TAT

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: This nuclear gene encodes a mitochondrial protein tyrosine aminotransferase which is present in the liver and catalyzes the conversion of L-tyrosine into p-hydroxyphenylpyruvate. Mutations in this gene cause tyrosinemia (type II, Richner-Hanhart syndrome), a disorder accompanied by major skin and corneal lesions, with possible mental retardation. A regulator gene for tyrosine aminotransferase is X-linked. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1omega-hydroxylase P450 pathway (GO:0097267)9.50737056
2epoxygenase P450 pathway (GO:0019373)9.26440349
3* L-phenylalanine catabolic process (GO:0006559)7.46619752
4* erythrose 4-phosphate/phosphoenolpyruvate family amino acid catabolic process (GO:1902222)7.46619752
5* erythrose 4-phosphate/phosphoenolpyruvate family amino acid metabolic process (GO:1902221)7.10268101
6* L-phenylalanine metabolic process (GO:0006558)7.10268101
7* aromatic amino acid family catabolic process (GO:0009074)6.80512481
8drug metabolic process (GO:0017144)6.59435421
9oxidative demethylation (GO:0070989)6.38365346
10tryptophan catabolic process (GO:0006569)6.29051957
11indole-containing compound catabolic process (GO:0042436)6.29051957
12indolalkylamine catabolic process (GO:0046218)6.29051957
13triglyceride-rich lipoprotein particle remodeling (GO:0034370)6.25876767
14kynurenine metabolic process (GO:0070189)6.11995121
15bile acid biosynthetic process (GO:0006699)5.99712057
16urea metabolic process (GO:0019627)5.91071896
17urea cycle (GO:0000050)5.91071896
18tryptophan metabolic process (GO:0006568)5.90905568
19glyoxylate metabolic process (GO:0046487)5.73763312
20negative regulation of fibrinolysis (GO:0051918)5.60700805
21S-adenosylmethionine metabolic process (GO:0046500)5.59970637
22alpha-linolenic acid metabolic process (GO:0036109)5.57754509
23high-density lipoprotein particle remodeling (GO:0034375)5.52504160
24complement activation, alternative pathway (GO:0006957)5.44469369
25ethanol metabolic process (GO:0006067)5.43610638
26nitrogen cycle metabolic process (GO:0071941)5.43370407
27cysteine metabolic process (GO:0006534)5.41603327
28regulation of protein activation cascade (GO:2000257)5.40836308
29regulation of fibrinolysis (GO:0051917)5.40573677
30sulfur amino acid catabolic process (GO:0000098)5.39356907
31peptidyl-glutamic acid carboxylation (GO:0017187)5.38372170
32protein carboxylation (GO:0018214)5.38372170
33regulation of plasminogen activation (GO:0010755)5.37587042
34serine family amino acid catabolic process (GO:0009071)5.22643640
35bile acid metabolic process (GO:0008206)5.12873735
36phenylpropanoid metabolic process (GO:0009698)5.07187583
37opsonization (GO:0008228)5.06395360
38regulation of complement activation (GO:0030449)5.05386261
39homocysteine metabolic process (GO:0050667)4.98097231
40* aromatic amino acid family metabolic process (GO:0009072)4.88213329
41regulation of triglyceride catabolic process (GO:0010896)4.85723127
42fatty acid beta-oxidation using acyl-CoA oxidase (GO:0033540)4.85034567
43regulation of cholesterol esterification (GO:0010872)4.81848636
44reverse cholesterol transport (GO:0043691)4.80387896
45acute-phase response (GO:0006953)4.77412801
46killing of cells in other organism involved in symbiotic interaction (GO:0051883)4.74238691
47disruption of cells of other organism involved in symbiotic interaction (GO:0051818)4.74238691
48plasma lipoprotein particle remodeling (GO:0034369)4.73819266
49protein-lipid complex remodeling (GO:0034368)4.73819266
50macromolecular complex remodeling (GO:0034367)4.73819266
51* alpha-amino acid catabolic process (GO:1901606)4.67703267
52regulation of humoral immune response (GO:0002920)4.67659172
53amino-acid betaine metabolic process (GO:0006577)4.64635141
54lysine metabolic process (GO:0006553)4.62331959
55lysine catabolic process (GO:0006554)4.62331959
56triglyceride homeostasis (GO:0070328)4.61746419
57acylglycerol homeostasis (GO:0055090)4.61746419
58alkaloid metabolic process (GO:0009820)4.56367269
59negative regulation of cholesterol transport (GO:0032375)4.55006785
60negative regulation of sterol transport (GO:0032372)4.55006785
61negative regulation of blood coagulation (GO:0030195)4.52821571
62negative regulation of hemostasis (GO:1900047)4.52821571
63phospholipid efflux (GO:0033700)4.51477815
64glycine metabolic process (GO:0006544)4.46524333
65coenzyme catabolic process (GO:0009109)4.45908635
66negative regulation of protein activation cascade (GO:2000258)4.45648167
67indolalkylamine metabolic process (GO:0006586)4.45004030
68bile acid and bile salt transport (GO:0015721)4.43580014
69imidazole-containing compound metabolic process (GO:0052803)4.40874727
70cellular biogenic amine catabolic process (GO:0042402)4.36642294
71amine catabolic process (GO:0009310)4.36642294
72cellular ketone body metabolic process (GO:0046950)4.34468589
73flavonoid metabolic process (GO:0009812)4.33042261
74plasma lipoprotein particle clearance (GO:0034381)4.31991444
75* tyrosine metabolic process (GO:0006570)4.29932712
76* cellular amino acid catabolic process (GO:0009063)4.29416921
77cellular glucuronidation (GO:0052695)4.26796405
78serine family amino acid metabolic process (GO:0009069)4.23816835
79cholesterol efflux (GO:0033344)4.18488195
80benzene-containing compound metabolic process (GO:0042537)4.15193474
81arginine metabolic process (GO:0006525)4.14434639
82cellular modified amino acid catabolic process (GO:0042219)4.10702756
83negative regulation of coagulation (GO:0050819)4.09875325
84dicarboxylic acid biosynthetic process (GO:0043650)4.07481588
85ethanol oxidation (GO:0006069)4.06558365
86negative regulation of wound healing (GO:0061045)4.06038484
87serine family amino acid biosynthetic process (GO:0009070)4.05651670
88* glutamate metabolic process (GO:0006536)4.03489504
89fibrinolysis (GO:0042730)4.02075751
90positive regulation of heterotypic cell-cell adhesion (GO:0034116)4.00003010
91aldehyde catabolic process (GO:0046185)3.99096160
92low-density lipoprotein particle remodeling (GO:0034374)3.96896764
93plasma lipoprotein particle assembly (GO:0034377)3.94734812
94drug catabolic process (GO:0042737)3.94564943
95intestinal cholesterol absorption (GO:0030299)3.90858608
96positive regulation of blood coagulation (GO:0030194)3.90681337
97positive regulation of hemostasis (GO:1900048)3.90681337
98heme transport (GO:0015886)3.85774447
99blood coagulation, intrinsic pathway (GO:0007597)3.83527145
100regulation of bile acid biosynthetic process (GO:0070857)3.82234670
101complement activation, classical pathway (GO:0006958)3.82203578
102cofactor catabolic process (GO:0051187)3.82049837
103uronic acid metabolic process (GO:0006063)3.78237069
104glucuronate metabolic process (GO:0019585)3.78237069
105complement activation (GO:0006956)3.77891709
106negative regulation of lipase activity (GO:0060192)3.77786137
107ketone body metabolic process (GO:1902224)3.75949402
108phospholipid homeostasis (GO:0055091)3.75574035
109protein activation cascade (GO:0072376)3.74533067
110cholesterol homeostasis (GO:0042632)3.74427635
111* organic acid catabolic process (GO:0016054)3.74323747
112* carboxylic acid catabolic process (GO:0046395)3.74323747
113positive regulation of lipoprotein lipase activity (GO:0051006)3.73838766
114positive regulation of triglyceride lipase activity (GO:0061365)3.73838766
115acetyl-CoA metabolic process (GO:0006084)3.73252093
116very-low-density lipoprotein particle assembly (GO:0034379)3.72973814
117cytolysis (GO:0019835)3.72726161
118positive regulation of lipid catabolic process (GO:0050996)3.71431426
119hormone catabolic process (GO:0042447)3.71038887
120sterol homeostasis (GO:0055092)3.68257682
121regulation of cholesterol homeostasis (GO:2000188)3.67784897
122negative regulation of complement activation (GO:0045916)3.62253343
123short-chain fatty acid metabolic process (GO:0046459)3.62190943
124xenobiotic metabolic process (GO:0006805)3.61066544
125plasma lipoprotein particle organization (GO:0071827)3.58583589
126positive regulation of coagulation (GO:0050820)3.58329537
127NAD biosynthetic process (GO:0009435)3.57562261
128protein-lipid complex assembly (GO:0065005)3.53538376
129nicotinamide nucleotide biosynthetic process (GO:0019359)3.53536619
130acute inflammatory response (GO:0002526)3.53326457
131positive regulation of fatty acid biosynthetic process (GO:0045723)3.45081816
132regulation of apoptotic cell clearance (GO:2000425)3.39057221
133exogenous drug catabolic process (GO:0042738)10.2373254

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1* RXR_22158963_ChIP-Seq_LIVER_Mouse8.43317990
2* PPARA_22158963_ChIP-Seq_LIVER_Mouse7.20370511
3* EGR1_23403033_ChIP-Seq_LIVER_Mouse7.00210596
4* LXR_22158963_ChIP-Seq_LIVER_Mouse6.52097014
5FOXO1_23066095_ChIP-Seq_LIVER_Mouse5.41281581
6CEBPA_23403033_ChIP-Seq_LIVER_Mouse5.17997853
7PPARG_19300518_ChIP-PET_3T3-L1_Mouse4.78614254
8CEBPB_23403033_ChIP-Seq_LIVER_Mouse4.06414063
9* NR1I2_20693526_ChIP-Seq_LIVER_Mouse4.03798660
10* TCF7L2_21901280_ChIP-Seq_H4IIE_Rat2.06023774
11* ESR1_17901129_ChIP-ChIP_LIVER_Mouse12.0112665
12TAF7L_23326641_ChIP-Seq_C3H10T1-2_Mouse1.97456072
13HNF4A_19761587_ChIP-ChIP_CACO-2_Human1.96575765
14FOXA2_19822575_ChIP-Seq_HepG2_Human1.60734206
15CLOCK_20551151_ChIP-Seq_293T_Human1.57184613
16HTT_18923047_ChIP-ChIP_STHdh_Human1.55910345
17GATA1_22025678_ChIP-Seq_K562_Human1.45795965
18* HNF4A_19822575_ChIP-Seq_HepG2_Human1.40472500
19THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse1.28068138
20STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse1.25027775
21RXRA_24833708_ChIP-Seq_LIVER_Mouse1.19783753
22STAT5_23275557_ChIP-Seq_MAMMARY-EPITHELIUM_Mouse1.17518324
23IGF1R_20145208_ChIP-Seq_DFB_Human1.08601103
24ESR1_15608294_ChIP-ChIP_MCF-7_Human1.07708760
25ETS2_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse1.01513690
26NFE2_27457419_Chip-Seq_LIVER_Mouse1.01286538
27IRF1_21803131_ChIP-Seq_MONOCYTES_Human0.95438767
28PIAS1_25552417_ChIP-Seq_VCAP_Human0.95348875
29ER_23166858_ChIP-Seq_MCF-7_Human0.93371487
30SOX2_27498859_Chip-Seq_STOMACH_Mouse0.92964848
31PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse0.92439156
32CDX2_21074721_ChIP-Seq_CACO-2_Mouse0.90826103
33TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse0.90170305
34HNFA_21074721_ChIP-Seq_CACO-2_Human0.89028903
35IRF1_19129219_ChIP-ChIP_H3396_Human0.88529510
36PHF8_20622853_ChIP-Seq_HELA_Human0.88228683
37MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human0.86616198
38ETV2_25802403_ChIP-Seq_MESCs_Mouse0.85649509
39TP53_18474530_ChIP-ChIP_U2OS_Human0.84597743
40AUTS2_25519132_ChIP-Seq_293T-REX_Human0.84255391
41EZH2_27294783_Chip-Seq_NPCs_Mouse0.84131421
42IRF8_22096565_ChIP-ChIP_GC-B_Human0.81256884
43POU3F2_20337985_ChIP-ChIP_501MEL_Human0.81220082
44RARG_19884340_ChIP-ChIP_MEFs_Mouse0.80467804
45SOX2_21211035_ChIP-Seq_LN229_Human0.79863388
46ZNF652_21678463_ChIP-ChIP_ZR75-1_Human0.79843809
47NFYA_21822215_ChIP-Seq_K562_Human0.79841827
48SREBP1_19666523_ChIP-Seq_LIVER_Mouse0.79789829
49GATA4_25053715_ChIP-Seq_YYC3_Human0.79600584
50PPARD_23176727_ChIP-Seq_KERATINOCYTES_Mouse0.79297098
51ESRRB_18555785_ChIP-Seq_MESCs_Mouse0.77993673
52KAP1_22055183_ChIP-Seq_ESCs_Mouse0.77003748
53SUZ12_27294783_Chip-Seq_NPCs_Mouse0.76476322
54GATA6_21074721_ChIP-Seq_CACO-2_Mouse0.76292861
55ZNF263_19887448_ChIP-Seq_K562_Human0.75704100
56* RAC3_21632823_ChIP-Seq_H3396_Human0.75318721
57SREBP2_21459322_ChIP-Seq_LIVER_Mouse0.74763502
58RARA_24833708_ChIP-Seq_LIVER_Mouse0.74709000
59FOXA1_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human0.73404101
60Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse0.71887223
61GATA6_21074721_ChIP-Seq_CACO-2_Human0.71839397
62* BACH1_22875853_ChIP-PCR_HELA_AND_SCP4_Human0.71680491
63* MYC_19829295_ChIP-Seq_ESCs_Human0.71297020
64CEBPB_21427703_ChIP-Seq_3T3-L1_Mouse0.70900345
65PCGF2_27294783_Chip-Seq_NPCs_Mouse0.70237808
66SPI1_20517297_ChIP-Seq_HL60_Human0.70104061
67SOX2_19829295_ChIP-Seq_ESCs_Human0.69480948
68NANOG_19829295_ChIP-Seq_ESCs_Human0.69480948
69SALL4_18804426_ChIP-ChIP_XEN_Mouse0.69063201
70CTNNB1_24651522_ChIP-Seq_LGR5+_INTESTINAL_STEM_Human0.68070335
71CRX_20693478_ChIP-Seq_RETINA_Mouse0.68052047
72GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse0.67035454
73EBNA1_20929547_Chip-Seq_RAJI-cells_Human0.66479805
74* AR_21915096_ChIP-Seq_LNCaP-1F5_Human0.66367316
75AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human0.65720898
76ESR2_21235772_ChIP-Seq_MCF-7_Human0.65680891
77CBX2_22325352_ChIP-Seq_293T-Rex_Human0.65420623
78GBX2_23144817_ChIP-Seq_PC3_Human0.64810448
79RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human0.64610990
80TRIM28_21343339_ChIP-Seq_HEK293_Human0.64517667
81GATA2_20887958_ChIP-Seq_HPC-7_Mouse0.64127736
82RARB_24833708_ChIP-Seq_LIVER_Mouse0.64021102
83OCT4_20526341_ChIP-Seq_ESCs_Human0.63135995
84NFE2L2_20460467_ChIP-Seq_MEFs_Mouse0.63061801
85NRF2_20460467_ChIP-Seq_MEFs_Mouse0.63061801
86OCT4_21477851_ChIP-Seq_ESCs_Mouse0.62848328
87KLF5_20875108_ChIP-Seq_MESCs_Mouse0.62516977
88CTBP1_25329375_ChIP-Seq_LNCAP_Human0.62174175
89ETV1_20927104_ChIP-Seq_GIST48_Human0.62069011
90FOXH1_21741376_ChIP-Seq_EPCs_Human0.61887666
91NR0B1_18358816_ChIP-ChIP_MESCs_Mouse0.61727130
92EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human0.61101169
93* CDX2_22108803_ChIP-Seq_LS180_Human0.61077300
94NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human0.60982891
95BMI1_19503595_ChIP-Seq_MEFsC_Mouse0.60015624
96RAD21_21589869_ChIP-Seq_MESCs_Mouse0.59541069
97FOXA1_25329375_ChIP-Seq_VCAP_Human0.58604963
98FOXA1_27270436_Chip-Seq_PROSTATE_Human0.58604963
99STAT3_23295773_ChIP-Seq_U87_Human0.57474602
100E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse0.57422359
101E2F1_20622854_ChIP-Seq_HELA_Human0.56121228
102PCGF4_22325352_ChIP-Seq_293T-Rex_Human0.55796608
103GATA3_21878914_ChIP-Seq_MCF-7_Human0.55738084
104NR4A2_19515692_ChIP-ChIP_MN9D_Mouse0.55695900
105SMAD4_21741376_ChIP-Seq_EPCs_Human0.55560489
106OCT4_18555785_Chip-Seq_ESCs_Mouse0.55293625
107* CEBPB_22108803_ChIP-Seq_LS180_Human0.54121067
108FOXA1_25552417_ChIP-Seq_VCAP_Human0.53995507
109STAT3_1855785_ChIP-Seq_MESCs_Mouse0.53029400
110FOXA1_21915096_ChIP-Seq_LNCaP-1F5_Human0.52829801
111AR_20517297_ChIP-Seq_VCAP_Human0.52540214
112EGR1_19032775_ChIP-ChIP_M12_Human0.51655964
113FOXA1_26743006_Chip-Seq_LNCaP-abl_Human0.51540753
114LXR_22292898_ChIP-Seq_THP-1_Human0.51524852
115PBX_27287812_Chip-Seq_EMBYONIC-LIMB_Mouse0.51278272
116MYC_19915707_ChIP-ChIP_AK7_Human0.50026362
117ESET_19884257_ChIP-Seq_ESCs_Mouse0.48212922
118CBP_21632823_ChIP-Seq_H3396_Human0.48040253
119P53_21459846_ChIP-Seq_SAOS-2_Human0.46921438
120STAT1_17558387_ChIP-Seq_HELA_Human0.46525841
121TAF15_26573619_Chip-Seq_HEK293_Human0.46309170
122PPARG_20887899_ChIP-Seq_3T3-L1_Mouse0.46186193
123ESR1_21235772_ChIP-Seq_MCF-7_Human0.45532523
124PPARD_23208498_ChIP-Seq_MDA-MB-231_Human0.43848696
125CDX2_20551321_ChIP-Seq_CACO-2_Human0.43835917
126FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse0.43298647
127PBX1_22567123_ChIP-ChIP_OVCAR3_Human0.42339129
128FOXA1_26769127_Chip-Seq_PDAC-Cell_line_Human0.42237492
129TAF2_19829295_ChIP-Seq_ESCs_Human0.41162959
130SRY_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse0.40674690
131FOXO3_23340844_ChIP-Seq_DLD1_Human0.40339409
132CDX2_21402776_ChIP-Seq_INTESTINAL-VILLUS_Mouse0.39699394
133GATA1_19941826_ChIP-Seq_K562_Human0.39277376
134GATA6_25053715_ChIP-Seq_YYC3_Human0.39190246
135GATA1_19941827_ChIP-Seq_MEL_Mouse0.38454617
136PPAR_26484153_Chip-Seq_NCI-H1993_Human0.38228266
137GATA2_19941826_ChIP-Seq_K562_Human0.37757088
138ERG_21242973_ChIP-ChIP_JURKAT_Human0.37732426
139BCAT_22108803_ChIP-Seq_LS180_Human0.37394016
140STAT3_19079543_ChIP-ChIP_MESCs_Mouse0.36815426
141LUZP1_20508642_ChIP-Seq_ESCs_Mouse0.35736634
142SOX6_21985497_ChIP-Seq_MYOTUBES_Mouse0.35297749
143NCOR_22424771_ChIP-Seq_293T_Human0.34675395
144SPI1_26923725_Chip-Seq_HPCs_Mouse0.34583020
145* MYC_27129775_Chip-Seq_CORNEA_Mouse0.34575001
146ERG_20517297_ChIP-Seq_VCAP_Human0.34007852
147GLI1_17442700_ChIP-ChIP_MESCs_Mouse0.33974750
148ESR1_20079471_ChIP-ChIP_T-47D_Human0.33761500
149GATA3_20176728_ChIP-ChIP_TSCs_Mouse0.33540654
150CEBPB_26923725_Chip-Seq_MACROPHAGESS_Mouse0.33454195

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0002139_abnormal_hepatobiliary_system8.25776723
2MP0005360_urolithiasis7.55168787
3MP0005085_abnormal_gallbladder_physiolo6.51611676
4MP0005365_abnormal_bile_salt6.19329668
5MP0008875_abnormal_xenobiotic_pharmacok5.18246286
6MP0003806_abnormal_nucleotide_metabolis4.26219221
7MP0003252_abnormal_bile_duct3.93862751
8MP0010329_abnormal_lipoprotein_level3.57107826
9MP0009840_abnormal_foam_cell3.30102746
10MP0005083_abnormal_biliary_tract3.02429984
11MP0003195_calcinosis2.86642315
12MP0005332_abnormal_amino_acid2.80125211
13MP0001666_abnormal_nutrient_absorption2.59751966
14MP0003191_abnormal_cellular_cholesterol2.30408017
15MP0000609_abnormal_liver_physiology2.17341474
16MP0004019_abnormal_vitamin_homeostasis2.14665585
17MP0002118_abnormal_lipid_homeostasis2.10679140
18MP0002138_abnormal_hepatobiliary_system2.00113994
19MP0003868_abnormal_feces_composition1.97749388
20MP0005319_abnormal_enzyme/_coenzyme1.83849826
21MP0001764_abnormal_homeostasis1.68844955
22MP0009697_abnormal_copulation1.58455927
23MP0005584_abnormal_enzyme/coenzyme_acti1.56418894
24MP0005451_abnormal_body_composition1.44158234
25MP0003011_delayed_dark_adaptation1.36620525
26MP0003186_abnormal_redox_activity1.26622867
27MP0003656_abnormal_erythrocyte_physiolo1.23596267
28MP0009643_abnormal_urine_homeostasis1.23177482
29MP0000598_abnormal_liver_morphology1.18969571
30MP0003879_abnormal_hair_cell1.17269550
31MP0003705_abnormal_hypodermis_morpholog1.15535359
32MP0005647_abnormal_sex_gland1.12614526
33MP0000604_amyloidosis1.05623924
34MP0009764_decreased_sensitivity_to1.04647518
35MP0009763_increased_sensitivity_to1.02395871
36MP0002132_abnormal_respiratory_system1.01816564
37MP0002254_reproductive_system_inflammat1.01409839
38MP0005670_abnormal_white_adipose0.97497539
39MP0010368_abnormal_lymphatic_system0.90944279
40MP0005636_abnormal_mineral_homeostasis0.90850565
41MP0008469_abnormal_protein_level0.88534342
42MP0009642_abnormal_blood_homeostasis0.87025219
43MP0005408_hypopigmentation0.85265312
44MP0006036_abnormal_mitochondrial_physio0.80955998
45MP0005376_homeostasis/metabolism_phenot0.79991752
46MP0009765_abnormal_xenobiotic_induced0.79216273
47MP0002282_abnormal_trachea_morphology0.78420296
48MP0002078_abnormal_glucose_homeostasis0.78318375
49MP0002876_abnormal_thyroid_physiology0.76435684
50MP0005084_abnormal_gallbladder_morpholo0.74315301
51MP0005220_abnormal_exocrine_pancreas0.74114459
52MP0002971_abnormal_brown_adipose0.73533563
53MP0005334_abnormal_fat_pad0.69553644
54MP0001661_extended_life_span0.69177925
55MP0004130_abnormal_muscle_cell0.68247424
56MP0003690_abnormal_glial_cell0.66948819
57MP0005535_abnormal_body_temperature0.66884251
58MP0005266_abnormal_metabolism0.65586848
59MP0009053_abnormal_anal_canal0.64528341
60MP0003646_muscle_fatigue0.63897838
61MP0001915_intracranial_hemorrhage0.62089344
62MP0003329_amyloid_beta_deposits0.62013399
63MP0005187_abnormal_penis_morphology0.61818542
64MP0001756_abnormal_urination0.60044167
65MP0002249_abnormal_larynx_morphology0.59652251
66MP0000639_abnormal_adrenal_gland0.59472368
67MP0003136_yellow_coat_color0.57539057
68MP0006035_abnormal_mitochondrial_morpho0.56718400
69MP0005448_abnormal_energy_balance0.54985692
70MP0003045_fibrosis0.52560969
71MP0005464_abnormal_platelet_physiology0.51483055
72MP0005395_other_phenotype0.49879819
73MP0003718_maternal_effect0.49282718
74MP0002822_catalepsy0.48349442
75MP0009785_altered_susceptibility_to0.47242119
76MP0003638_abnormal_response/metabolism_0.45996140
77MP0008873_increased_physiological_sensi0.45710139
78MP0008874_decreased_physiological_sensi0.45373853
79MP0002928_abnormal_bile_duct0.45019721
80MP0002653_abnormal_ependyma_morphology0.44017840
81MP0002136_abnormal_kidney_physiology0.43990875
82MP0003436_decreased_susceptibility_to0.42929499
83MP0002332_abnormal_exercise_endurance0.42681597
84MP0002837_dystrophic_cardiac_calcinosis0.42042158
85MP0003724_increased_susceptibility_to0.41428317
86MP0004782_abnormal_surfactant_physiolog0.41352627
87MP0005666_abnormal_adipose_tissue0.41207996
88MP0004381_abnormal_hair_follicle0.40607658
89MP0003953_abnormal_hormone_level0.40565703
90MP0005248_abnormal_Harderian_gland0.40144583
91MP0003075_altered_response_to0.38294473
92MP0005171_absent_coat_pigmentation0.37791865
93MP0000579_abnormal_nail_morphology0.37714309
94MP0009672_abnormal_birth_weight0.37573962
95MP0005166_decreased_susceptibility_to0.37316513
96MP0008872_abnormal_physiological_respon0.36568582
97MP0003890_abnormal_embryonic-extraembry0.35026255
98MP0009384_cardiac_valve_regurgitation0.33951804
99MP0009115_abnormal_fat_cell0.32710701
100MP0002796_impaired_skin_barrier0.32169605
101MP0001243_abnormal_dermal_layer0.32127664
102MP0000230_abnormal_systemic_arterial0.31582266
103MP0002970_abnormal_white_adipose0.31567996
104MP0002168_other_aberrant_phenotype0.31092611
105MP0005023_abnormal_wound_healing0.30915365
106MP0000249_abnormal_blood_vessel0.30903375
107MP0001853_heart_inflammation0.30075621
108MP0004883_abnormal_blood_vessel0.29199320
109MP0001881_abnormal_mammary_gland0.28888488
110MP0001986_abnormal_taste_sensitivity0.27843755
111MP0001845_abnormal_inflammatory_respons0.27309821
112MP0006082_CNS_inflammation0.27223079
113MP0000566_synostosis0.26563323
114MP0004142_abnormal_muscle_tone0.25975276
115MP0002090_abnormal_vision0.25414745
116MP0002060_abnormal_skin_morphology0.25255537
117MP0005164_abnormal_response_to0.23523800
118MP0000427_abnormal_hair_cycle0.23505103
119MP0000467_abnormal_esophagus_morphology0.23110535
120MP0005377_hearing/vestibular/ear_phenot0.21812687
121MP0003878_abnormal_ear_physiology0.21812687

Predicted human phenotypes

RankGene SetZ-score
1Deep venous thrombosis (HP:0002625)7.43634251
2Intrahepatic cholestasis (HP:0001406)7.32917586
3* Abnormality of aromatic amino acid family metabolism (HP:0004338)7.05849501
4Prolonged partial thromboplastin time (HP:0003645)6.60673570
5Hypobetalipoproteinemia (HP:0003563)6.49590403
6* Abnormality of monocarboxylic acid metabolism (HP:0010996)6.47895103
7Xanthomatosis (HP:0000991)6.34946888
8Hyperlipoproteinemia (HP:0010980)5.67778673
9Complement deficiency (HP:0004431)5.50164123
10Hypolipoproteinemia (HP:0010981)4.82934488
11Joint hemorrhage (HP:0005261)4.77278775
12Hyperammonemia (HP:0001987)4.67888074
13Epidermoid cyst (HP:0200040)4.63028005
14Abnormality of the common coagulation pathway (HP:0010990)4.48840297
15Hyperglycinemia (HP:0002154)4.45395956
16Abnormality of methionine metabolism (HP:0010901)4.44742877
17Abnormality of the level of lipoprotein cholesterol (HP:0010979)4.42893557
18Abnormality of sulfur amino acid metabolism (HP:0004339)4.36271714
19Ketosis (HP:0001946)4.26771393
20Abnormality of glutamine family amino acid metabolism (HP:0010902)4.26334687
21Abnormality of aspartate family amino acid metabolism (HP:0010899)4.24135080
22Hypoalphalipoproteinemia (HP:0003233)4.21076841
23Fat malabsorption (HP:0002630)4.11797846
24Abnormality of pyrimidine metabolism (HP:0004353)4.01588486
25Abnormality of complement system (HP:0005339)4.00961696
26Hyperglycinuria (HP:0003108)3.92197545
27Abnormality of glycine metabolism (HP:0010895)3.91348820
28Abnormality of serine family amino acid metabolism (HP:0010894)3.91348820
29Hypoglycemic coma (HP:0001325)3.84761123
30Conjugated hyperbilirubinemia (HP:0002908)3.78887974
31Abnormality of the intrinsic pathway (HP:0010989)3.78197184
32Hypercholesterolemia (HP:0003124)3.63865922
33Abnormality of long-chain fatty-acid metabolism (HP:0010964)3.36860152
34Hyperbilirubinemia (HP:0002904)3.32746350
35Abnormality of fatty-acid metabolism (HP:0004359)3.30483782
36Abnormality of serum amino acid levels (HP:0003112)3.14753113
37Abnormality of nucleobase metabolism (HP:0010932)3.12461196
38Steatorrhea (HP:0002570)3.09989672
39Delayed CNS myelination (HP:0002188)3.07792196
40Spontaneous abortion (HP:0005268)3.07157678
41Hepatocellular carcinoma (HP:0001402)3.00420600
42Ketoacidosis (HP:0001993)2.98876904
43Myocardial infarction (HP:0001658)2.97819137
44Hypochromic microcytic anemia (HP:0004840)2.92036883
45Skin nodule (HP:0200036)2.88082126
46Neonatal hypoglycemia (HP:0001998)2.77660674
47Systemic lupus erythematosus (HP:0002725)2.75823092
48Fair hair (HP:0002286)2.74391183
49Metabolic acidosis (HP:0001942)2.74299368
50Abnormality of purine metabolism (HP:0004352)2.67897551
51Lethargy (HP:0001254)2.63610772
52Purpura (HP:0000979)2.58930407
53Vascular calcification (HP:0004934)2.55263071
54Abnormality of dicarboxylic acid metabolism (HP:0010995)2.54185422
55Dicarboxylic aciduria (HP:0003215)2.54185422
56Acanthocytosis (HP:0001927)2.53741755
57Gout (HP:0001997)2.53140680
58Spastic diplegia (HP:0001264)2.48966914
59Glomerulonephritis (HP:0000099)2.48274101
60Hypoglycemic seizures (HP:0002173)2.47974015
61Cerebral edema (HP:0002181)2.47808210
62Pulmonary embolism (HP:0002204)2.46430062
63Abnormal gallbladder morphology (HP:0012437)2.46427692
64Mitral stenosis (HP:0001718)2.44360585
65Irritability (HP:0000737)2.42816187
66Osteomalacia (HP:0002749)2.38947124
67Cholelithiasis (HP:0001081)2.38899167
68Neonatal onset (HP:0003623)2.38608744
69Recurrent gram-negative bacterial infections (HP:0005420)2.38487019
70Abnormal gallbladder physiology (HP:0012438)2.34459012
71Cholecystitis (HP:0001082)2.34459012
72Amyloidosis (HP:0011034)2.29394431
73Cardiovascular calcification (HP:0011915)2.26016269
74Gingival bleeding (HP:0000225)2.21692564
75Esophageal varix (HP:0002040)2.19066244
76Malnutrition (HP:0004395)2.18700105
77Pancreatitis (HP:0001733)2.14605469
78Menorrhagia (HP:0000132)2.14139786
79Enlarged kidneys (HP:0000105)2.13430878
80Late onset (HP:0003584)2.12957638
81Brushfield spots (HP:0001088)2.12895994
82Sensorimotor neuropathy (HP:0007141)2.11524863
83Thrombophlebitis (HP:0004418)2.08444786
84Gangrene (HP:0100758)2.08105514
85Reduced antithrombin III activity (HP:0001976)2.06795218
86Vomiting (HP:0002013)2.06691270
87Hyperinsulinemic hypoglycemia (HP:0000825)2.02920633
88Arthropathy (HP:0003040)2.02666792
89Opisthotonus (HP:0002179)2.01347089
90Generalized aminoaciduria (HP:0002909)2.00699464
91Abnormality of the gallbladder (HP:0005264)2.00033271
92Poikilocytosis (HP:0004447)1.97912990
93Hemorrhage of the eye (HP:0011885)1.95360862
94Generalized hypopigmentation of hair (HP:0011358)1.93911370
95Rickets (HP:0002748)1.92252896
96Alkalosis (HP:0001948)1.90475593
97Abnormal cartilage morphology (HP:0002763)1.90193931
98Abnormality of iron homeostasis (HP:0011031)1.89653737
99Joint swelling (HP:0001386)1.89456892
100Abnormality of transition element cation homeostasis (HP:0011030)1.86534245
101Cerebral palsy (HP:0100021)1.85190612
102Renal cortical cysts (HP:0000803)1.84428215
103Hypophosphatemic rickets (HP:0004912)1.83451662
104Hydroxyprolinuria (HP:0003080)1.82958097
105Abnormality of proline metabolism (HP:0010907)1.82958097
106Abnormal enzyme/coenzyme activity (HP:0012379)1.82099077
107Elevated alkaline phosphatase (HP:0003155)1.82005467
108Hyperglycemia (HP:0003074)1.81607389
109Elevated hepatic transaminases (HP:0002910)1.81408199
110Status epilepticus (HP:0002133)1.81314822
111Hyperphosphaturia (HP:0003109)1.79108631
112Glycosuria (HP:0003076)1.77418513
113Abnormality of urine glucose concentration (HP:0011016)1.77418513
114Abnormality of vitamin metabolism (HP:0100508)1.75037956
115Nephritis (HP:0000123)1.74359261
116Atrioventricular block (HP:0001678)1.72627791
117Increased mean platelet volume (HP:0011877)1.71527985
118Epistaxis (HP:0000421)1.71461576
119Increased serum ferritin (HP:0003281)1.68099047
120Abnormality of the Achilles tendon (HP:0005109)1.67701426
121Abnormality of alkaline phosphatase activity (HP:0004379)1.66119626
122Bile duct proliferation (HP:0001408)1.58032777
123Abnormal biliary tract physiology (HP:0012439)1.58032777
124Blue irides (HP:0000635)1.57711236
125Potter facies (HP:0002009)1.56473246
126Facial shape deformation (HP:0011334)1.56473246
127Bifid scrotum (HP:0000048)1.55720960

Predicted kinase interactions (KEA)

RankGene SetZ-score
1BCKDK7.13672513
2FGFR44.63699381
3SIK14.52969895
4ERN14.52912871
5TAOK33.15642728
6INSRR3.10869820
7ERBB43.08837823
8NLK2.88455146
9STK382.51375617
10MAP2K42.36061514
11ACVR1B2.16230243
12PKN22.15250236
13MST1R2.08396709
14MAPK111.92087641
15FLT31.89476172
16PIK3CG1.76674082
17TRIB31.75017313
18LATS11.68276355
19TYK21.65720273
20ABL21.52455115
21ZAK1.48280061
22FRK1.48219999
23PTK61.45109305
24DAPK21.44045901
25NEK91.41392030
26FGFR21.40062291
27TNK21.39192977
28NTRK31.37422525
29JAK21.24371141
30KDR1.24197780
31BMPR1B1.18635164
32MAP3K71.18624867
33PRKAA21.15066761
34PINK11.14457985
35MAP3K21.11468353
36ERBB21.08309818
37MELK1.06519276
38GRK61.04229389
39TBK11.03139688
40FER1.02972088
41MAP2K31.02612110
42JAK11.02519733
43MAPK40.98828506
44MAP3K140.95631670
45MAPK150.94280348
46MAP3K100.92782739
47PRKCZ0.92308619
48STK38L0.86739443
49WNK30.86198130
50EPHA30.86028591
51EPHB10.85485485
52MET0.84944070
53MAP3K30.84433151
54PRKD30.80277497
55MAPK120.79490892
56CDK60.77470867
57PRKACA0.77221253
58PRKACG0.76815818
59CAMK2G0.75884997
60KSR20.75448696
61PRKG10.75433133
62ADRBK20.72526801
63MAP3K110.71340108
64STK30.70934237
65CAMKK20.70896635
66MAP2K60.69966193
67TIE10.68744452
68IRAK30.68376113
69PRKAA10.68362653
70CSK0.68048720
71DYRK1B0.68010991
72GSK3A0.67589078
73SGK30.66822963
74CAMK1D0.66354716
75PRPF4B0.65154463
76PDK20.61792736
77MAPK70.59718507
78FGFR30.59478721
79PTK20.55044066
80CSNK1D0.54926315
81CSF1R0.54067283
82RIPK10.54015297
83MYLK0.53082023
84GRK70.52987916
85IKBKE0.52889921
86CSNK1G10.52886547
87TGFBR20.50721373
88PDPK10.50336288
89PRKCQ0.48782881
90SGK20.48771122
91EPHA40.47153998
92MAP3K50.45556802
93IGF1R0.44277643
94TAOK20.43245900
95PKN10.43006956
96MAP2K10.42896376
97GRK10.42358095
98MAP3K130.41622105
99PRKCG0.41339752
100RET0.41131463
101PRKD10.39900338
102PRKCB0.39771863
103SGK10.39316290
104CDK40.38626977
105ADRBK10.38550044
106RPS6KA30.38053116
107PRKACB0.37966211
108MTOR0.37344184
109ICK0.37302795
110MAP3K60.37110202
111CAMKK10.34526994
112MAPKAPK30.33791583
113STK110.33694596
114EGFR0.33271477
115MAPK30.32833805
116CSNK1G20.32548594
117SGK2230.32221072
118SGK4940.32221072
119PBK0.32058795
120IRAK10.31329818
121CSNK1G30.29835111
122PDK10.29662773
123CAMK40.29658206
124WNK40.29565772
125MAP3K10.29386203
126CSNK1A10.28559672
127LATS20.27863736
128IRAK20.27455257
129MAP4K20.25903538
130PRKCA0.25869426
131CSNK1E0.25405755
132TLK10.23372874
133PRKCE0.22947124
134AKT20.22639582
135ABL10.22246495
136CSNK2A10.22082907
137AKT30.21934912
138KIT0.21881526
139PIK3CA0.21735853
140MAP2K20.21687540
141CSNK1A1L0.21195047
142PDK30.20770523

Predicted pathways (KEGG)

RankGene SetZ-score
1Primary bile acid biosynthesis_Homo sapiens_hsa001204.61716758
2Nitrogen metabolism_Homo sapiens_hsa009103.77040234
3Ascorbate and aldarate metabolism_Homo sapiens_hsa000533.38989999
4Arginine biosynthesis_Homo sapiens_hsa002203.23803296
5Complement and coagulation cascades_Homo sapiens_hsa046102.81766411
6Tryptophan metabolism_Homo sapiens_hsa003802.73743330
7Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010402.69321026
8* Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004002.67590667
9Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006302.64164904
10Glycine, serine and threonine metabolism_Homo sapiens_hsa002602.62570235
11Fatty acid degradation_Homo sapiens_hsa000712.48705335
12Valine, leucine and isoleucine degradation_Homo sapiens_hsa002802.39063514
13Pentose and glucuronate interconversions_Homo sapiens_hsa000402.28087907
14Drug metabolism - cytochrome P450_Homo sapiens_hsa009822.15811109
15Butanoate metabolism_Homo sapiens_hsa006502.13601074
16Peroxisome_Homo sapiens_hsa041462.09764854
17Steroid hormone biosynthesis_Homo sapiens_hsa001401.96188471
18Chemical carcinogenesis_Homo sapiens_hsa052041.96136237
19Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009801.93457136
20Histidine metabolism_Homo sapiens_hsa003401.93372834
21Propanoate metabolism_Homo sapiens_hsa006401.93018374
22PPAR signaling pathway_Homo sapiens_hsa033201.88515134
23Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002501.83956705
24Drug metabolism - other enzymes_Homo sapiens_hsa009831.81861481
25Caffeine metabolism_Homo sapiens_hsa002321.81486824
26Fatty acid metabolism_Homo sapiens_hsa012121.79647823
27Staphylococcus aureus infection_Homo sapiens_hsa051501.79042024
28beta-Alanine metabolism_Homo sapiens_hsa004101.72336085
29Retinol metabolism_Homo sapiens_hsa008301.71268143
30Pantothenate and CoA biosynthesis_Homo sapiens_hsa007701.69771345
31Selenocompound metabolism_Homo sapiens_hsa004501.63419504
322-Oxocarboxylic acid metabolism_Homo sapiens_hsa012101.57805688
33Synthesis and degradation of ketone bodies_Homo sapiens_hsa000721.54304655
34Bile secretion_Homo sapiens_hsa049761.50984097
35Pyruvate metabolism_Homo sapiens_hsa006201.37030426
36Sulfur metabolism_Homo sapiens_hsa009201.36364194
37Starch and sucrose metabolism_Homo sapiens_hsa005001.30937598
38Fatty acid elongation_Homo sapiens_hsa000621.30596021
39* Tyrosine metabolism_Homo sapiens_hsa003501.28671215
40* Phenylalanine metabolism_Homo sapiens_hsa003601.28540618
41* Cysteine and methionine metabolism_Homo sapiens_hsa002701.27350387
42Folate biosynthesis_Homo sapiens_hsa007901.25447598
43Steroid biosynthesis_Homo sapiens_hsa001001.22199595
44ABC transporters_Homo sapiens_hsa020101.21686535
45* Biosynthesis of amino acids_Homo sapiens_hsa012301.18999236
46Fat digestion and absorption_Homo sapiens_hsa049751.16321577
47Carbon metabolism_Homo sapiens_hsa012001.15056044
48Taurine and hypotaurine metabolism_Homo sapiens_hsa004301.07347926
49Maturity onset diabetes of the young_Homo sapiens_hsa049501.06042930
50* Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001301.00017011
51Cyanoamino acid metabolism_Homo sapiens_hsa004600.99228374
52Arginine and proline metabolism_Homo sapiens_hsa003300.98082285
53Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.97724276
54Sulfur relay system_Homo sapiens_hsa041220.95060917
55Vitamin B6 metabolism_Homo sapiens_hsa007500.94059527
56Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.89412508
57Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049640.87089857
58Vitamin digestion and absorption_Homo sapiens_hsa049770.85327003
59Lysine degradation_Homo sapiens_hsa003100.81650717
60One carbon pool by folate_Homo sapiens_hsa006700.78702445
61Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.71588854
62Glycerolipid metabolism_Homo sapiens_hsa005610.68346618
63Glutathione metabolism_Homo sapiens_hsa004800.64993478
64Pentose phosphate pathway_Homo sapiens_hsa000300.59400280
65Fatty acid biosynthesis_Homo sapiens_hsa000610.53160815
66Citrate cycle (TCA cycle)_Homo sapiens_hsa000200.50255284
67* Metabolic pathways_Homo sapiens_hsa011000.46978990
68Butirosin and neomycin biosynthesis_Homo sapiens_hsa005240.40742411
69Prion diseases_Homo sapiens_hsa050200.39758764
70Pertussis_Homo sapiens_hsa051330.32933766
71Galactose metabolism_Homo sapiens_hsa000520.26746180
72Fructose and mannose metabolism_Homo sapiens_hsa000510.26597018
73alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.25711468
74Insulin resistance_Homo sapiens_hsa049310.24977270
75Adipocytokine signaling pathway_Homo sapiens_hsa049200.23725949
76Linoleic acid metabolism_Homo sapiens_hsa005910.22813594
77Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.19877624
78Glycerophospholipid metabolism_Homo sapiens_hsa005640.18273814
79Glucagon signaling pathway_Homo sapiens_hsa049220.12324715
80Serotonergic synapse_Homo sapiens_hsa047260.06058854
81AMPK signaling pathway_Homo sapiens_hsa041520.04049035
82Sphingolipid metabolism_Homo sapiens_hsa006000.03409614
83Ether lipid metabolism_Homo sapiens_hsa00565-0.2504074
84Type II diabetes mellitus_Homo sapiens_hsa04930-0.2375134
85Amoebiasis_Homo sapiens_hsa05146-0.2337785
86Longevity regulating pathway - mammal_Homo sapiens_hsa04211-0.2300826
87Phototransduction_Homo sapiens_hsa04744-0.2279359
88Longevity regulating pathway - multiple species_Homo sapiens_hsa04213-0.2253146
89Carbohydrate digestion and absorption_Homo sapiens_hsa04973-0.2089248
90Thyroid hormone synthesis_Homo sapiens_hsa04918-0.1922238
91Renin-angiotensin system_Homo sapiens_hsa04614-0.1894129
92GABAergic synapse_Homo sapiens_hsa04727-0.1882833
93Hepatitis C_Homo sapiens_hsa05160-0.1777343
94Protein processing in endoplasmic reticulum_Homo sapiens_hsa04141-0.1726361
95Vascular smooth muscle contraction_Homo sapiens_hsa04270-0.1717315
96Circadian rhythm_Homo sapiens_hsa04710-0.1689641
97N-Glycan biosynthesis_Homo sapiens_hsa00510-0.1666513
98Arachidonic acid metabolism_Homo sapiens_hsa00590-0.1638237
99Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa00604-0.1624569
100Central carbon metabolism in cancer_Homo sapiens_hsa05230-0.1566381
101African trypanosomiasis_Homo sapiens_hsa05143-0.1519890
102Glycosaminoglycan degradation_Homo sapiens_hsa00531-0.1443460
103Systemic lupus erythematosus_Homo sapiens_hsa05322-0.1377162
104Other glycan degradation_Homo sapiens_hsa00511-0.1218600
105Mineral absorption_Homo sapiens_hsa04978-0.0888138
106Regulation of autophagy_Homo sapiens_hsa04140-0.0865456
107Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa00534-0.0842737
108Insulin signaling pathway_Homo sapiens_hsa04910-0.0832537
109Ovarian steroidogenesis_Homo sapiens_hsa04913-0.0651556
110Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932-0.0492388
111Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa00520-0.0468001

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