SRGAP3

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1synaptic vesicle maturation (GO:0016188)6.05895223
2regulation of short-term neuronal synaptic plasticity (GO:0048172)6.05722320
3locomotory exploration behavior (GO:0035641)6.02387755
4positive regulation of excitatory postsynaptic membrane potential (GO:2000463)5.60335563
5vocalization behavior (GO:0071625)5.53846599
6positive regulation of calcium ion-dependent exocytosis (GO:0045956)5.39106190
7pyrimidine nucleobase catabolic process (GO:0006208)5.28297381
8regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor act5.25412188
9synaptic vesicle exocytosis (GO:0016079)5.18185660
10glutamate secretion (GO:0014047)5.10864667
11synaptic vesicle docking involved in exocytosis (GO:0016081)4.99894124
12regulation of synaptic vesicle exocytosis (GO:2000300)4.92231444
13regulation of glutamate receptor signaling pathway (GO:1900449)4.85747359
14layer formation in cerebral cortex (GO:0021819)4.81001269
15protein localization to synapse (GO:0035418)4.71546892
16ionotropic glutamate receptor signaling pathway (GO:0035235)4.69055282
17exploration behavior (GO:0035640)4.64146495
18neuron cell-cell adhesion (GO:0007158)4.53642463
19dendritic spine morphogenesis (GO:0060997)4.51421867
20regulation of synapse structural plasticity (GO:0051823)4.45080810
21neurotransmitter secretion (GO:0007269)4.41587673
22epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287)4.35968907
23regulation of neuronal synaptic plasticity (GO:0048168)4.35874048
24regulation of synaptic vesicle transport (GO:1902803)4.32204703
25regulation of long-term neuronal synaptic plasticity (GO:0048169)4.31611407
26nucleobase catabolic process (GO:0046113)4.29159518
27behavioral response to nicotine (GO:0035095)4.28861927
28synaptic transmission, glutamatergic (GO:0035249)4.20671493
29glutamate receptor signaling pathway (GO:0007215)4.16617186
30gamma-aminobutyric acid transport (GO:0015812)4.08204762
31neurotransmitter-gated ion channel clustering (GO:0072578)4.07488777
32positive regulation of synapse maturation (GO:0090129)3.99818560
33neuronal action potential propagation (GO:0019227)3.99642038
34regulation of N-methyl-D-aspartate selective glutamate receptor activity (GO:2000310)3.95610446
35cellular potassium ion homeostasis (GO:0030007)3.88542639
36sodium ion export (GO:0071436)3.83981908
37neuron-neuron synaptic transmission (GO:0007270)3.83825168
38proline transport (GO:0015824)3.82867296
39cerebellar Purkinje cell differentiation (GO:0021702)3.81009792
40dendrite morphogenesis (GO:0048813)3.79876548
41long-term memory (GO:0007616)3.79618387
42neuron recognition (GO:0008038)3.79305549
43central nervous system myelination (GO:0022010)3.68993962
44axon ensheathment in central nervous system (GO:0032291)3.68993962
45positive regulation of membrane potential (GO:0045838)3.68869852
46axonal fasciculation (GO:0007413)3.67173994
47epithelial cilium movement (GO:0003351)3.66450572
48regulation of excitatory postsynaptic membrane potential (GO:0060079)3.64974289
49auditory behavior (GO:0031223)3.63304772
50regulation of inhibitory postsynaptic membrane potential (GO:0060080)3.61550055
51membrane depolarization during cardiac muscle cell action potential (GO:0086012)3.59063939
52cell migration in hindbrain (GO:0021535)3.58300561
53retinal ganglion cell axon guidance (GO:0031290)3.56002435
54synaptic vesicle endocytosis (GO:0048488)3.52148048
55postsynaptic membrane organization (GO:0001941)3.51475287
56neurotransmitter transport (GO:0006836)3.51076676
57regulation of postsynaptic membrane potential (GO:0060078)3.48629560
58regulation of dendritic spine morphogenesis (GO:0061001)3.46463720
59neuromuscular process controlling balance (GO:0050885)3.46045611
60cerebellar granule cell differentiation (GO:0021707)3.42897418
61cilium movement (GO:0003341)3.41128138
62regulation of synaptic plasticity (GO:0048167)3.40850749
63regulation of neurotransmitter secretion (GO:0046928)3.39974796
64cell communication by electrical coupling (GO:0010644)3.37834208
65response to auditory stimulus (GO:0010996)3.37073086
66central nervous system projection neuron axonogenesis (GO:0021952)3.36382604
67innervation (GO:0060384)3.32659808
68cell communication by electrical coupling involved in cardiac conduction (GO:0086064)3.32634212
69G-protein coupled glutamate receptor signaling pathway (GO:0007216)3.29822062
70transmission of nerve impulse (GO:0019226)3.29153040
71positive regulation of potassium ion transmembrane transporter activity (GO:1901018)3.28989832
72positive regulation of synaptic transmission, glutamatergic (GO:0051968)3.28011849
73activation of protein kinase A activity (GO:0034199)3.25769683
74regulation of neurotransmitter levels (GO:0001505)3.23842966
75regulation of synaptic transmission, glutamatergic (GO:0051966)3.22516053
76regulation of respiratory gaseous exchange by neurological system process (GO:0002087)3.17472651
77limb bud formation (GO:0060174)3.17006461
78establishment of nucleus localization (GO:0040023)3.16924858
79long-term synaptic potentiation (GO:0060291)3.16580697
80dendritic spine organization (GO:0097061)3.16394307
81startle response (GO:0001964)3.16118492
82positive regulation of synaptic transmission, GABAergic (GO:0032230)3.14956056
83glycine transport (GO:0015816)3.13993175
84gamma-aminobutyric acid signaling pathway (GO:0007214)3.12408676
85establishment of mitochondrion localization (GO:0051654)3.12005636
86neuronal ion channel clustering (GO:0045161)3.11790751
87synapse assembly (GO:0007416)3.11306651
88regulation of neurotransmitter transport (GO:0051588)3.11079534
89membrane depolarization during action potential (GO:0086010)3.10207797
90positive regulation of dendritic spine morphogenesis (GO:0061003)3.09602608
91regulation of synapse maturation (GO:0090128)3.08967980
92response to pheromone (GO:0019236)3.08921423
93prepulse inhibition (GO:0060134)3.08746456
94cerebral cortex radially oriented cell migration (GO:0021799)3.07977657
95membrane hyperpolarization (GO:0060081)3.07894791
96spinal cord development (GO:0021510)3.07497141
97nonmotile primary cilium assembly (GO:0035058)3.05885013
98regulation of vesicle fusion (GO:0031338)3.05584765
99positive regulation of dendritic spine development (GO:0060999)3.05562580
100protein polyglutamylation (GO:0018095)3.03290802
101membrane depolarization (GO:0051899)3.03166496
102positive regulation of synapse assembly (GO:0051965)3.02826913
103regulation of ARF protein signal transduction (GO:0032012)3.02460931
104learning (GO:0007612)3.02233228
105cilium or flagellum-dependent cell motility (GO:0001539)3.02225869
106neuromuscular synaptic transmission (GO:0007274)3.01281910
107positive regulation of neurotransmitter secretion (GO:0001956)3.00713357
108regulation of atrial cardiac muscle cell membrane depolarization (GO:0060371)2.99584052
109presynaptic membrane assembly (GO:0097105)2.97936072
110mechanosensory behavior (GO:0007638)2.97876214
111negative regulation of synaptic transmission, GABAergic (GO:0032229)2.97849817
112somite development (GO:0061053)2.95524873
113presynaptic membrane organization (GO:0097090)2.95053669
114adult walking behavior (GO:0007628)2.95003221
115L-amino acid import (GO:0043092)2.94699972
116regulation of dendritic spine development (GO:0060998)2.93506360
117positive regulation of neurotransmitter transport (GO:0051590)2.93484677
118behavioral defense response (GO:0002209)2.91454024
119behavioral fear response (GO:0001662)2.91454024
120neuromuscular process (GO:0050905)2.91293859
121synapse organization (GO:0050808)2.88005757
122neuronal stem cell maintenance (GO:0097150)2.87689711
123neuronal action potential (GO:0019228)2.87441436
124axonemal dynein complex assembly (GO:0070286)2.84278546
125forebrain neuron differentiation (GO:0021879)2.81340879
126calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules (GO:0016339)2.79065581
127intraciliary transport (GO:0042073)2.76002775
128central nervous system neuron axonogenesis (GO:0021955)2.74283201
129negative regulation of cytosolic calcium ion concentration (GO:0051481)2.74218057
130positive regulation of action potential (GO:0045760)2.71786760
131negative regulation of axon extension (GO:0030517)2.71470593
132negative regulation of synaptic transmission, glutamatergic (GO:0051967)2.71029462
133cochlea development (GO:0090102)2.69730005
134protein localization to cilium (GO:0061512)2.69267016
135axoneme assembly (GO:0035082)2.68761410
136negative regulation of axon guidance (GO:1902668)2.67623194
137negative regulation of oligodendrocyte differentiation (GO:0048715)2.67578971
138substrate-independent telencephalic tangential interneuron migration (GO:0021843)2.66511193
139substrate-independent telencephalic tangential migration (GO:0021826)2.66511193
140regulation of cilium movement (GO:0003352)2.65713360
141negative regulation of astrocyte differentiation (GO:0048712)2.64538550
142regulation of respiratory system process (GO:0044065)2.64427527
143regulation of action potential (GO:0098900)2.60996827
144cilium organization (GO:0044782)2.60728056
145regulation of microtubule-based movement (GO:0060632)2.59909449
146regulation of synapse assembly (GO:0051963)2.57879989
147cilium assembly (GO:0042384)2.57457712
148glycosphingolipid biosynthetic process (GO:0006688)2.57375038
149behavioral response to ethanol (GO:0048149)2.56479683
150appendage development (GO:0048736)2.56255180
151limb development (GO:0060173)2.56255180

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1EZH2_22144423_ChIP-Seq_EOC_Human5.80294639
2* GBX2_23144817_ChIP-Seq_PC3_Human3.12896344
3JARID2_20064375_ChIP-Seq_MESCs_Mouse3.02963262
4SUZ12_18692474_ChIP-Seq_MESCs_Mouse3.02719620
5SUZ12_18555785_ChIP-Seq_MESCs_Mouse2.98253269
6EZH2_18974828_ChIP-Seq_MESCs_Mouse2.76866171
7RNF2_18974828_ChIP-Seq_MESCs_Mouse2.76866171
8* REST_21632747_ChIP-Seq_MESCs_Mouse2.65269130
9JARID2_20075857_ChIP-Seq_MESCs_Mouse2.64080014
10* DROSHA_22980978_ChIP-Seq_HELA_Human2.62972582
11EZH2_27304074_Chip-Seq_ESCs_Mouse2.54655584
12SUZ12_16625203_ChIP-ChIP_MESCs_Mouse2.51540335
13SUZ12_18974828_ChIP-Seq_MESCs_Mouse2.50175672
14MTF2_20144788_ChIP-Seq_MESCs_Mouse2.46586551
15RARB_27405468_Chip-Seq_BRAIN_Mouse2.46099905
16SUZ12_20075857_ChIP-Seq_MESCs_Mouse2.44805966
17SUZ12_18692474_ChIP-Seq_MEFs_Mouse2.39053842
18EZH2_27294783_Chip-Seq_ESCs_Mouse2.33572606
19RNF2_27304074_Chip-Seq_ESCs_Mouse2.30606160
20SUZ12_27294783_Chip-Seq_ESCs_Mouse2.28796088
21EED_16625203_ChIP-ChIP_MESCs_Mouse2.26483086
22ZFP322A_24550733_ChIP-Seq_MESCs_Mouse2.17633027
23VDR_22108803_ChIP-Seq_LS180_Human2.15931271
24REST_18959480_ChIP-ChIP_MESCs_Mouse2.12947218
25CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons2.10383237
26* EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse2.09753531
27GLI1_17442700_ChIP-ChIP_MESCs_Mouse2.09161686
28IKZF1_21737484_ChIP-ChIP_HCT116_Human1.98371941
29TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.98328890
30MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human1.97388590
31NR4A2_19515692_ChIP-ChIP_MN9D_Mouse1.95166116
32AR_21572438_ChIP-Seq_LNCaP_Human1.86589617
33POU3F2_20337985_ChIP-ChIP_501MEL_Human1.76051381
34CEBPD_23245923_ChIP-Seq_MEFs_Mouse1.72991017
35HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse1.67622085
36FUS_26573619_Chip-Seq_HEK293_Human1.67147959
37RBPJ_22232070_ChIP-Seq_NCS_Mouse1.64552592
38CTBP2_25329375_ChIP-Seq_LNCAP_Human1.63185786
39* SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.62138358
40ERG_21242973_ChIP-ChIP_JURKAT_Human1.60902669
41* SMAD4_21799915_ChIP-Seq_A2780_Human1.53388372
42PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.44780725
43RING1B_27294783_Chip-Seq_ESCs_Mouse1.42554475
44CTBP1_25329375_ChIP-Seq_LNCAP_Human1.42488950
45PHC1_16625203_ChIP-ChIP_MESCs_Mouse1.41829407
46EWS_26573619_Chip-Seq_HEK293_Human1.41773953
47MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse1.37138502
48RNF2_16625203_ChIP-ChIP_MESCs_Mouse1.34077609
49ZNF274_21170338_ChIP-Seq_K562_Hela1.33299635
50CBX2_27304074_Chip-Seq_ESCs_Mouse1.29377553
51SALL1_21062744_ChIP-ChIP_HESCs_Human1.29219798
52SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.28667349
53* SOX2_21211035_ChIP-Seq_LN229_Gbm1.27954471
54RING1B_27294783_Chip-Seq_NPCs_Mouse1.27820817
55AR_19668381_ChIP-Seq_PC3_Human1.27424674
56ER_23166858_ChIP-Seq_MCF-7_Human1.26318752
57* RCOR3_21632747_ChIP-Seq_MESCs_Mouse1.26073708
58UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human1.25992332
59WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse1.24460909
60KDM2B_26808549_Chip-Seq_K562_Human1.24385310
61* WT1_25993318_ChIP-Seq_PODOCYTE_Human1.24345865
62ZFP281_18757296_ChIP-ChIP_E14_Mouse1.23348578
63TAF15_26573619_Chip-Seq_HEK293_Human1.22305421
64NR3C1_23031785_ChIP-Seq_PC12_Mouse1.21730045
65DNAJC2_21179169_ChIP-ChIP_NT2_Human1.21486512
66BCAT_22108803_ChIP-Seq_LS180_Human1.20345007
67MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human1.19464876
68* SMAD3_21741376_ChIP-Seq_EPCs_Human1.18896906
69AR_25329375_ChIP-Seq_VCAP_Human1.18189539
70SMAD_19615063_ChIP-ChIP_OVARY_Human1.17840481
71P300_19829295_ChIP-Seq_ESCs_Human1.17557618
72STAT3_23295773_ChIP-Seq_U87_Human1.17016863
73ZFP57_27257070_Chip-Seq_ESCs_Mouse1.15363118
74KLF4_25985364_ChIP-Seq_ATHEROSCLEROSIS_LESION_Mouse1.14482696
75TFAP2C_20629094_ChIP-Seq_MCF-7_Human1.14249264
76P53_22127205_ChIP-Seq_FIBROBLAST_Human1.13913224
77IRF4_20064451_ChIP-Seq_CD4+T_Mouse1.13878647
78CBP_20019798_ChIP-Seq_JUKART_Human1.13878647
79ARNT_22903824_ChIP-Seq_MCF-7_Human1.13679270
80YAP1_20516196_ChIP-Seq_MESCs_Mouse1.12460562
81* ZNF217_24962896_ChIP-Seq_MCF-7_Human1.11904251
82OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.08354896
83RNF2_27304074_Chip-Seq_NSC_Mouse1.07820857
84EGR1_20690147_ChIP-Seq_ERYTHROLEUKEMIA_Human1.07704434
85AHR_22903824_ChIP-Seq_MCF-7_Human1.07516940
86TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human1.07113788
87POU5F1_16153702_ChIP-ChIP_HESCs_Human1.06382297
88TOP2B_26459242_ChIP-Seq_MCF-7_Human1.06256120
89STAT3_24763339_ChIP-Seq_IMN-ESCs_Mouse1.05419706
90TCF3_18467660_ChIP-ChIP_MESCs_Mouse1.05413535
91LMO2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.05083535
92SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.04801002
93TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse1.04659780
94TCF4_23295773_ChIP-Seq_U87_Human1.02932625
95SMAD3_21741376_ChIP-Seq_ESCs_Human1.01269986
96* PIAS1_25552417_ChIP-Seq_VCAP_Human1.00134404
97NANOG_18555785_Chip-Seq_ESCs_Mouse0.99967428
98FLI1_27457419_Chip-Seq_LIVER_Mouse0.99603229
99* ZFP281_27345836_Chip-Seq_ESCs_Mouse0.99136328
100IGF1R_20145208_ChIP-Seq_DFB_Human0.98893370
101VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human0.98700410
102BMI1_23680149_ChIP-Seq_NPCS_Mouse0.98145533
103* SMAD4_21741376_ChIP-Seq_HESCs_Human0.98065543
104* MEIS1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse0.97835912
105TCF4_22108803_ChIP-Seq_LS180_Human0.97488706
106RCOR2_21632747_ChIP-Seq_MESCs_Mouse0.97414244
107NR3C1_21868756_ChIP-Seq_MCF10A_Human0.97172988
108CDX2_19796622_ChIP-Seq_MESCs_Mouse0.97091307
109IRF1_19129219_ChIP-ChIP_H3396_Human0.96657988
110GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.95486319
111POU5F1_26923725_Chip-Seq_MESODERM_Mouse0.95332193
112TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.95332193
113KDM2B_26808549_Chip-Seq_REH_Human0.95039151
114* AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human0.94839627
115KLF5_20875108_ChIP-Seq_MESCs_Mouse0.94547830
116* SMAD3_22036565_ChIP-Seq_ESCs_Mouse0.93441087
117SOX9_26525672_Chip-Seq_HEART_Mouse0.93346702
118* OLIG2_26023283_ChIP-Seq_AINV15_Mouse0.93144025
119FLI1_21867929_ChIP-Seq_TH2_Mouse0.91883443
120GATA2_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.90893111
121TP53_16413492_ChIP-PET_HCT116_Human0.90878416
122TEAD4_22529382_ChIP-Seq_TROPHECTODERM_Mouse0.90242073
123SMAD3_21741376_ChIP-Seq_HESCs_Human0.89204985
124* RUNX2_22187159_ChIP-Seq_PCA_Human0.89119137
125TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.87663529
126CEBPB_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.87169841
127PRDM14_20953172_ChIP-Seq_ESCs_Human0.86810612
128RXR_22108803_ChIP-Seq_LS180_Human0.86345453
129* DMRT1_23473982_ChIP-Seq_TESTES_Mouse0.85825812

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0004859_abnormal_synaptic_plasticity6.78255490
2MP0003880_abnormal_central_pattern4.29404779
3MP0003635_abnormal_synaptic_transmissio4.08977507
4MP0004270_analgesia3.80510541
5MP0005423_abnormal_somatic_nervous3.29348010
6MP0002063_abnormal_learning/memory/cond3.27103876
7MP0009745_abnormal_behavioral_response3.19525333
8MP0009046_muscle_twitch3.08156044
9MP0002064_seizures2.99998751
10MP0001968_abnormal_touch/_nociception2.87662916
11MP0002572_abnormal_emotion/affect_behav2.68887037
12MP0002734_abnormal_mechanical_nocicepti2.67017958
13MP0001486_abnormal_startle_reflex2.56349841
14MP0002272_abnormal_nervous_system2.46008577
15MP0000778_abnormal_nervous_system2.31259980
16MP0002735_abnormal_chemical_nociception2.24411927
17MP0003136_yellow_coat_color2.16830342
18MP0002736_abnormal_nociception_after2.15459000
19MP0004858_abnormal_nervous_system2.09630585
20MP0002184_abnormal_innervation2.07421305
21MP0009780_abnormal_chondrocyte_physiolo2.07210663
22MP0001440_abnormal_grooming_behavior2.02332080
23MP0002733_abnormal_thermal_nociception2.00177983
24MP0008569_lethality_at_weaning1.99739460
25MP0001501_abnormal_sleep_pattern1.98614710
26MP0004811_abnormal_neuron_physiology1.96398065
27MP0002067_abnormal_sensory_capabilities1.93958434
28MP0002822_catalepsy1.93329007
29MP0001970_abnormal_pain_threshold1.87013983
30MP0002557_abnormal_social/conspecific_i1.86151142
31MP0000566_synostosis1.81491672
32MP0004885_abnormal_endolymph1.80047305
33MP0000955_abnormal_spinal_cord1.73141720
34MP0005646_abnormal_pituitary_gland1.69905556
35MP0003879_abnormal_hair_cell1.68332537
36MP0004924_abnormal_behavior1.66604816
37MP0005386_behavior/neurological_phenoty1.66604816
38MP0003329_amyloid_beta_deposits1.64088953
39MP0004133_heterotaxia1.62273594
40MP0002102_abnormal_ear_morphology1.60397036
41MP0006276_abnormal_autonomic_nervous1.60127790
42MP0000569_abnormal_digit_pigmentation1.58774144
43MP0002882_abnormal_neuron_morphology1.57360285
44MP0002909_abnormal_adrenal_gland1.56175350
45MP0001984_abnormal_olfaction1.55873099
46MP0008877_abnormal_DNA_methylation1.54620342
47MP0005645_abnormal_hypothalamus_physiol1.53952342
48MP0003121_genomic_imprinting1.51616473
49MP0003787_abnormal_imprinting1.46416698
50MP0002066_abnormal_motor_capabilities/c1.41544797
51MP0002152_abnormal_brain_morphology1.27473586
52MP0005394_taste/olfaction_phenotype1.27396867
53MP0005499_abnormal_olfactory_system1.27396867
54MP0003633_abnormal_nervous_system1.26205780
55MP0005253_abnormal_eye_physiology1.26048441
56MP0001502_abnormal_circadian_rhythm1.25269962
57MP0002938_white_spotting1.18946097
58MP0002234_abnormal_pharynx_morphology1.12182342
59MP0000049_abnormal_middle_ear1.10743910
60MP0004742_abnormal_vestibular_system1.09470906
61MP0003631_nervous_system_phenotype1.09451329
62MP0003890_abnormal_embryonic-extraembry1.06243345
63MP0005551_abnormal_eye_electrophysiolog1.05289051
64MP0004142_abnormal_muscle_tone1.04434230
65MP0003122_maternal_imprinting1.01429753
66MP0001188_hyperpigmentation0.98700112
67MP0002751_abnormal_autonomic_nervous0.97576036
68MP0002229_neurodegeneration0.97069132
69MP0000631_abnormal_neuroendocrine_gland0.96450623
70MP0005195_abnormal_posterior_eye0.96281211
71MP0002069_abnormal_eating/drinking_beha0.93919128
72MP0001905_abnormal_dopamine_level0.93747330
73MP0001177_atelectasis0.93618400
74MP0001986_abnormal_taste_sensitivity0.93520382
75MP0003119_abnormal_digestive_system0.92828344
76MP0002928_abnormal_bile_duct0.92304282
77MP0003634_abnormal_glial_cell0.92112278
78MP0004145_abnormal_muscle_electrophysio0.91840370
79MP0002752_abnormal_somatic_nervous0.90096463
80MP0001293_anophthalmia0.89677074
81MP0001963_abnormal_hearing_physiology0.88603749
82MP0003690_abnormal_glial_cell0.88040245
83MP0003283_abnormal_digestive_organ0.87527662
84MP0003632_abnormal_nervous_system0.86340142
85MP0002249_abnormal_larynx_morphology0.85559946
86MP0003861_abnormal_nervous_system0.85526114
87MP0001485_abnormal_pinna_reflex0.84577080
88MP0001529_abnormal_vocalization0.83695797
89MP0000751_myopathy0.83081426
90MP0003011_delayed_dark_adaptation0.82646525
91MP0008872_abnormal_physiological_respon0.82313433
92MP0004043_abnormal_pH_regulation0.82307931
93MP0001299_abnormal_eye_distance/0.80391741
94MP0004147_increased_porphyrin_level0.79605753
95MP0003878_abnormal_ear_physiology0.79506101
96MP0005377_hearing/vestibular/ear_phenot0.79506101
97MP0005391_vision/eye_phenotype0.77878957
98MP0002233_abnormal_nose_morphology0.77705844
99MP0003937_abnormal_limbs/digits/tail_de0.77099135
100MP0008961_abnormal_basal_metabolism0.76203938
101MP0000920_abnormal_myelination0.75976461
102MP0004085_abnormal_heartbeat0.75676662
103MP0008789_abnormal_olfactory_epithelium0.75028482
104MP0002653_abnormal_ependyma_morphology0.74489451
105MP0002090_abnormal_vision0.73516652
106MP0000534_abnormal_ureter_morphology0.73115041
107MP0008874_decreased_physiological_sensi0.72701202
108MP0005187_abnormal_penis_morphology0.69850161
109MP0003137_abnormal_impulse_conducting0.65374760
110MP0000026_abnormal_inner_ear0.63786780
111MP0003075_altered_response_to0.62959455
112MP0006292_abnormal_olfactory_placode0.62786903
113MP0005623_abnormal_meninges_morphology0.62529701
114MP0010769_abnormal_survival0.62391525
115MP0002638_abnormal_pupillary_reflex0.61736073
116MP0004233_abnormal_muscle_weight0.61681626
117MP0001943_abnormal_respiration0.61291279
118MP0006072_abnormal_retinal_apoptosis0.61140201
119MP0002082_postnatal_lethality0.60146331
120MP0010770_preweaning_lethality0.60146331
121MP0003938_abnormal_ear_development0.60044564
122MP0000604_amyloidosis0.59936792
123MP0010768_mortality/aging0.58302448
124MP0010386_abnormal_urinary_bladder0.57871965
125MP0005535_abnormal_body_temperature0.54506373
126MP0002089_abnormal_postnatal_growth/wei0.53246102
127MP0005248_abnormal_Harderian_gland0.52022513

Predicted human phenotypes

RankGene SetZ-score
1Focal motor seizures (HP:0011153)6.42587844
2Myokymia (HP:0002411)6.32742777
3Focal seizures (HP:0007359)5.28452013
4Progressive cerebellar ataxia (HP:0002073)4.60377806
5Visual hallucinations (HP:0002367)4.58958292
6Epileptic encephalopathy (HP:0200134)4.53847387
7Action tremor (HP:0002345)4.12506479
8Febrile seizures (HP:0002373)3.99259971
9Atonic seizures (HP:0010819)3.74187060
10True hermaphroditism (HP:0010459)3.72744403
11Pancreatic fibrosis (HP:0100732)3.63766768
12Molar tooth sign on MRI (HP:0002419)3.61878700
13Abnormality of midbrain morphology (HP:0002418)3.61878700
14Supranuclear gaze palsy (HP:0000605)3.61648686
15Pancreatic cysts (HP:0001737)3.59498286
16Nephronophthisis (HP:0000090)3.53502633
17Absence seizures (HP:0002121)3.51999908
18Ankle clonus (HP:0011448)3.46138770
19Broad-based gait (HP:0002136)3.40041378
20Genetic anticipation (HP:0003743)3.35471410
21Generalized tonic-clonic seizures (HP:0002069)3.28965394
22Gaze-evoked nystagmus (HP:0000640)3.24353672
23Poor eye contact (HP:0000817)3.20033232
24Dialeptic seizures (HP:0011146)3.19204419
25Mutism (HP:0002300)3.12118135
26Impaired vibration sensation in the lower limbs (HP:0002166)3.10599472
27Urinary bladder sphincter dysfunction (HP:0002839)3.09741748
28Absent/shortened dynein arms (HP:0200106)3.02354721
29Dynein arm defect of respiratory motile cilia (HP:0012255)3.02354721
30Abnormality of the renal medulla (HP:0100957)3.00618100
31Gait imbalance (HP:0002141)2.99896528
32Abnormal respiratory motile cilium morphology (HP:0005938)2.97931804
33Abnormal respiratory epithelium morphology (HP:0012253)2.97931804
34Depression (HP:0000716)2.95463090
35Dysdiadochokinesis (HP:0002075)2.93456020
36Abnormal social behavior (HP:0012433)2.91632972
37Impaired social interactions (HP:0000735)2.91632972
38Medial flaring of the eyebrow (HP:0010747)2.91567091
39Truncal ataxia (HP:0002078)2.85424234
40Abnormal ciliary motility (HP:0012262)2.83935148
41Abnormality of the lower motor neuron (HP:0002366)2.82971240
42Chronic hepatic failure (HP:0100626)2.82798551
43Abnormal eating behavior (HP:0100738)2.80710619
44Megalencephaly (HP:0001355)2.79616222
45Postural instability (HP:0002172)2.77110377
46Papilledema (HP:0001085)2.76666724
47Dysmetria (HP:0001310)2.75961230
48Hemiparesis (HP:0001269)2.73102011
49Drooling (HP:0002307)2.72434388
50Excessive salivation (HP:0003781)2.72434388
51Hemiplegia (HP:0002301)2.69038814
52Cystic liver disease (HP:0006706)2.68804933
53Hyperventilation (HP:0002883)2.67525426
54Amblyopia (HP:0000646)2.66824981
55Urinary urgency (HP:0000012)2.65330859
56Impaired smooth pursuit (HP:0007772)2.63287677
57Abnormality of the corticospinal tract (HP:0002492)2.55335557
58Congenital primary aphakia (HP:0007707)2.53082139
59Spastic gait (HP:0002064)2.51847091
60Abnormal respiratory motile cilium physiology (HP:0012261)2.48000746
61Anxiety (HP:0000739)2.47496662
62Intention tremor (HP:0002080)2.46952986
63Lissencephaly (HP:0001339)2.46226236
64Insidious onset (HP:0003587)2.45006158
65Termporal pattern (HP:0011008)2.45006158
66Diplopia (HP:0000651)2.44772819
67Abnormality of binocular vision (HP:0011514)2.44772819
68Scanning speech (HP:0002168)2.42913360
69Torticollis (HP:0000473)2.41804273
70Stereotypic behavior (HP:0000733)2.40665398
71Type II lissencephaly (HP:0007260)2.40260061
72Optic nerve hypoplasia (HP:0000609)2.38320606
73Limb dystonia (HP:0002451)2.38021783
74Pointed chin (HP:0000307)2.37528885
75Abnormality of ocular smooth pursuit (HP:0000617)2.37505649
76Progressive inability to walk (HP:0002505)2.35728715
77Nephrogenic diabetes insipidus (HP:0009806)2.35420843
78Insomnia (HP:0100785)2.33550555
79Fetal akinesia sequence (HP:0001989)2.33515636
80Amyotrophic lateral sclerosis (HP:0007354)2.33512604
81Epileptiform EEG discharges (HP:0011182)2.33506162
82Oligodactyly (hands) (HP:0001180)2.29965361
83Abnormality of the labia minora (HP:0012880)2.29123458
84EEG with generalized epileptiform discharges (HP:0011198)2.29013837
85Anencephaly (HP:0002323)2.28517429
86Genital tract atresia (HP:0001827)2.28068949
87Septo-optic dysplasia (HP:0100842)2.26765916
88Vaginal atresia (HP:0000148)2.25620133
89Focal dystonia (HP:0004373)2.25489214
90Respiratory insufficiency due to defective ciliary clearance (HP:0200073)2.23478873
91Congenital stationary night blindness (HP:0007642)2.23235536
92Dysmetric saccades (HP:0000641)2.21973939
93Hypsarrhythmia (HP:0002521)2.21851171
94Lower limb muscle weakness (HP:0007340)2.20881498
95Neurofibrillary tangles (HP:0002185)2.20085055
96Absent speech (HP:0001344)2.17785020
97Pachygyria (HP:0001302)2.16374037
98Agitation (HP:0000713)2.15899571
99Bradykinesia (HP:0002067)2.15217314
100Annular pancreas (HP:0001734)2.14149226
101Postaxial hand polydactyly (HP:0001162)2.13280215
102Retinal dysplasia (HP:0007973)2.13133611
103Postaxial foot polydactyly (HP:0001830)2.12502307
104Polyphagia (HP:0002591)2.12401652
105Obstructive sleep apnea (HP:0002870)2.10872125
106Cerebral inclusion bodies (HP:0100314)2.10773933
107Sclerocornea (HP:0000647)2.10511898
108Aqueductal stenosis (HP:0002410)2.08249858
109Tubular atrophy (HP:0000092)2.05029781
110Inappropriate behavior (HP:0000719)2.02004321
111Aplasia/Hypoplasia of the optic nerve (HP:0008058)2.01773593
112Pheochromocytoma (HP:0002666)2.01358997
113Impaired vibratory sensation (HP:0002495)2.01045303
114Aplasia/Hypoplasia of the tongue (HP:0010295)2.00320620
115Abnormality of the renal cortex (HP:0011035)1.99255280
116Protruding tongue (HP:0010808)1.98955459
117Poor coordination (HP:0002370)1.97853859
118Ventricular fibrillation (HP:0001663)1.97722084
119Abnormal drinking behavior (HP:0030082)1.94749496
120Polydipsia (HP:0001959)1.94749496
121Anophthalmia (HP:0000528)1.94037544
122Congenital hepatic fibrosis (HP:0002612)1.92770579
123Rib fusion (HP:0000902)1.90971359
124Craniofacial dystonia (HP:0012179)1.90614742
125Status epilepticus (HP:0002133)1.88577975
126Rhinitis (HP:0012384)1.88138237
127Intestinal atresia (HP:0011100)1.87594029
128Narrow forehead (HP:0000341)1.85535044
129Apathy (HP:0000741)1.85480047
130Occipital encephalocele (HP:0002085)1.82856148
131Inability to walk (HP:0002540)1.81144196
132Hepatoblastoma (HP:0002884)1.80224084
133Clonus (HP:0002169)1.79860033
134Akinesia (HP:0002304)1.79089292
135Macroorchidism (HP:0000053)1.78997030
136Incomplete penetrance (HP:0003829)1.78933422
137Abnormality of salivation (HP:0100755)1.78714170
138Preaxial hand polydactyly (HP:0001177)1.78375884
139Aplasia/Hypoplasia of the brainstem (HP:0007362)1.77923701
140Hypoplasia of the brainstem (HP:0002365)1.77923701
141Specific learning disability (HP:0001328)1.77415690
142Oligodactyly (HP:0012165)1.75307721
143Elfin facies (HP:0004428)1.74551450
144Lower limb amyotrophy (HP:0007210)1.74440453
145Morphological abnormality of the pyramidal tract (HP:0002062)1.72735552
146Gait ataxia (HP:0002066)1.72564548
147Aplasia involving bones of the extremities (HP:0009825)1.71932928
148Aplasia involving bones of the upper limbs (HP:0009823)1.71932928
149Aplasia of the phalanges of the hand (HP:0009802)1.71932928
150Cutaneous finger syndactyly (HP:0010554)1.71675051
151Hyperacusis (HP:0010780)1.71586684
152Short 4th metacarpal (HP:0010044)1.71489066
153Aplasia/Hypoplasia of the 4th metacarpal (HP:0010042)1.71489066
154Lower limb asymmetry (HP:0100559)1.70637750
155Abnormality of the diencephalon (HP:0010662)1.69135962
156Intellectual disability, profound (HP:0002187)1.68975038
157Abnormality of saccadic eye movements (HP:0000570)1.68494917
158Patellar aplasia (HP:0006443)1.65962972
159Male pseudohermaphroditism (HP:0000037)1.65315094
160Tented upper lip vermilion (HP:0010804)1.64722053
161Pendular nystagmus (HP:0012043)1.64439823
162Esophageal atresia (HP:0002032)1.61994054
163Tubulointerstitial nephritis (HP:0001970)1.61907139
164Gastrointestinal atresia (HP:0002589)1.60855112

Predicted kinase interactions (KEA)

RankGene SetZ-score
1MARK14.45317611
2NTRK34.13469272
3MAP3K93.71555860
4EPHA43.43239287
5MAP3K42.89642770
6MINK12.79795878
7DAPK22.53313590
8PAK62.42380035
9NTRK22.37134479
10MAPK152.29706446
11MAP2K72.29600077
12PRKD31.98357282
13FRK1.95168235
14CAMKK11.94657370
15KSR11.79965526
16BMPR1B1.75712295
17MAP2K41.75028415
18KSR21.71709902
19SIK21.65193804
20MAPK131.64550481
21MAP4K21.62214698
22CDK51.60546320
23NTRK11.59254290
24ADRBK21.55113263
25TNIK1.55029245
26CASK1.52444222
27WNK41.48357864
28MAP3K121.45625747
29PRPF4B1.43682231
30STK381.40600484
31BCR1.38313697
32DAPK11.35644678
33PHKG11.32080952
34PHKG21.32080952
35PNCK1.31220259
36TYRO31.29233315
37UHMK11.19926421
38LATS21.19844081
39PRKCG1.19397772
40PLK21.16596739
41CDK191.15736969
42GRK51.10275240
43SGK2231.07633274
44SGK4941.07633274
45RIPK41.03889640
46CAMKK21.02076199
47INSRR1.01153035
48PKN11.00192911
49CDK180.98248869
50STK390.98156162
51CDK150.96640261
52MAP3K20.95938784
53TAOK10.95739904
54GRK10.95120869
55SGK20.94913602
56STK110.94641717
57MKNK20.94565996
58CAMK10.93171293
59CDK140.91370890
60RET0.90401184
61CAMK1G0.90359972
62MARK20.89936152
63FES0.89043721
64CSNK1G20.86066657
65ALK0.85205410
66CAMK2A0.84742951
67CDK11A0.84095722
68SGK30.83935632
69PRKCH0.83878816
70LMTK20.83491887
71ERBB30.83243021
72ACVR1B0.81457793
73PAK30.81017525
74RIPK10.78019792
75NUAK10.75104963
76DYRK1A0.74415726
77ZAK0.70758660
78SGK10.69357313
79CSNK1G30.69189049
80EPHA30.68631708
81TRIM280.67825578
82STK38L0.65926850
83NEK60.65812436
84CAMK1D0.65397969
85SIK30.64722093
86CSNK1G10.64663695
87CAMK2B0.63198390
88CDC42BPA0.62164895
89CCNB10.60330518
90DDR20.58936553
91PRKCZ0.58608297
92WNK10.55800349
93PINK10.54787235
94ADRBK10.54295024
95RPS6KA20.53641681
96CAMK40.53184687
97RPS6KA30.52660208
98WEE10.51948156
99OXSR10.51074451
100FYN0.50870114
101MAP3K130.50347713
102CDK30.49638150
103PTK2B0.49209007
104PDK10.48882401
105MKNK10.48084567
106EPHB20.48027555
107PRKACA0.48026012
108DYRK20.47625178
109FGFR20.47075618
110MAP3K70.46740403
111ARAF0.45058234
112TAOK30.43912392
113DMPK0.43359091
114MAPK100.43147873
115DYRK1B0.43114977
116FER0.42998651
117TNK20.42580409
118TLK10.42289099
119RAF10.42197680
120PRKCE0.41831203
121ICK0.41406814
122NEK10.41386668
123PDPK10.41298370
124WNK30.41212438
125CSNK1A10.41185679
126CSNK1D0.41032343
127DYRK30.40860812
128ROCK20.40345494
129PRKG10.39190098
130ROCK10.38944324
131ERBB20.37470186
132TGFBR10.36696655
133MAP3K60.36059946
134CSNK1A1L0.35904685
135VRK10.35836920
136CSNK1E0.34213637
137PRKAA10.33933316
138PIK3CA0.31804934

Predicted pathways (KEGG)

RankGene SetZ-score
1Nicotine addiction_Homo sapiens_hsa050333.57970166
2Synaptic vesicle cycle_Homo sapiens_hsa047213.11147742
3GABAergic synapse_Homo sapiens_hsa047272.64394999
4Circadian entrainment_Homo sapiens_hsa047132.64385904
5Glutamatergic synapse_Homo sapiens_hsa047242.58535861
6Retrograde endocannabinoid signaling_Homo sapiens_hsa047232.53022748
7Olfactory transduction_Homo sapiens_hsa047402.50022330
8Long-term potentiation_Homo sapiens_hsa047202.49164672
9Morphine addiction_Homo sapiens_hsa050322.35551931
10Amphetamine addiction_Homo sapiens_hsa050312.19707246
11Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049612.18848995
12Dopaminergic synapse_Homo sapiens_hsa047282.06934761
13Salivary secretion_Homo sapiens_hsa049702.05033867
14Synthesis and degradation of ketone bodies_Homo sapiens_hsa000722.02899061
15Insulin secretion_Homo sapiens_hsa049111.89571041
16Cholinergic synapse_Homo sapiens_hsa047251.89232914
17Gastric acid secretion_Homo sapiens_hsa049711.83926739
18Aldosterone synthesis and secretion_Homo sapiens_hsa049251.77708054
19Long-term depression_Homo sapiens_hsa047301.69795110
20Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042611.64456378
21Butanoate metabolism_Homo sapiens_hsa006501.63779659
22Taste transduction_Homo sapiens_hsa047421.60388405
23Oxytocin signaling pathway_Homo sapiens_hsa049211.59747750
24Cocaine addiction_Homo sapiens_hsa050301.56141058
25Renin secretion_Homo sapiens_hsa049241.49672837
26Serotonergic synapse_Homo sapiens_hsa047261.48336214
27Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049601.48033522
28Vasopressin-regulated water reabsorption_Homo sapiens_hsa049621.46880021
29Linoleic acid metabolism_Homo sapiens_hsa005911.46151850
30GnRH signaling pathway_Homo sapiens_hsa049121.43749648
31Calcium signaling pathway_Homo sapiens_hsa040201.43195688
32* Axon guidance_Homo sapiens_hsa043601.41454843
33Gap junction_Homo sapiens_hsa045401.38712373
34Basal cell carcinoma_Homo sapiens_hsa052171.38433123
35alpha-Linolenic acid metabolism_Homo sapiens_hsa005921.34881345
36Type II diabetes mellitus_Homo sapiens_hsa049301.30032842
37Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047501.26297138
38Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006011.25655169
39cAMP signaling pathway_Homo sapiens_hsa040241.24873648
40Glioma_Homo sapiens_hsa052141.23990430
41Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049641.21227117
42Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005341.19093055
43Estrogen signaling pathway_Homo sapiens_hsa049151.18574120
44ErbB signaling pathway_Homo sapiens_hsa040121.18400682
45Phosphatidylinositol signaling system_Homo sapiens_hsa040701.18082930
46Oxidative phosphorylation_Homo sapiens_hsa001901.13631089
47Ether lipid metabolism_Homo sapiens_hsa005651.11717805
48Nitrogen metabolism_Homo sapiens_hsa009101.08484313
49Melanogenesis_Homo sapiens_hsa049161.08283278
50Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005631.04136958
51cGMP-PKG signaling pathway_Homo sapiens_hsa040220.98732905
52Steroid biosynthesis_Homo sapiens_hsa001000.98658160
53Dorso-ventral axis formation_Homo sapiens_hsa043200.94788605
54Collecting duct acid secretion_Homo sapiens_hsa049660.94185261
55Phospholipase D signaling pathway_Homo sapiens_hsa040720.93219788
56Parkinsons disease_Homo sapiens_hsa050120.91299379
57Phototransduction_Homo sapiens_hsa047440.90050193
58Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.88816466
59Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.86866312
60Oocyte meiosis_Homo sapiens_hsa041140.83714553
61Endometrial cancer_Homo sapiens_hsa052130.82727595
62Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001300.82188617
63Neurotrophin signaling pathway_Homo sapiens_hsa047220.81068325
64Choline metabolism in cancer_Homo sapiens_hsa052310.80877230
65Vascular smooth muscle contraction_Homo sapiens_hsa042700.80221396
66Huntingtons disease_Homo sapiens_hsa050160.79453626
67Pancreatic secretion_Homo sapiens_hsa049720.78965208
68Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.78726583
69MAPK signaling pathway_Homo sapiens_hsa040100.78181816
70Carbohydrate digestion and absorption_Homo sapiens_hsa049730.75495598
71Maturity onset diabetes of the young_Homo sapiens_hsa049500.75470807
72ABC transporters_Homo sapiens_hsa020100.74658169
73Alzheimers disease_Homo sapiens_hsa050100.74368964
74Dilated cardiomyopathy_Homo sapiens_hsa054140.74151567
75Thyroid hormone signaling pathway_Homo sapiens_hsa049190.74054921
76Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.73432066
77Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.72675269
78Thyroid hormone synthesis_Homo sapiens_hsa049180.72238215
79Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.70477723
80mTOR signaling pathway_Homo sapiens_hsa041500.69785018
81Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.69697844
82VEGF signaling pathway_Homo sapiens_hsa043700.69227687
83Cardiac muscle contraction_Homo sapiens_hsa042600.65955412
84Rap1 signaling pathway_Homo sapiens_hsa040150.65249790
85Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.64321807
86Wnt signaling pathway_Homo sapiens_hsa043100.63894543
87Ras signaling pathway_Homo sapiens_hsa040140.63596533
88Propanoate metabolism_Homo sapiens_hsa006400.63310526
89beta-Alanine metabolism_Homo sapiens_hsa004100.63113602
90Tryptophan metabolism_Homo sapiens_hsa003800.62711091
91Renal cell carcinoma_Homo sapiens_hsa052110.61667038
92Colorectal cancer_Homo sapiens_hsa052100.60479493
93Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.60310513
94Vibrio cholerae infection_Homo sapiens_hsa051100.59800388
95Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.59411069
96Sphingolipid signaling pathway_Homo sapiens_hsa040710.58418375
97Primary bile acid biosynthesis_Homo sapiens_hsa001200.57204265
98Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054120.56588396
99Endocytosis_Homo sapiens_hsa041440.56204053
100Selenocompound metabolism_Homo sapiens_hsa004500.55981997
101Regulation of autophagy_Homo sapiens_hsa041400.55703271
102Basal transcription factors_Homo sapiens_hsa030220.55265569
103Non-small cell lung cancer_Homo sapiens_hsa052230.54897430
104Circadian rhythm_Homo sapiens_hsa047100.53905364
105Inositol phosphate metabolism_Homo sapiens_hsa005620.52080084
106Longevity regulating pathway - mammal_Homo sapiens_hsa042110.50773871
107Caffeine metabolism_Homo sapiens_hsa002320.50254037
108Peroxisome_Homo sapiens_hsa041460.48595847
109Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.48594685
110Alcoholism_Homo sapiens_hsa050340.47943382
111Glucagon signaling pathway_Homo sapiens_hsa049220.47781036
112Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.47561634
113Protein export_Homo sapiens_hsa030600.47121640
114Fanconi anemia pathway_Homo sapiens_hsa034600.47005495
115Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.45828958
116Bile secretion_Homo sapiens_hsa049760.45469235
117Insulin signaling pathway_Homo sapiens_hsa049100.44753811
118Fc epsilon RI signaling pathway_Homo sapiens_hsa046640.44229682
119Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.44115610
120Histidine metabolism_Homo sapiens_hsa003400.43809266
121Ascorbate and aldarate metabolism_Homo sapiens_hsa000530.43407386
122Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046660.43100048
123Steroid hormone biosynthesis_Homo sapiens_hsa001400.41286008
124Glycerolipid metabolism_Homo sapiens_hsa005610.40289953
125Taurine and hypotaurine metabolism_Homo sapiens_hsa004300.40199267
126Tight junction_Homo sapiens_hsa045300.39239968
127Chemokine signaling pathway_Homo sapiens_hsa040620.38946032
128Chemical carcinogenesis_Homo sapiens_hsa052040.38618574
129Ovarian steroidogenesis_Homo sapiens_hsa049130.37964775
130Hippo signaling pathway_Homo sapiens_hsa043900.37528998
131Prolactin signaling pathway_Homo sapiens_hsa049170.35996934
132Hedgehog signaling pathway_Homo sapiens_hsa043400.35843546
133Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054100.35322400
134Type I diabetes mellitus_Homo sapiens_hsa049400.34663113
135Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.34569567
136Regulation of actin cytoskeleton_Homo sapiens_hsa048100.32289081

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