ST13

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: The protein encoded by this gene is an adaptor protein that mediates the association of the heat shock proteins HSP70 and HSP90. This protein has been shown to be involved in the assembly process of glucocorticoid receptor, which requires the assistance of multiple molecular chaperones. The expression of this gene is reported to be downregulated in colorectal carcinoma tissue suggesting that it is a candidate tumor suppressor gene. Alternative splicing results in multiple transcript variants encoding different isoforms. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1cullin deneddylation (GO:0010388)5.02362529
2IMP biosynthetic process (GO:0006188)4.64097739
3protein deneddylation (GO:0000338)4.53292506
4purine nucleobase biosynthetic process (GO:0009113)4.20371596
5nuclear pore organization (GO:0006999)4.11719589
6nucleobase biosynthetic process (GO:0046112)3.90460202
7maturation of 5.8S rRNA (GO:0000460)3.81255697
8IMP metabolic process (GO:0046040)3.80950098
9negative regulation of dendrite morphogenesis (GO:0050774)3.79438678
10establishment of integrated proviral latency (GO:0075713)3.76008062
11inositol phosphate catabolic process (GO:0071545)3.71676558
12nuclear pore complex assembly (GO:0051292)3.65997262
13CENP-A containing nucleosome assembly (GO:0034080)3.65054255
14DNA ligation (GO:0006266)3.64305688
15DNA double-strand break processing (GO:0000729)3.60878769
16chromatin remodeling at centromere (GO:0031055)3.58120363
17RNA-dependent DNA replication (GO:0006278)3.52813516
18DNA unwinding involved in DNA replication (GO:0006268)3.46519702
19viral mRNA export from host cell nucleus (GO:0046784)3.37732415
20DNA replication checkpoint (GO:0000076)3.34473710
21deoxyribose phosphate biosynthetic process (GO:0046385)3.34072555
222-deoxyribonucleotide biosynthetic process (GO:0009265)3.34072555
23paraxial mesoderm development (GO:0048339)3.34038342
24DNA replication initiation (GO:0006270)3.30900700
25regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:00450913.29540752
26telomere maintenance via recombination (GO:0000722)3.27714707
27deoxyribonucleotide biosynthetic process (GO:0009263)3.27510024
28proteasome assembly (GO:0043248)3.27339138
29ribosome assembly (GO:0042255)3.23405297
30mitotic sister chromatid cohesion (GO:0007064)3.20663912
31protein-cofactor linkage (GO:0018065)3.19349505
32COPI coating of Golgi vesicle (GO:0048205)3.18379268
33Golgi transport vesicle coating (GO:0048200)3.18379268
34ribosome biogenesis (GO:0042254)3.18051282
35ribosomal large subunit biogenesis (GO:0042273)3.14140965
36kinetochore organization (GO:0051383)3.11795141
37regulation of translational fidelity (GO:0006450)3.11515157
38DNA strand elongation involved in DNA replication (GO:0006271)3.10136822
39mitotic recombination (GO:0006312)3.09346821
40telomere maintenance via semi-conservative replication (GO:0032201)3.09188556
41mitotic metaphase plate congression (GO:0007080)3.08009845
42protein complex localization (GO:0031503)3.07444278
437-methylguanosine mRNA capping (GO:0006370)3.07220992
44cellular protein complex localization (GO:0034629)3.04947291
45mitotic chromosome condensation (GO:0007076)3.04435924
467-methylguanosine RNA capping (GO:0009452)3.01876162
47RNA capping (GO:0036260)3.01876162
48L-serine metabolic process (GO:0006563)2.99790404
49establishment of chromosome localization (GO:0051303)2.95708172
50pore complex assembly (GO:0046931)2.95080451
51DNA strand elongation (GO:0022616)2.94342409
52transcription-coupled nucleotide-excision repair (GO:0006283)2.94185423
53regulation of mitotic cell cycle spindle assembly checkpoint (GO:0090266)2.93692300
54regulation of mitotic spindle checkpoint (GO:1903504)2.93692300
55postreplication repair (GO:0006301)2.93632160
56positive regulation of mitotic sister chromatid separation (GO:1901970)2.91684967
57positive regulation of mitotic metaphase/anaphase transition (GO:0045842)2.91684967
58positive regulation of metaphase/anaphase transition of cell cycle (GO:1902101)2.91684967
59regulation of RNA export from nucleus (GO:0046831)2.91368608
60regulation of protein heterodimerization activity (GO:0043497)2.90098430
61glucocorticoid receptor signaling pathway (GO:0042921)2.88752146
62negative regulation of intracellular estrogen receptor signaling pathway (GO:0033147)2.88718075
63glomerulus development (GO:0032835)2.88133190
64regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051439)2.87196952
65viral protein processing (GO:0019082)2.86989781
66negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436)2.86234298
67positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051437)2.84123914
68inositol phosphate dephosphorylation (GO:0046855)2.83821722
69phosphorylated carbohydrate dephosphorylation (GO:0046838)2.83821722
70transcription initiation from RNA polymerase I promoter (GO:0006361)2.83422062
71DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest (GO:002.81309515
72positive regulation of mitochondrial fission (GO:0090141)2.80157652
73meiotic chromosome segregation (GO:0045132)2.80103368
74signal transduction involved in mitotic DNA damage checkpoint (GO:1902402)2.78207018
75signal transduction involved in mitotic cell cycle checkpoint (GO:0072413)2.78207018
76signal transduction involved in mitotic DNA integrity checkpoint (GO:1902403)2.78207018
77protein neddylation (GO:0045116)2.75708129
78nucleobase-containing small molecule interconversion (GO:0015949)2.75600748
79transcription from RNA polymerase I promoter (GO:0006360)2.75460307
80intracellular signal transduction involved in G1 DNA damage checkpoint (GO:1902400)2.75352867
81signal transduction involved in mitotic G1 DNA damage checkpoint (GO:0072431)2.75352867
82nucleotide-excision repair, DNA gap filling (GO:0006297)2.74124697
83negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator (GO:1902254)2.73262964
84G1/S transition of mitotic cell cycle (GO:0000082)2.72657420
85cell cycle G1/S phase transition (GO:0044843)2.72657420
86oxidative phosphorylation (GO:0006119)2.72159377
87somatic diversification of immune receptors via somatic mutation (GO:0002566)2.71950932
88somatic hypermutation of immunoglobulin genes (GO:0016446)2.71950932
89negative regulation of signal transduction by p53 class mediator (GO:1901797)2.71191011
90tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388)2.69338590
91RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394)2.69338590
92DNA damage response, detection of DNA damage (GO:0042769)2.67262129
93anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process (GO:02.66965222
94signal transduction involved in cell cycle checkpoint (GO:0072395)2.66862751
95mRNA export from nucleus (GO:0006406)2.66451968
96histone exchange (GO:0043486)2.66263967
97signal transduction involved in DNA integrity checkpoint (GO:0072401)2.65587829
98signal transduction involved in DNA damage checkpoint (GO:0072422)2.65587829
99negative regulation of phagocytosis (GO:0050765)2.65437755
100kinetochore assembly (GO:0051382)2.64731148
101DNA replication-independent nucleosome organization (GO:0034724)2.64049460
102DNA replication-independent nucleosome assembly (GO:0006336)2.64049460
103negative regulation of DNA repair (GO:0045738)2.62461344
104DNA catabolic process, exonucleolytic (GO:0000738)2.62030710
105telomere maintenance (GO:0000723)2.61760178
106rRNA modification (GO:0000154)2.61371582
107metaphase plate congression (GO:0051310)2.60816362
108attachment of spindle microtubules to kinetochore (GO:0008608)2.58520952
109protein K11-linked ubiquitination (GO:0070979)2.58371387
110telomere organization (GO:0032200)2.57935395
111formation of translation preinitiation complex (GO:0001731)2.57614177
112replication fork processing (GO:0031297)2.56726761
113establishment of viral latency (GO:0019043)2.56651135
114rRNA methylation (GO:0031167)2.56466297
115RNA export from nucleus (GO:0006405)2.56421728
116ribosomal small subunit assembly (GO:0000028)2.56402207
117regulation of translational initiation (GO:0006446)2.56040933
118regulation of mitotic spindle organization (GO:0060236)2.53932701
119hyperosmotic salinity response (GO:0042538)2.52336965
120translational initiation (GO:0006413)2.51298037
121DNA synthesis involved in DNA repair (GO:0000731)2.47670710
122tRNA aminoacylation for protein translation (GO:0006418)2.44628527
123serine family amino acid biosynthetic process (GO:0009070)2.44342776
124negative regulation of potassium ion transmembrane transporter activity (GO:1901017)2.44039653
125negative regulation of potassium ion transmembrane transport (GO:1901380)2.41503862
126COPII vesicle coating (GO:0048208)2.41079245
127protein localization to kinetochore (GO:0034501)2.40998382
128nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184)2.40154190
129histone H2B ubiquitination (GO:0033523)2.36872619
130non-recombinational repair (GO:0000726)2.36637083
131double-strand break repair via nonhomologous end joining (GO:0006303)2.36637083
132DNA topological change (GO:0006265)2.35681366
133protein localization to chromosome, centromeric region (GO:0071459)2.35359378
134translational termination (GO:0006415)2.35325422
135tricarboxylic acid cycle (GO:0006099)2.34774540
136cellular hyperosmotic response (GO:0071474)2.34717893
137tRNA aminoacylation (GO:0043039)2.33354223
138amino acid activation (GO:0043038)2.33354223
139ribonucleoprotein complex disassembly (GO:0032988)2.33259066
140heterochromatin organization (GO:0070828)2.32992701
141ribonucleoprotein complex biogenesis (GO:0022613)2.32775346
142spliceosomal tri-snRNP complex assembly (GO:0000244)2.32650478
143ribosomal small subunit biogenesis (GO:0042274)2.31510659
144regulation of nucleobase-containing compound transport (GO:0032239)2.31397044
145regulation of sister chromatid cohesion (GO:0007063)2.29795608
146mitotic nuclear envelope disassembly (GO:0007077)2.28391264
147peptidyl-lysine dimethylation (GO:0018027)2.27612567
148maturation of SSU-rRNA (GO:0030490)2.26976428
149viral transcription (GO:0019083)2.26264192
150sister chromatid segregation (GO:0000819)2.25301451
151notochord development (GO:0030903)2.22543118
152mitotic sister chromatid segregation (GO:0000070)2.21873409
153ATP-dependent chromatin remodeling (GO:0043044)2.20990855
154SRP-dependent cotranslational protein targeting to membrane (GO:0006614)2.20978909
155regulation of spindle organization (GO:0090224)2.20846608
156folic acid-containing compound biosynthetic process (GO:0009396)2.20799948
157protein-DNA complex disassembly (GO:0032986)2.20312045
158nucleosome disassembly (GO:0006337)2.20312045
159regulation of acetyl-CoA biosynthetic process from pyruvate (GO:0010510)2.20140406
160synapsis (GO:0007129)2.18319165
161cotranslational protein targeting to membrane (GO:0006613)2.18276226
162nuclear envelope disassembly (GO:0051081)2.18135037
163membrane disassembly (GO:0030397)2.18135037
164regulation of cofactor metabolic process (GO:0051193)2.17453126
165regulation of coenzyme metabolic process (GO:0051196)2.17453126
166translational elongation (GO:0006414)2.16701844
167negative regulation of mRNA splicing, via spliceosome (GO:0048025)2.15649036
168protein targeting to ER (GO:0045047)2.15153831
169maintenance of protein localization in endoplasmic reticulum (GO:0035437)2.15071228
170proline biosynthetic process (GO:0006561)2.13816639
171establishment of protein localization to endoplasmic reticulum (GO:0072599)2.12222828
172glutamine metabolic process (GO:0006541)2.11289999
173RNA localization (GO:0006403)2.08666917
174retrograde vesicle-mediated transport, Golgi to ER (GO:0006890)2.06770611
175chaperone-mediated protein complex assembly (GO:0051131)2.05813663
176regulation of attachment of spindle microtubules to kinetochore (GO:0051988)2.05053204
177protein localization to endoplasmic reticulum (GO:0070972)2.04293808
178negative regulation of translational initiation (GO:0045947)2.03727672
179protein export from nucleus (GO:0006611)2.03254283
180regulation of chromosome segregation (GO:0051983)2.02676864
181mitotic spindle checkpoint (GO:0071174)2.01937704
182regulation of centriole replication (GO:0046599)2.01678096

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1E2F7_22180533_ChIP-Seq_HELA_Human7.67499678
2RBPJ_22232070_ChIP-Seq_NCS_Mouse4.20531819
3KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human4.16610187
4E2F4_17652178_ChIP-ChIP_JURKAT_Human2.95274219
5* MYC_18555785_ChIP-Seq_MESCs_Mouse2.89119675
6ELF1_17652178_ChIP-ChIP_JURKAT_Human2.85958831
7* EST1_17652178_ChIP-ChIP_JURKAT_Human2.85245017
8SALL1_21062744_ChIP-ChIP_HESCs_Human2.82264192
9ELK1_19687146_ChIP-ChIP_HELA_Human2.73963993
10GABP_17652178_ChIP-ChIP_JURKAT_Human2.63977958
11HCFC1_20581084_ChIP-Seq_MESCs_Mouse2.53438440
12* CREB1_15753290_ChIP-ChIP_HEK293T_Human2.52037769
13* JARID1A_20064375_ChIP-Seq_MESCs_Mouse2.51667954
14PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse2.51042663
15* KDM5B_21448134_ChIP-Seq_MESCs_Mouse2.48912095
16FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human2.37437943
17* MYC_19030024_ChIP-ChIP_MESCs_Mouse2.36849380
18NOTCH1_17114293_ChIP-ChIP_T-ALL_Human2.33068117
19YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse2.27098178
20HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human2.23689186
21* CLOCK_20551151_ChIP-Seq_293T_Human2.18782057
22* NELFA_20434984_ChIP-Seq_ESCs_Mouse2.18513867
23CHD1_19587682_ChIP-ChIP_MESCs_Mouse2.14924608
24SRF_21415370_ChIP-Seq_HL-1_Mouse2.08648061
25WT1_19549856_ChIP-ChIP_CCG9911_Human2.02070685
26EGR1_19374776_ChIP-ChIP_THP-1_Human2.01999802
27HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse1.97855984
28* FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse1.96917354
29MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse1.95557377
30THAP11_20581084_ChIP-Seq_MESCs_Mouse1.95212508
31MYBL2_22936984_ChIP-ChIP_MESCs_Mouse1.93527827
32MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.86732341
33* MYC_18358816_ChIP-ChIP_MESCs_Mouse1.86641645
34E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse1.86333893
35CREM_20920259_ChIP-Seq_GC1-SPG_Mouse1.84429834
36ZNF263_19887448_ChIP-Seq_K562_Human1.83422647
37* VDR_23849224_ChIP-Seq_CD4+_Human1.82943279
38* E2F1_18555785_ChIP-Seq_MESCs_Mouse1.82494364
39FOXP3_21729870_ChIP-Seq_TREG_Human1.79680823
40CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat1.79292275
41ETS1_20019798_ChIP-Seq_JURKAT_Human1.78491165
42AR_21909140_ChIP-Seq_LNCAP_Human1.76623290
43HOXB4_20404135_ChIP-ChIP_EML_Mouse1.75156569
44PDX1_19855005_ChIP-ChIP_MIN6_Mouse1.74998565
45TP63_19390658_ChIP-ChIP_HaCaT_Human1.74352480
46DCP1A_22483619_ChIP-Seq_HELA_Human1.71649156
47NANOG_18700969_ChIP-ChIP_MESCs_Mouse1.68143863
48CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human1.67913736
49PADI4_21655091_ChIP-ChIP_MCF-7_Human1.67637885
50POU5F1_18555785_ChIP-Seq_MESCs_Mouse1.64625084
51NANOG_21062744_ChIP-ChIP_HESCs_Human1.61301787
52PRDM5_23873026_ChIP-Seq_MEFs_Mouse1.60299887
53ZFP42_18358816_ChIP-ChIP_MESCs_Mouse1.60251175
54POU5F1_16153702_ChIP-ChIP_HESCs_Human1.59590133
55POU5F1_18358816_ChIP-ChIP_MESCs_Mouse1.57728965
56EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse1.57474481
57POU3F2_20337985_ChIP-ChIP_501MEL_Human1.56754916
58SALL4_18804426_ChIP-ChIP_MESCs_Mouse1.54555107
59* MYC_19079543_ChIP-ChIP_MESCs_Mouse1.53980520
60* MYCN_18555785_ChIP-Seq_MESCs_Mouse1.53720966
61E2F1_21310950_ChIP-Seq_MCF-7_Human1.52609969
62EWS_26573619_Chip-Seq_HEK293_Human1.50445896
63TCF3_18467660_ChIP-ChIP_MESCs_Mouse1.50224816
64FLI1_27457419_Chip-Seq_LIVER_Mouse1.48602474
65YY1_21170310_ChIP-Seq_MESCs_Mouse1.47703297
66SOX2_18555785_ChIP-Seq_MESCs_Mouse1.43210738
67FUS_26573619_Chip-Seq_HEK293_Human1.42005881
68* KLF4_18555785_ChIP-Seq_MESCs_Mouse1.41420549
69TRIM28_19339689_ChIP-ChIP_MESCs_Mouse1.39101847
70KLF5_18264089_ChIP-ChIP_MESCs_Mouse1.33478840
71KLF4_18264089_ChIP-ChIP_MESCs_Mouse1.33478840
72KLF2_18264089_ChIP-ChIP_MESCs_Mouse1.33478840
73NACC1_18358816_ChIP-ChIP_MESCs_Mouse1.32923637
74* CHD1_26751641_Chip-Seq_LNCaP_Human1.32845419
75* GABP_19822575_ChIP-Seq_HepG2_Human1.31049891
76ESR1_17901129_ChIP-ChIP_LIVER_Mouse1.30873671
77TTF2_22483619_ChIP-Seq_HELA_Human1.28418520
78CNOT3_19339689_ChIP-ChIP_MESCs_Mouse1.25545945
79* TAF7L_23326641_ChIP-Seq_C3H10T1-2_Mouse1.24052679
80NANOG_16153702_ChIP-ChIP_HESCs_Human1.21040900
81ESRRB_18555785_ChIP-Seq_MESCs_Mouse1.20732200
82NANOG_18555785_ChIP-Seq_MESCs_Mouse1.20322559
83PCGF2_27294783_Chip-Seq_ESCs_Mouse1.19416887
84NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse1.18532764
85HOXD13_18407260_ChIP-ChIP_DEVELOPING-LIMBS_Mouse1.18331536
86CREB1_20920259_ChIP-Seq_GC1-SPG_Mouse1.16972739
87* ZFP281_18358816_ChIP-ChIP_MESCs_Mouse1.16950789
88* ZFX_18555785_ChIP-Seq_MESCs_Mouse1.16781610
89ASH2L_23239880_ChIP-Seq_MESCs_Mouse1.15671538
90GBX2_23144817_ChIP-Seq_PC3_Human1.14197752
91IRF1_19129219_ChIP-ChIP_H3396_Human1.13854660
92XRN2_22483619_ChIP-Seq_HELA_Human1.11746295
93SREBP1_19666523_ChIP-Seq_LIVER_Mouse1.10299394
94SALL4_18804426_ChIP-ChIP_XEN_Mouse1.09917829
95SOX17_20123909_ChIP-Seq_XEN_Mouse1.08843822
96FOXM1_23109430_ChIP-Seq_U2OS_Human1.08706266
97KLF4_19030024_ChIP-ChIP_MESCs_Mouse1.08564013
98RCOR1_19997604_ChIP-ChIP_NEURONS_Mouse1.07569212
99ZFP322A_24550733_ChIP-Seq_MESCs_Mouse1.06940045
100CEBPD_23245923_ChIP-Seq_MEFs_Mouse1.06108591
101PPARG_19300518_ChIP-PET_3T3-L1_Mouse1.06048843
102FOXP2_21765815_ChIP-ChIP_NEURO2A_Mouse1.05248680
103DMRT1_21621532_ChIP-ChIP_FETAL_Ovary1.03856777
104GATA4_21415370_ChIP-Seq_HL-1_Mouse1.02479649
105KDM5A_27292631_Chip-Seq_BREAST_Human1.02248560
106TCF3_18692474_ChIP-Seq_MEFs_Mouse1.02064103
107RNF2_27304074_Chip-Seq_NSC_Mouse1.01823997
108NANOG_18358816_ChIP-ChIP_MESCs_Mouse1.01453779
109SMARCA4_20176728_ChIP-ChIP_TSCs_Mouse1.00762454
110* TCFAP2C_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse1.00375003
111* CCND1_20090754_ChIP-ChIP_RETINA_Mouse0.98514259
112SOX2_16153702_ChIP-ChIP_HESCs_Human0.98447511
113ZFP57_27257070_Chip-Seq_ESCs_Mouse0.97004414
114MYC_18940864_ChIP-ChIP_HL60_Human0.96214421
115E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human0.95202988
116ASXL1_24218140_ChIP-Seq_BMDM_Mouse0.95194187
117ESR1_15608294_ChIP-ChIP_MCF-7_Human0.94717073
118TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse0.94098752
119* TCFCP2L1_18555785_ChIP-Seq_MESCs_Mouse0.93968347
120WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse0.93630768
121P300_19829295_ChIP-Seq_ESCs_Human0.93414195
122HNF4A_19761587_ChIP-ChIP_CACO-2_Human0.93318696
123BCL3_23251550_ChIP-Seq_MUSCLE_Mouse0.93281076
124ZIC3_20872845_ChIP-ChIP_MESCs_Mouse0.92199250
125SOX2_19030024_ChIP-ChIP_MESCs_Mouse0.91697266
126SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse0.88281541
127SMAD4_19686287_ChIP-ChIP_HaCaT_Human0.87916650
128IGF1R_20145208_ChIP-Seq_DFB_Human0.84001582
129ERG_20887958_ChIP-Seq_HPC-7_Mouse0.83622631
130JUN_21703547_ChIP-Seq_K562_Human0.82718844
131* TFEB_21752829_ChIP-Seq_HELA_Human0.81473102
132TAF15_26573619_Chip-Seq_HEK293_Human0.79317929
133POU5F1_18700969_ChIP-ChIP_MESCs_Mouse0.78090062
134BMI1_23680149_ChIP-Seq_NPCS_Mouse0.77114657

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0009697_abnormal_copulation3.26369304
2MP0003123_paternal_imprinting3.13322784
3MP0008007_abnormal_cellular_replicative2.79284810
4MP0005408_hypopigmentation2.71318852
5MP0003787_abnormal_imprinting2.65744487
6MP0010094_abnormal_chromosome_stability2.57036139
7MP0000372_irregular_coat_pigmentation2.55528592
8MP0003121_genomic_imprinting2.52747371
9MP0008058_abnormal_DNA_repair2.46707812
10MP0003693_abnormal_embryo_hatching2.33054530
11MP0001986_abnormal_taste_sensitivity2.31235037
12MP0002160_abnormal_reproductive_system2.23980077
13MP0008877_abnormal_DNA_methylation2.21351386
14MP0002876_abnormal_thyroid_physiology2.17641340
15MP0000566_synostosis2.12309167
16MP0001188_hyperpigmentation2.11037802
17MP0008057_abnormal_DNA_replication2.09750894
18MP0002009_preneoplasia2.08779982
19MP0004957_abnormal_blastocyst_morpholog2.05384997
20MP0008789_abnormal_olfactory_epithelium2.02903874
21MP0000537_abnormal_urethra_morphology2.01852424
22MP0003077_abnormal_cell_cycle2.00863265
23MP0005367_renal/urinary_system_phenotyp1.98734213
24MP0000516_abnormal_urinary_system1.98734213
25MP0006292_abnormal_olfactory_placode1.98181847
26MP0004782_abnormal_surfactant_physiolog1.97516085
27MP0003786_premature_aging1.96437133
28MP0008932_abnormal_embryonic_tissue1.95166820
29MP0003122_maternal_imprinting1.85251143
30MP0005171_absent_coat_pigmentation1.83067865
31MP0002751_abnormal_autonomic_nervous1.81033770
32MP0003111_abnormal_nucleus_morphology1.74868738
33MP0009053_abnormal_anal_canal1.69181379
34MP0009672_abnormal_birth_weight1.67992975
35MP0010234_abnormal_vibrissa_follicle1.67854923
36MP0003718_maternal_effect1.67171063
37MP0005394_taste/olfaction_phenotype1.66896034
38MP0005499_abnormal_olfactory_system1.66896034
39MP0001348_abnormal_lacrimal_gland1.64771664
40MP0002084_abnormal_developmental_patter1.64349046
41MP0005389_reproductive_system_phenotype1.62395667
42MP0005503_abnormal_tendon_morphology1.60913239
43MP0005075_abnormal_melanosome_morpholog1.60882013
44MP0004272_abnormal_basement_membrane1.59753025
45MP0003186_abnormal_redox_activity1.56950308
46MP0010352_gastrointestinal_tract_polyps1.56528948
47MP0001919_abnormal_reproductive_system1.52891092
48MP0001177_atelectasis1.52711636
49MP0003942_abnormal_urinary_system1.51822366
50MP0000015_abnormal_ear_pigmentation1.47434205
51MP0001299_abnormal_eye_distance/1.45730770
52MP0002697_abnormal_eye_size1.45214629
53MP0003806_abnormal_nucleotide_metabolis1.44462321
54MP0001293_anophthalmia1.41067882
55MP0003890_abnormal_embryonic-extraembry1.40327665
56MP0003315_abnormal_perineum_morphology1.37976643
57MP0002085_abnormal_embryonic_tissue1.34996223
58MP0000751_myopathy1.34877991
59MP0000749_muscle_degeneration1.29938460
60MP0002877_abnormal_melanocyte_morpholog1.28844950
61MP0010030_abnormal_orbit_morphology1.28842563
62MP0002269_muscular_atrophy1.27957907
63MP0009780_abnormal_chondrocyte_physiolo1.27655180
64MP0002080_prenatal_lethality1.26377622
65MP0003941_abnormal_skin_development1.24519245
66MP0003567_abnormal_fetal_cardiomyocyte1.24218055
67MP0001119_abnormal_female_reproductive1.23143908
68MP0001661_extended_life_span1.21074536
69MP0002163_abnormal_gland_morphology1.20253492
70MP0005187_abnormal_penis_morphology1.19468501
71MP0004233_abnormal_muscle_weight1.19424127
72MP0008438_abnormal_cutaneous_collagen1.19387571
73MP0005623_abnormal_meninges_morphology1.17158068
74MP0003943_abnormal_hepatobiliary_system1.16813189
75MP0009703_decreased_birth_body1.16625843
76MP0005646_abnormal_pituitary_gland1.15851352
77MP0006054_spinal_hemorrhage1.12772587
78MP0002653_abnormal_ependyma_morphology1.12183958
79MP0000049_abnormal_middle_ear1.11092592
80MP0004087_abnormal_muscle_fiber1.10663414
81MP0002092_abnormal_eye_morphology1.10370763
82MP0001542_abnormal_bone_strength1.10192451
83MP0000350_abnormal_cell_proliferation1.07918350
84MP0002086_abnormal_extraembryonic_tissu1.06847714
85MP0001984_abnormal_olfaction1.06309251
86MP0010630_abnormal_cardiac_muscle1.06274050
87MP0001764_abnormal_homeostasis1.06142514
88MP0001346_abnormal_lacrimal_gland1.05641553
89MP0001186_pigmentation_phenotype1.02404590
90MP0002938_white_spotting1.02211523
91MP0000681_abnormal_thyroid_gland1.02161182
92MP0000762_abnormal_tongue_morphology1.00774971
93MP0004197_abnormal_fetal_growth/weight/1.00466456
94MP0003115_abnormal_respiratory_system0.99841733
95MP0001672_abnormal_embryogenesis/_devel0.99642901
96MP0005380_embryogenesis_phenotype0.99642901
97MP0000747_muscle_weakness0.99118345
98MP0003705_abnormal_hypodermis_morpholog0.98010113
99MP0000462_abnormal_digestive_system0.94032142
100MP0009379_abnormal_foot_pigmentation0.93936499
101MP0003221_abnormal_cardiomyocyte_apopto0.92697096
102MP0003935_abnormal_craniofacial_develop0.92690165
103MP0000678_abnormal_parathyroid_gland0.92496864
104MP0000759_abnormal_skeletal_muscle0.91231247
105MP0005330_cardiomyopathy0.91096446
106MP0008995_early_reproductive_senescence0.90929233
107MP0002735_abnormal_chemical_nociception0.90376934
108MP0003385_abnormal_body_wall0.90321403
109MP0003755_abnormal_palate_morphology0.87495983
110MP0009250_abnormal_appendicular_skeleto0.87164774
111MP0002210_abnormal_sex_determination0.86673366
112MP0002108_abnormal_muscle_morphology0.86495200
113MP0003984_embryonic_growth_retardation0.86133931
114MP0000428_abnormal_craniofacial_morphol0.85917303
115MP0003950_abnormal_plasma_membrane0.84755203
116MP0003136_yellow_coat_color0.84622147
117MP0003861_abnormal_nervous_system0.82674488
118MP0002638_abnormal_pupillary_reflex0.82639205
119MP0002088_abnormal_embryonic_growth/wei0.82239879
120MP0002114_abnormal_axial_skeleton0.80724005
121MP0001915_intracranial_hemorrhage0.80626341
122MP0001849_ear_inflammation0.80466424
123MP0001730_embryonic_growth_arrest0.80164128
124MP0001697_abnormal_embryo_size0.80133276
125MP0004084_abnormal_cardiac_muscle0.80079431
126MP0001145_abnormal_male_reproductive0.79196509
127MP0002233_abnormal_nose_morphology0.79178546
128MP0005084_abnormal_gallbladder_morpholo0.79038374
129MP0003119_abnormal_digestive_system0.78727061
130MP0010368_abnormal_lymphatic_system0.78489728
131MP0002249_abnormal_larynx_morphology0.78337383
132MP0001286_abnormal_eye_development0.77858794
133MP0005395_other_phenotype0.76866062
134MP0010307_abnormal_tumor_latency0.76830524
135MP0004133_heterotaxia0.76679286
136MP0001929_abnormal_gametogenesis0.76407229
137MP0002177_abnormal_outer_ear0.74966780
138MP0002095_abnormal_skin_pigmentation0.74781442
139MP0002132_abnormal_respiratory_system0.74187899
140MP0005220_abnormal_exocrine_pancreas0.72530870
141MP0003937_abnormal_limbs/digits/tail_de0.71148392
142MP0000534_abnormal_ureter_morphology0.69148635
143MP0001529_abnormal_vocalization0.68821047
144MP0001879_abnormal_lymphatic_vessel0.68429277
145MP0002109_abnormal_limb_morphology0.68110308
146MP0000490_abnormal_crypts_of0.67360471
147MP0000432_abnormal_head_morphology0.66841950
148MP0002111_abnormal_tail_morphology0.66557070
149MP0002075_abnormal_coat/hair_pigmentati0.65639476

Predicted human phenotypes

RankGene SetZ-score
1Exercise-induced muscle cramps (HP:0003710)4.28191976
2Abnormality of the anterior horn cell (HP:0006802)4.04862415
3Degeneration of anterior horn cells (HP:0002398)4.04862415
4Birth length less than 3rd percentile (HP:0003561)3.88588486
5Spinal cord lesions (HP:0100561)3.88320687
6Syringomyelia (HP:0003396)3.88320687
7Hypothermia (HP:0002045)3.77452434
8Tongue fasciculations (HP:0001308)3.42013993
9Abnormal hair whorl (HP:0010721)3.34628725
10Abnormality of glycolysis (HP:0004366)3.23958662
11Asymmetry of the thorax (HP:0001555)3.15240095
12Selective tooth agenesis (HP:0001592)3.14635057
13Exercise-induced myalgia (HP:0003738)3.12288575
14Subaortic stenosis (HP:0001682)3.09708994
15Abnormality of the left ventricular outflow tract (HP:0011103)3.09708994
16Type I transferrin isoform profile (HP:0003642)2.97763165
17Nephroblastoma (Wilms tumor) (HP:0002667)2.94802280
18Increased serum pyruvate (HP:0003542)2.93311541
19Embryonal renal neoplasm (HP:0011794)2.85638056
20Muscle fibrillation (HP:0010546)2.82310837
21Abnormal lung lobation (HP:0002101)2.81040936
22True hermaphroditism (HP:0010459)2.75279854
23Impulsivity (HP:0100710)2.72335868
24Cortical dysplasia (HP:0002539)2.70766470
25Long foot (HP:0001833)2.70303752
26Abnormality of the labia minora (HP:0012880)2.70171404
27Cutaneous melanoma (HP:0012056)2.68615687
28Pancreatic fibrosis (HP:0100732)2.60479142
29Chromsome breakage (HP:0040012)2.57980111
30Chromosomal breakage induced by crosslinking agents (HP:0003221)2.52426660
31Neoplasm of the adrenal cortex (HP:0100641)2.46341079
32Neoplasm of the adrenal gland (HP:0100631)2.44915327
33Thyroid carcinoma (HP:0002890)2.44200969
34Osteomalacia (HP:0002749)2.44169593
35Alveolar cell carcinoma (HP:0006519)2.40448696
36Shoulder girdle muscle weakness (HP:0003547)2.39759116
37Hyperinsulinemic hypoglycemia (HP:0000825)2.39563071
38Increased nuchal translucency (HP:0010880)2.37797826
3911 pairs of ribs (HP:0000878)2.32754372
40Intestinal atresia (HP:0011100)2.30929005
41Calcaneovalgus deformity (HP:0001848)2.30771064
42Supernumerary spleens (HP:0009799)2.30521502
43Abnormal cartilage morphology (HP:0002763)2.29481101
44Medial flaring of the eyebrow (HP:0010747)2.26886129
45Rimmed vacuoles (HP:0003805)2.26867870
46Poor coordination (HP:0002370)2.26250863
47Congenital primary aphakia (HP:0007707)2.25254876
48Nephrogenic diabetes insipidus (HP:0009806)2.23394424
49Multiple enchondromatosis (HP:0005701)2.22402806
50Aplastic anemia (HP:0001915)2.21634320
51Patellar aplasia (HP:0006443)2.18108977
52Papillary thyroid carcinoma (HP:0002895)2.15831299
53Hypoglycemic seizures (HP:0002173)2.15778193
54Abnormality of incisor morphology (HP:0011063)2.15680885
55Aplasia/Hypoplasia of the tibia (HP:0005772)2.14758082
56Rectovaginal fistula (HP:0000143)2.11020523
57Rectal fistula (HP:0100590)2.11020523
58Hypoglycemic coma (HP:0001325)2.10888103
59Gait imbalance (HP:0002141)2.09348071
60Meningioma (HP:0002858)2.08979708
61Breast hypoplasia (HP:0003187)2.08321655
62Calf muscle hypertrophy (HP:0008981)2.07896819
63Aplasia/Hypoplasia of the patella (HP:0006498)2.07108119
64Short tibia (HP:0005736)2.04355269
65Shawl scrotum (HP:0000049)2.04092232
66Postaxial foot polydactyly (HP:0001830)2.02558716
67Intestinal fistula (HP:0100819)2.02190010
68Abnormality of the nasal septum (HP:0000419)2.01573646
69Increased CSF lactate (HP:0002490)2.01401638
70Proximal tubulopathy (HP:0000114)1.99865994
71Microvesicular hepatic steatosis (HP:0001414)1.99443328
72Gout (HP:0001997)1.98862824
73Deep philtrum (HP:0002002)1.98756996
74Myoglobinuria (HP:0002913)1.98732586
75Vertebral compression fractures (HP:0002953)1.98653969
76Renal cortical cysts (HP:0000803)1.98074177
77Decreased number of large peripheral myelinated nerve fibers (HP:0003387)1.95705406
78Optic nerve coloboma (HP:0000588)1.95304559
79Gonadotropin excess (HP:0000837)1.95035911
80Atrophy/Degeneration involving motor neurons (HP:0007373)1.94881976
81Preaxial hand polydactyly (HP:0001177)1.94648871
82Type 2 muscle fiber atrophy (HP:0003554)1.93281386
83Hepatoblastoma (HP:0002884)1.93091005
84Abnormality of the calcaneus (HP:0008364)1.92801075
85Tubulointerstitial nephritis (HP:0001970)1.92137859
86Nemaline bodies (HP:0003798)1.90010688
87Turricephaly (HP:0000262)1.89610898
88Abnormality of the metopic suture (HP:0005556)1.89297298
89Deformed tarsal bones (HP:0008119)1.89146867
90Neoplasm of the tracheobronchial system (HP:0100552)1.88758871
91High anterior hairline (HP:0009890)1.88297585
92Muscle hypertrophy of the lower extremities (HP:0008968)1.87309943
93Pancreatic cysts (HP:0001737)1.86382237
94Prominent metopic ridge (HP:0005487)1.84650151
95Back pain (HP:0003418)1.84007731
96Carpal bone hypoplasia (HP:0001498)1.83202669
97Ectopic kidney (HP:0000086)1.82288739
98Metaphyseal dysplasia (HP:0100255)1.82142596
99Meckel diverticulum (HP:0002245)1.81720787
100Rhabdomyolysis (HP:0003201)1.80946959
101Enlarged kidneys (HP:0000105)1.80247278
102Adrenal hypoplasia (HP:0000835)1.80167259
103Long clavicles (HP:0000890)1.79194325
104Abnormality of the phalanges of the hallux (HP:0010057)1.79177556
105Aplasia/Hypoplasia of the optic nerve (HP:0008058)1.78980262
106Progressive macrocephaly (HP:0004481)1.77910970
107Reticulocytopenia (HP:0001896)1.77826970
108Acute necrotizing encephalopathy (HP:0006965)1.77347278
109Muscle fiber cytoplasmatic inclusion bodies (HP:0100303)1.77162356
110Broad foot (HP:0001769)1.76858246
111Pancreatic islet-cell hyperplasia (HP:0004510)1.76562669
112Muscle fiber inclusion bodies (HP:0100299)1.75614298
113Facial cleft (HP:0002006)1.74579124
114Absent eyebrow (HP:0002223)1.74366536
115Abnormal ventriculo-arterial connection (HP:0011563)1.74170976
116Transposition of the great arteries (HP:0001669)1.74170976
117Abnormal connection of the cardiac segments (HP:0011545)1.74170976
118Missing ribs (HP:0000921)1.73891692
119Abnormality of the ileum (HP:0001549)1.73537831
120Abnormality of the pancreatic islet cells (HP:0006476)1.71765833
121Abnormality of endocrine pancreas physiology (HP:0012093)1.71765833
122Abnormal mitochondria in muscle tissue (HP:0008316)1.71455961
123Centrally nucleated skeletal muscle fibers (HP:0003687)1.70864905
124Macrocytic anemia (HP:0001972)1.69846212
125Cystic hygroma (HP:0000476)1.69698951
126Abnormal isoelectric focusing of serum transferrin (HP:0003160)1.68681808
127Abnormal protein N-linked glycosylation (HP:0012347)1.68681808
128Abnormal protein glycosylation (HP:0012346)1.68681808
129Abnormal glycosylation (HP:0012345)1.68681808
130Overlapping toe (HP:0001845)1.68611013
131Fibular hypoplasia (HP:0003038)1.65942774
132Proximal placement of thumb (HP:0009623)1.65399156
133Vaginal fistula (HP:0004320)1.64954074
134Abnormality of the intrinsic pathway (HP:0010989)1.64587848
135Neuroblastoma (HP:0003006)1.64015881
136Primitive neuroectodermal tumor (HP:0030065)1.64015881
137Neuroblastic tumors (HP:0004376)1.64015881
138Peripheral primitive neuroectodermal neoplasm (HP:0030067)1.64015881
139Sleep apnea (HP:0010535)1.63883198
140Termporal pattern (HP:0011008)1.63775826
141Insidious onset (HP:0003587)1.63775826
142Aplasia/Hypoplasia of the sternum (HP:0006714)1.63555163
143Hypoplastic left heart (HP:0004383)1.62901075
144Sloping forehead (HP:0000340)1.62480728
145Choanal stenosis (HP:0000452)1.62439405
146Unilateral renal agenesis (HP:0000122)1.62215329
147Deviation of the thumb (HP:0009603)1.61941016
148Occipital encephalocele (HP:0002085)1.61899851
149Spastic diplegia (HP:0001264)1.61835053
150Breech presentation (HP:0001623)1.61469512
151Capillary hemangiomas (HP:0005306)1.61086456
152Agnosia (HP:0010524)1.60939300
153Abnormal gallbladder physiology (HP:0012438)1.56995753
154Cholecystitis (HP:0001082)1.56995753
155Abnormality of the calf musculature (HP:0001430)1.56293721
156Pterygium (HP:0001059)1.51677516
157Vertebral arch anomaly (HP:0008438)1.51283687
158Abnormality of the hip-girdle musculature (HP:0001445)1.50342308
159Abnormality of the musculature of the pelvis (HP:0001469)1.50342308
160Abnormality of the fetal cardiovascular system (HP:0010948)1.50196220
161Abnormal umbilical cord blood vessels (HP:0011403)1.50196220
162Single umbilical artery (HP:0001195)1.50196220
163Abnormality of the umbilical cord (HP:0010881)1.50184325
164Neoplasm of the peripheral nervous system (HP:0100007)1.49726344
165Distal arthrogryposis (HP:0005684)1.49555700
166Limb-girdle muscle atrophy (HP:0003797)1.49439498
167Hammertoe (HP:0001765)1.49427448
168Pelvic girdle muscle weakness (HP:0003749)1.49296796
169Volvulus (HP:0002580)1.49021004
170Microglossia (HP:0000171)1.48826983
171Embryonal neoplasm (HP:0002898)1.46557624
172Pseudobulbar signs (HP:0002200)1.44068560
173Popliteal pterygium (HP:0009756)1.42895135
174Bifid scrotum (HP:0000048)1.42715279
175Limb-girdle muscle weakness (HP:0003325)1.42693805
176Alacrima (HP:0000522)1.42350386
177Broad palm (HP:0001169)1.40781969
178Insomnia (HP:0100785)1.39345970
179Abnormality of methionine metabolism (HP:0010901)1.39083345
180Rhizomelia (HP:0008905)1.38384351
181Hyperglycinemia (HP:0002154)1.38326944
182Pheochromocytoma (HP:0002666)1.38226092
183Muscle stiffness (HP:0003552)1.38187172
184Metatarsus adductus (HP:0001840)1.37938587
185Medulloblastoma (HP:0002885)1.37355256
186Abnormality of the salivary glands (HP:0010286)1.37311095
187Large hands (HP:0001176)1.37168553

Predicted kinase interactions (KEA)

RankGene SetZ-score
1CASK3.79595206
2AKT33.27556196
3ZAK3.22444690
4MKNK13.20708153
5MKNK23.05982545
6ERBB32.93455503
7TSSK62.67663414
8SIK32.58364999
9EEF2K2.49362961
10SGK22.28174693
11BRSK22.28012827
12SRPK12.26809027
13EIF2AK12.26685828
14STK38L2.18290684
15FRK2.17940622
16PLK32.17105144
17PLK21.95064150
18LATS21.91735556
19YES11.91266295
20PRPF4B1.90009923
21BMPR21.82913316
22CDC71.80764242
23PNCK1.79980753
24WEE11.79733523
25LATS11.78406966
26CCNB11.72351294
27MAP3K141.66616628
28MAPKAPK51.65952384
29PLK41.59942610
30CDK81.57066841
31NEK11.52630322
32EIF2AK31.44051818
33BCR1.42701246
34TAF11.41506615
35PASK1.38988466
36MAP3K101.38516571
37CDK121.37656338
38SGK4941.33676083
39SGK2231.33676083
40PDGFRA1.28154245
41SGK31.27194920
42BUB11.26519346
43NEK91.25713697
44NEK61.20595495
45MAP2K71.18644389
46VRK21.18420917
47RPS6KB21.17035933
48SMG11.15806723
49VRK11.14383405
50NEK21.13332010
51CDK61.11306279
52BRSK11.09578860
53STK241.06968860
54PRKD31.04406519
55TAOK21.04087896
56EIF2AK21.02840380
57PLK11.02833957
58CDK191.01149828
59FGFR21.01026675
60PDK40.98793568
61PDK30.98793568
62RIPK10.96300317
63MAP3K120.95611010
64LIMK10.94691547
65RPS6KA40.94585629
66ACVR1B0.87961850
67TESK10.86513336
68TRIM280.85297293
69NTRK10.85260754
70ICK0.84607667
71RPS6KB10.84587702
72STK160.82819764
73STK390.81849289
74MYLK0.81537616
75MST40.78990549
76PDK20.78878972
77MET0.78821663
78BMPR1B0.78781834
79BRAF0.78747778
80AKT20.77490901
81ATR0.77364610
82PAK20.76710963
83TRPM70.76686920
84NME20.76522908
85DMPK0.73521114
86FGFR10.73418497
87CSNK1E0.72542461
88PKN20.71200440
89CHEK20.69784246
90CHUK0.69173525
91RPS6KL10.66951893
92RPS6KC10.66951893
93ERBB40.66341932
94MAPK130.66259877
95ALK0.64608073
96AURKA0.63254677
97CDK90.63037635
98PIM10.62529232
99KSR20.61471587
100TTK0.61083756
101CSNK1G10.59133044
102CDK11A0.59037582
103RPS6KA60.58782605
104CDK140.57932292
105CSNK2A10.57034603
106TNIK0.54856369
107CDK70.54694973
108PHKG10.54336136
109PHKG20.54336136
110CSNK1A1L0.52976752
111CSNK1G30.52877385
112CDK180.52499101
113PBK0.52360737
114EPHA20.51460913
115CDK150.50904862
116ATM0.50844792
117FGFR40.50041844
118ADRBK20.48475935
119KSR10.48404510
120NUAK10.48301342
121NLK0.48124174
122MTOR0.48121146
123STK40.48029633
124STK30.47943022
125BRD40.47370204
126PRKDC0.46784722
127CDK40.45352385
128PIK3CA0.44480260
129AURKB0.44335471
130TGFBR10.43560637
131NME10.42639277
132TXK0.38684538
133CHEK10.38265840
134TNK20.37240572
135WNK30.37082176
136FGFR30.36851346
137SCYL20.36476831
138CDK20.35543719
139OBSCN0.33518617
140CDK30.32603394
141IRAK40.32451853
142CSNK2A20.32425639
143CLK10.31997790
144DAPK10.31839764
145MINK10.30713427
146CDK10.30677465
147TEC0.26811074
148RPS6KA20.26159751
149PRKCG0.24949228
150AKT10.23738994

Predicted pathways (KEGG)

RankGene SetZ-score
1Proteasome_Homo sapiens_hsa030503.82639184
2Mismatch repair_Homo sapiens_hsa034303.69736270
3DNA replication_Homo sapiens_hsa030303.59892498
4Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030083.38760112
5Base excision repair_Homo sapiens_hsa034102.94707754
6One carbon pool by folate_Homo sapiens_hsa006702.84604133
7RNA polymerase_Homo sapiens_hsa030202.71366877
8Cell cycle_Homo sapiens_hsa041102.59346178
9Basal transcription factors_Homo sapiens_hsa030222.58667520
10Spliceosome_Homo sapiens_hsa030402.56368124
11Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009702.53497127
12RNA transport_Homo sapiens_hsa030132.51515528
13Nucleotide excision repair_Homo sapiens_hsa034202.50490291
14Homologous recombination_Homo sapiens_hsa034402.42822208
15RNA degradation_Homo sapiens_hsa030182.34122358
16Protein export_Homo sapiens_hsa030602.17007677
17Pyrimidine metabolism_Homo sapiens_hsa002401.99876947
18Propanoate metabolism_Homo sapiens_hsa006401.96197771
19Fanconi anemia pathway_Homo sapiens_hsa034601.94567026
20Citrate cycle (TCA cycle)_Homo sapiens_hsa000201.86273766
21Ribosome_Homo sapiens_hsa030101.77046967
22Non-homologous end-joining_Homo sapiens_hsa034501.76786523
23Glycine, serine and threonine metabolism_Homo sapiens_hsa002601.70731193
24Valine, leucine and isoleucine degradation_Homo sapiens_hsa002801.66486891
25Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004001.64496595
26Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006031.61856738
27Taurine and hypotaurine metabolism_Homo sapiens_hsa004301.60994967
28mRNA surveillance pathway_Homo sapiens_hsa030151.60105152
29Purine metabolism_Homo sapiens_hsa002301.42271463
30Pentose phosphate pathway_Homo sapiens_hsa000301.41209721
31Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005331.36391692
32Fatty acid degradation_Homo sapiens_hsa000711.28117666
33Fatty acid metabolism_Homo sapiens_hsa012121.27805516
34Arginine and proline metabolism_Homo sapiens_hsa003301.22458023
35Adherens junction_Homo sapiens_hsa045201.20890140
36Pantothenate and CoA biosynthesis_Homo sapiens_hsa007701.19668624
37Huntingtons disease_Homo sapiens_hsa050161.17635383
38Arachidonic acid metabolism_Homo sapiens_hsa005901.15126176
39Epstein-Barr virus infection_Homo sapiens_hsa051691.13028619
40beta-Alanine metabolism_Homo sapiens_hsa004101.09033161
41SNARE interactions in vesicular transport_Homo sapiens_hsa041301.08887521
42Vitamin B6 metabolism_Homo sapiens_hsa007501.08025107
43Arginine biosynthesis_Homo sapiens_hsa002201.07202674
44Pathogenic Escherichia coli infection_Homo sapiens_hsa051301.01958655
45Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049641.01161160
46Collecting duct acid secretion_Homo sapiens_hsa049661.00159040
47Thyroid cancer_Homo sapiens_hsa052160.99405155
48Lysine degradation_Homo sapiens_hsa003100.97804945
49p53 signaling pathway_Homo sapiens_hsa041150.97342576
50Vibrio cholerae infection_Homo sapiens_hsa051100.96848227
51Circadian rhythm_Homo sapiens_hsa047100.95179844
52Folate biosynthesis_Homo sapiens_hsa007900.94339440
53Melanoma_Homo sapiens_hsa052180.94179232
54Central carbon metabolism in cancer_Homo sapiens_hsa052300.93445888
55Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.91625610
56Steroid biosynthesis_Homo sapiens_hsa001000.91057022
57Legionellosis_Homo sapiens_hsa051340.88988303
58Oxidative phosphorylation_Homo sapiens_hsa001900.88731560
59Pentose and glucuronate interconversions_Homo sapiens_hsa000400.87131323
60Parkinsons disease_Homo sapiens_hsa050120.84352118
61Selenocompound metabolism_Homo sapiens_hsa004500.84143557
62Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.82606770
63Cyanoamino acid metabolism_Homo sapiens_hsa004600.77247564
64Phagosome_Homo sapiens_hsa041450.76200633
65Butirosin and neomycin biosynthesis_Homo sapiens_hsa005240.75974443
66AMPK signaling pathway_Homo sapiens_hsa041520.73601689
67Wnt signaling pathway_Homo sapiens_hsa043100.72696095
68Prostate cancer_Homo sapiens_hsa052150.72570462
69Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.70880201
70N-Glycan biosynthesis_Homo sapiens_hsa005100.70861466
71Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001300.70579405
72Synaptic vesicle cycle_Homo sapiens_hsa047210.69716193
73Tight junction_Homo sapiens_hsa045300.69260713
74Drug metabolism - other enzymes_Homo sapiens_hsa009830.68815962
75Basal cell carcinoma_Homo sapiens_hsa052170.68689547
76Type I diabetes mellitus_Homo sapiens_hsa049400.68439175
77TGF-beta signaling pathway_Homo sapiens_hsa043500.68392367
782-Oxocarboxylic acid metabolism_Homo sapiens_hsa012100.67994369
79Glucagon signaling pathway_Homo sapiens_hsa049220.67773667
80Galactose metabolism_Homo sapiens_hsa000520.66902983
81Ascorbate and aldarate metabolism_Homo sapiens_hsa000530.66035585
82Butanoate metabolism_Homo sapiens_hsa006500.66035418
83Synthesis and degradation of ketone bodies_Homo sapiens_hsa000720.65880328
84Phototransduction_Homo sapiens_hsa047440.65446496
85Pyruvate metabolism_Homo sapiens_hsa006200.64413498
86Hedgehog signaling pathway_Homo sapiens_hsa043400.63121798
87Cysteine and methionine metabolism_Homo sapiens_hsa002700.62745203
88Oocyte meiosis_Homo sapiens_hsa041140.61030649
89Herpes simplex infection_Homo sapiens_hsa051680.60909296
90Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010400.60686380
91Carbon metabolism_Homo sapiens_hsa012000.58431064
92Insulin signaling pathway_Homo sapiens_hsa049100.58365045
93Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.56939865
94Cytosolic DNA-sensing pathway_Homo sapiens_hsa046230.56805413
95Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.56740515
96Vasopressin-regulated water reabsorption_Homo sapiens_hsa049620.56722070
97Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.54266679
98Viral carcinogenesis_Homo sapiens_hsa052030.53969542
99Histidine metabolism_Homo sapiens_hsa003400.52446553
100Hippo signaling pathway_Homo sapiens_hsa043900.51457183
101Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005320.50968921
102Biosynthesis of amino acids_Homo sapiens_hsa012300.50244501
103Bacterial invasion of epithelial cells_Homo sapiens_hsa051000.50153669
104Autoimmune thyroid disease_Homo sapiens_hsa053200.50134628
105Antigen processing and presentation_Homo sapiens_hsa046120.49723137
106Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.48777329
107Fatty acid elongation_Homo sapiens_hsa000620.47811004
108Thyroid hormone signaling pathway_Homo sapiens_hsa049190.47021289
109Fructose and mannose metabolism_Homo sapiens_hsa000510.45262261
110Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006300.44743509
111Glutathione metabolism_Homo sapiens_hsa004800.44710364
112Sulfur relay system_Homo sapiens_hsa041220.43900266
113Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.42580023
114mTOR signaling pathway_Homo sapiens_hsa041500.42240584
115Maturity onset diabetes of the young_Homo sapiens_hsa049500.41886728
116Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054120.41721207
117Starch and sucrose metabolism_Homo sapiens_hsa005000.41348072
118Phenylalanine metabolism_Homo sapiens_hsa003600.40807789
119Metabolic pathways_Homo sapiens_hsa011000.40295076
120Chronic myeloid leukemia_Homo sapiens_hsa052200.39664989
121Rheumatoid arthritis_Homo sapiens_hsa053230.38884084
122Endometrial cancer_Homo sapiens_hsa052130.37443993
123Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.36396472
124Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049610.35995197
125Longevity regulating pathway - mammal_Homo sapiens_hsa042110.35327272
126Allograft rejection_Homo sapiens_hsa053300.33575792
127MicroRNAs in cancer_Homo sapiens_hsa052060.33192126
128PI3K-Akt signaling pathway_Homo sapiens_hsa041510.33088614
129HTLV-I infection_Homo sapiens_hsa051660.31293390
130Peroxisome_Homo sapiens_hsa041460.29979790
131Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.29945624
132Measles_Homo sapiens_hsa051620.29742179
133Systemic lupus erythematosus_Homo sapiens_hsa053220.28179869
134Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.26850730
135Hepatitis B_Homo sapiens_hsa051610.22941407
136Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.22664747
137Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.21870517
138Alzheimers disease_Homo sapiens_hsa050100.21798584
139Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.20889610
140Tyrosine metabolism_Homo sapiens_hsa003500.19702615
141Colorectal cancer_Homo sapiens_hsa052100.19568138
142HIF-1 signaling pathway_Homo sapiens_hsa040660.18150544
143Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.17741880

Most similar genes based on co-expression Upload to Enrichr

Tissue Expression Export image »

Cell Line Expression Export image »