SUCLG2P4

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1protein K11-linked deubiquitination (GO:0035871)6.92174032
2detection of mechanical stimulus involved in sensory perception of sound (GO:0050910)5.15720979
3tryptophan catabolic process (GO:0006569)4.36440177
4indole-containing compound catabolic process (GO:0042436)4.36440177
5indolalkylamine catabolic process (GO:0046218)4.36440177
6indolalkylamine metabolic process (GO:0006586)4.29339727
7neural tube formation (GO:0001841)4.26665566
8reflex (GO:0060004)4.10184819
9protein K63-linked deubiquitination (GO:0070536)4.05939108
10serotonin receptor signaling pathway (GO:0007210)4.01330262
11photoreceptor cell maintenance (GO:0045494)3.98347621
12signal peptide processing (GO:0006465)3.90895702
13tryptophan metabolic process (GO:0006568)3.90833044
14DNA double-strand break processing (GO:0000729)3.89241835
15negative regulation of calcium ion transport into cytosol (GO:0010523)3.85625012
16tachykinin receptor signaling pathway (GO:0007217)3.80091138
17retinal cone cell development (GO:0046549)3.78789071
18auditory receptor cell stereocilium organization (GO:0060088)3.78319600
19cellular ketone body metabolic process (GO:0046950)3.77037831
20thyroid hormone metabolic process (GO:0042403)3.76263201
21righting reflex (GO:0060013)3.72055052
22detection of light stimulus involved in visual perception (GO:0050908)3.59800680
23detection of light stimulus involved in sensory perception (GO:0050962)3.59800680
24cilium or flagellum-dependent cell motility (GO:0001539)3.58493317
25response to pheromone (GO:0019236)3.56628458
26kynurenine metabolic process (GO:0070189)3.54791482
27sulfation (GO:0051923)3.54143248
28ketone body metabolic process (GO:1902224)3.46254061
29startle response (GO:0001964)3.42179296
30protein K48-linked deubiquitination (GO:0071108)3.37423286
31regulation of sarcomere organization (GO:0060297)3.30952419
32replication fork processing (GO:0031297)3.29235056
33piRNA metabolic process (GO:0034587)3.21017487
34detection of mechanical stimulus involved in sensory perception (GO:0050974)3.20829597
35inner ear receptor stereocilium organization (GO:0060122)3.19549698
36fucose catabolic process (GO:0019317)3.15075160
37L-fucose metabolic process (GO:0042354)3.15075160
38L-fucose catabolic process (GO:0042355)3.15075160
39behavioral response to nicotine (GO:0035095)3.14903626
40indole-containing compound metabolic process (GO:0042430)3.14109940
41negative regulation of calcium ion-dependent exocytosis (GO:0045955)3.11214145
42gamma-aminobutyric acid transport (GO:0015812)3.10258917
43regulation of hippo signaling (GO:0035330)3.09665053
44regulation of establishment of cell polarity (GO:2000114)3.07375778
45sex differentiation (GO:0007548)3.07239801
46lipid translocation (GO:0034204)2.98774402
47phospholipid translocation (GO:0045332)2.98774402
48regulation of collateral sprouting (GO:0048670)2.98563700
49negative regulation of mast cell activation (GO:0033004)2.98249506
50G-protein coupled glutamate receptor signaling pathway (GO:0007216)2.94312862
51positive regulation of oligodendrocyte differentiation (GO:0048714)2.94213213
52DNA methylation involved in gamete generation (GO:0043046)2.93168379
53amine catabolic process (GO:0009310)2.91086592
54cellular biogenic amine catabolic process (GO:0042402)2.91086592
55flavonoid metabolic process (GO:0009812)2.90606444
56establishment of protein localization to Golgi (GO:0072600)2.88359754
57regulation of meiosis I (GO:0060631)2.85525952
58positive regulation of vasculogenesis (GO:2001214)2.85110031
59L-methionine biosynthetic process from methylthioadenosine (GO:0019509)2.83792586
60dicarboxylic acid catabolic process (GO:0043649)2.83067104
61glycerophospholipid catabolic process (GO:0046475)2.82784428
62aromatic amino acid family catabolic process (GO:0009074)2.82514914
63killing of cells of other organism (GO:0031640)2.81547241
64disruption of cells of other organism (GO:0044364)2.81547241
65serotonin metabolic process (GO:0042428)2.79928162
66dopamine transport (GO:0015872)2.79907717
67cilium morphogenesis (GO:0060271)2.77718822
68nonmotile primary cilium assembly (GO:0035058)2.76699235
69behavioral response to ethanol (GO:0048149)2.74018597
70sphingoid metabolic process (GO:0046519)2.73408219
71recombinational repair (GO:0000725)2.72453906
72cellular response to sterol (GO:0036315)2.72424667
73activated T cell proliferation (GO:0050798)2.71962009
74synapsis (GO:0007129)2.70612814
75double-strand break repair via homologous recombination (GO:0000724)2.69135238
76regulation of appetite (GO:0032098)2.69022166
77NAD biosynthetic process (GO:0009435)2.67984246
78regulation of action potential (GO:0098900)2.67841700
79photoreceptor cell development (GO:0042461)2.67202869
80axoneme assembly (GO:0035082)2.66201140
81regulation of establishment or maintenance of cell polarity (GO:0032878)2.64637830
82monoubiquitinated protein deubiquitination (GO:0035520)2.64246743
83adaptation of signaling pathway (GO:0023058)2.63557291
84aspartate family amino acid catabolic process (GO:0009068)2.63542555
85aromatic amino acid family metabolic process (GO:0009072)2.60537083
86primary amino compound metabolic process (GO:1901160)2.59973883
87benzene-containing compound metabolic process (GO:0042537)2.59675040
88interferon-gamma production (GO:0032609)2.58742336
89prenylation (GO:0097354)2.58436557
90protein prenylation (GO:0018342)2.58436557
91positive regulation of inositol phosphate biosynthetic process (GO:0060732)2.58076875
92peptidyl-histidine modification (GO:0018202)2.58018050
93proline transport (GO:0015824)2.56826731
94cilium organization (GO:0044782)2.55491273
95thyroid hormone generation (GO:0006590)2.53390700
96protein K6-linked ubiquitination (GO:0085020)2.52602988
97cilium assembly (GO:0042384)2.52279948
98negative regulation of cytosolic calcium ion concentration (GO:0051481)2.50091978
99regulation of short-term neuronal synaptic plasticity (GO:0048172)2.49622889
100regulation of hexokinase activity (GO:1903299)2.49277695

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1GBX2_23144817_ChIP-Seq_PC3_Human4.03970887
2IGF1R_20145208_ChIP-Seq_DFB_Human3.39865848
3VDR_22108803_ChIP-Seq_LS180_Human3.10601283
4ZNF274_21170338_ChIP-Seq_K562_Hela3.00046439
5GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse2.91135084
6TAF15_26573619_Chip-Seq_HEK293_Human2.81555498
7ZFP57_27257070_Chip-Seq_ESCs_Mouse2.79146609
8POU3F2_20337985_ChIP-ChIP_501MEL_Human2.76268070
9GLI1_17442700_ChIP-ChIP_MESCs_Mouse2.53563599
10CTBP2_25329375_ChIP-Seq_LNCAP_Human2.49834668
11CEBPD_23245923_ChIP-Seq_MEFs_Mouse2.43016182
12P300_19829295_ChIP-Seq_ESCs_Human2.28021352
13ER_23166858_ChIP-Seq_MCF-7_Human2.21768031
14FLI1_27457419_Chip-Seq_LIVER_Mouse2.15375452
15EWS_26573619_Chip-Seq_HEK293_Human2.12479102
16SMARCD1_25818293_ChIP-Seq_ESCs_Mouse2.08322384
17AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human2.05821873
18FUS_26573619_Chip-Seq_HEK293_Human2.05297751
19CTBP1_25329375_ChIP-Seq_LNCAP_Human2.04891500
20SALL1_21062744_ChIP-ChIP_HESCs_Human1.95394804
21SMAD4_21799915_ChIP-Seq_A2780_Human1.91243033
22STAT3_23295773_ChIP-Seq_U87_Human1.88768707
23UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human1.80916739
24BCAT_22108803_ChIP-Seq_LS180_Human1.80572119
25HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse1.76301685
26EZH2_22144423_ChIP-Seq_EOC_Human1.76255885
27PIAS1_25552417_ChIP-Seq_VCAP_Human1.73541175
28BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse1.71959566
29TCF4_23295773_ChIP-Seq_U87_Human1.71659350
30PCGF2_27294783_Chip-Seq_ESCs_Mouse1.71222643
31AR_25329375_ChIP-Seq_VCAP_Human1.70848012
32IRF4_20064451_ChIP-Seq_CD4+T_Mouse1.68485517
33CBP_20019798_ChIP-Seq_JUKART_Human1.68485517
34AR_21572438_ChIP-Seq_LNCaP_Human1.63816237
35SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.63130959
36PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.58211000
37NR3C1_21868756_ChIP-Seq_MCF10A_Human1.55413314
38MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse1.53237848
39SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.51764400
40EZH2_27294783_Chip-Seq_NPCs_Mouse1.50359538
41SMAD3_21741376_ChIP-Seq_EPCs_Human1.47462133
42TCF4_22108803_ChIP-Seq_LS180_Human1.46863828
43SMAD_19615063_ChIP-ChIP_OVARY_Human1.43445270
44KLF5_20875108_ChIP-Seq_MESCs_Mouse1.43065268
45PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse1.39895513
46RUNX2_22187159_ChIP-Seq_PCA_Human1.38299518
47OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.37425784
48FLI1_21867929_ChIP-Seq_TH2_Mouse1.36274430
49TOP2B_26459242_ChIP-Seq_MCF-7_Human1.35150593
50TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.34865375
51CDX2_21402776_ChIP-Seq_INTESTINAL-VILLUS_Mouse1.34790141
52SUZ12_27294783_Chip-Seq_NPCs_Mouse1.34307842
53SMAD4_21741376_ChIP-Seq_EPCs_Human1.33002546
54FOXA1_21572438_ChIP-Seq_LNCaP_Human1.32172377
55TP53_22573176_ChIP-Seq_HFKS_Human1.31525259
56NFE2_27457419_Chip-Seq_LIVER_Mouse1.30800867
57EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human1.30684882
58MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human1.30060820
59EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human1.29629251
60CRX_20693478_ChIP-Seq_RETINA_Mouse1.28705029
61MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.27464392
62CDX2_22108803_ChIP-Seq_LS180_Human1.25853389
63NANOG_18555785_Chip-Seq_ESCs_Mouse1.25484568
64ZFP322A_24550733_ChIP-Seq_MESCs_Mouse1.24593159
65TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse1.24395418
66PRDM14_20953172_ChIP-Seq_ESCs_Human1.22939008
67SOX2_19829295_ChIP-Seq_ESCs_Human1.22186386
68NANOG_19829295_ChIP-Seq_ESCs_Human1.22186386
69OCT4_21477851_ChIP-Seq_ESCs_Mouse1.20237447
70TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.20143915
71POU5F1_26923725_Chip-Seq_MESODERM_Mouse1.20143915
72RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.18680482
73TP53_16413492_ChIP-PET_HCT116_Human1.16817234
74TEAD4_22529382_ChIP-Seq_TROPHECTODERM_Mouse1.16435439
75NOTCH1_21737748_ChIP-Seq_TLL_Human1.14634207
76TAL1_21186366_ChIP-Seq_BM-HSCs_Mouse1.11839341
77PCGF2_27294783_Chip-Seq_NPCs_Mouse1.11686876
78EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse1.11483506
79FOXA1_25329375_ChIP-Seq_VCAP_Human1.11290411
80FOXA1_27270436_Chip-Seq_PROSTATE_Human1.11290411
81CBX2_27304074_Chip-Seq_ESCs_Mouse1.10390535
82DROSHA_22980978_ChIP-Seq_HELA_Human1.09684125
83CDX2_19796622_ChIP-Seq_MESCs_Mouse1.08255647
84P53_22387025_ChIP-Seq_ESCs_Mouse1.06965290
85TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human1.06869396
86SOX6_21985497_ChIP-Seq_MYOTUBES_Mouse1.06556590
87HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human1.06479946
88REST_21632747_ChIP-Seq_MESCs_Mouse1.05849468
89TAL1_26923725_Chip-Seq_HPCs_Mouse1.05593923
90IRF1_19129219_ChIP-ChIP_H3396_Human1.03524146
91E2F1_18555785_Chip-Seq_ESCs_Mouse1.03029512
92RNF2_27304074_Chip-Seq_NSC_Mouse1.02941948
93JUN_21703547_ChIP-Seq_K562_Human1.01464996
94NCOR_22424771_ChIP-Seq_293T_Human1.00354841
95FOXM1_26456572_ChIP-Seq_MCF-7_Human1.00157547
96ARNT_22903824_ChIP-Seq_MCF-7_Human0.99567691
97EGR1_23403033_ChIP-Seq_LIVER_Mouse0.99078128
98TBL1_22424771_ChIP-Seq_293T_Human0.99024417
99STAT3_18555785_Chip-Seq_ESCs_Mouse0.97257917
100KLF4_25985364_ChIP-Seq_ATHEROSCLEROSIS_LESION_Mouse0.97044867

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0000569_abnormal_digit_pigmentation3.77172321
2MP0003195_calcinosis3.30440774
3MP0008057_abnormal_DNA_replication3.00407180
4MP0005551_abnormal_eye_electrophysiolog2.64374717
5MP0002837_dystrophic_cardiac_calcinosis2.56696744
6MP0002736_abnormal_nociception_after2.49368205
7MP0008877_abnormal_DNA_methylation2.48888244
8MP0001968_abnormal_touch/_nociception2.47902876
9MP0002102_abnormal_ear_morphology2.42829884
10MP0009046_muscle_twitch2.32913403
11MP0004043_abnormal_pH_regulation2.23332529
12MP0002138_abnormal_hepatobiliary_system2.22890351
13MP0003183_abnormal_peptide_metabolism2.16899686
14MP0000372_irregular_coat_pigmentation2.16375205
15MP0001501_abnormal_sleep_pattern2.15366168
16MP0003646_muscle_fatigue2.06873720
17MP0005171_absent_coat_pigmentation2.04721919
18MP0006276_abnormal_autonomic_nervous1.97875603
19MP0000427_abnormal_hair_cycle1.96214797
20MP0005253_abnormal_eye_physiology1.94976426
21MP0005670_abnormal_white_adipose1.93003454
22MP0005310_abnormal_salivary_gland1.92840575
23MP0001984_abnormal_olfaction1.92056158
24MP0005646_abnormal_pituitary_gland1.90640814
25MP0009745_abnormal_behavioral_response1.89133235
26MP0001486_abnormal_startle_reflex1.84257241
27MP0003880_abnormal_central_pattern1.78388427
28MP0004147_increased_porphyrin_level1.71916898
29MP0003136_yellow_coat_color1.68373574
30MP0002272_abnormal_nervous_system1.62953607
31MP0002938_white_spotting1.58566308
32MP0002876_abnormal_thyroid_physiology1.56488247
33MP0002234_abnormal_pharynx_morphology1.55881098
34MP0003787_abnormal_imprinting1.47626160
35MP0005174_abnormal_tail_pigmentation1.46760895
36MP0001986_abnormal_taste_sensitivity1.46586699
37MP0006292_abnormal_olfactory_placode1.46361890
38MP0002064_seizures1.39484152
39MP0000383_abnormal_hair_follicle1.36935847
40MP0010386_abnormal_urinary_bladder1.36837056
41MP0008872_abnormal_physiological_respon1.34860052
42MP0008875_abnormal_xenobiotic_pharmacok1.31590601
43MP0002163_abnormal_gland_morphology1.31312226
44MP0005647_abnormal_sex_gland1.31081130
45MP0001970_abnormal_pain_threshold1.28740590
46MP0002254_reproductive_system_inflammat1.26079673
47MP0000631_abnormal_neuroendocrine_gland1.23428669
48MP0006072_abnormal_retinal_apoptosis1.21510609
49MP0002735_abnormal_chemical_nociception1.21340926
50MP0003252_abnormal_bile_duct1.19990049
51MP0001485_abnormal_pinna_reflex1.17871647
52MP0002572_abnormal_emotion/affect_behav1.16407256
53MP0004924_abnormal_behavior1.14109046
54MP0005386_behavior/neurological_phenoty1.14109046
55MP0003718_maternal_effect1.11358477
56MP0001764_abnormal_homeostasis1.11131729
57MP0005645_abnormal_hypothalamus_physiol1.08307118
58MP0000371_diluted_coat_color1.07301305
59MP0002095_abnormal_skin_pigmentation1.05612799
60MP0004142_abnormal_muscle_tone1.05473215
61MP0008058_abnormal_DNA_repair1.05284594
62MP0002733_abnormal_thermal_nociception1.04275305
63MP0005085_abnormal_gallbladder_physiolo1.04168130
64MP0002653_abnormal_ependyma_morphology1.02310215
65MP0005075_abnormal_melanosome_morpholog1.01745689
66MP0002067_abnormal_sensory_capabilities1.01100955
67MP0005379_endocrine/exocrine_gland_phen0.99409354
68MP0009697_abnormal_copulation0.98760904
69MP0005084_abnormal_gallbladder_morpholo0.98667666
70MP0004215_abnormal_myocardial_fiber0.94104376
71MP0002229_neurodegeneration0.93145713
72MP0005389_reproductive_system_phenotype0.92967113
73MP0003635_abnormal_synaptic_transmissio0.91538602
74MP0003698_abnormal_male_reproductive0.90646540
75MP0001529_abnormal_vocalization0.88864846
76MP0002928_abnormal_bile_duct0.88581539
77MP0002090_abnormal_vision0.88324768
78MP0002638_abnormal_pupillary_reflex0.88265928
79MP0005410_abnormal_fertilization0.87194725
80MP0000230_abnormal_systemic_arterial0.85300198
81MP0002557_abnormal_social/conspecific_i0.85123957
82MP0001919_abnormal_reproductive_system0.83915834
83MP0000015_abnormal_ear_pigmentation0.82957365
84MP0003045_fibrosis0.82378007
85MP0002139_abnormal_hepatobiliary_system0.82176835
86MP0002751_abnormal_autonomic_nervous0.81783806
87MP0002063_abnormal_learning/memory/cond0.81254925
88MP0005408_hypopigmentation0.80950505
89MP0004742_abnormal_vestibular_system0.80823838
90MP0003806_abnormal_nucleotide_metabolis0.80454011
91MP0005266_abnormal_metabolism0.80075202
92MP0001324_abnormal_eye_pigmentation0.79998768
93MP0005195_abnormal_posterior_eye0.78967460
94MP0005167_abnormal_blood-brain_barrier0.77612681
95MP0003137_abnormal_impulse_conducting0.75991803
96MP0001929_abnormal_gametogenesis0.73849275
97MP0001963_abnormal_hearing_physiology0.73320281
98MP0002734_abnormal_mechanical_nocicepti0.73090211
99MP0002752_abnormal_somatic_nervous0.73049442
100MP0005395_other_phenotype0.72331216

Predicted human phenotypes

RankGene SetZ-score
1Hyperventilation (HP:0002883)4.75035616
2Pancreatic cysts (HP:0001737)4.71146091
3True hermaphroditism (HP:0010459)4.24825445
4Pancreatic fibrosis (HP:0100732)4.20020301
5Congenital stationary night blindness (HP:0007642)3.80836435
6Gaze-evoked nystagmus (HP:0000640)3.75405782
7Attenuation of retinal blood vessels (HP:0007843)3.72125231
8Abnormality of midbrain morphology (HP:0002418)3.45627756
9Molar tooth sign on MRI (HP:0002419)3.45627756
10Absent speech (HP:0001344)3.35961091
11Congenital sensorineural hearing impairment (HP:0008527)3.32716598
12Genetic anticipation (HP:0003743)3.28181347
13Chronic hepatic failure (HP:0100626)3.25382848
14Progressive cerebellar ataxia (HP:0002073)3.17789542
15Abolished electroretinogram (ERG) (HP:0000550)3.11301978
16Nephronophthisis (HP:0000090)3.10592807
17Cystic liver disease (HP:0006706)2.93633193
18Bony spicule pigmentary retinopathy (HP:0007737)2.92030397
19Abnormality of the renal medulla (HP:0100957)2.89398438
20Abnormality of the renal cortex (HP:0011035)2.88984338
21Aplasia/Hypoplasia of the tibia (HP:0005772)2.82645591
22Medial flaring of the eyebrow (HP:0010747)2.77712426
23Intestinal atresia (HP:0011100)2.71002647
24Aplasia/Hypoplasia of the tongue (HP:0010295)2.66627420
25Decreased central vision (HP:0007663)2.64374580
26Pendular nystagmus (HP:0012043)2.45878368
27Fair hair (HP:0002286)2.43282067
28Febrile seizures (HP:0002373)2.42809588
29Absent rod-and cone-mediated responses on ERG (HP:0007688)2.41957759
30Cerebellar dysplasia (HP:0007033)2.40035574
31Sclerocornea (HP:0000647)2.34552357
32Focal motor seizures (HP:0011153)2.30315185
33Gait imbalance (HP:0002141)2.29582796
34Clumsiness (HP:0002312)2.28972047
35Congenital primary aphakia (HP:0007707)2.28267902
36Male pseudohermaphroditism (HP:0000037)2.28135404
37Large for gestational age (HP:0001520)2.27348683
38Abnormal drinking behavior (HP:0030082)2.27020422
39Polydipsia (HP:0001959)2.27020422
40Protruding tongue (HP:0010808)2.26469408
41Congenital hepatic fibrosis (HP:0002612)2.25505702
42Focal seizures (HP:0007359)2.18423083
43Genital tract atresia (HP:0001827)2.18346324
44Decreased electroretinogram (ERG) amplitude (HP:0000654)2.18234080
45Type II lissencephaly (HP:0007260)2.17869267
46Progressive inability to walk (HP:0002505)2.14253264
47Furrowed tongue (HP:0000221)2.14036695
48Abnormal rod and cone electroretinograms (HP:0008323)2.13977984
49Postaxial foot polydactyly (HP:0001830)2.12302589
50Widely spaced teeth (HP:0000687)2.12039128
51Dialeptic seizures (HP:0011146)2.11648737
52Retinitis pigmentosa (HP:0000510)2.10999235
53Anencephaly (HP:0002323)2.08513499
54Keratoconus (HP:0000563)2.07659618
55Increased corneal curvature (HP:0100692)2.07659618
56Bile duct proliferation (HP:0001408)2.06216385
57Abnormal biliary tract physiology (HP:0012439)2.06216385
58Ketoacidosis (HP:0001993)2.04875569
59Decreased circulating renin level (HP:0003351)2.01130228
60Inability to walk (HP:0002540)2.00364077
61Astigmatism (HP:0000483)2.00069978
62Hyperglycinuria (HP:0003108)1.99472297
63Vaginal atresia (HP:0000148)1.99216218
64Nephrogenic diabetes insipidus (HP:0009806)1.98871163
65Small hand (HP:0200055)1.98110887
66Generalized hypopigmentation of hair (HP:0011358)1.97012025
67Broad-based gait (HP:0002136)1.92145029
68Constricted visual fields (HP:0001133)1.91930351
69Aplasia/Hypoplasia of the uvula (HP:0010293)1.91156143
70Abnormality of alanine metabolism (HP:0010916)1.89799038
71Hyperalaninemia (HP:0003348)1.89799038
72Abnormality of pyruvate family amino acid metabolism (HP:0010915)1.89799038
73Amelogenesis imperfecta (HP:0000705)1.89531257
74Methylmalonic aciduria (HP:0012120)1.89429338
75Tubular atrophy (HP:0000092)1.88845305
76Tented upper lip vermilion (HP:0010804)1.87310462
77Preaxial hand polydactyly (HP:0001177)1.87049678
78Drooling (HP:0002307)1.85711903
79Short foot (HP:0001773)1.85391801
80Occipital encephalocele (HP:0002085)1.85179917
81Abnormality of macular pigmentation (HP:0008002)1.83355851
82Polyuria (HP:0000103)1.83229793
83Volvulus (HP:0002580)1.83218406
84Central scotoma (HP:0000603)1.81317475
85Thyroid-stimulating hormone excess (HP:0002925)1.80964349
86Stomach cancer (HP:0012126)1.80752479
87Retinal dysplasia (HP:0007973)1.77833414
88Facial diplegia (HP:0001349)1.75929899
893-Methylglutaconic aciduria (HP:0003535)1.73101512
90Poikiloderma (HP:0001029)1.73062928
91Severe visual impairment (HP:0001141)1.72441456
92Optic nerve hypoplasia (HP:0000609)1.72044247
93Sloping forehead (HP:0000340)1.69818352
94Absent/shortened dynein arms (HP:0200106)1.68517471
95Dynein arm defect of respiratory motile cilia (HP:0012255)1.68517471
96Chorioretinal atrophy (HP:0000533)1.68395510
97Poor coordination (HP:0002370)1.68351283
98Ketosis (HP:0001946)1.67286561
99Delayed puberty (HP:0000823)1.66817738
100Dandy-Walker malformation (HP:0001305)1.64438841

Predicted kinase interactions (KEA)

RankGene SetZ-score
1FRK8.98265319
2WNK33.37215123
3ADRBK22.59027603
4MAP4K22.58942568
5BMPR1B2.37637036
6ACVR1B2.23401221
7PINK12.12715737
8MAPK132.07621495
9ZAK1.94187526
10TRIM281.91801223
11INSRR1.88758386
12BCR1.85953368
13CASK1.79195791
14GRK11.77293980
15STK38L1.77191931
16NTRK31.69797371
17FER1.59345429
18OXSR11.59319517
19NUAK11.42086274
20MAP3K41.40025242
21PRKD31.39592063
22MKNK21.35342182
23TXK1.30241342
24TAOK31.28513255
25LATS11.22489972
26MARK11.22009376
27ERBB31.16266991
28STK391.16208511
29STK31.09495528
30EIF2AK31.08050568
31PAK31.06262239
32EPHA41.00852745
33BRSK21.00535458
34PRKCE0.96677135
35ADRBK10.96365424
36PTK2B0.93204088
37TNIK0.87767284
38PDK20.87135837
39AKT30.82899514
40TEC0.79969549
41WNK40.75158585
42MKNK10.73553886
43CSNK1A1L0.73001719
44CSNK1G10.69570605
45PLK20.67698474
46MARK30.67275355
47PLK40.67205902
48TGFBR10.65078397
49CSNK1G30.64830141
50PIK3CA0.64757321
51IRAK10.64581874
52CSNK1G20.63995183
53YES10.63289584
54TNK20.63035865
55MST40.59233099
56PLK30.58505302
57PRKCG0.55764785
58DAPK20.54451949
59FGFR20.54076331
60MAP2K70.49936904
61PIK3CG0.49602586
62PRKCZ0.49201855
63DYRK20.47493555
64CAMK2A0.47341626
65GRK50.47256607
66WEE10.46337174
67PKN10.44021048
68SGK20.41875477
69PRKAA20.41443516
70MAPKAPK50.41270759
71STK380.40741144
72CSNK1A10.39638666
73CDK30.39240051
74TRPM70.39148869
75CSNK1D0.38662790
76CHEK20.38595143
77PRKACA0.37462190
78PRKG10.37440705
79TAF10.36943748
80MAPKAPK30.35667368
81EIF2AK20.35475937
82CDK190.35171207
83MAP3K70.34263016
84CCNB10.33676010
85PRKCH0.33292336
86CAMKK20.32199896
87DYRK30.32073841
88OBSCN0.31767434
89FLT30.30282609
90BCKDK0.29428163
91BLK0.29192521
92IKBKB0.28773521
93VRK10.28690687
94NEK60.28405796
95ATR0.27815275
96ATM0.26988231
97RPS6KA50.26449905
98PRKCB0.26282244
99GRK70.26135754
100ABL10.25774564

Predicted pathways (KEGG)

RankGene SetZ-score
1Butanoate metabolism_Homo sapiens_hsa006503.18714364
2Synthesis and degradation of ketone bodies_Homo sapiens_hsa000723.04845869
3Phototransduction_Homo sapiens_hsa047442.80068327
4Propanoate metabolism_Homo sapiens_hsa006402.61636708
5Primary bile acid biosynthesis_Homo sapiens_hsa001202.35887899
6Nicotine addiction_Homo sapiens_hsa050332.24064105
7Taurine and hypotaurine metabolism_Homo sapiens_hsa004302.16171166
8Neuroactive ligand-receptor interaction_Homo sapiens_hsa040802.15413872
9alpha-Linolenic acid metabolism_Homo sapiens_hsa005922.15032689
10Linoleic acid metabolism_Homo sapiens_hsa005912.12122311
11Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006012.09758276
12Nitrogen metabolism_Homo sapiens_hsa009102.05706674
13Tryptophan metabolism_Homo sapiens_hsa003802.05191192
14Valine, leucine and isoleucine degradation_Homo sapiens_hsa002802.04643200
15Ether lipid metabolism_Homo sapiens_hsa005651.91726213
16Selenocompound metabolism_Homo sapiens_hsa004501.90449220
17Non-homologous end-joining_Homo sapiens_hsa034501.87271655
18Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001301.79575271
19Homologous recombination_Homo sapiens_hsa034401.77282925
20ABC transporters_Homo sapiens_hsa020101.70254942
21Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005631.69921333
22Steroid hormone biosynthesis_Homo sapiens_hsa001401.67597563
23Fanconi anemia pathway_Homo sapiens_hsa034601.66060514
24Taste transduction_Homo sapiens_hsa047421.62884721
25Maturity onset diabetes of the young_Homo sapiens_hsa049501.53490551
26Olfactory transduction_Homo sapiens_hsa047401.48762604
27Terpenoid backbone biosynthesis_Homo sapiens_hsa009001.48482651
28Morphine addiction_Homo sapiens_hsa050321.40799843
29Glycerolipid metabolism_Homo sapiens_hsa005611.38377526
30Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006031.36470208
31Histidine metabolism_Homo sapiens_hsa003401.32847949
32Drug metabolism - cytochrome P450_Homo sapiens_hsa009821.29593587
33Ascorbate and aldarate metabolism_Homo sapiens_hsa000531.19037058
34Serotonergic synapse_Homo sapiens_hsa047261.17975235
35Retrograde endocannabinoid signaling_Homo sapiens_hsa047231.13600399
36Salivary secretion_Homo sapiens_hsa049701.13306571
37Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006041.12595592
38beta-Alanine metabolism_Homo sapiens_hsa004101.12525943
39GABAergic synapse_Homo sapiens_hsa047271.09454126
40RNA polymerase_Homo sapiens_hsa030201.08846207
41Peroxisome_Homo sapiens_hsa041461.08160465
42Dorso-ventral axis formation_Homo sapiens_hsa043201.07980663
43Fatty acid metabolism_Homo sapiens_hsa012121.07404405
44Calcium signaling pathway_Homo sapiens_hsa040201.07149990
45Fat digestion and absorption_Homo sapiens_hsa049751.06223280
46Arachidonic acid metabolism_Homo sapiens_hsa005901.05394631
47Retinol metabolism_Homo sapiens_hsa008301.05069295
48Fatty acid degradation_Homo sapiens_hsa000711.03804689
49Glycosaminoglycan degradation_Homo sapiens_hsa005311.01195316
50Chemical carcinogenesis_Homo sapiens_hsa052040.99859492
51Ovarian steroidogenesis_Homo sapiens_hsa049130.99576278
52Glutamatergic synapse_Homo sapiens_hsa047240.98655499
53N-Glycan biosynthesis_Homo sapiens_hsa005100.95728928
54Circadian entrainment_Homo sapiens_hsa047130.92602850
55Basal transcription factors_Homo sapiens_hsa030220.92044367
56Caffeine metabolism_Homo sapiens_hsa002320.88003751
57Insulin secretion_Homo sapiens_hsa049110.84868145
58Cysteine and methionine metabolism_Homo sapiens_hsa002700.84643715
59Lysine degradation_Homo sapiens_hsa003100.84636623
60Pancreatic secretion_Homo sapiens_hsa049720.80615529
61Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.76460065
62Protein export_Homo sapiens_hsa030600.74179704
63Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.73392207
64Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010400.73212172
65Sphingolipid metabolism_Homo sapiens_hsa006000.70707041
66Fatty acid elongation_Homo sapiens_hsa000620.68852504
67One carbon pool by folate_Homo sapiens_hsa006700.67985705
68Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.62460832
69Metabolic pathways_Homo sapiens_hsa011000.60573478
70Steroid biosynthesis_Homo sapiens_hsa001000.60301332
71cAMP signaling pathway_Homo sapiens_hsa040240.60014847
72RNA degradation_Homo sapiens_hsa030180.59806263
73Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.57714982
74Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.56011715
75Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.55749928
76Fatty acid biosynthesis_Homo sapiens_hsa000610.55621971
77Vascular smooth muscle contraction_Homo sapiens_hsa042700.54940024
78Collecting duct acid secretion_Homo sapiens_hsa049660.54108246
79Purine metabolism_Homo sapiens_hsa002300.53581793
80Cholinergic synapse_Homo sapiens_hsa047250.52477774
81Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.51120702
82Regulation of autophagy_Homo sapiens_hsa041400.49626583
83Dopaminergic synapse_Homo sapiens_hsa047280.48706851
84Pentose and glucuronate interconversions_Homo sapiens_hsa000400.47300322
85Glutathione metabolism_Homo sapiens_hsa004800.46309368
86Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.45129141
87Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006300.44996581
88Long-term depression_Homo sapiens_hsa047300.44335895
89Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.39942633
90Proteasome_Homo sapiens_hsa030500.39915103
91Vitamin digestion and absorption_Homo sapiens_hsa049770.39151330
92Glycerophospholipid metabolism_Homo sapiens_hsa005640.37759817
93Gastric acid secretion_Homo sapiens_hsa049710.35825084
94Circadian rhythm_Homo sapiens_hsa047100.30629772
95Cyanoamino acid metabolism_Homo sapiens_hsa004600.28733021
96Renin secretion_Homo sapiens_hsa049240.27464541
97Oxytocin signaling pathway_Homo sapiens_hsa049210.26775825
98Cocaine addiction_Homo sapiens_hsa050300.24745017
99Hedgehog signaling pathway_Homo sapiens_hsa043400.24491578
100Aldosterone synthesis and secretion_Homo sapiens_hsa049250.24288518

Most similar genes based on co-expression Upload to Enrichr

Tissue Expression Export image »

Cell Line Expression Export image »