SNX30

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1axon ensheathment in central nervous system (GO:0032291)9.95548112
2central nervous system myelination (GO:0022010)9.95548112
3axon ensheathment (GO:0008366)6.46560262
4ensheathment of neurons (GO:0007272)6.46560262
5myelination (GO:0042552)6.46486819
6long-chain fatty acid biosynthetic process (GO:0042759)5.80597302
7negative regulation of neurotransmitter secretion (GO:0046929)5.37789444
8fatty acid elongation (GO:0030497)5.33956665
9negative regulation of neurotransmitter transport (GO:0051589)4.85743255
10L-amino acid import (GO:0043092)4.60576142
11presynaptic membrane organization (GO:0097090)4.47632590
12myelin maintenance (GO:0043217)4.46072873
13presynaptic membrane assembly (GO:0097105)4.36784930
14oligodendrocyte differentiation (GO:0048709)4.20239156
15establishment of mitochondrion localization (GO:0051654)4.14613947
16neuron cell-cell adhesion (GO:0007158)4.00987633
17response to lipoprotein particle (GO:0055094)4.00068284
18glycerophospholipid catabolic process (GO:0046475)3.90976115
19positive regulation of oligodendrocyte differentiation (GO:0048714)3.89365941
20import into cell (GO:0098657)3.81989266
21regulation of collateral sprouting (GO:0048670)3.80212740
22asymmetric protein localization (GO:0008105)3.70450888
23response to methylmercury (GO:0051597)3.63317413
24adult walking behavior (GO:0007628)3.62553559
25transmission of nerve impulse (GO:0019226)3.60292430
26astrocyte development (GO:0014002)3.59329141
27amino acid import (GO:0043090)3.56415275
28negative regulation of peptidyl-threonine phosphorylation (GO:0010801)3.44942326
29apical protein localization (GO:0045176)3.43143319
30virion attachment to host cell (GO:0019062)3.43026146
31adhesion of symbiont to host cell (GO:0044650)3.43026146
32negative regulation of protein localization to cell surface (GO:2000009)3.42732559
33positive regulation of cellular amide metabolic process (GO:0034250)3.40733673
34protein palmitoylation (GO:0018345)3.40484560
35photoreceptor cell differentiation (GO:0046530)3.38665507
36eye photoreceptor cell differentiation (GO:0001754)3.38665507
37surfactant homeostasis (GO:0043129)3.35344776
38response to redox state (GO:0051775)3.32863255
39dendritic spine morphogenesis (GO:0060997)3.31883886
40negative regulation of axonogenesis (GO:0050771)3.31239038
41neuronal action potential propagation (GO:0019227)3.28519401
42cholesterol biosynthetic process (GO:0006695)3.27641180
43nerve growth factor signaling pathway (GO:0038180)3.25676837
44peptidyl-tyrosine autophosphorylation (GO:0038083)3.25086480
45magnesium ion transport (GO:0015693)3.22327903
46positive regulation of action potential (GO:0045760)3.19243968
47activated T cell proliferation (GO:0050798)3.16056053
48myelination in peripheral nervous system (GO:0022011)3.14307940
49peripheral nervous system axon ensheathment (GO:0032292)3.14307940
50Golgi to endosome transport (GO:0006895)3.11916109
51cerebral cortex radially oriented cell migration (GO:0021799)3.09419920
52neuronal ion channel clustering (GO:0045161)3.06474569
53cellular extravasation (GO:0045123)3.06297507
54regulation of ARF protein signal transduction (GO:0032012)3.06202815
55neuron remodeling (GO:0016322)3.06074411
56locomotory exploration behavior (GO:0035641)3.05872979
57establishment of nucleus localization (GO:0040023)3.04448409
58lipid translocation (GO:0034204)3.03554985
59phospholipid translocation (GO:0045332)3.03554985
60neuron recognition (GO:0008038)2.98758687
61cerebellar granule cell differentiation (GO:0021707)2.96487443
62dendrite morphogenesis (GO:0048813)2.95191382
63amyloid precursor protein metabolic process (GO:0042982)2.94690265
64phosphatidylinositol-3-phosphate biosynthetic process (GO:0036092)2.94118117
65substantia nigra development (GO:0021762)2.94112651
66cellular response to ethanol (GO:0071361)2.93533342
67L-serine transport (GO:0015825)2.92681207
68creatine metabolic process (GO:0006600)2.90660610
69negative regulation of axon extension (GO:0030517)2.90180241
70regulation of beta-amyloid formation (GO:1902003)2.89924174
71sterol biosynthetic process (GO:0016126)2.86704146
72positive regulation of leukocyte degranulation (GO:0043302)2.82061174
73chemical homeostasis within a tissue (GO:0048875)2.82024304
74glycosylceramide metabolic process (GO:0006677)2.81711446
75membrane tubulation (GO:0097320)2.81283553
76clathrin coat assembly (GO:0048268)2.76984214
77axonal fasciculation (GO:0007413)2.76028288
78positive regulation of mast cell activation (GO:0033005)2.74875647
79leukocyte migration involved in inflammatory response (GO:0002523)2.73779100
80gamma-aminobutyric acid signaling pathway (GO:0007214)2.69242315
81organ growth (GO:0035265)2.68770635
82neutrophil activation involved in immune response (GO:0002283)2.68297916
83negative regulation of synaptic transmission, GABAergic (GO:0032229)2.66696216
84regulation of N-methyl-D-aspartate selective glutamate receptor activity (GO:2000310)2.66365894
85cellular response to epinephrine stimulus (GO:0071872)2.66363381
86ionotropic glutamate receptor signaling pathway (GO:0035235)2.65616900
87regulation of synaptic vesicle exocytosis (GO:2000300)2.65026427
88positive regulation of regulated secretory pathway (GO:1903307)2.63190953
89negative regulation of macroautophagy (GO:0016242)2.62680802
90positive regulation of mast cell activation involved in immune response (GO:0033008)2.62335134
91positive regulation of mast cell degranulation (GO:0043306)2.62335134
92detection of molecule of bacterial origin (GO:0032490)2.61282073
93positive regulation of glial cell differentiation (GO:0045687)2.61198507
94histone H2B ubiquitination (GO:0033523)2.60798114
95negative regulation of JUN kinase activity (GO:0043508)2.60023001
96negative regulation of amyloid precursor protein catabolic process (GO:1902992)2.59806477
97synaptic vesicle docking involved in exocytosis (GO:0016081)2.59188682
98histone H3-K36 demethylation (GO:0070544)2.57189042
99serine transport (GO:0032329)2.56946365
100cellular response to catecholamine stimulus (GO:0071870)2.55847207
101cellular response to monoamine stimulus (GO:0071868)2.55847207
102membrane assembly (GO:0071709)2.55808948
103synaptic vesicle maturation (GO:0016188)2.54771934
104establishment of mitochondrion localization, microtubule-mediated (GO:0034643)2.51797569
105mitochondrion transport along microtubule (GO:0047497)2.51797569
106glial cell development (GO:0021782)2.51492415
107mating behavior (GO:0007617)2.50117442
108protein localization to endosome (GO:0036010)2.48753354
109positive regulation of gliogenesis (GO:0014015)2.48117206
110isoprenoid biosynthetic process (GO:0008299)2.47260852
111GPI anchor metabolic process (GO:0006505)2.47057684
112regulation of regulated secretory pathway (GO:1903305)2.46262424
113Golgi to plasma membrane protein transport (GO:0043001)2.45712718
114neurotransmitter uptake (GO:0001504)2.45712565
115negative regulation of exocytosis (GO:0045920)2.44000234
116negative regulation of synaptic transmission (GO:0050805)2.43779144
117long-chain fatty-acyl-CoA biosynthetic process (GO:0035338)2.40357772
118positive regulation of excitatory postsynaptic membrane potential (GO:2000463)2.40048414
119axon development (GO:0061564)2.39995332
120peripheral nervous system development (GO:0007422)2.39643023
121GPI anchor biosynthetic process (GO:0006506)2.38661252
122cortical actin cytoskeleton organization (GO:0030866)2.38454158
123regulation of synaptic vesicle transport (GO:1902803)2.38400700
124phosphatidylinositol 3-kinase signaling (GO:0014065)2.37830336
125adult locomotory behavior (GO:0008344)2.37427934
126response to hepatocyte growth factor (GO:0035728)2.37208913
127regulation of protein glycosylation (GO:0060049)2.37184380
128regulation of leukocyte degranulation (GO:0043300)2.35503894
129regulation of short-term neuronal synaptic plasticity (GO:0048172)2.34462549
130positive regulation of myeloid leukocyte mediated immunity (GO:0002888)2.34129921
131positive regulation of nitric-oxide synthase biosynthetic process (GO:0051770)2.33398443
132positive regulation of Rap GTPase activity (GO:0032854)2.33295107
133regulation of Rac protein signal transduction (GO:0035020)2.32288556
134neurotransmitter-gated ion channel clustering (GO:0072578)2.30029940
135cerebellar Purkinje cell differentiation (GO:0021702)2.29400214
136macrophage activation involved in immune response (GO:0002281)2.28869557
137cellular response to thyroid hormone stimulus (GO:0097067)2.28733042
138early endosome to late endosome transport (GO:0045022)2.28341587
139glutamate secretion (GO:0014047)2.24794124
140peptidyl-threonine phosphorylation (GO:0018107)2.24492119
141regulation of cellular amide metabolic process (GO:0034248)2.24230808
142regulation of mast cell activation (GO:0033003)2.22672734
143suckling behavior (GO:0001967)2.21881641
144regulation of Rap GTPase activity (GO:0032317)2.18020588
145negative regulation of dendrite morphogenesis (GO:0050774)2.17438600
146response to nerve growth factor (GO:1990089)2.17417252
147cellular response to nerve growth factor stimulus (GO:1990090)2.17417252
148melanin biosynthetic process (GO:0042438)2.16122167
149glycosphingolipid catabolic process (GO:0046479)2.12958190
150regulation of amyloid precursor protein catabolic process (GO:1902991)2.12913160
151cytoplasmic mRNA processing body assembly (GO:0033962)2.12625719
152regulation of myeloid leukocyte mediated immunity (GO:0002886)2.12496893
153protein targeting to lysosome (GO:0006622)2.12110250
154establishment of protein localization to vacuole (GO:0072666)2.12110250
155protein targeting to vacuole (GO:0006623)2.12110250
156peptidyl-threonine modification (GO:0018210)2.10444082
157cytoskeletal anchoring at plasma membrane (GO:0007016)2.09594623
158cortical cytoskeleton organization (GO:0030865)2.09066901
159regulation of mast cell activation involved in immune response (GO:0033006)2.06313171
160macroautophagy (GO:0016236)2.05866357
161proline transport (GO:0015824)2.04842153
162regulation of mast cell degranulation (GO:0043304)2.04170039
163positive regulation of receptor recycling (GO:0001921)2.03657324
164response to laminar fluid shear stress (GO:0034616)2.03320174
165Rap protein signal transduction (GO:0032486)2.02247096
166positive regulation of exocytosis (GO:0045921)2.01247554
167regulation of macrophage cytokine production (GO:0010935)1.98312777
168melanin metabolic process (GO:0006582)1.97716863
169exploration behavior (GO:0035640)1.97291070
170pyrimidine nucleobase catabolic process (GO:0006208)1.96820520
171regulation of pigment cell differentiation (GO:0050932)1.96594297
172nucleus localization (GO:0051647)1.96530224
173developmental pigmentation (GO:0048066)1.96052143
174negative regulation of complement activation (GO:0045916)1.95939561
175positive regulation of glycoprotein biosynthetic process (GO:0010560)1.95482281
176positive regulation of macrophage cytokine production (GO:0060907)1.95183326
177regulation of dendritic spine development (GO:0060998)1.94896413
178oligosaccharide catabolic process (GO:0009313)1.94714007

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1GBX2_23144817_ChIP-Seq_PC3_Human3.62664516
2EZH2_22144423_ChIP-Seq_EOC_Human3.51312517
3* VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human2.61755749
4* SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse2.49035917
5JARID2_20064375_ChIP-Seq_MESCs_Mouse2.34926216
6SUZ12_18692474_ChIP-Seq_MESCs_Mouse2.32529777
7SUZ12_18555785_ChIP-Seq_MESCs_Mouse2.24536731
8DROSHA_22980978_ChIP-Seq_HELA_Human2.22051092
9AR_21572438_ChIP-Seq_LNCaP_Human2.14735736
10Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse2.13096005
11TAF15_26573619_Chip-Seq_HEK293_Human2.10932100
12CEBPD_23245923_ChIP-Seq_MEFs_Mouse2.05685570
13* OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse2.00717350
14RNF2_18974828_ChIP-Seq_MESCs_Mouse2.00527502
15EZH2_18974828_ChIP-Seq_MESCs_Mouse2.00527502
16MTF2_20144788_ChIP-Seq_MESCs_Mouse1.96162051
17SUZ12_20075857_ChIP-Seq_MESCs_Mouse1.87609139
18BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse1.84998908
19SUZ12_18692474_ChIP-Seq_MEFs_Mouse1.81004006
20SUZ12_18974828_ChIP-Seq_MESCs_Mouse1.80423785
21CDX2_19796622_ChIP-Seq_MESCs_Mouse1.78099649
22EZH2_27304074_Chip-Seq_ESCs_Mouse1.76847400
23EZH2_27294783_Chip-Seq_ESCs_Mouse1.72513209
24WT1_19549856_ChIP-ChIP_CCG9911_Human1.72384229
25SUZ12_16625203_ChIP-ChIP_MESCs_Mouse1.71074007
26* RARB_27405468_Chip-Seq_BRAIN_Mouse1.69940217
27RNF2_27304074_Chip-Seq_ESCs_Mouse1.68988586
28ER_23166858_ChIP-Seq_MCF-7_Human1.65673883
29ZFP57_27257070_Chip-Seq_ESCs_Mouse1.65152920
30SUZ12_27294783_Chip-Seq_ESCs_Mouse1.64825949
31ZFP322A_24550733_ChIP-Seq_MESCs_Mouse1.64357493
32PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.61175125
33* IRF8_27001747_Chip-Seq_BMDM_Mouse1.60714348
34EED_16625203_ChIP-ChIP_MESCs_Mouse1.59877402
35REST_21632747_ChIP-Seq_MESCs_Mouse1.58820336
36SMAD3_21741376_ChIP-Seq_EPCs_Human1.58768658
37JARID2_20075857_ChIP-Seq_MESCs_Mouse1.58449483
38CTBP1_25329375_ChIP-Seq_LNCAP_Human1.57098869
39GLI1_17442700_ChIP-ChIP_MESCs_Mouse1.56558983
40STAT6_20620947_ChIP-Seq_CD4_POS_T_Human1.56303962
41VDR_24787735_ChIP-Seq_THP-1_Human1.55140625
42STAT6_21828071_ChIP-Seq_BEAS2B_Human1.50719575
43NFE2L2_20460467_ChIP-Seq_MEFs_Mouse1.49354449
44NRF2_20460467_ChIP-Seq_MEFs_Mouse1.49354449
45TP53_16413492_ChIP-PET_HCT116_Human1.48955429
46STAT3_24763339_ChIP-Seq_IMN-ESCs_Mouse1.48798254
47SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse1.48707754
48FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse1.46080823
49POU3F2_20337985_ChIP-ChIP_501MEL_Human1.45219677
50NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse1.44795381
51STAT3_23295773_ChIP-Seq_U87_Human1.42074782
52SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.41962958
53TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.40773677
54SALL1_21062744_ChIP-ChIP_HESCs_Human1.39982064
55STAT3_20064451_ChIP-Seq_CD4+T_Mouse1.38511915
56RNF2_16625203_ChIP-ChIP_MESCs_Mouse1.36506822
57P53_22127205_ChIP-Seq_FIBROBLAST_Human1.35890544
58MYB_21317192_ChIP-Seq_ERMYB_Mouse1.35036151
59PPARG_20176806_ChIP-Seq_MACROPHAGES_Mouse1.32658152
60P300_19829295_ChIP-Seq_ESCs_Human1.32339148
61CTBP2_25329375_ChIP-Seq_LNCAP_Human1.31725695
62FUS_26573619_Chip-Seq_HEK293_Human1.27454880
63SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.26862544
64AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human1.26311129
65PIAS1_25552417_ChIP-Seq_VCAP_Human1.26155318
66NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse1.25298709
67WT1_25993318_ChIP-Seq_PODOCYTE_Human1.24898967
68NFE2L2_22581777_ChIP-Seq_LYMPHOBLASTOID_Human1.24556794
69* TCF4_23295773_ChIP-Seq_U87_Human1.23799885
70TCF3_18467660_ChIP-ChIP_MESCs_Mouse1.21517565
71ARNT_22903824_ChIP-Seq_MCF-7_Human1.20635679
72REST_18959480_ChIP-ChIP_MESCs_Mouse1.19887442
73AHR_22903824_ChIP-Seq_MCF-7_Human1.19090896
74SMAD4_21799915_ChIP-Seq_A2780_Human1.18507911
75YAP1_20516196_ChIP-Seq_MESCs_Mouse1.16871889
76FOXO3_23340844_ChIP-Seq_DLD1_Human1.16074877
77ZNF217_24962896_ChIP-Seq_MCF-7_Human1.14370986
78CMYC_18555785_Chip-Seq_ESCs_Mouse1.14021873
79PHC1_16625203_ChIP-ChIP_MESCs_Mouse1.13831571
80TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse1.13594483
81CEBPD_21427703_ChIP-Seq_3T3-L1_Mouse1.13039767
82GATA2_21666600_ChIP-Seq_HMVEC_Human1.12853117
83SOX2_21211035_ChIP-Seq_LN229_Gbm1.12638187
84NANOG_18555785_Chip-Seq_ESCs_Mouse1.12165096
85FOXA1_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human1.11553589
86TCF4_18268006_ChIP-ChIP_LS174T_Human1.10948341
87FOXP3_17237761_ChIP-ChIP_TREG_Mouse1.10622632
88* FOXA2_19822575_ChIP-Seq_HepG2_Human1.10218804
89RUNX_20019798_ChIP-Seq_JUKART_Human1.09609052
90SMAD3_22036565_ChIP-Seq_ESCs_Mouse1.09537089
91SMAD3_21741376_ChIP-Seq_HESCs_Human1.09383367
92FOXM1_26456572_ChIP-Seq_MCF-7_Human1.09319881
93LMO2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.08921664
94* EP300_21415370_ChIP-Seq_HL-1_Mouse1.08130969
95CTNNB1_20460455_ChIP-Seq_HCT116_Human1.07560595
96BMI1_23680149_ChIP-Seq_NPCS_Mouse1.06249966
97SOX9_22984422_ChIP-ChIP_TESTIS_Rat1.05948067
98NR3C1_21868756_ChIP-Seq_MCF10A_Human1.05139534
99SOX9_26525672_Chip-Seq_Limbbuds_Mouse1.04560355
100CBX2_27304074_Chip-Seq_ESCs_Mouse1.04273077
101STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse1.02955047
102E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse1.02907960
103MEIS1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse1.02429200
104DMRT1_23473982_ChIP-Seq_TESTES_Mouse1.02399697
105POU5F1_26923725_Chip-Seq_MESODERM_Mouse1.01954458
106TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.01954458
107ERA_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human1.01942852
108CDX2_21402776_ChIP-Seq_INTESTINAL-VILLUS_Mouse1.01440826
109AR_25329375_ChIP-Seq_VCAP_Human1.01162201
110TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human1.01116199
111PRDM14_20953172_ChIP-Seq_ESCs_Human1.00894714
112EOMES_21245162_ChIP-Seq_HESCs_Human1.00881750
113TOP2B_26459242_ChIP-Seq_MCF-7_Human1.00274112
114* RUNX2_22187159_ChIP-Seq_PCA_Human1.00138782
115GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.00108199
116RING1B_27294783_Chip-Seq_NPCs_Mouse0.99450874
117LMO2_26923725_Chip-Seq_MACROPHAGESS_Mouse0.99445920
118KDM2B_26808549_Chip-Seq_REH_Human0.99304139
119ESR1_20079471_ChIP-ChIP_T-47D_Human0.98835608
120SOX9_24532713_ChIP-Seq_HFSC_Mouse0.98723436
121* IRF8_21731497_ChIP-ChIP_J774_Mouse0.98630979
122RXR_22108803_ChIP-Seq_LS180_Human0.98474815
123CEBPB_26923725_Chip-Seq_MESODERM_Mouse0.98448798
124GATA1_26923725_Chip-Seq_HPCs_Mouse0.97919045
125SUZ12_18555785_Chip-Seq_ESCs_Mouse0.97609673
126WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse0.97516611
127BRD4_25478319_ChIP-Seq_HGPS_Human0.97285587
128* TEAD4_22529382_ChIP-Seq_TROPHECTODERM_Mouse0.97187288
129P300_18555785_Chip-Seq_ESCs_Mouse0.97090959
130FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse0.96896722
131RNF2_27304074_Chip-Seq_NSC_Mouse0.96887772
132P53_22387025_ChIP-Seq_ESCs_Mouse0.96715804
133EWS_26573619_Chip-Seq_HEK293_Human0.96428084
134IRF8_22096565_ChIP-ChIP_GC-B_Human0.95185714
135ESR1_22446102_ChIP-Seq_UTERUS_Mouse0.94181245
136NR3C1_23031785_ChIP-Seq_PC12_Mouse0.91603132
137MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse0.91330074
138PCGF2_27294783_Chip-Seq_NPCs_Mouse0.90819437
139E2F1_18555785_Chip-Seq_ESCs_Mouse0.89998716
140TFAP2C_20629094_ChIP-Seq_MCF-7_Human0.89837627
141SMAD_19615063_ChIP-ChIP_OVARY_Human0.89485258
142EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse0.89443799
143TBL1_22424771_ChIP-Seq_293T_Human0.88422382
144IGF1R_20145208_ChIP-Seq_DFB_Human0.87549533
145UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human0.87387576

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0000920_abnormal_myelination5.07237683
2MP0003880_abnormal_central_pattern4.07770594
3MP0003690_abnormal_glial_cell3.31038441
4MP0004270_analgesia3.24960696
5MP0004859_abnormal_synaptic_plasticity3.24795759
6MP0004742_abnormal_vestibular_system2.85233263
7MP0001958_emphysema2.78048647
8MP0004885_abnormal_endolymph2.73356138
9MP0001486_abnormal_startle_reflex2.63559481
10MP0002064_seizures2.57960585
11MP0003950_abnormal_plasma_membrane2.52458336
12MP0002272_abnormal_nervous_system2.48611161
13MP0003634_abnormal_glial_cell2.42692276
14MP0003329_amyloid_beta_deposits2.40773452
15MP0003635_abnormal_synaptic_transmissio2.37830375
16MP0000778_abnormal_nervous_system2.37822126
17MP0010234_abnormal_vibrissa_follicle2.35939408
18MP0005409_darkened_coat_color2.34849770
19MP0009046_muscle_twitch2.33682708
20MP0001905_abnormal_dopamine_level2.30043758
21MP0005423_abnormal_somatic_nervous2.23162843
22MP0005171_absent_coat_pigmentation2.18456832
23MP0003172_abnormal_lysosome_physiology2.11457697
24MP0009745_abnormal_behavioral_response2.06547971
25MP0003191_abnormal_cellular_cholesterol2.03264002
26MP0003632_abnormal_nervous_system2.02002961
27MP0004142_abnormal_muscle_tone2.01869523
28MP0001986_abnormal_taste_sensitivity1.97273058
29MP0001529_abnormal_vocalization1.93346331
30MP0002229_neurodegeneration1.92277695
31MP0001485_abnormal_pinna_reflex1.84764586
32MP0001440_abnormal_grooming_behavior1.84545758
33MP0000371_diluted_coat_color1.81882006
34MP0002572_abnormal_emotion/affect_behav1.81411413
35MP0002877_abnormal_melanocyte_morpholog1.78148407
36MP0002734_abnormal_mechanical_nocicepti1.77025409
37MP0003136_yellow_coat_color1.76090609
38MP0005058_abnormal_lysosome_morphology1.74917803
39MP0002063_abnormal_learning/memory/cond1.69524925
40MP0010386_abnormal_urinary_bladder1.68458086
41MP0005408_hypopigmentation1.64947947
42MP0004782_abnormal_surfactant_physiolog1.64797038
43MP0000462_abnormal_digestive_system1.63515008
44MP0003091_abnormal_cell_migration1.63492935
45MP0000955_abnormal_spinal_cord1.62997709
46MP0008569_lethality_at_weaning1.62508808
47MP0003300_gastrointestinal_ulcer1.61947081
48MP0003828_pulmonary_edema1.61025006
49MP0010352_gastrointestinal_tract_polyps1.56666242
50MP0005257_abnormal_intraocular_pressure1.56173171
51MP0000604_amyloidosis1.56093398
52MP0010678_abnormal_skin_adnexa1.55808161
53MP0002067_abnormal_sensory_capabilities1.50644308
54MP0003724_increased_susceptibility_to1.48796559
55MP0002882_abnormal_neuron_morphology1.48676362
56MP0004134_abnormal_chest_morphology1.46534858
57MP0003631_nervous_system_phenotype1.42442893
58MP0002009_preneoplasia1.39554741
59MP0002066_abnormal_motor_capabilities/c1.39102158
60MP0005248_abnormal_Harderian_gland1.36344049
61MP0002998_abnormal_bone_remodeling1.35878633
62MP0000383_abnormal_hair_follicle1.34810900
63MP0005386_behavior/neurological_phenoty1.33141834
64MP0004924_abnormal_behavior1.33141834
65MP0008260_abnormal_autophagy1.32238699
66MP0001970_abnormal_pain_threshold1.31784452
67MP0004883_abnormal_blood_vessel1.27109281
68MP0001299_abnormal_eye_distance/1.25843403
69MP0001963_abnormal_hearing_physiology1.21941541
70MP0002733_abnormal_thermal_nociception1.21578431
71MP0004145_abnormal_muscle_electrophysio1.21403887
72MP0003633_abnormal_nervous_system1.20265775
73MP0002909_abnormal_adrenal_gland1.13298114
74MP0004381_abnormal_hair_follicle1.13289851
75MP0005645_abnormal_hypothalamus_physiol1.12352358
76MP0003122_maternal_imprinting1.12271174
77MP0005075_abnormal_melanosome_morpholog1.11922845
78MP0000747_muscle_weakness1.11111497
79MP0003879_abnormal_hair_cell1.10658352
80MP0002419_abnormal_innate_immunity1.10303542
81MP0002152_abnormal_brain_morphology1.08659976
82MP0002752_abnormal_somatic_nervous1.03433767
83MP0002184_abnormal_innervation1.03115268
84MP0001177_atelectasis1.02970624
85MP0000569_abnormal_digit_pigmentation1.01369891
86MP0005410_abnormal_fertilization1.00083983
87MP0003075_altered_response_to0.99588128
88MP0004811_abnormal_neuron_physiology0.99121393
89MP0008057_abnormal_DNA_replication0.98544886
90MP0003183_abnormal_peptide_metabolism0.97726274
91MP0005551_abnormal_eye_electrophysiolog0.97118431
92MP0003121_genomic_imprinting0.95660780
93MP0003123_paternal_imprinting0.95473008
94MP0002557_abnormal_social/conspecific_i0.94701456
95MP0002090_abnormal_vision0.94586875
96MP0002095_abnormal_skin_pigmentation0.93355826
97MP0003303_peritoneal_inflammation0.93247943
98MP0001968_abnormal_touch/_nociception0.93203748
99MP0009780_abnormal_chondrocyte_physiolo0.90963190
100MP0000631_abnormal_neuroendocrine_gland0.89358380
101MP0005623_abnormal_meninges_morphology0.89185825
102MP0001984_abnormal_olfaction0.89002887
103MP0003938_abnormal_ear_development0.88321157
104MP0000427_abnormal_hair_cycle0.87119194
105MP0001851_eye_inflammation0.87086084
106MP0003787_abnormal_imprinting0.86872394
107MP0005310_abnormal_salivary_gland0.86703618
108MP0002075_abnormal_coat/hair_pigmentati0.86107742
109MP0001324_abnormal_eye_pigmentation0.85745220
110MP0001501_abnormal_sleep_pattern0.81870986
111MP0000015_abnormal_ear_pigmentation0.81250113
112MP0003045_fibrosis0.80864170
113MP0001661_extended_life_span0.79754389
114MP0005195_abnormal_posterior_eye0.78209002
115MP0002735_abnormal_chemical_nociception0.77091784
116MP0003705_abnormal_hypodermis_morpholog0.76854035
117MP0001348_abnormal_lacrimal_gland0.75143351
118MP0001186_pigmentation_phenotype0.74616624
119MP0005076_abnormal_cell_differentiation0.74142006
120MP0001502_abnormal_circadian_rhythm0.73898006
121MP0006054_spinal_hemorrhage0.72795398
122MP0002133_abnormal_respiratory_system0.71518105
123MP0005388_respiratory_system_phenotype0.71518105
124MP0003890_abnormal_embryonic-extraembry0.71499107
125MP0001727_abnormal_embryo_implantation0.70519683
126MP0004133_heterotaxia0.68763331
127MP0009115_abnormal_fat_cell0.68553758
128MP0004043_abnormal_pH_regulation0.68512772
129MP0005646_abnormal_pituitary_gland0.68397018
130MP0005451_abnormal_body_composition0.68326101
131MP0000465_gastrointestinal_hemorrhage0.68158292
132MP0005387_immune_system_phenotype0.67456474
133MP0001790_abnormal_immune_system0.67456474
134MP0000003_abnormal_adipose_tissue0.65675632
135MP0000026_abnormal_inner_ear0.65348381
136MP0005174_abnormal_tail_pigmentation0.64951183
137MP0001835_abnormal_antigen_presentation0.64447936
138MP0003861_abnormal_nervous_system0.64371982
139MP0002295_abnormal_pulmonary_circulatio0.64069157
140MP0004185_abnormal_adipocyte_glucose0.63003032
141MP0000372_irregular_coat_pigmentation0.62677013
142MP0006082_CNS_inflammation0.62580986
143MP0003937_abnormal_limbs/digits/tail_de0.62505602
144MP0005164_abnormal_response_to0.61894088
145MP0000647_abnormal_sebaceous_gland0.60478129

Predicted human phenotypes

RankGene SetZ-score
1Degeneration of the lateral corticospinal tracts (HP:0002314)6.44763096
2Atrophy/Degeneration involving the corticospinal tracts (HP:0007372)6.44763096
3Neurofibrillary tangles (HP:0002185)6.35614075
4Abnormality of the corticospinal tract (HP:0002492)5.19663206
5Supranuclear gaze palsy (HP:0000605)4.83602526
6Cerebral inclusion bodies (HP:0100314)4.82773580
7Sensory axonal neuropathy (HP:0003390)4.61362664
8Peripheral hypomyelination (HP:0007182)4.38621654
9Parakeratosis (HP:0001036)4.19100552
10Spastic gait (HP:0002064)3.97556426
11Onion bulb formation (HP:0003383)3.60821048
12Akinesia (HP:0002304)3.55598119
13Dysmetria (HP:0001310)3.52092076
14Intention tremor (HP:0002080)3.48978360
15Intracellular accumulation of autofluorescent lipopigment storage material (HP:0003204)3.46857490
16Interstitial pulmonary disease (HP:0006530)3.30693927
17Abnormal auditory evoked potentials (HP:0006958)3.28837244
18Alacrima (HP:0000522)3.18945714
19Scanning speech (HP:0002168)3.12937947
20Slow saccadic eye movements (HP:0000514)3.09136382
21Insidious onset (HP:0003587)3.04858726
22Termporal pattern (HP:0011008)3.04858726
23Cerebral hypomyelination (HP:0006808)3.02297056
24Eczematoid dermatitis (HP:0000976)2.95546222
25Recurrent gram-negative bacterial infections (HP:0005420)2.92704405
26Anteriorly placed anus (HP:0001545)2.91278315
27Vacuolated lymphocytes (HP:0001922)2.87798827
28Ankle clonus (HP:0011448)2.87749257
29Recurrent abscess formation (HP:0002722)2.87170990
30Congenital nonbullous ichthyosiform erythroderma (HP:0007479)2.86026990
31Decreased lacrimation (HP:0000633)2.81621207
32Abnormality of macrophages (HP:0004311)2.71796587
33Clumsiness (HP:0002312)2.71177181
34Bowel incontinence (HP:0002607)2.61340949
35Papillary thyroid carcinoma (HP:0002895)2.60789567
36Febrile seizures (HP:0002373)2.59778371
37Ocular albinism (HP:0001107)2.54267852
38Widely spaced teeth (HP:0000687)2.52245211
39Abnormal large intestine physiology (HP:0012700)2.52095032
40Myokymia (HP:0002411)2.50791162
41Premature skin wrinkling (HP:0100678)2.50133810
42Disinhibition (HP:0000734)2.49449009
43Recurrent bacterial skin infections (HP:0005406)2.48223146
44Blue irides (HP:0000635)2.46029901
45Neuronal loss in central nervous system (HP:0002529)2.45278626
46Atonic seizures (HP:0010819)2.44790458
47Thickened helices (HP:0000391)2.43728694
48Broad-based gait (HP:0002136)2.41381440
49Hypoplastic pelvis (HP:0008839)2.40936238
50Dysostosis multiplex (HP:0000943)2.40325621
51Inappropriate behavior (HP:0000719)2.39730639
52Lower limb muscle weakness (HP:0007340)2.39586197
53Retinal dysplasia (HP:0007973)2.37920353
54Apathy (HP:0000741)2.36254289
55Iris hypopigmentation (HP:0007730)2.32911676
56Focal seizures (HP:0007359)2.31962194
57Small epiphyses (HP:0010585)2.28245191
58Hematochezia (HP:0002573)2.27564454
59Generalized hypopigmentation of hair (HP:0011358)2.27408842
60Morphological abnormality of the inner ear (HP:0011390)2.27000837
61Action tremor (HP:0002345)2.21438554
62Gingivitis (HP:0000230)2.19808214
63Mutism (HP:0002300)2.19282899
64Arterial tortuosity (HP:0005116)2.16336812
65Subacute progressive viral hepatitis (HP:0006572)2.15283664
66Periodontitis (HP:0000704)2.14627015
67Overgrowth (HP:0001548)2.13587108
68Diminished motivation (HP:0000745)2.12444559
69Focal motor seizures (HP:0011153)2.10845828
70Cupped ear (HP:0000378)2.06665248
71Spondylolisthesis (HP:0003302)2.06518373
72Increased cerebral lipofuscin (HP:0011813)2.06279631
73Increased neuronal autofluorescent lipopigment (HP:0002074)2.05895912
74Partial agenesis of the corpus callosum (HP:0001338)2.04848849
75Hypokalemic alkalosis (HP:0001949)2.04206064
76Gaze-evoked nystagmus (HP:0000640)2.03966923
77Urinary glycosaminoglycan excretion (HP:0003541)2.03850094
78Mucopolysacchariduria (HP:0008155)2.03850094
79Amyloidosis (HP:0011034)2.03732288
80Increased circulating renin level (HP:0000848)2.03378142
81Absent speech (HP:0001344)2.02760992
82Relative macrocephaly (HP:0004482)2.02722942
83Urinary incontinence (HP:0000020)2.01560837
84Urinary bladder sphincter dysfunction (HP:0002839)2.01434194
85Urinary urgency (HP:0000012)2.00874607
86Cerebral aneurysm (HP:0004944)1.99966283
87Bilateral sensorineural hearing impairment (HP:0008619)1.99202933
88Morphological abnormality of the pyramidal tract (HP:0002062)1.97180275
89Decreased motor nerve conduction velocity (HP:0003431)1.96964970
90Excessive salivation (HP:0003781)1.95937155
91Drooling (HP:0002307)1.95937155
92CNS hypomyelination (HP:0003429)1.95147854
93Generalized myoclonic seizures (HP:0002123)1.94570270
94Metabolic alkalosis (HP:0200114)1.94483753
95Autoamputation (HP:0001218)1.92685936
96Stridor (HP:0010307)1.92343575
97Papilledema (HP:0001085)1.92119998
98Agitation (HP:0000713)1.91911097
99Absent frontal sinuses (HP:0002688)1.91753986
100Vascular tortuosity (HP:0004948)1.91626683
101Loss of speech (HP:0002371)1.90698912
102Spastic paraparesis (HP:0002313)1.89860050
103Macroorchidism (HP:0000053)1.89658784
104Abnormality of mucopolysaccharide metabolism (HP:0011020)1.89299810
105Abnormality of polysaccharide metabolism (HP:0011012)1.89299810
106Abnormality of glycosaminoglycan metabolism (HP:0004371)1.89299810
107Gastrointestinal stroma tumor (HP:0100723)1.89097539
108Hip dysplasia (HP:0001385)1.88497786
109Spastic tetraparesis (HP:0001285)1.88241382
110Agammaglobulinemia (HP:0004432)1.87612469
111Clonus (HP:0002169)1.86294238
112Dialeptic seizures (HP:0011146)1.85736737
113Epileptic encephalopathy (HP:0200134)1.85463633
114Paraparesis (HP:0002385)1.83900866
115Overriding aorta (HP:0002623)1.83348282
116Transitional cell carcinoma of the bladder (HP:0006740)1.83241143
117Aqueductal stenosis (HP:0002410)1.81724816
118Segmental peripheral demyelination/remyelination (HP:0003481)1.81680973
119Absent septum pellucidum (HP:0001331)1.81467888
120Increased CSF protein (HP:0002922)1.81371073
121Generalized hypopigmentation (HP:0007513)1.80765312
122Dysdiadochokinesis (HP:0002075)1.79133368
123Hypoplasia of the iris (HP:0007676)1.78660587
124Myocardial infarction (HP:0001658)1.78655144
125Abnormality of liposaccharide metabolism (HP:0010968)1.78607173
126Abnormality of glycosphingolipid metabolism (HP:0004343)1.78607173
127Abnormality of glycolipid metabolism (HP:0010969)1.78607173
128Postural instability (HP:0002172)1.77211403
129Truncal ataxia (HP:0002078)1.76845265
130Peripheral demyelination (HP:0011096)1.76590271
131Abnormality of the parathyroid morphology (HP:0011766)1.76067226
132Esophageal atresia (HP:0002032)1.75818887
133Split foot (HP:0001839)1.75577224
134Progressive cerebellar ataxia (HP:0002073)1.75288169
135Bladder neoplasm (HP:0009725)1.75235189
136Bladder carcinoma (HP:0002862)1.75235189
137Abnormality of the periventricular white matter (HP:0002518)1.73876580
138Abnormality of binocular vision (HP:0011514)1.73169341
139Diplopia (HP:0000651)1.73169341
140Diminished movement (HP:0002374)1.72604716
141Global brain atrophy (HP:0002283)1.71586494
142Tubulointerstitial fibrosis (HP:0005576)1.71217389
143Asymmetry of the thorax (HP:0001555)1.70780857
144Large earlobe (HP:0009748)1.70555219
145Infantile muscular hypotonia (HP:0008947)1.70231007
146Pheochromocytoma (HP:0002666)1.69939199
147Hyperventilation (HP:0002883)1.69379685
148Spastic paraplegia (HP:0001258)1.68405645
149Neoplasm of the heart (HP:0100544)1.68096468
150Distal sensory impairment (HP:0002936)1.68073868
151Congenital ichthyosiform erythroderma (HP:0007431)1.67661979
152Frequent falls (HP:0002359)1.66471712
153Hemiplegia (HP:0002301)1.63826377
154Spontaneous hematomas (HP:0007420)1.63654676
155Elevated circulating parathyroid hormone (PTH) level (HP:0003165)1.61812245
156Neoplasm of the adrenal cortex (HP:0100641)1.61806659
157Recurrent skin infections (HP:0001581)1.61199284
158Germ cell neoplasia (HP:0100728)1.60501536
159Osteolytic defects of the hand bones (HP:0009699)1.60423293
160Osteolytic defects of the phalanges of the hand (HP:0009771)1.60423293
161Aplasia/Hypoplasia of the frontal sinuses (HP:0009119)1.60368346
162Striae distensae (HP:0001065)1.59319477
163Dysmetric saccades (HP:0000641)1.58964236
164Thyroid carcinoma (HP:0002890)1.57857188

Predicted kinase interactions (KEA)

RankGene SetZ-score
1STK394.87650014
2OXSR13.99732053
3EPHB13.33181327
4TNIK2.91261835
5FRK2.79836031
6PKN12.68725918
7CDK192.55982812
8PNCK2.46312244
9MAPKAPK52.22727327
10FGFR22.07978495
11WNK12.03297645
12SGK21.98256754
13MARK11.90771090
14UHMK11.87257936
15PRPF4B1.81016476
16SGK31.80469036
17FGFR31.76883356
18FES1.73132630
19ICK1.69319709
20NTRK11.68849883
21KSR11.67656945
22PAK61.65787451
23NEK61.63299665
24CLK11.60709272
25BCR1.58940290
26CSNK1G31.55687429
27CSNK1A1L1.50177147
28LIMK11.46674364
29FGR1.45243614
30WNK41.40567028
31DAPK21.40077731
32MET1.36347743
33TYK21.35412903
34TYRO31.34063035
35ACVR1B1.32916534
36CAMK1D1.31488718
37CAMK2B1.31203311
38CSNK1G21.30666695
39MARK21.29705434
40TGFBR21.29538643
41ROCK21.28935866
42BLK1.28783991
43KSR21.26237412
44CSNK1G11.21797730
45CAMK1G1.18649575
46LATS11.17386140
47STK38L1.17305612
48JAK11.15071018
49AKT31.14678568
50LATS21.13798427
51STK381.12196053
52MAPK151.09580023
53SIK31.09530046
54MAP3K131.07922258
55PAK31.07515398
56EPHA41.06866903
57MAP3K91.05654209
58NEK91.04891789
59PRKD31.04318372
60NTRK31.03827110
61CSF1R0.99096625
62CASK0.98333676
63FER0.97994330
64RET0.97883814
65CDK50.96784161
66SGK2230.95278673
67SGK4940.95278673
68MAP3K60.94982888
69MAPK130.91919090
70CAMK2D0.91165284
71PDGFRA0.87623907
72NLK0.87127074
73FYN0.83720064
74CAMKK10.83210483
75HIPK20.81271897
76PRKCQ0.81028225
77JAK20.80783325
78NTRK20.80430579
79ERBB30.78920793
80CDK140.78831915
81MAP3K140.78048221
82CDK150.76583365
83CDK60.74861310
84MAP2K40.74782872
85PBK0.74224754
86DYRK20.73916816
87MAP3K10.73612420
88STK110.72437163
89RPS6KA20.72158847
90ERBB20.71726104
91ZAP700.71714398
92IRAK20.71053975
93PRKD10.70650705
94PDGFRB0.69519660
95CSK0.68982439
96CDK180.68975995
97TESK20.68364622
98SIK20.67876815
99CDK11A0.66052572
100STK240.65054611
101RIPK40.62367171
102CDK120.61759584
103CAMK2A0.61473493
104EPHA30.60631149
105CSNK1D0.60316885
106PINK10.60041545
107RIPK10.59191331
108PLK20.58975603
109PDPK10.58099196
110DYRK1A0.55851257
111MINK10.54794692
112TRPM70.52632940
113CDC42BPA0.52294678
114PRKCH0.52291528
115CAMK2G0.52110205
116PRKCE0.51154210
117PRKCZ0.51084710
118MAPK120.49990681
119PRKG10.49154318
120ALK0.49120550
121MAP3K20.48614324
122PKN20.48609859
123MKNK10.47771651
124FGFR10.47752543
125IRAK40.47377059
126CAMK40.46893904
127LCK0.45837736
128INSR0.45286759
129MAPK70.44945806
130MST40.44498954
131HCK0.43462971
132BRD40.43336217
133PDK10.42764945
134ADRBK20.42025808
135MAPK100.41401462
136MAP3K40.41231778
137MAP4K10.38996591
138IRAK10.37723428
139SGK10.37677009
140ITK0.37336252
141BMPR20.37016900
142GSK3A0.36324037
143PAK20.35508811
144DMPK0.35435652
145MELK0.34535626
146CAMKK20.33340848
147RPS6KA50.33314552
148YES10.32104319

Predicted pathways (KEGG)

RankGene SetZ-score
1Terpenoid backbone biosynthesis_Homo sapiens_hsa009004.09913633
2Steroid biosynthesis_Homo sapiens_hsa001003.29041813
3Ether lipid metabolism_Homo sapiens_hsa005652.55159441
4Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005632.52407827
5Fatty acid elongation_Homo sapiens_hsa000622.19477047
6Synthesis and degradation of ketone bodies_Homo sapiens_hsa000722.18395472
7Axon guidance_Homo sapiens_hsa043602.11645468
8Glutamatergic synapse_Homo sapiens_hsa047241.90856581
9Sphingolipid metabolism_Homo sapiens_hsa006001.81487592
10GABAergic synapse_Homo sapiens_hsa047271.62848759
11Renal cell carcinoma_Homo sapiens_hsa052111.62166429
12Serotonergic synapse_Homo sapiens_hsa047261.61731370
13Long-term depression_Homo sapiens_hsa047301.60133492
14Nicotine addiction_Homo sapiens_hsa050331.59271286
15Morphine addiction_Homo sapiens_hsa050321.57355111
16Retrograde endocannabinoid signaling_Homo sapiens_hsa047231.56436358
17B cell receptor signaling pathway_Homo sapiens_hsa046621.51271601
18Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046661.49371237
19Butirosin and neomycin biosynthesis_Homo sapiens_hsa005241.44721023
20Cell adhesion molecules (CAMs)_Homo sapiens_hsa045141.44583105
21Staphylococcus aureus infection_Homo sapiens_hsa051501.34307018
22Circadian entrainment_Homo sapiens_hsa047131.28240996
23Lysosome_Homo sapiens_hsa041421.26710076
24Dorso-ventral axis formation_Homo sapiens_hsa043201.24801462
25Phospholipase D signaling pathway_Homo sapiens_hsa040721.24647706
26Endometrial cancer_Homo sapiens_hsa052131.24486878
27Cocaine addiction_Homo sapiens_hsa050301.23134781
28Glycosaminoglycan degradation_Homo sapiens_hsa005311.21643284
29Sphingolipid signaling pathway_Homo sapiens_hsa040711.20927302
30Tuberculosis_Homo sapiens_hsa051521.20805350
31Phosphatidylinositol signaling system_Homo sapiens_hsa040701.20312430
32Neurotrophin signaling pathway_Homo sapiens_hsa047221.19771462
33Synaptic vesicle cycle_Homo sapiens_hsa047211.19115657
34Vitamin B6 metabolism_Homo sapiens_hsa007501.18894637
35Endocytosis_Homo sapiens_hsa041441.17940695
36mTOR signaling pathway_Homo sapiens_hsa041501.17931172
37Dopaminergic synapse_Homo sapiens_hsa047281.17578109
38Cholinergic synapse_Homo sapiens_hsa047251.17131015
39ErbB signaling pathway_Homo sapiens_hsa040121.16841875
40Regulation of lipolysis in adipocytes_Homo sapiens_hsa049231.15237439
41Leishmaniasis_Homo sapiens_hsa051401.14830754
42Collecting duct acid secretion_Homo sapiens_hsa049661.13656331
43Long-term potentiation_Homo sapiens_hsa047201.13526421
44Salivary secretion_Homo sapiens_hsa049701.13396384
45Vibrio cholerae infection_Homo sapiens_hsa051101.11629557
46AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049331.10087842
47Taurine and hypotaurine metabolism_Homo sapiens_hsa004301.09404798
48Taste transduction_Homo sapiens_hsa047421.07985852
49Non-small cell lung cancer_Homo sapiens_hsa052231.05795606
50Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051201.04519256
51Gastric acid secretion_Homo sapiens_hsa049711.03163965
52Amphetamine addiction_Homo sapiens_hsa050311.02574147
53Prolactin signaling pathway_Homo sapiens_hsa049171.00215307
54Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.99144269
55Ras signaling pathway_Homo sapiens_hsa040140.93777493
56Choline metabolism in cancer_Homo sapiens_hsa052310.93538752
57Adherens junction_Homo sapiens_hsa045200.92187713
58Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047500.91638745
59Regulation of actin cytoskeleton_Homo sapiens_hsa048100.91165963
60Colorectal cancer_Homo sapiens_hsa052100.89716912
61Chronic myeloid leukemia_Homo sapiens_hsa052200.88110589
62Carbohydrate digestion and absorption_Homo sapiens_hsa049730.87416634
63Protein export_Homo sapiens_hsa030600.87110831
64Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.86815191
65Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.86697171
66Vascular smooth muscle contraction_Homo sapiens_hsa042700.84345718
67Thyroid hormone signaling pathway_Homo sapiens_hsa049190.83390273
68VEGF signaling pathway_Homo sapiens_hsa043700.82902061
69Phagosome_Homo sapiens_hsa041450.82031728
70Chemokine signaling pathway_Homo sapiens_hsa040620.81158968
71Pertussis_Homo sapiens_hsa051330.80880037
72FoxO signaling pathway_Homo sapiens_hsa040680.80867240
73Amoebiasis_Homo sapiens_hsa051460.80381581
74Inositol phosphate metabolism_Homo sapiens_hsa005620.80316028
75SNARE interactions in vesicular transport_Homo sapiens_hsa041300.79726812
76Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049600.79380025
77Olfactory transduction_Homo sapiens_hsa047400.78641548
78Rheumatoid arthritis_Homo sapiens_hsa053230.78438477
79Pancreatic secretion_Homo sapiens_hsa049720.78343292
80MAPK signaling pathway_Homo sapiens_hsa040100.77562987
81Renin secretion_Homo sapiens_hsa049240.76584144
82Type II diabetes mellitus_Homo sapiens_hsa049300.76485372
83Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046500.76458542
84Chagas disease (American trypanosomiasis)_Homo sapiens_hsa051420.76403745
85Linoleic acid metabolism_Homo sapiens_hsa005910.75920870
86Gap junction_Homo sapiens_hsa045400.75030900
87Proteoglycans in cancer_Homo sapiens_hsa052050.73807154
88Vasopressin-regulated water reabsorption_Homo sapiens_hsa049620.73650596
89Oxytocin signaling pathway_Homo sapiens_hsa049210.73018374
90Longevity regulating pathway - mammal_Homo sapiens_hsa042110.72634028
91Pancreatic cancer_Homo sapiens_hsa052120.70973916
92Alcoholism_Homo sapiens_hsa050340.70059721
93Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010400.70050012
94alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.69144590
95Insulin secretion_Homo sapiens_hsa049110.69084549
96Focal adhesion_Homo sapiens_hsa045100.68570570
97Toxoplasmosis_Homo sapiens_hsa051450.68316886
98Bacterial invasion of epithelial cells_Homo sapiens_hsa051000.67910402
99GnRH signaling pathway_Homo sapiens_hsa049120.67009843
100Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.66570660
101cAMP signaling pathway_Homo sapiens_hsa040240.66393270
102Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.64840863
103Ovarian steroidogenesis_Homo sapiens_hsa049130.63915294
104Estrogen signaling pathway_Homo sapiens_hsa049150.63460473
105T cell receptor signaling pathway_Homo sapiens_hsa046600.63086812
106Glycerophospholipid metabolism_Homo sapiens_hsa005640.62913166
107Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042610.62351260
108Tight junction_Homo sapiens_hsa045300.62013840
109Aldosterone synthesis and secretion_Homo sapiens_hsa049250.61972396
110Acute myeloid leukemia_Homo sapiens_hsa052210.61473706
111Calcium signaling pathway_Homo sapiens_hsa040200.59167786
112Toll-like receptor signaling pathway_Homo sapiens_hsa046200.59084665
113Fc epsilon RI signaling pathway_Homo sapiens_hsa046640.58967558
114Other glycan degradation_Homo sapiens_hsa005110.57335433
115Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.57003571
116Thyroid hormone synthesis_Homo sapiens_hsa049180.55837462
117Glioma_Homo sapiens_hsa052140.54374511
118Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049610.54229688
119Platelet activation_Homo sapiens_hsa046110.53766767
120Non-homologous end-joining_Homo sapiens_hsa034500.49718687
121Phototransduction_Homo sapiens_hsa047440.48736182
122Malaria_Homo sapiens_hsa051440.46632843
123Sulfur metabolism_Homo sapiens_hsa009200.45497079
124Primary immunodeficiency_Homo sapiens_hsa053400.45384090
125Butanoate metabolism_Homo sapiens_hsa006500.45094358
126cGMP-PKG signaling pathway_Homo sapiens_hsa040220.42773821
127Leukocyte transendothelial migration_Homo sapiens_hsa046700.41984171
128Prostate cancer_Homo sapiens_hsa052150.41432350
129Rap1 signaling pathway_Homo sapiens_hsa040150.39865933
130Melanogenesis_Homo sapiens_hsa049160.39559893
131Wnt signaling pathway_Homo sapiens_hsa043100.38508605
132Osteoclast differentiation_Homo sapiens_hsa043800.38338951

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