SLC5A9

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1very-low-density lipoprotein particle assembly (GO:0034379)7.68002818
2plasma lipoprotein particle assembly (GO:0034377)7.30801705
3desmosome organization (GO:0002934)6.63264625
4protein-lipid complex assembly (GO:0065005)6.53382903
5regulation of water loss via skin (GO:0033561)6.24026027
6establishment of skin barrier (GO:0061436)6.21010841
7epoxygenase P450 pathway (GO:0019373)6.15488991
8regulation of cholesterol esterification (GO:0010872)6.09362570
9regulation of bile acid biosynthetic process (GO:0070857)6.01172952
10bundle of His cell to Purkinje myocyte communication (GO:0086069)5.81130817
11fat-soluble vitamin biosynthetic process (GO:0042362)5.79919815
12lipoprotein transport (GO:0042953)5.75624840
13hemidesmosome assembly (GO:0031581)5.65869488
14plasma lipoprotein particle remodeling (GO:0034369)5.44425419
15protein-lipid complex remodeling (GO:0034368)5.44425419
16macromolecular complex remodeling (GO:0034367)5.44425419
17high-density lipoprotein particle remodeling (GO:0034375)5.43713943
18cholesterol efflux (GO:0033344)5.31515940
19diacylglycerol metabolic process (GO:0046339)5.31447841
20plasma lipoprotein particle organization (GO:0071827)5.23784804
21triglyceride-rich lipoprotein particle remodeling (GO:0034370)5.03980000
22NADH metabolic process (GO:0006734)5.02042883
23low-density lipoprotein particle remodeling (GO:0034374)4.96116607
24protein-lipid complex subunit organization (GO:0071825)4.94102846
25negative regulation of fibrinolysis (GO:0051918)4.92403437
26reverse cholesterol transport (GO:0043691)4.89954767
27multicellular organismal water homeostasis (GO:0050891)4.87141897
28fructose metabolic process (GO:0006000)4.77049738
29regulation of triglyceride catabolic process (GO:0010896)4.75818241
30lipoprotein metabolic process (GO:0042157)4.72907279
31positive regulation of lipoprotein lipase activity (GO:0051006)4.59398144
32positive regulation of triglyceride lipase activity (GO:0061365)4.59398144
33keratinization (GO:0031424)4.50845564
34regulation of guanylate cyclase activity (GO:0031282)4.45965911
35renal absorption (GO:0070293)4.45059960
36drug transmembrane transport (GO:0006855)4.43441996
37peptide catabolic process (GO:0043171)4.43271851
38regulation of protein activation cascade (GO:2000257)4.43247345
39drug metabolic process (GO:0017144)4.41779852
40regulation of systemic arterial blood pressure mediated by a chemical signal (GO:0003044)4.40020832
41endocrine process (GO:0050886)4.40020832
42regulation of systemic arterial blood pressure by hormone (GO:0001990)4.40020832
43regulation of fibrinolysis (GO:0051917)4.39392897
44angiotensin maturation (GO:0002003)4.36494549
45regulation of complement activation (GO:0030449)4.32180665
46intestinal absorption (GO:0050892)4.32057460
47regulation of cholesterol homeostasis (GO:2000188)4.25791837
48phospholipid scrambling (GO:0017121)4.25546548
49detection of bacterium (GO:0016045)4.16514057
50excretion (GO:0007588)4.10381989
51protein carboxylation (GO:0018214)4.10196708
52peptidyl-glutamic acid carboxylation (GO:0017187)4.10196708
53negative regulation of cholesterol transport (GO:0032375)4.09880757
54negative regulation of sterol transport (GO:0032372)4.09880757
55surfactant homeostasis (GO:0043129)4.07808796
56one-carbon compound transport (GO:0019755)4.06790896
57urea metabolic process (GO:0019627)4.06776513
58cellular glucuronidation (GO:0052695)4.05127562
59cholesterol homeostasis (GO:0042632)4.05120037
60drug transport (GO:0015893)4.02589026
61proline metabolic process (GO:0006560)4.00585175
62sterol homeostasis (GO:0055092)3.99003707
63water homeostasis (GO:0030104)3.98673859
64urea cycle (GO:0000050)3.98436190
65virion attachment to host cell (GO:0019062)3.95773472
66adhesion of symbiont to host cell (GO:0044650)3.95773472
67glucuronate metabolic process (GO:0019585)3.94320601
68uronic acid metabolic process (GO:0006063)3.94320601
69response to phenylpropanoid (GO:0080184)3.91195206
70fatty acid beta-oxidation using acyl-CoA oxidase (GO:0033540)3.87728090
71positive regulation of fatty acid biosynthetic process (GO:0045723)3.84174334
72renal system process involved in regulation of systemic arterial blood pressure (GO:0003071)3.82791536
73urate metabolic process (GO:0046415)3.77126542
74nonribosomal peptide biosynthetic process (GO:0019184)3.77040881
75vitamin transmembrane transport (GO:0035461)3.75937337
76regulation of systemic arterial blood pressure (GO:0003073)3.75927417
77bile acid and bile salt transport (GO:0015721)3.75067859
78keratinocyte differentiation (GO:0030216)3.72812322
79exogenous drug catabolic process (GO:0042738)3.72596914
80L-ascorbic acid metabolic process (GO:0019852)3.70101370
81sphingoid metabolic process (GO:0046519)3.69148894
82nitrogen cycle metabolic process (GO:0071941)3.68983551
83interferon-gamma secretion (GO:0072643)3.67176466
84bile acid metabolic process (GO:0008206)3.65707521
85hormone catabolic process (GO:0042447)3.65109920
86detection of other organism (GO:0098543)3.64728625
87chemical homeostasis within a tissue (GO:0048875)3.60523889
88glutathione biosynthetic process (GO:0006750)3.58831554
89polyol transport (GO:0015791)3.56539473
90plasma lipoprotein particle clearance (GO:0034381)3.53079120
91drinking behavior (GO:0042756)3.51255696
92regulation of apoptotic cell clearance (GO:2000425)3.50407520
93glutamine family amino acid biosynthetic process (GO:0009084)3.48746592
94transepithelial transport (GO:0070633)3.48660982
95positive regulation of lipid catabolic process (GO:0050996)3.46502845
96intermediate filament organization (GO:0045109)3.43112903
97antigen processing and presentation of endogenous antigen (GO:0019883)3.42405227
98drug catabolic process (GO:0042737)3.37107414
99regulation of ruffle assembly (GO:1900027)3.36988617
100complement activation, alternative pathway (GO:0006957)3.36297580
101regulation of natural killer cell differentiation (GO:0032823)3.32975250
102erythrose 4-phosphate/phosphoenolpyruvate family amino acid catabolic process (GO:1902222)3.31848473
103L-phenylalanine catabolic process (GO:0006559)3.31848473
104blood coagulation, intrinsic pathway (GO:0007597)3.31460255
105negative regulation of hemostasis (GO:1900047)3.29491295
106negative regulation of blood coagulation (GO:0030195)3.29491295
107diol metabolic process (GO:0034311)3.29388885
108intestinal cholesterol absorption (GO:0030299)3.29048157
109modified amino acid transport (GO:0072337)3.28886589
110acylglycerol homeostasis (GO:0055090)3.28565933
111triglyceride homeostasis (GO:0070328)3.28565933
112calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules (GO:0016338)3.26406241
113regulation of cholesterol metabolic process (GO:0090181)3.26340515
114beta-amyloid metabolic process (GO:0050435)3.26024077
115proline biosynthetic process (GO:0006561)3.23288773
116organic cation transport (GO:0015695)3.22859015
117sphingosine metabolic process (GO:0006670)3.21189751
118glutathione derivative metabolic process (GO:1901685)3.20810062
119glutathione derivative biosynthetic process (GO:1901687)3.20810062
120renal system process involved in regulation of blood volume (GO:0001977)3.20470472
121lysine metabolic process (GO:0006553)3.19694753
122lysine catabolic process (GO:0006554)3.19694753
123positive regulation of guanylate cyclase activity (GO:0031284)3.19398750
124ethanol metabolic process (GO:0006067)3.18835900
125L-phenylalanine metabolic process (GO:0006558)3.18322494
126erythrose 4-phosphate/phosphoenolpyruvate family amino acid metabolic process (GO:1902221)3.18322494
127phosphate ion transport (GO:0006817)3.17472344
128epidermal cell differentiation (GO:0009913)3.16918877
129maintenance of gastrointestinal epithelium (GO:0030277)3.14824599
130lipid homeostasis (GO:0055088)3.13871610
131cholesterol transport (GO:0030301)3.12683551
132sterol transport (GO:0015918)3.12683551
133hydrogen peroxide catabolic process (GO:0042744)3.11643217
134positive regulation of steroid metabolic process (GO:0045940)3.10380370
135peptide hormone processing (GO:0016486)3.10118252
136complement activation, classical pathway (GO:0006958)3.09773903
137antigen processing and presentation of endogenous peptide antigen via MHC class I (GO:0019885)3.08808576
138antigen processing and presentation of endogenous peptide antigen (GO:0002483)3.08808576
139regulation of transforming growth factor beta1 production (GO:0032908)3.08244714
140vitamin biosynthetic process (GO:0009110)3.06114569
141negative regulation of coagulation (GO:0050819)3.05923032
142adhesion of symbiont to host (GO:0044406)3.04315551
143intestinal epithelial cell development (GO:0060576)2.96761499
144keratinocyte proliferation (GO:0043616)2.94923023
145flavonoid metabolic process (GO:0009812)2.92533023
146peptide cross-linking (GO:0018149)2.92391194
147growth hormone receptor signaling pathway (GO:0060396)2.91215525
148innate immune response in mucosa (GO:0002227)2.90298778
149phosphate ion transmembrane transport (GO:0035435)2.84030277
150antibacterial humoral response (GO:0019731)2.82488432
151positive regulation of hair follicle development (GO:0051798)2.81341501
152positive regulation of hair cycle (GO:0042635)2.81341501
153cellular response to vitamin D (GO:0071305)2.81208320
154gas transport (GO:0015669)2.78918183
155tight junction assembly (GO:0070830)2.78195662
156peptide biosynthetic process (GO:0043043)2.77014982
157positive regulation of Cdc42 GTPase activity (GO:0043089)2.76433881
158thyroid hormone metabolic process (GO:0042403)2.75924394
159epithelial cell-cell adhesion (GO:0090136)2.75883539
160vitamin A metabolic process (GO:0006776)2.75754459
161positive regulation of epidermis development (GO:0045684)2.72257302
162regulation of systemic arterial blood pressure by renin-angiotensin (GO:0003081)2.70462098
163cysteine metabolic process (GO:0006534)2.69865162
164antimicrobial humoral response (GO:0019730)2.68468706
165negative regulation of keratinocyte proliferation (GO:0010839)2.68289338
166ethanol oxidation (GO:0006069)2.65080052
167ectoderm development (GO:0007398)2.64952487
168cytoskeletal anchoring at plasma membrane (GO:0007016)2.64523328
169epidermis development (GO:0008544)2.64334537
170toxin transport (GO:1901998)2.62871064
171organ or tissue specific immune response (GO:0002251)2.62628224
172epithelial cell differentiation involved in prostate gland development (GO:0060742)2.60965631
173positive regulation of interleukin-8 secretion (GO:2000484)2.60004524
174digestive system process (GO:0022600)2.59396210
175phosphate ion homeostasis (GO:0055062)2.58683813
176trivalent inorganic anion homeostasis (GO:0072506)2.58683813
177xenobiotic catabolic process (GO:0042178)2.58458964
178actin filament depolymerization (GO:0030042)2.58377645
179phospholipid efflux (GO:0033700)2.55572631
180aminoglycoside antibiotic metabolic process (GO:0030647)2.54182107
181O-glycan processing (GO:0016266)2.52862565
1823-phosphoadenosine 5-phosphosulfate metabolic process (GO:0050427)2.51287530
183purine ribonucleoside bisphosphate metabolic process (GO:0034035)2.51287530
184mucosal immune response (GO:0002385)2.50582233
185sulfur compound transport (GO:0072348)2.50553275

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse5.26399615
2ESR1_21235772_ChIP-Seq_MCF-7_Human3.28926344
3TRIM28_21343339_ChIP-Seq_HEK293_Human3.27924081
4ESR2_21235772_ChIP-Seq_MCF-7_Human2.99600243
5SMAD4_19686287_ChIP-ChIP_HaCaT_Human2.65977690
6CDX2_20551321_ChIP-Seq_CACO-2_Human2.61890846
7SOX2_27498859_Chip-Seq_STOMACH_Mouse2.59672085
8* HNF4A_19822575_ChIP-Seq_HepG2_Human2.50056949
9THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse2.27275925
10STAT5_23275557_ChIP-Seq_MAMMARY-EPITHELIUM_Mouse2.26384354
11SOX2_20726797_ChIP-Seq_SW620_Human2.21799058
12FOXO3_23340844_ChIP-Seq_DLD1_Human2.19681735
13GATA4_25053715_ChIP-Seq_YYC3_Human2.18684797
14SOX9_24532713_ChIP-Seq_HFSC_Mouse2.11520281
15P63_26484246_Chip-Seq_KERATINOCYTES_Human2.04391072
16ZNF263_19887448_ChIP-Seq_K562_Human2.00500814
17TP63_17297297_ChIP-ChIP_HaCaT_Human10.3345067
18RARG_19884340_ChIP-ChIP_MEFs_Mouse1.99929978
19CEBPA_23403033_ChIP-Seq_LIVER_Mouse1.93073598
20ZNF217_24962896_ChIP-Seq_MCF-7_Human1.90051769
21GATA6_25053715_ChIP-Seq_YYC3_Human1.89765575
22RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human1.83962781
23RUNX1_27514584_Chip-Seq_MCF-7_Human1.83501529
24PPARA_22158963_ChIP-Seq_LIVER_Mouse1.77326059
25PPAR_26484153_Chip-Seq_NCI-H1993_Human1.77048501
26KLF6_26769127_Chip-Seq_PDAC-Cell_line_Human1.74768241
27PPARG_19300518_ChIP-PET_3T3-L1_Mouse1.72266414
28TFAP2C_20629094_ChIP-Seq_MCF-7_Human1.70808803
29SMAD2_18955504_ChIP-ChIP_HaCaT_Human1.69547699
30SMAD3_18955504_ChIP-ChIP_HaCaT_Human1.69547699
31FOXA1_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human1.68349396
32ESR1_17901129_ChIP-ChIP_LIVER_Mouse1.67592612
33RACK7_27058665_Chip-Seq_MCF-7_Human1.67018031
34RXR_22158963_ChIP-Seq_LIVER_Mouse1.66163029
35LXR_22158963_ChIP-Seq_LIVER_Mouse1.65439692
36TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat1.64373482
37ESR1_20079471_ChIP-ChIP_T-47D_Human1.60579075
38CLOCK_20551151_ChIP-Seq_293T_Human1.54840868
39ERA_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human1.53526037
40TCF7L2_21901280_ChIP-Seq_H4IIE_Rat1.53162631
41KLF4_26769127_Chip-Seq_PDAC-Cell_line_Human1.53061204
42TCF4_18268006_ChIP-ChIP_LS174T_Human1.50720042
43KLF5_25053715_ChIP-Seq_YYC3_Human1.48717378
44* MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human1.47124633
45ELF3_26769127_Chip-Seq_PDAC-Cell_line_Human1.46769825
46HIF1A_21447827_ChIP-Seq_MCF-7_Human1.42767381
47NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse1.42115143
48PBX_27287812_Chip-Seq_EMBYONIC-LIMB_Mouse1.40400143
49FOXA1_26769127_Chip-Seq_PDAC-Cell_line_Human1.39496494
50GATA3_24758297_ChIP-Seq_MCF-7_Human1.35573122
51HNF4A_19761587_ChIP-ChIP_CACO-2_Human1.33941152
52IRF1_21803131_ChIP-Seq_MONOCYTES_Human1.32270460
53BP1_19119308_ChIP-ChIP_Hs578T_Human1.25977706
54ATF3_27146783_Chip-Seq_COLON_Human1.23066265
55FOXA1_21915096_ChIP-Seq_LNCaP-1F5_Human1.22991872
56TP63_23658742_ChIP-Seq_EP156T_Human1.21482780
57AHR_22903824_ChIP-Seq_MCF-7_Human1.20699327
58GATA1_22025678_ChIP-Seq_K562_Human1.20225999
59SALL4_18804426_ChIP-ChIP_XEN_Mouse1.19968019
60CJUN_26792858_Chip-Seq_BT549_Human1.19129713
61CEBPB_23403033_ChIP-Seq_LIVER_Mouse1.13632301
62NR1I2_20693526_ChIP-Seq_LIVER_Mouse1.13389561
63TCF21_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human1.10837330
64* LXR_22292898_ChIP-Seq_THP-1_Human1.09130371
65STAT6_21828071_ChIP-Seq_BEAS2B_Human1.08955221
66SMARCA4_20176728_ChIP-ChIP_TSCs_Mouse1.07965472
67NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human1.07235304
68CDX2_19796622_ChIP-Seq_MESCs_Mouse1.05458007
69FOXM1_26456572_ChIP-Seq_MCF-7_Human1.03122703
70AR_21915096_ChIP-Seq_LNCaP-1F5_Human1.03067892
71BMI1_19503595_ChIP-Seq_MEFsC_Mouse1.00797379
72BACH1_22875853_ChIP-PCR_HELA_AND_SCP4_Human1.00436034
73TAF7L_23326641_ChIP-Seq_C3H10T1-2_Mouse0.99509677
74ARNT_22903824_ChIP-Seq_MCF-7_Human0.98656175
75PPARD_23176727_ChIP-Seq_KERATINOCYTES_Mouse0.97081059
76TP63_22573176_ChIP-Seq_HFKS_Human0.96749414
77STAT6_20620947_ChIP-Seq_CD4_POS_T_Human0.96663818
78CHD7_19251738_ChIP-ChIP_MESCs_Mouse0.94901340
79TP53_18474530_ChIP-ChIP_U2OS_Human0.94267922
80GATA2_19941826_ChIP-Seq_K562_Human0.92480272
81CEBPB_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse0.91640102
82* SRY_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse0.90787567
83DNAJC2_21179169_ChIP-ChIP_NT2_Human0.90613059
84JARID1B-DAIN_22020125_ChIP-Seq_ESCs_Mouse0.90206811
85FOXA1_25552417_ChIP-Seq_VCAP_Human0.89766920
86BCOR_27268052_Chip-Seq_Bcells_Human0.89394040
87FOXA2_19822575_ChIP-Seq_HepG2_Human0.89152916
88SOX9_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse0.89016420
89JUND_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human0.87208974
90EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse0.86047756
91GATA2_21666600_ChIP-Seq_HMVEC_Human0.85814234
92CTNNB1_20460455_ChIP-Seq_HCT116_Human0.85760621
93TBX20_22080862_ChIP-Seq_HEART_Mouse0.84957252
94TBX20_22328084_ChIP-Seq_HEART_Mouse0.84957252
95GATA3_20176728_ChIP-ChIP_TSCs_Mouse0.84567356
96NFIB_24661679_ChIP-Seq_LUNG_Mouse0.84422876
97Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse0.83449945
98GLI1_17442700_ChIP-ChIP_MESCs_Mouse0.82780766
99CTCF_27219007_Chip-Seq_Bcells_Human0.81342270
100KAP1_22055183_ChIP-Seq_ESCs_Mouse0.81269219
101BCL6_27268052_Chip-Seq_Bcells_Human0.80306616
102STAT3_20064451_ChIP-Seq_CD4+T_Mouse0.79918527
103RAD21_21589869_ChIP-Seq_MESCs_Mouse0.79019596
104RARA_24833708_ChIP-Seq_LIVER_Mouse0.78757580
105CTNNB1_24651522_ChIP-Seq_LGR5+_INTESTINAL_STEM_Human0.78597314
106SMAD3_22036565_ChIP-Seq_ESCs_Mouse0.78254387
107GATA1_19941826_ChIP-Seq_K562_Human0.78089551
108SMAD2/3_21741376_ChIP-Seq_ESCs_Human0.78043319
109SA1_27219007_Chip-Seq_Bcells_Human0.77832968
110SREBP2_21459322_ChIP-Seq_LIVER_Mouse0.77607855
111PPARD_23208498_ChIP-Seq_MDA-MB-231_Human0.76669515
112RXR_22108803_ChIP-Seq_LS180_Human0.76573090
113PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse0.75440094
114ETS2_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse0.75270309
115GATA1_19941827_ChIP-Seq_MEL_Mouse0.74707834
116* UBF1/2_26484160_Chip-Seq_HMECs_Human0.74216840
117TET1_21451524_ChIP-Seq_MESCs_Mouse0.73198095
118PIAS1_25552417_ChIP-Seq_VCAP_Human0.72993534
119JUN_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human0.72854192
120AR_21909140_ChIP-Seq_LNCAP_Human0.72668374
121NR0B1_18358816_ChIP-ChIP_MESCs_Mouse0.70817701
122P300_27058665_Chip-Seq_ZR-75-30cells_Human0.70289330
123NANOG_20526341_ChIP-Seq_ESCs_Human0.68975570
124CREB1_26743006_Chip-Seq_LNCaP-abl_Human0.68448965
125SOX9_22984422_ChIP-ChIP_TESTIS_Rat0.67987563
126DROSHA_22980978_ChIP-Seq_HELA_Human0.67601557
127PBX1_22567123_ChIP-ChIP_OVCAR3_Human0.67588567
128EBNA1_20929547_Chip-Seq_RAJI-cells_Human0.67547502
129SMAD3_21741376_ChIP-Seq_HESCs_Human0.67369123
130CREB1_26743006_Chip-Seq_LNCaP_Human0.66315926
131TCF7_22412390_ChIP-Seq_EML_Mouse0.65015700
132CEBPB_22108803_ChIP-Seq_LS180_Human0.64505019
133FOXP3_17237761_ChIP-ChIP_TREG_Mouse0.64282586
134CDX2_22108803_ChIP-Seq_LS180_Human0.63823638
135ZIC3_20872845_ChIP-ChIP_MESCs_Mouse0.63642995
136EGR1_19032775_ChIP-ChIP_M12_Human0.63145692
137ESR1_15608294_ChIP-ChIP_MCF-7_Human0.63094862
138FOXO1_23066095_ChIP-Seq_LIVER_Mouse0.62967851
139TCF4_22108803_ChIP-Seq_LS180_Human0.62704562
140IRF8_22096565_ChIP-ChIP_GC-B_Human0.62442779
141EGR1_23403033_ChIP-Seq_LIVER_Mouse0.62327753
142BCAT_22108803_ChIP-Seq_LS180_Human0.61334652

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0010234_abnormal_vibrissa_follicle6.52538858
2MP0002254_reproductive_system_inflammat5.13662511
3MP0002796_impaired_skin_barrier4.83485880
4MP0005360_urolithiasis4.32535803
5MP0009840_abnormal_foam_cell3.95260758
6MP0004264_abnormal_extraembryonic_tissu3.05746599
7MP0005501_abnormal_skin_physiology2.98813605
8MP0003941_abnormal_skin_development2.89584828
9MP0010678_abnormal_skin_adnexa2.85835503
10MP0004019_abnormal_vitamin_homeostasis2.66097319
11MP0005451_abnormal_body_composition2.54770702
12MP0002098_abnormal_vibrissa_morphology2.51100880
13MP0003868_abnormal_feces_composition2.47287027
14MP0004381_abnormal_hair_follicle2.38949590
15MP0000579_abnormal_nail_morphology2.27587051
16MP0004043_abnormal_pH_regulation2.24154319
17MP0001666_abnormal_nutrient_absorption2.24139232
18MP0003453_abnormal_keratinocyte_physiol2.20204041
19MP0001216_abnormal_epidermal_layer2.15390838
20MP0004947_skin_inflammation2.15029116
21MP0005409_darkened_coat_color2.14299544
22MP0000383_abnormal_hair_follicle2.11592811
23MP0005275_abnormal_skin_tensile2.09395814
24MP0002060_abnormal_skin_morphology2.02240217
25MP0001346_abnormal_lacrimal_gland1.94042984
26MP0008875_abnormal_xenobiotic_pharmacok1.89249215
27MP0003300_gastrointestinal_ulcer1.87977439
28MP0009643_abnormal_urine_homeostasis1.80076045
29MP0000538_abnormal_urinary_bladder1.78299264
30MP0010771_integument_phenotype1.77010717
31MP0005670_abnormal_white_adipose1.73570583
32MP0001765_abnormal_ion_homeostasis1.72923604
33MP0000377_abnormal_hair_follicle1.72157301
34MP0002118_abnormal_lipid_homeostasis1.70829632
35MP0003191_abnormal_cellular_cholesterol1.61402886
36MP0000609_abnormal_liver_physiology1.60274172
37MP0001849_ear_inflammation1.60055094
38MP0002876_abnormal_thyroid_physiology1.58782094
39MP0002139_abnormal_hepatobiliary_system1.55442661
40MP0005377_hearing/vestibular/ear_phenot1.55093497
41MP0003878_abnormal_ear_physiology1.55093497
42MP0001873_stomach_inflammation1.52906715
43MP0009379_abnormal_foot_pigmentation1.52766820
44MP0001764_abnormal_homeostasis1.51986064
45MP0006054_spinal_hemorrhage1.45669152
46MP0003122_maternal_imprinting1.43817971
47MP0002136_abnormal_kidney_physiology1.42547517
48MP0000467_abnormal_esophagus_morphology1.42533758
49MP0003566_abnormal_cell_adhesion1.39834407
50MP0005310_abnormal_salivary_gland1.37512184
51MP0005332_abnormal_amino_acid1.36113984
52MP0010352_gastrointestinal_tract_polyps1.35761261
53MP0005636_abnormal_mineral_homeostasis1.34889788
54MP0003879_abnormal_hair_cell1.34278215
55MP0002009_preneoplasia1.34172730
56MP0000762_abnormal_tongue_morphology1.31826038
57MP0010155_abnormal_intestine_physiology1.30237457
58MP0002138_abnormal_hepatobiliary_system1.30077475
59MP0000566_synostosis1.29219474
60MP0003195_calcinosis1.27300345
61MP0000537_abnormal_urethra_morphology1.25741435
62MP0003252_abnormal_bile_duct1.25508969
63MP0000427_abnormal_hair_cycle1.21349601
64MP0003866_abnormal_defecation1.12659823
65MP0003705_abnormal_hypodermis_morpholog1.11125953
66MP0001756_abnormal_urination1.09673804
67MP0005408_hypopigmentation1.09527498
68MP0001191_abnormal_skin_condition1.09004463
69MP0005058_abnormal_lysosome_morphology1.08386631
70MP0003718_maternal_effect1.08353118
71MP0005085_abnormal_gallbladder_physiolo1.06881437
72MP0001881_abnormal_mammary_gland1.05716106
73MP0000462_abnormal_digestive_system1.04779316
74MP0008961_abnormal_basal_metabolism1.01939394
75MP0002971_abnormal_brown_adipose1.01815855
76MP0002089_abnormal_postnatal_growth/wei1.01254134
77MP0003183_abnormal_peptide_metabolism0.98157648
78MP0005448_abnormal_energy_balance0.97960943
79MP0009115_abnormal_fat_cell0.96530946
80MP0010386_abnormal_urinary_bladder0.96500124
81MP0009931_abnormal_skin_appearance0.94400333
82MP0002132_abnormal_respiratory_system0.92297992
83MP0005319_abnormal_enzyme/_coenzyme0.92192163
84MP0005584_abnormal_enzyme/coenzyme_acti0.90204595
85MP0009642_abnormal_blood_homeostasis0.89978608
86MP0002166_altered_tumor_susceptibility0.87662989
87MP0000685_abnormal_immune_system0.87331605
88MP0000627_abnormal_mammary_gland0.86993073
89MP0000647_abnormal_sebaceous_gland0.86617973
90MP0004270_analgesia0.83134775
91MP0000604_amyloidosis0.83091626
92MP0004782_abnormal_surfactant_physiolog0.81526573
93MP0003172_abnormal_lysosome_physiology0.80972983
94MP0005365_abnormal_bile_salt0.80946740
95MP0003806_abnormal_nucleotide_metabolis0.79516883
96MP0000613_abnormal_salivary_gland0.78710556
97MP0000367_abnormal_coat/_hair0.77920473
98MP0005166_decreased_susceptibility_to0.76030103
99MP0008469_abnormal_protein_level0.74956876
100MP0001663_abnormal_digestive_system0.74349564
101MP0000477_abnormal_intestine_morphology0.72942785
102MP0000598_abnormal_liver_morphology0.72282839
103MP0005410_abnormal_fertilization0.72165779
104MP0002006_tumorigenesis0.71069606
105MP0004858_abnormal_nervous_system0.69713666
106MP0005381_digestive/alimentary_phenotyp0.69033353
107MP0005076_abnormal_cell_differentiation0.68941331
108MP0000516_abnormal_urinary_system0.68664669
109MP0005367_renal/urinary_system_phenotyp0.68664669
110MP0001664_abnormal_digestion0.68516421
111MP0010329_abnormal_lipoprotein_level0.68119727
112MP0009384_cardiac_valve_regurgitation0.67964495
113MP0002896_abnormal_bone_mineralization0.67626101
114MP0003763_abnormal_thymus_physiology0.65091758
115MP0002877_abnormal_melanocyte_morpholog0.64817626
116MP0004885_abnormal_endolymph0.63722688
117MP0003045_fibrosis0.63174246
118MP0006082_CNS_inflammation0.62993501
119MP0002234_abnormal_pharynx_morphology0.62652374
120MP0002078_abnormal_glucose_homeostasis0.62585180
121MP0000249_abnormal_blood_vessel0.62558862
122MP0008004_abnormal_stomach_pH0.62428194
123MP0005535_abnormal_body_temperature0.61183051
124MP0003638_abnormal_response/metabolism_0.60294063
125MP0005666_abnormal_adipose_tissue0.58513372
126MP0004185_abnormal_adipocyte_glucose0.58406034
127MP0005023_abnormal_wound_healing0.58269298
128MP0008260_abnormal_autophagy0.57347230
129MP0003329_amyloid_beta_deposits0.56605477
130MP0009785_altered_susceptibility_to0.56047788
131MP0004147_increased_porphyrin_level0.55063156
132MP0005334_abnormal_fat_pad0.54461986
133MP0003953_abnormal_hormone_level0.53385396
134MP0000678_abnormal_parathyroid_gland0.52952646
135MP0010368_abnormal_lymphatic_system0.52867692
136MP0004272_abnormal_basement_membrane0.52431366
137MP0009764_decreased_sensitivity_to0.52110451
138MP0000490_abnormal_crypts_of0.52016823
139MP0009780_abnormal_chondrocyte_physiolo0.51896540
140MP0005395_other_phenotype0.51041146
141MP0005376_homeostasis/metabolism_phenot0.50940754
142MP0000470_abnormal_stomach_morphology0.50938718
143MP0001851_eye_inflammation0.50599938
144MP0009697_abnormal_copulation0.49002401
145MP0001845_abnormal_inflammatory_respons0.46782752
146MP0005464_abnormal_platelet_physiology0.45572142
147MP0003436_decreased_susceptibility_to0.45491895
148MP0003123_paternal_imprinting0.41655374
149MP0001188_hyperpigmentation0.39282837
150MP0001915_intracranial_hemorrhage0.38773894
151MP0006138_congestive_heart_failure0.38745591
152MP0005257_abnormal_intraocular_pressure0.38744710
153MP0002135_abnormal_kidney_morphology0.36853523
154MP0002909_abnormal_adrenal_gland0.34908071

Predicted human phenotypes

RankGene SetZ-score
1Hypobetalipoproteinemia (HP:0003563)7.66891629
2Deep venous thrombosis (HP:0002625)6.90959143
3Right ventricular cardiomyopathy (HP:0011663)5.78752873
4Systemic lupus erythematosus (HP:0002725)5.36306594
5Complement deficiency (HP:0004431)5.05216546
6Hyperactive renin-angiotensin system (HP:0000841)4.91275838
7Xanthomatosis (HP:0000991)4.90352007
8Prolonged partial thromboplastin time (HP:0003645)4.82142357
9Acanthocytosis (HP:0001927)4.78121954
10Increased IgE level (HP:0003212)4.65790287
11Hypolipoproteinemia (HP:0010981)4.60948894
12Onycholysis (HP:0001806)4.57855453
13Abnormality of monocarboxylic acid metabolism (HP:0010996)4.54360949
14Abnormality of chloride homeostasis (HP:0011422)4.48788222
15Abnormality of nail color (HP:0100643)4.41469337
16Abnormality of glutamine family amino acid metabolism (HP:0010902)4.35055741
17Glomerulonephritis (HP:0000099)4.28608274
18Metabolic alkalosis (HP:0200114)4.28460350
19Fat malabsorption (HP:0002630)4.28128121
20Milia (HP:0001056)4.15881205
21Plantar hyperkeratosis (HP:0007556)4.15289733
22Abnormality of complement system (HP:0005339)4.11473296
23Hemorrhage of the eye (HP:0011885)4.08955069
24Joint hemorrhage (HP:0005261)4.06291859
25Lip pit (HP:0100267)3.98517761
26Congenital ichthyosiform erythroderma (HP:0007431)3.97108971
27Gout (HP:0001997)3.89782635
28Hypokalemic alkalosis (HP:0001949)3.87869970
29Increased circulating renin level (HP:0000848)3.86766768
30Pili torti (HP:0003777)3.82165430
31Dehydration (HP:0001944)3.76889495
32Abnormality of renal excretion (HP:0011036)3.73890254
33Hydroxyprolinuria (HP:0003080)3.69629305
34Abnormality of proline metabolism (HP:0010907)3.69629305
35Woolly hair (HP:0002224)3.57388907
36Fragile nails (HP:0001808)3.52033773
37Pigmentary retinal degeneration (HP:0001146)3.51824065
38Abnormality of the level of lipoprotein cholesterol (HP:0010979)3.48390477
39Hypomagnesemia (HP:0002917)3.47940868
40Abnormality of glycine metabolism (HP:0010895)3.46995805
41Abnormality of serine family amino acid metabolism (HP:0010894)3.46995805
42Abnormal urine output (HP:0012590)3.37119899
43Abnormality of the common coagulation pathway (HP:0010990)3.32105346
44Abnormality of the vitamin B12 metabolism (HP:0004341)3.29803718
45Palmoplantar hyperkeratosis (HP:0000972)3.29630344
46Hypercholesterolemia (HP:0003124)3.20478212
47Natal tooth (HP:0000695)3.20462307
48Confusion (HP:0001289)3.20259403
49Abnormality of aromatic amino acid family metabolism (HP:0004338)3.14533564
50Polyuria (HP:0000103)3.12399230
51Tetany (HP:0001281)3.10804996
52Abnormality of vitamin metabolism (HP:0100508)3.10735094
53Wide cranial sutures (HP:0010537)3.10667132
54Abnormality of purine metabolism (HP:0004352)3.07640907
55Hyperuricemia (HP:0002149)3.05197841
56Increased purine levels (HP:0004368)3.05197841
57Palmar hyperkeratosis (HP:0010765)3.05141408
58Abnormality of vitamin B metabolism (HP:0004340)3.04969314
59Abnormality of renin-angiotensin system (HP:0000847)3.00702122
60Advanced eruption of teeth (HP:0006288)2.99003818
61Renal salt wasting (HP:0000127)2.97858304
62Abnormality of magnesium homeostasis (HP:0004921)2.94283922
63Chronic diarrhea (HP:0002028)2.91394924
64Hyperaldosteronism (HP:0000859)2.89082133
65Hypoplasia of dental enamel (HP:0006297)2.87256242
66Atrophic scars (HP:0001075)2.83411970
67Conjugated hyperbilirubinemia (HP:0002908)2.82397154
68Curly hair (HP:0002212)2.80760137
69Malnutrition (HP:0004395)2.79694909
70Nephritis (HP:0000123)2.79496657
71Abnormality of the gastric mucosa (HP:0004295)2.79362904
72Nausea (HP:0002018)2.78833781
73Proximal tubulopathy (HP:0000114)2.78647200
74Intrahepatic cholestasis (HP:0001406)2.78284917
75Abnormality of small intestinal villus morphology (HP:0011472)2.73773675
76Villous atrophy (HP:0011473)2.73773675
77Hypophosphatemic rickets (HP:0004912)2.71241152
78Abnormal blistering of the skin (HP:0008066)2.65720582
79Renal tubular acidosis (HP:0001947)2.63176276
80Megaloblastic anemia (HP:0001889)2.61297768
81Hyperglycinuria (HP:0003108)2.61175120
82Steatorrhea (HP:0002570)2.58354364
83Nail dystrophy (HP:0008404)2.55731465
84Pustule (HP:0200039)2.55395412
85Hypophosphatemia (HP:0002148)2.54587795
86Congenital nonbullous ichthyosiform erythroderma (HP:0007479)2.52328853
87Abnormal hair laboratory examination (HP:0003328)2.51237385
88Ectropion (HP:0000656)2.48638005
89Spontaneous abortion (HP:0005268)2.47780884
90Vascular calcification (HP:0004934)2.45250133
91Hyperammonemia (HP:0001987)2.44377458
92Abnormality of carpal bone ossification (HP:0006257)2.44349193
93Ileus (HP:0002595)2.41320873
94Hyperlipoproteinemia (HP:0010980)2.39910259
95Poikilocytosis (HP:0004447)2.39042946
96Nephrolithiasis (HP:0000787)2.38998755
97Abnormal drinking behavior (HP:0030082)2.33300908
98Polydipsia (HP:0001959)2.33300908
99Abnormality of aspartate family amino acid metabolism (HP:0010899)2.29067561
100Hypotension (HP:0002615)2.28997600
101Alkalosis (HP:0001948)2.27600472
102Abnormal urine phosphate concentration (HP:0012599)2.26979000
103Widely patent fontanelles and sutures (HP:0004492)2.25708975
104Hypoalphalipoproteinemia (HP:0003233)2.25549749
105Menorrhagia (HP:0000132)2.23963868
106Osteomalacia (HP:0002749)2.22836074
107Gingival bleeding (HP:0000225)2.20925584
108Skin nodule (HP:0200036)2.20376967
109Cardiovascular calcification (HP:0011915)2.19650151
110Hypokalemia (HP:0002900)2.18578444
111Hypercalciuria (HP:0002150)2.15154960
112Erythroderma (HP:0001019)2.14609766
113Corneal erosion (HP:0200020)2.14444099
114Pruritus (HP:0000989)2.12173094
115Enlarged kidneys (HP:0000105)2.11191762
116Purpura (HP:0000979)2.10358820
117Amyloidosis (HP:0011034)2.09982628
118Parakeratosis (HP:0001036)2.09055163
119Glycosuria (HP:0003076)2.08510251
120Abnormality of urine glucose concentration (HP:0011016)2.08510251
121Potter facies (HP:0002009)2.07304911
122Facial shape deformation (HP:0011334)2.07304911
123Ketoacidosis (HP:0001993)2.06664438
124Hepatocellular carcinoma (HP:0001402)2.06187560
125Hypotrichosis (HP:0001006)2.06137925
126Hyperphosphatemia (HP:0002905)2.05178673
127Thin bony cortex (HP:0002753)2.00719043
128Abnormality of nucleobase metabolism (HP:0010932)1.97615627
129Recurrent gram-negative bacterial infections (HP:0005420)1.97416100
130Adrenal overactivity (HP:0002717)1.97174570
131Abnormality of pyrimidine metabolism (HP:0004353)1.95910397
132Subcapsular cataract (HP:0000523)1.95431275
133Abdominal distention (HP:0003270)1.94818967
134Myocardial infarction (HP:0001658)1.94329811
135Autoimmune thrombocytopenia (HP:0001973)1.91393890
136Epidermoid cyst (HP:0200040)1.90926309
137Abnormality of potassium homeostasis (HP:0011042)1.90686927
138Abnormal hand bone ossification (HP:0010660)1.89947522
139Abnormality of sulfur amino acid metabolism (HP:0004339)1.89803427
140Rickets (HP:0002748)1.89211186
141Glomerulosclerosis (HP:0000096)1.88831106
142Autoimmune hemolytic anemia (HP:0001890)1.88349873
143Vacuolated lymphocytes (HP:0001922)1.87241207
144Distal lower limb muscle weakness (HP:0009053)1.87126428
145Hepatoblastoma (HP:0002884)1.86289565
146Mitral stenosis (HP:0001718)1.84904500
147Flat acetabular roof (HP:0003180)1.84643290
148Hyperglycinemia (HP:0002154)1.84614575
149Fragile skin (HP:0001030)1.83683349
150Generalized aminoaciduria (HP:0002909)1.83212298
151Hypohidrosis (HP:0000966)1.82827793
152Abnormal ossification of hand bones (HP:0005921)1.81595511
153Ureteral stenosis (HP:0000071)1.81478820
154Abnormal tarsal ossification (HP:0008369)1.79260181
155Hyperphosphaturia (HP:0003109)1.79211159
156Interstitial pulmonary disease (HP:0006530)1.78890330
157Alopecia of scalp (HP:0002293)1.77490082
158Vaginal fistula (HP:0004320)1.76662722
159Aplasia cutis congenita (HP:0001057)1.75931881
160Abnormality of calcium-phosphate metabolism (HP:0100530)1.75878660
161Focal segmental glomerulosclerosis (HP:0000097)1.75765267
162Ventricular tachycardia (HP:0004756)1.75450851
163Abnormal hemoglobin (HP:0011902)1.75003689
164Delayed epiphyseal ossification (HP:0002663)1.74442537
165Abnormality of the nasal septum (HP:0000419)1.72122967
166Metabolic acidosis (HP:0001942)1.71715425
167Abnormality of alkaline phosphatase activity (HP:0004379)1.70817831
168Abnormal enzyme/coenzyme activity (HP:0012379)1.70784705
169Metaphyseal irregularity (HP:0003025)1.70566829

Predicted kinase interactions (KEA)

RankGene SetZ-score
1MST45.52435901
2ACVR1B5.17183301
3EPHA24.14766783
4WNK43.82078292
5FRK3.11708992
6MST1R3.08762414
7WNK32.96628965
8OXSR12.80956276
9STK392.39324976
10FER2.32633283
11MAP3K22.30129288
12EPHB12.27936942
13PTK62.19927877
14AKT32.10909483
15ICK2.06690181
16ERN12.02183932
17LATS12.00779586
18MAPKAPK32.00318845
19SIK11.81405994
20LRRK21.78746279
21MAP3K31.64744714
22MATK1.64345323
23EPHA31.61669960
24NME11.60221205
25EPHB21.58546791
26FGFR41.55308070
27TYRO31.53928581
28EEF2K1.53405424
29STK101.51899194
30CDK121.45255745
31PDPK11.43849833
32RPS6KB21.43175373
33LMTK21.42699388
34MAP3K101.37212708
35EPHA41.37119724
36MAP3K71.37114463
37MAPK111.29267042
38GRK61.24138619
39RIPK11.20827565
40PTK21.19867145
41MAP2K21.19337631
42CDC42BPA1.18174262
43FGFR21.15875559
44MAP3K141.15164935
45TESK21.13161213
46PDK11.11254726
47TRPM71.10831842
48DYRK1B1.09126328
49ERBB21.08461582
50TESK11.01618013
51MAPK150.99925202
52IRAK30.91014887
53NLK0.87959308
54PRKACG0.82355378
55PKN20.80064116
56CSF1R0.79433944
57PRKCI0.78787395
58ITK0.78128516
59TNK20.78055743
60FGR0.77638789
61ERBB30.75889373
62CDK60.75517818
63STK38L0.74276510
64MET0.73449645
65TYK20.73233903
66MAP3K110.71259614
67PIK3CA0.70536734
68FGFR30.69946276
69PRKCZ0.68055692
70PDGFRB0.67619346
71MAP4K10.67334923
72NUAK10.65947257
73BMX0.64288873
74WNK10.63119317
75KSR20.62853379
76TNIK0.61101189
77PRKG20.60966495
78BTK0.60074712
79CHUK0.58358553
80TBK10.57654458
81MAP3K10.56280269
82SGK2230.54880040
83SGK4940.54880040
84MAP3K120.54257919
85PIK3CG0.52640104
86TGFBR20.52531690
87RPS6KA10.51660337
88HIPK20.50963777
89PAK40.50241645
90STK30.49860406
91PAK30.49243688
92YES10.48985210
93MAPKAPK50.48515550
94TRIB30.48107679
95MAP2K60.47705876
96NME20.46779190
97JAK20.46479362
98PDK20.44709343
99IKBKE0.44655577
100FYN0.42953176
101JAK10.42569431
102STK380.42119978
103MYLK0.41911161
104IGF1R0.39461559
105JAK30.39118726
106DYRK30.38914179
107RET0.38051956
108SGK10.37687233
109PRKAA10.36495305
110MAPKAPK20.36261155
111ZAP700.36222088
112SMG10.35555758
113SRC0.34917189
114PRKCA0.34481764
115FGFR10.33255793
116MAP2K10.33172413
117PDGFRA0.33062694
118SCYL20.32648876
119DDR20.32587215
120PRKG10.32057958
121PDK30.31304249
122PDK40.31304249
123BRD40.30912575
124NEK60.30643197
125BCR0.30640617
126RIPK40.30472017
127GSK3A0.29507939
128PIM20.29408436
129TAOK30.28659543
130MAP3K80.28549006
131MELK0.28436103
132IRAK10.28210745
133TAOK10.27760214
134TGFBR10.27684295
135CSK0.27246637
136SGK30.26849206
137NEK90.26708363
138PRKAA20.25271343
139RPS6KB10.24134298
140INSRR0.23698076
141STK240.23274947
142CDK70.22573090
143LCK0.21430540

Predicted pathways (KEGG)

RankGene SetZ-score
1Cyanoamino acid metabolism_Homo sapiens_hsa004603.25815235
2Vitamin digestion and absorption_Homo sapiens_hsa049772.99443467
3Mineral absorption_Homo sapiens_hsa049782.94295773
4Complement and coagulation cascades_Homo sapiens_hsa046102.69925179
5Histidine metabolism_Homo sapiens_hsa003402.39852812
6Fat digestion and absorption_Homo sapiens_hsa049752.39773505
7Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049642.33775785
8Renin-angiotensin system_Homo sapiens_hsa046142.32470706
9Glutathione metabolism_Homo sapiens_hsa004802.28948675
10Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005122.07816129
11Sulfur metabolism_Homo sapiens_hsa009201.99367848
12Ascorbate and aldarate metabolism_Homo sapiens_hsa000531.97238808
13Protein digestion and absorption_Homo sapiens_hsa049741.94298502
14Drug metabolism - cytochrome P450_Homo sapiens_hsa009821.92502494
15Drug metabolism - other enzymes_Homo sapiens_hsa009831.87564789
16Caffeine metabolism_Homo sapiens_hsa002321.79375493
17Bile secretion_Homo sapiens_hsa049761.75802103
18Steroid hormone biosynthesis_Homo sapiens_hsa001401.72734671
19Primary bile acid biosynthesis_Homo sapiens_hsa001201.68371946
20Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009801.67985465
21Sphingolipid metabolism_Homo sapiens_hsa006001.64155629
22Pentose and glucuronate interconversions_Homo sapiens_hsa000401.60563944
23Carbohydrate digestion and absorption_Homo sapiens_hsa049731.59552947
24Chemical carcinogenesis_Homo sapiens_hsa052041.52071663
25Fatty acid degradation_Homo sapiens_hsa000711.46295193
26Collecting duct acid secretion_Homo sapiens_hsa049661.43995245
27Arachidonic acid metabolism_Homo sapiens_hsa005901.43837875
28Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004001.41551507
29Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008601.39741389
30Tryptophan metabolism_Homo sapiens_hsa003801.39592411
31Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049601.36824180
32Staphylococcus aureus infection_Homo sapiens_hsa051501.36079266
33beta-Alanine metabolism_Homo sapiens_hsa004101.35572216
34ABC transporters_Homo sapiens_hsa020101.33479853
35Phenylalanine metabolism_Homo sapiens_hsa003601.26257722
36Taurine and hypotaurine metabolism_Homo sapiens_hsa004301.22798246
37Valine, leucine and isoleucine degradation_Homo sapiens_hsa002801.19777154
38alpha-Linolenic acid metabolism_Homo sapiens_hsa005921.17538985
39Tight junction_Homo sapiens_hsa045301.14905837
40Adherens junction_Homo sapiens_hsa045201.13800820
41Bladder cancer_Homo sapiens_hsa052191.13443984
42Leukocyte transendothelial migration_Homo sapiens_hsa046701.11472552
43Glycine, serine and threonine metabolism_Homo sapiens_hsa002601.11386247
44Maturity onset diabetes of the young_Homo sapiens_hsa049501.10280594
45Thyroid hormone synthesis_Homo sapiens_hsa049181.10176726
46Starch and sucrose metabolism_Homo sapiens_hsa005001.09524932
47Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010401.06722228
482-Oxocarboxylic acid metabolism_Homo sapiens_hsa012101.05880095
49Propanoate metabolism_Homo sapiens_hsa006401.04572988
50PPAR signaling pathway_Homo sapiens_hsa033201.02569445
51Butanoate metabolism_Homo sapiens_hsa006501.02290307
52Butirosin and neomycin biosynthesis_Homo sapiens_hsa005240.99378429
53Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.98007480
54Pyruvate metabolism_Homo sapiens_hsa006200.93588159
55Galactose metabolism_Homo sapiens_hsa000520.88143133
56Glycerolipid metabolism_Homo sapiens_hsa005610.87451504
57Other glycan degradation_Homo sapiens_hsa005110.86479271
58Peroxisome_Homo sapiens_hsa041460.85377156
59Folate biosynthesis_Homo sapiens_hsa007900.85202832
60Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.84269523
61Linoleic acid metabolism_Homo sapiens_hsa005910.80925359
62Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.78706036
63Gastric acid secretion_Homo sapiens_hsa049710.76713807
64Hepatitis C_Homo sapiens_hsa051600.75276340
65Retinol metabolism_Homo sapiens_hsa008300.74604649
66Toxoplasmosis_Homo sapiens_hsa051450.73488872
67Primary immunodeficiency_Homo sapiens_hsa053400.72552031
68Biosynthesis of amino acids_Homo sapiens_hsa012300.70470950
69Synthesis and degradation of ketone bodies_Homo sapiens_hsa000720.69904913
70Vibrio cholerae infection_Homo sapiens_hsa051100.68368835
71Fatty acid metabolism_Homo sapiens_hsa012120.66308826
72ECM-receptor interaction_Homo sapiens_hsa045120.66067514
73Thyroid cancer_Homo sapiens_hsa052160.65882908
74Glycerophospholipid metabolism_Homo sapiens_hsa005640.64819856
75Amoebiasis_Homo sapiens_hsa051460.63551254
76Lysine degradation_Homo sapiens_hsa003100.63120856
77Endometrial cancer_Homo sapiens_hsa052130.62784893
78Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.62401519
79Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049610.59696807
80Small cell lung cancer_Homo sapiens_hsa052220.58901154
81Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054120.57018501
82Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006300.56673467
83Ether lipid metabolism_Homo sapiens_hsa005650.56509028
84Fructose and mannose metabolism_Homo sapiens_hsa000510.55299812
85Antigen processing and presentation_Homo sapiens_hsa046120.55280969
86Salivary secretion_Homo sapiens_hsa049700.54387036
87Carbon metabolism_Homo sapiens_hsa012000.54278277
88Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.53636610
89Tyrosine metabolism_Homo sapiens_hsa003500.52339829
90Fatty acid biosynthesis_Homo sapiens_hsa000610.51591226
91Adipocytokine signaling pathway_Homo sapiens_hsa049200.50147202
92Pertussis_Homo sapiens_hsa051330.49879288
93Steroid biosynthesis_Homo sapiens_hsa001000.47693613
94Proteoglycans in cancer_Homo sapiens_hsa052050.47640211
95Inflammatory bowel disease (IBD)_Homo sapiens_hsa053210.46293099
96Vitamin B6 metabolism_Homo sapiens_hsa007500.46241230
97Rheumatoid arthritis_Homo sapiens_hsa053230.45925193
98Arginine and proline metabolism_Homo sapiens_hsa003300.45272323
99Intestinal immune network for IgA production_Homo sapiens_hsa046720.44710234
100Legionellosis_Homo sapiens_hsa051340.43887363
101Pancreatic secretion_Homo sapiens_hsa049720.43857282
102Hematopoietic cell lineage_Homo sapiens_hsa046400.43536830
103Salmonella infection_Homo sapiens_hsa051320.42044556
104Arginine biosynthesis_Homo sapiens_hsa002200.42020370
105Citrate cycle (TCA cycle)_Homo sapiens_hsa000200.40029761
106Basal cell carcinoma_Homo sapiens_hsa052170.39924573
107Insulin resistance_Homo sapiens_hsa049310.38623073
108NOD-like receptor signaling pathway_Homo sapiens_hsa046210.38600430
109Leishmaniasis_Homo sapiens_hsa051400.38590456
110Hippo signaling pathway_Homo sapiens_hsa043900.38518085
111Glucagon signaling pathway_Homo sapiens_hsa049220.38423966
112Selenocompound metabolism_Homo sapiens_hsa004500.36036949
113Pentose phosphate pathway_Homo sapiens_hsa000300.35702207
114Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.34114241
115Pancreatic cancer_Homo sapiens_hsa052120.33826941
116NF-kappa B signaling pathway_Homo sapiens_hsa040640.33748998
117TNF signaling pathway_Homo sapiens_hsa046680.33267491
118Lysosome_Homo sapiens_hsa041420.31411853
119Metabolic pathways_Homo sapiens_hsa011000.29494357
120Glycosaminoglycan degradation_Homo sapiens_hsa005310.26823449
121Fatty acid elongation_Homo sapiens_hsa000620.24511342
122Sulfur relay system_Homo sapiens_hsa041220.22682202
123N-Glycan biosynthesis_Homo sapiens_hsa005100.15892890
124Prion diseases_Homo sapiens_hsa050200.14779074
125AMPK signaling pathway_Homo sapiens_hsa041520.13243427
126African trypanosomiasis_Homo sapiens_hsa051430.11535145
127Asthma_Homo sapiens_hsa053100.09974789
128Renin secretion_Homo sapiens_hsa049240.09785359
129Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.07934857
130Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.01822043
131Allograft rejection_Homo sapiens_hsa053300.00517148
132Chagas disease (American trypanosomiasis)_Homo sapiens_hsa05142-0.0645006
133Graft-versus-host disease_Homo sapiens_hsa05332-0.0486793
134Nitrogen metabolism_Homo sapiens_hsa00910-0.0462353
135Autoimmune thyroid disease_Homo sapiens_hsa05320-0.0093325
136Insulin signaling pathway_Homo sapiens_hsa04910-0.0073353

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