TCAF1

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1regulation of short-term neuronal synaptic plasticity (GO:0048172)5.53929307
2vocalization behavior (GO:0071625)5.33890533
3neuron cell-cell adhesion (GO:0007158)5.09238845
4synaptic vesicle maturation (GO:0016188)5.06764176
5positive regulation of calcium ion-dependent exocytosis (GO:0045956)4.99275520
6locomotory exploration behavior (GO:0035641)4.97395873
7synaptic vesicle exocytosis (GO:0016079)4.97079643
8positive regulation of excitatory postsynaptic membrane potential (GO:2000463)4.94966998
9regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor act4.93188326
10protein localization to synapse (GO:0035418)4.68987832
11regulation of glutamate receptor signaling pathway (GO:1900449)4.57387461
12regulation of synaptic vesicle exocytosis (GO:2000300)4.56382513
13glutamate secretion (GO:0014047)4.54499041
14layer formation in cerebral cortex (GO:0021819)4.50448699
15nucleobase catabolic process (GO:0046113)4.30006107
16exploration behavior (GO:0035640)4.29821988
17ionotropic glutamate receptor signaling pathway (GO:0035235)4.29344699
18synaptic vesicle docking involved in exocytosis (GO:0016081)4.21277959
19neuron recognition (GO:0008038)4.20792955
20dendritic spine morphogenesis (GO:0060997)4.19585781
21neurotransmitter secretion (GO:0007269)4.03586568
22regulation of synapse structural plasticity (GO:0051823)3.97462745
23axonal fasciculation (GO:0007413)3.96185194
24regulation of synaptic vesicle transport (GO:1902803)3.95429042
25regulation of long-term neuronal synaptic plasticity (GO:0048169)3.95269543
26regulation of N-methyl-D-aspartate selective glutamate receptor activity (GO:2000310)3.92925329
27glutamate receptor signaling pathway (GO:0007215)3.92108154
28regulation of neuronal synaptic plasticity (GO:0048168)3.91617115
29neuronal action potential propagation (GO:0019227)3.84545254
30synaptic transmission, glutamatergic (GO:0035249)3.80168269
31neuron-neuron synaptic transmission (GO:0007270)3.74562126
32neurotransmitter-gated ion channel clustering (GO:0072578)3.72592980
33postsynaptic membrane organization (GO:0001941)3.69303336
34gamma-aminobutyric acid transport (GO:0015812)3.63957323
35regulation of inhibitory postsynaptic membrane potential (GO:0060080)3.59757840
36proline transport (GO:0015824)3.59049999
37positive regulation of synapse maturation (GO:0090129)3.57477126
38dendrite morphogenesis (GO:0048813)3.55416905
39axon extension (GO:0048675)3.54482624
40presynaptic membrane assembly (GO:0097105)3.49711569
41transmission of nerve impulse (GO:0019226)3.44476613
42regulation of excitatory postsynaptic membrane potential (GO:0060079)3.43605804
43cell migration in hindbrain (GO:0021535)3.41191795
44long-term memory (GO:0007616)3.40138144
45establishment of mitochondrion localization (GO:0051654)3.35737987
46gamma-aminobutyric acid signaling pathway (GO:0007214)3.35724381
47positive regulation of membrane potential (GO:0045838)3.35124666
48regulation of dendritic spine morphogenesis (GO:0061001)3.35123462
49membrane depolarization during cardiac muscle cell action potential (GO:0086012)3.33648460
50regulation of postsynaptic membrane potential (GO:0060078)3.32782124
51activation of protein kinase A activity (GO:0034199)3.31264231
52neurotransmitter transport (GO:0006836)3.31158138
53presynaptic membrane organization (GO:0097090)3.28584816
54neuron projection extension involved in neuron projection guidance (GO:1902284)3.25985046
55axon extension involved in axon guidance (GO:0048846)3.25985046
56synapse assembly (GO:0007416)3.25908574
57positive regulation of synaptic transmission, GABAergic (GO:0032230)3.24345769
58regulation of respiratory gaseous exchange by neurological system process (GO:0002087)3.23460100
59auditory behavior (GO:0031223)3.20785157
60regulation of synaptic transmission, glutamatergic (GO:0051966)3.19785487
61synaptic vesicle endocytosis (GO:0048488)3.17225733
62innervation (GO:0060384)3.15449414
63regulation of synaptic plasticity (GO:0048167)3.14781847
64negative regulation of synaptic transmission, GABAergic (GO:0032229)3.14229797
65central nervous system projection neuron axonogenesis (GO:0021952)3.13482542
66long-term synaptic potentiation (GO:0060291)3.12082327
67regulation of neurotransmitter secretion (GO:0046928)3.11177658
68cerebral cortex radially oriented cell migration (GO:0021799)3.10093436
69positive regulation of potassium ion transmembrane transporter activity (GO:1901018)3.09634318
70cellular potassium ion homeostasis (GO:0030007)3.08655380
71positive regulation of synaptic transmission, glutamatergic (GO:0051968)3.08538823
72cerebellar Purkinje cell differentiation (GO:0021702)3.08250928
73regulation of axon guidance (GO:1902667)3.07989120
74positive regulation of synapse assembly (GO:0051965)3.07281715
75regulation of vesicle fusion (GO:0031338)3.05973681
76neuromuscular process controlling balance (GO:0050885)3.04702417
77regulation of neurotransmitter levels (GO:0001505)3.04638401
78negative regulation of synaptic transmission, glutamatergic (GO:0051967)3.03858308
79mating behavior (GO:0007617)3.02285250
80regulation of axon extension involved in axon guidance (GO:0048841)3.02220781
81response to auditory stimulus (GO:0010996)3.02117920
82synapse organization (GO:0050808)3.01011964
83retinal ganglion cell axon guidance (GO:0031290)3.00081574
84establishment of mitochondrion localization, microtubule-mediated (GO:0034643)2.99305726
85mitochondrion transport along microtubule (GO:0047497)2.99305726
86prepulse inhibition (GO:0060134)2.98456397
87neuron projection extension (GO:1990138)2.97355050
88G-protein coupled glutamate receptor signaling pathway (GO:0007216)2.97244730
89vesicle transport along microtubule (GO:0047496)2.95554412
90behavioral defense response (GO:0002209)2.94974448
91behavioral fear response (GO:0001662)2.94974448
92dendritic spine organization (GO:0097061)2.92866196
93organelle transport along microtubule (GO:0072384)2.92482027
94membrane hyperpolarization (GO:0060081)2.91755858
95neuronal ion channel clustering (GO:0045161)2.91569834
96learning (GO:0007612)2.91559877
97positive regulation of dendritic spine morphogenesis (GO:0061003)2.91420018
98cerebellar granule cell differentiation (GO:0021707)2.91177334
99substrate-independent telencephalic tangential migration (GO:0021826)2.90919201
100substrate-independent telencephalic tangential interneuron migration (GO:0021843)2.90919201
101negative regulation of axon guidance (GO:1902668)2.90877131
102membrane depolarization (GO:0051899)2.90145888
103positive regulation of dendritic spine development (GO:0060999)2.88806439
104pyrimidine nucleobase catabolic process (GO:0006208)2.88524900
105response to histamine (GO:0034776)2.88194405
106regulation of neurotransmitter transport (GO:0051588)2.87451490
107regulation of dendritic spine development (GO:0060998)2.87313375
108startle response (GO:0001964)2.84812538
109regulation of synapse maturation (GO:0090128)2.84774013
110negative regulation of microtubule polymerization (GO:0031115)2.83699098
111social behavior (GO:0035176)2.82491760
112intraspecies interaction between organisms (GO:0051703)2.82491760
113positive regulation of neurotransmitter secretion (GO:0001956)2.82289584
114fear response (GO:0042596)2.80989948
115membrane depolarization during action potential (GO:0086010)2.80493772
116negative regulation of axon extension involved in axon guidance (GO:0048843)2.77460570
117behavioral response to nicotine (GO:0035095)2.75026646
118ganglion development (GO:0061548)2.72728745
119calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules (GO:0016339)2.69754511
120spinal cord development (GO:0021510)2.67443287
121neurofilament cytoskeleton organization (GO:0060052)2.58103342
122regulation of synapse assembly (GO:0051963)2.47847040
123establishment of nucleus localization (GO:0040023)2.46988317
124adenylate cyclase-activating dopamine receptor signaling pathway (GO:0007191)2.46160310
125negative chemotaxis (GO:0050919)2.44497135
126negative regulation of catenin import into nucleus (GO:0035414)2.41670173
127negative regulation of cytosolic calcium ion concentration (GO:0051481)2.40718272
128spinal cord association neuron differentiation (GO:0021527)2.40250819
129developmental cell growth (GO:0048588)2.37635832
130limb bud formation (GO:0060174)2.37107089
131camera-type eye morphogenesis (GO:0048593)2.36261761
132dendrite development (GO:0016358)2.35939738
133hippocampus development (GO:0021766)2.35564961
134short-term memory (GO:0007614)2.34614487
135ephrin receptor signaling pathway (GO:0048013)2.34407343
136cerebral cortex cell migration (GO:0021795)2.29649080
137embryonic retina morphogenesis in camera-type eye (GO:0060059)2.27026302
138axon cargo transport (GO:0008088)2.25619309
139neuron migration (GO:0001764)2.25609870
140apical protein localization (GO:0045176)2.25524603
141negative regulation of axon extension (GO:0030517)2.23943529
142establishment or maintenance of monopolar cell polarity (GO:0061339)2.21383411
143establishment of monopolar cell polarity (GO:0061162)2.21383411
144olfactory bulb development (GO:0021772)2.20161927
145glucocorticoid biosynthetic process (GO:0006704)2.18915354
146adult walking behavior (GO:0007628)2.17928687
147regulation of synapse organization (GO:0050807)2.15895623
148regulation of growth hormone secretion (GO:0060123)2.15275147
149central nervous system neuron axonogenesis (GO:0021955)2.14561804
150body morphogenesis (GO:0010171)2.13418209
151positive regulation of dendrite morphogenesis (GO:0050775)2.12727141
152neuromuscular synaptic transmission (GO:0007274)2.11857270

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1EZH2_22144423_ChIP-Seq_EOC_Human5.83217618
2GBX2_23144817_ChIP-Seq_PC3_Human3.60856006
3RBPJ_22232070_ChIP-Seq_NCS_Mouse3.19448376
4SUZ12_18692474_ChIP-Seq_MESCs_Mouse3.11505214
5JARID2_20064375_ChIP-Seq_MESCs_Mouse3.05058152
6SUZ12_18555785_ChIP-Seq_MESCs_Mouse3.02836611
7EZH2_18974828_ChIP-Seq_MESCs_Mouse2.73617262
8RNF2_18974828_ChIP-Seq_MESCs_Mouse2.73617262
9EZH2_27304074_Chip-Seq_ESCs_Mouse2.67076303
10JARID2_20075857_ChIP-Seq_MESCs_Mouse2.62428241
11SUZ12_18974828_ChIP-Seq_MESCs_Mouse2.61034507
12SUZ12_16625203_ChIP-ChIP_MESCs_Mouse2.57296297
13SUZ12_18692474_ChIP-Seq_MEFs_Mouse2.54375983
14REST_21632747_ChIP-Seq_MESCs_Mouse2.50173517
15MTF2_20144788_ChIP-Seq_MESCs_Mouse2.43707280
16EED_16625203_ChIP-ChIP_MESCs_Mouse2.41597334
17SUZ12_20075857_ChIP-Seq_MESCs_Mouse2.40534195
18GLI1_17442700_ChIP-ChIP_MESCs_Mouse2.29256815
19EZH2_27294783_Chip-Seq_ESCs_Mouse2.24041612
20SUZ12_27294783_Chip-Seq_ESCs_Mouse2.21676451
21NR4A2_19515692_ChIP-ChIP_MN9D_Mouse2.21465129
22RNF2_27304074_Chip-Seq_ESCs_Mouse2.20165698
23DROSHA_22980978_ChIP-Seq_HELA_Human2.19809365
24RARB_27405468_Chip-Seq_BRAIN_Mouse2.19790174
25ZFP322A_24550733_ChIP-Seq_MESCs_Mouse2.06885606
26CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons2.06490357
27REST_18959480_ChIP-ChIP_MESCs_Mouse2.01961855
28CTBP2_25329375_ChIP-Seq_LNCAP_Human1.99388656
29AR_21572438_ChIP-Seq_LNCaP_Human1.87557106
30TAF15_26573619_Chip-Seq_HEK293_Human1.83226586
31CTBP1_25329375_ChIP-Seq_LNCAP_Human1.77675109
32IKZF1_21737484_ChIP-ChIP_HCT116_Human1.74739615
33TRIM28_21343339_ChIP-Seq_HEK293_Human1.64463830
34SMAD4_21799915_ChIP-Seq_A2780_Human1.63973508
35PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.63559237
36ZFP57_27257070_Chip-Seq_ESCs_Mouse1.59272370
37ZNF274_21170338_ChIP-Seq_K562_Hela1.58658355
38PHC1_16625203_ChIP-ChIP_MESCs_Mouse1.57446260
39CBX2_27304074_Chip-Seq_ESCs_Mouse1.56683194
40SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.55633430
41EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.52266755
42RNF2_16625203_ChIP-ChIP_MESCs_Mouse1.51537226
43P300_19829295_ChIP-Seq_ESCs_Human1.47725947
44MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human1.46516714
45BMI1_23680149_ChIP-Seq_NPCS_Mouse1.46057758
46ERG_21242973_ChIP-ChIP_JURKAT_Human1.42472558
47SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.42217516
48EP300_20729851_ChIP-Seq_FORBRAIN_MIDBRAIN_LIMB_HEART_Mouse1.40538528
49SMAD3_21741376_ChIP-Seq_EPCs_Human1.39492993
50IGF1R_20145208_ChIP-Seq_DFB_Human1.37373022
51OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.36301109
52RING1B_27294783_Chip-Seq_ESCs_Mouse1.36183245
53SOX2_21211035_ChIP-Seq_LN229_Gbm1.35194171
54NR3C1_23031785_ChIP-Seq_PC12_Mouse1.34336529
55OLIG2_26023283_ChIP-Seq_AINV15_Mouse1.33974776
56PIAS1_25552417_ChIP-Seq_VCAP_Human1.33552713
57TOP2B_26459242_ChIP-Seq_MCF-7_Human1.32840296
58SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.32706096
59WT1_19549856_ChIP-ChIP_CCG9911_Human1.29346089
60RCOR2_21632747_ChIP-Seq_MESCs_Mouse1.28123629
61TP53_20018659_ChIP-ChIP_R1E_Mouse1.27542969
62AR_25329375_ChIP-Seq_VCAP_Human1.27113453
63CDX2_19796622_ChIP-Seq_MESCs_Mouse1.26195183
64SALL1_21062744_ChIP-ChIP_HESCs_Human1.26081373
65POU3F2_20337985_ChIP-ChIP_501MEL_Human1.24784097
66RNF2_27304074_Chip-Seq_NSC_Mouse1.24136504
67STAT3_23295773_ChIP-Seq_U87_Human1.21980693
68RING1B_27294783_Chip-Seq_NPCs_Mouse1.21423613
69SMAD3_22036565_ChIP-Seq_ESCs_Mouse1.21268677
70SMAD_19615063_ChIP-ChIP_OVARY_Human1.21182291
71HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse1.20961491
72FUS_26573619_Chip-Seq_HEK293_Human1.19580460
73AR_19668381_ChIP-Seq_PC3_Human1.19161449
74KLF4_25985364_ChIP-Seq_ATHEROSCLEROSIS_LESION_Mouse1.18012413
75TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat1.16293399
76MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse1.15822729
77TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human1.15669086
78EP300_21415370_ChIP-Seq_HL-1_Mouse1.15348152
79ZNF217_24962896_ChIP-Seq_MCF-7_Human1.15234241
80ARNT_22903824_ChIP-Seq_MCF-7_Human1.15079417
81STAT3_24763339_ChIP-Seq_IMN-ESCs_Mouse1.14623375
82AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human1.12547672
83WT1_25993318_ChIP-Seq_PODOCYTE_Human1.12519819
84WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse1.12195943
85AHR_22903824_ChIP-Seq_MCF-7_Human1.11409462
86ISL1_27105846_Chip-Seq_CPCs_Mouse1.11027247
87CEBPD_23245923_ChIP-Seq_MEFs_Mouse1.09918184
88YAP1_20516196_ChIP-Seq_MESCs_Mouse1.09793526
89GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.07716394
90RCOR3_21632747_ChIP-Seq_MESCs_Mouse1.07166417
91TCF4_23295773_ChIP-Seq_U87_Human1.07152785
92TEAD4_22529382_ChIP-Seq_TROPHECTODERM_Mouse1.05695498
93RUNX2_22187159_ChIP-Seq_PCA_Human1.04596349
94P53_22127205_ChIP-Seq_FIBROBLAST_Human1.04345884
95UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human1.02943763
96LMO2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.02737140
97NR3C1_21868756_ChIP-Seq_MCF10A_Human1.01914236
98SOX9_26525672_Chip-Seq_HEART_Mouse1.01764249
99TCF3_18467660_ChIP-ChIP_MESCs_Mouse1.01364843
100TBX3_20139965_ChIP-Seq_MESCs_Mouse1.00658919
101TBX3_20139965_ChIP-Seq_ESCs_Mouse1.00286701
102POU5F1_16153702_ChIP-ChIP_HESCs_Human1.00253148
103MEIS1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse0.98141577
104TP53_16413492_ChIP-PET_HCT116_Human0.97476974
105TP53_18474530_ChIP-ChIP_U2OS_Human0.97084729
106HOXD13_18407260_ChIP-ChIP_DEVELOPING-LIMBS_Mouse0.96839563
107ZFP281_18757296_ChIP-ChIP_E14_Mouse0.96641989
108ER_23166858_ChIP-Seq_MCF-7_Human0.96428822
109JUN_21703547_ChIP-Seq_K562_Human0.95985685
110GATA1_26923725_Chip-Seq_HPCs_Mouse0.95683696
111DNAJC2_21179169_ChIP-ChIP_NT2_Human0.95672511
112TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.95540036
113TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.94582779
114POU5F1_26923725_Chip-Seq_MESODERM_Mouse0.94582779
115SMAD3_21741376_ChIP-Seq_ESCs_Human0.93949131
116PRDM14_20953172_ChIP-Seq_ESCs_Human0.93046563
117TRIM28_17542650_ChIP-ChIP_NTERA2_Human0.92662971
118SMAD4_21741376_ChIP-Seq_HESCs_Human0.92542204
119ZFP281_27345836_Chip-Seq_ESCs_Mouse0.92460795
120TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse0.91222155
121CEBPB_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.89438497
122TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse0.87572345
123ESR1_22446102_ChIP-Seq_UTERUS_Mouse0.86901336
124TFAP2C_20629094_ChIP-Seq_MCF-7_Human0.86866571
125VDR_22108803_ChIP-Seq_LS180_Human0.86790846
126BCAT_22108803_ChIP-Seq_LS180_Human0.86634012

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0004859_abnormal_synaptic_plasticity5.65080204
2MP0003880_abnormal_central_pattern4.66054792
3MP0003635_abnormal_synaptic_transmissio3.84387874
4MP0004270_analgesia3.54581230
5MP0002063_abnormal_learning/memory/cond3.13613891
6MP0009745_abnormal_behavioral_response3.11844829
7MP0005423_abnormal_somatic_nervous2.90283242
8MP0002064_seizures2.85994294
9MP0001968_abnormal_touch/_nociception2.81275340
10MP0009046_muscle_twitch2.77597874
11MP0002572_abnormal_emotion/affect_behav2.64194525
12MP0002734_abnormal_mechanical_nocicepti2.58730537
13MP0001486_abnormal_startle_reflex2.37817311
14MP0002272_abnormal_nervous_system2.33632092
15MP0000778_abnormal_nervous_system2.31976262
16MP0002822_catalepsy2.26557880
17MP0002735_abnormal_chemical_nociception2.20093384
18MP0002736_abnormal_nociception_after2.17274575
19MP0001440_abnormal_grooming_behavior2.11924182
20MP0009780_abnormal_chondrocyte_physiolo2.10955823
21MP0006276_abnormal_autonomic_nervous2.10108809
22MP0001501_abnormal_sleep_pattern2.02515423
23MP0002733_abnormal_thermal_nociception2.00769488
24MP0002184_abnormal_innervation2.00045388
25MP0002067_abnormal_sensory_capabilities1.92512617
26MP0003122_maternal_imprinting1.88878313
27MP0001970_abnormal_pain_threshold1.85909801
28MP0002557_abnormal_social/conspecific_i1.79220573
29MP0004924_abnormal_behavior1.77395862
30MP0005386_behavior/neurological_phenoty1.77395862
31MP0002909_abnormal_adrenal_gland1.74304340
32MP0003890_abnormal_embryonic-extraembry1.72997851
33MP0004811_abnormal_neuron_physiology1.72740016
34MP0003329_amyloid_beta_deposits1.68538337
35MP0004858_abnormal_nervous_system1.68446814
36MP0000955_abnormal_spinal_cord1.67478381
37MP0001529_abnormal_vocalization1.62418382
38MP0000566_synostosis1.57713315
39MP0005646_abnormal_pituitary_gland1.56542734
40MP0008569_lethality_at_weaning1.55717705
41MP0003787_abnormal_imprinting1.52604546
42MP0001984_abnormal_olfaction1.51783661
43MP0005645_abnormal_hypothalamus_physiol1.51176990
44MP0002882_abnormal_neuron_morphology1.48368653
45MP0003385_abnormal_body_wall1.45174445
46MP0003942_abnormal_urinary_system1.44958354
47MP0004885_abnormal_endolymph1.37581254
48MP0002066_abnormal_motor_capabilities/c1.37217841
49MP0010030_abnormal_orbit_morphology1.33043798
50MP0001905_abnormal_dopamine_level1.31270163
51MP0006292_abnormal_olfactory_placode1.28457938
52MP0003937_abnormal_limbs/digits/tail_de1.27802672
53MP0004133_heterotaxia1.26858598
54MP0000049_abnormal_middle_ear1.25671068
55MP0002233_abnormal_nose_morphology1.23596407
56MP0000569_abnormal_digit_pigmentation1.23558776
57MP0001188_hyperpigmentation1.23548945
58MP0002152_abnormal_brain_morphology1.22507993
59MP0003879_abnormal_hair_cell1.21027485
60MP0001502_abnormal_circadian_rhythm1.20809744
61MP0004142_abnormal_muscle_tone1.14113756
62MP0002938_white_spotting1.12591639
63MP0000751_myopathy1.10629199
64MP0003119_abnormal_digestive_system1.10451391
65MP0003633_abnormal_nervous_system1.10005491
66MP0003755_abnormal_palate_morphology1.08702424
67MP0000013_abnormal_adipose_tissue1.08589082
68MP0000631_abnormal_neuroendocrine_gland1.07925568
69MP0008789_abnormal_olfactory_epithelium1.07913378
70MP0005248_abnormal_Harderian_gland1.06716915
71MP0002837_dystrophic_cardiac_calcinosis1.05088606
72MP0010386_abnormal_urinary_bladder1.03089054
73MP0004742_abnormal_vestibular_system1.00573879
74MP0002697_abnormal_eye_size0.99270339
75MP0003631_nervous_system_phenotype0.98325779
76MP0004272_abnormal_basement_membrane0.97896529
77MP0009250_abnormal_appendicular_skeleto0.97658738
78MP0001293_anophthalmia0.97584144
79MP0005499_abnormal_olfactory_system0.97079383
80MP0005394_taste/olfaction_phenotype0.97079383
81MP0003283_abnormal_digestive_organ0.95862452
82MP0005623_abnormal_meninges_morphology0.94084827
83MP0005551_abnormal_eye_electrophysiolog0.94072070
84MP0003935_abnormal_craniofacial_develop0.93463824
85MP0002234_abnormal_pharynx_morphology0.93414103
86MP0002116_abnormal_craniofacial_bone0.92893440
87MP0003634_abnormal_glial_cell0.92878655
88MP0004145_abnormal_muscle_electrophysio0.92655304
89MP0002069_abnormal_eating/drinking_beha0.91790373
90MP0003938_abnormal_ear_development0.91192608
91MP0009384_cardiac_valve_regurgitation0.91183158
92MP0001177_atelectasis0.90615907
93MP0002081_perinatal_lethality0.90429740
94MP0001299_abnormal_eye_distance/0.89846611
95MP0002752_abnormal_somatic_nervous0.87708557
96MP0004085_abnormal_heartbeat0.87146363
97MP0001286_abnormal_eye_development0.86906996
98MP0000462_abnormal_digestive_system0.86688543
99MP0003121_genomic_imprinting0.86142358
100MP0002229_neurodegeneration0.85838515
101MP0005257_abnormal_intraocular_pressure0.85684846
102MP0008438_abnormal_cutaneous_collagen0.85303919
103MP0002249_abnormal_larynx_morphology0.83997813
104MP0001963_abnormal_hearing_physiology0.81967455
105MP0003861_abnormal_nervous_system0.81222330
106MP0005503_abnormal_tendon_morphology0.80239337
107MP0000639_abnormal_adrenal_gland0.78804945
108MP0003315_abnormal_perineum_morphology0.77935348
109MP0003632_abnormal_nervous_system0.77037254
110MP0005187_abnormal_penis_morphology0.76620936
111MP0003011_delayed_dark_adaptation0.75272436
112MP0003567_abnormal_fetal_cardiomyocyte0.75137285
113MP0002653_abnormal_ependyma_morphology0.72733556
114MP0003137_abnormal_impulse_conducting0.72681767
115MP0005195_abnormal_posterior_eye0.72286543
116MP0005409_darkened_coat_color0.70454898
117MP0006072_abnormal_retinal_apoptosis0.69649687
118MP0002638_abnormal_pupillary_reflex0.68431013
119MP0002090_abnormal_vision0.67863744
120MP0003690_abnormal_glial_cell0.67477732
121MP0008872_abnormal_physiological_respon0.67373149
122MP0000920_abnormal_myelination0.67136602
123MP0001943_abnormal_respiration0.66618699
124MP0004215_abnormal_myocardial_fiber0.65434632
125MP0005535_abnormal_body_temperature0.65363104
126MP0000534_abnormal_ureter_morphology0.65041491
127MP0008961_abnormal_basal_metabolism0.64973522
128MP0000537_abnormal_urethra_morphology0.64863693
129MP0004233_abnormal_muscle_weight0.64510908
130MP0000026_abnormal_inner_ear0.61083868
131MP0002751_abnormal_autonomic_nervous0.60920826
132MP0001485_abnormal_pinna_reflex0.60110766
133MP0008874_decreased_physiological_sensi0.58489367
134MP0003123_paternal_imprinting0.58256838
135MP0002876_abnormal_thyroid_physiology0.57840507
136MP0001664_abnormal_digestion0.57820698
137MP0000604_amyloidosis0.57287893

Predicted human phenotypes

RankGene SetZ-score
1Focal motor seizures (HP:0011153)6.44516798
2Myokymia (HP:0002411)5.60546549
3Focal seizures (HP:0007359)5.14853591
4Visual hallucinations (HP:0002367)4.55450180
5Epileptic encephalopathy (HP:0200134)4.34586084
6Atonic seizures (HP:0010819)4.19342921
7Progressive cerebellar ataxia (HP:0002073)3.89774974
8Febrile seizures (HP:0002373)3.78355597
9Absence seizures (HP:0002121)3.63556231
10Supranuclear gaze palsy (HP:0000605)3.44295727
11Broad-based gait (HP:0002136)3.38993756
12Dialeptic seizures (HP:0011146)3.34641733
13Generalized tonic-clonic seizures (HP:0002069)3.34563069
14Action tremor (HP:0002345)3.22742795
15Ankle clonus (HP:0011448)3.19389072
16Hyperventilation (HP:0002883)3.18505725
17Limb dystonia (HP:0002451)3.03787306
18Mutism (HP:0002300)2.99636752
19Drooling (HP:0002307)2.98688141
20Excessive salivation (HP:0003781)2.98688141
21Cerebral inclusion bodies (HP:0100314)2.88744960
22Impaired vibration sensation in the lower limbs (HP:0002166)2.85399162
23Poor eye contact (HP:0000817)2.85297217
24Amblyopia (HP:0000646)2.85122680
25Neurofibrillary tangles (HP:0002185)2.81806686
26Insidious onset (HP:0003587)2.79087121
27Termporal pattern (HP:0011008)2.79087121
28Truncal ataxia (HP:0002078)2.78708720
29Abnormal eating behavior (HP:0100738)2.77982959
30Depression (HP:0000716)2.75567477
31Abnormality of the corticospinal tract (HP:0002492)2.69676676
32Anxiety (HP:0000739)2.67025239
33Papilledema (HP:0001085)2.65604565
34Urinary bladder sphincter dysfunction (HP:0002839)2.64987845
35Progressive inability to walk (HP:0002505)2.64664680
36Dysdiadochokinesis (HP:0002075)2.61412506
37Gaze-evoked nystagmus (HP:0000640)2.61236928
38Impaired social interactions (HP:0000735)2.58472083
39Abnormal social behavior (HP:0012433)2.58472083
40Hemiparesis (HP:0001269)2.58162657
41Polyphagia (HP:0002591)2.55266793
42Epileptiform EEG discharges (HP:0011182)2.50142940
43Pheochromocytoma (HP:0002666)2.49273152
44Dysmetria (HP:0001310)2.47013538
45Genetic anticipation (HP:0003743)2.45399105
46Amyotrophic lateral sclerosis (HP:0007354)2.45162145
47Agitation (HP:0000713)2.44113403
48EEG with generalized epileptiform discharges (HP:0011198)2.43606963
49Urinary urgency (HP:0000012)2.42223980
50Spastic gait (HP:0002064)2.42122872
51Hepatoblastoma (HP:0002884)2.36488174
52Torticollis (HP:0000473)2.35473150
53Megalencephaly (HP:0001355)2.34156413
54Abnormality of the lower motor neuron (HP:0002366)2.32909206
55Hypsarrhythmia (HP:0002521)2.32146720
56Cortical dysplasia (HP:0002539)2.30169550
57Abnormality of binocular vision (HP:0011514)2.27151640
58Diplopia (HP:0000651)2.27151640
59Absent speech (HP:0001344)2.26586141
60Lower limb muscle weakness (HP:0007340)2.21654395
61Postural instability (HP:0002172)2.19101261
62Fetal akinesia sequence (HP:0001989)2.18960171
63Scanning speech (HP:0002168)2.16255542
64Neuroendocrine neoplasm (HP:0100634)2.13275042
65Focal dystonia (HP:0004373)2.11875025
66Stereotypic behavior (HP:0000733)2.11655762
67Hypoventilation (HP:0002791)2.11366442
68Impaired smooth pursuit (HP:0007772)2.03304112
69Akinesia (HP:0002304)2.02345754
70Cutaneous finger syndactyly (HP:0010554)2.01457184
71Pachygyria (HP:0001302)2.00973696
72Bradykinesia (HP:0002067)2.00884677
73Gait imbalance (HP:0002141)2.00430569
74Shawl scrotum (HP:0000049)1.99624523
75Abnormality of salivation (HP:0100755)1.99282962
76Inability to walk (HP:0002540)1.97563166
77Abnormality of the aortic arch (HP:0012303)1.96652128
78Aplasia/Hypoplasia of the brainstem (HP:0007362)1.95895309
79Hypoplasia of the brainstem (HP:0002365)1.95895309
80Inappropriate behavior (HP:0000719)1.95397803
81Intention tremor (HP:0002080)1.94792432
82Cutaneous syndactyly (HP:0012725)1.93922945
83Aqueductal stenosis (HP:0002410)1.93855420
84Atrophy/Degeneration involving the corticospinal tracts (HP:0007372)1.92608038
85Degeneration of the lateral corticospinal tracts (HP:0002314)1.92608038
86Renovascular hypertension (HP:0100817)1.91637572
87Craniofacial dystonia (HP:0012179)1.91463020
88Blue irides (HP:0000635)1.89793521
89Protruding tongue (HP:0010808)1.86713343
90Hyperthyroidism (HP:0000836)1.86299935
91Failure to thrive in infancy (HP:0001531)1.85089943
92Specific learning disability (HP:0001328)1.83541120
93Elevated circulating parathyroid hormone (PTH) level (HP:0003165)1.83475488
94Insomnia (HP:0100785)1.83013608
95Hemiplegia (HP:0002301)1.82600655
96Exotropia (HP:0000577)1.81785375
97Renal duplication (HP:0000075)1.81429461
98Aplasia involving bones of the upper limbs (HP:0009823)1.80175851
99Aplasia of the phalanges of the hand (HP:0009802)1.80175851
100Aplasia involving bones of the extremities (HP:0009825)1.80175851
101Abnormality of ocular smooth pursuit (HP:0000617)1.78977041
102Oligodactyly (hands) (HP:0001180)1.77440973
103Generalized myoclonic seizures (HP:0002123)1.77429516
104Morphological abnormality of the middle ear (HP:0008609)1.76175731
105Lower limb amyotrophy (HP:0007210)1.75619993
106Lissencephaly (HP:0001339)1.75182374
107Gait ataxia (HP:0002066)1.74681388
108Pointed chin (HP:0000307)1.74144062
109Shoulder girdle muscle weakness (HP:0003547)1.73708168
110Vaginal atresia (HP:0000148)1.73523400
111Neuronal loss in central nervous system (HP:0002529)1.73419617
112Incomplete penetrance (HP:0003829)1.73084625
113Vertebral arch anomaly (HP:0008438)1.72913500
114Genital tract atresia (HP:0001827)1.72206828
115Overgrowth (HP:0001548)1.71619773
116Anophthalmia (HP:0000528)1.71611597
117Myelomeningocele (HP:0002475)1.70007608
118Vitreoretinal degeneration (HP:0000655)1.65448323
119Labial hypoplasia (HP:0000066)1.62403807
120Diastasis recti (HP:0001540)1.58917493
121Abnormality of dentin (HP:0010299)1.58471516
122Elfin facies (HP:0004428)1.57805529
123Bladder diverticulum (HP:0000015)1.57538807
124Partial agenesis of the corpus callosum (HP:0001338)1.55955738
125Micropenis (HP:0000054)1.55931788
126Sleep apnea (HP:0010535)1.55480832
127Wide anterior fontanel (HP:0000260)1.54909993
128Neonatal short-limb short stature (HP:0008921)1.54290633
129Turricephaly (HP:0000262)1.53331408
130Congenital primary aphakia (HP:0007707)1.52798124
131Abnormality of the labia minora (HP:0012880)1.50684802
132Limited hip movement (HP:0008800)1.50104825
133Bowel diverticulosis (HP:0005222)1.49813564
134Overriding aorta (HP:0002623)1.49741596
135Rib fusion (HP:0000902)1.49527037
136Coronal craniosynostosis (HP:0004440)1.49345107
137Abnormal pancreas size (HP:0012094)1.49029646
138Poor suck (HP:0002033)1.47571233
139Spastic tetraplegia (HP:0002510)1.47267903
140High anterior hairline (HP:0009890)1.47033398
141Bronchomalacia (HP:0002780)1.45664935
142Infantile muscular hypotonia (HP:0008947)1.43986842
143Medial flaring of the eyebrow (HP:0010747)1.43967987
144Nephrogenic diabetes insipidus (HP:0009806)1.43750198
145Pulmonic stenosis (HP:0001642)1.43483085
146Oligodactyly (HP:0012165)1.42068907
147Shallow orbits (HP:0000586)1.41718057
148Osteomalacia (HP:0002749)1.41673976
149Short 4th metacarpal (HP:0010044)1.41320039
150Aplasia/Hypoplasia of the 4th metacarpal (HP:0010042)1.41320039
151Hypoplastic female external genitalia (HP:0012815)1.41270844
152Omphalocele (HP:0001539)1.40790933
153Papillary thyroid carcinoma (HP:0002895)1.39551039
154Abnormality of the diencephalon (HP:0010662)1.39027324
155Anomalous pulmonary venous return (HP:0010772)1.38435741
156Aplasia/Hypoplasia of the pubic bone (HP:0009104)1.38190829
157Precocious puberty (HP:0000826)1.38067440
158Protrusio acetabuli (HP:0003179)1.38056964
159Bifid tongue (HP:0010297)1.37914030
160Abnormality of the ischium (HP:0003174)1.37828312

Predicted kinase interactions (KEA)

RankGene SetZ-score
1MARK14.58727681
2NTRK34.04070517
3EPHA43.58798374
4MAP3K93.43843833
5MAP3K43.11008527
6MINK12.67171857
7MAP2K72.56808737
8CASK2.52453588
9NTRK22.33887740
10DAPK22.06348844
11PAK62.03997733
12PNCK1.96757943
13NTRK11.82642595
14MAP3K121.81903036
15MAP2K41.76691837
16MAPK131.75036958
17KSR11.67500709
18PLK21.63190754
19KSR21.59954858
20TNIK1.53125405
21CDK51.51580233
22PRKD31.40448829
23PHKG21.36774579
24PHKG11.36774579
25CAMKK11.35882703
26SIK21.35504446
27UHMK11.33428984
28LATS21.29044754
29GRK51.21423727
30LATS11.18921875
31ICK1.18793918
32DAPK11.18505851
33PDGFRA1.16989228
34AKT31.13414643
35RIPK41.13284320
36PRKCG1.12935416
37CDK191.08037787
38PAK31.03653091
39PRPF4B1.02872327
40CAMK2A1.02346347
41TYRO31.01551895
42CAMK1D0.99914635
43CSNK1G20.98942404
44CDK180.97179918
45CDK140.96779198
46CAMKK20.96047760
47CDK150.95074815
48EPHA30.94650927
49SGK4940.94177710
50SGK2230.94177710
51STK38L0.93837680
52MAP3K20.92734566
53ARAF0.91527917
54ERBB30.89440401
55PINK10.87817495
56FES0.87364008
57CAMK2B0.85890532
58OXSR10.82853901
59DYRK1A0.82469920
60CDK11A0.82046928
61DYRK1B0.81482408
62RET0.81229257
63STK380.81029654
64CAMK1G0.80952172
65DYRK20.79372295
66MARK20.77274134
67DMPK0.76493411
68CSNK1E0.74216518
69RIPK10.74116460
70STK110.72716439
71WNK30.71929583
72PKN20.71709312
73LMTK20.71445150
74BCR0.69436583
75PRKCH0.68546077
76PTK20.68004974
77PTK2B0.67862333
78DYRK30.65605945
79LIMK10.64940278
80CAMK10.64853110
81PRKCE0.64755429
82TRIM280.64316942
83SGK10.64271669
84SGK20.63902486
85FER0.62770452
86PKN10.59514308
87BRD40.59462445
88CSNK1G10.59392624
89TAOK10.58181460
90ERBB20.57475453
91DDR20.56940190
92PRKAA10.56413643
93PRKCZ0.55763999
94FGFR20.54897583
95CAMK40.54894065
96CSNK1G30.54643358
97CDC42BPA0.54284016
98FGR0.53897590
99WNK10.51595223
100CAMK2D0.50943563
101BMPR20.50609482
102STK390.50205553
103ROCK20.49429287
104PIK3CA0.48693063
105MKNK20.48003794
106RAF10.47826654
107FYN0.47622854
108FGFR10.46631203
109RPS6KA20.46624535
110CSNK1D0.46423407
111SGK30.46225737
112EPHB20.45647594
113NEK20.45626245
114RPS6KA30.44539458
115MAP2K10.44069017
116CSNK1A1L0.42751041
117MAP3K130.41862759
118BMPR1B0.41495765
119PDGFRB0.41259502
120PAK20.41055594
121EEF2K0.40941468
122MAPK100.40770679
123ALK0.40342287
124MTOR0.40148914
125ADRBK10.39766580
126ROCK10.39161200
127SCYL20.39066854
128WNK40.38806507
129NME10.38542454
130MAP3K60.38366024
131CAMK2G0.36975699

Predicted pathways (KEGG)

RankGene SetZ-score
1Nicotine addiction_Homo sapiens_hsa050333.69387937
2Synaptic vesicle cycle_Homo sapiens_hsa047213.12691615
3GABAergic synapse_Homo sapiens_hsa047272.69327657
4Retrograde endocannabinoid signaling_Homo sapiens_hsa047232.63930181
5Circadian entrainment_Homo sapiens_hsa047132.56793132
6Long-term potentiation_Homo sapiens_hsa047202.45394045
7Glutamatergic synapse_Homo sapiens_hsa047242.44300076
8Morphine addiction_Homo sapiens_hsa050322.44155585
9Olfactory transduction_Homo sapiens_hsa047402.42894776
10Amphetamine addiction_Homo sapiens_hsa050312.35001426
11Steroid biosynthesis_Homo sapiens_hsa001002.27764509
12Dopaminergic synapse_Homo sapiens_hsa047282.22088251
13Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049612.06743199
14Salivary secretion_Homo sapiens_hsa049701.96899283
15Insulin secretion_Homo sapiens_hsa049111.91800439
16Cholinergic synapse_Homo sapiens_hsa047251.89449162
17Taste transduction_Homo sapiens_hsa047421.85259073
18Cocaine addiction_Homo sapiens_hsa050301.80840408
19Serotonergic synapse_Homo sapiens_hsa047261.78797151
20Long-term depression_Homo sapiens_hsa047301.75967043
21Renin secretion_Homo sapiens_hsa049241.75369157
22Gastric acid secretion_Homo sapiens_hsa049711.72609021
23Aldosterone synthesis and secretion_Homo sapiens_hsa049251.68896188
24Vasopressin-regulated water reabsorption_Homo sapiens_hsa049621.68447569
25Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042611.60886290
26Oxytocin signaling pathway_Homo sapiens_hsa049211.56875800
27Axon guidance_Homo sapiens_hsa043601.54972361
28Collecting duct acid secretion_Homo sapiens_hsa049661.54447612
29Gap junction_Homo sapiens_hsa045401.47602250
30Calcium signaling pathway_Homo sapiens_hsa040201.43269746
31GnRH signaling pathway_Homo sapiens_hsa049121.39434382
32Basal cell carcinoma_Homo sapiens_hsa052171.38563873
33Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010401.36129535
34Terpenoid backbone biosynthesis_Homo sapiens_hsa009001.30558535
35Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047501.22932994
36Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005341.22740200
37Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049601.20487848
38Estrogen signaling pathway_Homo sapiens_hsa049151.18909684
39cAMP signaling pathway_Homo sapiens_hsa040241.18787360
40Vibrio cholerae infection_Homo sapiens_hsa051101.17901001
41Type II diabetes mellitus_Homo sapiens_hsa049301.17451185
42Butanoate metabolism_Homo sapiens_hsa006501.14212657
43Melanogenesis_Homo sapiens_hsa049161.13460080
44Neuroactive ligand-receptor interaction_Homo sapiens_hsa040801.11516677
45Glioma_Homo sapiens_hsa052141.10444361
46ErbB signaling pathway_Homo sapiens_hsa040121.06566700
47ECM-receptor interaction_Homo sapiens_hsa045121.05955869
48Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045501.04098409
49Cardiac muscle contraction_Homo sapiens_hsa042601.03368190
50cGMP-PKG signaling pathway_Homo sapiens_hsa040220.99866691
51Vascular smooth muscle contraction_Homo sapiens_hsa042700.92218483
52Phosphatidylinositol signaling system_Homo sapiens_hsa040700.91363759
53Phototransduction_Homo sapiens_hsa047440.90933321
54Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.88385653
55Ascorbate and aldarate metabolism_Homo sapiens_hsa000530.87714566
56Oocyte meiosis_Homo sapiens_hsa041140.87110154
57Propanoate metabolism_Homo sapiens_hsa006400.85510546
58Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001300.85333979
59Dilated cardiomyopathy_Homo sapiens_hsa054140.84552048
60Dorso-ventral axis formation_Homo sapiens_hsa043200.83015805
61Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049640.82868208
62Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.80291291
63Phospholipase D signaling pathway_Homo sapiens_hsa040720.78970328
64Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.77704095
65Thyroid hormone synthesis_Homo sapiens_hsa049180.75416623
66Adherens junction_Homo sapiens_hsa045200.74870068
67Bile secretion_Homo sapiens_hsa049760.74716933
68Protein digestion and absorption_Homo sapiens_hsa049740.72246302
69MAPK signaling pathway_Homo sapiens_hsa040100.71614663
70Pancreatic secretion_Homo sapiens_hsa049720.71490266
71Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.70944850
72Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.70455259
73Fatty acid metabolism_Homo sapiens_hsa012120.70199337
74Lysine degradation_Homo sapiens_hsa003100.68617877
75Alcoholism_Homo sapiens_hsa050340.68019123
76Choline metabolism in cancer_Homo sapiens_hsa052310.67839834
77Valine, leucine and isoleucine degradation_Homo sapiens_hsa002800.67470593
78AMPK signaling pathway_Homo sapiens_hsa041520.66512207
79Pyruvate metabolism_Homo sapiens_hsa006200.66334933
80Focal adhesion_Homo sapiens_hsa045100.65874063
81Ras signaling pathway_Homo sapiens_hsa040140.63919092
82Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054120.63621161
83Wnt signaling pathway_Homo sapiens_hsa043100.62883871
84Fatty acid biosynthesis_Homo sapiens_hsa000610.61832705
85Alzheimers disease_Homo sapiens_hsa050100.60909924
86Endometrial cancer_Homo sapiens_hsa052130.60742814
87Neurotrophin signaling pathway_Homo sapiens_hsa047220.60462556
88Renal cell carcinoma_Homo sapiens_hsa052110.60032429
89Rap1 signaling pathway_Homo sapiens_hsa040150.59263325
90beta-Alanine metabolism_Homo sapiens_hsa004100.58605528
91Taurine and hypotaurine metabolism_Homo sapiens_hsa004300.57993849
92Steroid hormone biosynthesis_Homo sapiens_hsa001400.55848655
93Synthesis and degradation of ketone bodies_Homo sapiens_hsa000720.55046630
94Glucagon signaling pathway_Homo sapiens_hsa049220.54921408
95Maturity onset diabetes of the young_Homo sapiens_hsa049500.54315018
96VEGF signaling pathway_Homo sapiens_hsa043700.53220219
97Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.53126213
98Arginine and proline metabolism_Homo sapiens_hsa003300.52364172
99Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.51974816
100Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.51803560
101Sphingolipid signaling pathway_Homo sapiens_hsa040710.51438199
102Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.51266485
103Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.51012111
104TGF-beta signaling pathway_Homo sapiens_hsa043500.50977926
105Carbohydrate digestion and absorption_Homo sapiens_hsa049730.50427976
106Fatty acid degradation_Homo sapiens_hsa000710.50017684
107Protein export_Homo sapiens_hsa030600.49799874
108Ovarian steroidogenesis_Homo sapiens_hsa049130.49626514
109Fat digestion and absorption_Homo sapiens_hsa049750.49017958
110Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004000.48555095
111Thyroid hormone signaling pathway_Homo sapiens_hsa049190.48380231
112Prion diseases_Homo sapiens_hsa050200.48179023
113mTOR signaling pathway_Homo sapiens_hsa041500.47635482
114Colorectal cancer_Homo sapiens_hsa052100.47164395
115Hedgehog signaling pathway_Homo sapiens_hsa043400.45551064
116Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054100.45464560
117Endocytosis_Homo sapiens_hsa041440.45066467
118Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.44715215
119Oxidative phosphorylation_Homo sapiens_hsa001900.44424827
120Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.43826037
121Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.43793439
122Insulin signaling pathway_Homo sapiens_hsa049100.43777592
123Type I diabetes mellitus_Homo sapiens_hsa049400.43371993
124PI3K-Akt signaling pathway_Homo sapiens_hsa041510.43230960
125Longevity regulating pathway - mammal_Homo sapiens_hsa042110.42276576
126Circadian rhythm_Homo sapiens_hsa047100.40129603
127Non-small cell lung cancer_Homo sapiens_hsa052230.36635486
128Parkinsons disease_Homo sapiens_hsa050120.35812097
129Tight junction_Homo sapiens_hsa045300.34329694
130Inositol phosphate metabolism_Homo sapiens_hsa005620.30547487
131Hippo signaling pathway_Homo sapiens_hsa043900.30516473
132SNARE interactions in vesicular transport_Homo sapiens_hsa041300.29794727
133Melanoma_Homo sapiens_hsa052180.29309552

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