SMCR8

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1modulation by organism of immune response of other organism involved in symbiotic interaction (GO:004.38536411
2modulation by organism of defense response of other organism involved in symbiotic interaction (GO:04.38536411
3positive regulation by organism of defense response of other organism involved in symbiotic interact4.38536411
4modulation by symbiont of host immune response (GO:0052553)4.38536411
5positive regulation by symbiont of host defense response (GO:0052509)4.38536411
6modulation by symbiont of host defense response (GO:0052031)4.38536411
7negative regulation of erythrocyte differentiation (GO:0045647)4.30412970
8regulation of interferon-beta biosynthetic process (GO:0045357)4.16925889
9response to peptidoglycan (GO:0032494)4.09239628
10antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G4.07524008
11positive regulation of gamma-delta T cell activation (GO:0046645)3.90380773
12macrophage activation involved in immune response (GO:0002281)3.63121497
13detection of other organism (GO:0098543)3.57599976
14antigen processing and presentation of endogenous peptide antigen via MHC class I (GO:0019885)3.57348140
15antigen processing and presentation of endogenous peptide antigen (GO:0002483)3.57348140
16cellular extravasation (GO:0045123)3.56184873
17histone H3-K36 demethylation (GO:0070544)3.51111672
18positive regulation of histone deacetylation (GO:0031065)3.48806719
19regulation of interleukin-12 biosynthetic process (GO:0045075)3.46912120
20regulation of gamma-delta T cell differentiation (GO:0045586)3.43194493
21detection of bacterium (GO:0016045)3.32729351
22cytoplasmic mRNA processing body assembly (GO:0033962)3.31130674
23regulation of gamma-delta T cell activation (GO:0046643)3.30167615
24positive regulation of interferon-alpha production (GO:0032727)3.28670719
25neutrophil activation involved in immune response (GO:0002283)3.26690464
26nuclear pore complex assembly (GO:0051292)3.25626598
27germinal center formation (GO:0002467)3.24181777
28embryonic process involved in female pregnancy (GO:0060136)3.22787790
29antigen processing and presentation of endogenous antigen (GO:0019883)3.22168447
30positive regulation of antigen receptor-mediated signaling pathway (GO:0050857)3.20597822
31regulation of interferon-alpha production (GO:0032647)3.19081214
32leukocyte aggregation (GO:0070486)3.18881735
33detection of molecule of bacterial origin (GO:0032490)3.18812977
34low-density lipoprotein particle clearance (GO:0034383)3.13474014
35NLS-bearing protein import into nucleus (GO:0006607)3.13266267
36I-kappaB phosphorylation (GO:0007252)3.10556528
37negative regulation of cell killing (GO:0031342)3.10382729
38negative regulation of leukocyte mediated cytotoxicity (GO:0001911)3.10382729
39T cell selection (GO:0045058)3.08916264
40detection of external biotic stimulus (GO:0098581)3.08363177
41positive regulation of membrane protein ectodomain proteolysis (GO:0051044)3.06366975
42pre-miRNA processing (GO:0031054)3.02551898
43regulation of leukocyte degranulation (GO:0043300)2.99979322
44positive T cell selection (GO:0043368)2.96987430
45negative T cell selection (GO:0043383)2.94277315
46positive regulation of nitric-oxide synthase biosynthetic process (GO:0051770)2.92274603
47JAK-STAT cascade involved in growth hormone signaling pathway (GO:0060397)2.90686904
48L-alpha-amino acid transmembrane transport (GO:1902475)2.89064463
49positive regulation of interleukin-2 biosynthetic process (GO:0045086)2.87586946
50regulation of cholesterol storage (GO:0010885)2.85857673
51macroautophagy (GO:0016236)2.84701430
52positive thymic T cell selection (GO:0045059)2.83553852
53positive regulation of interleukin-8 biosynthetic process (GO:0045416)2.82283560
54positive regulation of B cell differentiation (GO:0045579)2.82068543
55lipopolysaccharide-mediated signaling pathway (GO:0031663)2.81985775
56negative regulation of T cell mediated immunity (GO:0002710)2.81370488
57regulation of mast cell degranulation (GO:0043304)2.78825263
58negative regulation of lymphocyte mediated immunity (GO:0002707)2.76225908
59T cell migration (GO:0072678)2.75690407
60apoptotic cell clearance (GO:0043277)2.74991071
61tolerance induction (GO:0002507)2.74661069
62response to interleukin-15 (GO:0070672)2.73788111
63positive regulation of type I interferon-mediated signaling pathway (GO:0060340)2.72656431
64nuclear pore organization (GO:0006999)2.72607284
65detection of biotic stimulus (GO:0009595)2.72273099
66response to laminar fluid shear stress (GO:0034616)2.72135413
67regulation of myeloid leukocyte mediated immunity (GO:0002886)2.70537014
68positive regulation of tumor necrosis factor biosynthetic process (GO:0042535)2.70139217
69positive regulation of p38MAPK cascade (GO:1900745)2.66714993
70response to host (GO:0075136)2.66380380
71response to host defenses (GO:0052200)2.66380380
72response to defenses of other organism involved in symbiotic interaction (GO:0052173)2.66380380
73mannose metabolic process (GO:0006013)2.65282625
74regulation of histone H3-K27 methylation (GO:0061085)2.64881739
75negative regulation of granulocyte differentiation (GO:0030853)2.64281682
76positive regulation of cellular amide metabolic process (GO:0034250)2.64102189
77cell adhesion mediated by integrin (GO:0033627)2.63788999
78B cell homeostasis (GO:0001782)2.63028141
79negative regulation of leukocyte mediated immunity (GO:0002704)2.62957460
80growth hormone receptor signaling pathway (GO:0060396)2.61937197
81response to immune response of other organism involved in symbiotic interaction (GO:0052564)2.60258889
82response to host immune response (GO:0052572)2.60258889
83regulation of T-helper 2 cell differentiation (GO:0045628)2.59016912
84regulation of membrane protein ectodomain proteolysis (GO:0051043)2.57445759
85response to type I interferon (GO:0034340)2.57440985
86respiratory burst (GO:0045730)2.56877966
87type I interferon signaling pathway (GO:0060337)2.56510809
88cellular response to type I interferon (GO:0071357)2.56510809
89pore complex assembly (GO:0046931)2.55416203
90regulation of NFAT protein import into nucleus (GO:0051532)2.54223157
91response to muramyl dipeptide (GO:0032495)2.53761522
92regulation of T cell tolerance induction (GO:0002664)2.51695072
93regulation of necroptotic process (GO:0060544)2.51345887
94positive regulation of interferon-beta production (GO:0032728)2.50742874
95regulation of B cell receptor signaling pathway (GO:0050855)2.50566089
96pinocytosis (GO:0006907)2.50421419
97NIK/NF-kappaB signaling (GO:0038061)2.50390115
98regulation of mast cell activation involved in immune response (GO:0033006)2.49699824
99dicarboxylic acid biosynthetic process (GO:0043650)2.48489804
100negative regulation of lipopolysaccharide-mediated signaling pathway (GO:0031665)2.47937693
101protein localization to endosome (GO:0036010)2.47379552
102granulocyte activation (GO:0036230)2.46826036
103neutrophil activation (GO:0042119)2.46557645
104regulation of tolerance induction (GO:0002643)2.46520578
105defense response to protozoan (GO:0042832)2.45885643
106phospholipid homeostasis (GO:0055091)2.45542892
107regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S transition 2.44392879
108regulation of cholesterol homeostasis (GO:2000188)2.44283577
109regulation of tumor necrosis factor biosynthetic process (GO:0042534)2.44090180
110negative regulation of interleukin-6 production (GO:0032715)2.42094674
111natural killer cell mediated immunity (GO:0002228)2.41932707
112natural killer cell mediated cytotoxicity (GO:0042267)2.41932707
113production of molecular mediator involved in inflammatory response (GO:0002532)2.41638675
114regulation of regulated secretory pathway (GO:1903305)2.40791412
115response to protozoan (GO:0001562)2.38650405
1163-UTR-mediated mRNA stabilization (GO:0070935)2.38560857
117negative regulation of lipid storage (GO:0010888)2.38033859
118regulation of dendritic cell antigen processing and presentation (GO:0002604)2.37041455
119negative regulation of CD4-positive, alpha-beta T cell activation (GO:2000515)2.36701403
120mitotic sister chromatid cohesion (GO:0007064)2.36273389
121modification by symbiont of host morphology or physiology (GO:0044003)2.29837890
122lipoprotein transport (GO:0042953)2.29295908
123positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S tr2.27763191
124immunoglobulin mediated immune response (GO:0016064)2.26059776
125regulation of translational fidelity (GO:0006450)2.25703899
126regulation of integrin activation (GO:0033623)2.24725177
127regulation of protein polyubiquitination (GO:1902914)2.24453359
128positive regulation of protein deacetylation (GO:0090312)2.22876542
129regulation of RNA export from nucleus (GO:0046831)2.21528139
130B cell receptor signaling pathway (GO:0050853)2.20672858
131negative regulation of interleukin-12 production (GO:0032695)2.20017652
132response to UV-C (GO:0010225)2.19839265
133regulation of vascular endothelial growth factor signaling pathway (GO:1900746)2.18597461
134negative regulation of toll-like receptor signaling pathway (GO:0034122)2.18329587
135negative regulation of B cell proliferation (GO:0030889)2.16078012
136regulation of fatty acid beta-oxidation (GO:0031998)2.15813894
137glucocorticoid receptor signaling pathway (GO:0042921)2.15510528
138antigen processing and presentation via MHC class Ib (GO:0002475)2.15174326
139cortical actin cytoskeleton organization (GO:0030866)2.14976161
140cellular response to growth hormone stimulus (GO:0071378)2.14344579
141modulation by symbiont of host cellular process (GO:0044068)2.13884439
142corticosteroid receptor signaling pathway (GO:0031958)2.12901796
143mRNA stabilization (GO:0048255)2.12690980
144RNA stabilization (GO:0043489)2.12690980
145thymic T cell selection (GO:0045061)2.12686501
146negative thymic T cell selection (GO:0045060)2.11847712
147myeloid cell activation involved in immune response (GO:0002275)2.11797219
148regulation of type I interferon-mediated signaling pathway (GO:0060338)2.11209027
149regulation of B cell differentiation (GO:0045577)2.10511124
150regulation of nucleobase-containing compound transport (GO:0032239)2.10217177
151regulation of transcription from RNA polymerase II promoter in response to oxidative stress (GO:00432.09388996
152macrophage activation (GO:0042116)2.08894594
153peptidyl-lysine dimethylation (GO:0018027)2.08870071
154heterochromatin organization (GO:0070828)2.08598722
155positive regulation of protein import into nucleus, translocation (GO:0033160)2.06798461

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1EGR1_19374776_ChIP-ChIP_THP-1_Human4.78084116
2NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse4.38784556
3IRF8_22096565_ChIP-ChIP_GC-B_Human3.58528960
4E2F7_22180533_ChIP-Seq_HELA_Human3.36583976
5STAT6_20620947_ChIP-Seq_CD4_POS_T_Human3.00830356
6MYC_22102868_ChIP-Seq_BL_Human2.90822893
7FOXP3_17237761_ChIP-ChIP_TREG_Mouse2.82826912
8IRF8_21731497_ChIP-ChIP_J774_Mouse2.75038779
9SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse2.69913261
10FOXM1_23109430_ChIP-Seq_U2OS_Human2.69564961
11NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse2.64477720
12IRF8_27001747_Chip-Seq_BMDM_Mouse2.53017952
13STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse2.47352993
14MYB_21317192_ChIP-Seq_ERMYB_Mouse2.35940566
15* TCF7_22412390_ChIP-Seq_EML_Mouse2.27702133
16MECOM_23826213_ChIP-Seq_KASUMI_Mouse2.25806687
17BRD4_27068464_Chip-Seq_AML-cells_Mouse2.21497268
18ESR1_17901129_ChIP-ChIP_LIVER_Mouse2.20235445
19Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse2.14169221
20VDR_21846776_ChIP-Seq_THP-1_Human2.10838205
21IRF1_21803131_ChIP-Seq_MONOCYTES_Human2.09200294
22STAT3_20064451_ChIP-Seq_CD4+T_Mouse2.06346529
23KDM2B_26808549_Chip-Seq_HPB-ALL_Human2.01092903
24KDM2B_26808549_Chip-Seq_DND41_Human1.92230889
25PPARA_22158963_ChIP-Seq_LIVER_Mouse1.88407768
26MAF_26560356_Chip-Seq_TH1_Human1.88372011
27KDM2B_26808549_Chip-Seq_SIL-ALL_Human1.82195341
28RXR_22158963_ChIP-Seq_LIVER_Mouse1.79513289
29FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse1.79434301
30KDM2B_26808549_Chip-Seq_SUP-B15_Human1.78500758
31STAT6_21828071_ChIP-Seq_BEAS2B_Human1.76880556
32RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human1.75958011
33ASXL1_24218140_ChIP-Seq_BMDM_Mouse1.73015548
34GATA1_22025678_ChIP-Seq_K562_Human1.72233986
35LXR_22158963_ChIP-Seq_LIVER_Mouse1.71852031
36SCL_19346495_ChIP-Seq_HPC-7_Human1.68996090
37UTX_26944678_Chip-Seq_JUKART_Human1.67815446
38VDR_24763502_ChIP-Seq_THP-1_Human1.64423178
39* IRF8_22096565_ChIP-ChIP_GC-B_Mouse1.64224618
40MYB_26560356_Chip-Seq_TH1_Human1.63911344
41MYB_26560356_Chip-Seq_TH2_Human1.62130557
42E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human1.61595160
43RUNX_20019798_ChIP-Seq_JUKART_Human1.60752471
44SPI1_23127762_ChIP-Seq_K562_Human1.60287967
45ELK3_25401928_ChIP-Seq_HUVEC_Human1.58479351
46NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human1.55681416
47BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse1.55536491
48KLF6_26769127_Chip-Seq_PDAC-Cell_line_Human1.54415224
49FOXO3_23340844_ChIP-Seq_DLD1_Human1.52676453
50RUNX1_22412390_ChIP-Seq_EML_Mouse1.49304373
51CLOCK_20551151_ChIP-Seq_293T_Human1.47671839
52BP1_19119308_ChIP-ChIP_Hs578T_Human1.41226149
53TAL1_20566737_ChIP-Seq_PRIMARY_FETAL_LIVER_ERYTHROID_Mouse1.39081679
54PU_27001747_Chip-Seq_BMDM_Mouse1.37925388
55FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse1.28135867
56SPI1_22096565_ChIP-ChIP_GC-B_Mouse1.27489262
57PPARG_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse1.26189329
58NR1I2_20693526_ChIP-Seq_LIVER_Mouse1.25914945
59P300_27058665_Chip-Seq_ZR-75-30cells_Human1.25129284
60KDM2B_26808549_Chip-Seq_JURKAT_Human1.24753368
61SMAD_19615063_ChIP-ChIP_OVARY_Human1.24391017
62MEIS1_20887958_ChIP-Seq_HPC-7_Mouse1.24226063
63GATA1_22383799_ChIP-Seq_G1ME_Mouse1.23841625
64HIF1A_21447827_ChIP-Seq_MCF-7_Human1.22507602
65NFE2L2_22581777_ChIP-Seq_LYMPHOBLASTOID_Human1.22413325
66CEBPB_21427703_ChIP-Seq_3T3-L1_Mouse1.21583124
67VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human1.21009613
68NCOR1_26117541_ChIP-Seq_K562_Human1.20200485
69ESR2_21235772_ChIP-Seq_MCF-7_Human1.18939521
70ELF3_26769127_Chip-Seq_PDAC-Cell_line_Human1.18587573
71RUNX2_24764292_ChIP-Seq_MC3T3_Mouse1.18348499
72STAT4_19710469_ChIP-ChIP_TH1__Mouse1.18168197
73GATA3_27048872_Chip-Seq_THYMUS_Human1.17772364
74KLF4_26769127_Chip-Seq_PDAC-Cell_line_Human1.16500264
75GATA1_19941826_ChIP-Seq_K562_Human1.15964606
76TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse1.15319467
77* CEBPB_20176806_ChIP-Seq_MACROPHAGES_Mouse1.14730397
78TFAP2C_20629094_ChIP-Seq_MCF-7_Human1.13800319
79* TFEB_21752829_ChIP-Seq_HELA_Human1.13454609
80* PU.1_20513432_ChIP-Seq_MACROPHAGES_Mouse1.12872467
81GATA2_21571218_ChIP-Seq_MEGAKARYOCYTES_Human1.10021260
82FOXP2_23625967_ChIP-Seq_PFSK-1_AND_SK-N-MC_Human1.08852783
83CTCF_27219007_Chip-Seq_ERYTHROID_Human1.08816761
84TCF21_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human1.08230433
85FOXA1_26769127_Chip-Seq_PDAC-Cell_line_Human1.08005450
86ATF3_27146783_Chip-Seq_COLON_Human1.07681074
87THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse1.07576804
88CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat1.07415861
89* SPI1_23547873_ChIP-Seq_NB4_Human1.07334360
90SFPI1_20887958_ChIP-Seq_HPC-7_Mouse1.06833322
91DMRT1_23473982_ChIP-Seq_TESTES_Mouse1.05214630
92RUNX1_27514584_Chip-Seq_MCF-7_Human1.03323304
93GATA6_25053715_ChIP-Seq_YYC3_Human1.02082605
94* SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse1.01927914
95FOXA2_19822575_ChIP-Seq_HepG2_Human1.01590090
96TAF7L_23326641_ChIP-Seq_C3H10T1-2_Mouse1.00641825
97RUNX1_20887958_ChIP-Seq_HPC-7_Mouse1.00248758
98* CEBPB_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse1.00080212
99GATA2_22383799_ChIP-Seq_G1ME_Mouse0.99416486
100DACH1_20351289_ChIP-Seq_MDA-MB-231_Human0.98289362
101TP63_17297297_ChIP-ChIP_HaCaT_Human0.97340134
102* PU.1_20176806_ChIP-Seq_MACROPHAGES_Mouse0.97286386
103* GATA1_19941827_ChIP-Seq_MEL_Mouse0.96936158
104ZFP281_27345836_Chip-Seq_ESCs_Mouse0.96689036
105EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse0.96492315
106RARG_19884340_ChIP-ChIP_MEFs_Mouse0.96185649
107VDR_24787735_ChIP-Seq_THP-1_Human0.96065753
108MAF_26560356_Chip-Seq_TH2_Human0.95701104
109* PU.1_20513432_ChIP-Seq_Bcells_Mouse0.95657467
110PPAR_26484153_Chip-Seq_NCI-H1993_Human0.93590523
111SOX2_27498859_Chip-Seq_STOMACH_Mouse0.93372872
112SMARCA4_20176728_ChIP-ChIP_TSCs_Mouse0.92155296
113GATA2_19941826_ChIP-Seq_K562_Human0.92048485
114SMAD3_18955504_ChIP-ChIP_HaCaT_Human0.91749806
115SMAD2_18955504_ChIP-ChIP_HaCaT_Human0.91749806
116FOXO1_23066095_ChIP-Seq_LIVER_Mouse0.91073301
117SCL_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.91049134
118LXR_22292898_ChIP-Seq_THP-1_Human0.90848561
119KDM2B_26808549_Chip-Seq_K562_Human0.90254696
120RACK7_27058665_Chip-Seq_MCF-7_Human0.89707453
121GATA2_21666600_ChIP-Seq_HMVEC_Human0.89604534

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0000569_abnormal_digit_pigmentation3.75919246
2MP0003303_peritoneal_inflammation3.48915591
3MP0003300_gastrointestinal_ulcer3.10076902
4MP0003705_abnormal_hypodermis_morpholog2.95257277
5MP0010352_gastrointestinal_tract_polyps2.78259400
6MP0005076_abnormal_cell_differentiation2.64198571
7MP0003172_abnormal_lysosome_physiology2.62624807
8MP0003724_increased_susceptibility_to2.56941746
9MP0010307_abnormal_tumor_latency2.51939639
10MP0005058_abnormal_lysosome_morphology2.47615160
11MP0005451_abnormal_body_composition2.37173263
12MP0001835_abnormal_antigen_presentation2.35088114
13MP0003436_decreased_susceptibility_to2.34113970
14MP0009840_abnormal_foam_cell2.04070227
15MP0004947_skin_inflammation2.03533632
16MP0004510_myositis1.96342269
17MP0009278_abnormal_bone_marrow1.93717938
18MP0002009_preneoplasia1.92315338
19MP0003566_abnormal_cell_adhesion1.91214930
20MP0008260_abnormal_autophagy1.87397323
21MP0001800_abnormal_humoral_immune1.86488113
22MP0002166_altered_tumor_susceptibility1.86335814
23MP0005464_abnormal_platelet_physiology1.83348528
24MP0003828_pulmonary_edema1.80222837
25MP0005387_immune_system_phenotype1.77202452
26MP0001790_abnormal_immune_system1.77202452
27MP0002419_abnormal_innate_immunity1.72680527
28MP0002452_abnormal_antigen_presenting1.69862435
29MP0000685_abnormal_immune_system1.68681982
30MP0005000_abnormal_immune_tolerance1.63880734
31MP0004808_abnormal_hematopoietic_stem1.61626234
32MP0006082_CNS_inflammation1.58293146
33MP0003091_abnormal_cell_migration1.56200184
34MP0004381_abnormal_hair_follicle1.52388322
35MP0002723_abnormal_immune_serum1.50225339
36MP0005360_urolithiasis1.47094010
37MP0003191_abnormal_cellular_cholesterol1.47037555
38MP0002006_tumorigenesis1.45084653
39MP0003252_abnormal_bile_duct1.44389551
40MP0008961_abnormal_basal_metabolism1.43504896
41MP0004185_abnormal_adipocyte_glucose1.42000692
42MP0002420_abnormal_adaptive_immunity1.38221792
43MP0001819_abnormal_immune_cell1.38039818
44MP0002398_abnormal_bone_marrow1.37287655
45MP0005025_abnormal_response_to1.36707828
46MP0003448_altered_tumor_morphology1.35977010
47MP0003045_fibrosis1.35877843
48MP0005023_abnormal_wound_healing1.35417455
49MP0000733_abnormal_muscle_development1.31245495
50MP0005409_darkened_coat_color1.30588868
51MP0008057_abnormal_DNA_replication1.28790604
52MP0010234_abnormal_vibrissa_follicle1.27852977
53MP0004264_abnormal_extraembryonic_tissu1.27794864
54MP0001545_abnormal_hematopoietic_system1.27063576
55MP0005397_hematopoietic_system_phenotyp1.27063576
56MP0005365_abnormal_bile_salt1.26758985
57MP0002396_abnormal_hematopoietic_system1.25158122
58MP0001851_eye_inflammation1.23185590
59MP0002139_abnormal_hepatobiliary_system1.22527895
60MP0001533_abnormal_skeleton_physiology1.22416782
61MP0002405_respiratory_system_inflammati1.22329506
62MP0000716_abnormal_immune_system1.21676007
63MP0000609_abnormal_liver_physiology1.21665600
64MP0000689_abnormal_spleen_morphology1.20830716
65MP0000371_diluted_coat_color1.20105314
66MP0005671_abnormal_response_to1.19830664
67MP0009785_altered_susceptibility_to1.17425305
68MP0001845_abnormal_inflammatory_respons1.17267877
69MP0004130_abnormal_muscle_cell1.16850089
70MP0003453_abnormal_keratinocyte_physiol1.16657532
71MP0003183_abnormal_peptide_metabolism1.16207887
72MP0002722_abnormal_immune_system1.16079434
73MP0010155_abnormal_intestine_physiology1.15774836
74MP0002877_abnormal_melanocyte_morpholog1.15261033
75MP0005083_abnormal_biliary_tract1.11363074
76MP0000604_amyloidosis1.07149903
77MP0010329_abnormal_lipoprotein_level1.03339892
78MP0001915_intracranial_hemorrhage1.03284690
79MP0000703_abnormal_thymus_morphology1.02731610
80MP0002429_abnormal_blood_cell1.02685707
81MP0001849_ear_inflammation1.00926638
82MP0001873_stomach_inflammation1.00788360
83MP0004883_abnormal_blood_vessel1.00748224
84MP0003866_abnormal_defecation1.00526389
85MP0002998_abnormal_bone_remodeling0.99859838
86MP0001853_heart_inflammation0.99518010
87MP0003221_abnormal_cardiomyocyte_apopto0.99283724
88MP0005666_abnormal_adipose_tissue0.96050265
89MP0002796_impaired_skin_barrier0.95988760
90MP0008469_abnormal_protein_level0.95547952
91MP0000858_altered_metastatic_potential0.95483198
92MP0000015_abnormal_ear_pigmentation0.91463292
93MP0000598_abnormal_liver_morphology0.91266990
94MP0004233_abnormal_muscle_weight0.90100825
95MP0002928_abnormal_bile_duct0.89245293
96MP0005257_abnormal_intraocular_pressure0.88316078
97MP0005174_abnormal_tail_pigmentation0.87522566
98MP0003763_abnormal_thymus_physiology0.86071103
99MP0002254_reproductive_system_inflammat0.84503493
100MP0003075_altered_response_to0.83622475
101MP0005164_abnormal_response_to0.83491000
102MP0000465_gastrointestinal_hemorrhage0.82581078
103MP0005310_abnormal_salivary_gland0.82079274
104MP0002086_abnormal_extraembryonic_tissu0.80103362
105MP0005166_decreased_susceptibility_to0.79884961
106MP0003690_abnormal_glial_cell0.79486758
107MP0005085_abnormal_gallbladder_physiolo0.77887062
108MP0005621_abnormal_cell_physiology0.76993123
109MP0001348_abnormal_lacrimal_gland0.76312830
110MP0009763_increased_sensitivity_to0.76307199
111MP0004197_abnormal_fetal_growth/weight/0.75249868
112MP0009333_abnormal_splenocyte_physiolog0.75059366
113MP0000490_abnormal_crypts_of0.73601335
114MP0002088_abnormal_embryonic_growth/wei0.73577040
115MP0009115_abnormal_fat_cell0.72999534
116MP0002148_abnormal_hypersensitivity_rea0.72963590
117MP0003656_abnormal_erythrocyte_physiolo0.72919073
118MP0000767_abnormal_smooth_muscle0.72598302
119MP0003984_embryonic_growth_retardation0.71740136
120MP0002933_joint_inflammation0.71595330
121MP0001216_abnormal_epidermal_layer0.71438325
122MP0003795_abnormal_bone_structure0.69932636

Predicted human phenotypes

RankGene SetZ-score
1Eczematoid dermatitis (HP:0000976)3.22444371
2Myocardial infarction (HP:0001658)3.06110519
3Increased cerebral lipofuscin (HP:0011813)2.99293208
4Orchitis (HP:0100796)2.93648177
5Cerebral aneurysm (HP:0004944)2.93315915
6Autoimmune thrombocytopenia (HP:0001973)2.85436479
7Gastrointestinal infarctions (HP:0005244)2.83901908
8Recurrent viral infections (HP:0004429)2.82217524
9Abnormality of the fingertips (HP:0001211)2.80865038
10Recurrent abscess formation (HP:0002722)2.79096990
11Recurrent gram-negative bacterial infections (HP:0005420)2.75463887
12Optic neuritis (HP:0100653)2.73099338
13Retrobulbar optic neuritis (HP:0100654)2.73099338
14Increased IgE level (HP:0003212)2.72640313
15Recurrent bacterial skin infections (HP:0005406)2.70349001
16Spontaneous hematomas (HP:0007420)2.63264912
17Hematochezia (HP:0002573)2.63087174
18Recurrent fungal infections (HP:0002841)2.61694966
19Vasculitis (HP:0002633)2.45382351
20Meningitis (HP:0001287)2.44947810
21Colitis (HP:0002583)2.44370659
22Macroorchidism (HP:0000053)2.40311754
23Pustule (HP:0200039)2.38219481
24Slow saccadic eye movements (HP:0000514)2.34474538
25Periodontitis (HP:0000704)2.33113182
26Increased neuronal autofluorescent lipopigment (HP:0002074)2.31401074
27Parkinsonism with favorable response to dopaminergic medication (HP:0002548)2.31254016
28Abnormality of mucopolysaccharide metabolism (HP:0011020)2.29701970
29Abnormality of polysaccharide metabolism (HP:0011012)2.29701970
30Abnormality of glycosaminoglycan metabolism (HP:0004371)2.29701970
31Broad face (HP:0000283)2.29454228
32Urinary glycosaminoglycan excretion (HP:0003541)2.29065691
33Mucopolysacchariduria (HP:0008155)2.29065691
34Hyperacusis (HP:0010780)2.27873344
35Subacute progressive viral hepatitis (HP:0006572)2.22182495
36Urethral obstruction (HP:0000796)2.19530524
37Heterotopia (HP:0002282)2.17266294
38Cellulitis (HP:0100658)2.17255120
39Frequent falls (HP:0002359)2.16076127
40Dysostosis multiplex (HP:0000943)2.15746901
41Prolonged bleeding time (HP:0003010)2.13783123
42Osteolytic defects of the hand bones (HP:0009699)2.13082243
43Osteolytic defects of the phalanges of the hand (HP:0009771)2.13082243
44Obstructive lung disease (HP:0006536)2.12974831
45Chronic obstructive pulmonary disease (HP:0006510)2.12974831
46Increased density of long bones (HP:0006392)2.12656529
47Gingival bleeding (HP:0000225)2.11373982
48Epistaxis (HP:0000421)2.09736146
49Thin bony cortex (HP:0002753)2.08658895
50Disinhibition (HP:0000734)2.07573102
51Flat acetabular roof (HP:0003180)2.07517841
52Arterial thrombosis (HP:0004420)2.04798364
53Systemic lupus erythematosus (HP:0002725)2.04570845
54Aortic aneurysm (HP:0004942)2.02767295
55Fatigue (HP:0012378)2.01780425
56Recurrent skin infections (HP:0001581)2.01705148
57Recurrent cutaneous fungal infections (HP:0011370)2.00175067
58Chronic mucocutaneous candidiasis (HP:0002728)2.00175067
59Mitral valve prolapse (HP:0001634)1.99745778
60Inflammation of the large intestine (HP:0002037)1.99572283
61Upper motor neuron abnormality (HP:0002127)1.98163673
62Gastrointestinal inflammation (HP:0004386)1.96564451
63Global brain atrophy (HP:0002283)1.96302627
64Cervical subluxation (HP:0003308)1.95401004
65Urticaria (HP:0001025)1.95361021
66Loss of speech (HP:0002371)1.95091740
67Absent frontal sinuses (HP:0002688)1.94465078
68Mediastinal lymphadenopathy (HP:0100721)1.93404481
69Interstitial pulmonary disease (HP:0006530)1.93350122
70Keratoconjunctivitis sicca (HP:0001097)1.93079158
71Viral hepatitis (HP:0006562)1.91215061
72Gingivitis (HP:0000230)1.90189676
73Obstructive sleep apnea (HP:0002870)1.90054933
74Abnormal delayed hypersensitivity skin test (HP:0002963)1.89873682
75Axonal loss (HP:0003447)1.89857145
76Abnormality of the thoracic spine (HP:0100711)1.89595371
77Complement deficiency (HP:0004431)1.89444430
78Dislocated radial head (HP:0003083)1.89234205
79Pulmonary infiltrates (HP:0002113)1.88861689
80Abnormal platelet function (HP:0011869)1.88040412
81Impaired platelet aggregation (HP:0003540)1.88040412
82Hemoptysis (HP:0002105)1.87793673
83Abnormality of macrophages (HP:0004311)1.87643724
84Spastic diplegia (HP:0001264)1.86417749
85Aneurysm (HP:0002617)1.85097672
86Upper limb amyotrophy (HP:0009129)1.84949320
87Distal upper limb amyotrophy (HP:0007149)1.84949320
88Ulnar bowing (HP:0003031)1.83514863
89Encephalitis (HP:0002383)1.82620277
90Spinal cord lesions (HP:0100561)1.82368268
91Syringomyelia (HP:0003396)1.82368268
92Increased CSF protein (HP:0002922)1.82332822
93Hand muscle atrophy (HP:0009130)1.82096187
94Esophageal varix (HP:0002040)1.80742276
95Abnormal platelet volume (HP:0011876)1.79955784
96Gastrointestinal stroma tumor (HP:0100723)1.79331214
97Deep venous thrombosis (HP:0002625)1.78649733
98Thoracic kyphosis (HP:0002942)1.78480662
99Persistence of primary teeth (HP:0006335)1.77287633
100Abnormality of T cells (HP:0002843)1.77264100
101Stomatitis (HP:0010280)1.77116847
102Segmental peripheral demyelination/remyelination (HP:0003481)1.76804992
103Cortical dysplasia (HP:0002539)1.76449150
104Osteomyelitis (HP:0002754)1.76359215
105Pseudobulbar signs (HP:0002200)1.76207138
106T lymphocytopenia (HP:0005403)1.76164393
107Increased mean platelet volume (HP:0011877)1.75735689
108Striae distensae (HP:0001065)1.75389798
109Sparse lateral eyebrow (HP:0005338)1.75128164
110Tetraparesis (HP:0002273)1.73639050
111Neonatal hypoglycemia (HP:0001998)1.72952073
112Coarse hair (HP:0002208)1.72866065
113Chronic otitis media (HP:0000389)1.72527037
114Narrow palate (HP:0000189)1.72183027
115Amyloidosis (HP:0011034)1.71900696
116Dilatation of the ascending aorta (HP:0005111)1.70462101
117Spondylolisthesis (HP:0003302)1.70276080
118Intracellular accumulation of autofluorescent lipopigment storage material (HP:0003204)1.69562109
119Joint hemorrhage (HP:0005261)1.68676604
120Abnormality of glycolipid metabolism (HP:0010969)1.68131359
121Abnormality of liposaccharide metabolism (HP:0010968)1.68131359
122Abnormality of glycosphingolipid metabolism (HP:0004343)1.68131359
123Lymphopenia (HP:0001888)1.68002790
124Volvulus (HP:0002580)1.67770335
125Distal lower limb amyotrophy (HP:0008944)1.67770033
126Dysmetric saccades (HP:0000641)1.67658580
127Abnormality of the radial head (HP:0003995)1.67549926
128Personality changes (HP:0000751)1.67181660
129Myositis (HP:0100614)1.67074881
130Leukocytosis (HP:0001974)1.66410194
131Abnormality of T cell number (HP:0011839)1.65554200
132Cutaneous melanoma (HP:0012056)1.65380781
133Vertebral compression fractures (HP:0002953)1.64983849
134Keratoconjunctivitis (HP:0001096)1.64977764
135Abnormality of the common coagulation pathway (HP:0010990)1.64919905
136Papilloma (HP:0012740)1.64465276
137Verrucae (HP:0200043)1.64465276
138Elfin facies (HP:0004428)1.64366464
139Cheilitis (HP:0100825)1.63905504
140Skin ulcer (HP:0200042)1.63664393
141Chest pain (HP:0100749)1.62905840
142Vacuolated lymphocytes (HP:0001922)1.62689702
143Mitral stenosis (HP:0001718)1.62000492
144Transitional cell carcinoma of the bladder (HP:0006740)1.61836958
145Prominent nose (HP:0000448)1.61308036
146Elevated erythrocyte sedimentation rate (HP:0003565)1.60452488

Predicted kinase interactions (KEA)

RankGene SetZ-score
1PRPF4B3.96082543
2CDK123.59526071
3TRIB32.89885810
4ERN12.57421237
5PKN22.55045521
6MAP3K102.45011967
7CAMK1D2.33149473
8MAP4K12.32852843
9EEF2K2.32773254
10TYK22.14756115
11TTN2.08599922
12SMG12.06173800
13SIK11.98133810
14LATS11.93881763
15RIPK11.93461598
16JAK11.87134419
17CAMK1G1.86219976
18TAOK31.81414754
19STK101.81155051
20IRAK41.76902490
21FGFR41.74645105
22PTK61.73300200
23TBK11.57660044
24FGFR31.56060827
25MAP3K141.53735237
26JAK31.50356740
27TGFBR21.44204931
28BRD41.40121057
29SCYL21.38042691
30SIK21.37150817
31ALK1.30466895
32CDK61.29706410
33BMX1.26788364
34HCK1.24048698
35TAOK21.24017864
36SIK31.21857039
37GRK61.18494874
38MAP3K11.17404048
39CSF1R1.17309968
40EPHB11.14520666
41LRRK21.14113145
42* MTOR1.13322684
43JAK21.12390855
44STK31.12280151
45ICK1.11773742
46CHUK1.10307200
47ZAP701.09933229
48RPS6KA41.09617659
49RIPK41.08705944
50MARK21.07713136
51IKBKE1.06610612
52MAP2K31.06575530
53PDGFRB1.05948015
54CDC42BPA1.05235266
55MAP3K131.03437592
56KIT1.01985368
57TXK1.00979323
58IRAK21.00118225
59ITK0.97407376
60NEK20.96565770
61IKBKB0.96180024
62PDGFRA0.94751908
63PIM10.93603221
64YES10.91476193
65SGK30.90915894
66TAOK10.90560214
67MAP3K70.89468175
68TRPM70.88013968
69DMPK0.86875095
70BMPR20.86768715
71CSK0.86203524
72CDK40.83892965
73FGR0.80716622
74TNK20.80522541
75PRKD20.80429909
76NEK90.79736934
77MARK30.79003814
78IRAK10.78281411
79EPHA30.76537583
80RET0.75295761
81SYK0.72130385
82IRAK30.69036700
83EGFR0.68490028
84BTK0.68280133
85MAP3K110.67632594
86MAP3K80.67003450
87STK40.66740844
88MAPK120.66154353
89LCK0.64498796
90PRKCH0.64477455
91MAP3K60.63590242
92RPS6KC10.63449590
93RPS6KL10.63449590
94FLT30.61904682
95PDK10.60830998
96RPS6KA20.58682165
97CDK90.57941137
98FRK0.55707603
99KSR20.55695498
100SGK20.55381526
101PAK20.55053027
102NLK0.54783105
103MAP3K20.54707585
104AKT30.53181034
105PTK20.52964278
106TEC0.52160013
107MAPK110.49982273
108MATK0.49310852
109WNK10.49268563
110RPS6KA60.48217078
111MELK0.48127036
112NME20.47013003
113PAK40.46005924
114ABL10.44723750
115MAP3K90.44367091
116BLK0.43435043
117PRKAA20.43078916
118CAMKK10.42495010
119HIPK20.41026421
120MAPK70.39586009
121PDPK10.38157238
122FES0.37787799
123MAP3K30.36433529
124MAP3K50.35884892
125INSR0.33276933
126DYRK1B0.32964159
127ERBB20.32777078
128ERBB40.32688022
129ATR0.32450186
130LYN0.31334655
131FGFR20.30304406

Predicted pathways (KEGG)

RankGene SetZ-score
1Nitrogen metabolism_Homo sapiens_hsa009102.20437085
2Osteoclast differentiation_Homo sapiens_hsa043801.98241670
3Staphylococcus aureus infection_Homo sapiens_hsa051501.96596590
4B cell receptor signaling pathway_Homo sapiens_hsa046621.95654516
5Leishmaniasis_Homo sapiens_hsa051401.95086282
6Chronic myeloid leukemia_Homo sapiens_hsa052201.78624420
7NF-kappa B signaling pathway_Homo sapiens_hsa040641.66674465
8Toll-like receptor signaling pathway_Homo sapiens_hsa046201.58570340
9Glycosaminoglycan degradation_Homo sapiens_hsa005311.57321589
10Lysine degradation_Homo sapiens_hsa003101.55306322
11mTOR signaling pathway_Homo sapiens_hsa041501.49069019
12Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046661.43054113
13Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004001.42971005
14Toxoplasmosis_Homo sapiens_hsa051451.42288479
15Insulin resistance_Homo sapiens_hsa049311.35278568
16Tuberculosis_Homo sapiens_hsa051521.32108372
17Fc epsilon RI signaling pathway_Homo sapiens_hsa046641.31546866
18Type II diabetes mellitus_Homo sapiens_hsa049301.30729670
19Acute myeloid leukemia_Homo sapiens_hsa052211.29034239
20TNF signaling pathway_Homo sapiens_hsa046681.28505351
21Caffeine metabolism_Homo sapiens_hsa002321.26703007
22Measles_Homo sapiens_hsa051621.26550390
23Allograft rejection_Homo sapiens_hsa053301.26351863
24Antigen processing and presentation_Homo sapiens_hsa046121.24873712
25Graft-versus-host disease_Homo sapiens_hsa053321.23978111
26Lysosome_Homo sapiens_hsa041421.22305638
27T cell receptor signaling pathway_Homo sapiens_hsa046601.20984253
28NOD-like receptor signaling pathway_Homo sapiens_hsa046211.20690416
29Neurotrophin signaling pathway_Homo sapiens_hsa047221.20123149
30Non-small cell lung cancer_Homo sapiens_hsa052231.19017550
31Arginine biosynthesis_Homo sapiens_hsa002201.18412071
32Pancreatic cancer_Homo sapiens_hsa052121.17201624
33Apoptosis_Homo sapiens_hsa042101.15318359
34Influenza A_Homo sapiens_hsa051641.14707050
35Autoimmune thyroid disease_Homo sapiens_hsa053201.13310719
36Bacterial invasion of epithelial cells_Homo sapiens_hsa051001.13299775
37Small cell lung cancer_Homo sapiens_hsa052221.12883476
38Complement and coagulation cascades_Homo sapiens_hsa046101.12166377
39Hepatitis B_Homo sapiens_hsa051611.11749048
40Adipocytokine signaling pathway_Homo sapiens_hsa049201.11198299
41MicroRNAs in cancer_Homo sapiens_hsa052061.10226922
42Dorso-ventral axis formation_Homo sapiens_hsa043201.06235225
43Proteoglycans in cancer_Homo sapiens_hsa052051.05055863
44Chagas disease (American trypanosomiasis)_Homo sapiens_hsa051421.03881190
45Thyroid cancer_Homo sapiens_hsa052161.01959769
46Bladder cancer_Homo sapiens_hsa052191.01917104
47Leukocyte transendothelial migration_Homo sapiens_hsa046701.01630646
48Legionellosis_Homo sapiens_hsa051341.01134422
49Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046501.00056281
50AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049330.99598887
51Primary immunodeficiency_Homo sapiens_hsa053400.97443947
52Butirosin and neomycin biosynthesis_Homo sapiens_hsa005240.96774934
53Jak-STAT signaling pathway_Homo sapiens_hsa046300.96629385
54Pertussis_Homo sapiens_hsa051330.96433340
55Glioma_Homo sapiens_hsa052140.95691186
56Prolactin signaling pathway_Homo sapiens_hsa049170.94976187
57RIG-I-like receptor signaling pathway_Homo sapiens_hsa046220.94768839
58Malaria_Homo sapiens_hsa051440.94257755
59Endometrial cancer_Homo sapiens_hsa052130.92132391
60Sphingolipid signaling pathway_Homo sapiens_hsa040710.90885576
61Hepatitis C_Homo sapiens_hsa051600.90265903
62Carbohydrate digestion and absorption_Homo sapiens_hsa049730.90203007
63Chemokine signaling pathway_Homo sapiens_hsa040620.90072758
64Amoebiasis_Homo sapiens_hsa051460.89145242
65Primary bile acid biosynthesis_Homo sapiens_hsa001200.88153601
66Viral myocarditis_Homo sapiens_hsa054160.88081967
67Herpes simplex infection_Homo sapiens_hsa051680.87261497
68GnRH signaling pathway_Homo sapiens_hsa049120.86774471
69FoxO signaling pathway_Homo sapiens_hsa040680.85353368
70Platelet activation_Homo sapiens_hsa046110.84754415
71Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.83950081
72Selenocompound metabolism_Homo sapiens_hsa004500.83572627
73Viral carcinogenesis_Homo sapiens_hsa052030.82862922
74Choline metabolism in cancer_Homo sapiens_hsa052310.82535107
75Adherens junction_Homo sapiens_hsa045200.82508619
76Central carbon metabolism in cancer_Homo sapiens_hsa052300.81745866
77Phospholipase D signaling pathway_Homo sapiens_hsa040720.80089400
78Type I diabetes mellitus_Homo sapiens_hsa049400.79217348
79One carbon pool by folate_Homo sapiens_hsa006700.78083452
80Inflammatory bowel disease (IBD)_Homo sapiens_hsa053210.77956453
81Insulin signaling pathway_Homo sapiens_hsa049100.76711638
82Longevity regulating pathway - mammal_Homo sapiens_hsa042110.76032170
83Phagosome_Homo sapiens_hsa041450.75512660
84HIF-1 signaling pathway_Homo sapiens_hsa040660.74877900
85Thyroid hormone signaling pathway_Homo sapiens_hsa049190.74522609
86Epstein-Barr virus infection_Homo sapiens_hsa051690.74411942
87Renal cell carcinoma_Homo sapiens_hsa052110.74182918
88VEGF signaling pathway_Homo sapiens_hsa043700.73901525
89Shigellosis_Homo sapiens_hsa051310.73435648
90Phosphatidylinositol signaling system_Homo sapiens_hsa040700.72496358
91Prostate cancer_Homo sapiens_hsa052150.70718837
92Colorectal cancer_Homo sapiens_hsa052100.70227294
93Endocytosis_Homo sapiens_hsa041440.70118172
94Focal adhesion_Homo sapiens_hsa045100.70062576
95Hematopoietic cell lineage_Homo sapiens_hsa046400.69403209
96Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.67284205
97Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.66019314
98African trypanosomiasis_Homo sapiens_hsa051430.66014489
99HTLV-I infection_Homo sapiens_hsa051660.65531728
100Transcriptional misregulation in cancer_Homo sapiens_hsa052020.64844260
101Intestinal immune network for IgA production_Homo sapiens_hsa046720.64300187
102AMPK signaling pathway_Homo sapiens_hsa041520.63255171
103Estrogen signaling pathway_Homo sapiens_hsa049150.62826931
104ABC transporters_Homo sapiens_hsa020100.62142879
105Salmonella infection_Homo sapiens_hsa051320.62095785
106Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049600.61727107
107MAPK signaling pathway_Homo sapiens_hsa040100.60975340
108PPAR signaling pathway_Homo sapiens_hsa033200.60153770
109Ascorbate and aldarate metabolism_Homo sapiens_hsa000530.60042898
110Asthma_Homo sapiens_hsa053100.59942233
111Inositol phosphate metabolism_Homo sapiens_hsa005620.59467611
112Regulation of actin cytoskeleton_Homo sapiens_hsa048100.59339302
113Notch signaling pathway_Homo sapiens_hsa043300.57657789
114Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.56705688
115Other glycan degradation_Homo sapiens_hsa005110.54873060
116Rheumatoid arthritis_Homo sapiens_hsa053230.54713629
117Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005320.54472187
118Bile secretion_Homo sapiens_hsa049760.51502399
119ErbB signaling pathway_Homo sapiens_hsa040120.48429633

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