STPG1

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1acrosome assembly (GO:0001675)9.83428285
2multicellular organism reproduction (GO:0032504)9.62339583
3motile cilium assembly (GO:0044458)9.60536754
4binding of sperm to zona pellucida (GO:0007339)9.28974232
5cilium movement (GO:0003341)9.21860770
6spermatid development (GO:0007286)9.21487183
7regulation of cilium movement (GO:0003352)9.12790452
8plasma membrane fusion (GO:0045026)9.07242202
9cell-cell recognition (GO:0009988)9.05565431
10reproduction (GO:0000003)8.18849649
11epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287)7.96962015
12piRNA metabolic process (GO:0034587)7.64286347
13male meiosis (GO:0007140)7.16043471
14synaptonemal complex organization (GO:0070193)7.05480946
15negative regulation of inclusion body assembly (GO:0090084)6.88321965
16single fertilization (GO:0007338)6.83328215
17synaptonemal complex assembly (GO:0007130)6.65992518
18sperm capacitation (GO:0048240)6.65777609
19spermatogenesis (GO:0007283)6.30853327
20male gamete generation (GO:0048232)6.28658461
21ventricular system development (GO:0021591)5.99773617
22fertilization (GO:0009566)5.95693805
23organic cation transport (GO:0015695)5.83802462
24gamete generation (GO:0007276)5.79843571
25microtubule depolymerization (GO:0007019)5.66765522
26regulation of inclusion body assembly (GO:0090083)5.62242614
27calcium ion-dependent exocytosis (GO:0017156)5.42292952
28microtubule severing (GO:0051013)5.39446339
29regulation of microtubule-based movement (GO:0060632)5.30926940
30germ cell development (GO:0007281)5.15184793
31DNA methylation involved in gamete generation (GO:0043046)5.06779459
32male meiosis I (GO:0007141)5.02591272
33cellular process involved in reproduction in multicellular organism (GO:0022412)4.98799046
34left/right pattern formation (GO:0060972)4.73291418
35response to pheromone (GO:0019236)4.69948273
36behavioral response to nicotine (GO:0035095)4.61291202
37multicellular organismal reproductive process (GO:0048609)4.59091995
38cell recognition (GO:0008037)4.45674099
39glycerol ether metabolic process (GO:0006662)4.42736512
40chromosome organization involved in meiosis (GO:0070192)4.36151436
41seminiferous tubule development (GO:0072520)4.29610864
42meiotic nuclear division (GO:0007126)4.27710694
43protein polyglutamylation (GO:0018095)4.25698943
44DNA deamination (GO:0045006)4.14783366
45chromosome condensation (GO:0030261)4.08422812
46protein localization to cilium (GO:0061512)4.08220731
47ether metabolic process (GO:0018904)4.07756191
48spermatid nucleus differentiation (GO:0007289)4.07206345
49DNA packaging (GO:0006323)4.04367490
50meiosis I (GO:0007127)3.96793917
51intraciliary transport (GO:0042073)3.92929357
52axoneme assembly (GO:0035082)3.92259104
53meiotic cell cycle (GO:0051321)3.73104665
54cellular ketone body metabolic process (GO:0046950)3.71826936
55multicellular organismal development (GO:0007275)3.71433653
56fucose catabolic process (GO:0019317)3.66764519
57L-fucose metabolic process (GO:0042354)3.66764519
58L-fucose catabolic process (GO:0042355)3.66764519
59nucleoside diphosphate phosphorylation (GO:0006165)3.60333859
60single strand break repair (GO:0000012)3.54796902
61water-soluble vitamin biosynthetic process (GO:0042364)3.47184270
62sequestering of actin monomers (GO:0042989)3.44326512
63microtubule-based movement (GO:0007018)3.44171092
64chaperone-mediated protein complex assembly (GO:0051131)3.43053943
65gonadal mesoderm development (GO:0007506)3.40396007
66ketone body metabolic process (GO:1902224)3.37308371
67cilium organization (GO:0044782)3.34838052
68negative regulation of organelle assembly (GO:1902116)3.33517654
69indolalkylamine metabolic process (GO:0006586)3.32883210
70protein refolding (GO:0042026)3.32680990
71tryptophan catabolic process (GO:0006569)3.30206185
72indole-containing compound catabolic process (GO:0042436)3.30206185
73indolalkylamine catabolic process (GO:0046218)3.30206185
74genitalia morphogenesis (GO:0035112)3.28903413
75preassembly of GPI anchor in ER membrane (GO:0016254)3.28655544
76detection of light stimulus involved in visual perception (GO:0050908)3.27476485
77detection of light stimulus involved in sensory perception (GO:0050962)3.27476485
78detection of mechanical stimulus involved in sensory perception of sound (GO:0050910)3.26544360
79glycolytic process (GO:0006096)3.25731205
80platelet dense granule organization (GO:0060155)3.25147070
81cilium assembly (GO:0042384)3.23422771
82kynurenine metabolic process (GO:0070189)3.22417230
83sexual reproduction (GO:0019953)3.16634877
84GTP biosynthetic process (GO:0006183)3.15846994
85photoreceptor cell maintenance (GO:0045494)3.09475404
86protein complex biogenesis (GO:0070271)3.04167377
87cellular component assembly involved in morphogenesis (GO:0010927)3.01590007
88retinal cone cell development (GO:0046549)3.01306943
89cornea development in camera-type eye (GO:0061303)3.00878232
90gamma-aminobutyric acid transport (GO:0015812)2.96770832
91primary amino compound metabolic process (GO:1901160)2.95957326
92microtubule polymerization or depolymerization (GO:0031109)2.94248499
93regulation of spindle checkpoint (GO:0090231)2.92472483
94NADH dehydrogenase complex assembly (GO:0010257)2.90980271
95mitochondrial respiratory chain complex I biogenesis (GO:0097031)2.90980271
96mitochondrial respiratory chain complex I assembly (GO:0032981)2.90980271
97mannosylation (GO:0097502)2.90548357
98regulation of action potential (GO:0098900)2.90501600
99cilium morphogenesis (GO:0060271)2.87669531
100lactate metabolic process (GO:0006089)2.86044079
101mitochondrial respiratory chain complex assembly (GO:0033108)2.83207417
102nonmotile primary cilium assembly (GO:0035058)2.83035967
103respiratory chain complex IV assembly (GO:0008535)2.81856665
104amino-acid betaine transport (GO:0015838)2.80549028
105carnitine transport (GO:0015879)2.80549028
106indole-containing compound metabolic process (GO:0042430)2.80392722
107tryptophan metabolic process (GO:0006568)2.79983184
108meiotic cell cycle process (GO:1903046)2.79104624
109UTP biosynthetic process (GO:0006228)2.77734599
110serotonin metabolic process (GO:0042428)2.76604048
111monoubiquitinated protein deubiquitination (GO:0035520)2.74361841
112G-protein coupled glutamate receptor signaling pathway (GO:0007216)2.73138345
113sulfation (GO:0051923)2.72976232
114regulation of meiosis I (GO:0060631)2.72477537
115regulation of response to osmotic stress (GO:0047484)2.71230883
116left/right axis specification (GO:0070986)2.70580919
117cellular response to ATP (GO:0071318)2.70520081
118neural tube formation (GO:0001841)2.69328696
119mitochondrion degradation (GO:0000422)2.68659415
120carnitine transmembrane transport (GO:1902603)2.67443628
121regulation of cilium assembly (GO:1902017)2.65860830
122nucleus organization (GO:0006997)2.65235653
123alditol metabolic process (GO:0019400)2.64690666
124rRNA catabolic process (GO:0016075)2.64645903
125RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394)2.64072173
126tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388)2.64072173
127RNA localization (GO:0006403)2.62265720
128gene silencing by RNA (GO:0031047)2.60702346
129centriole replication (GO:0007099)2.59713589
130negative regulation of mast cell activation (GO:0033004)2.59434590
131protein K11-linked deubiquitination (GO:0035871)2.58960732
132cytochrome complex assembly (GO:0017004)2.58855047
133reflex (GO:0060004)2.58335176
134peptidyl-glutamic acid modification (GO:0018200)2.57619441
135photoreceptor cell development (GO:0042461)2.57366398
136polyol catabolic process (GO:0046174)2.57155176
137microtubule bundle formation (GO:0001578)2.54479154
138RNA phosphodiester bond hydrolysis, exonucleolytic (GO:0090503)2.54088980
139calcium ion import (GO:0070509)2.53491647
140auditory receptor cell stereocilium organization (GO:0060088)2.53163600
141neuronal action potential (GO:0019228)2.53007549
142behavioral response to ethanol (GO:0048149)2.52545209
143phosphatidylinositol acyl-chain remodeling (GO:0036149)2.52068097
144spinal cord motor neuron differentiation (GO:0021522)2.48990938
145negative regulation of T cell differentiation in thymus (GO:0033085)2.48919921
146positive regulation of meiosis (GO:0045836)2.48555415
147synapsis (GO:0007129)2.48026413
148membrane depolarization during action potential (GO:0086010)2.47279556
149polyamine biosynthetic process (GO:0006596)2.46932346
150negative regulation of telomere maintenance (GO:0032205)2.46700435
151adaptation of signaling pathway (GO:0023058)2.45411305
152negative regulation of synaptic transmission, GABAergic (GO:0032229)2.44824805
153GPI anchor metabolic process (GO:0006505)2.44103072
154regulation of rhodopsin mediated signaling pathway (GO:0022400)2.41932998
155pseudouridine synthesis (GO:0001522)2.41600246
156dopamine transport (GO:0015872)2.40607439
157replication fork processing (GO:0031297)2.39999294
158protein-cofactor linkage (GO:0018065)2.38888430
159thyroid hormone metabolic process (GO:0042403)2.38078664
160rhodopsin mediated signaling pathway (GO:0016056)2.37687323
161regulation of neurotransmitter uptake (GO:0051580)2.36910540
162mitochondrial electron transport, NADH to ubiquinone (GO:0006120)2.35602313
163transmission of nerve impulse (GO:0019226)2.35423805
164sperm motility (GO:0030317)13.1554341
165fusion of sperm to egg plasma membrane (GO:0007342)11.8510804
166acrosome reaction (GO:0007340)11.2041972
167axonemal dynein complex assembly (GO:0070286)10.9113309
168cilium or flagellum-dependent cell motility (GO:0001539)10.6869254
169cell wall macromolecule metabolic process (GO:0044036)10.4560709
170cell wall macromolecule catabolic process (GO:0016998)10.4560709
171epithelial cilium movement (GO:0003351)10.3704987
172sperm-egg recognition (GO:0035036)10.1660080

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse8.60951494
2EZH2_22144423_ChIP-Seq_EOC_Human5.58436940
3TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse3.65857896
4GLI1_17442700_ChIP-ChIP_MESCs_Mouse3.13731222
5GBX2_23144817_ChIP-Seq_PC3_Human2.84834892
6BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse2.73578843
7PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse2.65581821
8FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse2.57838002
9VDR_22108803_ChIP-Seq_LS180_Human2.53088437
10ZFP57_27257070_Chip-Seq_ESCs_Mouse2.32175693
11GATA1_26923725_Chip-Seq_HPCs_Mouse2.28101891
12STAT6_21828071_ChIP-Seq_BEAS2B_Human2.19685607
13IGF1R_20145208_ChIP-Seq_DFB_Human2.14651571
14FUS_26573619_Chip-Seq_HEK293_Human2.13366688
15CTBP1_25329375_ChIP-Seq_LNCAP_Human2.10175931
16POU3F2_20337985_ChIP-ChIP_501MEL_Human2.09413569
17ZNF274_21170338_ChIP-Seq_K562_Hela2.00779093
18CREM_20920259_ChIP-Seq_GC1-SPG_Mouse1.99716765
19P300_19829295_ChIP-Seq_ESCs_Human1.95746802
20REST_21632747_ChIP-Seq_MESCs_Mouse1.93532651
21ER_23166858_ChIP-Seq_MCF-7_Human1.91197664
22EWS_26573619_Chip-Seq_HEK293_Human1.87913137
23GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.87867126
24CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human1.86220532
25ZFP322A_24550733_ChIP-Seq_MESCs_Mouse1.81133863
26EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human1.78817619
27HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human1.78639972
28ELK4_26923725_Chip-Seq_MESODERM_Mouse1.77887101
29MEIS1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse1.59494530
30SOX2_22085726_ChIP-Seq_NPCs_Mouse1.59258449
31CEBPD_23245923_ChIP-Seq_MEFs_Mouse1.58094913
32WDR5_24793694_ChIP-Seq_LNCAP_Human1.56918863
33STAT1_17558387_ChIP-Seq_HELA_Human1.55427367
34SIN3B_21632747_ChIP-Seq_MESCs_Mouse1.55328942
35TAL1_21186366_ChIP-Seq_BM-HSCs_Mouse1.55025209
36SMAD4_21799915_ChIP-Seq_A2780_Human1.54873967
37AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human1.54255144
38STAT3_23295773_ChIP-Seq_U87_Human1.53772834
39FLI1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.53624826
40BMI1_23680149_ChIP-Seq_NPCS_Mouse1.53615685
41UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human1.51537129
42KLF4_25985364_ChIP-Seq_ATHEROSCLEROSIS_LESION_Mouse1.50266468
43FOXA1_27270436_Chip-Seq_PROSTATE_Human1.47886389
44FOXA1_25329375_ChIP-Seq_VCAP_Human1.47886389
45BCAT_22108803_ChIP-Seq_LS180_Human1.46446778
46FLI1_27457419_Chip-Seq_LIVER_Mouse1.45699701
47TP53_22573176_ChIP-Seq_HFKS_Human1.44588908
48AR_25329375_ChIP-Seq_VCAP_Human1.44301139
49TCF4_23295773_ChIP-Seq_U87_Human1.43957610
50NR3C1_21868756_ChIP-Seq_MCF10A_Human1.43568097
51GABP_17652178_ChIP-ChIP_JURKAT_Human1.42251013
52GATA3_21867929_ChIP-Seq_CD8_Mouse1.41836067
53IRF1_19129219_ChIP-ChIP_H3396_Human1.41532678
54MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human1.40264234
55RCOR3_21632747_ChIP-Seq_MESCs_Mouse1.39702973
56GATA2_21186366_ChIP-Seq_BM-HSCs_Mouse1.39676863
57TAL1_26923725_Chip-Seq_HPCs_Mouse1.39378097
58PBX_27287812_Chip-Seq_EMBYONIC-LIMB_Mouse1.37853118
59SOX2_19829295_ChIP-Seq_ESCs_Human1.37606253
60NANOG_19829295_ChIP-Seq_ESCs_Human1.37606253
61RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.36939085
62SALL1_21062744_ChIP-ChIP_HESCs_Human1.36667266
63MYC_18940864_ChIP-ChIP_HL60_Human1.36163147
64IRF4_20064451_ChIP-Seq_CD4+T_Mouse1.36145576
65CBP_20019798_ChIP-Seq_JUKART_Human1.36145576
66SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.35604933
67HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse1.34981752
68TOP2B_26459242_ChIP-Seq_MCF-7_Human1.34562592
69CTBP2_25329375_ChIP-Seq_LNCAP_Human1.34030540
70FLI1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse1.31915682
71PIAS1_25552417_ChIP-Seq_VCAP_Human1.31306016
72KDM2B_26808549_Chip-Seq_REH_Human1.31191176
73TCF4_22108803_ChIP-Seq_LS180_Human1.29401072
74SMAD3_21741376_ChIP-Seq_EPCs_Human1.29270091
75PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.29099364
76KLF5_20875108_ChIP-Seq_MESCs_Mouse1.29058068
77PCGF2_27294783_Chip-Seq_ESCs_Mouse1.28943998
78NCOR_22424771_ChIP-Seq_293T_Human1.28549222
79ZNF652_21678463_ChIP-ChIP_ZR75-1_Human1.28033567
80FOXA1_21572438_ChIP-Seq_LNCaP_Human1.26227477
81YY1_22570637_ChIP-Seq_MALME-3M_Human1.25007536
82GATA3_21878914_ChIP-Seq_MCF-7_Human1.24473436
83GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse1.23478262
84POU5F1_26923725_Chip-Seq_MESODERM_Mouse1.21677582
85TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.21677582
86RAD21_21589869_ChIP-Seq_MESCs_Mouse1.21515404
87AUTS2_25519132_ChIP-Seq_293T-REX_Human1.20243581
88CBX2_27304074_Chip-Seq_ESCs_Mouse1.20210355
89P53_21459846_ChIP-Seq_SAOS-2_Human1.20193955
90CDX2_22108803_ChIP-Seq_LS180_Human1.20076379
91NOTCH1_21737748_ChIP-Seq_TLL_Human1.19555915
92TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.18953099
93SUZ12_27294783_Chip-Seq_NPCs_Mouse1.18710795
94LUZP1_20508642_ChIP-Seq_ESCs_Mouse1.18292539
95PRDM14_20953172_ChIP-Seq_ESCs_Human1.18103446
96KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human1.17185335
97GATA3_21867929_ChIP-Seq_TH1_Mouse1.17115992
98RUNX2_22187159_ChIP-Seq_PCA_Human1.17106605
99AR_20517297_ChIP-Seq_VCAP_Human1.17061814
100EZH2_27294783_Chip-Seq_NPCs_Mouse1.14896588
101MYC_27129775_Chip-Seq_CORNEA_Mouse1.14874703
102MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.14618430
103FLI1_21867929_ChIP-Seq_TH2_Mouse1.14590499
104SETDB1_19884257_ChIP-Seq_MESCs_Mouse1.14238847
105RNF2_27304074_Chip-Seq_NSC_Mouse1.14178455
106HOXB7_26014856_ChIP-Seq_BT474_Human1.13333618
107RCOR2_21632747_ChIP-Seq_MESCs_Mouse1.12689212
108NR4A2_19515692_ChIP-ChIP_MN9D_Mouse1.12396521
109GF1_26923725_Chip-Seq_HPCs_Mouse1.12275275
110RCOR1_19997604_ChIP-ChIP_NEURONS_Mouse1.12022858
111PBX1_22567123_ChIP-ChIP_OVCAR3_Human1.11506773
112ETV2_25802403_ChIP-Seq_MESCs_Mouse1.10624239
113TAF15_26573619_Chip-Seq_HEK293_Human1.09818865
114CEBPB_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse1.08792227
115PHF8_20622853_ChIP-Seq_HELA_Human1.07791175
116TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human1.07467200
117ETV1_20927104_ChIP-Seq_GIST48_Human1.07304897
118ERG_20517297_ChIP-Seq_VCAP_Human1.05866411
119SPI1_26923725_Chip-Seq_HPCs_Mouse1.05509578
120KAP1_22055183_ChIP-Seq_ESCs_Mouse1.05504333
121ESET_19884257_ChIP-Seq_ESCs_Mouse1.04753009
122E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse1.04607505
123CTCF_27219007_Chip-Seq_Bcells_Human1.03939359
124REST_18959480_ChIP-ChIP_MESCs_Mouse1.03050232
125CEBPA_26348894_ChIP-Seq_LIVER_Mouse1.02880631
126SUZ12_27294783_Chip-Seq_ESCs_Mouse1.02812475
127STAT3_18555785_ChIP-Seq_MESCs_Mouse1.02015209
128MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human1.01422372
129EST1_17652178_ChIP-ChIP_JURKAT_Human1.01192849
130RBPJ_21746931_ChIP-Seq_IB4_Human1.01126203
131SPI1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.00875151
132TET1_21451524_ChIP-Seq_MESCs_Mouse1.00653827
133DROSHA_22980978_ChIP-Seq_HELA_Human1.00270933
134TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse0.99886836
135SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse0.99190020
136FOXH1_21741376_ChIP-Seq_EPCs_Human0.99179005
137SRY_22984422_ChIP-ChIP_TESTIS_Rat0.99088628
138P53_22387025_ChIP-Seq_ESCs_Mouse0.99035143
139PCGF4_22325352_ChIP-Seq_293T-Rex_Human0.98298665
140EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human0.98260697
141SMAD2/3_21741376_ChIP-Seq_EPCs_Human0.98166961
142EBNA1_20929547_Chip-Seq_RAJI-cells_Human0.97428528
143RXRA_24833708_ChIP-Seq_LIVER_Mouse0.96019516
144RUNX1_26923725_Chip-Seq_HPCs_Mouse0.95921961
145SOX2_21211035_ChIP-Seq_LN229_Human0.95896485
146CEBPB_26923725_Chip-Seq_MACROPHAGESS_Mouse0.95687853
147CTCF_20526341_ChIP-Seq_ESCs_Human0.95518222
148ELF1_20517297_ChIP-Seq_JURKAT_Human0.94403597
149SMAD3_21741376_ChIP-Seq_ESCs_Human0.93178293
150NFE2_27457419_Chip-Seq_LIVER_Mouse0.92966938
151PPARG_20176806_ChIP-Seq_3T3-L1_Mouse0.92608200
152SIN3A_21632747_ChIP-Seq_MESCs_Mouse0.90749154
153PHF8_20622854_ChIP-Seq_HELA_Human0.90590629
154TBL1_22424771_ChIP-Seq_293T_Human0.89479375
155SMC4_20622854_ChIP-Seq_HELA_Human0.89138037
156JARID1B-DAIN_22020125_ChIP-Seq_ESCs_Mouse0.89073795
157FLI1_21867929_ChIP-Seq_CD8_Mouse0.88417242
158NANOG_20526341_ChIP-Seq_ESCs_Human0.87532350
159MYC_19829295_ChIP-Seq_ESCs_Human0.87063176
160NEUROD2_26341353_ChIP-Seq_CORTEX_Mouse0.86197955
161PCGF2_27294783_Chip-Seq_NPCs_Mouse0.86026737
162LDB1_21186366_ChIP-Seq_BM-HSCs_Mouse0.85763168
163SMAD4_21741376_ChIP-Seq_EPCs_Human0.85196179
164OCT1_27270436_Chip-Seq_PROSTATE_Human0.85007449
165MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse0.84798544
166NANOG_18555785_Chip-Seq_ESCs_Mouse0.84156044
167GATA1_19941827_ChIP-Seq_MEL86_Mouse0.84003800

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0003698_abnormal_male_reproductive5.64251074
2MP0001929_abnormal_gametogenesis5.10014512
3MP0008877_abnormal_DNA_methylation4.09962781
4MP0005670_abnormal_white_adipose3.38657105
5MP0002653_abnormal_ependyma_morphology3.21770003
6MP0002210_abnormal_sex_determination3.18182788
7MP0002161_abnormal_fertility/fecundity3.07908277
8MP0001145_abnormal_male_reproductive2.72916957
9MP0003195_calcinosis2.49966562
10MP0000653_abnormal_sex_gland2.34165105
11MP0008875_abnormal_xenobiotic_pharmacok2.08364609
12MP0002876_abnormal_thyroid_physiology2.05253650
13MP0005410_abnormal_fertilization14.5578064
14MP0006072_abnormal_retinal_apoptosis1.95882136
15MP0008872_abnormal_physiological_respon1.94260585
16MP0002837_dystrophic_cardiac_calcinosis1.92640895
17MP0004043_abnormal_pH_regulation1.90510343
18MP0005623_abnormal_meninges_morphology1.74675637
19MP0010386_abnormal_urinary_bladder1.70733469
20MP0002160_abnormal_reproductive_system1.68769827
21MP0003646_muscle_fatigue1.68036347
22MP0004233_abnormal_muscle_weight1.66105597
23MP0004859_abnormal_synaptic_plasticity1.63882557
24MP0003718_maternal_effect1.63539785
25MP0002138_abnormal_hepatobiliary_system1.63165884
26MP0004142_abnormal_muscle_tone1.58165465
27MP0004147_increased_porphyrin_level1.56177839
28MP0000372_irregular_coat_pigmentation1.53668951
29MP0005645_abnormal_hypothalamus_physiol1.50781811
30MP0000631_abnormal_neuroendocrine_gland1.48284225
31MP0002638_abnormal_pupillary_reflex1.44578683
32MP0002282_abnormal_trachea_morphology1.40981803
33MP0005084_abnormal_gallbladder_morpholo1.38023949
34MP0001986_abnormal_taste_sensitivity1.36384719
35MP0003011_delayed_dark_adaptation1.35164611
36MP0002938_white_spotting1.33484350
37MP0008789_abnormal_olfactory_epithelium1.33082292
38MP0000383_abnormal_hair_follicle1.32064682
39MP0001765_abnormal_ion_homeostasis1.27195065
40MP0003880_abnormal_central_pattern1.26744671
41MP0002102_abnormal_ear_morphology1.25589745
42MP0000427_abnormal_hair_cycle1.25445435
43MP0004270_analgesia1.24303339
44MP0009046_muscle_twitch1.21310734
45MP0008995_early_reproductive_senescence1.15484793
46MP0001905_abnormal_dopamine_level1.12261948
47MP0001984_abnormal_olfaction1.07132969
48MP0002736_abnormal_nociception_after1.06991594
49MP0008058_abnormal_DNA_repair1.04800834
50MP0003635_abnormal_synaptic_transmissio1.03485139
51MP0002277_abnormal_respiratory_mucosa1.00727725
52MP0001968_abnormal_touch/_nociception1.00091388
53MP0002234_abnormal_pharynx_morphology0.99708692
54MP0003879_abnormal_hair_cell0.95888764
55MP0002735_abnormal_chemical_nociception0.95515738
56MP0005195_abnormal_posterior_eye0.94942136
57MP0005379_endocrine/exocrine_gland_phen0.94515455
58MP0001919_abnormal_reproductive_system0.94489675
59MP0004924_abnormal_behavior0.90802072
60MP0005386_behavior/neurological_phenoty0.90802072
61MP0002063_abnormal_learning/memory/cond0.90526470
62MP0005332_abnormal_amino_acid0.89397597
63MP0002572_abnormal_emotion/affect_behav0.87222529
64MP0003136_yellow_coat_color0.86027735
65MP0002272_abnormal_nervous_system0.83168669
66MP0003878_abnormal_ear_physiology0.82822528
67MP0005377_hearing/vestibular/ear_phenot0.82822528
68MP0000026_abnormal_inner_ear0.79690696
69MP0001440_abnormal_grooming_behavior0.79368307
70MP0002095_abnormal_skin_pigmentation0.79138896
71MP0005389_reproductive_system_phenotype0.78696703
72MP0002163_abnormal_gland_morphology0.78538320
73MP0000230_abnormal_systemic_arterial0.77603966
74MP0009745_abnormal_behavioral_response0.77316298
75MP0003252_abnormal_bile_duct0.77068285
76MP0003806_abnormal_nucleotide_metabolis0.76940158
77MP0004742_abnormal_vestibular_system0.76555771
78MP0001764_abnormal_homeostasis0.76438711
79MP0002269_muscular_atrophy0.76372747
80MP0008775_abnormal_heart_ventricle0.75412608
81MP0005174_abnormal_tail_pigmentation0.74549436
82MP0004133_heterotaxia0.74252195
83MP0003283_abnormal_digestive_organ0.74168586
84MP0001502_abnormal_circadian_rhythm0.73814852
85MP0008961_abnormal_basal_metabolism0.73521574
86MP0003115_abnormal_respiratory_system0.73178552
87MP0005647_abnormal_sex_gland0.71561756
88MP0004811_abnormal_neuron_physiology0.69921294
89MP0002064_seizures0.66497646
90MP0003787_abnormal_imprinting0.66219159
91MP0001293_anophthalmia0.65856816
92MP0000955_abnormal_spinal_cord0.64240734
93MP0006292_abnormal_olfactory_placode0.63965186
94MP0001486_abnormal_startle_reflex0.61945845
95MP0002067_abnormal_sensory_capabilities0.57635892
96MP0001324_abnormal_eye_pigmentation0.56257846
97MP0004145_abnormal_muscle_electrophysio0.55759633
98MP0006276_abnormal_autonomic_nervous0.55443624
99MP0004885_abnormal_endolymph0.54758507
100MP0008569_lethality_at_weaning0.53640638
101MP0005666_abnormal_adipose_tissue0.53006678
102MP0005636_abnormal_mineral_homeostasis0.51807179
103MP0000015_abnormal_ear_pigmentation0.51640781
104MP0010094_abnormal_chromosome_stability0.51082602
105MP0003633_abnormal_nervous_system0.50526091
106MP0002928_abnormal_bile_duct0.50326901
107MP0003329_amyloid_beta_deposits0.50168024
108MP0005551_abnormal_eye_electrophysiolog0.49112328
109MP0005646_abnormal_pituitary_gland0.48959229
110MP0005075_abnormal_melanosome_morpholog0.48566480
111MP0001485_abnormal_pinna_reflex0.48461578
112MP0002184_abnormal_innervation0.48353909
113MP0002733_abnormal_thermal_nociception0.47796593
114MP0002152_abnormal_brain_morphology0.46719107
115MP0002734_abnormal_mechanical_nocicepti0.46697757
116MP0003172_abnormal_lysosome_physiology0.44534919
117MP0002229_neurodegeneration0.44118516
118MP0002882_abnormal_neuron_morphology0.43949687
119MP0006036_abnormal_mitochondrial_physio0.43916577
120MP0009115_abnormal_fat_cell0.42323554
121MP0003699_abnormal_female_reproductive0.41232488
122MP0000534_abnormal_ureter_morphology0.40819970
123MP0004036_abnormal_muscle_relaxation0.40333027
124MP0000569_abnormal_digit_pigmentation0.40248220
125MP0005253_abnormal_eye_physiology0.39303745
126MP0001970_abnormal_pain_threshold0.39190861
127MP0000358_abnormal_cell_content/0.39114156
128MP0003183_abnormal_peptide_metabolism0.39090707
129MP0003861_abnormal_nervous_system0.38568305
130MP0004264_abnormal_extraembryonic_tissu0.38157706
131MP0002752_abnormal_somatic_nervous0.37035513
132MP0002557_abnormal_social/conspecific_i0.36441385
133MP0003631_nervous_system_phenotype0.36325473
134MP0002066_abnormal_motor_capabilities/c0.36025860
135MP0003045_fibrosis0.35317463
136MP0004858_abnormal_nervous_system0.34873761
137MP0001501_abnormal_sleep_pattern0.34743464
138MP0000751_myopathy0.33620413
139MP0000749_muscle_degeneration0.32966667
140MP0001963_abnormal_hearing_physiology0.32647101
141MP0002169_no_abnormal_phenotype0.30928030

Predicted human phenotypes

RankGene SetZ-score
1Abnormal respiratory motile cilium physiology (HP:0012261)9.63742546
2Abnormal respiratory epithelium morphology (HP:0012253)9.21920558
3Abnormal respiratory motile cilium morphology (HP:0005938)9.21920558
4Rhinitis (HP:0012384)7.88806260
5Abnormal ciliary motility (HP:0012262)7.78820405
6Chronic bronchitis (HP:0004469)7.22457082
7Infertility (HP:0000789)6.74363366
8Nasal polyposis (HP:0100582)5.87437907
9Male infertility (HP:0003251)5.21669993
10Abnormality of the nasal mucosa (HP:0000433)4.93470290
11Pancreatic cysts (HP:0001737)4.78601705
12Bronchiectasis (HP:0002110)4.58815649
13Nephronophthisis (HP:0000090)4.26529577
14Bronchitis (HP:0012387)4.25734512
15Congenital stationary night blindness (HP:0007642)3.54054904
16Chronic hepatic failure (HP:0100626)3.41595927
17Abnormality of the renal medulla (HP:0100957)3.15326678
18Abnormality of the lower motor neuron (HP:0002366)3.14245749
19Recurrent otitis media (HP:0000403)3.07243664
20Abnormal spermatogenesis (HP:0008669)3.06326228
21Recurrent sinusitis (HP:0011108)2.93557128
22Attenuation of retinal blood vessels (HP:0007843)2.88870386
23Pendular nystagmus (HP:0012043)2.75095395
24Abnormality of midbrain morphology (HP:0002418)2.70993739
25Molar tooth sign on MRI (HP:0002419)2.70993739
26Tubulointerstitial nephritis (HP:0001970)2.69293574
27Abnormal rod and cone electroretinograms (HP:0008323)2.67500647
28Medial flaring of the eyebrow (HP:0010747)2.62009515
29Sclerocornea (HP:0000647)2.61142260
30Abolished electroretinogram (ERG) (HP:0000550)2.59524635
31Abnormal gallbladder physiology (HP:0012438)2.53791006
32Cholecystitis (HP:0001082)2.53791006
33Furrowed tongue (HP:0000221)2.41752037
34Impulsivity (HP:0100710)2.39703231
35Anencephaly (HP:0002323)2.39655196
36Occipital encephalocele (HP:0002085)2.34779126
37Male pseudohermaphroditism (HP:0000037)2.34069421
38Gonadotropin excess (HP:0000837)2.32704777
39Aplasia/Hypoplasia of the tongue (HP:0010295)2.31762473
40Decreased circulating renin level (HP:0003351)2.30938387
41Recurrent bronchitis (HP:0002837)2.27919465
42Tubular atrophy (HP:0000092)2.27357453
43Acute necrotizing encephalopathy (HP:0006965)2.23672644
44Hyperventilation (HP:0002883)2.22614502
45Tubulointerstitial abnormality (HP:0001969)2.22391115
46Abnormality of pyruvate family amino acid metabolism (HP:0010915)2.20375163
47Abnormality of alanine metabolism (HP:0010916)2.20375163
48Hyperalaninemia (HP:0003348)2.20375163
49Absent rod-and cone-mediated responses on ERG (HP:0007688)2.20076960
50Severe visual impairment (HP:0001141)2.19761125
51Polyuria (HP:0000103)2.14306630
52Genetic anticipation (HP:0003743)2.10741164
53Increased corneal curvature (HP:0100692)2.09738996
54Keratoconus (HP:0000563)2.09738996
55Bony spicule pigmentary retinopathy (HP:0007737)2.08135629
56Renal cortical cysts (HP:0000803)2.07481241
57Congenital sensorineural hearing impairment (HP:0008527)2.07161594
58Acute encephalopathy (HP:0006846)2.05233497
59Mitochondrial inheritance (HP:0001427)2.03871083
60Azoospermia (HP:0000027)2.02769881
61Methylmalonic acidemia (HP:0002912)2.01484427
62Respiratory insufficiency due to defective ciliary clearance (HP:0200073)13.0381106
63Absent/shortened dynein arms (HP:0200106)12.4284959
64Dynein arm defect of respiratory motile cilia (HP:0012255)12.4284959
65Progressive macrocephaly (HP:0004481)1.99171408
66Abnormality of macular pigmentation (HP:0008002)1.98274634
67Increased CSF lactate (HP:0002490)1.97475922
68Decreased electroretinogram (ERG) amplitude (HP:0000654)1.97407972
69Aplasia/Hypoplasia of the spleen (HP:0010451)1.95379301
70Hypoplasia of the uterus (HP:0000013)1.94822591
71Febrile seizures (HP:0002373)1.94571102
72Spastic tetraparesis (HP:0001285)1.93624270
73Congenital, generalized hypertrichosis (HP:0004540)1.93212600
743-Methylglutaconic aciduria (HP:0003535)1.92756233
75Aplasia/hypoplasia of the uterus (HP:0008684)1.90533198
76Postaxial foot polydactyly (HP:0001830)1.89531610
77Asplenia (HP:0001746)1.87209348
78Abnormal mitochondria in muscle tissue (HP:0008316)1.86634658
79Tubulointerstitial fibrosis (HP:0005576)1.79746932
80Methylmalonic aciduria (HP:0012120)1.79531928
81Inability to walk (HP:0002540)1.77444648
82Optic disc pallor (HP:0000543)1.76556196
83Decreased number of large peripheral myelinated nerve fibers (HP:0003387)1.76212203
84Large for gestational age (HP:0001520)1.75758430
85Congenital hepatic fibrosis (HP:0002612)1.75709110
86Preaxial hand polydactyly (HP:0001177)1.75460909
87Chorioretinal atrophy (HP:0000533)1.74821582
88Supernumerary spleens (HP:0009799)1.74296560
89Aplasia/Hypoplasia of the tibia (HP:0005772)1.71473331
90Stage 5 chronic kidney disease (HP:0003774)1.71179254
91Aplasia/Hypoplasia of the optic nerve (HP:0008058)1.69572526
92Aplasia/Hypoplasia of the fovea (HP:0008060)1.69087276
93Hypoplasia of the fovea (HP:0007750)1.69087276
94Oculomotor apraxia (HP:0000657)1.67743882
95Severe muscular hypotonia (HP:0006829)1.67564194
96Progressive inability to walk (HP:0002505)1.66989526
97Congenital primary aphakia (HP:0007707)1.66970892
98Broad-based gait (HP:0002136)1.66735868
99Gait imbalance (HP:0002141)1.66654054
100Polydipsia (HP:0001959)1.65208027
101Abnormal drinking behavior (HP:0030082)1.65208027
102Dyschromatopsia (HP:0007641)1.64816343
103Retinitis pigmentosa (HP:0000510)1.63010849
104Choroideremia (HP:0001139)1.62826426
105Postaxial hand polydactyly (HP:0001162)1.60444197
106Abnormality of renin-angiotensin system (HP:0000847)1.60305994
107Bile duct proliferation (HP:0001408)1.56491825
108Abnormal biliary tract physiology (HP:0012439)1.56491825
109Bundle branch block (HP:0011710)1.52808805
110Heterotopia (HP:0002282)1.52197854
111Decreased central vision (HP:0007663)1.52042761
112Impaired proprioception (HP:0010831)1.49825300
113Abnormality of the renal cortex (HP:0011035)1.47600231
114Amyotrophic lateral sclerosis (HP:0007354)1.47066896
115Abnormality of renal excretion (HP:0011036)1.46335161
116Aplasia/Hypoplasia of the lens (HP:0008063)1.46010977
117Progressive cerebellar ataxia (HP:0002073)1.45977032
118Nephrogenic diabetes insipidus (HP:0009806)1.44311183
119Abnormality of dentin (HP:0010299)1.42448710
120Taurodontia (HP:0000679)1.41359112
121Abnormality of permanent molar morphology (HP:0011071)1.41359112
122Abnormality of the dental root (HP:0006486)1.41359112
123Difficulty climbing stairs (HP:0003551)1.40638075
124Hypoplasia of the capital femoral epiphysis (HP:0003090)1.40376373
125Short ribs (HP:0000773)1.38705644
126Cystic liver disease (HP:0006706)1.35653040
127EMG: neuropathic changes (HP:0003445)1.34920912
128Pancreatic fibrosis (HP:0100732)1.34422021
129Hemiparesis (HP:0001269)1.34269992
130Type II lissencephaly (HP:0007260)1.33735109
131Chronic sinusitis (HP:0011109)1.32905146
132Vaginal atresia (HP:0000148)1.32754516
133Asymmetric septal hypertrophy (HP:0001670)1.32735573
134Retinal dysplasia (HP:0007973)1.31025684
135Genital tract atresia (HP:0001827)1.30448684
136Myokymia (HP:0002411)1.30383074
137Abnormality of molar morphology (HP:0011070)1.28588253
138Abnormality of molar (HP:0011077)1.28588253
139Facial cleft (HP:0002006)1.28205755
140Loss of speech (HP:0002371)1.27042350
141Abnormality of the dental pulp (HP:0006479)1.26975503
142Poor coordination (HP:0002370)1.25256748
143Clumsiness (HP:0002312)1.24992594
144Renal dysplasia (HP:0000110)1.24399312
145Dysmetric saccades (HP:0000641)1.23930481
146Lissencephaly (HP:0001339)1.22589527
147Nephropathy (HP:0000112)1.21956555
148Aplasia/Hypoplasia affecting the fundus (HP:0008057)1.21618072
149Easy fatigability (HP:0003388)1.20230350
150Bulbar palsy (HP:0001283)1.19099943
151Short thorax (HP:0010306)1.18698411
152Abnormality of ocular smooth pursuit (HP:0000617)1.18611123
153Abnormal urine output (HP:0012590)1.18549828
154Exercise-induced myalgia (HP:0003738)1.17043876
155True hermaphroditism (HP:0010459)1.16381176
156Gaze-evoked nystagmus (HP:0000640)1.14831782
157Neoplasm of the heart (HP:0100544)1.14652664
158Cerebellar dysplasia (HP:0007033)1.14312763

Predicted kinase interactions (KEA)

RankGene SetZ-score
1PDK37.23297337
2PDK47.23297337
3FRK5.98344130
4TESK15.71191498
5PRKD35.44328811
6ICK4.74234831
7PDK24.72549990
8ADRBK23.01612181
9MAP4K22.98199490
10GRK12.75952848
11PTK2B2.67172049
12WNK32.36557062
13BMPR1B2.36002749
14PNCK2.32502172
15ZAK2.25618981
16NUAK12.25254027
17INSRR2.25100975
18WNK42.13567410
19STK392.04825480
20MST42.03537867
21TAOK31.98432306
22OXSR11.95137158
23ACVR1B1.94264428
24STK381.82421578
25MAPK131.81569964
26TLK11.75069085
27MAP3K91.71707543
28TXK1.56864523
29MAPK151.53664465
30NEK21.47769639
31PLK21.45403744
32DYRK1B1.40219318
33TRIM281.30648080
34CASK1.26600201
35DAPK21.18709734
36PRKCE1.16570863
37PDK11.15857605
38ADRBK11.11718491
39TYRO31.08712650
40TNIK1.07287765
41ARAF1.05213648
42PHKG21.04978423
43PHKG11.04978423
44MUSK1.03506874
45FLT31.01501792
46DYRK20.99959514
47PAK30.98384518
48PRKCI0.93805347
49VRK20.93570493
50WNK10.92995896
51EIF2AK30.92801094
52RIPK40.91892308
53PLK40.90766615
54MAP3K40.90592136
55VRK10.87450592
56CSNK1G20.87446117
57EEF2K0.85588904
58MKNK20.82130127
59MARK10.81443194
60MAP2K60.80382461
61TEC0.80362178
62PINK10.80079552
63NTRK20.78544707
64NTRK30.78422006
65LMTK20.74466676
66BCKDK0.73193827
67PDPK10.72096986
68DYRK30.72055292
69CSNK1G30.71717341
70EPHA40.71353528
71CSNK1G10.69560966
72MARK20.69255397
73TIE10.68110469
74CDK190.67263668
75PRKCQ0.64756887
76BRAF0.64689336
77GRK50.64543477
78PLK30.61810794
79CAMK1G0.61248780
80CSNK1A1L0.57719606
81BRSK20.56170600
82CAMKK10.55810481
83BCR0.55385576
84PRKCG0.54556723
85CCNB10.53919451
86IKBKB0.52286487
87NME10.51699897
88RPS6KA50.50799374
89MAP2K10.49998515
90CSNK1A10.48485214
91MAP3K120.48220881
92TAOK10.47421749
93MAPKAPK30.45389565
94MAPKAPK50.44496778
95CHEK20.43489473
96PAK10.43128233
97PAK40.43052602
98TTK0.39154666
99ITK0.39098698
100TGFBR10.38148326
101ERBB30.37688167
102PLK10.37627161
103DYRK1A0.37149806
104NEK60.36214314
105KIT0.36092907
106IRAK10.35608778
107STK160.34881720
108PRKG10.34196287
109EIF2AK10.33768404
110PKN10.33401238
111AKT30.33197424
112CSNK1D0.33069681
113CAMK10.32543560
114PIK3CA0.32189995
115GRK70.31607906
116PRKCH0.31501316
117FGFR20.29707243
118MINK10.29448592
119KSR20.29237507
120TNK20.28882291
121CDK180.28845625
122CHEK10.28312324
123CDK11A0.27897951
124CDK150.27633020
125CAMK2A0.27413857
126STK30.26011191
127DAPK10.24637483
128PRKAA10.23501161
129MAP2K70.21410373
130PRKD20.21255889
131MTOR0.21221896
132CDK140.21026191
133MOS0.20000973
134MAP3K130.19490034
135MATK0.18422039
136ATM0.18291837
137PASK0.18158204
138PAK60.17465506
139SIK30.17073853
140CDK50.15921192
141RPS6KB10.15380268
142PRKACB0.14637903
143MAP3K10.14068616
144PRKCZ0.13975471
145TESK20.13158348
146GSK3B0.12760441
147MAP3K60.12715065
148CAMK2B0.10871968
149RPS6KA30.09073979
150MAPK100.08378964
151CAMKK20.08203742
152CDK120.07746798
153STK38L0.07554849
154NTRK10.07260594
155PAK20.07216406
156PRKACG0.06997131
157ATR0.06925708
158FER0.06672042
159CSNK1E0.05981157
160CDC42BPA0.05945684
161RPS6KA10.05797438
162PRKCA0.05343033
163STK110.05263365
164PRKACA0.04691138
165MAP2K40.04521119

Predicted pathways (KEGG)

RankGene SetZ-score
1Fatty acid biosynthesis_Homo sapiens_hsa000613.84152572
2Glycolysis / Gluconeogenesis_Homo sapiens_hsa000103.76019578
3Vitamin B6 metabolism_Homo sapiens_hsa007503.04565637
4Pyruvate metabolism_Homo sapiens_hsa006202.90775600
5alpha-Linolenic acid metabolism_Homo sapiens_hsa005922.75094388
6Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005632.70805241
7Phototransduction_Homo sapiens_hsa047442.70444421
8Linoleic acid metabolism_Homo sapiens_hsa005912.67398543
9Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049642.64557633
10Glucagon signaling pathway_Homo sapiens_hsa049222.32927676
11Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006012.26928440
12Synthesis and degradation of ketone bodies_Homo sapiens_hsa000722.25485699
13Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049612.25164226
14Maturity onset diabetes of the young_Homo sapiens_hsa049502.17940376
15Oxidative phosphorylation_Homo sapiens_hsa001902.11965294
16Fructose and mannose metabolism_Homo sapiens_hsa000512.10760306
17Nitrogen metabolism_Homo sapiens_hsa009102.07822986
18Amphetamine addiction_Homo sapiens_hsa050312.05085874
19RNA polymerase_Homo sapiens_hsa030202.03621451
20Synaptic vesicle cycle_Homo sapiens_hsa047212.01286369
21Collecting duct acid secretion_Homo sapiens_hsa049662.00837587
22Butanoate metabolism_Homo sapiens_hsa006501.99501057
23Carbohydrate digestion and absorption_Homo sapiens_hsa049731.96889623
24Dorso-ventral axis formation_Homo sapiens_hsa043201.93334393
25Oocyte meiosis_Homo sapiens_hsa041141.88722771
26Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005331.86759076
27Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001301.84636557
28Glycerolipid metabolism_Homo sapiens_hsa005611.83709582
29Taurine and hypotaurine metabolism_Homo sapiens_hsa004301.73148001
30Propanoate metabolism_Homo sapiens_hsa006401.72161914
31Long-term potentiation_Homo sapiens_hsa047201.67250079
32Protein export_Homo sapiens_hsa030601.66970474
33Homologous recombination_Homo sapiens_hsa034401.65488371
34Basal transcription factors_Homo sapiens_hsa030221.64476622
35Chemical carcinogenesis_Homo sapiens_hsa052041.61232151
36Huntingtons disease_Homo sapiens_hsa050161.60831154
37Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007601.57594748
38Cardiac muscle contraction_Homo sapiens_hsa042601.57302535
39Parkinsons disease_Homo sapiens_hsa050121.54384257
40Drug metabolism - cytochrome P450_Homo sapiens_hsa009821.49523979
41Tryptophan metabolism_Homo sapiens_hsa003801.48883388
42Glycerophospholipid metabolism_Homo sapiens_hsa005641.46786586
43Caffeine metabolism_Homo sapiens_hsa002321.45948441
44Fanconi anemia pathway_Homo sapiens_hsa034601.45009905
45Protein processing in endoplasmic reticulum_Homo sapiens_hsa041411.37171613
46Renin secretion_Homo sapiens_hsa049241.36088906
47Insulin secretion_Homo sapiens_hsa049111.34502904
48Longevity regulating pathway - multiple species_Homo sapiens_hsa042131.32637903
49Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049601.32093247
50One carbon pool by folate_Homo sapiens_hsa006701.30824072
51Circadian entrainment_Homo sapiens_hsa047131.30087070
52Valine, leucine and isoleucine degradation_Homo sapiens_hsa002801.28443892
53Steroid hormone biosynthesis_Homo sapiens_hsa001401.28279933
54Sulfur metabolism_Homo sapiens_hsa009201.27878652
55Retinol metabolism_Homo sapiens_hsa008301.27847829
56Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050141.27430335
57Ether lipid metabolism_Homo sapiens_hsa005651.26592265
58Ascorbate and aldarate metabolism_Homo sapiens_hsa000531.24900481
59Calcium signaling pathway_Homo sapiens_hsa040201.24801369
60Butirosin and neomycin biosynthesis_Homo sapiens_hsa005241.23839493
61Nicotine addiction_Homo sapiens_hsa050331.21616987
62Salivary secretion_Homo sapiens_hsa049701.21379463
63Mineral absorption_Homo sapiens_hsa049781.17750065
64RNA degradation_Homo sapiens_hsa030181.17216767
65Proteasome_Homo sapiens_hsa030501.13013932
66Peroxisome_Homo sapiens_hsa041461.10025096
67Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030081.08509329
68PPAR signaling pathway_Homo sapiens_hsa033201.07880626
69Alzheimers disease_Homo sapiens_hsa050101.07373460
70Primary bile acid biosynthesis_Homo sapiens_hsa001201.05915955
71Hedgehog signaling pathway_Homo sapiens_hsa043401.05089374
72Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006041.04731490
73Regulation of autophagy_Homo sapiens_hsa041401.04491511
74Fat digestion and absorption_Homo sapiens_hsa049751.01914378
75Olfactory transduction_Homo sapiens_hsa047400.99173139
76Taste transduction_Homo sapiens_hsa047420.98783732
77Selenocompound metabolism_Homo sapiens_hsa004500.98145980
78Serotonergic synapse_Homo sapiens_hsa047260.97243478
79Carbon metabolism_Homo sapiens_hsa012000.94745655
80Glycosaminoglycan degradation_Homo sapiens_hsa005310.93230734
81mRNA surveillance pathway_Homo sapiens_hsa030150.93013998
82Intestinal immune network for IgA production_Homo sapiens_hsa046720.92615870
83Fatty acid metabolism_Homo sapiens_hsa012120.92085490
84cGMP-PKG signaling pathway_Homo sapiens_hsa040220.91211782
85Pancreatic secretion_Homo sapiens_hsa049720.91043168
86Pentose phosphate pathway_Homo sapiens_hsa000300.90406713
87Glutamatergic synapse_Homo sapiens_hsa047240.90239007
88Histidine metabolism_Homo sapiens_hsa003400.87137827
89Purine metabolism_Homo sapiens_hsa002300.86397063
90Estrogen signaling pathway_Homo sapiens_hsa049150.85637074
91beta-Alanine metabolism_Homo sapiens_hsa004100.84373078
92Vasopressin-regulated water reabsorption_Homo sapiens_hsa049620.83190435
93Gastric acid secretion_Homo sapiens_hsa049710.82972420
94Sulfur relay system_Homo sapiens_hsa041220.82232763
95VEGF signaling pathway_Homo sapiens_hsa043700.81532692
96Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042610.81242143
97Biosynthesis of amino acids_Homo sapiens_hsa012300.80429506
98Renin-angiotensin system_Homo sapiens_hsa046140.79762591
99Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.79408170
100Dopaminergic synapse_Homo sapiens_hsa047280.78087697
101cAMP signaling pathway_Homo sapiens_hsa040240.77308063
102Cytosolic DNA-sensing pathway_Homo sapiens_hsa046230.77067572
103Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.76142941
104Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.75530525
105Pentose and glucuronate interconversions_Homo sapiens_hsa000400.74431418
106Phosphatidylinositol signaling system_Homo sapiens_hsa040700.73449401
107Thyroid hormone synthesis_Homo sapiens_hsa049180.73187057
108RNA transport_Homo sapiens_hsa030130.73013000
109Arachidonic acid metabolism_Homo sapiens_hsa005900.72634868
110Cysteine and methionine metabolism_Homo sapiens_hsa002700.70830001
111Pyrimidine metabolism_Homo sapiens_hsa002400.70636947
112Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049320.68174172
113Vascular smooth muscle contraction_Homo sapiens_hsa042700.67748147
114Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.66585679
115Morphine addiction_Homo sapiens_hsa050320.64068304
116Fatty acid degradation_Homo sapiens_hsa000710.63694463
117Endocytosis_Homo sapiens_hsa041440.62097454
118Oxytocin signaling pathway_Homo sapiens_hsa049210.61646751
119Nucleotide excision repair_Homo sapiens_hsa034200.60686201
120Primary immunodeficiency_Homo sapiens_hsa053400.58899728
121Type I diabetes mellitus_Homo sapiens_hsa049400.57483765
122Central carbon metabolism in cancer_Homo sapiens_hsa052300.56672463
123Ovarian steroidogenesis_Homo sapiens_hsa049130.56231887
124Tyrosine metabolism_Homo sapiens_hsa003500.55431705
125Inositol phosphate metabolism_Homo sapiens_hsa005620.54252524
126Adipocytokine signaling pathway_Homo sapiens_hsa049200.50669126
127Asthma_Homo sapiens_hsa053100.49920349
128Citrate cycle (TCA cycle)_Homo sapiens_hsa000200.49758724
129Aldosterone synthesis and secretion_Homo sapiens_hsa049250.48183419
130Bile secretion_Homo sapiens_hsa049760.46978221
131Thyroid hormone signaling pathway_Homo sapiens_hsa049190.46894345
132Glutathione metabolism_Homo sapiens_hsa004800.46641921
133Retrograde endocannabinoid signaling_Homo sapiens_hsa047230.46417250
134Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047500.46167490
135SNARE interactions in vesicular transport_Homo sapiens_hsa041300.43853949
136Cytokine-cytokine receptor interaction_Homo sapiens_hsa040600.42699281
137Vibrio cholerae infection_Homo sapiens_hsa051100.42516996
138Wnt signaling pathway_Homo sapiens_hsa043100.41968722
139Cocaine addiction_Homo sapiens_hsa050300.40969229
140Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.40161390
141Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.39347206
142AMPK signaling pathway_Homo sapiens_hsa041520.39210117
143Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.38775061
144Antigen processing and presentation_Homo sapiens_hsa046120.38707531
145Drug metabolism - other enzymes_Homo sapiens_hsa009830.36849657
146Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.35031218
147Protein digestion and absorption_Homo sapiens_hsa049740.34185474
148Graft-versus-host disease_Homo sapiens_hsa053320.33682185
149Circadian rhythm_Homo sapiens_hsa047100.32872500
150Other glycan degradation_Homo sapiens_hsa005110.32086617
151Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.31050831
152Cyanoamino acid metabolism_Homo sapiens_hsa004600.30734017
153Non-homologous end-joining_Homo sapiens_hsa034500.30545493
154Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.30088847
155GABAergic synapse_Homo sapiens_hsa047270.29532580
156ABC transporters_Homo sapiens_hsa020100.27259744
157Metabolic pathways_Homo sapiens_hsa011000.25306216

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