouse1.00773590
77MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse1.00396285
78RXRA_24833708_ChIP-Seq_LIVER_Mouse1.00248064
79GATA1_19941827_ChIP-Seq_MEL86_Mouse1.00224230
80SMAD2/3_21741376_ChIP-Seq_EPCs_Human0.98976526
81JARID1B-DAIN_22020125_ChIP-Seq_ESCs_Mouse0.98926941
82PPARG_20176806_ChIP-Seq_3T3-L1_Mouse0.98193513
83EBNA1_20929547_Chip-Seq_RAJI-cells_Human0.97578033
84RCOR3_21632747_ChIP-Seq_MESCs_Mouse0.97010162
85RARA_24833708_ChIP-Seq_LIVER_Mouse0.96059740
86P300_18555785_Chip-Seq_ESCs_Mouse0.95232299
87OCT4_21477851_ChIP-Seq_ESCs_Mouse0.94304496
88LDB1_21186366_ChIP-Seq_BM-HSCs_Mouse0.93903579
89KLF4_18555785_Chip-Seq_ESCs_Mouse0.92409348
90EZH2_27294783_Chip-Seq_NPCs_Mouse0.92224778
91KLF1_20508144_ChIP-Seq_FETAL-LIVER-ERYTHROID_Mouse0.91812520
92SOX9_26525672_Chip-Seq_HEART_Mouse0.91267099
93TET1_21451524_ChIP-Seq_MESCs_Mouse0.91142652
94SPI1_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse0.90641547
95GF1B_26923725_Chip-Seq_HPCs_Mouse0.90407092
96NFYB_21822215_ChIP-Seq_K562_Human0.90059459
97FLI1_21867929_ChIP-Seq_CD8_Mouse0.89674221
98ESRRB_18555785_Chip-Seq_ESCs_Mouse0.89096994
99EBF1_22473956_ChIP-Seq_LYMPHODE_Mouse0.88354372
100YY1_22570637_ChIP-Seq_MALME-3M_Human0.87368474

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0003698_abnormal_male_reproductive6.09130434
2MP0001929_abnormal_gametogenesis5.54088518
3MP0008877_abnormal_DNA_methylation4.00469162
4MP0002161_abnormal_fertility/fecundity3.32571903
5MP0002210_abnormal_sex_determination3.31850992
6MP0005670_abnormal_white_adipose2.91799202
7MP0001145_abnormal_male_reproductive2.80466257
8MP0000653_abnormal_sex_gland2.43627736
9MP0002653_abnormal_ependyma_morphology2.20725565
10MP0005410_abnormal_fertilization16.6912377
11MP0002160_abnormal_reproductive_system1.46432494
12MP0004233_abnormal_muscle_weight1.42042012
13MP0005623_abnormal_meninges_morphology1.31500417
14MP0001984_abnormal_olfaction1.27961394
15MP0003646_muscle_fatigue1.25325086
16MP0001765_abnormal_ion_homeostasis1.20767188
17MP0002282_abnormal_trachea_morphology1.13888566
18MP0002234_abnormal_pharynx_morphology1.01650608
19MP0009046_muscle_twitch0.90961804
20MP0005647_abnormal_sex_gland0.89732883
21MP0003329_amyloid_beta_deposits0.88733917
22MP0008058_abnormal_DNA_repair0.79492659
23MP0008995_early_reproductive_senescence0.75717852
24MP0003011_delayed_dark_adaptation0.73816307
25MP0005389_reproductive_system_phenotype0.69977418
26MP0005636_abnormal_mineral_homeostasis0.69378002
27MP0003115_abnormal_respiratory_system0.61929707
28MP0003878_abnormal_ear_physiology0.55121714
29MP0005377_hearing/vestibular/ear_phenot0.55121714
30MP0005666_abnormal_adipose_tissue0.54850757
31MP0001324_abnormal_eye_pigmentation0.54792366
32MP0001764_abnormal_homeostasis0.54308285
33MP0002736_abnormal_nociception_after0.52253472
34MP0000604_amyloidosis0.50488755
35MP0005551_abnormal_eye_electrophysiolog0.49788148
36MP0002102_abnormal_ear_morphology0.49729077
37MP0002928_abnormal_bile_duct0.49563108
38MP0002269_muscular_atrophy0.46763059
39MP0004036_abnormal_muscle_relaxation0.45395289
40MP0003699_abnormal_female_reproductive0.43101012
41MP0005253_abnormal_eye_physiology0.42162493
42MP0003950_abnormal_plasma_membrane0.41390156
43MP0001968_abnormal_touch/_nociception0.38418649
44MP0010094_abnormal_chromosome_stability0.38166921
45MP0000358_abnormal_cell_content/0.36768236
46MP0009115_abnormal_fat_cell0.35240738
47MP0002971_abnormal_brown_adipose0.35214547
48MP0001293_anophthalmia0.32870520
49MP0001545_abnormal_hematopoietic_system0.32617404
50MP0005397_hematopoietic_system_phenotyp0.32617404
51MP0000569_abnormal_digit_pigmentation0.31342444
52MP0003633_abnormal_nervous_system0.31338506
53MP0006036_abnormal_mitochondrial_physio0.31141854
54MP0002139_abnormal_hepatobiliary_system0.29710275
55MP0000534_abnormal_ureter_morphology0.28534369
56MP0004811_abnormal_neuron_physiology0.27546164
57MP0004133_heterotaxia0.27474884
58MP0003631_nervous_system_phenotype0.27116650
59MP0001119_abnormal_female_reproductive0.26676446
60MP0005391_vision/eye_phenotype0.26426714
61MP0008875_abnormal_xenobiotic_pharmacok0.25829721
62MP0004019_abnormal_vitamin_homeostasis0.25089577
63MP0004145_abnormal_muscle_electrophysio0.22985080
64MP0003942_abnormal_urinary_system0.22811908
65MP0003879_abnormal_hair_cell0.22030138
66MP0002169_no_abnormal_phenotype0.21467777
67MP0002873_normal_phenotype0.21275602
68MP0005423_abnormal_somatic_nervous0.21257121
69MP0002152_abnormal_brain_morphology0.21129284
70MP0003786_premature_aging0.20667006
71MP0003861_abnormal_nervous_system0.20630206
72MP0002572_abnormal_emotion/affect_behav0.20420340
73MP0004742_abnormal_vestibular_system0.20278339
74MP0008057_abnormal_DNA_replication0.20125379
75MP0009278_abnormal_bone_marrow0.20093424
76MP0005535_abnormal_body_temperature0.19722707
77MP0001849_ear_inflammation0.19001506
78MP0004270_analgesia0.18365383
79MP0003948_abnormal_gas_homeostasis0.18064392
80MP0010307_abnormal_tumor_latency0.17099272
81MP0002693_abnormal_pancreas_physiology0.17006161
82MP0002295_abnormal_pulmonary_circulatio0.16418588
83MP0008961_abnormal_basal_metabolism0.16416973
84MP0001440_abnormal_grooming_behavior0.16240622
85MP0005319_abnormal_enzyme/_coenzyme0.15980611
86MP0005195_abnormal_posterior_eye0.15386535
87MP0001730_embryonic_growth_arrest0.15321903
88MP0003111_abnormal_nucleus_morphology0.15279442
89MP0006035_abnormal_mitochondrial_morpho0.15251797
90MP0008569_lethality_at_weaning0.14890811
91MP0002229_neurodegeneration0.14871619
92MP0002405_respiratory_system_inflammati0.14698244
93MP0004043_abnormal_pH_regulation0.14120545
94MP0001529_abnormal_vocalization0.13846806
95MP0000001_mammalian_phenotype0.13581599
96MP0005375_adipose_tissue_phenotype0.13494380
97MP0003635_abnormal_synaptic_transmissio0.12394231
98MP0003632_abnormal_nervous_system0.11965034
99MP0002272_abnormal_nervous_system0.11713159
100MP0002063_abnormal_learning/memory/cond0.11381647

Predicted human phenotypes

RankGene SetZ-score
1Abnormal respiratory epithelium morphology (HP:0012253)9.52587850
2Abnormal respiratory motile cilium morphology (HP:0005938)9.52587850
3Abnormal respiratory motile cilium physiology (HP:0012261)9.49355716
4Abnormal ciliary motility (HP:0012262)7.63748095
5Rhinitis (HP:0012384)7.48108296
6Chronic bronchitis (HP:0004469)7.44962465
7Infertility (HP:0000789)6.85911310
8Nasal polyposis (HP:0100582)6.36296697
9Abnormality of the nasal mucosa (HP:0000433)5.23296880
10Male infertility (HP:0003251)4.65899869
11Bronchitis (HP:0012387)4.51382362
12Bronchiectasis (HP:0002110)4.36723228
13Nephronophthisis (HP:0000090)3.88022164
14Recurrent sinusitis (HP:0011108)3.57078532
15Abnormal spermatogenesis (HP:0008669)3.51986957
16Recurrent otitis media (HP:0000403)3.22373411
17Abnormality of the renal medulla (HP:0100957)2.93210117
18Tubulointerstitial nephritis (HP:0001970)2.70532130
19Medial flaring of the eyebrow (HP:0010747)2.67155655
20Recurrent bronchitis (HP:0002837)2.55662294
21Molar tooth sign on MRI (HP:0002419)2.47402874
22Abnormality of midbrain morphology (HP:0002418)2.47402874
23Impulsivity (HP:0100710)2.45499999
24Tubular atrophy (HP:0000092)2.35115086
25Tubulointerstitial abnormality (HP:0001969)2.25749921
26Gonadotropin excess (HP:0000837)2.21979009
27Azoospermia (HP:0000027)2.20834294
28Abnormal gallbladder physiology (HP:0012438)2.18017124
29Cholecystitis (HP:0001082)2.18017124
30Dynein arm defect of respiratory motile cilia (HP:0012255)13.8877806
31Absent/shortened dynein arms (HP:0200106)13.8877806
32Respiratory insufficiency due to defective ciliary clearance (HP:0200073)13.0775281
33Dyschromatopsia (HP:0007641)1.99117204
34Choroideremia (HP:0001139)1.88047362
35Decreased central vision (HP:0007663)1.85721029
36Spastic tetraparesis (HP:0001285)1.85153388
37Tubulointerstitial fibrosis (HP:0005576)1.77756284
38Stage 5 chronic kidney disease (HP:0003774)1.68750327
39Gait imbalance (HP:0002141)1.68742613
40Congenital primary aphakia (HP:0007707)1.68720761
41Hemorrhage of the eye (HP:0011885)1.67008868
42Aplasia/Hypoplasia of the lens (HP:0008063)1.65681726
43Postaxial foot polydactyly (HP:0001830)1.64004421
44Congenital malformation of the right heart (HP:0011723)1.59722705
45Double outlet right ventricle (HP:0001719)1.59722705
46Heterotopia (HP:0002282)1.57332231
47Polydipsia (HP:0001959)1.56677550
48Abnormal drinking behavior (HP:0030082)1.56677550
49Neurofibrillary tangles (HP:0002185)1.56214182
50Abnormality of renal excretion (HP:0011036)1.54464298
51Abnormality of the renal cortex (HP:0011035)1.53934406
52Congenital hepatic fibrosis (HP:0002612)1.53696611
53Chronic sinusitis (HP:0011109)1.53193368
54Hypoplasia of the capital femoral epiphysis (HP:0003090)1.48309255
55Decreased electroretinogram (ERG) amplitude (HP:0000654)1.47585494
56Bundle branch block (HP:0011710)1.46245798
57Abnormal biliary tract physiology (HP:0012439)1.44961729
58Bile duct proliferation (HP:0001408)1.44961729
59Asymmetric septal hypertrophy (HP:0001670)1.44719554
60Nephrogenic diabetes insipidus (HP:0009806)1.44297474
61Postaxial hand polydactyly (HP:0001162)1.44189265
62Abnormality of permanent molar morphology (HP:0011071)1.43282873
63Abnormality of the dental root (HP:0006486)1.43282873
64Taurodontia (HP:0000679)1.43282873
65Oculomotor apraxia (HP:0000657)1.40083649
66Sensory axonal neuropathy (HP:0003390)1.38715692
67Short ribs (HP:0000773)1.37988507
68Abnormality of dentin (HP:0010299)1.36709618
69Fibular hypoplasia (HP:0003038)1.36051590
70Constricted visual fields (HP:0001133)1.35906346
71Hemiparesis (HP:0001269)1.35087588
72Abnormality of the dental pulp (HP:0006479)1.34647016
73Easy fatigability (HP:0003388)1.33802476
74Bell-shaped thorax (HP:0001591)1.33328720
75Abnormality of molar morphology (HP:0011070)1.31931696
76Abnormality of molar (HP:0011077)1.31931696
77Vaginal atresia (HP:0000148)1.31223134
78Cerebral inclusion bodies (HP:0100314)1.30795974
79Renal dysplasia (HP:0000110)1.30663630
80Fatigable weakness (HP:0003473)1.30099471
81Abnormality of the neuromuscular junction (HP:0003398)1.30099471
82Facial cleft (HP:0002006)1.30066596
83Genital tract atresia (HP:0001827)1.28009457
84Cerebellar dysplasia (HP:0007033)1.25613526
85Poor coordination (HP:0002370)1.24942450
86Abnormal urine output (HP:0012590)1.23611367
87Cystic liver disease (HP:0006706)1.23039888
88Abnormality of saccadic eye movements (HP:0000570)1.21535389
89Exercise-induced myalgia (HP:0003738)1.20353793
90Abnormality of ocular smooth pursuit (HP:0000617)1.17930734
91Deformed sella turcica (HP:0002681)1.17282942
92Myoglobinuria (HP:0002913)1.17246938
93Aplasia/Hypoplasia affecting the fundus (HP:0008057)1.16327630
94Absent epiphyses (HP:0010577)1.16054508
95Aplasia/Hypoplasia of the capital femoral epiphysis (HP:0005003)1.16054508
96Hypercholesterolemia (HP:0003124)1.14551908
97Retinal atrophy (HP:0001105)1.14021512
98Supernumerary spleens (HP:0009799)1.13695450
99Retinal dysplasia (HP:0007973)1.13122474
100Pancreatic fibrosis (HP:0100732)1.13113219

Predicted kinase interactions (KEA)

RankGene SetZ-score
1PDK38.52003949
2PDK48.52003949
3TESK15.85807060
4PDK25.54743893
5PRKD34.79230385
6ICK4.20655985
7WNK42.16891839
8PTK2B2.12963315
9STK392.10665546
10PNCK1.88733741
11STK381.71009206
12DYRK1B1.56440824
13NEK21.39475388
14PDK11.20142404
15TYRO30.86437466
16IRAK10.84436169
17WNK10.83994479
18RIPK40.83837438
19MAPK150.81217155
20DYRK30.79351485
21CCNB10.73254899
22PDPK10.71434429
23PASK0.67599641
24TESK20.65743748
25MAP2K60.62129445
26CHEK20.57880036
27LMTK20.56368131
28STK30.54260869
29NTRK20.49390642
30CAMK1G0.48466723
31TTK0.45777814
32MUSK0.44710086
33EEF2K0.44409796
34PINK10.41906153
35IRAK20.39527740
36PLK40.38003844
37PAK10.36399705
38PRKCG0.36054846
39CHEK10.33825292
40MAPKAPK50.31114265
41STK38L0.30780875
42MARK20.28340200
43MAP3K100.27051667
44PAK20.26761459
45ATM0.24363822
46CAMKK10.23197071
47MARK30.21217529
48MTOR0.19796078
49NEK60.18815342
50WEE10.18739510
51ATR0.18255904
52PRKCQ0.16766185
53PRKCZ0.16433174
54BRSK20.16306513
55CDK150.15226024
56MAP3K20.14305771
57PRKAA10.13951504
58PAK40.13058550
59CDK180.12580280
60BRAF0.12459623
61PRKG20.12060705
62PKN10.12003821
63CDK120.11290146
64CDK11A0.11158150
65PLK10.09634026
66CDK140.09608643
67RPS6KB10.08487603
68PRKG10.08282237
69RPS6KA10.07367169
70BRSK10.06679244
71CSNK2A10.06390185
72CAMK2A0.05834157
73PRKCD0.05817839
74PRKACG0.05322116
75GSK3B0.05003281
76CSNK1D0.04721962
77PIM10.04079137
78PRKCA0.03082741
79EGFR0.03007103
80YES10.02972186
81CDC70.02730197
82PBK0.02629910
83PRKCB0.02221907
84CDK60.02118158
85ZAP700.02038126
86MAPK80.00981231
87CDK20.00662233
88CDK10.00641362
89CSNK2A20.00614271
90STK110.00382357
91CSF1R0.00195350
92CDK3-0.0394056
93NTRK3-0.0323129
94PRKACB-0.0275266
95MAP3K1-0.0264911
96PRKACA-0.0171442
97WNK3-0.0164677
98MAP3K4-0.0115922
99RPS6KA3-0.0094016
100STK10-0.0020095

Predicted pathways (KEGG)

RankGene SetZ-score
1Fatty acid biosynthesis_Homo sapiens_hsa000614.62356937
2Glycolysis / Gluconeogenesis_Homo sapiens_hsa000104.60794310
3Vitamin B6 metabolism_Homo sapiens_hsa007503.76846441
4Pyruvate metabolism_Homo sapiens_hsa006203.52888809
5alpha-Linolenic acid metabolism_Homo sapiens_hsa005922.88010723
6Linoleic acid metabolism_Homo sapiens_hsa005912.79675857
7Propanoate metabolism_Homo sapiens_hsa006402.77949346
8Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049642.76754117
9Glucagon signaling pathway_Homo sapiens_hsa049222.57827546
10Carbohydrate digestion and absorption_Homo sapiens_hsa049732.33974137
11Basal transcription factors_Homo sapiens_hsa030222.27542719
12Butirosin and neomycin biosynthesis_Homo sapiens_hsa005242.27081055
13Protein processing in endoplasmic reticulum_Homo sapiens_hsa041411.97937725
14Glycerolipid metabolism_Homo sapiens_hsa005611.97006029
15PPAR signaling pathway_Homo sapiens_hsa033201.88102819
16Selenocompound metabolism_Homo sapiens_hsa004501.87806101
17Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007601.80905737
18Glycosaminoglycan degradation_Homo sapiens_hsa005311.77721913
19Pentose phosphate pathway_Homo sapiens_hsa000301.73401645
20Oocyte meiosis_Homo sapiens_hsa041141.62058730
21Fructose and mannose metabolism_Homo sapiens_hsa000511.59443610
22Mineral absorption_Homo sapiens_hsa049781.55352086
23Glycerophospholipid metabolism_Homo sapiens_hsa005641.53160317
24Amphetamine addiction_Homo sapiens_hsa050311.51538000
25Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049611.48435198
26Cardiac muscle contraction_Homo sapiens_hsa042601.47010830
27Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005121.41106841
28Ether lipid metabolism_Homo sapiens_hsa005651.40529898
29Longevity regulating pathway - multiple species_Homo sapiens_hsa042131.38809857
30Carbon metabolism_Homo sapiens_hsa012001.38191413
31Fat digestion and absorption_Homo sapiens_hsa049751.33735372
32Dorso-ventral axis formation_Homo sapiens_hsa043201.31930763
33Fatty acid metabolism_Homo sapiens_hsa012121.31847877
34Fatty acid degradation_Homo sapiens_hsa000711.31232648
35Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049601.22890337
36Collecting duct acid secretion_Homo sapiens_hsa049661.21674502
37Cysteine and methionine metabolism_Homo sapiens_hsa002701.21008160
38Renin secretion_Homo sapiens_hsa049241.15329119
39Fanconi anemia pathway_Homo sapiens_hsa034601.07157918
40Huntingtons disease_Homo sapiens_hsa050161.06060018
41Drug metabolism - cytochrome P450_Homo sapiens_hsa009821.03089850
42Antigen processing and presentation_Homo sapiens_hsa046121.01412967
43Purine metabolism_Homo sapiens_hsa002300.99476947
44Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.97006581
45Glutathione metabolism_Homo sapiens_hsa004800.95135618
46Biosynthesis of amino acids_Homo sapiens_hsa012300.90994315
47Insulin secretion_Homo sapiens_hsa049110.83499740
48Chemical carcinogenesis_Homo sapiens_hsa052040.82178320
49Long-term potentiation_Homo sapiens_hsa047200.78487476
50Hedgehog signaling pathway_Homo sapiens_hsa043400.78146796
51mRNA surveillance pathway_Homo sapiens_hsa030150.75592883
52Thyroid hormone synthesis_Homo sapiens_hsa049180.73282333
53Bile secretion_Homo sapiens_hsa049760.73114065
54Adipocytokine signaling pathway_Homo sapiens_hsa049200.71422064
55Arachidonic acid metabolism_Homo sapiens_hsa005900.70814548
56cGMP-PKG signaling pathway_Homo sapiens_hsa040220.70018866
57Estrogen signaling pathway_Homo sapiens_hsa049150.65907935
58Synaptic vesicle cycle_Homo sapiens_hsa047210.62887680
59RNA transport_Homo sapiens_hsa030130.62178387
60Legionellosis_Homo sapiens_hsa051340.60771309
61Calcium signaling pathway_Homo sapiens_hsa040200.58761619
62Renin-angiotensin system_Homo sapiens_hsa046140.58649053
63Salivary secretion_Homo sapiens_hsa049700.55837586
64Pancreatic secretion_Homo sapiens_hsa049720.55165044
65Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.54473617
66Central carbon metabolism in cancer_Homo sapiens_hsa052300.52307703
67Inositol phosphate metabolism_Homo sapiens_hsa005620.51210269
68Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.50460713
69Protein digestion and absorption_Homo sapiens_hsa049740.48962138
70Gastric acid secretion_Homo sapiens_hsa049710.46212210
71Sulfur metabolism_Homo sapiens_hsa009200.45924338
72Phosphatidylinositol signaling system_Homo sapiens_hsa040700.44365086
73Systemic lupus erythematosus_Homo sapiens_hsa053220.43738848
74Taste transduction_Homo sapiens_hsa047420.43544494
75Vascular smooth muscle contraction_Homo sapiens_hsa042700.41109400
76ABC transporters_Homo sapiens_hsa020100.40712395
77Metabolic pathways_Homo sapiens_hsa011000.40688763
78Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042610.38799540
79Citrate cycle (TCA cycle)_Homo sapiens_hsa000200.36840044
80Vasopressin-regulated water reabsorption_Homo sapiens_hsa049620.36800962
81Endocytosis_Homo sapiens_hsa041440.36703282
82Thyroid hormone signaling pathway_Homo sapiens_hsa049190.35565730
83Pentose and glucuronate interconversions_Homo sapiens_hsa000400.35020946
84cAMP signaling pathway_Homo sapiens_hsa040240.34842135
85Circadian entrainment_Homo sapiens_hsa047130.33390991
86VEGF signaling pathway_Homo sapiens_hsa043700.32603328
87Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006300.30664269
88AMPK signaling pathway_Homo sapiens_hsa041520.28580027
89Pyrimidine metabolism_Homo sapiens_hsa002400.25437430
90N-Glycan biosynthesis_Homo sapiens_hsa005100.24578739
91Cocaine addiction_Homo sapiens_hsa050300.17152616
92Alcoholism_Homo sapiens_hsa050340.16017962
93B cell receptor signaling pathway_Homo sapiens_hsa046620.15201802
94Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010400.13365405
95Glutamatergic synapse_Homo sapiens_hsa047240.13057378
96Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.12530367
97Salmonella infection_Homo sapiens_hsa051320.08247119
98Wnt signaling pathway_Homo sapiens_hsa043100.07405355
99HIF-1 signaling pathway_Homo sapiens_hsa040660.07316765
100Vibrio cholerae infection_Homo sapiens_hsa051100.03233280

Most similar genes based on co-expression Upload to Enrichr

Tissue Expression Export image »

Cell Line Expression Export image »