SRP14

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1mitochondrial ATP synthesis coupled proton transport (GO:0042776)7.18695376
2ATP synthesis coupled proton transport (GO:0015986)6.90243070
3energy coupled proton transport, down electrochemical gradient (GO:0015985)6.90243070
4mitochondrial electron transport, NADH to ubiquinone (GO:0006120)6.63265850
5central nervous system myelination (GO:0022010)6.57117407
6axon ensheathment in central nervous system (GO:0032291)6.57117407
7protein neddylation (GO:0045116)5.86767744
8respiratory electron transport chain (GO:0022904)5.66389877
9electron transport chain (GO:0022900)5.55043672
10chaperone-mediated protein transport (GO:0072321)5.41232215
11sequestering of actin monomers (GO:0042989)4.74304955
12fatty acid elongation (GO:0030497)4.68231904
13long-chain fatty acid biosynthetic process (GO:0042759)4.61007832
14establishment of protein localization to mitochondrial membrane (GO:0090151)4.40957028
15mitochondrial respiratory chain complex I assembly (GO:0032981)4.08200021
16NADH dehydrogenase complex assembly (GO:0010257)4.08200021
17mitochondrial respiratory chain complex I biogenesis (GO:0097031)4.08200021
18protein complex biogenesis (GO:0070271)4.07491962
19ribosomal small subunit biogenesis (GO:0042274)3.88905742
20substantia nigra development (GO:0021762)3.83278337
21hydrogen ion transmembrane transport (GO:1902600)3.82253656
22GTP biosynthetic process (GO:0006183)3.82026791
23platelet dense granule organization (GO:0060155)3.76515552
24mitochondrial respiratory chain complex assembly (GO:0033108)3.58889979
25myelination (GO:0042552)3.53888265
26epithelial cilium movement (GO:0003351)3.51344866
27nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291)3.50141776
28cytochrome complex assembly (GO:0017004)3.50107475
29axon ensheathment (GO:0008366)3.50101785
30ensheathment of neurons (GO:0007272)3.50101785
31proton transport (GO:0015992)3.48824808
32purine ribonucleoside triphosphate biosynthetic process (GO:0009206)3.47636247
33behavioral response to nicotine (GO:0035095)3.46682072
34dopamine biosynthetic process (GO:0042416)3.41908339
35hydrogen transport (GO:0006818)3.40068462
36purine nucleoside triphosphate biosynthetic process (GO:0009145)3.38684513
37ATP biosynthetic process (GO:0006754)3.37810377
38exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay 3.36051695
39response to redox state (GO:0051775)3.33896004
40ribosomal small subunit assembly (GO:0000028)3.31315180
41neuron cell-cell adhesion (GO:0007158)3.28888105
42proteasome assembly (GO:0043248)3.28757431
43DNA damage response, detection of DNA damage (GO:0042769)3.26010002
44negative regulation of neurotransmitter transport (GO:0051589)3.25283604
45intraciliary transport (GO:0042073)3.25002880
46RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394)3.22694217
47tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388)3.22694217
48GPI anchor biosynthetic process (GO:0006506)3.22147277
49* cotranslational protein targeting to membrane (GO:0006613)3.21876588
50viral transcription (GO:0019083)3.20465212
51cholesterol biosynthetic process (GO:0006695)3.19790776
52positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051437)3.18681247
53presynaptic membrane organization (GO:0097090)3.13726415
54energy coupled proton transmembrane transport, against electrochemical gradient (GO:0015988)3.13230041
55ATP hydrolysis coupled proton transport (GO:0015991)3.13230041
56DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest (GO:003.11156998
57regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051439)3.10463979
58mannosylation (GO:0097502)3.10334097
59regulation of dopamine metabolic process (GO:0042053)3.10205735
60regulation of catecholamine metabolic process (GO:0042069)3.10205735
61* protein targeting to ER (GO:0045047)3.10001198
62presynaptic membrane assembly (GO:0097105)3.09487069
63organelle disassembly (GO:1903008)3.08722576
64translational termination (GO:0006415)3.07901298
65regulation of mitochondrial translation (GO:0070129)3.05841669
66DNA deamination (GO:0045006)3.04587113
67inner mitochondrial membrane organization (GO:0007007)3.03512670
68* SRP-dependent cotranslational protein targeting to membrane (GO:0006614)3.03511249
69* protein localization to endoplasmic reticulum (GO:0070972)3.03251023
70protein-cofactor linkage (GO:0018065)3.02910284
71regulation of collateral sprouting (GO:0048670)3.02201543
72signal transduction involved in mitotic DNA damage checkpoint (GO:1902402)3.02188125
73signal transduction involved in mitotic cell cycle checkpoint (GO:0072413)3.02188125
74signal transduction involved in mitotic DNA integrity checkpoint (GO:1902403)3.02188125
75UTP biosynthetic process (GO:0006228)3.02036853
76pyrimidine nucleobase catabolic process (GO:0006208)2.99742124
77* establishment of protein localization to endoplasmic reticulum (GO:0072599)2.99319420
78signal transduction involved in mitotic G1 DNA damage checkpoint (GO:0072431)2.99046290
79intracellular signal transduction involved in G1 DNA damage checkpoint (GO:1902400)2.99046290
80ribonucleoside triphosphate biosynthetic process (GO:0009201)2.97508265
81epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287)2.97441074
82termination of RNA polymerase III transcription (GO:0006386)2.97421062
83transcription elongation from RNA polymerase III promoter (GO:0006385)2.97421062
84protein targeting to mitochondrion (GO:0006626)2.94831515
85oxidative phosphorylation (GO:0006119)2.94231168
86water-soluble vitamin biosynthetic process (GO:0042364)2.93677399
87sterol biosynthetic process (GO:0016126)2.89804461
88chromatin remodeling at centromere (GO:0031055)2.89033320
897-methylguanosine mRNA capping (GO:0006370)2.88789239
90establishment of protein localization to mitochondrion (GO:0072655)2.88651264
91RNA capping (GO:0036260)2.88421940
927-methylguanosine RNA capping (GO:0009452)2.88421940
93preassembly of GPI anchor in ER membrane (GO:0016254)2.88416204
94signal transduction involved in cell cycle checkpoint (GO:0072395)2.88263280
95GPI anchor metabolic process (GO:0006505)2.87529984
96dopamine transport (GO:0015872)2.86107943
97anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process (GO:02.85688802
98isoprenoid biosynthetic process (GO:0008299)2.83987714
99signal transduction involved in DNA integrity checkpoint (GO:0072401)2.83353071
100signal transduction involved in DNA damage checkpoint (GO:0072422)2.83353071
101respiratory chain complex IV assembly (GO:0008535)2.82565094
102DNA double-strand break processing (GO:0000729)2.82502472
103regulation of cellular amino acid metabolic process (GO:0006521)2.79646135
104CENP-A containing nucleosome assembly (GO:0034080)2.77878737
105cilium movement (GO:0003341)2.77462957
106L-methionine biosynthetic process from methylthioadenosine (GO:0019509)2.77411617
107nonmotile primary cilium assembly (GO:0035058)2.76604476
108negative regulation of ryanodine-sensitive calcium-release channel activity (GO:0060315)2.76375998
109translational elongation (GO:0006414)2.73211394
110negative regulation of protein localization to cell surface (GO:2000009)2.72765232
111calcium-mediated signaling using intracellular calcium source (GO:0035584)2.72182426
112mitochondrial fragmentation involved in apoptotic process (GO:0043653)2.72086833
113positive regulation of ubiquitin-protein transferase activity (GO:0051443)2.71909041
114regulation of cilium movement (GO:0003352)2.70608643
115neural nucleus development (GO:0048857)2.69864095
116cullin deneddylation (GO:0010388)2.69841438
117neuron fate determination (GO:0048664)2.69767120
118* translation (GO:0006412)2.69197416
119glycerophospholipid catabolic process (GO:0046475)2.68608866
120anterograde synaptic vesicle transport (GO:0048490)2.67307239
121protein localization to mitochondrion (GO:0070585)2.66894296
122spliceosomal snRNP assembly (GO:0000387)2.66550508
123aldehyde catabolic process (GO:0046185)2.65800163
124guanosine-containing compound biosynthetic process (GO:1901070)2.65724992
125establishment of viral latency (GO:0019043)2.59529328
126negative regulation of neurotransmitter secretion (GO:0046929)2.58597338
127pyrimidine deoxyribonucleotide catabolic process (GO:0009223)2.58544349
128negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436)2.58223669
129signal peptide processing (GO:0006465)2.57813668
130positive regulation of ligase activity (GO:0051351)2.56982288
131mitochondrial transport (GO:0006839)2.55620208
132cellular protein complex disassembly (GO:0043624)2.55266317
133viral life cycle (GO:0019058)2.55154328
134nucleoside diphosphate phosphorylation (GO:0006165)2.54854189
135nucleoside triphosphate biosynthetic process (GO:0009142)2.54658543
136negative regulation of execution phase of apoptosis (GO:1900118)2.53735795
137CTP metabolic process (GO:0046036)2.53565185
138CTP biosynthetic process (GO:0006241)2.53565185
139spliceosomal complex assembly (GO:0000245)2.53552879
140intracellular protein transmembrane import (GO:0044743)2.52681763
141antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent (GO:2.52581839
142negative regulation of ligase activity (GO:0051352)2.51994899
143negative regulation of ubiquitin-protein transferase activity (GO:0051444)2.51994899
144ribosomal large subunit biogenesis (GO:0042273)2.51788311
145regulation of feeding behavior (GO:0060259)2.50976423
146protein deneddylation (GO:0000338)2.50735157
147oligodendrocyte differentiation (GO:0048709)2.49874200
148peptidyl-histidine modification (GO:0018202)2.49617442
149ribonucleoprotein complex disassembly (GO:0032988)2.49427456
150neurotransmitter uptake (GO:0001504)2.48987141
151negative regulation of transcription regulatory region DNA binding (GO:2000678)2.48941506
152protein localization to cilium (GO:0061512)2.48255722

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1SOX9_22984422_ChIP-ChIP_TESTIS_Rat5.10925337
2E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse3.57108645
3CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human3.23086480
4KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human3.06168001
5* GABP_17652178_ChIP-ChIP_JURKAT_Human3.03242929
6EZH2_22144423_ChIP-Seq_EOC_Human2.83590760
7TAF15_26573619_Chip-Seq_HEK293_Human2.60762022
8EST1_17652178_ChIP-ChIP_JURKAT_Human2.59321406
9NOTCH1_17114293_ChIP-ChIP_T-ALL_Human2.58383967
10GBX2_23144817_ChIP-Seq_PC3_Human2.40358330
11TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse2.34613738
12* HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human2.31913010
13VDR_22108803_ChIP-Seq_LS180_Human2.30717701
14CHD1_19587682_ChIP-ChIP_MESCs_Mouse2.27762758
15MYCN_21190229_ChIP-Seq_SHEP-21N_Human2.21662591
16* JARID1A_20064375_ChIP-Seq_MESCs_Mouse2.16852656
17BMI1_23680149_ChIP-Seq_NPCS_Mouse2.14624271
18ZFP57_27257070_Chip-Seq_ESCs_Mouse2.09710029
19PDX1_19855005_ChIP-ChIP_MIN6_Mouse2.06750371
20CREB1_15753290_ChIP-ChIP_HEK293T_Human1.97063375
21ETS1_20019798_ChIP-Seq_JURKAT_Human1.91303821
22MYC_18940864_ChIP-ChIP_HL60_Human1.82321696
23JARID2_20064375_ChIP-Seq_MESCs_Mouse1.82248595
24EZH2_27304074_Chip-Seq_ESCs_Mouse1.80464461
25SUZ12_18692474_ChIP-Seq_MESCs_Mouse1.78722613
26HCFC1_20581084_ChIP-Seq_MESCs_Mouse1.75449022
27SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.75078609
28FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse1.69810626
29CBX2_27304074_Chip-Seq_ESCs_Mouse1.65262460
30CTBP1_25329375_ChIP-Seq_LNCAP_Human1.64249424
31ER_23166858_ChIP-Seq_MCF-7_Human1.64156060
32FUS_26573619_Chip-Seq_HEK293_Human1.63738997
33GLI1_17442700_ChIP-ChIP_MESCs_Mouse1.62487872
34POU3F2_20337985_ChIP-ChIP_501MEL_Human1.61241219
35SUZ12_18555785_ChIP-Seq_MESCs_Mouse1.60850895
36FOXP3_21729870_ChIP-Seq_TREG_Human1.60360050
37CTBP2_25329375_ChIP-Seq_LNCAP_Human1.59522520
38MYC_18555785_ChIP-Seq_MESCs_Mouse1.58490245
39NR4A2_19515692_ChIP-ChIP_MN9D_Mouse1.56716291
40EED_16625203_ChIP-ChIP_MESCs_Mouse1.56589913
41SUZ12_18692474_ChIP-Seq_MEFs_Mouse1.48971528
42GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.48355851
43OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.45986386
44SUZ12_18974828_ChIP-Seq_MESCs_Mouse1.45461953
45SUZ12_16625203_ChIP-ChIP_MESCs_Mouse1.44620904
46PHC1_16625203_ChIP-ChIP_MESCs_Mouse1.44556633
47* SRF_21415370_ChIP-Seq_HL-1_Mouse1.41308464
48E2F4_17652178_ChIP-ChIP_JURKAT_Human1.38840593
49P300_19829295_ChIP-Seq_ESCs_Human1.38769748
50JARID2_20075857_ChIP-Seq_MESCs_Mouse1.38739580
51PADI4_21655091_ChIP-ChIP_MCF-7_Human1.36281535
52CEBPB_24764292_ChIP-Seq_MC3T3_Mouse1.35514066
53ELK1_19687146_ChIP-ChIP_HELA_Human1.33522108
54TP53_22573176_ChIP-Seq_HFKS_Human1.33240034
55BP1_19119308_ChIP-ChIP_Hs578T_Human1.32462941
56IGF1R_20145208_ChIP-Seq_DFB_Human1.31306916
57RBPJ_22232070_ChIP-Seq_NCS_Mouse1.31255799
58POU5F1_18358816_ChIP-ChIP_MESCs_Mouse1.28351655
59RNF2_27304074_Chip-Seq_NSC_Mouse1.28078215
60MTF2_20144788_ChIP-Seq_MESCs_Mouse1.27831886
61TTF2_22483619_ChIP-Seq_HELA_Human1.27786141
62PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse1.27226685
63ELK1_22589737_ChIP-Seq_MCF10A_Human1.26867326
64SUZ12_20075857_ChIP-Seq_MESCs_Mouse1.25895772
65RCOR1_19997604_ChIP-ChIP_NEURONS_Mouse1.25355459
66RNF2_18974828_ChIP-Seq_MESCs_Mouse1.24197588
67EZH2_18974828_ChIP-Seq_MESCs_Mouse1.24197588
68REST_21632747_ChIP-Seq_MESCs_Mouse1.24062284
69SUZ12_27294783_Chip-Seq_ESCs_Mouse1.23063820
70SOX2_16153702_ChIP-ChIP_HESCs_Human1.21202906
71FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse1.20866189
72IRF1_19129219_ChIP-ChIP_H3396_Human1.20574514
73CRX_20693478_ChIP-Seq_ADULT_RETINA_Mouse1.20139670
74EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human1.20084916
75EZH2_27294783_Chip-Seq_ESCs_Mouse1.20012731
76THAP11_20581084_ChIP-Seq_MESCs_Mouse1.18890925
77FOXP2_21765815_ChIP-ChIP_NEURO2A_Mouse1.18322841
78TOP2B_26459242_ChIP-Seq_MCF-7_Human1.15818139
79* GABP_19822575_ChIP-Seq_HepG2_Human1.13825985
80VDR_23849224_ChIP-Seq_CD4+_Human1.13755270
81E2F1_18555785_ChIP-Seq_MESCs_Mouse1.12316569
82PCGF2_27294783_Chip-Seq_ESCs_Mouse1.12291683
83GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse1.11985467
84UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human1.09992312
85MYC_18358816_ChIP-ChIP_MESCs_Mouse1.09221341
86NANOG_16153702_ChIP-ChIP_HESCs_Human1.07834742
87POU5F1_16153702_ChIP-ChIP_HESCs_Human1.06005219
88IRF4_20064451_ChIP-Seq_CD4+T_Mouse1.05970333
89CBP_20019798_ChIP-Seq_JUKART_Human1.05970333
90FLI1_27457419_Chip-Seq_LIVER_Mouse1.05595056
91EWS_26573619_Chip-Seq_HEK293_Human1.04096837
92YY1_21170310_ChIP-Seq_MESCs_Mouse1.03894440
93TAL1_26923725_Chip-Seq_HPCs_Mouse1.03592513
94MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human1.02430591
95SALL1_21062744_ChIP-ChIP_HESCs_Human1.02415918
96FOXA1_27270436_Chip-Seq_PROSTATE_Human1.00605128
97FOXA1_25329375_ChIP-Seq_VCAP_Human1.00605128
98RNF2_16625203_ChIP-ChIP_MESCs_Mouse1.00161047
99JUN_21703547_ChIP-Seq_K562_Human0.99627216
100ELF1_17652178_ChIP-ChIP_JURKAT_Human0.99189839
101SMAD3_21741376_ChIP-Seq_EPCs_Human0.98957213
102REST_18959480_ChIP-ChIP_MESCs_Mouse0.98284169
103SOX2_19829295_ChIP-Seq_ESCs_Human0.97414547
104NANOG_19829295_ChIP-Seq_ESCs_Human0.97414547
105PAX6_23342162_ChIP-ChIP_BETA-FORBRAIN-LENS_Mouse0.97174636
106SUZ12_27294783_Chip-Seq_NPCs_Mouse0.97028343
107MYC_19030024_ChIP-ChIP_MESCs_Mouse0.95799285
108HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse0.95644805
109AR_20517297_ChIP-Seq_VCAP_Human0.95113055
110NANOG_18555785_Chip-Seq_ESCs_Mouse0.94733423
111NFE2_27457419_Chip-Seq_LIVER_Mouse0.93292420
112EZH2_27294783_Chip-Seq_NPCs_Mouse0.92990279
113YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse0.92816342
114* ASH2L_23239880_ChIP-Seq_MESCs_Mouse0.92751993
115AR_25329375_ChIP-Seq_VCAP_Human0.91996627
116BCAT_22108803_ChIP-Seq_LS180_Human0.91706630
117CEBPD_23245923_ChIP-Seq_MEFs_Mouse0.91533701
118PCGF2_27294783_Chip-Seq_NPCs_Mouse0.91460136
119XRN2_22483619_ChIP-Seq_HELA_Human0.91240486
120CDX2_19796622_ChIP-Seq_MESCs_Mouse0.90969215
121KLF5_20875108_ChIP-Seq_MESCs_Mouse0.90675446
122TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.90631224
123POU5F1_26923725_Chip-Seq_MESODERM_Mouse0.90631224
124SOX2_18555785_ChIP-Seq_MESCs_Mouse0.90542996
125RNF2_27304074_Chip-Seq_ESCs_Mouse0.90362902
126ZNF274_21170338_ChIP-Seq_K562_Hela0.90359485
127REST_19997604_ChIP-ChIP_NEURONS_Mouse0.90253088
128MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse0.89901037
129* EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse0.89888825
130ZFP42_18358816_ChIP-ChIP_MESCs_Mouse0.89266327
131HTT_18923047_ChIP-ChIP_STHdh_Human0.87934303
132* DCP1A_22483619_ChIP-Seq_HELA_Human0.87690170
133PRDM14_20953172_ChIP-Seq_ESCs_Human0.86739256
134* CMYC_18555785_Chip-Seq_ESCs_Mouse0.84160569
135ETV2_25802403_ChIP-Seq_MESCs_Mouse0.83874922
136SUZ12_18555785_Chip-Seq_ESCs_Mouse0.83807419
137NR3C1_23031785_ChIP-Seq_PC12_Mouse0.83405814
138EOMES_21245162_ChIP-Seq_HESCs_Human0.82828128
139PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human0.82603055
140CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons0.81669160
141TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.81644827

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0003880_abnormal_central_pattern4.99873672
2MP0001529_abnormal_vocalization4.19830923
3MP0001905_abnormal_dopamine_level3.67562722
4MP0009379_abnormal_foot_pigmentation3.05408626
5MP0000920_abnormal_myelination2.94457234
6MP0006276_abnormal_autonomic_nervous2.75581325
7MP0004270_analgesia2.66856643
8MP0002272_abnormal_nervous_system2.34982549
9MP0008877_abnormal_DNA_methylation2.22038856
10MP0004142_abnormal_muscle_tone2.19329572
11MP0002064_seizures2.16032557
12MP0002734_abnormal_mechanical_nocicepti2.15972804
13MP0003011_delayed_dark_adaptation2.12398282
14MP0001968_abnormal_touch/_nociception2.11735816
15MP0005423_abnormal_somatic_nervous2.11557109
16MP0003136_yellow_coat_color2.11538349
17MP0005171_absent_coat_pigmentation2.06677215
18MP0001440_abnormal_grooming_behavior2.04553594
19MP0003787_abnormal_imprinting2.01606910
20MP0002736_abnormal_nociception_after2.00416422
21MP0005409_darkened_coat_color1.98327530
22MP0009745_abnormal_behavioral_response1.96806389
23MP0002653_abnormal_ependyma_morphology1.96012342
24MP0004133_heterotaxia1.94186822
25MP0002735_abnormal_chemical_nociception1.93915110
26MP0003121_genomic_imprinting1.92022887
27MP0001970_abnormal_pain_threshold1.91734214
28MP0008995_early_reproductive_senescence1.90845502
29MP0005084_abnormal_gallbladder_morpholo1.83673525
30MP0005410_abnormal_fertilization1.83652634
31MP0003635_abnormal_synaptic_transmissio1.82822940
32MP0002638_abnormal_pupillary_reflex1.82778368
33MP0004742_abnormal_vestibular_system1.81695044
34MP0008058_abnormal_DNA_repair1.79668590
35MP0001486_abnormal_startle_reflex1.78338340
36MP0005394_taste/olfaction_phenotype1.78101790
37MP0005499_abnormal_olfactory_system1.78101790
38MP0002572_abnormal_emotion/affect_behav1.75199600
39MP0002733_abnormal_thermal_nociception1.73083808
40MP0000778_abnormal_nervous_system1.72705687
41MP0001986_abnormal_taste_sensitivity1.72610130
42MP0009046_muscle_twitch1.70854436
43MP0005379_endocrine/exocrine_gland_phen1.62955657
44MP0003329_amyloid_beta_deposits1.56274068
45MP0002163_abnormal_gland_morphology1.52815999
46MP0000372_irregular_coat_pigmentation1.50183386
47MP0001293_anophthalmia1.49681836
48MP0001984_abnormal_olfaction1.47406095
49MP0001188_hyperpigmentation1.46995697
50MP0002063_abnormal_learning/memory/cond1.46269084
51MP0004859_abnormal_synaptic_plasticity1.44509179
52MP0003950_abnormal_plasma_membrane1.44325394
53MP0002067_abnormal_sensory_capabilities1.41423077
54MP0003634_abnormal_glial_cell1.38730081
55MP0002234_abnormal_pharynx_morphology1.37843346
56MP0005386_behavior/neurological_phenoty1.36831045
57MP0004924_abnormal_behavior1.36831045
58MP0006072_abnormal_retinal_apoptosis1.36686985
59MP0001485_abnormal_pinna_reflex1.35070723
60MP0010386_abnormal_urinary_bladder1.33750613
61MP0002184_abnormal_innervation1.31476278
62MP0005645_abnormal_hypothalamus_physiol1.26701701
63MP0002229_neurodegeneration1.25333622
64MP0010030_abnormal_orbit_morphology1.24924419
65MP0001727_abnormal_embryo_implantation1.24024000
66MP0001501_abnormal_sleep_pattern1.23738823
67MP0000049_abnormal_middle_ear1.23018307
68MP0003122_maternal_imprinting1.19978161
69MP0002938_white_spotting1.19262102
70MP0000566_synostosis1.17387093
71MP0005408_hypopigmentation1.16816831
72MP0003890_abnormal_embryonic-extraembry1.15400152
73MP0002882_abnormal_neuron_morphology1.14922167
74MP0003786_premature_aging1.14865369
75MP0004145_abnormal_muscle_electrophysio1.14482976
76MP0005551_abnormal_eye_electrophysiolog1.13316192
77MP0002837_dystrophic_cardiac_calcinosis1.12218500
78MP0002752_abnormal_somatic_nervous1.10457001
79MP0001963_abnormal_hearing_physiology1.09676654
80MP0002102_abnormal_ear_morphology1.09300272
81MP0002066_abnormal_motor_capabilities/c1.08924414
82MP0000955_abnormal_spinal_cord1.08852693
83MP0008872_abnormal_physiological_respon1.06818014
84MP0006036_abnormal_mitochondrial_physio1.06648449
85MP0003195_calcinosis1.05337231
86MP0003690_abnormal_glial_cell1.03752978
87MP0004381_abnormal_hair_follicle1.03596035
88MP0008260_abnormal_autophagy1.03425531
89MP0002822_catalepsy1.03024264
90MP0003567_abnormal_fetal_cardiomyocyte1.01428852
91MP0002233_abnormal_nose_morphology0.99176185
92MP0002295_abnormal_pulmonary_circulatio0.97262781
93MP0005646_abnormal_pituitary_gland0.96837945
94MP0002277_abnormal_respiratory_mucosa0.96663477
95MP0003937_abnormal_limbs/digits/tail_de0.96364023
96MP0005187_abnormal_penis_morphology0.96312493
97MP0008875_abnormal_xenobiotic_pharmacok0.94183212
98MP0002282_abnormal_trachea_morphology0.94171566
99MP0002557_abnormal_social/conspecific_i0.94129473
100MP0009697_abnormal_copulation0.93597264
101MP0002876_abnormal_thyroid_physiology0.93526682
102MP0000647_abnormal_sebaceous_gland0.93092978
103MP0001502_abnormal_circadian_rhythm0.93009782
104MP0000631_abnormal_neuroendocrine_gland0.92128746
105MP0005391_vision/eye_phenotype0.91940770
106MP0002751_abnormal_autonomic_nervous0.90134615
107MP0001764_abnormal_homeostasis0.89977449
108MP0003119_abnormal_digestive_system0.89193574
109MP0004134_abnormal_chest_morphology0.88711773
110MP0000026_abnormal_inner_ear0.88678025
111MP0003315_abnormal_perineum_morphology0.88183134
112MP0003632_abnormal_nervous_system0.86643052
113MP0004215_abnormal_myocardial_fiber0.86168030
114MP0001286_abnormal_eye_development0.84937959
115MP0006035_abnormal_mitochondrial_morpho0.84343511
116MP0002210_abnormal_sex_determination0.84047754
117MP0003137_abnormal_impulse_conducting0.83859931
118MP0005253_abnormal_eye_physiology0.82920554
119MP0001324_abnormal_eye_pigmentation0.79066020
120MP0002090_abnormal_vision0.78788151
121MP0005451_abnormal_body_composition0.77866349
122MP0003631_nervous_system_phenotype0.76613527
123MP0004147_increased_porphyrin_level0.76022107
124MP0006292_abnormal_olfactory_placode0.74900297
125MP0001542_abnormal_bone_strength0.74290192
126MP0004043_abnormal_pH_regulation0.73654034
127MP0003938_abnormal_ear_development0.71764696
128MP0003718_maternal_effect0.71608168
129MP0001346_abnormal_lacrimal_gland0.69966472
130MP0001664_abnormal_digestion0.69280104
131MP0005195_abnormal_posterior_eye0.66680099
132MP0008569_lethality_at_weaning0.65698375
133MP0000462_abnormal_digestive_system0.65599395
134MP0008789_abnormal_olfactory_epithelium0.63669469
135MP0002152_abnormal_brain_morphology0.63393218
136MP0003186_abnormal_redox_activity0.61574128
137MP0006082_CNS_inflammation0.61413340
138MP0004036_abnormal_muscle_relaxation0.61358627
139MP0004885_abnormal_endolymph0.59629861

Predicted human phenotypes

RankGene SetZ-score
1Acute necrotizing encephalopathy (HP:0006965)5.97102979
2Mitochondrial inheritance (HP:0001427)5.20013391
3Abnormal mitochondria in muscle tissue (HP:0008316)5.19405952
4Progressive macrocephaly (HP:0004481)5.00830789
5Acute encephalopathy (HP:0006846)4.68846289
6Increased hepatocellular lipid droplets (HP:0006565)4.53903152
7Renal Fanconi syndrome (HP:0001994)4.36438528
8Hepatocellular necrosis (HP:0001404)4.19439756
9Congenital nonbullous ichthyosiform erythroderma (HP:0007479)4.18204744
10Increased CSF lactate (HP:0002490)4.11941082
11Increased serum pyruvate (HP:0003542)3.99355411
12Abnormality of glycolysis (HP:0004366)3.99355411
13Parakeratosis (HP:0001036)3.93148703
14Lipid accumulation in hepatocytes (HP:0006561)3.87068591
153-Methylglutaconic aciduria (HP:0003535)3.84574664
16Leukodystrophy (HP:0002415)3.66724440
17Atrophy/Degeneration involving the corticospinal tracts (HP:0007372)3.53449866
18Degeneration of the lateral corticospinal tracts (HP:0002314)3.53449866
19Muscle abnormality related to mitochondrial dysfunction (HP:0003800)3.46257960
20Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688)3.43244960
21True hermaphroditism (HP:0010459)3.36419597
22Pancreatic fibrosis (HP:0100732)3.35877120
23Hepatic necrosis (HP:0002605)3.32994340
24Pancreatic cysts (HP:0001737)3.31542052
25Sensory axonal neuropathy (HP:0003390)3.26656970
26Abnormality of midbrain morphology (HP:0002418)3.25643187
27Molar tooth sign on MRI (HP:0002419)3.25643187
28Optic disc pallor (HP:0000543)3.19102331
29Neurofibrillary tangles (HP:0002185)3.17485319
30Increased intramyocellular lipid droplets (HP:0012240)3.14116060
31Exertional dyspnea (HP:0002875)2.95592847
32Respiratory failure (HP:0002878)2.95028963
33Nephronophthisis (HP:0000090)2.94244314
34Myokymia (HP:0002411)2.89415895
35Hypothermia (HP:0002045)2.87680713
36Exercise intolerance (HP:0003546)2.85639919
37Abnormality of renal resorption (HP:0011038)2.84848890
38Medial flaring of the eyebrow (HP:0010747)2.77221539
39Neuroendocrine neoplasm (HP:0100634)2.75472754
40Cerebral hypomyelination (HP:0006808)2.74444401
41Abnormal activity of mitochondrial respiratory chain (HP:0011922)2.72969617
42Decreased activity of mitochondrial respiratory chain (HP:0008972)2.72969617
43Retinal dysplasia (HP:0007973)2.72432098
44Cerebral edema (HP:0002181)2.72249044
45Congenital, generalized hypertrichosis (HP:0004540)2.70792562
46Congenital ichthyosiform erythroderma (HP:0007431)2.68657490
47Pheochromocytoma (HP:0002666)2.60561622
48Abnormality of cells of the erythroid lineage (HP:0012130)2.57797594
49Gait imbalance (HP:0002141)2.51944714
50Abnormality of the labia minora (HP:0012880)2.51436303
51Lactic acidosis (HP:0003128)2.51327185
52Limb dystonia (HP:0002451)2.49531349
53Increased muscle lipid content (HP:0009058)2.44835344
54Vaginal atresia (HP:0000148)2.40390659
55Congenital primary aphakia (HP:0007707)2.39918939
56Hyperglycinemia (HP:0002154)2.39245305
57Genital tract atresia (HP:0001827)2.34578260
58Increased serum lactate (HP:0002151)2.33137341
59Abnormality of the corticospinal tract (HP:0002492)2.32631176
60Sclerocornea (HP:0000647)2.31320397
61Respiratory difficulties (HP:0002880)2.30625802
62Cerebral inclusion bodies (HP:0100314)2.30594870
63Abnormality of the renal medulla (HP:0100957)2.28998210
64Septo-optic dysplasia (HP:0100842)2.28886423
65Colon cancer (HP:0003003)2.28119474
66Peripheral hypomyelination (HP:0007182)2.26394085
67Cerebral hemorrhage (HP:0001342)2.24533047
68Abnormal ciliary motility (HP:0012262)2.23521009
69Nephrogenic diabetes insipidus (HP:0009806)2.22604013
70X-linked dominant inheritance (HP:0001423)2.19445267
71Atonic seizures (HP:0010819)2.19217853
72Methylmalonic aciduria (HP:0012120)2.17824894
73Lethargy (HP:0001254)2.15701461
74Reticulocytopenia (HP:0001896)2.15533713
75Respiratory insufficiency due to defective ciliary clearance (HP:0200073)2.15289951
76Abnormal respiratory motile cilium morphology (HP:0005938)2.13637689
77Abnormal respiratory epithelium morphology (HP:0012253)2.13637689
78Absent/shortened dynein arms (HP:0200106)2.13111778
79Dynein arm defect of respiratory motile cilia (HP:0012255)2.13111778
80Focal motor seizures (HP:0011153)2.07603503
81Abnormal number of erythroid precursors (HP:0012131)2.06582053
82Aplasia/Hypoplasia of the tongue (HP:0010295)2.02747889
83Abnormal respiratory motile cilium physiology (HP:0012261)2.02302722
84Abnormal pupillary function (HP:0007686)2.01457950
85Anencephaly (HP:0002323)1.98891208
86Supranuclear gaze palsy (HP:0000605)1.97423461
87CNS hypomyelination (HP:0003429)1.97354973
88Renal cortical cysts (HP:0000803)1.97130704
89Delusions (HP:0000746)1.96479789
90Male pseudohermaphroditism (HP:0000037)1.95608152
91Concave nail (HP:0001598)1.95564209
92Abnormality of the renal cortex (HP:0011035)1.93520960
93Abnormal hair whorl (HP:0010721)1.92693650
94Autoamputation (HP:0001218)1.92658014
95Congenital stationary night blindness (HP:0007642)1.92060300
96Degeneration of anterior horn cells (HP:0002398)1.91680720
97Abnormality of the anterior horn cell (HP:0006802)1.91680720
98Macrocytic anemia (HP:0001972)1.90443144
99Cystic liver disease (HP:0006706)1.87653678
100Aplastic anemia (HP:0001915)1.87430737
101Postaxial hand polydactyly (HP:0001162)1.87402659
102Postaxial foot polydactyly (HP:0001830)1.86484059
103Abolished electroretinogram (ERG) (HP:0000550)1.85939794
104Stenosis of the external auditory canal (HP:0000402)1.85442606
105Anophthalmia (HP:0000528)1.83797597
106Chronic hepatic failure (HP:0100626)1.83599033
107Spastic paraparesis (HP:0002313)1.83157087
108Emotional lability (HP:0000712)1.82965428
109Abnormal autonomic nervous system physiology (HP:0012332)1.81396115
110Abnormality of placental membranes (HP:0011409)1.80783003
111Amniotic constriction ring (HP:0009775)1.80783003
112Generalized aminoaciduria (HP:0002909)1.79674157
113Esotropia (HP:0000565)1.77841011
114Patchy hypopigmentation of hair (HP:0011365)1.77203340
115Optic nerve hypoplasia (HP:0000609)1.77091467
116Short tibia (HP:0005736)1.76380020
117Aplasia/hypoplasia of the uterus (HP:0008684)1.75517012
118Hyperphosphaturia (HP:0003109)1.75002410
119Occipital encephalocele (HP:0002085)1.74864929
120Akinesia (HP:0002304)1.74383268
121Intestinal atresia (HP:0011100)1.74348745
122Supernumerary spleens (HP:0009799)1.73216291
123Congenital hepatic fibrosis (HP:0002612)1.72008081
124Aplasia/Hypoplasia of the optic nerve (HP:0008058)1.68638733
125Type II lissencephaly (HP:0007260)1.68315239
126CNS demyelination (HP:0007305)1.67912372
127Adrenal hypoplasia (HP:0000835)1.66732609
128Progressive inability to walk (HP:0002505)1.65012922
129Aplasia/Hypoplasia of the lens (HP:0008063)1.62627427
130Poor suck (HP:0002033)1.60883365
131Rhinitis (HP:0012384)1.60592255
132Spastic gait (HP:0002064)1.58954740
133Abnormality of the axillary hair (HP:0100134)1.58044556
134Abnormality of secondary sexual hair (HP:0009888)1.58044556
135Postnatal microcephaly (HP:0005484)1.57773408
136Hypoplastic pelvis (HP:0008839)1.56738214
137Glycosuria (HP:0003076)1.56171100
138Abnormality of urine glucose concentration (HP:0011016)1.56171100
139Dialeptic seizures (HP:0011146)1.54868629
140Polyphagia (HP:0002591)1.54789757
141White forelock (HP:0002211)1.54417027
142Methylmalonic acidemia (HP:0002912)1.53764851

Predicted kinase interactions (KEA)

RankGene SetZ-score
1STK393.94406326
2ARAF3.05152532
3MAP4K22.90351784
4VRK22.87613757
5OXSR12.84783506
6MAP3K122.78590165
7MST42.54890376
8PNCK2.42502234
9TRIM282.40658061
10STK162.37218506
11BCR2.37075950
12MAPKAPK52.25058640
13TNIK2.24443949
14PBK2.21963593
15NME12.17135591
16CDK192.08742192
17LIMK12.06344412
18CASK2.04661297
19NME21.98279245
20MUSK1.94876773
21BCKDK1.91745250
22ZAK1.89024452
23WNK41.84589145
24GRK51.84396080
25NUAK11.81793105
26GRK71.66366842
27BMPR1B1.65661235
28CSNK1G31.65226551
29PINK11.50614047
30DYRK31.47147454
31DYRK21.45699686
32FGR1.45358029
33UHMK11.43743836
34INSRR1.40498716
35WEE11.35953914
36BUB11.35951108
37CAMK2B1.35887489
38CDC71.33548121
39ERBB31.32742681
40VRK11.32442261
41PKN11.32219893
42ADRBK21.26039378
43PLK31.25733782
44NTRK11.24313606
45MAPK131.19719749
46NEK11.17998050
47MARK11.17614771
48BMPR21.16567035
49CSNK1G11.13745982
50TESK21.13305506
51MYLK1.12757781
52CSNK1G21.12714218
53PIM21.11667192
54PLK41.10667316
55FRK1.10399292
56EPHB11.08454794
57CSNK1A1L1.05200555
58CAMK2D1.04882033
59NEK61.03456074
60MKNK21.03152918
61MET1.02263716
62EIF2AK31.00068168
63PLK20.99683405
64MAP2K70.99126958
65BRAF0.99108371
66ROCK20.98217306
67CAMK2A0.95788154
68NTRK30.86880542
69CAMK2G0.86183582
70EIF2AK10.83513518
71EPHA40.83372142
72CDK140.82627925
73TXK0.76332815
74KDR0.76197060
75PLK10.75385831
76PRKCE0.73227752
77IRAK20.73099168
78RIPK40.71775292
79TSSK60.71498394
80PTK2B0.71141264
81ADRBK10.70220429
82MAPK150.69869348
83TIE10.69032358
84MOS0.68320192
85CDK180.67289143
86CDK150.66614133
87ABL20.65080007
88CDK11A0.64177640
89RPS6KA50.63446145
90RAF10.62608664
91MAP3K90.62548933
92CDK50.60315784
93BRSK20.60261654
94FES0.58823313
95EPHB20.58014992
96KSR20.57940521
97GRK10.57517935
98NTRK20.55172786
99CSNK2A10.55040664
100OBSCN0.54328401
101RPS6KA40.53695758
102IRAK10.52748455
103MAP3K40.49817241
104CAMKK20.49548337
105CSNK2A20.49073684
106PDK20.48109558
107CSNK1A10.46833397
108AURKB0.46778312
109PASK0.46777748
110ATR0.46760519
111ILK0.46499861
112PAK30.45531301
113WNK10.45491806
114PAK10.45059820
115TAF10.44982491
116SRPK10.44075050
117PRKACA0.43787026
118ACVR1B0.43024291
119DAPK30.42542581
120TESK10.42133009
121CDK30.42000189
122TGFBR10.41992950
123PRPF4B0.41741716
124WNK30.41737994
125PRKCQ0.41495160
126MAP2K40.40760607
127PRKCG0.40542404
128TAOK30.40201090
129DAPK10.38537122
130STK38L0.38044615
131MINK10.37940099
132DYRK1B0.36717922
133PRKG10.34306790
134DYRK1A0.33510688
135TLK10.32201759
136PHKG10.31809168
137PHKG20.31809168
138CDK80.31007298
139MAP3K130.29046165
140IRAK40.29040349
141PAK60.28762759
142MKNK10.27969687

Predicted pathways (KEGG)

RankGene SetZ-score
1Oxidative phosphorylation_Homo sapiens_hsa001905.67915585
2Parkinsons disease_Homo sapiens_hsa050124.65602497
3Alzheimers disease_Homo sapiens_hsa050103.67598041
4Proteasome_Homo sapiens_hsa030503.39965917
5Ribosome_Homo sapiens_hsa030103.36820918
6Huntingtons disease_Homo sapiens_hsa050163.31421288
7Terpenoid backbone biosynthesis_Homo sapiens_hsa009003.30314397
8* Protein export_Homo sapiens_hsa030603.05369341
9Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049322.80317307
10Collecting duct acid secretion_Homo sapiens_hsa049662.42250072
11RNA polymerase_Homo sapiens_hsa030202.32276626
12Fatty acid elongation_Homo sapiens_hsa000622.16108106
13Cardiac muscle contraction_Homo sapiens_hsa042602.09101867
14Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005632.02175987
15Steroid biosynthesis_Homo sapiens_hsa001001.99873257
16Synthesis and degradation of ketone bodies_Homo sapiens_hsa000721.95192586
17Vibrio cholerae infection_Homo sapiens_hsa051101.82765316
18Homologous recombination_Homo sapiens_hsa034401.69732914
19Mismatch repair_Homo sapiens_hsa034301.69625692
20Ether lipid metabolism_Homo sapiens_hsa005651.62284420
21Propanoate metabolism_Homo sapiens_hsa006401.60063723
22SNARE interactions in vesicular transport_Homo sapiens_hsa041301.55305147
23Rheumatoid arthritis_Homo sapiens_hsa053231.39784403
24Serotonergic synapse_Homo sapiens_hsa047261.35495044
25Butanoate metabolism_Homo sapiens_hsa006501.35014483
26Valine, leucine and isoleucine degradation_Homo sapiens_hsa002801.34638897
27Fanconi anemia pathway_Homo sapiens_hsa034601.32054788
28Sulfur metabolism_Homo sapiens_hsa009201.31953719
29Nicotine addiction_Homo sapiens_hsa050331.29398597
30Synaptic vesicle cycle_Homo sapiens_hsa047211.28118248
31DNA replication_Homo sapiens_hsa030301.17286483
32Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030081.15979591
33Sphingolipid metabolism_Homo sapiens_hsa006001.15509330
34Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006301.14035051
35Retrograde endocannabinoid signaling_Homo sapiens_hsa047231.06671921
36Peroxisome_Homo sapiens_hsa041461.05616885
37Base excision repair_Homo sapiens_hsa034101.05282412
38Basal transcription factors_Homo sapiens_hsa030221.02307854
39Neuroactive ligand-receptor interaction_Homo sapiens_hsa040801.00803642
40Phototransduction_Homo sapiens_hsa047440.95894917
41Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.95072898
42GABAergic synapse_Homo sapiens_hsa047270.93998338
43RNA transport_Homo sapiens_hsa030130.93560417
44Maturity onset diabetes of the young_Homo sapiens_hsa049500.92192407
45Vasopressin-regulated water reabsorption_Homo sapiens_hsa049620.91908592
46Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.91351008
47Phagosome_Homo sapiens_hsa041450.91080194
48Tryptophan metabolism_Homo sapiens_hsa003800.88784355
49Nitrogen metabolism_Homo sapiens_hsa009100.87374255
50Linoleic acid metabolism_Homo sapiens_hsa005910.86218833
51Regulation of autophagy_Homo sapiens_hsa041400.85446806
52Glutamatergic synapse_Homo sapiens_hsa047240.82599745
53Taste transduction_Homo sapiens_hsa047420.81132898
54Pyrimidine metabolism_Homo sapiens_hsa002400.80204800
55Chemical carcinogenesis_Homo sapiens_hsa052040.79466105
56Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.78955348
57Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001300.78090981
58Morphine addiction_Homo sapiens_hsa050320.77954449
59Cysteine and methionine metabolism_Homo sapiens_hsa002700.77838559
60Caffeine metabolism_Homo sapiens_hsa002320.76058818
61Dopaminergic synapse_Homo sapiens_hsa047280.75460073
62Arachidonic acid metabolism_Homo sapiens_hsa005900.75441965
63Primary bile acid biosynthesis_Homo sapiens_hsa001200.72274983
64Long-term depression_Homo sapiens_hsa047300.72124284
65Amphetamine addiction_Homo sapiens_hsa050310.71361818
66Cocaine addiction_Homo sapiens_hsa050300.70852140
67Autoimmune thyroid disease_Homo sapiens_hsa053200.69038506
68Vitamin B6 metabolism_Homo sapiens_hsa007500.67647411
69Metabolic pathways_Homo sapiens_hsa011000.65778173
70Purine metabolism_Homo sapiens_hsa002300.65730085
71Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.63965671
72Selenocompound metabolism_Homo sapiens_hsa004500.62534664
73One carbon pool by folate_Homo sapiens_hsa006700.62379966
74Circadian entrainment_Homo sapiens_hsa047130.61776334
75Axon guidance_Homo sapiens_hsa043600.61222418
76Ascorbate and aldarate metabolism_Homo sapiens_hsa000530.61189997
77beta-Alanine metabolism_Homo sapiens_hsa004100.60675600
78Glutathione metabolism_Homo sapiens_hsa004800.60660714
79alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.60566930
80Graft-versus-host disease_Homo sapiens_hsa053320.59742761
81Retinol metabolism_Homo sapiens_hsa008300.56152364
82Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009700.55447307
83Cytosolic DNA-sensing pathway_Homo sapiens_hsa046230.54544531
84Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.51159830
85Cholinergic synapse_Homo sapiens_hsa047250.50875478
86Pentose and glucuronate interconversions_Homo sapiens_hsa000400.50696285
87Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.49628495
88Taurine and hypotaurine metabolism_Homo sapiens_hsa004300.47528526
89Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.47080258
90Steroid hormone biosynthesis_Homo sapiens_hsa001400.46654408
91Asthma_Homo sapiens_hsa053100.46227386
92Basal cell carcinoma_Homo sapiens_hsa052170.45339477
93Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010400.44279488
94Histidine metabolism_Homo sapiens_hsa003400.43396422
95Alcoholism_Homo sapiens_hsa050340.43196742
96Sulfur relay system_Homo sapiens_hsa041220.42922988
97Hedgehog signaling pathway_Homo sapiens_hsa043400.42342370
98Fatty acid degradation_Homo sapiens_hsa000710.40953454
99Allograft rejection_Homo sapiens_hsa053300.40290494
100Tyrosine metabolism_Homo sapiens_hsa003500.40047670
101Olfactory transduction_Homo sapiens_hsa047400.39888339
102Oocyte meiosis_Homo sapiens_hsa041140.39175554
103Renin secretion_Homo sapiens_hsa049240.39169694
104Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.38770905
105Long-term potentiation_Homo sapiens_hsa047200.37844712
106Vascular smooth muscle contraction_Homo sapiens_hsa042700.37441287
107Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.36705114
108Nucleotide excision repair_Homo sapiens_hsa034200.36381188
109Spliceosome_Homo sapiens_hsa030400.35330434
110Fatty acid metabolism_Homo sapiens_hsa012120.35065756
111Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.33730146
112Salivary secretion_Homo sapiens_hsa049700.33546523
113Pyruvate metabolism_Homo sapiens_hsa006200.32171805
114Calcium signaling pathway_Homo sapiens_hsa040200.32033741
1152-Oxocarboxylic acid metabolism_Homo sapiens_hsa012100.31889887
116Sphingolipid signaling pathway_Homo sapiens_hsa040710.30612935
117Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047500.30077550
118Carbon metabolism_Homo sapiens_hsa012000.29318308
119Lysosome_Homo sapiens_hsa041420.27845430
120Drug metabolism - cytochrome P450_Homo sapiens_hsa009820.27659242
121Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.27021755
122Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.24983864
123Folate biosynthesis_Homo sapiens_hsa007900.24757930
124Ras signaling pathway_Homo sapiens_hsa040140.23744457
125Type I diabetes mellitus_Homo sapiens_hsa049400.22001574
126Arginine and proline metabolism_Homo sapiens_hsa003300.20639283
127RNA degradation_Homo sapiens_hsa030180.20420740
128Renal cell carcinoma_Homo sapiens_hsa052110.20357749
129Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.19746621
130Ovarian steroidogenesis_Homo sapiens_hsa049130.17980434
131Oxytocin signaling pathway_Homo sapiens_hsa049210.17772828
132Gastric acid secretion_Homo sapiens_hsa049710.17580403
133Epstein-Barr virus infection_Homo sapiens_hsa051690.17199041
134Non-homologous end-joining_Homo sapiens_hsa034500.16838200
135Insulin secretion_Homo sapiens_hsa049110.16434311
136Gap junction_Homo sapiens_hsa045400.16033609
137Glycerophospholipid metabolism_Homo sapiens_hsa005640.15342304
138African trypanosomiasis_Homo sapiens_hsa051430.14828341
139Malaria_Homo sapiens_hsa051440.14449164
140Endocytosis_Homo sapiens_hsa041440.11734225
141Pancreatic secretion_Homo sapiens_hsa049720.11413788

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