SUV39H1

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: This gene encodes an evolutionarily-conserved protein containing an N-terminal chromodomain and a C-terminal SET domain. The encoded protein is a histone methyltransferase that trimethylates lysine 9 of histone H3, which results in transcriptional gene silencing. Loss of function of this gene disrupts heterochromatin formation and may cause chromosome instability. Alternative splicing results in multiple transcript variants. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1DNA unwinding involved in DNA replication (GO:0006268)5.68380669
2DNA strand elongation involved in DNA replication (GO:0006271)5.50616278
3DNA strand elongation (GO:0022616)5.25973192
4telomere maintenance via semi-conservative replication (GO:0032201)5.22793165
5protein localization to kinetochore (GO:0034501)5.21873690
6DNA replication initiation (GO:0006270)5.00994741
7regulation of sister chromatid cohesion (GO:0007063)4.94975829
8telomere maintenance via recombination (GO:0000722)4.72158275
9positive regulation of mitotic sister chromatid separation (GO:1901970)4.69622150
10positive regulation of mitotic metaphase/anaphase transition (GO:0045842)4.69622150
11positive regulation of metaphase/anaphase transition of cell cycle (GO:1902101)4.69622150
12mitotic recombination (GO:0006312)4.60763596
13DNA replication checkpoint (GO:0000076)4.54392537
14protein localization to chromosome, centromeric region (GO:0071459)4.44301441
15CENP-A containing nucleosome assembly (GO:0034080)4.36126796
16kinetochore organization (GO:0051383)4.32325352
17mitotic sister chromatid segregation (GO:0000070)4.30113511
18mitotic chromosome condensation (GO:0007076)4.28857984
19ribosomal small subunit assembly (GO:0000028)4.25964459
20chromatin remodeling at centromere (GO:0031055)4.24697731
21mitotic metaphase plate congression (GO:0007080)4.24227782
22nucleotide-excision repair, DNA gap filling (GO:0006297)4.19483759
23telomere maintenance via telomere lengthening (GO:0010833)4.13779039
24sister chromatid segregation (GO:0000819)4.09715278
25attachment of spindle microtubules to kinetochore (GO:0008608)4.06882649
26mitotic nuclear envelope disassembly (GO:0007077)4.02333233
27DNA replication-independent nucleosome assembly (GO:0006336)4.00531270
28DNA replication-independent nucleosome organization (GO:0034724)4.00531270
29regulation of translational fidelity (GO:0006450)3.94561414
30regulation of attachment of spindle microtubules to kinetochore (GO:0051988)3.83385880
31metaphase plate congression (GO:0051310)3.82660001
32DNA replication-dependent nucleosome organization (GO:0034723)3.78183336
33DNA replication-dependent nucleosome assembly (GO:0006335)3.78183336
34nuclear envelope disassembly (GO:0051081)3.72896277
35membrane disassembly (GO:0030397)3.72896277
36regulation of transcription involved in G1/S transition of mitotic cell cycle (GO:0000083)3.72230604
37double-strand break repair via nonhomologous end joining (GO:0006303)3.72143041
38non-recombinational repair (GO:0000726)3.72143041
39kinetochore assembly (GO:0051382)3.72112962
40maturation of SSU-rRNA (GO:0030490)3.71420416
41meiotic chromosome segregation (GO:0045132)3.68904565
42negative regulation of mRNA splicing, via spliceosome (GO:0048025)3.61536270
43viral transcription (GO:0019083)3.60945647
44nuclear pore organization (GO:0006999)3.60842551
45establishment of chromosome localization (GO:0051303)3.59521644
46histone exchange (GO:0043486)3.56965554
47translational termination (GO:0006415)3.56769402
48DNA duplex unwinding (GO:0032508)3.55849818
49DNA geometric change (GO:0032392)3.54281834
50nucleobase biosynthetic process (GO:0046112)3.51455884
51mitotic sister chromatid cohesion (GO:0007064)3.51013142
52negative regulation of RNA splicing (GO:0033119)3.48370969
53establishment of integrated proviral latency (GO:0075713)3.47868213
54IMP biosynthetic process (GO:0006188)3.47022608
55regulation of mammary gland epithelial cell proliferation (GO:0033599)3.47008389
563-UTR-mediated mRNA stabilization (GO:0070935)3.46297699
57nuclear pore complex assembly (GO:0051292)3.45298297
58regulation of spindle organization (GO:0090224)3.41723050
59folic acid-containing compound biosynthetic process (GO:0009396)3.41285013
60regulation of mitotic spindle organization (GO:0060236)3.40002185
61DNA topological change (GO:0006265)3.39529613
62regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:00450913.39164561
63formation of translation preinitiation complex (GO:0001731)3.33455326
64DNA ligation (GO:0006266)3.33074558
65spliceosomal tri-snRNP complex assembly (GO:0000244)3.31920905
66DNA synthesis involved in DNA repair (GO:0000731)3.31622351
67chromatin assembly or disassembly (GO:0006333)3.31150917
68proline biosynthetic process (GO:0006561)3.30305613
69spindle checkpoint (GO:0031577)3.29312021
70ribosomal large subunit biogenesis (GO:0042273)3.27827530
71negative regulation of chromosome segregation (GO:0051985)3.26791913
72regulation of chromosome segregation (GO:0051983)3.26506532
73spindle assembly checkpoint (GO:0071173)3.26430784
74regulation of double-strand break repair via homologous recombination (GO:0010569)3.24829376
75translesion synthesis (GO:0019985)3.24162466
76negative regulation of mitotic sister chromatid separation (GO:2000816)3.23836879
77negative regulation of mitotic sister chromatid segregation (GO:0033048)3.23836879
78negative regulation of mitotic metaphase/anaphase transition (GO:0045841)3.23836879
79negative regulation of sister chromatid segregation (GO:0033046)3.23836879
80translational elongation (GO:0006414)3.23315246
81protein complex localization (GO:0031503)3.23073425
82telomere maintenance (GO:0000723)3.22384723
83protein localization to chromosome (GO:0034502)3.22097435
84telomere organization (GO:0032200)3.20150928
85mitotic spindle assembly checkpoint (GO:0007094)3.19384595
86DNA packaging (GO:0006323)3.19201218
87chromosome segregation (GO:0007059)3.18914015
88base-excision repair (GO:0006284)3.17801603
89pore complex assembly (GO:0046931)3.15614170
90regulation of mitotic metaphase/anaphase transition (GO:0030071)3.14690459
91negative regulation of metaphase/anaphase transition of cell cycle (GO:1902100)3.14557823
92mismatch repair (GO:0006298)3.13749064
93nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184)3.13512431
94maintenance of fidelity involved in DNA-dependent DNA replication (GO:0045005)3.13355953
95DNA conformation change (GO:0071103)3.13281781
96ATP-dependent chromatin remodeling (GO:0043044)3.13171939
97translational initiation (GO:0006413)3.13143182
98positive regulation of chromosome segregation (GO:0051984)3.12429009
99purine nucleobase biosynthetic process (GO:0009113)3.11469403
100nucleobase-containing small molecule interconversion (GO:0015949)3.10546241
101IMP metabolic process (GO:0046040)3.09105926
102negative regulation of mRNA processing (GO:0050686)3.08600755
103regulation of metaphase/anaphase transition of cell cycle (GO:1902099)3.07728153
104postreplication repair (GO:0006301)3.06590474
105mitotic spindle checkpoint (GO:0071174)3.05924786
106ribosome assembly (GO:0042255)3.04296507
107mitochondrial RNA metabolic process (GO:0000959)3.04254357
108deoxyribonucleoside monophosphate metabolic process (GO:0009162)3.01354368
109heterochromatin organization (GO:0070828)3.00850114
110spliceosomal snRNP assembly (GO:0000387)3.00681655
111SRP-dependent cotranslational protein targeting to membrane (GO:0006614)3.00307187
112ribosomal small subunit biogenesis (GO:0042274)2.99228349
113regulation of sister chromatid segregation (GO:0033045)2.97779106
114regulation of mitotic sister chromatid separation (GO:0010965)2.97779106
115regulation of mitotic sister chromatid segregation (GO:0033047)2.97779106
116transcription-coupled nucleotide-excision repair (GO:0006283)2.95726755
117peptidyl-arginine omega-N-methylation (GO:0035247)2.95652227
118mitotic cell cycle (GO:0000278)2.95115161
119mRNA splicing, via spliceosome (GO:0000398)2.94771810
120RNA splicing, via transesterification reactions with bulged adenosine as nucleophile (GO:0000377)2.94771810
121spliceosomal complex assembly (GO:0000245)2.94169111
122chromosome condensation (GO:0030261)2.94135703
123RNA splicing, via transesterification reactions (GO:0000375)2.93749661
124cotranslational protein targeting to membrane (GO:0006613)2.93091560
125anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process (GO:02.88222580
126DNA strand renaturation (GO:0000733)2.87367037
127establishment of mitotic spindle localization (GO:0040001)2.85014777
128microtubule depolymerization (GO:0007019)2.84277710
129nuclear envelope organization (GO:0006998)2.84208487

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1FOXM1_23109430_ChIP-Seq_U2OS_Human5.37356524
2* E2F4_17652178_ChIP-ChIP_JURKAT_Human4.37218691
3MYC_18555785_ChIP-Seq_MESCs_Mouse3.96956304
4FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human3.71225692
5EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse3.66815998
6KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human2.87034181
7MYC_19079543_ChIP-ChIP_MESCs_Mouse2.74804385
8EST1_17652178_ChIP-ChIP_JURKAT_Human2.68255614
9* MYC_19030024_ChIP-ChIP_MESCs_Mouse2.60200575
10MYC_18358816_ChIP-ChIP_MESCs_Mouse2.59375908
11HCFC1_20581084_ChIP-Seq_MESCs_Mouse2.39771579
12AR_21909140_ChIP-Seq_LNCAP_Human2.39471254
13ETS1_20019798_ChIP-Seq_JURKAT_Human2.39139667
14CREB1_15753290_ChIP-ChIP_HEK293T_Human2.33082922
15* E2F1_21310950_ChIP-Seq_MCF-7_Human2.31564711
16GABP_17652178_ChIP-ChIP_JURKAT_Human2.29909922
17JARID1A_20064375_ChIP-Seq_MESCs_Mouse2.29708500
18XRN2_22483619_ChIP-Seq_HELA_Human2.28160307
19EGR1_19374776_ChIP-ChIP_THP-1_Human2.23701128
20NELFA_20434984_ChIP-Seq_ESCs_Mouse2.19869301
21MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse2.19171353
22ELF1_17652178_ChIP-ChIP_JURKAT_Human2.14066388
23MYC_22102868_ChIP-Seq_BL_Human2.06792504
24VDR_23849224_ChIP-Seq_CD4+_Human2.03884464
25FOXP3_21729870_ChIP-Seq_TREG_Human2.00256563
26E2F7_22180533_ChIP-Seq_HELA_Human10.4958607
27CHD1_19587682_ChIP-ChIP_MESCs_Mouse1.97472124
28MYBL2_22936984_ChIP-ChIP_MESCs_Mouse1.96200200
29NOTCH1_17114293_ChIP-ChIP_T-ALL_Human1.95776026
30MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.93105211
31TTF2_22483619_ChIP-Seq_HELA_Human1.88768286
32SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse1.86754988
33CIITA_25753668_ChIP-Seq_RAJI_Human1.85024542
34DCP1A_22483619_ChIP-Seq_HELA_Human1.83968895
35SOX9_22984422_ChIP-ChIP_TESTIS_Rat1.80563405
36THAP11_20581084_ChIP-Seq_MESCs_Mouse1.75877355
37KDM5B_21448134_ChIP-Seq_MESCs_Mouse1.75819317
38E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse1.75333109
39MYCN_18555785_ChIP-Seq_MESCs_Mouse1.74116215
40* E2F1_18555785_ChIP-Seq_MESCs_Mouse1.72900420
41TAL1_20887958_ChIP-Seq_HPC-7_Mouse1.72823400
42GABP_19822575_ChIP-Seq_HepG2_Human1.72761524
43PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse1.66265246
44HOXB4_20404135_ChIP-ChIP_EML_Mouse1.59829234
45* YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.57998523
46ELK1_19687146_ChIP-ChIP_HELA_Human1.57652417
47FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse1.54881726
48ZFX_18555785_ChIP-Seq_MESCs_Mouse1.52175364
49HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human1.52124367
50VDR_21846776_ChIP-Seq_THP-1_Human1.52096015
51POU5F1_18555785_ChIP-Seq_MESCs_Mouse1.49760239
52TP63_19390658_ChIP-ChIP_HaCaT_Human1.47391415
53ASXL1_24218140_ChIP-Seq_BMDM_Mouse1.47235567
54KDM5A_27292631_Chip-Seq_BREAST_Human1.47007084
55CCND1_20090754_ChIP-ChIP_RETINA_Mouse1.42495852
56SFPI1_20887958_ChIP-Seq_HPC-7_Mouse1.39994804
57HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse1.38484690
58ZNF263_19887448_ChIP-Seq_K562_Human1.37175573
59ERG_20887958_ChIP-Seq_HPC-7_Mouse1.36639101
60GATA1_22025678_ChIP-Seq_K562_Human1.35859979
61STAT3_1855785_ChIP-Seq_MESCs_Mouse1.34791080
62E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human1.34082156
63NANOG_18555785_ChIP-Seq_MESCs_Mouse1.32335310
64ZFP42_18358816_ChIP-ChIP_MESCs_Mouse1.31470214
65SPI1_22096565_ChIP-ChIP_GC-B_Mouse1.29912667
66RBPJ_22232070_ChIP-Seq_NCS_Mouse1.25459251
67YY1_21170310_ChIP-Seq_MESCs_Mouse1.25215248
68FLI1_20887958_ChIP-Seq_HPC-7_Mouse1.24626142
69* CEBPB_23403033_ChIP-Seq_LIVER_Mouse1.21131488
70SRF_21415370_ChIP-Seq_HL-1_Mouse1.17968776
71PADI4_21655091_ChIP-ChIP_MCF-7_Human1.12395960
72ELK3_25401928_ChIP-Seq_HUVEC_Human1.11909099
73KDM2B_26808549_Chip-Seq_SIL-ALL_Human1.11224841
74DACH1_20351289_ChIP-Seq_MDA-MB-231_Human1.10896268
75HSF1_23293686_ChIP-Seq_STHDH_STRIATAL_Mouse1.10230270
76MYC_18940864_ChIP-ChIP_HL60_Human1.08988272
77SRY_22984422_ChIP-ChIP_TESTIS_Rat1.08802355
78KLF4_18555785_ChIP-Seq_MESCs_Mouse1.06926601
79GFI1B_20887958_ChIP-Seq_HPC-7_Mouse1.05770798
80TFEB_21752829_ChIP-Seq_HELA_Human1.04992190
81SPI1_23547873_ChIP-Seq_NB4_Human1.04050714
82PPARG_19300518_ChIP-PET_3T3-L1_Mouse1.04003857
83LXR_22292898_ChIP-Seq_THP-1_Human1.03661565
84CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat1.01331398
85KLF4_18358816_ChIP-ChIP_MESCs_Mouse1.01151639
86NOTCH1_21737748_ChIP-Seq_TLL_Human0.99942524
87NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human0.99836517
88MAF_26560356_Chip-Seq_TH2_Human0.98400667
89KLF4_19030024_ChIP-ChIP_MESCs_Mouse0.97993417
90* CREM_20920259_ChIP-Seq_GC1-SPG_Mouse0.97630787
91CNOT3_19339689_ChIP-ChIP_MESCs_Mouse0.97446012
92ESR1_15608294_ChIP-ChIP_MCF-7_Human0.96000615
93SOX2_18555785_ChIP-Seq_MESCs_Mouse0.95341193
94CEBPA_23403033_ChIP-Seq_LIVER_Mouse0.94788972
95TET1_21451524_ChIP-Seq_MESCs_Mouse0.93671971
96CREB1_20920259_ChIP-Seq_GC1-SPG_Mouse0.92080332
97CEBPB_24764292_ChIP-Seq_MC3T3_Mouse0.91587995
98MECOM_23826213_ChIP-Seq_KASUMI_Mouse0.91253009
99RACK7_27058665_Chip-Seq_MCF-7_Human0.91028451
100NCOR1_26117541_ChIP-Seq_K562_Human0.89084218
101CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human0.89035878
102SIN3A_21632747_ChIP-Seq_MESCs_Mouse0.88867507
103ZFP281_18358816_ChIP-ChIP_MESCs_Mouse0.88300450
104UTX_26944678_Chip-Seq_JUKART_Human0.87395670
105TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse0.86581747
106TBX5_21415370_ChIP-Seq_HL-1_Mouse0.86571393
107POU5F1_18700969_ChIP-ChIP_MESCs_Mouse0.85916037
108* CUX1_19635798_ChIP-ChIP_MULTIPLE_HUMAN_CANCER_TYPES_Human0.84413904
109CHD1_26751641_Chip-Seq_LNCaP_Human0.84216579
110DMRT1_21621532_ChIP-ChIP_FETAL_Ovary0.84130266
111SCL_19346495_ChIP-Seq_HPC-7_Human0.83750879
112BCL3_23251550_ChIP-Seq_MUSCLE_Mouse0.83712030
113POU5F1_18358816_ChIP-ChIP_MESCs_Mouse0.81903806
114MYB_21317192_ChIP-Seq_ERMYB_Mouse0.79205060
115MAF_26560356_Chip-Seq_TH1_Human0.78314124
116PDX1_19855005_ChIP-ChIP_MIN6_Mouse0.78265648
117IRF8_22096565_ChIP-ChIP_GC-B_Mouse0.77367549
118MYB_26560356_Chip-Seq_TH2_Human0.75594807
119ASH2L_23239880_ChIP-Seq_MESCs_Mouse0.75357093
120NANOG_21062744_ChIP-ChIP_HESCs_Human0.75288455
121MYB_26560356_Chip-Seq_TH1_Human0.74935513
122GATA1_22383799_ChIP-Seq_G1ME_Mouse0.74222366
123FLI1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.71216328
124RUNX1_22412390_ChIP-Seq_EML_Mouse0.71142418
125VDR_24763502_ChIP-Seq_THP-1_Human0.71114043

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0010094_abnormal_chromosome_stability5.05531891
2MP0003693_abnormal_embryo_hatching4.91396932
3MP0003111_abnormal_nucleus_morphology4.65556477
4MP0008057_abnormal_DNA_replication4.21916935
5MP0003077_abnormal_cell_cycle4.10998917
6MP0004957_abnormal_blastocyst_morpholog4.07904901
7MP0008058_abnormal_DNA_repair3.34230754
8MP0002396_abnormal_hematopoietic_system3.34201396
9MP0008007_abnormal_cellular_replicative3.10809220
10MP0008932_abnormal_embryonic_tissue2.65935766
11MP0003303_peritoneal_inflammation2.45740293
12MP0002877_abnormal_melanocyte_morpholog2.28672437
13MP0000566_synostosis2.24537518
14MP0000350_abnormal_cell_proliferation2.21926053
15MP0008877_abnormal_DNA_methylation2.21707730
16MP0003123_paternal_imprinting2.15480040
17MP0001730_embryonic_growth_arrest2.15145703
18MP0003806_abnormal_nucleotide_metabolis2.09719829
19MP0004808_abnormal_hematopoietic_stem2.08975933
20MP0000490_abnormal_crypts_of1.99772004
21MP0010307_abnormal_tumor_latency1.92823912
22MP0005451_abnormal_body_composition1.80076123
23MP0003121_genomic_imprinting1.68866491
24MP0005380_embryogenesis_phenotype1.64695564
25MP0001672_abnormal_embryogenesis/_devel1.64695564
26MP0003786_premature_aging1.62549281
27MP0004233_abnormal_muscle_weight1.62107525
28* MP0001697_abnormal_embryo_size1.62036015
29MP0004185_abnormal_adipocyte_glucose1.60095499
30MP0009333_abnormal_splenocyte_physiolog1.55609780
31MP0005397_hematopoietic_system_phenotyp1.55347228
32MP0001545_abnormal_hematopoietic_system1.55347228
33* MP0002080_prenatal_lethality1.53807254
34MP0000313_abnormal_cell_death1.53590613
35MP0010352_gastrointestinal_tract_polyps1.53483302
36* MP0002019_abnormal_tumor_incidence1.52551528
37MP0003705_abnormal_hypodermis_morpholog1.50672801
38MP0003763_abnormal_thymus_physiology1.50516471
39MP0003984_embryonic_growth_retardation1.48133383
40MP0005501_abnormal_skin_physiology1.47531034
41MP0002398_abnormal_bone_marrow1.47525786
42MP0002085_abnormal_embryonic_tissue1.47259325
43MP0000703_abnormal_thymus_morphology1.45948000
44MP0002088_abnormal_embryonic_growth/wei1.43924025
45MP0006054_spinal_hemorrhage1.40883147
46MP0005076_abnormal_cell_differentiation1.40695517
47MP0002084_abnormal_developmental_patter1.34459568
48MP0002086_abnormal_extraembryonic_tissu1.28386604
49MP0002722_abnormal_immune_system1.27123443
50MP0004197_abnormal_fetal_growth/weight/1.25926704
51MP0010030_abnormal_orbit_morphology1.25108207
52MP0009053_abnormal_anal_canal1.23667420
53MP0001346_abnormal_lacrimal_gland1.23101916
54MP0000689_abnormal_spleen_morphology1.20221651
55MP0009278_abnormal_bone_marrow1.18940069
56MP0009379_abnormal_foot_pigmentation1.18716836
57MP0003567_abnormal_fetal_cardiomyocyte1.16695523
58MP0006035_abnormal_mitochondrial_morpho1.16283068
59MP0005058_abnormal_lysosome_morphology1.12708424
60MP0003453_abnormal_keratinocyte_physiol1.12243400
61MP0001661_extended_life_span1.11047476
62MP0000537_abnormal_urethra_morphology1.09845862
63MP0002429_abnormal_blood_cell1.08592303
64* MP0002210_abnormal_sex_determination1.08020690
65MP0005174_abnormal_tail_pigmentation1.07040884
66MP0005083_abnormal_biliary_tract1.03959772
67MP0001293_anophthalmia1.03621570
68MP0006036_abnormal_mitochondrial_physio1.02508122
69MP0002102_abnormal_ear_morphology1.02350752
70MP0002095_abnormal_skin_pigmentation1.02303986
71MP0003136_yellow_coat_color1.01917597
72MP0001919_abnormal_reproductive_system1.01313694
73MP0001145_abnormal_male_reproductive0.97529782
74MP0000716_abnormal_immune_system0.96666007
75MP0000678_abnormal_parathyroid_gland0.95738910
76MP0003315_abnormal_perineum_morphology0.94195756
77MP0009697_abnormal_copulation0.93974761
78MP0000858_altered_metastatic_potential0.93603215
79MP0003890_abnormal_embryonic-extraembry0.92138168
80MP0001849_ear_inflammation0.91014454
81MP0000467_abnormal_esophagus_morphology0.88875147
82MP0001119_abnormal_female_reproductive0.87404519
83MP0006292_abnormal_olfactory_placode0.87284678
84MP0008260_abnormal_autophagy0.86555230
85MP0000465_gastrointestinal_hemorrhage0.86042297
86MP0002132_abnormal_respiratory_system0.85524932
87MP0001727_abnormal_embryo_implantation0.85413557
88MP0000653_abnormal_sex_gland0.85061720
89* MP0001929_abnormal_gametogenesis0.82635459
90MP0009672_abnormal_birth_weight0.81039873
91MP0001800_abnormal_humoral_immune0.80754693
92MP0002420_abnormal_adaptive_immunity0.80598388
93MP0005075_abnormal_melanosome_morpholog0.79180608
94MP0001819_abnormal_immune_cell0.78824252
95MP0003937_abnormal_limbs/digits/tail_de0.77110080
96MP0001835_abnormal_antigen_presentation0.76471076
97MP0003943_abnormal_hepatobiliary_system0.76049762
98MP0004147_increased_porphyrin_level0.72766223
99MP0002111_abnormal_tail_morphology0.72690887
100MP0002796_impaired_skin_barrier0.72631728
101MP0005384_cellular_phenotype0.71737736
102MP0003718_maternal_effect0.71669919
103MP0002452_abnormal_antigen_presenting0.71552459
104MP0002249_abnormal_larynx_morphology0.70783658
105MP0003119_abnormal_digestive_system0.70353242
106MP0001873_stomach_inflammation0.69223956
107MP0005464_abnormal_platelet_physiology0.68939947
108MP0001915_intracranial_hemorrhage0.68914039
109MP0002938_white_spotting0.68906196
110MP0000015_abnormal_ear_pigmentation0.67950577
111MP0004381_abnormal_hair_follicle0.67819399
112MP0003656_abnormal_erythrocyte_physiolo0.67501310
113MP0005621_abnormal_cell_physiology0.67326270
114MP0009931_abnormal_skin_appearance0.67050967
115MP0005671_abnormal_response_to0.66262050
116MP0000428_abnormal_craniofacial_morphol0.65641777
117MP0009703_decreased_birth_body0.65195676
118MP0002405_respiratory_system_inflammati0.63692723
119MP0003566_abnormal_cell_adhesion0.62638158
120MP0005171_absent_coat_pigmentation0.62607808
121MP0003115_abnormal_respiratory_system0.62031572
122MP0001853_heart_inflammation0.61443048
123MP0002970_abnormal_white_adipose0.61440732
124MP0002160_abnormal_reproductive_system0.61328110
125MP0005666_abnormal_adipose_tissue0.60991909
126MP0000358_abnormal_cell_content/0.60710821
127MP0000477_abnormal_intestine_morphology0.60013598
128MP0002723_abnormal_immune_serum0.59204819
129MP0000049_abnormal_middle_ear0.59177920
130MP0003699_abnormal_female_reproductive0.58569221
131MP0002697_abnormal_eye_size0.57030889
132MP0002092_abnormal_eye_morphology0.56887827
133MP0000685_abnormal_immune_system0.56768020
134MP0003221_abnormal_cardiomyocyte_apopto0.55585596
135MP0003122_maternal_imprinting0.55315117
136MP0002075_abnormal_coat/hair_pigmentati0.54488448
137MP0005389_reproductive_system_phenotype0.53858294

Predicted human phenotypes

RankGene SetZ-score
1Chromsome breakage (HP:0040012)4.74025046
2Progressive muscle weakness (HP:0003323)4.59117557
3Chromosomal breakage induced by crosslinking agents (HP:0003221)4.55518225
4Reticulocytopenia (HP:0001896)4.32932486
5Birth length less than 3rd percentile (HP:0003561)4.31704223
6Abnormal number of erythroid precursors (HP:0012131)3.70661598
7Abnormality of cells of the erythroid lineage (HP:0012130)3.68768798
8Abnormality of long-chain fatty-acid metabolism (HP:0010964)3.60519042
9Abnormality of chromosome stability (HP:0003220)3.56450331
10Meckel diverticulum (HP:0002245)3.41776041
11Aplastic anemia (HP:0001915)3.38502801
12Aplasia/Hypoplasia of the uvula (HP:0010293)3.36312989
13Patellar aplasia (HP:0006443)3.36042433
14Abnormality of the preputium (HP:0100587)3.34684828
15Abnormality of the ileum (HP:0001549)3.30863245
16Myelodysplasia (HP:0002863)3.18111679
17Ureteral duplication (HP:0000073)3.17851750
18Colon cancer (HP:0003003)3.14678900
19Aplasia/Hypoplasia of the patella (HP:0006498)3.14015478
20Duodenal stenosis (HP:0100867)3.13656655
21Small intestinal stenosis (HP:0012848)3.13656655
22Oral leukoplakia (HP:0002745)3.00730801
23Selective tooth agenesis (HP:0001592)2.98188099
24Medulloblastoma (HP:0002885)2.96997671
25Increased nuchal translucency (HP:0010880)2.89224592
2611 pairs of ribs (HP:0000878)2.88040965
27Cholecystitis (HP:0001082)2.87360045
28Abnormal gallbladder physiology (HP:0012438)2.87360045
29Thrombocytosis (HP:0001894)2.85847759
30Microvesicular hepatic steatosis (HP:0001414)2.84542059
31Ectopic kidney (HP:0000086)2.81454700
32Volvulus (HP:0002580)2.77403310
33Breast hypoplasia (HP:0003187)2.70712048
34Pallor (HP:0000980)2.67053659
35Abnormal number of incisors (HP:0011064)2.66519038
36Bone marrow hypocellularity (HP:0005528)2.64193122
37Broad distal phalanx of finger (HP:0009836)2.62813484
38Abnormality of the carotid arteries (HP:0005344)2.59295621
39Abnormal lung lobation (HP:0002101)2.57508824
40Absent thumb (HP:0009777)2.56204193
41Degeneration of anterior horn cells (HP:0002398)2.53842095
42Abnormality of the anterior horn cell (HP:0006802)2.53842095
43Ragged-red muscle fibers (HP:0003200)2.49542129
44Abnormality of the duodenum (HP:0002246)2.45350953
45Macrocytic anemia (HP:0001972)2.44541117
46Sloping forehead (HP:0000340)2.43548553
47Progressive external ophthalmoplegia (HP:0000590)2.36956614
48Long foot (HP:0001833)2.35084060
49Short 4th metacarpal (HP:0010044)2.33022986
50Aplasia/Hypoplasia of the 4th metacarpal (HP:0010042)2.33022986
51Clubbing of toes (HP:0100760)2.32669590
52Nephroblastoma (Wilms tumor) (HP:0002667)2.25138091
53Triphalangeal thumb (HP:0001199)2.24003977
54Embryonal renal neoplasm (HP:0011794)2.22765052
55Rhabdomyosarcoma (HP:0002859)2.21901023
56Proximal placement of thumb (HP:0009623)2.19026597
57Hypoplasia of the capital femoral epiphysis (HP:0003090)2.18226212
58Basal cell carcinoma (HP:0002671)2.17835838
59High pitched voice (HP:0001620)2.17542084
60Deviation of the thumb (HP:0009603)2.16673714
61Atresia of the external auditory canal (HP:0000413)2.16622785
62Cafe-au-lait spot (HP:0000957)2.16437073
63Tracheoesophageal fistula (HP:0002575)2.15932525
64Septate vagina (HP:0001153)2.15517917
65Agnosia (HP:0010524)2.14298867
66Ependymoma (HP:0002888)2.12159679
67Premature graying of hair (HP:0002216)2.11600955
68Abnormality of the heme biosynthetic pathway (HP:0010472)2.10470406
69Hypoplastic pelvis (HP:0008839)2.09430324
70Neoplasm of the pancreas (HP:0002894)2.09250463
71Missing ribs (HP:0000921)2.07678153
72Slender long bone (HP:0003100)2.05732025
73Abnormality of the umbilical cord (HP:0010881)2.05431739
74Cholelithiasis (HP:0001081)2.04782709
75Prominent nose (HP:0000448)2.04663056
76Cerebral hypomyelination (HP:0006808)2.04437368
77Facial hemangioma (HP:0000329)2.02850401
78Abnormality of DNA repair (HP:0003254)2.02060890
79Abnormality of pyrimidine metabolism (HP:0004353)2.01083008
80Microretrognathia (HP:0000308)2.00014527
81Trismus (HP:0000211)1.99543427
82Acute lymphatic leukemia (HP:0006721)1.99379669
83Aplasia/Hypoplasia of the sacrum (HP:0008517)1.99334487
84Duplicated collecting system (HP:0000081)1.99268573
85Reduced antithrombin III activity (HP:0001976)1.98408946
86Squamous cell carcinoma (HP:0002860)1.97459282
87Testicular atrophy (HP:0000029)1.96418133
88Short thumb (HP:0009778)1.96251601
89Multiple enchondromatosis (HP:0005701)1.96014247
90Lymphoma (HP:0002665)1.95108364
91Rough bone trabeculation (HP:0100670)1.93412493
92Amaurosis fugax (HP:0100576)1.92958842
93Entropion (HP:0000621)1.92475851
94Impulsivity (HP:0100710)1.92052339
95Cutaneous melanoma (HP:0012056)1.91872301
96Renal duplication (HP:0000075)1.91865953
97Horseshoe kidney (HP:0000085)1.91369496
98Generalized amyotrophy (HP:0003700)1.91214166
99Absent radius (HP:0003974)1.90876076
100Abnormality of the fingertips (HP:0001211)1.90422945
101Hypergonadotropic hypogonadism (HP:0000815)1.88775745
102Reduced subcutaneous adipose tissue (HP:0003758)1.87761115
103Acute myeloid leukemia (HP:0004808)1.87233991
104Abnormality of the renal collecting system (HP:0004742)1.87144892
105High anterior hairline (HP:0009890)1.86058639
106External ear malformation (HP:0008572)1.85466198
107Cellular immunodeficiency (HP:0005374)1.84593796
108Abnormality of glycolysis (HP:0004366)1.83899559
109Short middle phalanx of the 5th finger (HP:0004220)1.82633776
110Abnormality of reticulocytes (HP:0004312)1.82266817
111Optic nerve coloboma (HP:0000588)1.81881537
112Hypertensive crisis (HP:0100735)1.81747224
113Abnormality of the calcaneus (HP:0008364)1.81099798
114IgM deficiency (HP:0002850)1.80725539
115Neoplasm of the colon (HP:0100273)1.80421408
116Abnormality of the fetal cardiovascular system (HP:0010948)1.79433262
117Abnormal umbilical cord blood vessels (HP:0011403)1.79433262
118Single umbilical artery (HP:0001195)1.79433262
119Reticulocytosis (HP:0001923)1.78660050
120Carpal bone hypoplasia (HP:0001498)1.76488740
121Pulmonary fibrosis (HP:0002206)1.76004397
122Ureteral stenosis (HP:0000071)1.75979355
123Pancytopenia (HP:0001876)1.75950874
124Aplasia involving forearm bones (HP:0009822)1.75507265
125Absent forearm bone (HP:0003953)1.75507265
126Poikiloderma (HP:0001029)1.75288932
127Pendular nystagmus (HP:0012043)1.74984814
128Abnormality of the prostate (HP:0008775)1.74693683
129B lymphocytopenia (HP:0010976)1.74675761
130Abnormality of B cell number (HP:0010975)1.74675761
131Abnormality of fatty-acid metabolism (HP:0004359)1.74345034
132Hyperacusis (HP:0010780)1.72576094
133Abnormality of cochlea (HP:0000375)1.71408981
134Long eyelashes (HP:0000527)1.70511979
135Abnormality of the columella (HP:0009929)1.69918061
136Cortical dysplasia (HP:0002539)1.69728434
137Truncus arteriosus (HP:0001660)1.68041769
138Secondary amenorrhea (HP:0000869)1.67401445
139Rhabdomyolysis (HP:0003201)1.66801859
140Abnormal foot bone ossification (HP:0010675)1.65396118
141Fatigue (HP:0012378)1.64821070
142Ulnar bowing (HP:0003031)1.64585858
143Nonimmune hydrops fetalis (HP:0001790)1.64555742
144Self-mutilation (HP:0000742)1.64406976
145Premature ovarian failure (HP:0008209)1.64219235
146Duplication of thumb phalanx (HP:0009942)1.63088061
147Abnormal gallbladder morphology (HP:0012437)1.62956325
148Petechiae (HP:0000967)1.62217923
149Overlapping toe (HP:0001845)1.61466606
150Abnormality of the gallbladder (HP:0005264)1.61422156

Predicted kinase interactions (KEA)

RankGene SetZ-score
1CDC75.12400523
2BUB14.16416988
3WEE13.84947592
4SMG13.43568700
5NEK23.13577883
6VRK23.04402073
7EIF2AK12.96752683
8TAOK22.92425821
9SRPK12.40628616
10ACVR1B2.31556262
11BRSK22.30917772
12TLK12.30761431
13EEF2K2.26211669
14TTK2.19674910
15PLK12.04300915
16PASK1.97925219
17PLK41.94824067
18MAP3K101.90803395
19TAOK11.89544849
20TSSK61.89426318
21MKNK11.88347169
22IRAK31.87683844
23CCNB11.84536058
24NEK11.82050014
25PBK1.81517374
26ATR1.81289159
27AURKB1.77915496
28NME21.76427802
29VRK11.72942116
30CDK71.69086445
31STK101.63874222
32BRSK11.61206410
33TESK21.53492122
34PRPF4B1.48883426
35CDK41.48283910
36RPS6KA41.47353254
37CHEK21.46295049
38MAP4K11.44696593
39ICK1.44446361
40CDK121.40684444
41MAP3K31.40519696
42PLK31.38838841
43STK161.38771720
44TGFBR11.37543514
45EIF2AK31.33926196
46TAF11.33166254
47RPS6KB21.32052131
48DYRK31.31026684
49MKNK21.29617871
50SCYL21.28833421
51MAP3K81.28034127
52CLK11.23046419
53CHEK11.22154138
54STK41.19671613
55CDK81.16519530
56PKN21.03334726
57AURKA1.02975981
58PAK41.01422025
59ATM0.95423342
60FLT30.90811889
61CDK20.89518363
62MARK30.88407954
63BTK0.86703779
64LRRK20.80066413
65CDK60.76497856
66PIM10.75439885
67BRD40.73227238
68ERN10.72804674
69EIF2AK20.71304754
70CDK10.70999015
71BLK0.70138775
72ARAF0.65302519
73PDK20.63707125
74TEC0.63519475
75MST1R0.63087503
76BMX0.59906917
77MAP2K30.59900762
78DAPK10.59288391
79CSNK2A10.58688355
80SIK10.57902401
81MELK0.57722222
82ZAP700.57665664
83PAK10.56723924
84KIT0.56548491
85CSNK2A20.56241242
86MAP3K10.56076413
87NME10.55358762
88CSF1R0.55258665
89STK30.54841651
90GRK60.53584645
91ABL20.53388619
92ILK0.52538163
93ZAK0.51901216
94MTOR0.51665024
95ALK0.51392059
96IRAK20.50798980
97PIM20.47122514
98NUAK10.46708436
99EPHA20.46201173
100MAP3K110.46168147
101BCKDK0.45152616
102NEK90.41295884
103ERBB40.35825388
104MAP2K20.35301545
105RAF10.34962434
106PRKDC0.34866189
107TESK10.34008305
108MAPKAPK50.33885344
109UHMK10.33626618
110AKT20.33334189
111TRIB30.32420528
112RPS6KA50.32276609
113BRAF0.32217707
114LYN0.31002895
115JAK30.30995497
116SYK0.30350018
117MAPK110.30036615
118RPS6KC10.29908031
119RPS6KL10.29908031
120CSNK1G30.29472449
121YES10.29410242
122RPS6KA60.27275693
123CDK11A0.26419633
124IRAK40.26108087
125MAPK140.25495456
126RPS6KB10.24769651
127KDR0.24111370
128CDK90.23831127
129CDK150.23414216
130MAPKAPK20.22690260

Predicted pathways (KEGG)

RankGene SetZ-score
1DNA replication_Homo sapiens_hsa030305.63775193
2Mismatch repair_Homo sapiens_hsa034304.57583537
3Base excision repair_Homo sapiens_hsa034103.56111481
4Homologous recombination_Homo sapiens_hsa034403.40452780
5Spliceosome_Homo sapiens_hsa030403.23228202
6Cell cycle_Homo sapiens_hsa041103.11488964
7Ribosome_Homo sapiens_hsa030103.07671414
8Nucleotide excision repair_Homo sapiens_hsa034202.96424966
9Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030082.90988854
10RNA transport_Homo sapiens_hsa030132.80948397
11One carbon pool by folate_Homo sapiens_hsa006702.59759568
12Fanconi anemia pathway_Homo sapiens_hsa034602.54891665
13RNA polymerase_Homo sapiens_hsa030202.38176878
14Proteasome_Homo sapiens_hsa030502.17809512
15Pyrimidine metabolism_Homo sapiens_hsa002402.14691596
16Non-homologous end-joining_Homo sapiens_hsa034502.12529510
17Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009701.96721840
18RNA degradation_Homo sapiens_hsa030181.96014787
19mRNA surveillance pathway_Homo sapiens_hsa030151.90313757
20Basal transcription factors_Homo sapiens_hsa030221.76143636
21p53 signaling pathway_Homo sapiens_hsa041151.56603048
22Citrate cycle (TCA cycle)_Homo sapiens_hsa000201.51119947
23Carbon metabolism_Homo sapiens_hsa012001.29028498
242-Oxocarboxylic acid metabolism_Homo sapiens_hsa012101.27646037
25Systemic lupus erythematosus_Homo sapiens_hsa053221.27606397
26Fatty acid elongation_Homo sapiens_hsa000621.20992571
27Epstein-Barr virus infection_Homo sapiens_hsa051691.14697183
28Oocyte meiosis_Homo sapiens_hsa041141.13884098
29Viral carcinogenesis_Homo sapiens_hsa052031.13808482
30Purine metabolism_Homo sapiens_hsa002301.11420969
31Progesterone-mediated oocyte maturation_Homo sapiens_hsa049141.09102504
32Herpes simplex infection_Homo sapiens_hsa051681.08832680
33Fructose and mannose metabolism_Homo sapiens_hsa000511.01479575
34Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.99662962
35Primary immunodeficiency_Homo sapiens_hsa053400.98437605
36HTLV-I infection_Homo sapiens_hsa051660.96840254
37Cytosolic DNA-sensing pathway_Homo sapiens_hsa046230.96257562
38Antigen processing and presentation_Homo sapiens_hsa046120.94079292
39Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.92933212
40Thyroid cancer_Homo sapiens_hsa052160.87480745
41Pyruvate metabolism_Homo sapiens_hsa006200.86413379
42Galactose metabolism_Homo sapiens_hsa000520.84926789
43Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004000.80031160
44Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.78392820
45MicroRNAs in cancer_Homo sapiens_hsa052060.77848788
46Transcriptional misregulation in cancer_Homo sapiens_hsa052020.76297260
47Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006300.75593177
48Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.74735600
49Small cell lung cancer_Homo sapiens_hsa052220.74635567
50SNARE interactions in vesicular transport_Homo sapiens_hsa041300.74192465
51Other glycan degradation_Homo sapiens_hsa005110.73787169
52Chronic myeloid leukemia_Homo sapiens_hsa052200.72767629
53N-Glycan biosynthesis_Homo sapiens_hsa005100.71384512
54* Lysine degradation_Homo sapiens_hsa003100.70236306
55Pentose phosphate pathway_Homo sapiens_hsa000300.69065504
56Colorectal cancer_Homo sapiens_hsa052100.68974094
57Hepatitis B_Homo sapiens_hsa051610.65766296
58Measles_Homo sapiens_hsa051620.63814539
59Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010400.63309248
60Alcoholism_Homo sapiens_hsa050340.62202548
61Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.61557970
62Protein export_Homo sapiens_hsa030600.59723884
63Apoptosis_Homo sapiens_hsa042100.59542763
64Glutathione metabolism_Homo sapiens_hsa004800.59150719
65Non-small cell lung cancer_Homo sapiens_hsa052230.51946352
66Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.51922360
67Biosynthesis of amino acids_Homo sapiens_hsa012300.51281426
68Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.50682313
69Legionellosis_Homo sapiens_hsa051340.50215518
70Shigellosis_Homo sapiens_hsa051310.50195065
71Basal cell carcinoma_Homo sapiens_hsa052170.49923006
72Cyanoamino acid metabolism_Homo sapiens_hsa004600.48980325
73Acute myeloid leukemia_Homo sapiens_hsa052210.46361186
74Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.45324134
75B cell receptor signaling pathway_Homo sapiens_hsa046620.43480835
76Pancreatic cancer_Homo sapiens_hsa052120.43198621
77Notch signaling pathway_Homo sapiens_hsa043300.42408825
78Viral myocarditis_Homo sapiens_hsa054160.42311179
79Hematopoietic cell lineage_Homo sapiens_hsa046400.41475192
80NF-kappa B signaling pathway_Homo sapiens_hsa040640.41382676
81Fc epsilon RI signaling pathway_Homo sapiens_hsa046640.41324765
82Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046500.40721946
83Bladder cancer_Homo sapiens_hsa052190.37852237
84Bacterial invasion of epithelial cells_Homo sapiens_hsa051000.37386892
85Influenza A_Homo sapiens_hsa051640.37294883
86Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046660.36855130
87Melanoma_Homo sapiens_hsa052180.35624239
88Cysteine and methionine metabolism_Homo sapiens_hsa002700.35594176
89Hippo signaling pathway_Homo sapiens_hsa043900.34739042
90Intestinal immune network for IgA production_Homo sapiens_hsa046720.34509268
91Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.33202714
92Vitamin B6 metabolism_Homo sapiens_hsa007500.32935966
93TGF-beta signaling pathway_Homo sapiens_hsa043500.32726072
94Pathways in cancer_Homo sapiens_hsa052000.32690858
95Central carbon metabolism in cancer_Homo sapiens_hsa052300.32448294
96Selenocompound metabolism_Homo sapiens_hsa004500.32020152
97Folate biosynthesis_Homo sapiens_hsa007900.31906016
98Drug metabolism - other enzymes_Homo sapiens_hsa009830.30176512
99Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.29139691
100Endometrial cancer_Homo sapiens_hsa052130.29087000
101HIF-1 signaling pathway_Homo sapiens_hsa040660.28066172
102Metabolic pathways_Homo sapiens_hsa011000.27577196
103Prostate cancer_Homo sapiens_hsa052150.27572248
104Leishmaniasis_Homo sapiens_hsa051400.26771766
105T cell receptor signaling pathway_Homo sapiens_hsa046600.26615864
106Sulfur relay system_Homo sapiens_hsa041220.26176993
107AMPK signaling pathway_Homo sapiens_hsa041520.25996683
108Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.25696294
109Glioma_Homo sapiens_hsa052140.25479799
110Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.23696202
111Fatty acid metabolism_Homo sapiens_hsa012120.23189485
112Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.22355312
113Jak-STAT signaling pathway_Homo sapiens_hsa046300.21839926
114mTOR signaling pathway_Homo sapiens_hsa041500.21545091
115Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.21473852
116Hedgehog signaling pathway_Homo sapiens_hsa043400.21443639
117Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005320.21225402
118Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001300.20678244
119RIG-I-like receptor signaling pathway_Homo sapiens_hsa046220.19944569
120Butirosin and neomycin biosynthesis_Homo sapiens_hsa005240.19843197
121Steroid biosynthesis_Homo sapiens_hsa001000.19380034
122Wnt signaling pathway_Homo sapiens_hsa043100.19282898
123Neurotrophin signaling pathway_Homo sapiens_hsa047220.18940633
124Longevity regulating pathway - mammal_Homo sapiens_hsa042110.18638064
125Arginine and proline metabolism_Homo sapiens_hsa003300.17454462
126Asthma_Homo sapiens_hsa053100.16704591
127NOD-like receptor signaling pathway_Homo sapiens_hsa046210.16509091
128Huntingtons disease_Homo sapiens_hsa050160.16498608
129Leukocyte transendothelial migration_Homo sapiens_hsa046700.15477462
130FoxO signaling pathway_Homo sapiens_hsa040680.14939346
131Platelet activation_Homo sapiens_hsa046110.14908158

Most similar genes based on co-expression Upload to Enrichr

Tissue Expression Export image »

Cell Line Expression Export image »