SPATA17

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1sperm motility (GO:0030317)9.84852282
2fusion of sperm to egg plasma membrane (GO:0007342)8.98237870
3GTP biosynthetic process (GO:0006183)8.39228652
4regulation of cilium movement (GO:0003352)8.24215303
5ventricular system development (GO:0021591)8.13478114
6sperm-egg recognition (GO:0035036)7.59865493
7acrosome assembly (GO:0001675)7.55249196
8acrosome reaction (GO:0007340)7.54777077
9UTP biosynthetic process (GO:0006228)7.49025096
10multicellular organism reproduction (GO:0032504)7.27780717
11binding of sperm to zona pellucida (GO:0007339)7.14212016
12nucleoside diphosphate phosphorylation (GO:0006165)7.09991276
13spermatid development (GO:0007286)7.06087972
14UTP metabolic process (GO:0046051)7.04826295
15cell wall macromolecule metabolic process (GO:0044036)6.87147518
16cell wall macromolecule catabolic process (GO:0016998)6.87147518
17plasma membrane fusion (GO:0045026)6.74974699
18cell-cell recognition (GO:0009988)6.71145155
19piRNA metabolic process (GO:0034587)6.63111426
20male meiosis (GO:0007140)6.08211105
21reproduction (GO:0000003)6.00348131
22microtubule severing (GO:0051013)5.98580918
23negative regulation of inclusion body assembly (GO:0090084)5.98368827
24intraciliary transport (GO:0042073)5.83415882
25guanosine-containing compound biosynthetic process (GO:1901070)5.72850626
26synaptonemal complex organization (GO:0070193)5.68050895
27single fertilization (GO:0007338)5.66144921
28CTP biosynthetic process (GO:0006241)5.59528725
29CTP metabolic process (GO:0046036)5.59528725
30behavioral response to nicotine (GO:0035095)5.46402413
31left/right axis specification (GO:0070986)5.39521960
32pyrimidine ribonucleoside triphosphate biosynthetic process (GO:0009209)5.12026112
33cilium organization (GO:0044782)5.07176353
34microtubule bundle formation (GO:0001578)5.00245464
35cilium morphogenesis (GO:0060271)4.96682321
36fertilization (GO:0009566)4.95790950
37pyrimidine ribonucleoside triphosphate metabolic process (GO:0009208)4.93689449
38spermatogenesis (GO:0007283)4.88344597
39regulation of microtubule-based movement (GO:0060632)4.87265190
40male meiosis I (GO:0007141)4.87064377
41male gamete generation (GO:0048232)4.86283835
42cilium assembly (GO:0042384)4.79842196
43sperm capacitation (GO:0048240)4.74709240
44regulation of inclusion body assembly (GO:0090083)4.73620348
45synaptonemal complex assembly (GO:0007130)4.61714175
46gamete generation (GO:0007276)4.51006526
47protein localization to cilium (GO:0061512)4.46453577
48cellular component assembly involved in morphogenesis (GO:0010927)4.38129509
49pyrimidine nucleoside triphosphate biosynthetic process (GO:0009148)4.32358805
50microtubule-based movement (GO:0007018)4.29112496
51meiotic cell cycle (GO:0051321)4.12191317
52DNA methylation involved in gamete generation (GO:0043046)4.08455852
53protein polyglutamylation (GO:0018095)4.06736553
54organic cation transport (GO:0015695)4.06223205
55pyrimidine nucleoside triphosphate metabolic process (GO:0009147)3.95585871
56centriole assembly (GO:0098534)3.92284394
57germ cell development (GO:0007281)3.87991612
58meiosis I (GO:0007127)3.81405465
59nucleotide phosphorylation (GO:0046939)3.75300853
60cellular process involved in reproduction in multicellular organism (GO:0022412)3.74400912
61nucleoside diphosphate metabolic process (GO:0009132)3.67240023
62spermatid nucleus differentiation (GO:0007289)3.63318321
63multicellular organismal reproductive process (GO:0048609)3.58834866
64left/right pattern formation (GO:0060972)3.58415502
65response to pheromone (GO:0019236)3.58044782
66indolalkylamine metabolic process (GO:0006586)3.52885874
67water-soluble vitamin biosynthetic process (GO:0042364)3.48372665
68calcium ion-dependent exocytosis (GO:0017156)3.46736867
69cell projection assembly (GO:0030031)3.44605104
70cell proliferation in forebrain (GO:0021846)3.44403659
71meiotic nuclear division (GO:0007126)3.35339800
72indole-containing compound catabolic process (GO:0042436)3.33964729
73indolalkylamine catabolic process (GO:0046218)3.33964729
74tryptophan catabolic process (GO:0006569)3.33964729
75cell recognition (GO:0008037)3.32457813
76pyrimidine ribonucleoside biosynthetic process (GO:0046132)3.29786184
77centriole replication (GO:0007099)3.26955389
78sulfation (GO:0051923)3.22982393
79DNA deamination (GO:0045006)3.20351120
80seminiferous tubule development (GO:0072520)3.18313566
81protein refolding (GO:0042026)3.14494677
82chaperone-mediated protein complex assembly (GO:0051131)3.13396741
83pyrimidine ribonucleotide biosynthetic process (GO:0009220)3.12954152
84chromosome organization involved in meiosis (GO:0070192)3.12753326
85kynurenine metabolic process (GO:0070189)3.11868388
86microtubule depolymerization (GO:0007019)3.08667358
87transmission of nerve impulse (GO:0019226)3.07893253
88somite development (GO:0061053)3.03844157
89glycerol ether metabolic process (GO:0006662)3.01983771
90protein complex biogenesis (GO:0070271)3.00628440
91nonmotile primary cilium assembly (GO:0035058)3.00014298
92L-fucose catabolic process (GO:0042355)2.99163079
93fucose catabolic process (GO:0019317)2.99163079
94L-fucose metabolic process (GO:0042354)2.99163079
95pyrimidine ribonucleotide metabolic process (GO:0009218)2.96827573
96photoreceptor cell maintenance (GO:0045494)2.96200930
97detection of light stimulus involved in visual perception (GO:0050908)2.95134170
98detection of light stimulus involved in sensory perception (GO:0050962)2.95134170
99detection of mechanical stimulus involved in sensory perception of sound (GO:0050910)2.94426274
100otic vesicle formation (GO:0030916)2.93005362
101serotonin metabolic process (GO:0042428)2.92676282
102primary amino compound metabolic process (GO:1901160)2.91980340
103purine ribonucleoside triphosphate biosynthetic process (GO:0009206)2.90979458
104regulation of collateral sprouting (GO:0048670)2.90913408
105cornea development in camera-type eye (GO:0061303)2.88941555
106indole-containing compound metabolic process (GO:0042430)2.88663103
107ether metabolic process (GO:0018904)2.86455728
108purine nucleoside triphosphate biosynthetic process (GO:0009145)2.83256467
109regulation of meiosis I (GO:0060631)2.82730495
110gamma-aminobutyric acid transport (GO:0015812)2.80365384
111mitochondrial respiratory chain complex I assembly (GO:0032981)2.77778146
112NADH dehydrogenase complex assembly (GO:0010257)2.77778146
113mitochondrial respiratory chain complex I biogenesis (GO:0097031)2.77778146
114neuronal action potential (GO:0019228)2.75350776
115glycolytic process (GO:0006096)2.74702243
116regulation of action potential (GO:0098900)2.73320945
117tryptophan metabolic process (GO:0006568)2.71798107
118negative regulation of transcription regulatory region DNA binding (GO:2000678)2.71154007
119smoothened signaling pathway (GO:0007224)2.70837403
120membrane depolarization during cardiac muscle cell action potential (GO:0086012)2.70342735
121regulation of glucose import in response to insulin stimulus (GO:2001273)2.68766586
122determination of left/right symmetry (GO:0007368)2.67727086
123negative regulation of appetite (GO:0032099)2.66646410
124negative regulation of response to food (GO:0032096)2.66646410
125cellular ketone body metabolic process (GO:0046950)2.66476254
126mitochondrial respiratory chain complex assembly (GO:0033108)2.66012332
127one-carbon compound transport (GO:0019755)2.65898859
128retinal cone cell development (GO:0046549)2.63549059
129pyrimidine ribonucleoside metabolic process (GO:0046131)2.62502634
130photoreceptor cell development (GO:0042461)2.62035499
131limb development (GO:0060173)2.61528073
132appendage development (GO:0048736)2.61528073
133neural tube formation (GO:0001841)2.61300341
134regulation of mesoderm development (GO:2000380)2.58500604
135determination of bilateral symmetry (GO:0009855)2.58072432
136spinal cord motor neuron differentiation (GO:0021522)2.57373462
137pharyngeal system development (GO:0060037)2.57112687
138cellular biogenic amine catabolic process (GO:0042402)2.56477372
139amine catabolic process (GO:0009310)2.56477372
140negative regulation of systemic arterial blood pressure (GO:0003085)2.55997971
141nucleoside triphosphate biosynthetic process (GO:0009142)2.54029130
142regulation of posttranscriptional gene silencing (GO:0060147)2.53457434
143regulation of gene silencing by miRNA (GO:0060964)2.53457434
144regulation of gene silencing by RNA (GO:0060966)2.53457434
145oxygen transport (GO:0015671)2.53054503
146specification of symmetry (GO:0009799)2.52189902
147behavioral response to ethanol (GO:0048149)2.52154613
148multicellular organismal development (GO:0007275)2.52062624
149synaptic transmission, cholinergic (GO:0007271)2.51579866
150parturition (GO:0007567)2.51416002
151drug catabolic process (GO:0042737)2.51190466
152regulation of macrophage chemotaxis (GO:0010758)2.51010644
153adaptation of signaling pathway (GO:0023058)2.47739729
154kidney morphogenesis (GO:0060993)2.46806765
155platelet dense granule organization (GO:0060155)2.45823549
156regulation of neurotransmitter uptake (GO:0051580)2.44545574
157reflex (GO:0060004)2.43778531
158positive regulation of oligodendrocyte differentiation (GO:0048714)2.43568854
159ketone body metabolic process (GO:1902224)2.42614291
160forebrain morphogenesis (GO:0048853)2.42038682
161negative regulation of T cell differentiation in thymus (GO:0033085)2.41984548
162eye photoreceptor cell development (GO:0042462)2.40173381
163preassembly of GPI anchor in ER membrane (GO:0016254)2.39895700
164lateral sprouting from an epithelium (GO:0060601)2.38062920
165axonemal dynein complex assembly (GO:0070286)14.9693694
166cilium or flagellum-dependent cell motility (GO:0001539)14.6555168
167cilium movement (GO:0003341)14.2749177
168epithelial cilium movement (GO:0003351)12.6545836
169axoneme assembly (GO:0035082)10.9412847
170epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287)10.2109200
171motile cilium assembly (GO:0044458)10.1420308

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse5.81249141
2EZH2_22144423_ChIP-Seq_EOC_Human4.10007079
3TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse3.82417544
4CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human3.15491135
5BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse3.10551646
6PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse2.97555146
7RBPJ_22232070_ChIP-Seq_NCS_Mouse2.95883893
8GBX2_23144817_ChIP-Seq_PC3_Human2.89809739
9IGF1R_20145208_ChIP-Seq_DFB_Human2.46432748
10FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse2.42367547
11GATA1_26923725_Chip-Seq_HPCs_Mouse2.31392991
12GLI1_17442700_ChIP-ChIP_MESCs_Mouse2.28679043
13HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse2.20756681
14FLI1_27457419_Chip-Seq_LIVER_Mouse2.17787182
15POU3F2_20337985_ChIP-ChIP_501MEL_Human2.09236251
16GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse2.08699452
17PCGF2_27294783_Chip-Seq_ESCs_Mouse2.03872565
18VDR_22108803_ChIP-Seq_LS180_Human1.99108611
19* EWS_26573619_Chip-Seq_HEK293_Human1.86461316
20PCGF2_27294783_Chip-Seq_NPCs_Mouse1.85382406
21CEBPD_23245923_ChIP-Seq_MEFs_Mouse1.82004740
22CTBP2_25329375_ChIP-Seq_LNCAP_Human1.79080137
23EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human1.78774378
24NR4A2_19515692_ChIP-ChIP_MN9D_Mouse1.78547450
25KLF4_25985364_ChIP-Seq_ATHEROSCLEROSIS_LESION_Mouse1.75290936
26RNF2_27304074_Chip-Seq_NSC_Mouse1.70767630
27* SUZ12_27294783_Chip-Seq_NPCs_Mouse1.67517259
28STAT6_21828071_ChIP-Seq_BEAS2B_Human1.64787397
29PIAS1_25552417_ChIP-Seq_VCAP_Human1.64417249
30POU5F1_26923725_Chip-Seq_MESODERM_Mouse1.64158569
31TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.64158569
32AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human1.63667095
33PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.61494760
34CBX2_27304074_Chip-Seq_ESCs_Mouse1.60625794
35MEIS1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse1.59504180
36* NFE2_27457419_Chip-Seq_LIVER_Mouse1.58543502
37* TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse1.56985521
38UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human1.54954550
39* STAT3_23295773_ChIP-Seq_U87_Human1.51009499
40TAL1_21186366_ChIP-Seq_BM-HSCs_Mouse1.49685135
41WDR5_24793694_ChIP-Seq_LNCAP_Human1.45097329
42EED_16625203_ChIP-ChIP_MESCs_Mouse1.44059520
43AR_25329375_ChIP-Seq_VCAP_Human1.43779846
44TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.43764169
45BCAT_22108803_ChIP-Seq_LS180_Human1.43149691
46SALL1_21062744_ChIP-ChIP_HESCs_Human1.42549330
47IRF1_19129219_ChIP-ChIP_H3396_Human1.41942419
48TAL1_26923725_Chip-Seq_HPCs_Mouse1.41112026
49SIN3B_21632747_ChIP-Seq_MESCs_Mouse1.39400728
50MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human1.39394876
51KAP1_22055183_ChIP-Seq_ESCs_Mouse1.38396296
52* SMAD4_21799915_ChIP-Seq_A2780_Human1.37918609
53REST_21632747_ChIP-Seq_MESCs_Mouse1.37519629
54ZFP322A_24550733_ChIP-Seq_MESCs_Mouse1.37459569
55JARID2_20064375_ChIP-Seq_MESCs_Mouse1.37036819
56ELK4_26923725_Chip-Seq_MESODERM_Mouse1.35622114
57RCOR1_19997604_ChIP-ChIP_NEURONS_Mouse1.34929418
58* SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.34896366
59* ZFP57_27257070_Chip-Seq_ESCs_Mouse1.34767419
60STAT1_17558387_ChIP-Seq_HELA_Human1.34466949
61HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human1.34458438
62IRF4_20064451_ChIP-Seq_CD4+T_Mouse1.33352007
63CBP_20019798_ChIP-Seq_JUKART_Human1.33352007
64EZH2_27304074_Chip-Seq_ESCs_Mouse1.33168429
65* NANOG_18555785_Chip-Seq_ESCs_Mouse1.32298126
66CTBP1_25329375_ChIP-Seq_LNCAP_Human1.32124745
67TAF15_26573619_Chip-Seq_HEK293_Human1.29107772
68* EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse1.28812670
69NANOG_19829295_ChIP-Seq_ESCs_Human1.28352365
70SOX2_19829295_ChIP-Seq_ESCs_Human1.28352365
71SUZ12_18692474_ChIP-Seq_MESCs_Mouse1.26827826
72* RUNX2_22187159_ChIP-Seq_PCA_Human1.26172864
73SOX2_22085726_ChIP-Seq_NPCs_Mouse1.26005281
74PBX_27287812_Chip-Seq_EMBYONIC-LIMB_Mouse1.24762255
75MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.24761456
76FUS_26573619_Chip-Seq_HEK293_Human1.24663735
77SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.24053068
78KLF5_20875108_ChIP-Seq_MESCs_Mouse1.23760933
79KDM2B_26808549_Chip-Seq_REH_Human1.23057067
80TP53_22573176_ChIP-Seq_HFKS_Human1.22082128
81* CRX_20693478_ChIP-Seq_RETINA_Mouse1.21711154
82TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human1.20894034
83ERG_20517297_ChIP-Seq_VCAP_Human1.20192181
84* FOXA1_25329375_ChIP-Seq_VCAP_Human1.20076852
85* FOXA1_27270436_Chip-Seq_PROSTATE_Human1.20076852
86PRDM14_20953172_ChIP-Seq_ESCs_Human1.19687434
87* P53_22387025_ChIP-Seq_ESCs_Mouse1.19051893
88AR_21572438_ChIP-Seq_LNCaP_Human1.17099317
89GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse1.17071772
90SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.16733565
91* OCT4_18555785_Chip-Seq_ESCs_Mouse1.16580693
92SUZ12_18555785_ChIP-Seq_MESCs_Mouse1.15534935
93RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.14743188
94SUZ12_16625203_ChIP-ChIP_MESCs_Mouse1.14551417
95JARID2_20075857_ChIP-Seq_MESCs_Mouse1.14520824
96NCOR_22424771_ChIP-Seq_293T_Human1.13953323
97MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse1.13760658
98FLI1_21867929_ChIP-Seq_TH2_Mouse1.13563562
99ZNF274_21170338_ChIP-Seq_K562_Hela1.12551646
100* CDX2_21402776_ChIP-Seq_INTESTINAL-VILLUS_Mouse1.11854147
101* EZH2_27294783_Chip-Seq_NPCs_Mouse1.11540479
102AUTS2_25519132_ChIP-Seq_293T-REX_Human1.11204684
103* EBF1_22473956_ChIP-Seq_LYMPHODE_Mouse1.11188722
104DROSHA_22980978_ChIP-Seq_HELA_Human1.10808087
105* CMYC_18555785_Chip-Seq_ESCs_Mouse1.10641398
106* STAT3_18555785_Chip-Seq_ESCs_Mouse1.10008930
107ER_23166858_ChIP-Seq_MCF-7_Human1.09884245
108* P300_18555785_Chip-Seq_ESCs_Mouse1.09431881
109OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.08857457
110P300_19829295_ChIP-Seq_ESCs_Human1.08383159
111MYC_18940864_ChIP-ChIP_HL60_Human1.07744214
112* PBX1_22567123_ChIP-ChIP_OVCAR3_Human1.07505576
113FOXA1_21572438_ChIP-Seq_LNCaP_Human1.07141639
114* EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human1.06820227
115* OCT4_21477851_ChIP-Seq_ESCs_Mouse1.06333001
116* SUZ12_18555785_Chip-Seq_ESCs_Mouse1.06321277
117CEBPB_26923725_Chip-Seq_MESODERM_Mouse1.06267557
118* E2F1_18555785_Chip-Seq_ESCs_Mouse1.06212662
119RNF2_16625203_ChIP-ChIP_MESCs_Mouse1.06139874
120* SOX9_26525672_Chip-Seq_Limbbuds_Mouse1.05943871
121* ZFX_18555785_Chip-Seq_ESCs_Mouse1.05846176
122GF1B_26923725_Chip-Seq_HPCs_Mouse1.05747793
123CEBPB_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse1.05197839
124GF1_26923725_Chip-Seq_HPCs_Mouse1.04619024
125P53_22127205_ChIP-Seq_FIBROBLAST_Human1.04305498
126SMAD4_21741376_ChIP-Seq_EPCs_Human1.03382569
127GATA2_21186366_ChIP-Seq_BM-HSCs_Mouse1.03328242
128AR_20517297_ChIP-Seq_VCAP_Human1.02279627
129* SOX2_18555785_Chip-Seq_ESCs_Mouse1.01851221
130* ESRRB_18555785_Chip-Seq_ESCs_Mouse1.01572873
131CEBPB_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.00716159
132ARNT_22903824_ChIP-Seq_MCF-7_Human1.00625479
133RUNX1_27457419_Chip-Seq_LIVER_Mouse1.00549055
134P53_21459846_ChIP-Seq_SAOS-2_Human1.00487223
135SUZ12_27294783_Chip-Seq_ESCs_Mouse1.00406263
136SMAD3_21741376_ChIP-Seq_EPCs_Human0.99462768
137* KLF4_18555785_Chip-Seq_ESCs_Mouse0.98831612
138CTNNB1_24651522_ChIP-Seq_LGR5+_INTESTINAL_STEM_Human0.98502495
139GATA3_21867929_ChIP-Seq_TH1_Mouse0.98452825
140* RAD21_21589869_ChIP-Seq_MESCs_Mouse0.98235082
141SETDB1_19884257_ChIP-Seq_MESCs_Mouse0.97729196
142* TOP2B_26459242_ChIP-Seq_MCF-7_Human0.97480008
143EZH2_27294783_Chip-Seq_ESCs_Mouse0.96610004
144* NR3C1_21868756_ChIP-Seq_MCF10A_Human0.96088813
145* TCF4_23295773_ChIP-Seq_U87_Human0.95918134
146LUZP1_20508642_ChIP-Seq_ESCs_Mouse0.95487069
147* PU1_27457419_Chip-Seq_LIVER_Mouse0.94391419
148LMO2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.93812853
149TCF4_22108803_ChIP-Seq_LS180_Human0.93804767
150BMI1_23680149_ChIP-Seq_NPCS_Mouse0.93782907

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0002653_abnormal_ependyma_morphology5.09281993
2MP0003698_abnormal_male_reproductive4.74295897
3MP0001929_abnormal_gametogenesis4.37267910
4MP0001984_abnormal_olfaction4.07096695
5MP0003136_yellow_coat_color3.27674091
6MP0008877_abnormal_DNA_methylation3.17253779
7MP0002210_abnormal_sex_determination2.91144294
8MP0005670_abnormal_white_adipose2.86799505
9MP0002160_abnormal_reproductive_system2.59159297
10MP0002161_abnormal_fertility/fecundity2.53958292
11MP0002837_dystrophic_cardiac_calcinosis2.47714303
12MP0005623_abnormal_meninges_morphology2.43076136
13MP0002282_abnormal_trachea_morphology2.39287011
14MP0001145_abnormal_male_reproductive2.30015708
15MP0005646_abnormal_pituitary_gland2.19665880
16MP0003195_calcinosis2.14741711
17MP0000653_abnormal_sex_gland2.08971827
18MP0005410_abnormal_fertilization11.3751816
19MP0001968_abnormal_touch/_nociception1.98087751
20MP0004885_abnormal_endolymph1.97273476
21MP0006072_abnormal_retinal_apoptosis1.84679003
22MP0000631_abnormal_neuroendocrine_gland1.79800217
23MP0004145_abnormal_muscle_electrophysio1.78185113
24MP0003880_abnormal_central_pattern1.75912888
25MP0009745_abnormal_behavioral_response1.72575842
26MP0002272_abnormal_nervous_system1.62523698
27MP0006276_abnormal_autonomic_nervous1.59250587
28MP0008872_abnormal_physiological_respon1.57974303
29MP0009046_muscle_twitch1.57890998
30MP0001485_abnormal_pinna_reflex1.55615992
31MP0004142_abnormal_muscle_tone1.55085351
32MP0002928_abnormal_bile_duct1.50711979
33MP0003787_abnormal_imprinting1.46943818
34MP0005389_reproductive_system_phenotype1.46621830
35MP0001440_abnormal_grooming_behavior1.45661920
36MP0000569_abnormal_digit_pigmentation1.42527555
37MP0004133_heterotaxia1.41165168
38MP0005645_abnormal_hypothalamus_physiol1.40539901
39MP0002735_abnormal_chemical_nociception1.35840522
40MP0008004_abnormal_stomach_pH1.33229961
41MP0004043_abnormal_pH_regulation1.32494198
42MP0002277_abnormal_respiratory_mucosa1.30262943
43MP0002822_catalepsy1.29567052
44MP0000372_irregular_coat_pigmentation1.28316569
45MP0001661_extended_life_span1.26762414
46MP0005647_abnormal_sex_gland1.23994966
47MP0003646_muscle_fatigue1.23984780
48MP0008995_early_reproductive_senescence1.21265295
49MP0001986_abnormal_taste_sensitivity1.20905687
50MP0001529_abnormal_vocalization1.19053857
51MP0002163_abnormal_gland_morphology1.17337252
52MP0004742_abnormal_vestibular_system1.17058945
53MP0002064_seizures1.15255178
54MP0001970_abnormal_pain_threshold1.13472578
55MP0003938_abnormal_ear_development1.11470803
56MP0002249_abnormal_larynx_morphology1.11063658
57MP0001501_abnormal_sleep_pattern1.05805825
58MP0005084_abnormal_gallbladder_morpholo1.05054103
59MP0005195_abnormal_posterior_eye1.04789375
60MP0003119_abnormal_digestive_system1.04250204
61MP0000427_abnormal_hair_cycle1.00138422
62MP0000678_abnormal_parathyroid_gland0.99996181
63MP0003122_maternal_imprinting0.99457637
64MP0003011_delayed_dark_adaptation0.97801206
65MP0003635_abnormal_synaptic_transmissio0.97574626
66MP0009384_cardiac_valve_regurgitation0.97558704
67MP0005174_abnormal_tail_pigmentation0.96609387
68MP0003634_abnormal_glial_cell0.96488475
69MP0003121_genomic_imprinting0.95973908
70MP0002733_abnormal_thermal_nociception0.95594493
71MP0001765_abnormal_ion_homeostasis0.94985512
72MP0003878_abnormal_ear_physiology0.93600879
73MP0005377_hearing/vestibular/ear_phenot0.93600879
74MP0003283_abnormal_digestive_organ0.92686026
75MP0002067_abnormal_sensory_capabilities0.91861451
76MP0001905_abnormal_dopamine_level0.91758699
77MP0002184_abnormal_innervation0.91177391
78MP0001919_abnormal_reproductive_system0.91171170
79MP0010386_abnormal_urinary_bladder0.89934062
80MP0008875_abnormal_xenobiotic_pharmacok0.89692520
81MP0000579_abnormal_nail_morphology0.89654549
82MP0002063_abnormal_learning/memory/cond0.87261561
83MP0003690_abnormal_glial_cell0.84651102
84MP0003937_abnormal_limbs/digits/tail_de0.82330504
85MP0005551_abnormal_eye_electrophysiolog0.80161578
86MP0000955_abnormal_spinal_cord0.79148305
87MP0002229_neurodegeneration0.78598485
88MP0000566_synostosis0.77983421
89MP0002102_abnormal_ear_morphology0.77679228
90MP0004924_abnormal_behavior0.77147873
91MP0005386_behavior/neurological_phenoty0.77147873
92MP0000230_abnormal_systemic_arterial0.76972902
93MP0002132_abnormal_respiratory_system0.76746769
94MP0006292_abnormal_olfactory_placode0.76160568
95MP0000383_abnormal_hair_follicle0.73006914
96MP0009250_abnormal_appendicular_skeleto0.72209318
97MP0004019_abnormal_vitamin_homeostasis0.72183714
98MP0005275_abnormal_skin_tensile0.70521138
99MP0002234_abnormal_pharynx_morphology0.70266536
100MP0002133_abnormal_respiratory_system0.70230495
101MP0005388_respiratory_system_phenotype0.70230495
102MP0002938_white_spotting0.68295290
103MP0001270_distended_abdomen0.66181650
104MP0002557_abnormal_social/conspecific_i0.65892406
105MP0000026_abnormal_inner_ear0.65522279
106MP0003718_maternal_effect0.65187569
107MP0000778_abnormal_nervous_system0.64548148
108MP0005394_taste/olfaction_phenotype0.64528815
109MP0005499_abnormal_olfactory_system0.64528815
110MP0009697_abnormal_copulation0.64092982
111MP0005395_other_phenotype0.63354505
112MP0005379_endocrine/exocrine_gland_phen0.62524350
113MP0004272_abnormal_basement_membrane0.62261617
114MP0002736_abnormal_nociception_after0.61521051
115MP0002909_abnormal_adrenal_gland0.61081681
116MP0002734_abnormal_mechanical_nocicepti0.60249421
117MP0001293_anophthalmia0.59976952
118MP0001486_abnormal_startle_reflex0.59435587
119MP0002168_other_aberrant_phenotype0.59419044
120MP0002295_abnormal_pulmonary_circulatio0.58357828
121MP0003633_abnormal_nervous_system0.56730220
122MP0000462_abnormal_digestive_system0.56552429
123MP0002572_abnormal_emotion/affect_behav0.56219292
124MP0005636_abnormal_mineral_homeostasis0.56169092
125MP0002152_abnormal_brain_morphology0.55641498
126MP0004233_abnormal_muscle_weight0.55597155
127MP0002233_abnormal_nose_morphology0.55303870
128MP0005253_abnormal_eye_physiology0.55077998
129MP0003861_abnormal_nervous_system0.53662584
130MP0002638_abnormal_pupillary_reflex0.52717480
131MP0009115_abnormal_fat_cell0.52077510
132MP0000428_abnormal_craniofacial_morphol0.51207666
133MP0001963_abnormal_hearing_physiology0.50689532
134MP0002752_abnormal_somatic_nervous0.50373247
135MP0003329_amyloid_beta_deposits0.47612644
136MP0001177_atelectasis0.47242520
137MP0005391_vision/eye_phenotype0.47145431
138MP0000049_abnormal_middle_ear0.46794763
139MP0008789_abnormal_olfactory_epithelium0.46190496
140MP0001958_emphysema0.45692345
141MP0000534_abnormal_ureter_morphology0.45416502
142MP0002971_abnormal_brown_adipose0.42730968
143MP0003115_abnormal_respiratory_system0.42659768
144MP0002876_abnormal_thyroid_physiology0.41341694
145MP0000751_myopathy0.41324833
146MP0002116_abnormal_craniofacial_bone0.40749197
147MP0001851_eye_inflammation0.40307698
148MP0002109_abnormal_limb_morphology0.40287307
149MP0003279_aneurysm0.38703537

Predicted human phenotypes

RankGene SetZ-score
1Abnormal respiratory motile cilium morphology (HP:0005938)9.84908498
2Abnormal respiratory epithelium morphology (HP:0012253)9.84908498
3Absent/shortened dynein arms (HP:0200106)9.55092228
4Dynein arm defect of respiratory motile cilia (HP:0012255)9.55092228
5Chronic bronchitis (HP:0004469)7.84429621
6Bronchiectasis (HP:0002110)5.83320257
7Nasal polyposis (HP:0100582)5.19124400
8Infertility (HP:0000789)4.65295243
9Abnormality of the nasal mucosa (HP:0000433)4.20907951
10Nephronophthisis (HP:0000090)4.05926105
11Bronchitis (HP:0012387)3.96261566
12Recurrent sinusitis (HP:0011108)3.94032000
13Molar tooth sign on MRI (HP:0002419)3.38298479
14Abnormality of midbrain morphology (HP:0002418)3.38298479
15Pancreatic fibrosis (HP:0100732)3.37982754
16True hermaphroditism (HP:0010459)3.31975056
17Abnormality of the renal medulla (HP:0100957)3.24549051
18Tubulointerstitial nephritis (HP:0001970)3.13883510
19Recurrent otitis media (HP:0000403)3.10310795
20Absent rod-and cone-mediated responses on ERG (HP:0007688)3.08290844
21Congenital stationary night blindness (HP:0007642)3.05114606
22Median cleft lip (HP:0000161)3.03819641
23Tubular atrophy (HP:0000092)2.96930546
24Abnormal rod and cone electroretinograms (HP:0008323)2.86084611
25Medial flaring of the eyebrow (HP:0010747)2.72078376
26Abolished electroretinogram (ERG) (HP:0000550)2.59443812
27Pancreatic cysts (HP:0001737)2.59423748
28Bile duct proliferation (HP:0001408)2.55686561
29Abnormal biliary tract physiology (HP:0012439)2.55686561
30Pendular nystagmus (HP:0012043)2.55182801
31Decreased central vision (HP:0007663)2.54877280
32Progressive cerebellar ataxia (HP:0002073)2.53180973
33Type II lissencephaly (HP:0007260)2.50339647
34Postaxial foot polydactyly (HP:0001830)2.46052674
35Tubulointerstitial abnormality (HP:0001969)2.45176942
36Attenuation of retinal blood vessels (HP:0007843)2.42528793
37Congenital hepatic fibrosis (HP:0002612)2.40761210
38Cystic liver disease (HP:0006706)2.40642427
39Male infertility (HP:0003251)2.39957744
40Occipital encephalocele (HP:0002085)2.38438781
41Genetic anticipation (HP:0003743)2.38330206
42Aplasia/Hypoplasia of the spleen (HP:0010451)2.37441025
43Increased corneal curvature (HP:0100692)2.37412545
44Keratoconus (HP:0000563)2.37412545
45Chronic sinusitis (HP:0011109)2.36838345
46Chronic hepatic failure (HP:0100626)2.35149260
47Asplenia (HP:0001746)2.31252351
48Bony spicule pigmentary retinopathy (HP:0007737)2.28442319
49Congenital primary aphakia (HP:0007707)2.28065462
50Gait imbalance (HP:0002141)2.25354744
51Abnormality of dentin (HP:0010299)2.23845596
52Abdominal situs inversus (HP:0003363)2.21488700
53Abnormality of abdominal situs (HP:0011620)2.21488700
54Aplasia/Hypoplasia of the tongue (HP:0010295)2.18258117
55Supernumerary spleens (HP:0009799)2.08913301
56Fibular hypoplasia (HP:0003038)2.08842045
57Gaze-evoked nystagmus (HP:0000640)2.08412851
58Congenital sensorineural hearing impairment (HP:0008527)2.05575821
59Abnormality of the dental root (HP:0006486)2.04049417
60Taurodontia (HP:0000679)2.04049417
61Abnormality of permanent molar morphology (HP:0011071)2.04049417
62Aplasia/Hypoplasia of the tibia (HP:0005772)2.01251915
63Respiratory insufficiency due to defective ciliary clearance (HP:0200073)13.5274972
64Abnormal respiratory motile cilium physiology (HP:0012261)11.9540490
65Abnormal ciliary motility (HP:0012262)10.6383112
66Rhinitis (HP:0012384)10.5039773
67Congenital, generalized hypertrichosis (HP:0004540)1.96994727
68Postaxial hand polydactyly (HP:0001162)1.95618058
69Abnormality of the renal cortex (HP:0011035)1.95495160
70Abnormality of the dental pulp (HP:0006479)1.95412982
71Tubulointerstitial fibrosis (HP:0005576)1.95252687
72Stage 5 chronic kidney disease (HP:0003774)1.92819435
73Nephrogenic diabetes insipidus (HP:0009806)1.91662482
74Bifid tongue (HP:0010297)1.90585632
75Facial cleft (HP:0002006)1.89698448
76Abnormality of molar (HP:0011077)1.88649458
77Abnormality of molar morphology (HP:0011070)1.88649458
78Renal cortical cysts (HP:0000803)1.88625874
79Genital tract atresia (HP:0001827)1.87855079
80Polydipsia (HP:0001959)1.87666751
81Abnormal drinking behavior (HP:0030082)1.87666751
82Methylmalonic acidemia (HP:0002912)1.85499246
83Hyperventilation (HP:0002883)1.82636735
84Acute necrotizing encephalopathy (HP:0006965)1.80156527
85Decreased circulating renin level (HP:0003351)1.77383134
86Decreased electroretinogram (ERG) amplitude (HP:0000654)1.77382926
87Stenosis of the external auditory canal (HP:0000402)1.77134806
88Mitochondrial inheritance (HP:0001427)1.76919984
89Vaginal atresia (HP:0000148)1.73514450
90Follicular hyperkeratosis (HP:0007502)1.72223675
91Hyperglycinemia (HP:0002154)1.72033951
92Optic nerve hypoplasia (HP:0000609)1.71691430
93Abnormality of the middle phalanges of the toes (HP:0010183)1.71611609
94Oculomotor apraxia (HP:0000657)1.68547082
95Focal motor seizures (HP:0011153)1.68544554
96Aplasia/Hypoplasia of the optic nerve (HP:0008058)1.67895941
97Cerebellar dysplasia (HP:0007033)1.67568813
98Preaxial hand polydactyly (HP:0001177)1.67446905
99Chorioretinal atrophy (HP:0000533)1.66164195
100Agitation (HP:0000713)1.64957638
101Focal seizures (HP:0007359)1.64891155
102Abnormality of the proximal phalanges of the hand (HP:0009834)1.64049309
103Poor coordination (HP:0002370)1.64011359
104Renal dysplasia (HP:0000110)1.63094761
105Short tibia (HP:0005736)1.62292870
106Increased CSF lactate (HP:0002490)1.62026481
107Progressive macrocephaly (HP:0004481)1.61614033
108Broad-based gait (HP:0002136)1.61089320
109Aplasia/Hypoplasia of the lens (HP:0008063)1.60474476
110Small hand (HP:0200055)1.60129706
111Constricted visual fields (HP:0001133)1.57934847
112Abnormality of the nasal septum (HP:0000419)1.57456708
113Abnormality of the middle phalanx of the 5th finger (HP:0004219)1.56508029
114Pili torti (HP:0003777)1.54575800
115Aganglionic megacolon (HP:0002251)1.54262307
116Specific learning disability (HP:0001328)1.53164106
117Sclerocornea (HP:0000647)1.52647318
118Abnormality of renal excretion (HP:0011036)1.50204505
119Male pseudohermaphroditism (HP:0000037)1.49366314
120Anencephaly (HP:0002323)1.45594900
121Retinal dysplasia (HP:0007973)1.42675604
122Microglossia (HP:0000171)1.42529641
123Bell-shaped thorax (HP:0001591)1.42222588
124Aplasia/Hypoplasia of the fibula (HP:0006492)1.40566584
125Abnormal spermatogenesis (HP:0008669)1.40408536
126Recurrent bronchitis (HP:0002837)1.37482862
127Abnormal urine output (HP:0012590)1.32126050
128Polyuria (HP:0000103)1.31163709
129Atelectasis (HP:0100750)1.27104509
130Nephropathy (HP:0000112)1.26951327
131Short nail (HP:0001799)1.24038551
132Transposition of the great arteries (HP:0001669)1.21122318
133Abnormal connection of the cardiac segments (HP:0011545)1.21122318
134Abnormal ventriculo-arterial connection (HP:0011563)1.21122318
135Short ribs (HP:0000773)1.20381462
136Neonatal short-limb short stature (HP:0008921)1.19722814
137Furrowed tongue (HP:0000221)1.17470003
138Degeneration of the lateral corticospinal tracts (HP:0002314)1.17228367
139Atrophy/Degeneration involving the corticospinal tracts (HP:0007372)1.17228367
14011 pairs of ribs (HP:0000878)1.11693110
141Polycystic kidney dysplasia (HP:0000113)1.08911297
142Retinitis pigmentosa (HP:0000510)1.08691582
143Short thorax (HP:0010306)1.08238528
144Hypotelorism (HP:0000601)1.07924622
145Abnormal sex determination (HP:0012244)1.06643154
146Sex reversal (HP:0012245)1.06643154
147Gonadotropin excess (HP:0000837)1.05608504

Predicted kinase interactions (KEA)

RankGene SetZ-score
1PDK37.24280774
2PDK47.24280774
3PNCK4.84632206
4PDK24.68208210
5MAPK154.18348291
6PRKD34.11546438
7TESK13.85108392
8MST43.06624467
9ADRBK22.95963267
10MAP4K22.69482100
11BMPR1B2.63431467
12WNK32.33724520
13ICK2.24097684
14TLK12.13574115
15ZAK2.07489503
16PTK2B2.01869340
17INSRR2.01780962
18NUAK11.79823359
19ACVR1B1.73970504
20WNK41.71157979
21MAP3K41.69715162
22STK391.62766598
23OXSR11.60097039
24MUSK1.58721267
25TXK1.57175183
26IRAK21.45908477
27TYRO31.43155107
28STK101.37891391
29TAOK31.26406460
30DYRK21.22022834
31BCKDK1.21415842
32PLK21.19575717
33MAP2K71.16954902
34NTRK21.14976807
35DAPK21.05307273
36ARAF1.04195051
37IRAK11.01391801
38GRK11.00807816
39MKNK20.97662072
40NTRK30.96968896
41CAMKK20.95475451
42TIE10.95424986
43PIK3CA0.95229322
44MARK10.94690707
45STK380.93243660
46PRKCG0.90532062
47WEE10.90470321
48CDK190.85476280
49WNK10.85425199
50CDK30.84471634
51LMTK20.83646548
52NME10.81814638
53GRK70.81580391
54PLK40.81489257
55PHKG20.80428466
56PHKG10.80428466
57CSNK1G20.79560494
58TRIM280.77922479
59PASK0.76218587
60FGFR20.74857131
61VRK10.72218353
62DYRK1B0.70948116
63PDK10.69033613
64MAPKAPK30.68009082
65TGFBR10.67336080
66SGK20.65056334
67CAMK10.63654986
68MAP3K20.62787475
69EPHA40.62538884
70CSNK1G10.62012271
71PKN10.61672448
72NEK20.61508461
73MYLK0.60944596
74PAK20.60719865
75PIM20.60124477
76OBSCN0.59626339
77CCNB10.58223975
78SGK4940.56847559
79SGK2230.56847559
80BRAF0.56224564
81BRSK20.55436290
82TEC0.55409379
83CSNK1G30.55302793
84RPS6KA50.54706370
85STK110.53118865
86TNIK0.50854561
87MARK30.50343759
88CSNK1A10.50203262
89STK38L0.49390879
90KIT0.47747097
91SIK10.47389765
92PAK30.47349811
93MAP2K20.46415572
94STK30.43514250
95CSNK1A1L0.42821260
96ERBB20.42216107
97STK160.42180536
98DYRK1A0.42092456
99LRRK20.41608489
100TTK0.40480113
101PIK3CG0.39899207
102ERBB30.39546281
103IKBKB0.39294558
104EEF2K0.39263409
105NEK60.39226311
106ROCK10.37787730
107PLK10.37753358
108TRPM70.36403991
109PRKCE0.36114855
110PRKCQ0.34875887
111DYRK30.34809952
112SGK10.34144081
113NLK0.33125499
114ROCK20.32716905
115PRKCH0.32592540
116CASK0.32449089
117TNK20.32142251
118MAPKAPK50.31113979
119BCR0.30194110
120MAP3K90.29287080
121CAMKK10.29051362
122PDPK10.29048378
123AURKA0.27117834
124GSK3A0.26751618
125CHEK20.26490688
126PRKG10.24889541
127RPS6KA20.24349439
128AKT20.23627468
129CDC70.23406263
130CAMK1G0.22611175
131GRK50.22465455
132PRKACB0.21927984
133PRKACG0.21554808
134ADRBK10.21036349
135PRKACA0.20328691
136MAPK70.20015044
137ERBB40.19197384
138PAK10.19060111
139PRKCI0.18985238
140PRKAA10.18919944
141CAMK2G0.17994233
142ATM0.17481630
143CAMK2A0.16692510
144FRK0.16642574
145MAPK120.14890941
146PRKD20.13688985
147MAPK130.13519726
148PRKCA0.13507227
149CDK60.13235198
150CHEK10.12793429
151MKNK10.12224652
152CSNK1E0.11995112
153FER0.11291403
154MINK10.10804696
155MAPK100.10693821
156PINK10.10400655
157SRC0.08140275
158PRKCZ0.08083517

Predicted pathways (KEGG)

RankGene SetZ-score
1Vitamin B6 metabolism_Homo sapiens_hsa007505.07862736
2Pyruvate metabolism_Homo sapiens_hsa006203.11098550
3Fatty acid biosynthesis_Homo sapiens_hsa000613.10812321
4Propanoate metabolism_Homo sapiens_hsa006402.96358051
5Glycolysis / Gluconeogenesis_Homo sapiens_hsa000102.85685431
6PPAR signaling pathway_Homo sapiens_hsa033202.84483939
7Huntingtons disease_Homo sapiens_hsa050162.68601277
8Olfactory transduction_Homo sapiens_hsa047402.49604828
9Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005632.49217495
10Drug metabolism - cytochrome P450_Homo sapiens_hsa009822.32546551
11Glucagon signaling pathway_Homo sapiens_hsa049222.05667325
12Neuroactive ligand-receptor interaction_Homo sapiens_hsa040802.02744112
13Maturity onset diabetes of the young_Homo sapiens_hsa049501.96507538
14Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006011.93460516
15Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001301.86095361
16Nitrogen metabolism_Homo sapiens_hsa009101.84603710
17Synthesis and degradation of ketone bodies_Homo sapiens_hsa000721.83688788
18Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009801.70963286
19alpha-Linolenic acid metabolism_Homo sapiens_hsa005921.68450462
20Fatty acid degradation_Homo sapiens_hsa000711.68190640
21Vasopressin-regulated water reabsorption_Homo sapiens_hsa049621.67636135
22Steroid hormone biosynthesis_Homo sapiens_hsa001401.66277220
23Linoleic acid metabolism_Homo sapiens_hsa005911.65473060
24Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049641.64625346
25Protein export_Homo sapiens_hsa030601.58396226
26Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005331.56547923
27Amphetamine addiction_Homo sapiens_hsa050311.55341482
28Caffeine metabolism_Homo sapiens_hsa002321.52133185
29Primary bile acid biosynthesis_Homo sapiens_hsa001201.52060210
30Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006031.50307472
31Chemical carcinogenesis_Homo sapiens_hsa052041.44456317
32Dorso-ventral axis formation_Homo sapiens_hsa043201.43878932
33Cardiac muscle contraction_Homo sapiens_hsa042601.38483620
34Ascorbate and aldarate metabolism_Homo sapiens_hsa000531.37433523
35RNA polymerase_Homo sapiens_hsa030201.36615807
36Homologous recombination_Homo sapiens_hsa034401.34575714
37Hedgehog signaling pathway_Homo sapiens_hsa043401.34432701
38Basal transcription factors_Homo sapiens_hsa030221.33989741
39Glutathione metabolism_Homo sapiens_hsa004801.31036842
40Pentose phosphate pathway_Homo sapiens_hsa000301.27320392
41Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005121.23881014
42Ether lipid metabolism_Homo sapiens_hsa005651.23089963
43Glycerolipid metabolism_Homo sapiens_hsa005611.21833361
44Fatty acid metabolism_Homo sapiens_hsa012121.21492282
45Butanoate metabolism_Homo sapiens_hsa006501.19992786
46Retinol metabolism_Homo sapiens_hsa008301.16287717
47Collecting duct acid secretion_Homo sapiens_hsa049661.11985031
48Selenocompound metabolism_Homo sapiens_hsa004501.09593580
49Oxidative phosphorylation_Homo sapiens_hsa001901.07900647
50Mineral absorption_Homo sapiens_hsa049781.05297558
51Histidine metabolism_Homo sapiens_hsa003401.04865484
52Glycerophospholipid metabolism_Homo sapiens_hsa005641.04632737
53Serotonergic synapse_Homo sapiens_hsa047261.02919865
54Ribosome_Homo sapiens_hsa030101.01936310
55Purine metabolism_Homo sapiens_hsa002301.01800155
56Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049321.01551543
57Gastric acid secretion_Homo sapiens_hsa049711.00853829
58Pentose and glucuronate interconversions_Homo sapiens_hsa000401.00098586
59Arachidonic acid metabolism_Homo sapiens_hsa005900.99963506
60Carbon metabolism_Homo sapiens_hsa012000.99902930
61Insulin secretion_Homo sapiens_hsa049110.98704560
62Oocyte meiosis_Homo sapiens_hsa041140.95948351
63RNA degradation_Homo sapiens_hsa030180.95396788
64Basal cell carcinoma_Homo sapiens_hsa052170.95069947
65Carbohydrate digestion and absorption_Homo sapiens_hsa049730.94913209
66Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.94031751
67Retrograde endocannabinoid signaling_Homo sapiens_hsa047230.93836031
68Peroxisome_Homo sapiens_hsa041460.92124708
69Fructose and mannose metabolism_Homo sapiens_hsa000510.90279132
70Renin secretion_Homo sapiens_hsa049240.90116893
71Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.89165312
72Thyroid hormone synthesis_Homo sapiens_hsa049180.88096674
73Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.87662884
74Bile secretion_Homo sapiens_hsa049760.87461726
75Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.86229066
76Sulfur metabolism_Homo sapiens_hsa009200.85604139
77Alzheimers disease_Homo sapiens_hsa050100.81600479
78Estrogen signaling pathway_Homo sapiens_hsa049150.79712941
79Calcium signaling pathway_Homo sapiens_hsa040200.78451919
80Circadian rhythm_Homo sapiens_hsa047100.77932873
81Circadian entrainment_Homo sapiens_hsa047130.77067048
82Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.72813385
83Intestinal immune network for IgA production_Homo sapiens_hsa046720.72538293
84Taste transduction_Homo sapiens_hsa047420.70827962
85Parkinsons disease_Homo sapiens_hsa050120.70605302
86cGMP-PKG signaling pathway_Homo sapiens_hsa040220.70407954
87cAMP signaling pathway_Homo sapiens_hsa040240.70297529
88Salivary secretion_Homo sapiens_hsa049700.69928873
89Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010400.69090581
90Phototransduction_Homo sapiens_hsa047440.68150749
91ABC transporters_Homo sapiens_hsa020100.68103884
92Glycosaminoglycan degradation_Homo sapiens_hsa005310.66396219
93Tyrosine metabolism_Homo sapiens_hsa003500.65312597
94Citrate cycle (TCA cycle)_Homo sapiens_hsa000200.63087897
95Nicotine addiction_Homo sapiens_hsa050330.61754545
96Cocaine addiction_Homo sapiens_hsa050300.61663663
97Butirosin and neomycin biosynthesis_Homo sapiens_hsa005240.61503400
98Cysteine and methionine metabolism_Homo sapiens_hsa002700.61326499
99Sulfur relay system_Homo sapiens_hsa041220.61228528
100Vitamin digestion and absorption_Homo sapiens_hsa049770.59459192
101beta-Alanine metabolism_Homo sapiens_hsa004100.59017792
102Cytokine-cytokine receptor interaction_Homo sapiens_hsa040600.56355686
103Steroid biosynthesis_Homo sapiens_hsa001000.56080830
104Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.56019931
105Regulation of autophagy_Homo sapiens_hsa041400.55527944
106Taurine and hypotaurine metabolism_Homo sapiens_hsa004300.54980387
107Metabolic pathways_Homo sapiens_hsa011000.53378049
108Valine, leucine and isoleucine degradation_Homo sapiens_hsa002800.51448823
109Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.48061670
110Glutamatergic synapse_Homo sapiens_hsa047240.47758056
111Ovarian steroidogenesis_Homo sapiens_hsa049130.47579987
112Melanogenesis_Homo sapiens_hsa049160.47549937
113Tryptophan metabolism_Homo sapiens_hsa003800.46812192
114Fanconi anemia pathway_Homo sapiens_hsa034600.46168133
115Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.45948081
116Biosynthesis of amino acids_Homo sapiens_hsa012300.44079518
117Adipocytokine signaling pathway_Homo sapiens_hsa049200.43383814
118Fat digestion and absorption_Homo sapiens_hsa049750.43373213
119Cholinergic synapse_Homo sapiens_hsa047250.43067589
120Cytosolic DNA-sensing pathway_Homo sapiens_hsa046230.43033454
121Starch and sucrose metabolism_Homo sapiens_hsa005000.40353915
122Long-term potentiation_Homo sapiens_hsa047200.40140819
123Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042610.40138790
124Complement and coagulation cascades_Homo sapiens_hsa046100.39770041
125Pyrimidine metabolism_Homo sapiens_hsa002400.39490533
126Antigen processing and presentation_Homo sapiens_hsa046120.39302451
127One carbon pool by folate_Homo sapiens_hsa006700.39016718
128Primary immunodeficiency_Homo sapiens_hsa053400.38999691
129Asthma_Homo sapiens_hsa053100.38300920
130Alcoholism_Homo sapiens_hsa050340.38258137
131Phenylalanine metabolism_Homo sapiens_hsa003600.37090389
132Synaptic vesicle cycle_Homo sapiens_hsa047210.36178906
133Wnt signaling pathway_Homo sapiens_hsa043100.35699557
134Nucleotide excision repair_Homo sapiens_hsa034200.34733797
135Type I diabetes mellitus_Homo sapiens_hsa049400.34486822
136Dopaminergic synapse_Homo sapiens_hsa047280.34435323
137Morphine addiction_Homo sapiens_hsa050320.34083321
138GABAergic synapse_Homo sapiens_hsa047270.33847803

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