TAF9BP1

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1positive regulation of action potential (GO:0045760)8.28990265
2aggressive behavior (GO:0002118)7.59792381
3positive regulation of vascular permeability (GO:0043117)7.05753339
4positive regulation of uterine smooth muscle contraction (GO:0070474)6.98957736
5urinary tract smooth muscle contraction (GO:0014848)6.84480528
6drinking behavior (GO:0042756)5.57349063
7regulation of uterine smooth muscle contraction (GO:0070472)5.37696563
8regulation of action potential (GO:0098900)5.35958972
9positive regulation of digestive system process (GO:0060456)5.16281169
10RNA destabilization (GO:0050779)5.11442260
11behavioral response to ethanol (GO:0048149)5.00437256
12behavioral response to pain (GO:0048266)4.70957868
13epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287)4.70674951
14cilium or flagellum-dependent cell motility (GO:0001539)4.60270256
15diterpenoid biosynthetic process (GO:0016102)4.56672174
16negative regulation of synaptic transmission, glutamatergic (GO:0051967)4.03605818
17terpenoid biosynthetic process (GO:0016114)3.95603810
18positive regulation of synaptic transmission, GABAergic (GO:0032230)3.85422603
19fusion of sperm to egg plasma membrane (GO:0007342)3.66272763
20neural tube formation (GO:0001841)3.47853485
21S-adenosylmethionine metabolic process (GO:0046500)3.41264191
22retinal cone cell development (GO:0046549)3.40972133
23regulation of cilium movement (GO:0003352)3.40257790
24positive regulation of oligodendrocyte differentiation (GO:0048714)3.35602988
25establishment of protein localization to Golgi (GO:0072600)3.35139458
26response to auditory stimulus (GO:0010996)3.28521627
27axoneme assembly (GO:0035082)3.26971358
28pyrimidine nucleobase catabolic process (GO:0006208)3.26633241
29retinal metabolic process (GO:0042574)3.24796771
30negative regulation of digestive system process (GO:0060457)3.21620693
31cellular ketone body metabolic process (GO:0046950)3.21316831
32protein targeting to Golgi (GO:0000042)3.19496459
33negative regulation of meiosis (GO:0045835)3.17655850
34L-methionine biosynthetic process from methylthioadenosine (GO:0019509)3.16429836
35epithelial cilium movement (GO:0003351)3.07149430
36lung secretory cell differentiation (GO:0061140)3.05823076
37regulation of ER to Golgi vesicle-mediated transport (GO:0060628)3.04459599
38plasma membrane fusion (GO:0045026)3.04328215
39regulation of digestive system process (GO:0044058)3.02161805
40positive regulation of renal sodium excretion (GO:0035815)2.99069067
41regulation of energy homeostasis (GO:2000505)2.96568779
42mitochondrial ATP synthesis coupled proton transport (GO:0042776)2.94844916
43G-protein coupled glutamate receptor signaling pathway (GO:0007216)2.93768026
44detection of light stimulus involved in visual perception (GO:0050908)2.92939989
45detection of light stimulus involved in sensory perception (GO:0050962)2.92939989
46negative regulation of heart rate (GO:0010459)2.89641369
47positive regulation of vesicle fusion (GO:0031340)2.87699248
48behavioral response to nicotine (GO:0035095)2.83666215
49GPI anchor metabolic process (GO:0006505)2.82072307
50centriole replication (GO:0007099)2.82032752
51ketone body metabolic process (GO:1902224)2.81066309
52photoreceptor cell maintenance (GO:0045494)2.80668059
53response to pain (GO:0048265)2.79783187
54intestinal cholesterol absorption (GO:0030299)2.78589643
55behavioral fear response (GO:0001662)2.78343005
56behavioral defense response (GO:0002209)2.78343005
57lens fiber cell development (GO:0070307)2.75844363
58prenylation (GO:0097354)2.72784344
59protein prenylation (GO:0018342)2.72784344
60spermatid nucleus differentiation (GO:0007289)2.72601257
61RNA phosphodiester bond hydrolysis, exonucleolytic (GO:0090503)2.71484010
62cilium movement (GO:0003341)2.69145723
63positive regulation of inositol phosphate biosynthetic process (GO:0060732)2.68855798
64regulation of synaptic transmission, GABAergic (GO:0032228)2.67287506
65ectoderm development (GO:0007398)2.66903327
66nucleobase catabolic process (GO:0046113)2.65619382
67nonmotile primary cilium assembly (GO:0035058)2.65541172
68single strand break repair (GO:0000012)2.65047922
69retrograde transport, vesicle recycling within Golgi (GO:0000301)2.64277025
70immunoglobulin mediated immune response (GO:0016064)2.64088344
71synapsis (GO:0007129)2.61838987
72negative regulation of response to food (GO:0032096)2.60614812
73negative regulation of appetite (GO:0032099)2.60614812
74eating behavior (GO:0042755)2.59749143
75protein localization to Golgi apparatus (GO:0034067)2.59394854
76positive regulation of growth hormone secretion (GO:0060124)2.58724852
77cornea development in camera-type eye (GO:0061303)2.58516068
78regulation of glucokinase activity (GO:0033131)2.57535743
79regulation of hexokinase activity (GO:1903299)2.57535743
80neuronal action potential (GO:0019228)2.57297835
81multicellular organismal response to stress (GO:0033555)2.56852238
82positive regulation of amino acid transport (GO:0051957)2.56619141
83amino acid salvage (GO:0043102)2.56481656
84L-methionine salvage (GO:0071267)2.56481656
85L-methionine biosynthetic process (GO:0071265)2.56481656
86histone H2A acetylation (GO:0043968)2.56378507
87righting reflex (GO:0060013)2.54527552
88regulation of renal sodium excretion (GO:0035813)2.53708788
89relaxation of smooth muscle (GO:0044557)2.52219644
90negative regulation of meiotic cell cycle (GO:0051447)2.48533003
91positive regulation of insulin secretion involved in cellular response to glucose stimulus (GO:003572.47889429
92regulation of establishment or maintenance of cell polarity (GO:0032878)2.47498254
93organelle disassembly (GO:1903008)2.47132965
94phospholipase C-activating G-protein coupled receptor signaling pathway (GO:0007200)2.45467373
95adult feeding behavior (GO:0008343)2.44056924
96intraciliary transport (GO:0042073)2.42650317
97prostate gland growth (GO:0060736)2.42160206
98respiratory chain complex IV assembly (GO:0008535)2.39907564
99somite development (GO:0061053)2.39805489
100tachykinin receptor signaling pathway (GO:0007217)10.4529432

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1EZH2_22144423_ChIP-Seq_EOC_Human3.99101390
2ZNF274_21170338_ChIP-Seq_K562_Hela3.31358658
3VDR_22108803_ChIP-Seq_LS180_Human3.11369711
4GBX2_23144817_ChIP-Seq_PC3_Human2.96820311
5GLI1_17442700_ChIP-ChIP_MESCs_Mouse2.86833145
6POU3F2_20337985_ChIP-ChIP_501MEL_Human2.75749844
7IGF1R_20145208_ChIP-Seq_DFB_Human2.62607716
8TAF15_26573619_Chip-Seq_HEK293_Human2.58227201
9FLI1_27457419_Chip-Seq_LIVER_Mouse2.36774977
10GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse2.36650698
11ZFP57_27257070_Chip-Seq_ESCs_Mouse2.33099726
12CEBPD_23245923_ChIP-Seq_MEFs_Mouse2.29682066
13IRF4_20064451_ChIP-Seq_CD4+T_Mouse2.24050352
14CBP_20019798_ChIP-Seq_JUKART_Human2.24050352
15SALL1_21062744_ChIP-ChIP_HESCs_Human2.17915000
16CTBP1_25329375_ChIP-Seq_LNCAP_Human2.15725377
17AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human2.14797505
18FUS_26573619_Chip-Seq_HEK293_Human2.11010808
19EWS_26573619_Chip-Seq_HEK293_Human2.09951110
20PCGF2_27294783_Chip-Seq_ESCs_Mouse2.08002274
21P300_19829295_ChIP-Seq_ESCs_Human2.07590012
22CTBP2_25329375_ChIP-Seq_LNCAP_Human2.06483922
23PCGF2_27294783_Chip-Seq_NPCs_Mouse2.03980697
24MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse1.84042708
25PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.83341620
26RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.82831978
27SMAD4_21799915_ChIP-Seq_A2780_Human1.72610410
28MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.70970300
29TP53_22573176_ChIP-Seq_HFKS_Human1.67238601
30AR_25329375_ChIP-Seq_VCAP_Human1.67188646
31HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse1.66979588
32SUZ12_27294783_Chip-Seq_NPCs_Mouse1.63282688
33UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human1.62732336
34ER_23166858_ChIP-Seq_MCF-7_Human1.59299893
35HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human1.58932698
36NR3C1_21868756_ChIP-Seq_MCF10A_Human1.54273431
37ELK1_19687146_ChIP-ChIP_HELA_Human1.52932742
38STAT3_23295773_ChIP-Seq_U87_Human1.49903489
39EZH2_27294783_Chip-Seq_NPCs_Mouse1.48739705
40SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.46916535
41GABP_17652178_ChIP-ChIP_JURKAT_Human1.46328874
42PIAS1_25552417_ChIP-Seq_VCAP_Human1.45478153
43CHD7_19251738_ChIP-ChIP_MESCs_Mouse1.44615711
44RNF2_27304074_Chip-Seq_NSC_Mouse1.43252296
45NFE2_27457419_Chip-Seq_LIVER_Mouse1.43023428
46CDX2_19796622_ChIP-Seq_MESCs_Mouse1.42313235
47TCF4_23295773_ChIP-Seq_U87_Human1.39757535
48MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human1.38837805
49SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.38678808
50NANOG_19829295_ChIP-Seq_ESCs_Human1.36851389
51SOX2_19829295_ChIP-Seq_ESCs_Human1.36851389
52TCF4_22108803_ChIP-Seq_LS180_Human1.36388371
53BCAT_22108803_ChIP-Seq_LS180_Human1.36160229
54OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.35998258
55EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human1.35360159
56TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse1.34894136
57PRDM14_20953172_ChIP-Seq_ESCs_Human1.34456197
58CBX2_27304074_Chip-Seq_ESCs_Mouse1.34302422
59TP53_16413492_ChIP-PET_HCT116_Human1.34273183
60KLF5_20875108_ChIP-Seq_MESCs_Mouse1.33829141
61EST1_17652178_ChIP-ChIP_JURKAT_Human1.33475410
62CRX_20693478_ChIP-Seq_RETINA_Mouse1.32977642
63TOP2B_26459242_ChIP-Seq_MCF-7_Human1.31780196
64TP63_19390658_ChIP-ChIP_HaCaT_Human1.27776829
65CDX2_21402776_ChIP-Seq_INTESTINAL-VILLUS_Mouse1.27684288
66SMAD3_21741376_ChIP-Seq_EPCs_Human1.26863132
67NANOG_18555785_Chip-Seq_ESCs_Mouse1.24722687
68RUNX2_22187159_ChIP-Seq_PCA_Human1.24137378
69EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse1.22571535
70HOXD13_18407260_ChIP-ChIP_DEVELOPING-LIMBS_Mouse1.22237237
71FLI1_21867929_ChIP-Seq_TH2_Mouse1.21839444
72E2F1_18555785_Chip-Seq_ESCs_Mouse1.21382861
73P53_22387025_ChIP-Seq_ESCs_Mouse1.13506123
74SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.13128256
75SMAD4_21741376_ChIP-Seq_EPCs_Human1.11574030
76SUZ12_18555785_Chip-Seq_ESCs_Mouse1.09560569
77VDR_23849224_ChIP-Seq_CD4+_Human1.08682136
78CMYC_18555785_Chip-Seq_ESCs_Mouse1.07615556
79CDX2_22108803_ChIP-Seq_LS180_Human1.07420346
80RXR_22108803_ChIP-Seq_LS180_Human1.02149953
81TAL1_26923725_Chip-Seq_HPCs_Mouse1.01716149
82FOXM1_26456572_ChIP-Seq_MCF-7_Human1.01505928
83STAT3_18555785_Chip-Seq_ESCs_Mouse1.01334732
84OCT4_21477851_ChIP-Seq_ESCs_Mouse1.00657992
85REST_21632747_ChIP-Seq_MESCs_Mouse1.00003831
86SALL4_22934838_ChIP-ChIP_CD34+_Human0.99924796
87SOX6_21985497_ChIP-Seq_MYOTUBES_Mouse0.99713615
88NFE2L2_20460467_ChIP-Seq_MEFs_Mouse0.99503326
89NRF2_20460467_ChIP-Seq_MEFs_Mouse0.99503326
90FOXA1_25329375_ChIP-Seq_VCAP_Human0.99205793
91FOXA1_27270436_Chip-Seq_PROSTATE_Human0.99205793
92GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse0.97306321
93GATA3_21878914_ChIP-Seq_MCF-7_Human0.96523324
94TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse0.96506470
95BMI1_23680149_ChIP-Seq_NPCS_Mouse0.94093798
96CEBPD_21427703_ChIP-Seq_3T3-L1_Mouse0.93887286
97TAL1_21186366_ChIP-Seq_BM-HSCs_Mouse0.93815119
98TEAD4_22529382_ChIP-Seq_TROPHECTODERM_Mouse0.93332823
99P300_18555785_Chip-Seq_ESCs_Mouse0.93328602
100ETV1_20927104_ChIP-Seq_GIST48_Human0.92230360

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0001529_abnormal_vocalization3.96360211
2MP0002736_abnormal_nociception_after3.80942697
3MP0000569_abnormal_digit_pigmentation3.75680140
4MP0002277_abnormal_respiratory_mucosa3.61849314
5MP0003195_calcinosis3.40505587
6MP0005645_abnormal_hypothalamus_physiol3.16430424
7MP0002735_abnormal_chemical_nociception3.15489141
8MP0001968_abnormal_touch/_nociception3.14064591
9MP0008877_abnormal_DNA_methylation3.00064670
10MP0002139_abnormal_hepatobiliary_system2.96671587
11MP0003646_muscle_fatigue2.89713873
12MP0003787_abnormal_imprinting2.66061813
13MP0008995_early_reproductive_senescence2.02410618
14MP0009780_abnormal_chondrocyte_physiolo1.99423373
15MP0002734_abnormal_mechanical_nocicepti1.95647324
16MP0008872_abnormal_physiological_respon1.87070820
17MP0002876_abnormal_thyroid_physiology1.85903009
18MP0005253_abnormal_eye_physiology1.81813639
19MP0005394_taste/olfaction_phenotype1.77650772
20MP0005499_abnormal_olfactory_system1.77650772
21MP0001764_abnormal_homeostasis1.73075230
22MP0009046_muscle_twitch1.73031701
23MP0008789_abnormal_olfactory_epithelium1.72762891
24MP0002272_abnormal_nervous_system1.69602390
25MP0001970_abnormal_pain_threshold1.62415979
26MP0006276_abnormal_autonomic_nervous1.57573387
27MP0002102_abnormal_ear_morphology1.57107908
28MP0004142_abnormal_muscle_tone1.55056627
29MP0003011_delayed_dark_adaptation1.54961790
30MP0001984_abnormal_olfaction1.54423138
31MP0005551_abnormal_eye_electrophysiolog1.54288700
32MP0009745_abnormal_behavioral_response1.50872423
33MP0005410_abnormal_fertilization1.50376451
34MP0005085_abnormal_gallbladder_physiolo1.49438286
35MP0001542_abnormal_bone_strength1.49292236
36MP0002933_joint_inflammation1.46924807
37MP0006054_spinal_hemorrhage1.41527444
38MP0000372_irregular_coat_pigmentation1.41287300
39MP0004147_increased_porphyrin_level1.32772646
40MP0005646_abnormal_pituitary_gland1.29700372
41MP0002638_abnormal_pupillary_reflex1.25973553
42MP0002163_abnormal_gland_morphology1.23372315
43MP0001501_abnormal_sleep_pattern1.23240172
44MP0004924_abnormal_behavior1.23117325
45MP0005386_behavior/neurological_phenoty1.23117325
46MP0003045_fibrosis1.22556320
47MP0002234_abnormal_pharynx_morphology1.22155586
48MP0006072_abnormal_retinal_apoptosis1.22130493
49MP0008057_abnormal_DNA_replication1.19852893
50MP0003880_abnormal_central_pattern1.17258232
51MP0004145_abnormal_muscle_electrophysio1.16074085
52MP0003122_maternal_imprinting1.09117791
53MP0003633_abnormal_nervous_system1.07646469
54MP0002572_abnormal_emotion/affect_behav1.06910723
55MP0005084_abnormal_gallbladder_morpholo1.05956629
56MP0001502_abnormal_circadian_rhythm1.03110985
57MP0000778_abnormal_nervous_system1.01748524
58MP0005535_abnormal_body_temperature0.99959614
59MP0003631_nervous_system_phenotype0.98434284
60MP0002067_abnormal_sensory_capabilities0.95497539
61MP0003186_abnormal_redox_activity0.95358617
62MP0002751_abnormal_autonomic_nervous0.95038725
63MP0004885_abnormal_endolymph0.94151955
64MP0002168_other_aberrant_phenotype0.93872020
65MP0001440_abnormal_grooming_behavior0.93170125
66MP0000230_abnormal_systemic_arterial0.90076136
67MP0001666_abnormal_nutrient_absorption0.89412308
68MP0003121_genomic_imprinting0.89305888
69MP0009697_abnormal_copulation0.87372056
70MP0002090_abnormal_vision0.87226271
71MP0001486_abnormal_startle_reflex0.85674422
72MP0009764_decreased_sensitivity_to0.84173061
73MP0002938_white_spotting0.83768922
74MP0003698_abnormal_male_reproductive0.81500724
75MP0004043_abnormal_pH_regulation0.80865568
76MP0003221_abnormal_cardiomyocyte_apopto0.80420165
77MP0002233_abnormal_nose_morphology0.80220890
78MP0005389_reproductive_system_phenotype0.79749693
79MP0004883_abnormal_blood_vessel0.79693855
80MP0002557_abnormal_social/conspecific_i0.79668962
81MP0008875_abnormal_xenobiotic_pharmacok0.79108829
82MP0002064_seizures0.78800169
83MP0002160_abnormal_reproductive_system0.78764596
84MP0002733_abnormal_thermal_nociception0.75865350
85MP0004133_heterotaxia0.75772117
86MP0003786_premature_aging0.75184162
87MP0005195_abnormal_posterior_eye0.73961319
88MP0005376_homeostasis/metabolism_phenot0.73790456
89MP0004270_analgesia0.71412461
90MP0003632_abnormal_nervous_system0.71044752
91MP0003635_abnormal_synaptic_transmissio0.71040489
92MP0008058_abnormal_DNA_repair0.70790749
93MP0001929_abnormal_gametogenesis0.70617082
94MP0010329_abnormal_lipoprotein_level0.70498665
95MP0003315_abnormal_perineum_morphology0.70207574
96MP0008775_abnormal_heart_ventricle0.67236437
97MP0008961_abnormal_basal_metabolism0.66973313
98MP0005395_other_phenotype0.66322713
99MP0005379_endocrine/exocrine_gland_phen0.65736257
100MP0004484_altered_response_of0.64718479

Predicted human phenotypes

RankGene SetZ-score
1Thyroiditis (HP:0100646)4.22456636
2Increased hepatocellular lipid droplets (HP:0006565)4.17858164
3Lipid accumulation in hepatocytes (HP:0006561)4.00704583
4Medial flaring of the eyebrow (HP:0010747)3.75559718
5Hypoproteinemia (HP:0003075)3.61117827
6Gait imbalance (HP:0002141)3.34580176
7Thyroid-stimulating hormone excess (HP:0002925)3.31436985
8Severe combined immunodeficiency (HP:0004430)3.26694380
9Pancreatic cysts (HP:0001737)3.11314849
10Absent speech (HP:0001344)3.04143231
11Congenital stationary night blindness (HP:0007642)2.98899009
12Fibular aplasia (HP:0002990)2.88371951
13Congenital primary aphakia (HP:0007707)2.88243949
14Absent rod-and cone-mediated responses on ERG (HP:0007688)2.85726739
15Mitochondrial inheritance (HP:0001427)2.82126667
16Type II lissencephaly (HP:0007260)2.78749841
17Renal Fanconi syndrome (HP:0001994)2.72162248
18Polyphagia (HP:0002591)2.71820756
19Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688)2.66061616
20Increased CSF lactate (HP:0002490)2.58449085
21Abnormal number of erythroid precursors (HP:0012131)2.58340874
22Molar tooth sign on MRI (HP:0002419)2.49480533
23Abnormality of midbrain morphology (HP:0002418)2.49480533
24Aplasia/Hypoplasia of the tibia (HP:0005772)2.49122243
25Abnormality of renal resorption (HP:0011038)2.47338986
26Exertional dyspnea (HP:0002875)2.46416671
27Focal motor seizures (HP:0011153)2.44918038
28Abnormality of B cell number (HP:0010975)2.44473088
29Nephrogenic diabetes insipidus (HP:0009806)2.42743651
30Cerebellar dysplasia (HP:0007033)2.42513569
31Chronic sinusitis (HP:0011109)2.41293605
32B lymphocytopenia (HP:0010976)2.40208358
33Congenital, generalized hypertrichosis (HP:0004540)2.36625044
34Respiratory difficulties (HP:0002880)2.36431204
35Methylmalonic acidemia (HP:0002912)2.34837170
36Hypothermia (HP:0002045)2.33791029
37Pancreatic fibrosis (HP:0100732)2.33244274
38Abnormality of the phalanges of the 2nd finger (HP:0009541)2.32801297
39Increased intramyocellular lipid droplets (HP:0012240)2.31927627
40Constricted visual fields (HP:0001133)2.30695904
41Abnormality of the renal medulla (HP:0100957)2.30612065
42Combined immunodeficiency (HP:0005387)2.29261074
43Abnormality of the renal cortex (HP:0011035)2.27863429
44Abolished electroretinogram (ERG) (HP:0000550)2.27773846
45Hepatocellular necrosis (HP:0001404)2.27318647
46True hermaphroditism (HP:0010459)2.24847275
47Nephronophthisis (HP:0000090)2.23593707
48Dyschromatopsia (HP:0007641)2.23589100
49Abnormal respiratory motile cilium morphology (HP:0005938)2.22982503
50Abnormal respiratory epithelium morphology (HP:0012253)2.22982503
51Gaze-evoked nystagmus (HP:0000640)2.22647586
52Abnormality of cells of the erythroid lineage (HP:0012130)2.19361375
53Testicular atrophy (HP:0000029)2.15820129
54Broad-based gait (HP:0002136)2.15027556
55Intestinal atresia (HP:0011100)2.14112797
56Short foot (HP:0001773)2.12644459
57Abnormal ciliary motility (HP:0012262)2.11931303
58Abnormal hair whorl (HP:0010721)2.11621808
59Renal cortical cysts (HP:0000803)2.11432012
60Vaginal atresia (HP:0000148)2.10019809
61Hepatic necrosis (HP:0002605)2.08488332
62Attenuation of retinal blood vessels (HP:0007843)2.08159027
63Hypoplasia of the thymus (HP:0000778)2.05939792
64Abnormality of the pons (HP:0007361)2.05733475
65Genital tract atresia (HP:0001827)2.05504766
663-Methylglutaconic aciduria (HP:0003535)2.05184483
67Bony spicule pigmentary retinopathy (HP:0007737)2.05107706
68Abnormal rod and cone electroretinograms (HP:0008323)2.03558324
69Diplopia (HP:0000651)2.02163217
70Abnormality of binocular vision (HP:0011514)2.02163217
71Hypoplasia of the pons (HP:0012110)2.01915299
72Facial diplegia (HP:0001349)2.01521762
73Facial cleft (HP:0002006)2.00947359
74Increased serum lactate (HP:0002151)1.99460651
75Hypoplasia of the uterus (HP:0000013)1.95852736
76Postaxial foot polydactyly (HP:0001830)1.91371445
77Muscle abnormality related to mitochondrial dysfunction (HP:0003800)1.87899438
78Short tibia (HP:0005736)1.87496986
79Postaxial hand polydactyly (HP:0001162)1.86987346
80Long clavicles (HP:0000890)1.83928899
81Increased muscle lipid content (HP:0009058)1.83813480
82Poikilocytosis (HP:0004447)1.83685662
83Acute necrotizing encephalopathy (HP:0006965)1.82817937
84Decreased central vision (HP:0007663)1.82531350
85Progressive inability to walk (HP:0002505)1.81461367
86Abnormality of the proximal phalanges of the hand (HP:0009834)1.80619413
87Progressive macrocephaly (HP:0004481)1.79400218
88Hyperkalemia (HP:0002153)1.77639553
89Dyskinesia (HP:0100660)1.76933974
90Abnormality of eosinophils (HP:0001879)1.76907863
91Abnormality of the pubic bones (HP:0003172)1.75942318
92Abnormality of the alveolar ridges (HP:0006477)1.75155108
93Inability to walk (HP:0002540)1.75094213
94Absent/shortened dynein arms (HP:0200106)1.74925197
95Dynein arm defect of respiratory motile cilia (HP:0012255)1.74925197
96Febrile seizures (HP:0002373)1.74699731
97Rimmed vacuoles (HP:0003805)1.74498589
98Abnormal respiratory motile cilium physiology (HP:0012261)1.72932984
99Abnormality of the epiphyses of the phalanges of the hand (HP:0005920)1.72228059
100Hemiparesis (HP:0001269)1.72027472

Predicted kinase interactions (KEA)

RankGene SetZ-score
1FRK5.04769711
2MAPK133.95339973
3BRSK22.84314804
4BMPR1B2.60874363
5BMPR22.59323806
6WNK42.44866959
7BCR2.28449925
8TNIK2.08861383
9DAPK22.08587649
10WNK31.99516688
11CASK1.95267242
12ZAK1.90910251
13MAP3K41.87891498
14MKNK21.85057976
15NTRK31.74148688
16PNCK1.60816102
17MARK11.59832781
18FLT31.58659420
19PLK21.57917274
20BCKDK1.54519697
21ACVR1B1.50838642
22CAMKK21.40149379
23MKNK11.38319603
24GRK11.37677321
25MAP4K21.36893274
26EIF2AK31.32950282
27GRK61.24864592
28KIT1.24621114
29ERBB31.21346433
30DYRK31.20647504
31STK391.18799833
32TEC1.15635412
33WNK11.12866324
34NUAK11.12688826
35ADRBK21.11209561
36MAP3K121.10890711
37PRKCE1.09825257
38TRPM71.07978133
39TAOK31.07428678
40PHKG21.01960134
41PHKG11.01960134
42SGK20.96193961
43PRKCG0.92636761
44OXSR10.91775095
45STK160.91172344
46DYRK20.90765753
47PAK30.89921117
48ADRBK10.88453046
49MAP2K70.88045574
50CDK190.85773660
51WEE10.85511670
52CSF1R0.76814169
53CLK10.76512697
54INSRR0.75164414
55TRIM280.75124297
56CSNK1G20.69860784
57PTK2B0.69697728
58SCYL20.67865217
59CSNK1A1L0.67419971
60PKN10.66712671
61EPHA40.65566042
62SYK0.65090849
63STK110.63860200
64CSNK1G10.62059137
65NEK90.61331324
66SGK2230.60539871
67SGK4940.60539871
68MAP3K20.58763642
69TGFBR10.56128884
70CSNK1G30.55616295
71PINK10.54707777
72PLK40.52908718
73MST40.52827655
74BRD40.52643419
75PRKG10.52544461
76PLK30.52238252
77SGK10.51080532
78MAP2K40.49779626
79BRSK10.46772175
80RPS6KA50.45939569
81CAMK10.45635141
82CAMK2A0.45514068
83VRK10.44947696
84ERBB20.43877956
85NLK0.42243788
86RPS6KA40.41909941
87PIK3CG0.41595326
88CSNK1A10.41121525
89AKT30.39239672
90PRKCQ0.37819045
91CAMK1G0.36934303
92OBSCN0.35300340
93MINK10.34609660
94GSK3A0.34490134
95CSNK1D0.32508282
96DYRK1A0.31737124
97PIK3CA0.31621501
98PRKACA0.31584344
99CAMK2D0.31328089
100BTK0.30504626

Predicted pathways (KEGG)

RankGene SetZ-score
1Asthma_Homo sapiens_hsa053104.53692595
2Allograft rejection_Homo sapiens_hsa053303.75351660
3Graft-versus-host disease_Homo sapiens_hsa053323.69475774
4Intestinal immune network for IgA production_Homo sapiens_hsa046723.63484486
5Autoimmune thyroid disease_Homo sapiens_hsa053203.63186567
6Type I diabetes mellitus_Homo sapiens_hsa049403.45104371
7Nitrogen metabolism_Homo sapiens_hsa009103.26480782
8Non-homologous end-joining_Homo sapiens_hsa034503.01072942
9Oxidative phosphorylation_Homo sapiens_hsa001902.26624797
10Protein export_Homo sapiens_hsa030602.04149282
11Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005631.84454700
12ABC transporters_Homo sapiens_hsa020101.84374230
13Phototransduction_Homo sapiens_hsa047441.73086918
14Staphylococcus aureus infection_Homo sapiens_hsa051501.66690908
15Synthesis and degradation of ketone bodies_Homo sapiens_hsa000721.62532923
16Inflammatory bowel disease (IBD)_Homo sapiens_hsa053211.61025780
17Parkinsons disease_Homo sapiens_hsa050121.60242235
18Viral myocarditis_Homo sapiens_hsa054161.59890032
19Linoleic acid metabolism_Homo sapiens_hsa005911.58305780
20SNARE interactions in vesicular transport_Homo sapiens_hsa041301.56764355
21Butanoate metabolism_Homo sapiens_hsa006501.55597742
22Huntingtons disease_Homo sapiens_hsa050161.55305331
23Circadian rhythm_Homo sapiens_hsa047101.49162832
24alpha-Linolenic acid metabolism_Homo sapiens_hsa005921.46484516
25Rheumatoid arthritis_Homo sapiens_hsa053231.45018689
26Ether lipid metabolism_Homo sapiens_hsa005651.42062864
27Antigen processing and presentation_Homo sapiens_hsa046121.37039687
28Regulation of autophagy_Homo sapiens_hsa041401.32073595
29Taste transduction_Homo sapiens_hsa047421.31976873
30Systemic lupus erythematosus_Homo sapiens_hsa053221.27043904
31Nicotine addiction_Homo sapiens_hsa050331.24784396
32Neuroactive ligand-receptor interaction_Homo sapiens_hsa040801.24731152
33Primary bile acid biosynthesis_Homo sapiens_hsa001201.23411703
34Olfactory transduction_Homo sapiens_hsa047401.22266846
35Homologous recombination_Homo sapiens_hsa034401.14975525
36Alzheimers disease_Homo sapiens_hsa050101.14219316
37RNA degradation_Homo sapiens_hsa030181.11268760
38Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049321.07550826
39Fat digestion and absorption_Homo sapiens_hsa049751.06607291
40Cell adhesion molecules (CAMs)_Homo sapiens_hsa045141.02724608
41Taurine and hypotaurine metabolism_Homo sapiens_hsa004301.02391394
42Propanoate metabolism_Homo sapiens_hsa006401.00074284
43Cardiac muscle contraction_Homo sapiens_hsa042600.98599003
44Valine, leucine and isoleucine degradation_Homo sapiens_hsa002800.93275158
45Maturity onset diabetes of the young_Homo sapiens_hsa049500.92274251
46Leishmaniasis_Homo sapiens_hsa051400.90346110
47Peroxisome_Homo sapiens_hsa041460.86408796
48Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001300.83374229
49Chemical carcinogenesis_Homo sapiens_hsa052040.74770609
50Ribosome_Homo sapiens_hsa030100.73998304
51Caffeine metabolism_Homo sapiens_hsa002320.73921741
52Drug metabolism - cytochrome P450_Homo sapiens_hsa009820.73529499
53RNA polymerase_Homo sapiens_hsa030200.71322453
54Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.70307341
55Circadian entrainment_Homo sapiens_hsa047130.68404636
56Glutamatergic synapse_Homo sapiens_hsa047240.64664170
57Morphine addiction_Homo sapiens_hsa050320.64283536
58Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.61413787
59Basal transcription factors_Homo sapiens_hsa030220.61078305
60Tryptophan metabolism_Homo sapiens_hsa003800.60803490
61Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.60470054
62GABAergic synapse_Homo sapiens_hsa047270.54068357
63Steroid hormone biosynthesis_Homo sapiens_hsa001400.52463979
64Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.52260299
65Calcium signaling pathway_Homo sapiens_hsa040200.51347213
66Primary immunodeficiency_Homo sapiens_hsa053400.48652643
67Dorso-ventral axis formation_Homo sapiens_hsa043200.45348032
68Long-term depression_Homo sapiens_hsa047300.43256595
69beta-Alanine metabolism_Homo sapiens_hsa004100.42966988
70Mineral absorption_Homo sapiens_hsa049780.42512695
71Tyrosine metabolism_Homo sapiens_hsa003500.41279584
72Retrograde endocannabinoid signaling_Homo sapiens_hsa047230.40164085
73Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.37576452
74Steroid biosynthesis_Homo sapiens_hsa001000.37249472
75RNA transport_Homo sapiens_hsa030130.36644285
76Retinol metabolism_Homo sapiens_hsa008300.36003594
77Vitamin B6 metabolism_Homo sapiens_hsa007500.35688844
78Phagosome_Homo sapiens_hsa041450.35184403
79Transcriptional misregulation in cancer_Homo sapiens_hsa052020.35058567
80Arachidonic acid metabolism_Homo sapiens_hsa005900.33919922
81Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.32513337
82Insulin secretion_Homo sapiens_hsa049110.32406961
83NOD-like receptor signaling pathway_Homo sapiens_hsa046210.31924352
84Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.31258421
85Ascorbate and aldarate metabolism_Homo sapiens_hsa000530.30995173
86Hematopoietic cell lineage_Homo sapiens_hsa046400.30853300
87Tuberculosis_Homo sapiens_hsa051520.29760737
88Fanconi anemia pathway_Homo sapiens_hsa034600.27620329
89p53 signaling pathway_Homo sapiens_hsa041150.26209764
90Salivary secretion_Homo sapiens_hsa049700.25935903
91Cysteine and methionine metabolism_Homo sapiens_hsa002700.24985030
92Ovarian steroidogenesis_Homo sapiens_hsa049130.24963424
93Toxoplasmosis_Homo sapiens_hsa051450.24471196
94Metabolic pathways_Homo sapiens_hsa011000.22869395
95Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049600.22746716
96Cytosolic DNA-sensing pathway_Homo sapiens_hsa046230.19394183
97Collecting duct acid secretion_Homo sapiens_hsa049660.18289331
98Fatty acid degradation_Homo sapiens_hsa000710.18199990
99Glycerophospholipid metabolism_Homo sapiens_hsa005640.17980661
100Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.15480071

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