TAL1

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1oxygen transport (GO:0015671)9.36341736
2gas transport (GO:0015669)8.66551959
3porphyrin-containing compound biosynthetic process (GO:0006779)7.87388940
4heme biosynthetic process (GO:0006783)7.68678635
5tetrapyrrole biosynthetic process (GO:0033014)7.03268503
6ribosomal small subunit assembly (GO:0000028)6.51995694
7porphyrin-containing compound metabolic process (GO:0006778)6.12479135
8heme metabolic process (GO:0042168)5.92787725
9* erythrocyte maturation (GO:0043249)5.91998129
10erythrocyte development (GO:0048821)5.66713719
11viral transcription (GO:0019083)5.59216676
12* definitive hemopoiesis (GO:0060216)5.39374352
13translational termination (GO:0006415)5.38427689
14neutrophil activation involved in immune response (GO:0002283)4.92918050
15translational elongation (GO:0006414)4.66942396
16regulation of platelet aggregation (GO:0090330)4.50827802
17* erythrocyte differentiation (GO:0030218)4.48697231
18* embryonic hemopoiesis (GO:0035162)4.42711268
19negative regulation of erythrocyte differentiation (GO:0045647)4.42610582
20* myeloid cell development (GO:0061515)4.37858000
21endothelium development (GO:0003158)4.35660831
22SRP-dependent cotranslational protein targeting to membrane (GO:0006614)4.35328375
23nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184)4.32779313
24ribosomal small subunit biogenesis (GO:0042274)4.29618940
25hemoglobin metabolic process (GO:0020027)4.28244862
26protein targeting to ER (GO:0045047)4.24842634
27cotranslational protein targeting to membrane (GO:0006613)4.24128927
28DNA unwinding involved in DNA replication (GO:0006268)4.19858218
29iron ion import (GO:0097286)4.18654695
30cellular protein complex disassembly (GO:0043624)4.14418401
31maturation of SSU-rRNA (GO:0030490)4.11401666
32viral life cycle (GO:0019058)4.10956405
33* regulation of erythrocyte differentiation (GO:0045646)4.09060767
34establishment of protein localization to endoplasmic reticulum (GO:0072599)4.07442205
353-UTR-mediated mRNA stabilization (GO:0070935)4.06334218
36positive regulation of gamma-delta T cell activation (GO:0046645)3.97417864
37protein localization to endoplasmic reticulum (GO:0070972)3.95751827
38* megakaryocyte development (GO:0035855)3.95075874
39translational initiation (GO:0006413)3.94832994
40tetrapyrrole metabolic process (GO:0033013)3.92712024
41protein complex disassembly (GO:0043241)3.80824762
42response to methylmercury (GO:0051597)3.80000833
43platelet dense granule organization (GO:0060155)3.70589532
44response to insecticide (GO:0017085)3.67904573
45DNA strand elongation involved in DNA replication (GO:0006271)3.67477623
46DNA replication initiation (GO:0006270)3.59925209
47regulation of granulocyte differentiation (GO:0030852)3.56821474
48DNA strand elongation (GO:0022616)3.55384360
49* granulocyte differentiation (GO:0030851)3.54109532
50negative regulation of viral entry into host cell (GO:0046597)3.53112869
51regulation of platelet activation (GO:0010543)3.52726301
52telomere maintenance via semi-conservative replication (GO:0032201)3.51133162
53macromolecular complex disassembly (GO:0032984)3.51103830
54pigment biosynthetic process (GO:0046148)3.49760418
55platelet aggregation (GO:0070527)3.38109632
56regulation of DNA endoreduplication (GO:0032875)3.34352669
57regulation of transcription involved in G1/S transition of mitotic cell cycle (GO:0000083)3.31835342
58regulation of mast cell degranulation (GO:0043304)3.31447989
59nuclear-transcribed mRNA catabolic process (GO:0000956)3.29385858
60IMP biosynthetic process (GO:0006188)3.29361478
61response to lead ion (GO:0010288)3.28780440
62* positive regulation of erythrocyte differentiation (GO:0045648)3.27418526
63innate immune response in mucosa (GO:0002227)3.27368424
64positive regulation of mast cell activation (GO:0033005)3.21412355
65purine-containing compound salvage (GO:0043101)3.18509977
66protein localization to chromosome, centromeric region (GO:0071459)3.17332195
67protein localization to kinetochore (GO:0034501)3.14702605
68mRNA catabolic process (GO:0006402)3.14250048
69neutrophil activation (GO:0042119)3.11851837
70regulation of mast cell activation involved in immune response (GO:0033006)3.11304441
71positive regulation of B cell differentiation (GO:0045579)3.10878730
72secretory granule organization (GO:0033363)3.10219239
73regulation of response to osmotic stress (GO:0047484)3.10202537
74RNA catabolic process (GO:0006401)3.09889816
75regulation of megakaryocyte differentiation (GO:0045652)3.08992886
76negative regulation of RNA splicing (GO:0033119)3.08096862
77regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:00450913.06744041
78adenosine receptor signaling pathway (GO:0001973)3.04642290
79DNA topological change (GO:0006265)3.04548561
80positive regulation of vasculogenesis (GO:2001214)3.00180715
81deoxyribonucleoside monophosphate metabolic process (GO:0009162)2.99636634
82positive regulation of megakaryocyte differentiation (GO:0045654)2.99098304
83histamine secretion (GO:0001821)2.97991531
84DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 cla2.97973407
85thrombin receptor signaling pathway (GO:0070493)2.95762902
86autophagic vacuole fusion (GO:0000046)2.94974125
87angiogenesis involved in wound healing (GO:0060055)2.94425457
88cellular response to thyroid hormone stimulus (GO:0097067)2.94280334
89positive regulation of hematopoietic progenitor cell differentiation (GO:1901534)2.93373542
90granulocyte activation (GO:0036230)2.93302529
91leukocyte migration involved in inflammatory response (GO:0002523)2.91796401
92telomere maintenance via recombination (GO:0000722)2.91658433
93poly(A)+ mRNA export from nucleus (GO:0016973)2.91372114
94regulation of histone H3-K9 methylation (GO:0051570)2.90854003
95response to arsenic-containing substance (GO:0046685)2.89281402
96mucosal-associated lymphoid tissue development (GO:0048537)2.89235591
97Peyers patch development (GO:0048541)2.89235591
98pigment metabolic process (GO:0042440)2.86341021
99regulation of mast cell activation (GO:0033003)2.85668552
100G-protein coupled purinergic nucleotide receptor signaling pathway (GO:0035589)2.85166681
101IMP metabolic process (GO:0046040)2.84568228
102protein targeting to membrane (GO:0006612)2.84204380
103antibacterial humoral response (GO:0019731)2.84017887
104leukocyte degranulation (GO:0043299)2.83280870
105nerve growth factor signaling pathway (GO:0038180)2.82584176
106cellular response to arsenic-containing substance (GO:0071243)2.81430411
107regulation of gamma-delta T cell differentiation (GO:0045586)2.79194640
108folic acid-containing compound biosynthetic process (GO:0009396)2.78424033
109hepatocyte apoptotic process (GO:0097284)2.78345780
110organelle membrane fusion (GO:0090174)2.77711765
111response to peptidoglycan (GO:0032494)2.77166001
112blood vessel maturation (GO:0001955)2.76552753
113alternative mRNA splicing, via spliceosome (GO:0000380)2.76245394
114response to thyroid hormone (GO:0097066)2.75886453
115mitotic recombination (GO:0006312)2.75489080
116regulation of RNA export from nucleus (GO:0046831)2.75252783
117sister chromatid segregation (GO:0000819)2.74454260
118DNA damage response, signal transduction resulting in transcription (GO:0042772)2.72436741
119antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G2.71939112
120regulation of myeloid leukocyte mediated immunity (GO:0002886)2.71256618
121lipopolysaccharide biosynthetic process (GO:0009103)2.71048682
122negative regulation of histone methylation (GO:0031061)2.70992005
123glycine transport (GO:0015816)2.70703693
124regulation of hypersensitivity (GO:0002883)2.70492211
125ribosomal large subunit biogenesis (GO:0042273)2.68953844
126mitotic sister chromatid segregation (GO:0000070)2.68793334
127negative regulation of mRNA splicing, via spliceosome (GO:0048025)2.68500428
128chromatin assembly (GO:0031497)2.68248037
129positive regulation of granulocyte differentiation (GO:0030854)2.66981418
130kinetochore organization (GO:0051383)2.66931270
131one-carbon compound transport (GO:0019755)2.65886679
132negative regulation of norepinephrine secretion (GO:0010700)2.64853531
133regulation of histone H3-K4 methylation (GO:0051569)2.64203726
134N-terminal protein amino acid acetylation (GO:0006474)2.63778587
135T cell homeostasis (GO:0043029)2.62593911
136DNA replication checkpoint (GO:0000076)2.62244948
137translesion synthesis (GO:0019985)2.61924155
138CD4-positive or CD8-positive, alpha-beta T cell lineage commitment (GO:0043369)2.61507657
139* platelet formation (GO:0030220)2.59659964
140negative regulation of amyloid precursor protein catabolic process (GO:1902992)2.59600891
141* hemopoiesis (GO:0030097)2.59453103
142antigen processing and presentation via MHC class Ib (GO:0002475)2.57151369
143chromatin assembly or disassembly (GO:0006333)2.53787695
144mucosal immune response (GO:0002385)2.53280424
145antimicrobial humoral response (GO:0019730)2.51397751
146positive regulation of mast cell activation involved in immune response (GO:0033008)2.50669856
147positive regulation of mast cell degranulation (GO:0043306)2.50669856
148negative regulation of focal adhesion assembly (GO:0051895)2.50227506
149negative regulation of cell junction assembly (GO:1901889)2.50227506
150negative regulation of adherens junction organization (GO:1903392)2.50227506
151ether lipid metabolic process (GO:0046485)2.49029480
152telomere maintenance via telomere lengthening (GO:0010833)2.48300290
153positive regulation of bone resorption (GO:0045780)2.47822305
154positive regulation of bone remodeling (GO:0046852)2.47822305
155regulation of B cell differentiation (GO:0045577)2.47557333
156regulation of inositol phosphate biosynthetic process (GO:0010919)2.46857017
157Arp2/3 complex-mediated actin nucleation (GO:0034314)2.46284088
158regulation of integrin activation (GO:0033623)2.45074322
159modulation by virus of host process (GO:0019054)2.44359619
160protoporphyrinogen IX metabolic process (GO:0046501)11.1653725
161protoporphyrinogen IX biosynthetic process (GO:0006782)10.2933973

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1E2F7_22180533_ChIP-Seq_HELA_Human7.99216214
2EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse5.06394440
3* SCL_19346495_ChIP-Seq_HPC-7_Human4.60945672
4FOXM1_23109430_ChIP-Seq_U2OS_Human3.90024092
5GATA1_22025678_ChIP-Seq_K562_Human3.84441446
6SCL_21571218_ChIP-Seq_MEGAKARYOCYTES_Human3.19313931
7E2F4_17652178_ChIP-ChIP_JURKAT_Human3.16355237
8TAL1_20566737_ChIP-Seq_PRIMARY_FETAL_LIVER_ERYTHROID_Mouse3.10103621
9MYC_18555785_ChIP-Seq_MESCs_Mouse2.82279383
10* GATA1_19941826_ChIP-Seq_K562_Human2.73533531
11GATA1_19941827_ChIP-Seq_MEL_Mouse2.70634868
12MYC_22102868_ChIP-Seq_BL_Human2.61393843
13MECOM_23826213_ChIP-Seq_KASUMI_Mouse2.57590187
14* TAL1_20887958_ChIP-Seq_HPC-7_Mouse2.54733877
15FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human2.49735736
16SPI1_23127762_ChIP-Seq_K562_Human2.48419152
17* GATA1_22383799_ChIP-Seq_G1ME_Mouse2.41237590
18SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse2.31936655
19VDR_21846776_ChIP-Seq_THP-1_Human2.24978246
20SOX9_22984422_ChIP-ChIP_TESTIS_Rat2.22572587
21BP1_19119308_ChIP-ChIP_Hs578T_Human2.05995640
22RUNX1_20887958_ChIP-Seq_HPC-7_Mouse2.03536278
23ELF1_17652178_ChIP-ChIP_JURKAT_Human1.96835249
24EGR1_19374776_ChIP-ChIP_THP-1_Human1.93318541
25KLF1_20508144_ChIP-Seq_FETAL-LIVER-ERYTHROID_Mouse1.93276939
26E2F1_21310950_ChIP-Seq_MCF-7_Human1.85591839
27MYC_19079543_ChIP-ChIP_MESCs_Mouse1.81538869
28MYC_18358816_ChIP-ChIP_MESCs_Mouse1.77655032
29MYC_19030024_ChIP-ChIP_MESCs_Mouse1.76195049
30MYB_21317192_ChIP-Seq_ERMYB_Mouse1.75427633
31* HOXB4_20404135_ChIP-ChIP_EML_Mouse1.71627810
32SPI1_22096565_ChIP-ChIP_GC-B_Mouse1.71238511
33ERG_20887958_ChIP-Seq_HPC-7_Mouse1.66978707
34* SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse1.65289164
35ASXL1_24218140_ChIP-Seq_BMDM_Mouse1.65032464
36* FLI1_20887958_ChIP-Seq_HPC-7_Mouse1.63354819
37LMO2_20887958_ChIP-Seq_HPC-7_Mouse1.60860632
38* RUNX1_22412390_ChIP-Seq_EML_Mouse1.60437522
39* GATA2_19941826_ChIP-Seq_K562_Human1.59676731
40* GATA2_21666600_ChIP-Seq_HMVEC_Human1.58840095
41XRN2_22483619_ChIP-Seq_HELA_Human1.58676726
42* TCF7_22412390_ChIP-Seq_EML_Mouse1.58591712
43EST1_17652178_ChIP-ChIP_JURKAT_Human1.58505763
44FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse1.58468420
45VDR_23849224_ChIP-Seq_CD4+_Human1.55021529
46GATA2_22383799_ChIP-Seq_G1ME_Mouse1.54844564
47LYL1_20887958_ChIP-Seq_HPC-7_Mouse1.54181301
48MAF_26560356_Chip-Seq_TH1_Human1.52561507
49CIITA_25753668_ChIP-Seq_RAJI_Human1.50552891
50MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.49831464
51HCFC1_20581084_ChIP-Seq_MESCs_Mouse1.48035376
52VDR_24763502_ChIP-Seq_THP-1_Human1.45203480
53NELFA_20434984_ChIP-Seq_ESCs_Mouse1.44136330
54SFPI1_20887958_ChIP-Seq_HPC-7_Mouse1.43859947
55ETS1_20019798_ChIP-Seq_JURKAT_Human1.42011493
56FOXP3_21729870_ChIP-Seq_TREG_Human1.41153974
57UTX_26944678_Chip-Seq_JUKART_Human1.41013491
58IRF8_22096565_ChIP-ChIP_GC-B_Human1.40433300
59SPI1_23547873_ChIP-Seq_NB4_Human1.40005023
60* IRF8_27001747_Chip-Seq_BMDM_Mouse1.37367508
61TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse1.34747758
62IRF8_22096565_ChIP-ChIP_GC-B_Mouse1.32306677
63AR_21909140_ChIP-Seq_LNCAP_Human1.32001807
64Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse1.31700735
65HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse1.31460062
66NOTCH1_21737748_ChIP-Seq_TLL_Human1.31017107
67* BRD4_27068464_Chip-Seq_AML-cells_Mouse1.30390644
68FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse1.29278804
69MYBL2_22936984_ChIP-ChIP_MESCs_Mouse1.28756897
70ESR1_15608294_ChIP-ChIP_MCF-7_Human1.27536839
71KDM2B_26808549_Chip-Seq_SIL-ALL_Human1.26528853
72THAP11_20581084_ChIP-Seq_MESCs_Mouse1.26213270
73CREB1_15753290_ChIP-ChIP_HEK293T_Human1.24898100
74* ETS1_22383799_ChIP-Seq_G1ME_Mouse1.23272462
75RUNX_20019798_ChIP-Seq_JUKART_Human1.23122098
76GATA2_20887958_ChIP-Seq_HPC-7_Mouse1.22772120
77ZNF263_19887448_ChIP-Seq_K562_Human1.21458177
78STAT6_20620947_ChIP-Seq_CD4_POS_T_Human1.20529370
79STAT4_19710469_ChIP-ChIP_TH1__Mouse1.19664685
80* NCOR1_26117541_ChIP-Seq_K562_Human1.18959151
81TTF2_22483619_ChIP-Seq_HELA_Human1.18317640
82MEIS1_20887958_ChIP-Seq_HPC-7_Mouse1.17515690
83PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse1.14987134
84MYB_26560356_Chip-Seq_TH2_Human1.13974556
85FOXP2_23625967_ChIP-Seq_PFSK-1_AND_SK-N-MC_Human1.11326714
86MYB_26560356_Chip-Seq_TH1_Human1.11019071
87GATA3_27048872_Chip-Seq_THYMUS_Human1.10884776
88GATA2_21571218_ChIP-Seq_MEGAKARYOCYTES_Human1.09761180
89E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human1.09757406
90E2F1_18555785_ChIP-Seq_MESCs_Mouse1.09735120
91GFI1B_20887958_ChIP-Seq_HPC-7_Mouse1.09681941
92CCND1_20090754_ChIP-ChIP_RETINA_Mouse1.09414985
93ELK1_19687146_ChIP-ChIP_HELA_Human1.09359400
94DCP1A_22483619_ChIP-Seq_HELA_Human1.09226258
95GATA1_19941827_ChIP-Seq_MEL86_Mouse1.08828004
96NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse1.08692572
97* ELK3_25401928_ChIP-Seq_HUVEC_Human1.08633859
98NOTCH1_17114293_ChIP-ChIP_T-ALL_Human1.07392701
99KDM5A_27292631_Chip-Seq_BREAST_Human1.06036986
100KDM2B_26808549_Chip-Seq_HPB-ALL_Human1.05979232
101GABP_17652178_ChIP-ChIP_JURKAT_Human1.05950816
102TFEB_21752829_ChIP-Seq_HELA_Human1.05869676
103IRF8_21731497_ChIP-ChIP_J774_Mouse1.05433575
104* ZFX_18555785_ChIP-Seq_MESCs_Mouse1.04284087
105SPI1_20517297_ChIP-Seq_HL60_Human1.03168008
106FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse1.02334852
107KDM2B_26808549_Chip-Seq_DND41_Human1.02159116
108GABP_19822575_ChIP-Seq_HepG2_Human1.01989281
109NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human1.01651958
110E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human1.00979986
111MYCN_18555785_ChIP-Seq_MESCs_Mouse1.00742102
112STAT3_20064451_ChIP-Seq_CD4+T_Mouse0.99646408
113* SALL4_22934838_ChIP-ChIP_CD34+_Human0.99355538
114* RUNX1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.98907624
115* NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse0.98901926
116SRF_21415370_ChIP-Seq_HL-1_Mouse0.98842270
117CUX1_19635798_ChIP-ChIP_MULTIPLE_HUMAN_CANCER_TYPES_Human0.97865610
118IRF1_21803131_ChIP-Seq_MONOCYTES_Human0.97113938
119MAF_26560356_Chip-Seq_TH2_Human0.96347961
120CHD1_19587682_ChIP-ChIP_MESCs_Mouse0.95998449
121PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse0.95375932
122GATA1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.94621707
123* CTCF_27219007_Chip-Seq_ERYTHROID_Human0.86021651
124* FLI1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.80893231
125* ELF1_20517297_ChIP-Seq_JURKAT_Human0.80717301
126CTCF_21964334_ChIP-Seq_BJAB-B_Human0.80590404
127WT1_19549856_ChIP-ChIP_CCG9911_Human0.79773755
128PU_27001747_Chip-Seq_BMDM_Mouse0.79264275
129PRDM5_23873026_ChIP-Seq_MEFs_Mouse0.75290837
130FOXP3_17237761_ChIP-ChIP_TREG_Mouse0.73814844
131GATA3_26560356_Chip-Seq_TH2_Human0.73570862
132RUNX1_17652178_ChIP-ChIP_JURKAT_Human0.73436432
133GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.66847353
134VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human0.66471487
135NFE2L2_22581777_ChIP-Seq_LYMPHOBLASTOID_Human0.65842273
136* BCL3_23251550_ChIP-Seq_MUSCLE_Mouse0.65809305
137BCOR_27268052_Chip-Seq_Bcells_Human0.64066933
138SALL4_18804426_ChIP-ChIP_XEN_Mouse0.63970474

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0004147_increased_porphyrin_level7.82557143
2MP0003656_abnormal_erythrocyte_physiolo7.41758553
3MP0001545_abnormal_hematopoietic_system3.43711655
4MP0005397_hematopoietic_system_phenotyp3.43711655
5MP0002396_abnormal_hematopoietic_system3.34788369
6MP0004808_abnormal_hematopoietic_stem3.13250881
7MP0003111_abnormal_nucleus_morphology2.93116816
8MP0010094_abnormal_chromosome_stability2.73247815
9MP0005464_abnormal_platelet_physiology2.56638818
10MP0005083_abnormal_biliary_tract2.43917534
11MP0000465_gastrointestinal_hemorrhage2.31256844
12MP0009278_abnormal_bone_marrow2.30462696
13MP0003077_abnormal_cell_cycle2.20351975
14MP0002877_abnormal_melanocyte_morpholog2.12917834
15* MP0002398_abnormal_bone_marrow2.09277422
16MP0006054_spinal_hemorrhage2.08099328
17MP0000490_abnormal_crypts_of1.98318982
18MP0003693_abnormal_embryo_hatching1.95504242
19MP0008004_abnormal_stomach_pH1.90368218
20MP0009697_abnormal_copulation1.89297413
21MP0005174_abnormal_tail_pigmentation1.88827579
22* MP0002722_abnormal_immune_system1.82287546
23* MP0000689_abnormal_spleen_morphology1.76399565
24MP0010307_abnormal_tumor_latency1.66686773
25* MP0002429_abnormal_blood_cell1.58996641
26MP0008057_abnormal_DNA_replication1.58940589
27MP0008058_abnormal_DNA_repair1.57105838
28MP0000685_abnormal_immune_system1.54905580
29MP0004957_abnormal_blastocyst_morpholog1.54001835
30MP0003943_abnormal_hepatobiliary_system1.52807875
31MP0005671_abnormal_response_to1.52550024
32MP0003567_abnormal_fetal_cardiomyocyte1.51746249
33MP0009333_abnormal_splenocyte_physiolog1.42647798
34MP0002095_abnormal_skin_pigmentation1.39944498
35MP0003172_abnormal_lysosome_physiology1.39702251
36MP0000703_abnormal_thymus_morphology1.36546103
37MP0008007_abnormal_cellular_replicative1.35188337
38MP0000716_abnormal_immune_system1.27866033
39MP0010368_abnormal_lymphatic_system1.23426064
40MP0005025_abnormal_response_to1.22173142
41* MP0000313_abnormal_cell_death1.21006022
42MP0005075_abnormal_melanosome_morpholog1.19026214
43MP0002132_abnormal_respiratory_system1.18457001
44MP0002019_abnormal_tumor_incidence1.18402303
45MP0003300_gastrointestinal_ulcer1.16184553
46MP0002420_abnormal_adaptive_immunity1.15017220
47MP0001819_abnormal_immune_cell1.13773288
48MP0000350_abnormal_cell_proliferation1.12190535
49MP0005636_abnormal_mineral_homeostasis1.11771281
50MP0001835_abnormal_antigen_presentation1.10609286
51MP0004084_abnormal_cardiac_muscle1.09157821
52MP0002452_abnormal_antigen_presenting1.04405413
53MP0002405_respiratory_system_inflammati1.03847548
54MP0001800_abnormal_humoral_immune1.03297847
55MP0009379_abnormal_foot_pigmentation1.01870325
56MP0008260_abnormal_autophagy1.01228092
57MP0004130_abnormal_muscle_cell0.99500973
58MP0001879_abnormal_lymphatic_vessel0.98635409
59MP0005084_abnormal_gallbladder_morpholo0.97218331
60MP0001853_heart_inflammation0.96999465
61MP0003436_decreased_susceptibility_to0.96764482
62* MP0002086_abnormal_extraembryonic_tissu0.96064522
63MP0002723_abnormal_immune_serum0.94819890
64MP0003724_increased_susceptibility_to0.94184711
65MP0010030_abnormal_orbit_morphology0.91835612
66MP0002419_abnormal_innate_immunity0.91504464
67MP0000598_abnormal_liver_morphology0.90562306
68* MP0008770_decreased_survivor_rate0.88080894
69MP0008775_abnormal_heart_ventricle0.87894263
70* MP0002080_prenatal_lethality0.87060772
71MP0001915_intracranial_hemorrhage0.86653701
72MP0010155_abnormal_intestine_physiology0.86074236
73MP0005000_abnormal_immune_tolerance0.85851714
74MP0006036_abnormal_mitochondrial_physio0.84030273
75MP0003303_peritoneal_inflammation0.83985377
76MP0003191_abnormal_cellular_cholesterol0.83850936
77MP0003866_abnormal_defecation0.82641163
78MP0001873_stomach_inflammation0.82587935
79MP0002148_abnormal_hypersensitivity_rea0.81910940
80MP0003186_abnormal_redox_activity0.81744700
81MP0002166_altered_tumor_susceptibility0.81394247
82MP0005451_abnormal_body_composition0.79315017
83MP0009785_altered_susceptibility_to0.79096646
84* MP0001697_abnormal_embryo_size0.78722729
85* MP0009931_abnormal_skin_appearance0.78242034
86* MP0001730_embryonic_growth_arrest0.77064215
87MP0000609_abnormal_liver_physiology0.76735741
88MP0001851_eye_inflammation0.75791772
89MP0003763_abnormal_thymus_physiology0.75130213
90MP0004036_abnormal_muscle_relaxation0.74943402
91MP0010352_gastrointestinal_tract_polyps0.73847932
92MP0004947_skin_inflammation0.73827839
93MP0000372_irregular_coat_pigmentation0.73801321
94MP0004197_abnormal_fetal_growth/weight/0.72463437
95MP0009765_abnormal_xenobiotic_induced0.72273417
96MP0002009_preneoplasia0.71501229
97MP0000343_altered_response_to0.71443588
98MP0005387_immune_system_phenotype0.71185138
99MP0001790_abnormal_immune_system0.71185138
100* MP0003984_embryonic_growth_retardation0.70306400
101MP0003828_pulmonary_edema0.70153783
102MP0002928_abnormal_bile_duct0.69504081
103MP0005167_abnormal_blood-brain_barrier0.69086669
104MP0001663_abnormal_digestive_system0.68328833
105MP0000230_abnormal_systemic_arterial0.68120705
106MP0009763_increased_sensitivity_to0.67890150
107* MP0002088_abnormal_embryonic_growth/wei0.67718716
108MP0000858_altered_metastatic_potential0.66674708
109MP0002138_abnormal_hepatobiliary_system0.65712694
110MP0000015_abnormal_ear_pigmentation0.64901135
111* MP0005380_embryogenesis_phenotype0.64355638
112* MP0001672_abnormal_embryogenesis/_devel0.64355638
113MP0006035_abnormal_mitochondrial_morpho0.63348288
114MP0003045_fibrosis0.63004774
115MP0000249_abnormal_blood_vessel0.62499431
116MP0008872_abnormal_physiological_respon0.62474194
117MP0003786_premature_aging0.62473674
118MP0005171_absent_coat_pigmentation0.62003442
119MP0009764_decreased_sensitivity_to0.61789078
120MP0006276_abnormal_autonomic_nervous0.61243667
121MP0008995_early_reproductive_senescence0.61238298
122MP0000477_abnormal_intestine_morphology0.61226112
123MP0005058_abnormal_lysosome_morphology0.61218639
124MP0008469_abnormal_protein_level0.60834876
125MP0001845_abnormal_inflammatory_respons0.60332269
126MP0003718_maternal_effect0.59047655
127MP0003566_abnormal_cell_adhesion0.58002015
128MP0005535_abnormal_body_temperature0.57786942
129MP0005647_abnormal_sex_gland0.56269865
130MP0004484_altered_response_of0.55478779

Predicted human phenotypes

RankGene SetZ-score
1Poikilocytosis (HP:0004447)9.72096628
2Acanthocytosis (HP:0001927)7.04286934
3Abnormality of cells of the erythroid lineage (HP:0012130)6.29470581
4Abnormal number of erythroid precursors (HP:0012131)6.23361382
5Petechiae (HP:0000967)6.07676668
6Reticulocytosis (HP:0001923)6.03113319
7Hypochromic microcytic anemia (HP:0004840)5.72670237
8Prolonged bleeding time (HP:0003010)5.54449401
9Abnormal hemoglobin (HP:0011902)5.37241302
10Abnormality of reticulocytes (HP:0004312)5.25086449
11Impaired platelet aggregation (HP:0003540)4.18925444
12Abnormal platelet function (HP:0011869)4.18925444
13Hypochromic anemia (HP:0001931)3.94571417
14Cholelithiasis (HP:0001081)3.91579533
15Reticulocytopenia (HP:0001896)3.86372014
16Microcytic anemia (HP:0001935)3.85386274
17Hyperbilirubinemia (HP:0002904)3.82721502
18Pallor (HP:0000980)3.81386390
19Diaphragmatic weakness (HP:0009113)3.78335954
20Aplastic anemia (HP:0001915)3.66531759
21Insomnia (HP:0100785)3.63478999
22Paralysis (HP:0003470)3.59114944
23Epistaxis (HP:0000421)3.58945755
24Polycythemia (HP:0001901)3.49988336
25Thrombocytosis (HP:0001894)3.47357497
26Macrocytic anemia (HP:0001972)3.46832488
27Abnormal gallbladder morphology (HP:0012437)3.35168008
28Purpura (HP:0000979)3.32724352
29Cutaneous photosensitivity (HP:0000992)3.17985871
30Osteomalacia (HP:0002749)3.02356381
31Abnormal platelet volume (HP:0011876)3.01471853
32Asplenia (HP:0001746)2.90248934
33Aplasia/Hypoplasia of the middle phalanx of the 5th finger (HP:0009161)2.85601877
34Birth length less than 3rd percentile (HP:0003561)2.81172408
35Increased mean platelet volume (HP:0011877)2.75500147
36Menorrhagia (HP:0000132)2.74310702
37Hypertensive crisis (HP:0100735)2.63265551
38Increased serum ferritin (HP:0003281)2.61075388
39Myelodysplasia (HP:0002863)2.59118946
40Aplasia/Hypoplasia of the spleen (HP:0010451)2.54445265
41Aplasia/Hypoplasia of the phalanges of the 5th finger (HP:0009376)2.54026523
42Hyperthyroidism (HP:0000836)2.47452628
43IgM deficiency (HP:0002850)2.38475973
44Gingival bleeding (HP:0000225)2.37084480
45Abnormality of the gallbladder (HP:0005264)2.31562011
46Chronic otitis media (HP:0000389)2.31143628
47Short middle phalanx of the 5th finger (HP:0004220)2.30895474
48Abnormality of the middle phalanx of the 5th finger (HP:0004219)2.30204578
49Abnormality of iron homeostasis (HP:0011031)2.28133041
50Autoimmune hemolytic anemia (HP:0001890)2.23867908
51Truncus arteriosus (HP:0001660)2.21050868
52Abnormal gallbladder physiology (HP:0012438)2.20433049
53Cholecystitis (HP:0001082)2.20433049
54Obstructive lung disease (HP:0006536)2.13370788
55Chronic obstructive pulmonary disease (HP:0006510)2.13370788
56Nausea (HP:0002018)2.12342616
57Depressed nasal tip (HP:0000437)2.11177069
58Cellulitis (HP:0100658)2.07494828
59Abnormality of the phalanges of the 5th finger (HP:0004213)2.07096940
60Acute myeloid leukemia (HP:0004808)2.03290501
61Abnormality of the heme biosynthetic pathway (HP:0010472)11.6019749
62Abnormality of the fingertips (HP:0001211)1.99941166
63Urticaria (HP:0001025)1.99895109
64Annular pancreas (HP:0001734)1.98501858
65Cerebral palsy (HP:0100021)1.97380852
66Osteomyelitis (HP:0002754)1.95821570
67Conjunctival telangiectasia (HP:0000524)1.94276496
68Hyperlipoproteinemia (HP:0010980)1.93763442
69Acute lymphatic leukemia (HP:0006721)1.93402436
70Toxemia of pregnancy (HP:0100603)1.92816162
71Spontaneous hematomas (HP:0007420)1.91950255
72Abnormality of transition element cation homeostasis (HP:0011030)1.91921819
73Broad palm (HP:0001169)1.90632527
74Prominent nose (HP:0000448)1.90230936
75Intestinal atresia (HP:0011100)1.89779279
76Anterior segment dysgenesis (HP:0007700)1.89632582
77Orthostatic hypotension (HP:0001278)1.89347004
78Albinism (HP:0001022)1.88205641
79Gastrointestinal infarctions (HP:0005244)1.87456819
80Thrombophlebitis (HP:0004418)1.85845983
81High pitched voice (HP:0001620)1.85444171
82Ventricular fibrillation (HP:0001663)1.84573671
83Amaurosis fugax (HP:0100576)1.83238345
84Abnormal large intestine physiology (HP:0012700)1.81840765
85Tinnitus (HP:0000360)1.80512600
86Seborrheic dermatitis (HP:0001051)1.79895668
87Recurrent viral infections (HP:0004429)1.79269292
88Abnormality of the vasculature of the conjunctiva (HP:0008054)1.78568785
89Pustule (HP:0200039)1.78101442
90Hypoparathyroidism (HP:0000829)1.77858007
91Encephalitis (HP:0002383)1.77389748
92Dyschromatopsia (HP:0007641)1.77006714
93Bowel incontinence (HP:0002607)1.76146408
94Thyroid carcinoma (HP:0002890)1.74654523
95Papillary thyroid carcinoma (HP:0002895)1.73827468
96Basal cell carcinoma (HP:0002671)1.73784298
97Migraine (HP:0002076)1.73721875
98Parkinsonism with favorable response to dopaminergic medication (HP:0002548)1.73429005
99Recurrent bacterial skin infections (HP:0005406)1.72573834
100Autoimmune thrombocytopenia (HP:0001973)1.71878523
101Volvulus (HP:0002580)1.70116878
102Abnormal delayed hypersensitivity skin test (HP:0002963)1.68360290
103Inflammation of the large intestine (HP:0002037)1.67182935
104Hyponatremia (HP:0002902)1.66846233
105Bruising susceptibility (HP:0000978)1.66169249
106Abnormality of macrophages (HP:0004311)1.64910935
107Gastrointestinal dysmotility (HP:0002579)1.63970391
108Abnormality of homocysteine metabolism (HP:0010919)1.63956327
109Homocystinuria (HP:0002156)1.63956327
110Supernumerary spleens (HP:0009799)1.63794694
111Arterial thrombosis (HP:0004420)1.63640377
112Abnormality of the nasal mucosa (HP:0000433)1.60616507
113Hepatosplenomegaly (HP:0001433)1.60398536
114Abnormality of the prostate (HP:0008775)1.58395938
115Recurrent fungal infections (HP:0002841)1.57921631
116Increased neuronal autofluorescent lipopigment (HP:0002074)1.56387780
117Hematochezia (HP:0002573)1.56233379
118Nonimmune hydrops fetalis (HP:0001790)1.55856243
119Recurrent abscess formation (HP:0002722)1.55713403
120Granulocytopenia (HP:0001913)1.55339110
121Poikiloderma (HP:0001029)1.54766136
122Aplasia/Hypoplasia of the earlobes (HP:0009906)1.54361373
123Fatigue (HP:0012378)1.53951152
124Cerebral hemorrhage (HP:0001342)1.51374028
125Leukocytosis (HP:0001974)1.50919189
126Abnormality of the duodenum (HP:0002246)1.50478134
127Abnormality of T cell physiology (HP:0011840)1.50341711
128Splenomegaly (HP:0001744)1.50116576
129Hyperacusis (HP:0010780)1.49946014
130Stomatitis (HP:0010280)1.48772624
131Hepatocellular carcinoma (HP:0001402)1.47514736
132Abnormality of the thoracic spine (HP:0100711)1.45954128
133Eczematoid dermatitis (HP:0000976)1.45786617
134Chromsome breakage (HP:0040012)1.44742498
135Erythema (HP:0010783)1.43984309
136Gastrointestinal inflammation (HP:0004386)1.43241040
137Panhypogammaglobulinemia (HP:0003139)1.42477029
138Ileus (HP:0002595)1.39438007
139Cutaneous melanoma (HP:0012056)1.39133952
140Squamous cell carcinoma (HP:0002860)1.38535572
141Duodenal stenosis (HP:0100867)1.38224265
142Small intestinal stenosis (HP:0012848)1.38224265
143Exertional dyspnea (HP:0002875)1.36466303
144Megalocornea (HP:0000485)1.36302907
145Bone marrow hypocellularity (HP:0005528)1.36023612
146Abnormality of chromosome stability (HP:0003220)1.35563725
147Increased nuchal translucency (HP:0010880)1.35550735

Predicted kinase interactions (KEA)

RankGene SetZ-score
1RIPK44.58077232
2EEF2K4.18877034
3EIF2AK13.87883673
4CDC73.17432444
5TIE13.06400063
6NME22.65492581
7BMX2.63536638
8TGFBR22.11865619
9TLK12.07726395
10MAP2K32.03157769
11PRPF4B2.00790075
12KIT1.97771988
13STK41.96003737
14KDR1.88028866
15VRK11.87877298
16TGFBR11.80341949
17WEE11.80174275
18RPS6KB21.78002306
19MAP4K11.76361299
20SCYL21.75080153
21MAP3K101.68363280
22BMPR21.61348544
23PIM11.61343487
24DYRK31.61091661
25PTK2B1.59368166
26TAOK21.51801672
27MAPKAPK51.47169663
28PKN21.47051991
29MST41.42347042
30TAOK31.40485126
31PIM21.40148209
32NEK21.38166223
33MKNK11.35487113
34CDK61.35396864
35CDK121.34848382
36BTK1.32181511
37SYK1.30751360
38STK101.27540617
39PIK3CG1.27119303
40MATK1.22469465
41CDK41.19134039
42PLK41.18733341
43HCK1.17341360
44ZAK1.11454791
45LRRK21.10695909
46BUB11.10556355
47MAPKAPK31.10505062
48RAF11.08905713
49STK31.08825418
50KSR21.07991423
51ATR1.06674294
52TEC1.05360104
53MARK31.05328853
54BRSK11.04227927
55AURKB1.03833626
56MUSK1.02734662
57ZAP701.02512528
58STK161.00389995
59RPS6KA50.98895685
60MAP3K10.98109130
61WNK10.97623583
62BRSK20.96648517
63JAK30.95939506
64NUAK10.95582678
65TNK20.95327362
66MAP3K80.95152054
67TAOK10.94662639
68MAP3K60.94597662
69BLK0.93873669
70IKBKB0.92690340
71ITK0.91553903
72TRPM70.89965794
73INSRR0.89637072
74MAP3K110.89600091
75BRD40.86964312
76CDK190.86533412
77CDK70.85739111
78FLT30.84613324
79GRK60.83492847
80MAPK110.82917883
81MAP3K20.82436566
82LYN0.82250886
83CDK80.81856319
84TBK10.80467582
85CDK90.78968004
86TYK20.77023040
87TRIB30.76745134
88MAP3K50.75894172
89JAK20.75632008
90AKT20.74712548
91MKNK20.70968560
92PASK0.70153701
93KSR10.69064803
94MAP3K30.68677749
95SIK20.67513501
96FGR0.66930646
97PRKAA20.65286643
98TXK0.63345200
99CAMK1G0.62399604
100GRK50.61827869
101IRAK10.61745989
102IKBKE0.61656776
103YES10.61435994
104SGK20.61176805
105SRPK10.60514650
106PAK40.60498055
107CSF1R0.60484179
108RPS6KA60.58836017
109PLK10.58470311
110CHEK10.58256968
111MAP2K20.58217101
112CHEK20.57957569
113ATM0.56596096
114PINK10.54663636
115RPS6KL10.54405558
116RPS6KC10.54405558
117SGK30.54005435
118TSSK60.53979821
119CLK10.53498508
120RPS6KA20.53153865
121HIPK20.52547123
122CAMK1D0.52500964
123MAPKAPK20.51661762
124ALK0.50947948
125RET0.50405009
126AURKA0.50135727
127PRKCQ0.49967231
128DYRK1B0.49930407
129PLK30.49533384
130CDK20.49006254
131CCNB10.48955624
132CSK0.47989161
133FES0.45342200
134MAPK120.45106344
135RPS6KA40.44467752
136TTK0.44134662
137ACVR1B0.43911112
138LCK0.43897450
139PDK10.42165207
140MAPK40.40604798
141PLK20.39984689
142IRAK40.36928396
143PDPK10.36139824
144SGK10.34907863
145* PRKACG0.30750235
146MAP3K70.30358277
147NTRK30.29922983
148IRAK30.28871109
149PAK10.26731886

Predicted pathways (KEGG)

RankGene SetZ-score
1Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008605.06393145
2DNA replication_Homo sapiens_hsa030304.51924076
3Ribosome_Homo sapiens_hsa030104.42782176
4Butirosin and neomycin biosynthesis_Homo sapiens_hsa005243.95790123
5Systemic lupus erythematosus_Homo sapiens_hsa053223.42943155
6Mismatch repair_Homo sapiens_hsa034302.90100879
7Base excision repair_Homo sapiens_hsa034102.49088418
8Cell cycle_Homo sapiens_hsa041102.42848147
9Spliceosome_Homo sapiens_hsa030402.36411255
10Homologous recombination_Homo sapiens_hsa034402.08145244
11Nucleotide excision repair_Homo sapiens_hsa034202.03321053
12Nitrogen metabolism_Homo sapiens_hsa009101.96940602
13One carbon pool by folate_Homo sapiens_hsa006701.95171531
14Hematopoietic cell lineage_Homo sapiens_hsa046401.91305350
15Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007601.90052452
16Vitamin B6 metabolism_Homo sapiens_hsa007501.88184843
17Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005331.82619647
18Alcoholism_Homo sapiens_hsa050341.73820722
19Pyrimidine metabolism_Homo sapiens_hsa002401.70864882
20RNA transport_Homo sapiens_hsa030131.69300960
21Fanconi anemia pathway_Homo sapiens_hsa034601.64495001
22Transcriptional misregulation in cancer_Homo sapiens_hsa052021.56520928
23p53 signaling pathway_Homo sapiens_hsa041151.54302954
24Viral carcinogenesis_Homo sapiens_hsa052031.52813741
25African trypanosomiasis_Homo sapiens_hsa051431.50915426
26Chronic myeloid leukemia_Homo sapiens_hsa052201.50078157
27Herpes simplex infection_Homo sapiens_hsa051681.45125075
28RNA degradation_Homo sapiens_hsa030181.39705165
29Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006041.36013161
30Platelet activation_Homo sapiens_hsa046111.31803056
31RNA polymerase_Homo sapiens_hsa030201.30102572
32Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030081.29292937
33Leishmaniasis_Homo sapiens_hsa051401.20538078
34Non-homologous end-joining_Homo sapiens_hsa034501.19370200
35Sulfur relay system_Homo sapiens_hsa041221.19010290
36Apoptosis_Homo sapiens_hsa042101.18948194
37Glycerophospholipid metabolism_Homo sapiens_hsa005641.18692366
38B cell receptor signaling pathway_Homo sapiens_hsa046621.16227063
39Renal cell carcinoma_Homo sapiens_hsa052111.15160591
40Measles_Homo sapiens_hsa051621.14223946
41Olfactory transduction_Homo sapiens_hsa047401.10999133
42Hepatitis B_Homo sapiens_hsa051611.10719202
43Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006031.08710581
44mRNA surveillance pathway_Homo sapiens_hsa030151.06752885
45Acute myeloid leukemia_Homo sapiens_hsa052211.04534984
46Cytosolic DNA-sensing pathway_Homo sapiens_hsa046231.03798260
47Small cell lung cancer_Homo sapiens_hsa052221.03659533
48Non-small cell lung cancer_Homo sapiens_hsa052231.03372287
49Regulation of lipolysis in adipocytes_Homo sapiens_hsa049231.01510234
50Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009701.00655626
51Adipocytokine signaling pathway_Homo sapiens_hsa049200.98301194
52Collecting duct acid secretion_Homo sapiens_hsa049660.97844142
53Malaria_Homo sapiens_hsa051440.97435073
54Regulation of autophagy_Homo sapiens_hsa041400.97348317
55ABC transporters_Homo sapiens_hsa020100.97041926
56Type II diabetes mellitus_Homo sapiens_hsa049300.96605078
57Fc epsilon RI signaling pathway_Homo sapiens_hsa046640.95983864
58Carbohydrate digestion and absorption_Homo sapiens_hsa049730.92776881
59VEGF signaling pathway_Homo sapiens_hsa043700.90512483
60Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.90196232
61mTOR signaling pathway_Homo sapiens_hsa041500.88473033
62Inositol phosphate metabolism_Homo sapiens_hsa005620.87625720
63Tuberculosis_Homo sapiens_hsa051520.86939405
64RIG-I-like receptor signaling pathway_Homo sapiens_hsa046220.86024410
65T cell receptor signaling pathway_Homo sapiens_hsa046600.81195755
66Selenocompound metabolism_Homo sapiens_hsa004500.81139704
67Phosphatidylinositol signaling system_Homo sapiens_hsa040700.80681015
68Antigen processing and presentation_Homo sapiens_hsa046120.80074524
69Osteoclast differentiation_Homo sapiens_hsa043800.79975741
70Asthma_Homo sapiens_hsa053100.79585882
71Pancreatic cancer_Homo sapiens_hsa052120.78867366
72Purine metabolism_Homo sapiens_hsa002300.78822407
73Epstein-Barr virus infection_Homo sapiens_hsa051690.77607804
74Jak-STAT signaling pathway_Homo sapiens_hsa046300.76241645
75Proteasome_Homo sapiens_hsa030500.75946462
76Choline metabolism in cancer_Homo sapiens_hsa052310.75031847
77Notch signaling pathway_Homo sapiens_hsa043300.71852548
78Glioma_Homo sapiens_hsa052140.71312210
79HTLV-I infection_Homo sapiens_hsa051660.69277957
80Staphylococcus aureus infection_Homo sapiens_hsa051500.68852823
81NF-kappa B signaling pathway_Homo sapiens_hsa040640.66523883
82Dorso-ventral axis formation_Homo sapiens_hsa043200.66459483
83Long-term depression_Homo sapiens_hsa047300.65505910
84Phospholipase D signaling pathway_Homo sapiens_hsa040720.64573437
85Influenza A_Homo sapiens_hsa051640.64375334
86Toll-like receptor signaling pathway_Homo sapiens_hsa046200.62939680
87Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.62267935
88Toxoplasmosis_Homo sapiens_hsa051450.62047950
89Vascular smooth muscle contraction_Homo sapiens_hsa042700.61018669
90Arachidonic acid metabolism_Homo sapiens_hsa005900.60993030
91Basal transcription factors_Homo sapiens_hsa030220.60194932
92Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046660.59614253
93Bladder cancer_Homo sapiens_hsa052190.58487527
94Legionellosis_Homo sapiens_hsa051340.56259552
95Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047500.52442785
96Longevity regulating pathway - mammal_Homo sapiens_hsa042110.51956493
97Renin-angiotensin system_Homo sapiens_hsa046140.51248130
98Shigellosis_Homo sapiens_hsa051310.50202727
99Endometrial cancer_Homo sapiens_hsa052130.48714550
100Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.48595845
101N-Glycan biosynthesis_Homo sapiens_hsa005100.48091127
102AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049330.46736409
103MicroRNAs in cancer_Homo sapiens_hsa052060.46362470
104Thyroid cancer_Homo sapiens_hsa052160.44976264
105Glycerolipid metabolism_Homo sapiens_hsa005610.44673507
106Sphingolipid signaling pathway_Homo sapiens_hsa040710.43990872
107Leukocyte transendothelial migration_Homo sapiens_hsa046700.43669260
108Primary immunodeficiency_Homo sapiens_hsa053400.42456275
109Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.42191037
110FoxO signaling pathway_Homo sapiens_hsa040680.41747629
111Gap junction_Homo sapiens_hsa045400.40790219
112Intestinal immune network for IgA production_Homo sapiens_hsa046720.39605539
113Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046500.38952051
114Prostate cancer_Homo sapiens_hsa052150.38949558
115Cysteine and methionine metabolism_Homo sapiens_hsa002700.38695878
116Insulin signaling pathway_Homo sapiens_hsa049100.38366549
117Pentose phosphate pathway_Homo sapiens_hsa000300.38298517
118Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.37731216
119Endocytosis_Homo sapiens_hsa041440.37381932
120Prolactin signaling pathway_Homo sapiens_hsa049170.37020850
121Colorectal cancer_Homo sapiens_hsa052100.36556986
122Melanoma_Homo sapiens_hsa052180.36059148
123Pertussis_Homo sapiens_hsa051330.35834343
124HIF-1 signaling pathway_Homo sapiens_hsa040660.34966851
125Chagas disease (American trypanosomiasis)_Homo sapiens_hsa051420.34662926
126Rap1 signaling pathway_Homo sapiens_hsa040150.34258167
127Lysine degradation_Homo sapiens_hsa003100.34003710
128Oocyte meiosis_Homo sapiens_hsa041140.33980973
129Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.33829520
130Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.33760263
131TNF signaling pathway_Homo sapiens_hsa046680.33401271
132Caffeine metabolism_Homo sapiens_hsa002320.33353748
133Hepatitis C_Homo sapiens_hsa051600.32877764
134NOD-like receptor signaling pathway_Homo sapiens_hsa046210.32708699
135Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.32064930
136Phagosome_Homo sapiens_hsa041450.31977309
137Neurotrophin signaling pathway_Homo sapiens_hsa047220.27270471
138SNARE interactions in vesicular transport_Homo sapiens_hsa041300.26353287
139Folate biosynthesis_Homo sapiens_hsa007900.26049582
140Chemokine signaling pathway_Homo sapiens_hsa040620.25899050
141Cyanoamino acid metabolism_Homo sapiens_hsa004600.25678717
142AMPK signaling pathway_Homo sapiens_hsa041520.21389683

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