ST13P15

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1DNA deamination (GO:0045006)6.95304215
2regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:00450916.68915262
3cytidine metabolic process (GO:0046087)5.65674849
4cytidine catabolic process (GO:0006216)5.65674849
5cytidine deamination (GO:0009972)5.65674849
6response to pheromone (GO:0019236)5.29539082
7tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388)4.76427972
8RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394)4.76427972
9pyrimidine ribonucleoside catabolic process (GO:0046133)4.68293758
10T cell migration (GO:0072678)4.19386690
11GTP biosynthetic process (GO:0006183)4.05888007
12negative regulation of nitric-oxide synthase activity (GO:0051001)4.03391810
13DNA demethylation (GO:0080111)3.92143071
14mitochondrial respiratory chain complex I assembly (GO:0032981)3.79550460
15NADH dehydrogenase complex assembly (GO:0010257)3.79550460
16mitochondrial respiratory chain complex I biogenesis (GO:0097031)3.79550460
17aldehyde catabolic process (GO:0046185)3.71083446
18nucleoside diphosphate phosphorylation (GO:0006165)3.70599584
19piRNA metabolic process (GO:0034587)3.67423365
20protein complex biogenesis (GO:0070271)3.63248826
21platelet dense granule organization (GO:0060155)3.50570269
22establishment of protein localization to mitochondrial membrane (GO:0090151)3.41882641
23regulation of immunoglobulin secretion (GO:0051023)3.34842973
24peptidyl-histidine modification (GO:0018202)3.34744009
25regulation of sarcomere organization (GO:0060297)3.30266360
26positive regulation of defense response to virus by host (GO:0002230)3.25902869
27adaptation of signaling pathway (GO:0023058)3.24789294
28negative regulation of potassium ion transmembrane transporter activity (GO:1901017)3.19995394
29UTP biosynthetic process (GO:0006228)3.18911761
30mitochondrial respiratory chain complex assembly (GO:0033108)3.13112746
31Arp2/3 complex-mediated actin nucleation (GO:0034314)3.12962978
32energy coupled proton transport, down electrochemical gradient (GO:0015985)3.12552609
33ATP synthesis coupled proton transport (GO:0015986)3.12552609
34regulation of tyrosine phosphorylation of Stat5 protein (GO:0042522)3.11883337
35mitochondrial ATP synthesis coupled proton transport (GO:0042776)3.09901612
36UTP metabolic process (GO:0046051)3.08503068
37mitochondrial electron transport, NADH to ubiquinone (GO:0006120)3.05340424
38zinc ion homeostasis (GO:0055069)3.05285744
39water-soluble vitamin biosynthetic process (GO:0042364)3.02400006
40negative T cell selection (GO:0043383)2.97077633
41regulation of isotype switching to IgG isotypes (GO:0048302)2.94683730
42negative regulation of transcription regulatory region DNA binding (GO:2000678)2.94025132
43regulation of B cell receptor signaling pathway (GO:0050855)2.92963188
44regulation of T-helper 1 type immune response (GO:0002825)2.92803519
45negative regulation by host of viral transcription (GO:0043922)2.92373152
46negative regulation of execution phase of apoptosis (GO:1900118)2.92027170
47chaperone-mediated protein transport (GO:0072321)2.91266827
48DNA dealkylation (GO:0035510)2.91264816
49ribonucleoprotein complex disassembly (GO:0032988)2.89321646
50positive regulation of tyrosine phosphorylation of Stat5 protein (GO:0042523)2.89286195
51negative regulation of telomere maintenance (GO:0032205)2.87402944
52actin nucleation (GO:0045010)2.83455742
53axoneme assembly (GO:0035082)2.81444065
54pantothenate metabolic process (GO:0015939)2.81388629
55positive regulation of antigen receptor-mediated signaling pathway (GO:0050857)2.78871189
56regulation of chronic inflammatory response (GO:0002676)2.78432204
57single strand break repair (GO:0000012)2.77151116
58positive regulation of alpha-beta T cell proliferation (GO:0046641)2.76294487
59negative regulation of monooxygenase activity (GO:0032769)2.76247660
60intrinsic apoptotic signaling pathway in response to oxidative stress (GO:0008631)2.76142896
61positive T cell selection (GO:0043368)2.76012922
62protein neddylation (GO:0045116)2.73472275
63sequestering of actin monomers (GO:0042989)2.72330751
64regulation of skeletal muscle contraction (GO:0014819)2.70695065
65positive regulation of uterine smooth muscle contraction (GO:0070474)2.70111694
66adenosine metabolic process (GO:0046085)2.69475904
67positive regulation of T-helper 1 type immune response (GO:0002827)2.68104332
68respiratory chain complex IV assembly (GO:0008535)2.65514356
69protein polyglutamylation (GO:0018095)2.64604852
70coenzyme A biosynthetic process (GO:0015937)2.64324234
71regulation of action potential (GO:0098900)2.63586433
72DNA methylation involved in gamete generation (GO:0043046)2.63193767
73negative regulation of oxidoreductase activity (GO:0051354)2.61579481
74forebrain morphogenesis (GO:0048853)2.58898780
75negative regulation of potassium ion transmembrane transport (GO:1901380)2.58039634
76regulation of catecholamine uptake involved in synaptic transmission (GO:0051940)2.57604200
77regulation of dopamine uptake involved in synaptic transmission (GO:0051584)2.57604200
78dopamine transport (GO:0015872)2.55993260
79negative regulation of systemic arterial blood pressure (GO:0003085)2.55316563
80positive regulation of cAMP-mediated signaling (GO:0043950)2.53620038
81guanosine-containing compound biosynthetic process (GO:1901070)2.51490214
82nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291)2.49734866
83positive regulation of interleukin-2 biosynthetic process (GO:0045086)2.49587943
84lymphocyte chemotaxis (GO:0048247)2.47788169
85positive regulation of monocyte chemotaxis (GO:0090026)2.46860959
86primary alcohol catabolic process (GO:0034310)2.44287851
87response to interferon-beta (GO:0035456)2.43951140
88proteasome assembly (GO:0043248)2.42832480
89cytochrome complex assembly (GO:0017004)2.41369846
90cell fate commitment involved in formation of primary germ layer (GO:0060795)2.38424162
91positive regulation of calcium-mediated signaling (GO:0050850)2.37521607
92electron transport chain (GO:0022900)2.34611923
93protein-cofactor linkage (GO:0018065)2.33567095
94regulation of activation of Janus kinase activity (GO:0010533)2.32000256
95respiratory electron transport chain (GO:0022904)2.31855779
96purine nucleoside triphosphate biosynthetic process (GO:0009145)2.30847766
97negative regulation of viral genome replication (GO:0045071)2.30348003
98regulation of acyl-CoA biosynthetic process (GO:0050812)2.30285155
99positive regulation of T cell mediated cytotoxicity (GO:0001916)2.29780840
100positive thymic T cell selection (GO:0045059)2.29604577

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse4.20631487
2ZNF274_21170338_ChIP-Seq_K562_Hela4.04033248
3HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse3.82372439
4E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse3.76601983
5GATA1_22025678_ChIP-Seq_K562_Human3.64630543
6IGF1R_20145208_ChIP-Seq_DFB_Human3.41973515
7GABP_17652178_ChIP-ChIP_JURKAT_Human3.41163337
8CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human3.06917219
9VDR_22108803_ChIP-Seq_LS180_Human2.90296970
10NOTCH1_21737748_ChIP-Seq_TLL_Human2.64525276
11EZH2_22144423_ChIP-Seq_EOC_Human2.64198203
12HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human2.60952620
13EST1_17652178_ChIP-ChIP_JURKAT_Human2.58538005
14GBX2_23144817_ChIP-Seq_PC3_Human2.49134660
15KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human2.41864181
16VDR_23849224_ChIP-Seq_CD4+_Human2.21314549
17TAF15_26573619_Chip-Seq_HEK293_Human2.18634396
18FUS_26573619_Chip-Seq_HEK293_Human2.17386212
19IRF1_21803131_ChIP-Seq_MONOCYTES_Human2.06028418
20NOTCH1_17114293_ChIP-ChIP_T-ALL_Human1.91062395
21IRF8_22096565_ChIP-ChIP_GC-B_Mouse1.90194103
22EWS_26573619_Chip-Seq_HEK293_Human1.88993747
23IRF8_22096565_ChIP-ChIP_GC-B_Human1.79907159
24BP1_19119308_ChIP-ChIP_Hs578T_Human1.77294902
25FLI1_27457419_Chip-Seq_LIVER_Mouse1.77104540
26SRF_21415370_ChIP-Seq_HL-1_Mouse1.73146282
27POU3F2_20337985_ChIP-ChIP_501MEL_Human1.72177900
28EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human1.71507665
29TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.67912160
30ZFP57_27257070_Chip-Seq_ESCs_Mouse1.64912756
31ELK1_19687146_ChIP-ChIP_HELA_Human1.64632710
32ELF1_17652178_ChIP-ChIP_JURKAT_Human1.64326570
33PCGF2_27294783_Chip-Seq_ESCs_Mouse1.63842006
34CTBP1_25329375_ChIP-Seq_LNCAP_Human1.63537902
35ETS1_20019798_ChIP-Seq_JURKAT_Human1.61281866
36JARID1A_20064375_ChIP-Seq_MESCs_Mouse1.60946162
37RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.60195820
38MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human1.56980879
39FOXP3_21729870_ChIP-Seq_TREG_Human1.56552374
40STAT6_20620947_ChIP-Seq_CD4_POS_T_Human1.56029740
41ER_23166858_ChIP-Seq_MCF-7_Human1.54923991
42CEBPD_23245923_ChIP-Seq_MEFs_Mouse1.46643674
43CTBP2_25329375_ChIP-Seq_LNCAP_Human1.43676336
44P300_19829295_ChIP-Seq_ESCs_Human1.43145259
45MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.42755216
46GATA3_26560356_Chip-Seq_TH2_Human1.40249180
47TP53_22573176_ChIP-Seq_HFKS_Human1.39835549
48PCGF2_27294783_Chip-Seq_NPCs_Mouse1.36818311
49GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse1.36038938
50LYL1_20887958_ChIP-Seq_HPC-7_Mouse1.29814345
51POU5F1_16153702_ChIP-ChIP_HESCs_Human1.29455685
52MYB_26560356_Chip-Seq_TH2_Human1.25029287
53FOXP3_17237761_ChIP-ChIP_TREG_Mouse1.17460481
54EZH2_27294783_Chip-Seq_NPCs_Mouse1.14603507
55AR_20517297_ChIP-Seq_VCAP_Human1.14090826
56FOXA1_27270436_Chip-Seq_PROSTATE_Human1.13682656
57FOXA1_25329375_ChIP-Seq_VCAP_Human1.13682656
58MYC_18940864_ChIP-ChIP_HL60_Human1.13143087
59HTT_18923047_ChIP-ChIP_STHdh_Human1.12058402
60TAL1_26923725_Chip-Seq_HPCs_Mouse1.12024004
61CTNNB1_24651522_ChIP-Seq_LGR5+_INTESTINAL_STEM_Human1.11370205
62CBP_20019798_ChIP-Seq_JUKART_Human1.08101926
63IRF4_20064451_ChIP-Seq_CD4+T_Mouse1.08101926
64AR_21572438_ChIP-Seq_LNCaP_Human1.07942236
65TOP2B_26459242_ChIP-Seq_MCF-7_Human1.06706281
66GATA3_21878914_ChIP-Seq_MCF-7_Human1.06478051
67FOXP2_21765815_ChIP-ChIP_NEURO2A_Mouse1.05494430
68NFE2_27457419_Chip-Seq_LIVER_Mouse1.05318434
69UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human1.05095824
70PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.03688950
71CHD1_19587682_ChIP-ChIP_MESCs_Mouse1.03079295
72IRF8_21731497_ChIP-ChIP_J774_Mouse1.02146250
73NANOG_19829295_ChIP-Seq_ESCs_Human1.00521877
74SOX2_19829295_ChIP-Seq_ESCs_Human1.00521877
75BCAT_22108803_ChIP-Seq_LS180_Human1.00311567
76PBX1_22567123_ChIP-ChIP_OVCAR3_Human0.98168014
77IRF1_19129219_ChIP-ChIP_H3396_Human0.97770117
78AUTS2_25519132_ChIP-Seq_293T-REX_Human0.97749857
79PIAS1_25552417_ChIP-Seq_VCAP_Human0.96816180
80GLI1_17442700_ChIP-ChIP_MESCs_Mouse0.96477165
81SOX9_22984422_ChIP-ChIP_TESTIS_Rat0.95422077
82FOXA1_21572438_ChIP-Seq_LNCaP_Human0.95253183
83SMAD3_21741376_ChIP-Seq_EPCs_Human0.94259338
84IKZF1_21737484_ChIP-ChIP_HCT116_Human0.93532665
85PRDM14_20953172_ChIP-Seq_ESCs_Human0.93355898
86SUZ12_27294783_Chip-Seq_NPCs_Mouse0.92363617
87HOXB4_20404135_ChIP-ChIP_EML_Mouse0.91530495
88FLI1_21867929_ChIP-Seq_TH2_Mouse0.90968772
89CRX_20693478_ChIP-Seq_RETINA_Mouse0.90695150
90JUN_21703547_ChIP-Seq_K562_Human0.90186920
91ELK1_22589737_ChIP-Seq_MCF10A_Human0.90142309
92KLF5_20875108_ChIP-Seq_MESCs_Mouse0.88930117
93CDX2_21402776_ChIP-Seq_INTESTINAL-VILLUS_Mouse0.88882962
94AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human0.87373982
95PAX6_23342162_ChIP-ChIP_BETA-FORBRAIN-LENS_Mouse0.86719386
96EBNA2_21746931_ChIP-Seq_IB4-LCL_Human0.86645470
97MYC_19829295_ChIP-Seq_ESCs_Human0.86574048
98GATA3_27048872_Chip-Seq_THYMUS_Human0.85103766
99TCF4_22108803_ChIP-Seq_LS180_Human0.84850679
100FOXH1_21741376_ChIP-Seq_EPCs_Human0.84724508

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0002102_abnormal_ear_morphology4.33671874
2MP0005671_abnormal_response_to3.21720027
3MP0002138_abnormal_hepatobiliary_system2.68232067
4MP0002837_dystrophic_cardiac_calcinosis2.61516098
5MP0008872_abnormal_physiological_respon2.56756613
6MP0009785_altered_susceptibility_to2.52241778
7MP0006072_abnormal_retinal_apoptosis2.34603270
8MP0005646_abnormal_pituitary_gland2.13548826
9MP0008995_early_reproductive_senescence2.11572097
10MP0003183_abnormal_peptide_metabolism2.03042662
11MP0000569_abnormal_digit_pigmentation1.98950892
12MP0006292_abnormal_olfactory_placode1.98750223
13MP0005377_hearing/vestibular/ear_phenot1.95247839
14MP0003878_abnormal_ear_physiology1.95247839
15MP0004145_abnormal_muscle_electrophysio1.91637072
16MP0001485_abnormal_pinna_reflex1.87378333
17MP0001984_abnormal_olfaction1.86996742
18MP0006082_CNS_inflammation1.86699165
19MP0001873_stomach_inflammation1.83279932
20MP0005645_abnormal_hypothalamus_physiol1.82802056
21MP0003786_premature_aging1.75872053
22MP0008789_abnormal_olfactory_epithelium1.72499069
23MP0002095_abnormal_skin_pigmentation1.71919634
24MP0004142_abnormal_muscle_tone1.71576241
25MP0008877_abnormal_DNA_methylation1.65670890
26MP0002876_abnormal_thyroid_physiology1.65169235
27MP0004742_abnormal_vestibular_system1.65047192
28MP0003950_abnormal_plasma_membrane1.63472712
29MP0005623_abnormal_meninges_morphology1.62694556
30MP0001542_abnormal_bone_strength1.61952778
31MP0004885_abnormal_endolymph1.58894471
32MP0001529_abnormal_vocalization1.55766642
33MP0000749_muscle_degeneration1.54166693
34MP0005174_abnormal_tail_pigmentation1.54090990
35MP0003718_maternal_effect1.52991986
36MP0005551_abnormal_eye_electrophysiolog1.43107679
37MP0002166_altered_tumor_susceptibility1.40998300
38MP0003646_muscle_fatigue1.37691061
39MP0001835_abnormal_antigen_presentation1.33040472
40MP0002148_abnormal_hypersensitivity_rea1.32295407
41MP0001800_abnormal_humoral_immune1.31504556
42MP0005075_abnormal_melanosome_morpholog1.30852606
43MP0008875_abnormal_xenobiotic_pharmacok1.26459304
44MP0005187_abnormal_penis_morphology1.24598782
45MP0000685_abnormal_immune_system1.24356010
46MP0003252_abnormal_bile_duct1.20615492
47MP0001905_abnormal_dopamine_level1.18765274
48MP0005394_taste/olfaction_phenotype1.17135299
49MP0005499_abnormal_olfactory_system1.17135299
50MP0001293_anophthalmia1.16163783
51MP0003866_abnormal_defecation1.15959822
52MP0003763_abnormal_thymus_physiology1.13468208
53MP0002163_abnormal_gland_morphology1.08404939
54MP0002254_reproductive_system_inflammat1.06170616
55MP0001764_abnormal_homeostasis1.05513352
56MP0003880_abnormal_central_pattern1.05502695
57MP0002723_abnormal_immune_serum1.05337153
58MP0009379_abnormal_foot_pigmentation1.04019311
59MP0001968_abnormal_touch/_nociception1.04003296
60MP0003938_abnormal_ear_development1.03905780
61MP0002277_abnormal_respiratory_mucosa0.99689291
62MP0002736_abnormal_nociception_after0.98759257
63MP0000015_abnormal_ear_pigmentation0.98477388
64MP0000372_irregular_coat_pigmentation0.94686811
65MP0001486_abnormal_startle_reflex0.94612117
66MP0005389_reproductive_system_phenotype0.94501184
67MP0002638_abnormal_pupillary_reflex0.92734528
68MP0001919_abnormal_reproductive_system0.92087720
69MP0005253_abnormal_eye_physiology0.91038260
70MP0002006_tumorigenesis0.90659085
71MP0003045_fibrosis0.87621880
72MP0004883_abnormal_blood_vessel0.86917791
73MP0004215_abnormal_myocardial_fiber0.84049694
74MP0005166_decreased_susceptibility_to0.83457534
75MP0005410_abnormal_fertilization0.82958008
76MP0002420_abnormal_adaptive_immunity0.80763044
77MP0003693_abnormal_embryo_hatching0.80717381
78MP0005084_abnormal_gallbladder_morpholo0.80621750
79MP0000230_abnormal_systemic_arterial0.79219643
80MP0000631_abnormal_neuroendocrine_gland0.78807014
81MP0005025_abnormal_response_to0.78553945
82MP0002751_abnormal_autonomic_nervous0.78404558
83MP0005636_abnormal_mineral_homeostasis0.78397778
84MP0003656_abnormal_erythrocyte_physiolo0.78289484
85MP0003724_increased_susceptibility_to0.77962943
86MP0001819_abnormal_immune_cell0.77811179
87MP0000026_abnormal_inner_ear0.77549563
88MP0000427_abnormal_hair_cycle0.76940294
89MP0002938_white_spotting0.75854683
90MP0002405_respiratory_system_inflammati0.75336750
91MP0005386_behavior/neurological_phenoty0.75002043
92MP0004924_abnormal_behavior0.75002043
93MP0002234_abnormal_pharynx_morphology0.74199579
94MP0005670_abnormal_white_adipose0.73036163
95MP0002272_abnormal_nervous_system0.72909415
96MP0002160_abnormal_reproductive_system0.72012587
97MP0009765_abnormal_xenobiotic_induced0.71867619
98MP0002452_abnormal_antigen_presenting0.71626043
99MP0005000_abnormal_immune_tolerance0.70252642
100MP0000639_abnormal_adrenal_gland0.69458270

Predicted human phenotypes

RankGene SetZ-score
1Aplastic anemia (HP:0001915)4.23189330
2Renal cortical cysts (HP:0000803)3.74501766
3Calf muscle hypertrophy (HP:0008981)3.60599087
4Hypoproteinemia (HP:0003075)3.43381499
5T lymphocytopenia (HP:0005403)3.33639098
6Congenital stationary night blindness (HP:0007642)3.28385867
7Subaortic stenosis (HP:0001682)3.26405900
8Abnormality of the left ventricular outflow tract (HP:0011103)3.26405900
9Pancreatic fibrosis (HP:0100732)3.23022338
10Pancreatic cysts (HP:0001737)3.16714676
11Abolished electroretinogram (ERG) (HP:0000550)3.13596149
12Abnormal albumin level (HP:0012116)3.12239907
13Hypoalbuminemia (HP:0003073)3.12239907
14Muscle hypertrophy of the lower extremities (HP:0008968)3.10741663
15Absent rod-and cone-mediated responses on ERG (HP:0007688)3.09929886
16Neonatal respiratory distress (HP:0002643)3.01271059
17Stomatitis (HP:0010280)2.93942494
18Abnormality of T cell number (HP:0011839)2.91832750
19Abnormality of placental membranes (HP:0011409)2.85620480
20Amniotic constriction ring (HP:0009775)2.85620480
21True hermaphroditism (HP:0010459)2.85373299
22Abnormality of glycolysis (HP:0004366)2.83912860
23Medial flaring of the eyebrow (HP:0010747)2.82645072
24Hypoplasia of the thymus (HP:0000778)2.78922632
25Renal Fanconi syndrome (HP:0001994)2.78026415
26Type II lissencephaly (HP:0007260)2.76383941
27Constricted visual fields (HP:0001133)2.72061693
28Abnormality of midbrain morphology (HP:0002418)2.71591982
29Molar tooth sign on MRI (HP:0002419)2.71591982
30Increased hepatocellular lipid droplets (HP:0006565)2.71463398
31Prostate neoplasm (HP:0100787)2.71396804
32Abnormality of the renal cortex (HP:0011035)2.70148996
33Abnormal rod and cone electroretinograms (HP:0008323)2.69677290
34Abnormality of macular pigmentation (HP:0008002)2.68259579
35Severe combined immunodeficiency (HP:0004430)2.67152450
363-Methylglutaconic aciduria (HP:0003535)2.65322885
37Oral leukoplakia (HP:0002745)2.60630795
38Mitochondrial inheritance (HP:0001427)2.60002995
39Abnormality of the prostate (HP:0008775)2.59822965
40Lipid accumulation in hepatocytes (HP:0006561)2.56532779
41Mesangial abnormality (HP:0001966)2.49524340
42Hepatocellular necrosis (HP:0001404)2.48915493
43Abnormal gallbladder physiology (HP:0012438)2.35115866
44Cholecystitis (HP:0001082)2.35115866
45Optic disc pallor (HP:0000543)2.28239216
46Hypothermia (HP:0002045)2.26977243
47Decreased electroretinogram (ERG) amplitude (HP:0000654)2.24845896
48Acute necrotizing encephalopathy (HP:0006965)2.24740248
49Abnormal activity of mitochondrial respiratory chain (HP:0011922)2.24184207
50Decreased activity of mitochondrial respiratory chain (HP:0008972)2.24184207
51Tubular atrophy (HP:0000092)2.23664985
52Elevated erythrocyte sedimentation rate (HP:0003565)2.22298732
53Thoracolumbar scoliosis (HP:0002944)2.22240892
54Increased CSF lactate (HP:0002490)2.22213114
55Chronic hepatic failure (HP:0100626)2.20780402
56Aplasia/Hypoplasia involving the musculature (HP:0001460)2.19322767
57Attenuation of retinal blood vessels (HP:0007843)2.18368381
58Abnormality of alanine metabolism (HP:0010916)2.17745601
59Hyperalaninemia (HP:0003348)2.17745601
60Abnormality of pyruvate family amino acid metabolism (HP:0010915)2.17745601
61Exertional dyspnea (HP:0002875)2.17217531
62Hepatic necrosis (HP:0002605)2.16324326
63Short tibia (HP:0005736)2.14971856
64Pendular nystagmus (HP:0012043)2.13487484
65Symphalangism affecting the phalanges of the hand (HP:0009773)2.13033247
66Stomach cancer (HP:0012126)2.12461317
67Progressive inability to walk (HP:0002505)2.09661587
68Impaired proprioception (HP:0010831)2.09391288
69Generalized aminoaciduria (HP:0002909)2.08411534
70Lactic acidosis (HP:0003128)2.07922941
71Aplasia/Hypoplasia of the tibia (HP:0005772)2.07761474
72Aplasia/hypoplasia of the uterus (HP:0008684)2.04210841
73Palpebral edema (HP:0100540)2.02395750
74Metaphyseal dysplasia (HP:0100255)2.02336854
75J-shaped sella turcica (HP:0002680)2.01935084
76Congenital primary aphakia (HP:0007707)2.00355729
77Progressive macrocephaly (HP:0004481)1.99996235
78Facial hemangioma (HP:0000329)1.96465718
79Increased intramyocellular lipid droplets (HP:0012240)1.96057769
80Cystic liver disease (HP:0006706)1.95610919
81Thyroiditis (HP:0100646)1.95464194
82Abnormality of T cells (HP:0002843)1.95379109
83IgG deficiency (HP:0004315)1.93600375
84Inability to walk (HP:0002540)1.92599246
85Exercise-induced muscle cramps (HP:0003710)1.92093000
86Gait imbalance (HP:0002141)1.91915506
87Nephrogenic diabetes insipidus (HP:0009806)1.91410804
88Nephronophthisis (HP:0000090)1.91121320
89Increased serum lactate (HP:0002151)1.90302659
90Reduced antithrombin III activity (HP:0001976)1.89573357
91Colon cancer (HP:0003003)1.86920040
92Abnormality of the middle phalanges of the toes (HP:0010183)1.85348681
93Hyperglycinemia (HP:0002154)1.84801412
94Abnormal mitochondria in muscle tissue (HP:0008316)1.84420338
95Abnormal drinking behavior (HP:0030082)1.84316156
96Polydipsia (HP:0001959)1.84316156
97Sclerocornea (HP:0000647)1.84193416
98Failure to thrive in infancy (HP:0001531)1.83718902
99Chronic diarrhea (HP:0002028)1.80976083
100Aplasia/Hypoplasia of the tongue (HP:0010295)1.78592862

Predicted kinase interactions (KEA)

RankGene SetZ-score
1MAP4K26.08614256
2TXK4.21622244
3BMPR1B3.09123964
4MAPKAPK52.42678252
5CDK82.40130614
6TAOK32.32568686
7TLK12.22870249
8PKN22.12210026
9VRK12.11051217
10VRK22.08746929
11FLT32.04994095
12BCKDK2.00190392
13NUAK11.97232574
14MAP4K11.81809383
15FRK1.77930041
16WNK41.75146699
17DAPK21.73203854
18TAF11.72907704
19TGFBR11.71829867
20ADRBK21.51543155
21ZAK1.50259027
22ITK1.43230167
23TNK21.42724875
24BLK1.36078900
25MKNK11.33794811
26EIF2AK31.30634685
27GRK51.25217791
28TEC1.23121667
29PRKD31.14104140
30GRK11.12269863
31GRK71.05571295
32MOS1.02125506
33MUSK0.98742217
34GRK60.97285158
35PIK3CA0.93169533
36STK160.91778355
37PLK20.91112643
38KDR0.90732879
39RPS6KA50.90625804
40PLK30.89415229
41DAPK10.89080380
42EIF2AK10.85615314
43NEK10.85604258
44MAP3K70.84514067
45PAK60.83306441
46NTRK20.83080564
47PAK30.82938486
48TIE10.81871726
49SYK0.81371983
50WNK30.78946130
51RPS6KA40.78277331
52DYRK20.77053643
53INSRR0.76961567
54CDK90.74699752
55IKBKE0.73434981
56PRKCQ0.72752248
57IKBKB0.68225646
58MAP3K40.67394653
59MAP2K70.64863280
60MST40.64821162
61STK390.64729544
62PDK20.64080710
63EIF2AK20.62873993
64STK240.62592569
65RIPK40.62551439
66RPS6KA60.60738042
67CAMKK20.59791356
68STK100.58559554
69OXSR10.57325149
70ADRBK10.56885195
71IRAK40.56586196
72DAPK30.54811335
73DYRK30.52413966
74ZAP700.51005930
75RPS6KA20.48274840
76CDC70.47346657
77BRD40.46852806
78TRIM280.46677219
79CAMK2D0.46252370
80MAPK130.44389655
81NME10.44268501
82CASK0.42817276
83RPS6KL10.41789632
84RPS6KC10.41789632
85PRKCE0.41277269
86LCK0.41163905
87PIM10.40870771
88NTRK30.39959849
89ARAF0.39349897
90IGF1R0.36863369
91LYN0.36315511
92BTK0.35822969
93CSNK1A10.35503511
94TNIK0.35472962
95PIK3CG0.34018635
96CSNK1G30.33171273
97CDK190.31809535
98JAK20.31208987
99KIT0.31137557
100FGFR10.30283273

Predicted pathways (KEGG)

RankGene SetZ-score
1Primary immunodeficiency_Homo sapiens_hsa053403.75904289
2Proteasome_Homo sapiens_hsa030503.73731854
3Oxidative phosphorylation_Homo sapiens_hsa001903.08778922
4Parkinsons disease_Homo sapiens_hsa050122.91977890
5Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005632.70800938
6Basal transcription factors_Homo sapiens_hsa030222.62780902
7Selenocompound metabolism_Homo sapiens_hsa004502.47776145
8Protein export_Homo sapiens_hsa030602.36379491
9Antigen processing and presentation_Homo sapiens_hsa046122.17388593
10Ribosome_Homo sapiens_hsa030102.12546420
11Synthesis and degradation of ketone bodies_Homo sapiens_hsa000722.01077895
12Autoimmune thyroid disease_Homo sapiens_hsa053201.92339691
13Nitrogen metabolism_Homo sapiens_hsa009101.86339655
14Phototransduction_Homo sapiens_hsa047441.84743105
15Cardiac muscle contraction_Homo sapiens_hsa042601.79497080
16Allograft rejection_Homo sapiens_hsa053301.73471668
17Pantothenate and CoA biosynthesis_Homo sapiens_hsa007701.69389017
18Nucleotide excision repair_Homo sapiens_hsa034201.67032277
19Hematopoietic cell lineage_Homo sapiens_hsa046401.66274403
20Graft-versus-host disease_Homo sapiens_hsa053321.65407712
21Huntingtons disease_Homo sapiens_hsa050161.64136014
22RNA polymerase_Homo sapiens_hsa030201.63478916
23Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046501.60202329
24Alzheimers disease_Homo sapiens_hsa050101.56154905
25T cell receptor signaling pathway_Homo sapiens_hsa046601.54465108
26Cytosolic DNA-sensing pathway_Homo sapiens_hsa046231.52612388
27Homologous recombination_Homo sapiens_hsa034401.50760972
28Linoleic acid metabolism_Homo sapiens_hsa005911.49487694
29Propanoate metabolism_Homo sapiens_hsa006401.47982362
30Butanoate metabolism_Homo sapiens_hsa006501.44711963
31RNA degradation_Homo sapiens_hsa030181.39907659
32Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049321.39011251
33Asthma_Homo sapiens_hsa053101.35913956
34Glycine, serine and threonine metabolism_Homo sapiens_hsa002601.34230857
35alpha-Linolenic acid metabolism_Homo sapiens_hsa005921.27672608
36Intestinal immune network for IgA production_Homo sapiens_hsa046721.26555673
37Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030081.20672315
38Neuroactive ligand-receptor interaction_Homo sapiens_hsa040801.19124379
39Peroxisome_Homo sapiens_hsa041461.16976863
40Valine, leucine and isoleucine degradation_Homo sapiens_hsa002801.14719176
41Rheumatoid arthritis_Homo sapiens_hsa053231.02906437
42Cytokine-cytokine receptor interaction_Homo sapiens_hsa040601.00156703
43Purine metabolism_Homo sapiens_hsa002300.97536684
44Ether lipid metabolism_Homo sapiens_hsa005650.94471621
45Caffeine metabolism_Homo sapiens_hsa002320.93067084
46Cysteine and methionine metabolism_Homo sapiens_hsa002700.92875322
47Inflammatory bowel disease (IBD)_Homo sapiens_hsa053210.90321017
48Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.87444517
49Salivary secretion_Homo sapiens_hsa049700.86926964
50Taste transduction_Homo sapiens_hsa047420.83522758
51Fanconi anemia pathway_Homo sapiens_hsa034600.81347799
52NF-kappa B signaling pathway_Homo sapiens_hsa040640.77647439
53Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.76829638
54Retinol metabolism_Homo sapiens_hsa008300.75694127
55Type I diabetes mellitus_Homo sapiens_hsa049400.75144540
56Pyrimidine metabolism_Homo sapiens_hsa002400.72808254
57Mismatch repair_Homo sapiens_hsa034300.71057472
58Pyruvate metabolism_Homo sapiens_hsa006200.68668209
59Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.67053077
60Spliceosome_Homo sapiens_hsa030400.64689155
61Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.63484685
62One carbon pool by folate_Homo sapiens_hsa006700.62871894
63Arachidonic acid metabolism_Homo sapiens_hsa005900.60200211
64Systemic lupus erythematosus_Homo sapiens_hsa053220.60121356
65Steroid hormone biosynthesis_Homo sapiens_hsa001400.59808505
66Ascorbate and aldarate metabolism_Homo sapiens_hsa000530.58732413
67Pentose and glucuronate interconversions_Homo sapiens_hsa000400.58546380
68Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.58057003
69Tryptophan metabolism_Homo sapiens_hsa003800.57896250
70Steroid biosynthesis_Homo sapiens_hsa001000.56669536
71Chemical carcinogenesis_Homo sapiens_hsa052040.56269699
72Ovarian steroidogenesis_Homo sapiens_hsa049130.55295518
73Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.54882466
74Primary bile acid biosynthesis_Homo sapiens_hsa001200.53320567
75Olfactory transduction_Homo sapiens_hsa047400.52680659
76Metabolic pathways_Homo sapiens_hsa011000.52588439
77Regulation of autophagy_Homo sapiens_hsa041400.51849303
78DNA replication_Homo sapiens_hsa030300.51771816
79Measles_Homo sapiens_hsa051620.51320066
80Dorso-ventral axis formation_Homo sapiens_hsa043200.47552022
81Maturity onset diabetes of the young_Homo sapiens_hsa049500.47269201
82NOD-like receptor signaling pathway_Homo sapiens_hsa046210.46121818
83Drug metabolism - cytochrome P450_Homo sapiens_hsa009820.45661104
84Jak-STAT signaling pathway_Homo sapiens_hsa046300.45523342
85beta-Alanine metabolism_Homo sapiens_hsa004100.40887344
86Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.38939440
87RNA transport_Homo sapiens_hsa030130.37767727
88Transcriptional misregulation in cancer_Homo sapiens_hsa052020.34291266
89Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009700.32059905
90Serotonergic synapse_Homo sapiens_hsa047260.30842384
91Renin secretion_Homo sapiens_hsa049240.29290481
92Glycerolipid metabolism_Homo sapiens_hsa005610.28049862
93Circadian entrainment_Homo sapiens_hsa047130.26014991
94Fat digestion and absorption_Homo sapiens_hsa049750.24871283
95Starch and sucrose metabolism_Homo sapiens_hsa005000.23918456
96Basal cell carcinoma_Homo sapiens_hsa052170.22711792
97Fatty acid elongation_Homo sapiens_hsa000620.22005724
98Malaria_Homo sapiens_hsa051440.21377375
99Insulin secretion_Homo sapiens_hsa049110.20903405
100Nicotine addiction_Homo sapiens_hsa050330.20803866

Most similar genes based on co-expression Upload to Enrichr

Tissue Expression Export image »

Cell Line Expression Export image »