ST18

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1axon ensheathment in central nervous system (GO:0032291)7.61248545
2central nervous system myelination (GO:0022010)7.61248545
3negative regulation of neurotransmitter secretion (GO:0046929)4.76802141
4behavioral response to nicotine (GO:0035095)4.56058530
5fatty acid elongation (GO:0030497)4.40745039
6myelination (GO:0042552)4.37072085
7ensheathment of neurons (GO:0007272)4.35569660
8axon ensheathment (GO:0008366)4.35569660
9pyrimidine nucleobase catabolic process (GO:0006208)4.17953806
10negative regulation of neurotransmitter transport (GO:0051589)4.01621278
11apical protein localization (GO:0045176)3.98451262
12photoreceptor cell differentiation (GO:0046530)3.96232880
13eye photoreceptor cell differentiation (GO:0001754)3.96232880
14ionotropic glutamate receptor signaling pathway (GO:0035235)3.95341209
15endocrine pancreas development (GO:0031018)3.90181431
16nucleobase catabolic process (GO:0046113)3.88597017
17ER overload response (GO:0006983)3.87415260
18long-chain fatty acid biosynthetic process (GO:0042759)3.87185484
19negative regulation of cytosolic calcium ion concentration (GO:0051481)3.83175906
20axonal fasciculation (GO:0007413)3.82456153
21positive regulation of oligodendrocyte differentiation (GO:0048714)3.72523510
22regulation of inhibitory postsynaptic membrane potential (GO:0060080)3.70910846
23gamma-aminobutyric acid transport (GO:0015812)3.70298137
24neurotransmitter-gated ion channel clustering (GO:0072578)3.68321231
25asymmetric protein localization (GO:0008105)3.67254305
26peptidyl-tyrosine autophosphorylation (GO:0038083)3.67024265
27regulation of short-term neuronal synaptic plasticity (GO:0048172)3.65150829
28synaptic transmission, glutamatergic (GO:0035249)3.59495778
29glutamate receptor signaling pathway (GO:0007215)3.58584996
30neuron recognition (GO:0008038)3.57170912
31presynaptic membrane organization (GO:0097090)3.57158761
32proline transport (GO:0015824)3.49745814
33magnesium ion transport (GO:0015693)3.45112506
34membrane depolarization during cardiac muscle cell action potential (GO:0086012)3.43792557
35presynaptic membrane assembly (GO:0097105)3.41411449
36response to redox state (GO:0051775)3.38023717
37oligodendrocyte differentiation (GO:0048709)3.37036463
38forebrain neuron differentiation (GO:0021879)3.34689928
39postsynaptic membrane organization (GO:0001941)3.29144665
40positive regulation of calcium ion-dependent exocytosis (GO:0045956)3.27882942
41neuron-neuron synaptic transmission (GO:0007270)3.27601786
42regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway (GO:19022353.25930190
43G-protein coupled glutamate receptor signaling pathway (GO:0007216)3.25600739
44glycerophospholipid catabolic process (GO:0046475)3.25463387
45Golgi transport vesicle coating (GO:0048200)3.24154511
46COPI coating of Golgi vesicle (GO:0048205)3.24154511
47startle response (GO:0001964)3.23816574
48synapse assembly (GO:0007416)3.22878372
49response to pheromone (GO:0019236)3.22830893
50glandular epithelial cell differentiation (GO:0002067)3.21925024
51astrocyte differentiation (GO:0048708)3.20285398
52protein palmitoylation (GO:0018345)3.19401776
53neuronal action potential (GO:0019228)3.17083995
54synaptic vesicle docking involved in exocytosis (GO:0016081)3.16337600
55myelin maintenance (GO:0043217)3.15954263
56neuromuscular synaptic transmission (GO:0007274)3.15307529
57negative regulation of JUN kinase activity (GO:0043508)3.14427726
58glutamate secretion (GO:0014047)3.14218816
59membrane depolarization during action potential (GO:0086010)3.14047589
60urinary tract smooth muscle contraction (GO:0014848)3.12814761
61response to lipoprotein particle (GO:0055094)3.10552271
62negative regulation of synaptic transmission, glutamatergic (GO:0051967)3.10211481
63peptide hormone processing (GO:0016486)3.01767569
64establishment of mitochondrion localization (GO:0051654)2.97462549
65neuron cell-cell adhesion (GO:0007158)2.96870354
66positive regulation of excitatory postsynaptic membrane potential (GO:2000463)2.96858779
67cranial nerve development (GO:0021545)2.95158972
68regulation of collateral sprouting (GO:0048670)2.94582448
69cerebellar granule cell differentiation (GO:0021707)2.94498025
70transmission of nerve impulse (GO:0019226)2.93705048
71detection of light stimulus involved in sensory perception (GO:0050962)2.92602370
72detection of light stimulus involved in visual perception (GO:0050908)2.92602370
73negative regulation of dendrite development (GO:2000171)2.91939257
74regulation of respiratory gaseous exchange by neurological system process (GO:0002087)2.91813235
75detection of calcium ion (GO:0005513)2.91726352
76neurotransmitter secretion (GO:0007269)2.90249457
77adult walking behavior (GO:0007628)2.89375310
78protein localization to synapse (GO:0035418)2.89250164
79regulation of synaptic vesicle exocytosis (GO:2000300)2.87824875
80insulin secretion (GO:0030073)2.86559243
81auditory behavior (GO:0031223)2.84006674
82reflex (GO:0060004)2.82509739
83cellular ketone body metabolic process (GO:0046950)2.82171966
84inositol phosphate catabolic process (GO:0071545)2.81626143
85creatine metabolic process (GO:0006600)2.80798789
86glycosphingolipid biosynthetic process (GO:0006688)2.79559894
87regulation of transcription involved in cell fate commitment (GO:0060850)2.79400693
88protein polyglutamylation (GO:0018095)2.79389168
89response to hepatocyte growth factor (GO:0035728)2.79280063
90cellular response to hepatocyte growth factor stimulus (GO:0035729)2.79280063
91regulation of respiratory system process (GO:0044065)2.78049153
92regulation of type B pancreatic cell apoptotic process (GO:2000674)2.77781171
93neuronal action potential propagation (GO:0019227)2.75697855
94serotonin metabolic process (GO:0042428)2.75351153
95cerebellar Purkinje cell differentiation (GO:0021702)2.75339750
96dendritic spine morphogenesis (GO:0060997)2.75273611
97vocalization behavior (GO:0071625)2.75120027
98L-amino acid import (GO:0043092)2.74444377
99spinal cord motor neuron differentiation (GO:0021522)2.74406320
100behavioral response to ethanol (GO:0048149)2.73600830
101response to methylmercury (GO:0051597)2.73540490
102negative regulation of execution phase of apoptosis (GO:1900118)2.73009260
103cholesterol biosynthetic process (GO:0006695)2.72093059
104dendrite morphogenesis (GO:0048813)2.71395252
105synaptic vesicle exocytosis (GO:0016079)2.70938653
106protein maturation by protein folding (GO:0022417)2.68715360
107negative regulation of synaptic transmission, GABAergic (GO:0032229)2.67580163
108locomotory exploration behavior (GO:0035641)2.67516469
109primary amino compound metabolic process (GO:1901160)2.67145011
110dopamine biosynthetic process (GO:0042416)2.66033418
111calcium ion import (GO:0070509)2.64922219
112signal peptide processing (GO:0006465)2.64669934
113positive regulation of insulin secretion (GO:0032024)2.64294791
114retinal ganglion cell axon guidance (GO:0031290)2.64240607
115adult behavior (GO:0030534)2.63418456
116regulation of synaptic transmission, glutamatergic (GO:0051966)2.62755749
117positive regulation of action potential (GO:0045760)2.62560110
118type B pancreatic cell development (GO:0003323)2.62504257
119regulation of N-methyl-D-aspartate selective glutamate receptor activity (GO:2000310)2.62479793
120protein localization to cilium (GO:0061512)2.61371689
121regulation of neurotransmitter transport (GO:0051588)2.61274904
122action potential (GO:0001508)2.60232547
123positive regulation of synaptic transmission, dopaminergic (GO:0032226)2.60221896
124long-chain fatty-acyl-CoA biosynthetic process (GO:0035338)2.58806776
125nucleotide transmembrane transport (GO:1901679)2.58717278
126response to auditory stimulus (GO:0010996)2.57691373
127negative regulation of protein localization to cell surface (GO:2000009)2.57309173
128gamma-aminobutyric acid signaling pathway (GO:0007214)2.57294998
129positive regulation of neurotransmitter transport (GO:0051590)2.56966107
130response to dietary excess (GO:0002021)2.56961711
131regulation of neurotransmitter uptake (GO:0051580)2.56687951
132neuron fate specification (GO:0048665)2.56612799
133regulation of synapse structural plasticity (GO:0051823)2.55415832
134righting reflex (GO:0060013)2.55181801
135regulation of cilium movement (GO:0003352)2.54869140
136nerve growth factor signaling pathway (GO:0038180)2.54817343
137central nervous system projection neuron axonogenesis (GO:0021952)2.54394879
138regulation of action potential (GO:0098900)2.54065637
139tachykinin receptor signaling pathway (GO:0007217)2.53937131
140ganglion development (GO:0061548)2.53245804
141mechanosensory behavior (GO:0007638)2.52924853
142central nervous system neuron axonogenesis (GO:0021955)2.52803193
143mating behavior (GO:0007617)2.52164711
144regulation of neurotransmitter secretion (GO:0046928)2.52088707
145substantia nigra development (GO:0021762)2.51411076
146ear development (GO:0043583)2.50701146
147astrocyte development (GO:0014002)2.50685322
148adult locomotory behavior (GO:0008344)2.50298540
149regulation of synaptic transmission, GABAergic (GO:0032228)2.49904093
150membrane hyperpolarization (GO:0060081)2.49649752
151regulation of insulin secretion (GO:0050796)2.49591083
152calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules (GO:0016339)2.49000776
153regulation of postsynaptic membrane potential (GO:0060078)2.48792495
154regulation of calcium ion-dependent exocytosis (GO:0017158)2.48738376
155dentate gyrus development (GO:0021542)2.48619657
156nonmotile primary cilium assembly (GO:0035058)2.48409074
157negative regulation of axonogenesis (GO:0050771)2.46075411
158neuron fate determination (GO:0048664)2.45520821
159regulation of autophagic vacuole assembly (GO:2000785)2.45044547
160GPI anchor metabolic process (GO:0006505)2.43877967
161regulation of dopamine metabolic process (GO:0042053)2.43458611
162regulation of catecholamine metabolic process (GO:0042069)2.43458611
163cerebral cortex radially oriented cell migration (GO:0021799)2.43050251
164positive regulation of glial cell differentiation (GO:0045687)2.42596600
165substrate-independent telencephalic tangential interneuron migration (GO:0021843)2.41987081
166substrate-independent telencephalic tangential migration (GO:0021826)2.41987081
167protein targeting to Golgi (GO:0000042)2.39485610
168Golgi to plasma membrane protein transport (GO:0043001)2.38415145
169neuronal ion channel clustering (GO:0045161)2.37570865
170glycosylceramide metabolic process (GO:0006677)2.37414085
171cell differentiation in hindbrain (GO:0021533)2.36123944
172synaptic vesicle maturation (GO:0016188)2.35747181
173amyloid precursor protein metabolic process (GO:0042982)2.35135682
174Golgi to endosome transport (GO:0006895)2.35034776
175potassium ion homeostasis (GO:0055075)2.34767548
176chemosensory behavior (GO:0007635)2.32495332

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1GBX2_23144817_ChIP-Seq_PC3_Human3.52683145
2EZH2_22144423_ChIP-Seq_EOC_Human2.59188546
3FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse2.40596033
4GLI1_17442700_ChIP-ChIP_MESCs_Mouse2.35246215
5SUZ12_18692474_ChIP-Seq_MESCs_Mouse2.33027582
6SUZ12_18555785_ChIP-Seq_MESCs_Mouse2.28241236
7EZH2_27304074_Chip-Seq_ESCs_Mouse2.14002713
8JARID2_20064375_ChIP-Seq_MESCs_Mouse2.07900257
9* SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse2.06845132
10IGF1R_20145208_ChIP-Seq_DFB_Human2.06218135
11SUZ12_20075857_ChIP-Seq_MESCs_Mouse2.05769814
12* REST_21632747_ChIP-Seq_MESCs_Mouse2.04931552
13TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse2.04785931
14EZH2_27294783_Chip-Seq_ESCs_Mouse2.04454123
15MTF2_20144788_ChIP-Seq_MESCs_Mouse1.96046674
16POU3F2_20337985_ChIP-ChIP_501MEL_Human1.95480218
17DROSHA_22980978_ChIP-Seq_HELA_Human1.94838769
18OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.89510531
19SUZ12_27294783_Chip-Seq_ESCs_Mouse1.89032961
20SUZ12_18692474_ChIP-Seq_MEFs_Mouse1.87145963
21* ZFP57_27257070_Chip-Seq_ESCs_Mouse1.85712460
22JARID2_20075857_ChIP-Seq_MESCs_Mouse1.83689560
23GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.81213611
24SUZ12_16625203_ChIP-ChIP_MESCs_Mouse1.80198642
25EZH2_18974828_ChIP-Seq_MESCs_Mouse1.78520759
26RNF2_18974828_ChIP-Seq_MESCs_Mouse1.78520759
27EED_16625203_ChIP-ChIP_MESCs_Mouse1.75995905
28RNF2_27304074_Chip-Seq_ESCs_Mouse1.74105146
29PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.73390555
30ZFP322A_24550733_ChIP-Seq_MESCs_Mouse1.71115424
31SUZ12_18974828_ChIP-Seq_MESCs_Mouse1.70409973
32VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human1.69084552
33PIAS1_25552417_ChIP-Seq_VCAP_Human1.68663940
34CTBP2_25329375_ChIP-Seq_LNCAP_Human1.65824052
35* REST_18959480_ChIP-ChIP_MESCs_Mouse1.57261190
36BMI1_23680149_ChIP-Seq_NPCS_Mouse1.57093331
37SMAD3_21741376_ChIP-Seq_EPCs_Human1.56021614
38* STAT3_23295773_ChIP-Seq_U87_Human1.53336869
39ER_23166858_ChIP-Seq_MCF-7_Human1.53015349
40AR_25329375_ChIP-Seq_VCAP_Human1.52475508
41TAF15_26573619_Chip-Seq_HEK293_Human1.51437671
42TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.50815688
43POU5F1_26923725_Chip-Seq_MESODERM_Mouse1.50815688
44SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.50490135
45CBX2_27304074_Chip-Seq_ESCs_Mouse1.48618815
46RARB_27405468_Chip-Seq_BRAIN_Mouse1.47767734
47* CTBP1_25329375_ChIP-Seq_LNCAP_Human1.47656573
48PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse1.45654219
49CEBPD_23245923_ChIP-Seq_MEFs_Mouse1.45239685
50SMAD4_21799915_ChIP-Seq_A2780_Human1.44369800
51EWS_26573619_Chip-Seq_HEK293_Human1.43765442
52MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse1.42842106
53DMRT1_21621532_ChIP-ChIP_FETAL_Ovary1.42301932
54CDX2_19796622_ChIP-Seq_MESCs_Mouse1.40765068
55VDR_22108803_ChIP-Seq_LS180_Human1.39590082
56* FLI1_27457419_Chip-Seq_LIVER_Mouse1.36408059
57BCAT_22108803_ChIP-Seq_LS180_Human1.35618241
58P300_19829295_ChIP-Seq_ESCs_Human1.35119283
59AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human1.35100622
60UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human1.33177102
61RNF2_16625203_ChIP-ChIP_MESCs_Mouse1.32780015
62NR3C1_23031785_ChIP-Seq_PC12_Mouse1.31780966
63BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse1.31462270
64OLIG2_26023283_ChIP-Seq_AINV15_Mouse1.29713576
65* NANOG_18555785_Chip-Seq_ESCs_Mouse1.29227936
66TCF4_23295773_ChIP-Seq_U87_Human1.28988298
67IRF4_20064451_ChIP-Seq_CD4+T_Mouse1.27866188
68CBP_20019798_ChIP-Seq_JUKART_Human1.27866188
69PHC1_16625203_ChIP-ChIP_MESCs_Mouse1.25471002
70TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.25463225
71SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.23713818
72P53_22127205_ChIP-Seq_FIBROBLAST_Human1.23030004
73FUS_26573619_Chip-Seq_HEK293_Human1.22940466
74* TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse1.22254060
75AR_21572438_ChIP-Seq_LNCaP_Human1.20924364
76STAT3_24763339_ChIP-Seq_IMN-ESCs_Mouse1.20261267
77* RNF2_27304074_Chip-Seq_NSC_Mouse1.18510446
78TOP2B_26459242_ChIP-Seq_MCF-7_Human1.18321865
79SOX2_21211035_ChIP-Seq_LN229_Gbm1.17876096
80* PCGF2_27294783_Chip-Seq_ESCs_Mouse1.16698942
81* CMYC_18555785_Chip-Seq_ESCs_Mouse1.14907988
82LMO2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.14753619
83GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse1.14683458
84SALL1_21062744_ChIP-ChIP_HESCs_Human1.12984139
85ZNF217_24962896_ChIP-Seq_MCF-7_Human1.12731786
86CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons1.12725143
87* SUZ12_27294783_Chip-Seq_NPCs_Mouse1.11946321
88* PDX1_19855005_ChIP-ChIP_MIN6_Mouse1.10269303
89NR4A2_19515692_ChIP-ChIP_MN9D_Mouse1.10183712
90* EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse1.09022889
91* SUZ12_18555785_Chip-Seq_ESCs_Mouse1.08995462
92TCF4_22108803_ChIP-Seq_LS180_Human1.08694705
93TAL1_26923725_Chip-Seq_HPCs_Mouse1.08233605
94KLF5_20875108_ChIP-Seq_MESCs_Mouse1.07494556
95MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human1.06905498
96PRDM14_20953172_ChIP-Seq_ESCs_Human1.06801714
97RCOR2_21632747_ChIP-Seq_MESCs_Mouse1.05697686
98TP53_22573176_ChIP-Seq_HFKS_Human1.04809862
99EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human1.04368691
100RCOR1_19997604_ChIP-ChIP_NEURONS_Mouse1.04205600
101RING1B_27294783_Chip-Seq_ESCs_Mouse1.03950201
102* RUNX2_22187159_ChIP-Seq_PCA_Human1.03371165
103NR3C1_21868756_ChIP-Seq_MCF10A_Human1.02982521
104TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human1.02830779
105ZNF274_21170338_ChIP-Seq_K562_Hela1.01753546
106PCGF2_27294783_Chip-Seq_NPCs_Mouse1.01406080
107* P300_18555785_Chip-Seq_ESCs_Mouse1.01247251
108MEIS1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse1.01015247
109YAP1_20516196_ChIP-Seq_MESCs_Mouse1.00598504
110SMAD4_21741376_ChIP-Seq_EPCs_Human1.00147230
111LMO2_26923725_Chip-Seq_MACROPHAGESS_Mouse0.99864735
112WT1_25993318_ChIP-Seq_PODOCYTE_Human0.99809458
113* P53_22387025_ChIP-Seq_ESCs_Mouse0.99232685
114FLI1_21867929_ChIP-Seq_TH2_Mouse0.99135903
115* STAT3_18555785_Chip-Seq_ESCs_Mouse0.97515157
116TEAD4_22529382_ChIP-Seq_TROPHECTODERM_Mouse0.96982475
117SOX9_26525672_Chip-Seq_Limbbuds_Mouse0.96660940
118SMAD3_21741376_ChIP-Seq_ESCs_Human0.95691107
119* E2F1_18555785_Chip-Seq_ESCs_Mouse0.95584202
120WT1_19549856_ChIP-ChIP_CCG9911_Human0.95375668
121ERA_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human0.95284699
122RING1B_27294783_Chip-Seq_NPCs_Mouse0.94547191
123* SOX2_18555785_Chip-Seq_ESCs_Mouse0.94037574

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0004043_abnormal_pH_regulation3.24186644
2MP0004270_analgesia3.20786440
3MP0000920_abnormal_myelination3.19894194
4MP0006072_abnormal_retinal_apoptosis2.79315693
5MP0001968_abnormal_touch/_nociception2.49753578
6MP0003183_abnormal_peptide_metabolism2.49053818
7MP0000013_abnormal_adipose_tissue2.43837204
8MP0009780_abnormal_chondrocyte_physiolo2.40836216
9MP0010386_abnormal_urinary_bladder2.39579845
10MP0005551_abnormal_eye_electrophysiolog2.27697469
11MP0003195_calcinosis2.23548394
12MP0002272_abnormal_nervous_system2.18933029
13MP0000569_abnormal_digit_pigmentation2.18459408
14MP0004859_abnormal_synaptic_plasticity2.15433961
15MP0003283_abnormal_digestive_organ2.09861427
16MP0003880_abnormal_central_pattern2.08636107
17MP0001486_abnormal_startle_reflex2.05421979
18MP0002064_seizures1.96583829
19MP0002909_abnormal_adrenal_gland1.95289186
20MP0004742_abnormal_vestibular_system1.93698035
21MP0004885_abnormal_endolymph1.93391423
22MP0003634_abnormal_glial_cell1.89262112
23MP0009046_muscle_twitch1.87373300
24MP0003635_abnormal_synaptic_transmissio1.87365409
25MP0003690_abnormal_glial_cell1.85281415
26MP0002734_abnormal_mechanical_nocicepti1.84886656
27MP0008877_abnormal_DNA_methylation1.84659685
28MP0005379_endocrine/exocrine_gland_phen1.82718204
29MP0003950_abnormal_plasma_membrane1.82707971
30MP0005645_abnormal_hypothalamus_physiol1.81547761
31MP0005646_abnormal_pituitary_gland1.79253121
32MP0001501_abnormal_sleep_pattern1.77636826
33MP0002693_abnormal_pancreas_physiology1.76394045
34MP0002229_neurodegeneration1.76122986
35MP0005253_abnormal_eye_physiology1.75350740
36MP0001502_abnormal_circadian_rhythm1.72048058
37MP0001944_abnormal_pancreas_morphology1.71323754
38MP0002736_abnormal_nociception_after1.69652751
39MP0000778_abnormal_nervous_system1.69419387
40MP0004145_abnormal_muscle_electrophysio1.67168377
41MP0000631_abnormal_neuroendocrine_gland1.65585395
42MP0004142_abnormal_muscle_tone1.64046933
43MP0000462_abnormal_digestive_system1.61347620
44MP0001529_abnormal_vocalization1.59200920
45MP0000955_abnormal_spinal_cord1.57837630
46MP0005423_abnormal_somatic_nervous1.56970825
47MP0001346_abnormal_lacrimal_gland1.55407636
48MP0003329_amyloid_beta_deposits1.53009592
49MP0009745_abnormal_behavioral_response1.51835405
50MP0001485_abnormal_pinna_reflex1.50376725
51MP0002638_abnormal_pupillary_reflex1.49263225
52MP0002572_abnormal_emotion/affect_behav1.46916417
53MP0002877_abnormal_melanocyte_morpholog1.45870704
54MP0000003_abnormal_adipose_tissue1.44945207
55MP0002822_catalepsy1.44457677
56MP0008569_lethality_at_weaning1.41504554
57MP0002063_abnormal_learning/memory/cond1.40385911
58MP0002067_abnormal_sensory_capabilities1.39240579
59MP0002090_abnormal_vision1.38824739
60MP0001661_extended_life_span1.38666796
61MP0002184_abnormal_innervation1.37917383
62MP0002882_abnormal_neuron_morphology1.37755025
63MP0001299_abnormal_eye_distance/1.37743789
64MP0005171_absent_coat_pigmentation1.37560607
65MP0001905_abnormal_dopamine_level1.37319132
66MP0003121_genomic_imprinting1.34175580
67MP0004133_heterotaxia1.30890891
68MP0005220_abnormal_exocrine_pancreas1.28356478
69MP0004147_increased_porphyrin_level1.21989181
70MP0003632_abnormal_nervous_system1.20517379
71MP0006292_abnormal_olfactory_placode1.19030421
72MP0001986_abnormal_taste_sensitivity1.18714522
73MP0001970_abnormal_pain_threshold1.18582315
74MP0003633_abnormal_nervous_system1.17100147
75MP0002557_abnormal_social/conspecific_i1.16115043
76MP0002733_abnormal_thermal_nociception1.14377086
77MP0002066_abnormal_motor_capabilities/c1.12820400
78MP0000678_abnormal_parathyroid_gland1.12680465
79MP0003890_abnormal_embryonic-extraembry1.11910103
80MP0002876_abnormal_thyroid_physiology1.11434414
81MP0004924_abnormal_behavior1.11187798
82MP0005386_behavior/neurological_phenoty1.11187798
83MP0008872_abnormal_physiological_respon1.10929709
84MP0005195_abnormal_posterior_eye1.10319297
85MP0002752_abnormal_somatic_nervous1.06077975
86MP0003631_nervous_system_phenotype1.05727436
87MP0002234_abnormal_pharynx_morphology1.05345933
88MP0003879_abnormal_hair_cell1.04142648
89MP0005187_abnormal_penis_morphology1.02572404
90MP0008995_early_reproductive_senescence1.00991987
91MP0002653_abnormal_ependyma_morphology0.99893435
92MP0005409_darkened_coat_color0.99317326
93MP0001963_abnormal_hearing_physiology0.99001202
94MP0001984_abnormal_olfaction0.97025989
95MP0003172_abnormal_lysosome_physiology0.96594557
96MP0002078_abnormal_glucose_homeostasis0.95295700
97MP0003122_maternal_imprinting0.94154141
98MP0001188_hyperpigmentation0.93809631
99MP0002163_abnormal_gland_morphology0.92912540
100MP0001440_abnormal_grooming_behavior0.91341869
101MP0004811_abnormal_neuron_physiology0.91302845
102MP0002102_abnormal_ear_morphology0.90941296
103MP0002928_abnormal_bile_duct0.89637552
104MP0005058_abnormal_lysosome_morphology0.89327027
105MP0003123_paternal_imprinting0.88906797
106MP0002152_abnormal_brain_morphology0.87421952
107MP0000566_synostosis0.84804735
108MP0002837_dystrophic_cardiac_calcinosis0.83404225
109MP0004134_abnormal_chest_morphology0.81374951
110MP0002160_abnormal_reproductive_system0.81187246
111MP0003787_abnormal_imprinting0.81092450
112MP0005410_abnormal_fertilization0.80375893
113MP0008789_abnormal_olfactory_epithelium0.79632815
114MP0002069_abnormal_eating/drinking_beha0.78585752
115MP0002751_abnormal_autonomic_nervous0.78050969
116MP0005535_abnormal_body_temperature0.76104482
117MP0003119_abnormal_digestive_system0.74680426
118MP0002735_abnormal_chemical_nociception0.74606831
119MP0000427_abnormal_hair_cycle0.74144413
120MP0003137_abnormal_impulse_conducting0.72686614
121MP0005394_taste/olfaction_phenotype0.71839094
122MP0005499_abnormal_olfactory_system0.71839094
123MP0005391_vision/eye_phenotype0.70056839
124MP0006276_abnormal_autonomic_nervous0.69711348
125MP0000026_abnormal_inner_ear0.69551325

Predicted human phenotypes

RankGene SetZ-score
1Neurofibrillary tangles (HP:0002185)4.48227390
2Hyperinsulinemic hypoglycemia (HP:0000825)4.29117762
3Atrophy/Degeneration involving the corticospinal tracts (HP:0007372)4.26903452
4Degeneration of the lateral corticospinal tracts (HP:0002314)4.26903452
5Elevated circulating parathyroid hormone (PTH) level (HP:0003165)4.16138788
6Focal motor seizures (HP:0011153)4.11504974
7Hypoglycemic seizures (HP:0002173)3.99415758
8Large for gestational age (HP:0001520)3.72658765
9Focal seizures (HP:0007359)3.56082438
10Symptomatic seizures (HP:0011145)3.55313062
11Pancreatic islet-cell hyperplasia (HP:0004510)3.46310935
12Congenital stationary night blindness (HP:0007642)3.42341205
13Anteriorly placed anus (HP:0001545)3.41891432
14Febrile seizures (HP:0002373)3.39015864
15Pheochromocytoma (HP:0002666)3.37511771
16Hyperventilation (HP:0002883)3.37451495
17Abnormality of the corticospinal tract (HP:0002492)3.26935722
18Genetic anticipation (HP:0003743)3.21222575
19Broad-based gait (HP:0002136)3.15744274
20Abnormality of endocrine pancreas physiology (HP:0012093)3.15193546
21Abnormality of the pancreatic islet cells (HP:0006476)3.15193546
22Intracellular accumulation of autofluorescent lipopigment storage material (HP:0003204)3.11736983
23Supranuclear gaze palsy (HP:0000605)3.10227225
24Nephronophthisis (HP:0000090)3.07744091
25Cerebral inclusion bodies (HP:0100314)3.02906446
26Split foot (HP:0001839)2.99651941
27Abnormality of midbrain morphology (HP:0002418)2.98708165
28Molar tooth sign on MRI (HP:0002419)2.98708165
29Gaze-evoked nystagmus (HP:0000640)2.94893399
30Retinal dysplasia (HP:0007973)2.94458783
31Limb dystonia (HP:0002451)2.91586392
32Agitation (HP:0000713)2.84572041
33Hypoplasia of the fovea (HP:0007750)2.84485464
34Aplasia/Hypoplasia of the fovea (HP:0008060)2.84485464
35Increased circulating renin level (HP:0000848)2.82487606
36Spastic gait (HP:0002064)2.81721103
37Neuroendocrine neoplasm (HP:0100634)2.81274478
38Abnormality of calcium-phosphate metabolism (HP:0100530)2.80150912
39Alacrima (HP:0000522)2.75755183
40EEG with generalized epileptiform discharges (HP:0011198)2.72903879
41Intention tremor (HP:0002080)2.71918621
42Abnormality of the renal medulla (HP:0100957)2.67826916
43Pancreatic fibrosis (HP:0100732)2.67192940
44Dialeptic seizures (HP:0011146)2.64642558
45Epileptiform EEG discharges (HP:0011182)2.61683641
46Dysmetria (HP:0001310)2.60675685
47Pancreatic cysts (HP:0001737)2.60427680
48Hypsarrhythmia (HP:0002521)2.58225669
49Septo-optic dysplasia (HP:0100842)2.54339796
50Insulin-resistant diabetes mellitus (HP:0000831)2.54013267
51Abnormality of the fovea (HP:0000493)2.52454236
52Epileptic encephalopathy (HP:0200134)2.49043848
53Nephrogenic diabetes insipidus (HP:0009806)2.48216910
54Thickened helices (HP:0000391)2.47656400
55Absent speech (HP:0001344)2.47225131
56Sensory axonal neuropathy (HP:0003390)2.46339597
57Polyphagia (HP:0002591)2.44926194
58Scanning speech (HP:0002168)2.44430257
59Action tremor (HP:0002345)2.43379581
60Onion bulb formation (HP:0003383)2.40675125
61Congenital sensorineural hearing impairment (HP:0008527)2.39353568
62Hepatoblastoma (HP:0002884)2.38048925
63Peripheral hypomyelination (HP:0007182)2.37152993
64True hermaphroditism (HP:0010459)2.36526967
65Hypothermia (HP:0002045)2.34520315
66Decreased circulating renin level (HP:0003351)2.33691306
67Abnormality of macular pigmentation (HP:0008002)2.32864475
68Hypoglycemic coma (HP:0001325)2.31259796
69Central scotoma (HP:0000603)2.31093531
70Generalized tonic-clonic seizures (HP:0002069)2.30598291
71Ankle clonus (HP:0011448)2.28447774
72Type II lissencephaly (HP:0007260)2.27671835
73Decreased lacrimation (HP:0000633)2.27398845
74Abnormal pancreas size (HP:0012094)2.27098014
75Absent septum pellucidum (HP:0001331)2.26324620
76Chronic hepatic failure (HP:0100626)2.25554944
77Inability to walk (HP:0002540)2.24377784
78Hyperkalemia (HP:0002153)2.19644210
79Parakeratosis (HP:0001036)2.18502568
80Abnormality of the renal cortex (HP:0011035)2.17720869
81Ketoacidosis (HP:0001993)2.17719799
82Cerebral hypomyelination (HP:0006808)2.17523543
83Absence seizures (HP:0002121)2.17235259
84Polydipsia (HP:0001959)2.16642002
85Abnormal drinking behavior (HP:0030082)2.16642002
86Abnormality of renin-angiotensin system (HP:0000847)2.13987976
87Visual hallucinations (HP:0002367)2.13333424
88Methylmalonic acidemia (HP:0002912)2.13178134
89Progressive cerebellar ataxia (HP:0002073)2.12374209
90Protruding tongue (HP:0010808)2.10788359
91Macroorchidism (HP:0000053)2.10016326
92Megalencephaly (HP:0001355)2.09130463
93Hemiparesis (HP:0001269)2.09109541
94Lissencephaly (HP:0001339)2.07709628
95Urinary bladder sphincter dysfunction (HP:0002839)2.06136955
96Hypokalemia (HP:0002900)2.04190314
97Optic nerve hypoplasia (HP:0000609)2.03973329
98Bony spicule pigmentary retinopathy (HP:0007737)2.03331367
99Hyperglycemia (HP:0003074)2.02546239
100Truncal ataxia (HP:0002078)2.01933814
101Abnormality of potassium homeostasis (HP:0011042)2.01542397
102Abolished electroretinogram (ERG) (HP:0000550)2.00909674
103Poor coordination (HP:0002370)2.00628256
104Prolonged QT interval (HP:0001657)2.00587145
105Abnormal eating behavior (HP:0100738)1.99842453
106Medial flaring of the eyebrow (HP:0010747)1.98878654
107Specific learning disability (HP:0001328)1.98118977
108Osteomalacia (HP:0002749)1.97920583
109Abnormality of the parathyroid morphology (HP:0011766)1.97558581
110Amblyopia (HP:0000646)1.97361279
111Abnormal auditory evoked potentials (HP:0006958)1.97272461
112Double outlet right ventricle (HP:0001719)1.94834591
113Congenital malformation of the right heart (HP:0011723)1.94834591
114Termporal pattern (HP:0011008)1.94517149
115Insidious onset (HP:0003587)1.94517149
116Vaginal atresia (HP:0000148)1.94401184
117Gait imbalance (HP:0002141)1.92349748
118Cupped ear (HP:0000378)1.92055748
119Hypomagnesemia (HP:0002917)1.91477135
120Clonus (HP:0002169)1.90330702
121Impaired vibration sensation in the lower limbs (HP:0002166)1.90078640
122Progressive inability to walk (HP:0002505)1.89909756
123Atonic seizures (HP:0010819)1.89671757
124Dysostosis multiplex (HP:0000943)1.88269635
125Intestinal atresia (HP:0011100)1.88214217
126Cortical visual impairment (HP:0100704)1.87858358
127Myokymia (HP:0002411)1.87525646
128Progressive neurologic deterioration (HP:0002344)1.87310934
129Retinal atrophy (HP:0001105)1.86600505
130Abnormality of the septum pellucidum (HP:0007375)1.86110257
131Genital tract atresia (HP:0001827)1.85974372
132Muscular hypotonia of the trunk (HP:0008936)1.85022067
133Cystic liver disease (HP:0006706)1.84686334
134Morphological abnormality of the pyramidal tract (HP:0002062)1.84038933
135Decreased central vision (HP:0007663)1.83140718
136Spastic tetraplegia (HP:0002510)1.83047981
137Anxiety (HP:0000739)1.82185632
138Postural tremor (HP:0002174)1.81461546
139Abnormality of the labia minora (HP:0012880)1.80560769
140Status epilepticus (HP:0002133)1.78490207
141Abnormal rod and cone electroretinograms (HP:0008323)1.78481118
142Tubulointerstitial nephritis (HP:0001970)1.78384168
143Dysdiadochokinesis (HP:0002075)1.78051700
144Excessive salivation (HP:0003781)1.77998164
145Drooling (HP:0002307)1.77998164
146Neoplasm of the adrenal cortex (HP:0100641)1.77463841
147Aqueductal stenosis (HP:0002410)1.77104625
148Congenital primary aphakia (HP:0007707)1.76852845
149Pachygyria (HP:0001302)1.76817072
150Poor speech (HP:0002465)1.76091546
151Aplasia/Hypoplasia affecting the retina (HP:0008061)1.75619037
152Lower limb muscle weakness (HP:0007340)1.75228545
153Metabolic alkalosis (HP:0200114)1.75114355
154Diplopia (HP:0000651)1.73826763
155Abnormality of binocular vision (HP:0011514)1.73826763
156Choreoathetosis (HP:0001266)1.73739928
157Aplasia/hypoplasia of the uterus (HP:0008684)1.72630743
158Amyotrophic lateral sclerosis (HP:0007354)1.72051278
159Oligodactyly (hands) (HP:0001180)1.71867259
160Tubular atrophy (HP:0000092)1.70702111
161Abnormality of vitamin B metabolism (HP:0004340)1.70539132
162Widely spaced teeth (HP:0000687)1.70480401
163Thyroid-stimulating hormone excess (HP:0002925)1.68608322
164Fair hair (HP:0002286)1.67705792
165Progressive macrocephaly (HP:0004481)1.66753729
166Attenuation of retinal blood vessels (HP:0007843)1.66645320

Predicted kinase interactions (KEA)

RankGene SetZ-score
1INSRR4.31560366
2STK393.91885589
3OXSR13.04551686
4MAPK152.58126724
5EPHB12.56478266
6WNK42.53520640
7UHMK12.47711672
8ADRBK22.33202461
9DAPK22.26352549
10BCR2.18234378
11WNK12.08386371
12EPHA42.05261511
13HIPK22.00582295
14PRPF4B1.97863139
15PINK11.88332330
16WNK31.85528318
17PRKD31.79946641
18MAP4K21.79820082
19MAP3K21.79717295
20NEK61.78866418
21TNIK1.78546664
22PASK1.77996537
23PKN11.74479489
24PAK61.71021630
25MET1.70749717
26MAP2K71.66563520
27TAOK31.60791461
28NTRK11.55248018
29FGFR21.54433132
30MARK11.50872508
31PBK1.48936273
32SGK4941.47736742
33SGK2231.47736742
34CDK191.44196594
35CAMK2D1.42437670
36NTRK31.42210851
37GRK11.39846998
38MINK11.39466099
39CAMK2B1.36758426
40PNCK1.35568124
41MAPKAPK51.33202796
42CSNK1A1L1.32959907
43PAK31.32559393
44IRAK21.22746468
45BMPR1B1.14882351
46CSNK1G31.12564524
47CASK1.12046118
48ICK1.10600817
49SGK21.07280260
50EPHA31.05239498
51STK111.04176812
52ERBB31.03907763
53SIK20.97975233
54CDK50.96807266
55CSNK1G20.96454834
56PRKCH0.96320415
57BRD40.93873108
58IRAK10.93871749
59MARK20.93151808
60DYRK20.93013371
61CAMKK20.92496404
62PRKCE0.91826749
63ACVR1B0.90686032
64PLK20.88437225
65LIMK10.88211015
66CDC42BPA0.86553880
67FRK0.85322750
68CSNK1G10.85270168
69CLK10.84220231
70ROCK20.83138348
71DYRK1A0.82519481
72MKNK20.81113788
73CAMK10.81036986
74CAMKK10.78761421
75PRKD20.78529677
76MAP2K40.77941525
77CAMK2A0.73988443
78PRKCZ0.73635368
79MAPK130.73591232
80CAMK2G0.70904701
81CAMK1G0.68773941
82ADRBK10.66178784
83PHKG20.65302442
84PHKG10.65302442
85YES10.64395582
86CDK140.63823043
87TAOK10.61858477
88PRKG10.61841958
89PRKD10.61729107
90CSNK1A10.60671131
91NTRK20.58772719
92PTK20.58426318
93PTK2B0.57581971
94MAP3K10.57519501
95RPS6KA50.56830163
96CDK150.55905520
97KSR20.55038014
98CAMK40.54805761
99CSNK1D0.52949853
100CDK180.52737114
101PRKCQ0.52668174
102DYRK1B0.52494890
103STK38L0.51488788
104BMPR20.51101038
105MAP3K40.50489531
106AKT30.49886829
107TYRO30.48912193
108CDK11A0.48046862
109FGR0.47902137
110PRKAA10.47266474
111MAP3K90.47022647
112CDK30.45805588
113GSK3A0.45728349
114DYRK30.45684396
115SGK10.44807644
116SGK30.44500912
117MAP2K60.44436464
118RPS6KA30.44166866
119FYN0.44005327
120ROCK10.43803723
121PDPK10.43734634
122MAPK100.42869411
123PRKACA0.40607752
124CSNK1E0.40575265
125FES0.40315367
126ITK0.39952610
127CAMK1D0.39786189
128KSR10.38782103
129TRIM280.38645259
130ERBB40.38642926
131PRKCG0.38481478
132BRAF0.38298409
133PRKACB0.34554788
134PDGFRB0.34284339
135MAP2K20.33448521
136PRKCA0.33123802
137ERBB20.31766157
138FER0.30179271
139PRKCB0.29653421
140GSK3B0.29417920
141STK380.28955337
142ZAK0.28054508

Predicted pathways (KEGG)

RankGene SetZ-score
1Maturity onset diabetes of the young_Homo sapiens_hsa049505.04673674
2Protein export_Homo sapiens_hsa030603.78428034
3Terpenoid backbone biosynthesis_Homo sapiens_hsa009003.13691025
4Sulfur metabolism_Homo sapiens_hsa009202.59804529
5Insulin secretion_Homo sapiens_hsa049112.48858784
6Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005632.30531358
7Steroid biosynthesis_Homo sapiens_hsa001002.21826165
8Fatty acid elongation_Homo sapiens_hsa000622.19598372
9GABAergic synapse_Homo sapiens_hsa047272.16763039
10Ether lipid metabolism_Homo sapiens_hsa005652.06015493
11Retrograde endocannabinoid signaling_Homo sapiens_hsa047231.81241264
12Serotonergic synapse_Homo sapiens_hsa047261.78844630
13Morphine addiction_Homo sapiens_hsa050321.76599532
14Type II diabetes mellitus_Homo sapiens_hsa049301.74759008
15Vibrio cholerae infection_Homo sapiens_hsa051101.72129719
16Glutamatergic synapse_Homo sapiens_hsa047241.71014262
17Cocaine addiction_Homo sapiens_hsa050301.65076050
18Circadian entrainment_Homo sapiens_hsa047131.61117985
19Nicotine addiction_Homo sapiens_hsa050331.56630110
20Synaptic vesicle cycle_Homo sapiens_hsa047211.52473634
21Sphingolipid metabolism_Homo sapiens_hsa006001.51295587
22Synthesis and degradation of ketone bodies_Homo sapiens_hsa000721.46243886
23SNARE interactions in vesicular transport_Homo sapiens_hsa041301.44319910
24Protein processing in endoplasmic reticulum_Homo sapiens_hsa041411.41968542
25Taste transduction_Homo sapiens_hsa047421.40133331
26Linoleic acid metabolism_Homo sapiens_hsa005911.38024022
27Long-term depression_Homo sapiens_hsa047301.31961555
28Dopaminergic synapse_Homo sapiens_hsa047281.30155822
29Cholinergic synapse_Homo sapiens_hsa047251.29428882
30alpha-Linolenic acid metabolism_Homo sapiens_hsa005921.25505059
31Collecting duct acid secretion_Homo sapiens_hsa049661.24930410
32Axon guidance_Homo sapiens_hsa043601.21387267
33Nitrogen metabolism_Homo sapiens_hsa009101.18261927
34Amphetamine addiction_Homo sapiens_hsa050311.16690702
35Carbohydrate digestion and absorption_Homo sapiens_hsa049731.13318005
36Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006041.13200898
37Lysosome_Homo sapiens_hsa041421.11382665
38Vasopressin-regulated water reabsorption_Homo sapiens_hsa049621.08397965
39Parkinsons disease_Homo sapiens_hsa050121.05603597
40Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006031.03462761
41Pancreatic secretion_Homo sapiens_hsa049721.03316464
42Vascular smooth muscle contraction_Homo sapiens_hsa042701.01211813
43Circadian rhythm_Homo sapiens_hsa047100.98532725
44Tryptophan metabolism_Homo sapiens_hsa003800.97443188
45Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.94530720
46Renal cell carcinoma_Homo sapiens_hsa052110.93738166
47Primary bile acid biosynthesis_Homo sapiens_hsa001200.90493922
48Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049640.90037862
49Peroxisome_Homo sapiens_hsa041460.89299825
50Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.88410920
51Long-term potentiation_Homo sapiens_hsa047200.87548169
52beta-Alanine metabolism_Homo sapiens_hsa004100.86567181
53Aldosterone synthesis and secretion_Homo sapiens_hsa049250.86145087
54Type I diabetes mellitus_Homo sapiens_hsa049400.85476841
55Renin secretion_Homo sapiens_hsa049240.85402896
56Regulation of autophagy_Homo sapiens_hsa041400.83772809
57Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.83433975
58Valine, leucine and isoleucine degradation_Homo sapiens_hsa002800.82173141
59Phosphatidylinositol signaling system_Homo sapiens_hsa040700.79797218
60Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049610.79398914
61Salivary secretion_Homo sapiens_hsa049700.79169590
62Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.75999664
63Butanoate metabolism_Homo sapiens_hsa006500.75147602
64Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049600.74946146
65Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.74720262
66Ovarian steroidogenesis_Homo sapiens_hsa049130.73691544
67Phototransduction_Homo sapiens_hsa047440.72749970
68Dorso-ventral axis formation_Homo sapiens_hsa043200.72578196
69Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042610.72444558
70cAMP signaling pathway_Homo sapiens_hsa040240.70410327
71cGMP-PKG signaling pathway_Homo sapiens_hsa040220.69372961
72Thyroid hormone synthesis_Homo sapiens_hsa049180.68766864
73Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001300.68434062
74Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010400.67858965
75Taurine and hypotaurine metabolism_Homo sapiens_hsa004300.67153051
76Folate biosynthesis_Homo sapiens_hsa007900.66305188
77N-Glycan biosynthesis_Homo sapiens_hsa005100.63852197
78Histidine metabolism_Homo sapiens_hsa003400.63374642
79Mineral absorption_Homo sapiens_hsa049780.62381067
80Sphingolipid signaling pathway_Homo sapiens_hsa040710.60409557
81Inositol phosphate metabolism_Homo sapiens_hsa005620.59984901
82Selenocompound metabolism_Homo sapiens_hsa004500.59796500
83Alcoholism_Homo sapiens_hsa050340.58900526
84Oxytocin signaling pathway_Homo sapiens_hsa049210.58899382
85Phospholipase D signaling pathway_Homo sapiens_hsa040720.58341036
86ErbB signaling pathway_Homo sapiens_hsa040120.57993847
87ABC transporters_Homo sapiens_hsa020100.56881269
88Ras signaling pathway_Homo sapiens_hsa040140.56802330
89Huntingtons disease_Homo sapiens_hsa050160.55404991
90Vitamin B6 metabolism_Homo sapiens_hsa007500.55042893
91Propanoate metabolism_Homo sapiens_hsa006400.54423185
92Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.54225729
93Choline metabolism in cancer_Homo sapiens_hsa052310.54052443
94Gastric acid secretion_Homo sapiens_hsa049710.53992045
95Glycerophospholipid metabolism_Homo sapiens_hsa005640.53484207
96Gap junction_Homo sapiens_hsa045400.53192431
97Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.51516437
98Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.50848403
99Endocytosis_Homo sapiens_hsa041440.50419374
100Alzheimers disease_Homo sapiens_hsa050100.50402489
101Bile secretion_Homo sapiens_hsa049760.48524189
102GnRH signaling pathway_Homo sapiens_hsa049120.48521049
103Estrogen signaling pathway_Homo sapiens_hsa049150.47821302
104Oxidative phosphorylation_Homo sapiens_hsa001900.47681905
105Prion diseases_Homo sapiens_hsa050200.46715761
106Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047500.45314699
107Caffeine metabolism_Homo sapiens_hsa002320.45255920
108Rheumatoid arthritis_Homo sapiens_hsa053230.45125405
109Phagosome_Homo sapiens_hsa041450.43777775
110Other glycan degradation_Homo sapiens_hsa005110.43077306
111Glycosaminoglycan degradation_Homo sapiens_hsa005310.42790991
112Tight junction_Homo sapiens_hsa045300.42228925
113Cardiac muscle contraction_Homo sapiens_hsa042600.42176872
114Olfactory transduction_Homo sapiens_hsa047400.40925305
115Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049320.40634400
116MAPK signaling pathway_Homo sapiens_hsa040100.39207694
117Calcium signaling pathway_Homo sapiens_hsa040200.37403810
118Ascorbate and aldarate metabolism_Homo sapiens_hsa000530.37339083
119Arachidonic acid metabolism_Homo sapiens_hsa005900.36324570
120Autoimmune thyroid disease_Homo sapiens_hsa053200.32930580
121Glucagon signaling pathway_Homo sapiens_hsa049220.32487965
122Steroid hormone biosynthesis_Homo sapiens_hsa001400.31419549
123Basal transcription factors_Homo sapiens_hsa030220.31255071
124Drug metabolism - cytochrome P450_Homo sapiens_hsa009820.31021787

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