SLC44A2

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1antigen processing and presentation of endogenous peptide antigen (GO:0002483)5.71140694
2antigen processing and presentation of endogenous peptide antigen via MHC class I (GO:0019885)5.71140694
3positive regulation of gamma-delta T cell activation (GO:0046645)5.59570824
4antigen processing and presentation of endogenous antigen (GO:0019883)5.17742795
5regulation of gamma-delta T cell differentiation (GO:0045586)4.73663696
6modulation by organism of defense response of other organism involved in symbiotic interaction (GO:04.46044663
7positive regulation by organism of defense response of other organism involved in symbiotic interact4.46044663
8modulation by symbiont of host immune response (GO:0052553)4.46044663
9positive regulation by symbiont of host defense response (GO:0052509)4.46044663
10modulation by symbiont of host defense response (GO:0052031)4.46044663
11modulation by organism of immune response of other organism involved in symbiotic interaction (GO:004.46044663
12regulation of gamma-delta T cell activation (GO:0046643)4.34024588
13positive regulation of antigen receptor-mediated signaling pathway (GO:0050857)4.32558548
14neutrophil activation involved in immune response (GO:0002283)4.19668952
15detection of other organism (GO:0098543)4.00689631
16detection of bacterium (GO:0016045)3.96595063
17positive thymic T cell selection (GO:0045059)3.92984173
18regulation of interleukin-12 biosynthetic process (GO:0045075)3.70977876
19negative T cell selection (GO:0043383)3.70219095
20response to interleukin-15 (GO:0070672)3.69404025
21negative thymic T cell selection (GO:0045060)3.59943565
22regulation of B cell receptor signaling pathway (GO:0050855)3.58590269
23leukocyte migration involved in inflammatory response (GO:0002523)3.58056398
24negative regulation of lymphocyte mediated immunity (GO:0002707)3.55636974
25neutrophil activation (GO:0042119)3.55611527
26thymic T cell selection (GO:0045061)3.46800895
27negative regulation of leukocyte mediated cytotoxicity (GO:0001911)3.38670461
28negative regulation of cell killing (GO:0031342)3.38670461
29antigen processing and presentation via MHC class Ib (GO:0002475)3.34590742
30morphogenesis of an endothelium (GO:0003159)3.34325424
31endothelial tube morphogenesis (GO:0061154)3.34325424
32regulation of B cell differentiation (GO:0045577)3.30384981
33negative regulation of CD4-positive, alpha-beta T cell activation (GO:2000515)3.30366584
34regulation of T cell tolerance induction (GO:0002664)3.28208403
35leukocyte aggregation (GO:0070486)3.27043404
36B cell receptor signaling pathway (GO:0050853)3.24700407
37macrophage activation involved in immune response (GO:0002281)3.22074348
38detection of external biotic stimulus (GO:0098581)3.20471689
39positive regulation of Cdc42 GTPase activity (GO:0043089)3.19705958
40positive regulation of natural killer cell differentiation (GO:0032825)3.17323212
41negative regulation of leukocyte mediated immunity (GO:0002704)3.17243668
42antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G3.16741420
43negative regulation of amyloid precursor protein catabolic process (GO:1902992)3.14783506
44positive T cell selection (GO:0043368)3.13905583
45T cell selection (GO:0045058)3.13569877
46regulation of T-helper 2 cell differentiation (GO:0045628)3.11367206
47angiogenesis involved in wound healing (GO:0060055)3.08983394
48granulocyte activation (GO:0036230)3.08757732
49positive regulation of B cell differentiation (GO:0045579)3.07335324
50cellular response to interleukin-15 (GO:0071350)3.02058110
51negative regulation of phagocytosis (GO:0050765)3.01382440
52definitive hemopoiesis (GO:0060216)3.00446738
53response to muramyl dipeptide (GO:0032495)2.99100649
54cellular extravasation (GO:0045123)2.96258630
55response to host (GO:0075136)2.96245733
56response to host defenses (GO:0052200)2.96245733
57response to defenses of other organism involved in symbiotic interaction (GO:0052173)2.96245733
58regulation of mast cell degranulation (GO:0043304)2.95778042
59response to host immune response (GO:0052572)2.93776947
60response to immune response of other organism involved in symbiotic interaction (GO:0052564)2.93776947
61negative regulation of erythrocyte differentiation (GO:0045647)2.93710776
62signal complex assembly (GO:0007172)2.93327671
63respiratory burst (GO:0045730)2.88266434
64interferon-gamma production (GO:0032609)2.87613988
65positive regulation of tolerance induction (GO:0002645)2.84988084
66megakaryocyte development (GO:0035855)2.83324758
67positive regulation of histone deacetylation (GO:0031065)2.81350322
68regulation of leukocyte degranulation (GO:0043300)2.81069615
69natural killer cell differentiation (GO:0001779)2.80916930
70positive regulation of nitric-oxide synthase biosynthetic process (GO:0051770)2.80481759
71positive regulation of lamellipodium assembly (GO:0010592)2.79207641
72negative regulation of glycoprotein biosynthetic process (GO:0010561)2.78354231
73detection of biotic stimulus (GO:0009595)2.77768324
74regulation of myeloid leukocyte mediated immunity (GO:0002886)2.71050230
75negative regulation of T-helper cell differentiation (GO:0045623)2.70990043
76negative regulation of CD4-positive, alpha-beta T cell differentiation (GO:0043371)2.70990043
77detection of molecule of bacterial origin (GO:0032490)2.68157700
78response to peptidoglycan (GO:0032494)2.68063130
79Arp2/3 complex-mediated actin nucleation (GO:0034314)2.67758405
80regulation of defense response to virus by virus (GO:0050690)2.67251674
81T cell migration (GO:0072678)2.66378762
82regulation of type I interferon-mediated signaling pathway (GO:0060338)2.66330995
83regulation of interferon-gamma-mediated signaling pathway (GO:0060334)2.65784830
84activated T cell proliferation (GO:0050798)2.65684455
85regulation of response to interferon-gamma (GO:0060330)2.65682979
86dendritic cell chemotaxis (GO:0002407)2.65572126
87regulation of antigen receptor-mediated signaling pathway (GO:0050854)2.65001274
88antigen receptor-mediated signaling pathway (GO:0050851)2.64229110
89vascular endothelial growth factor signaling pathway (GO:0038084)2.63882297
90negative regulation of T cell mediated immunity (GO:0002710)2.63507700
91positive regulation of blood vessel endothelial cell migration (GO:0043536)2.63234210
92positive regulation of receptor recycling (GO:0001921)2.63045540
93regulation of mast cell activation involved in immune response (GO:0033006)2.62851156
94T cell homeostasis (GO:0043029)2.61853053
95hepatocyte apoptotic process (GO:0097284)2.61822500
96response to laminar fluid shear stress (GO:0034616)2.60957579
97regulation of platelet aggregation (GO:0090330)2.59541513
98JAK-STAT cascade involved in growth hormone signaling pathway (GO:0060397)2.58698569
99T cell costimulation (GO:0031295)2.58174288
100production of molecular mediator involved in inflammatory response (GO:0002532)2.57955380
1013-UTR-mediated mRNA stabilization (GO:0070935)2.57072623
102regulation of extracellular matrix disassembly (GO:0010715)2.56403250
103dendritic cell migration (GO:0036336)2.55313862
104leukocyte cell-cell adhesion (GO:0007159)2.55274277
105positive regulation of lamellipodium organization (GO:1902745)2.54608042
106regulation of dendritic cell antigen processing and presentation (GO:0002604)2.54110237
107T cell receptor signaling pathway (GO:0050852)2.54100856
108negative regulation of type 2 immune response (GO:0002829)2.53919168
109negative regulation of stress fiber assembly (GO:0051497)2.53817312
110regulation of tolerance induction (GO:0002643)2.53085171
111negative regulation of innate immune response (GO:0045824)2.51888943
112positive regulation of mast cell activation (GO:0033005)2.51721182
113lymphocyte costimulation (GO:0031294)2.51605265
114germ cell migration (GO:0008354)2.51513582
115positive regulation of protein deacetylation (GO:0090312)2.51503469
116positive regulation of T cell mediated cytotoxicity (GO:0001916)2.51382140
117regulation of T cell mediated cytotoxicity (GO:0001914)2.47408553
118myeloid cell activation involved in immune response (GO:0002275)2.47278260
119tolerance induction (GO:0002507)2.46835692
120negative regulation of lipopolysaccharide-mediated signaling pathway (GO:0031665)2.46730998
121positive regulation of interleukin-2 biosynthetic process (GO:0045086)2.46627287
122positive regulation of cellular amide metabolic process (GO:0034250)2.45311281
123mast cell activation (GO:0045576)2.42832918
124regulation of regulated secretory pathway (GO:1903305)2.42074821
125cellular response to zinc ion (GO:0071294)2.42006856
126regulation of humoral immune response mediated by circulating immunoglobulin (GO:0002923)2.41661174
127blood vessel maturation (GO:0001955)2.41657214
128regulation of macrophage cytokine production (GO:0010935)2.41226702
129leukocyte degranulation (GO:0043299)2.41027184
130regulation of Cdc42 GTPase activity (GO:0043088)2.39371368
131regulation of natural killer cell differentiation (GO:0032823)2.38722343
132lipopolysaccharide biosynthetic process (GO:0009103)2.38569106
133response to type I interferon (GO:0034340)2.38384611
134peptidyl-tyrosine autophosphorylation (GO:0038083)2.37954086
135regulation of necroptotic process (GO:0060544)2.37704894
136pinocytosis (GO:0006907)2.37471295
137NIK/NF-kappaB signaling (GO:0038061)2.37020585
138stress fiber assembly (GO:0043149)2.36202048
139interferon-gamma-mediated signaling pathway (GO:0060333)2.35803450
140lymphocyte homeostasis (GO:0002260)2.35316201
141keratan sulfate catabolic process (GO:0042340)2.34954914
142embryonic hemopoiesis (GO:0035162)2.33293628
143lymph node development (GO:0048535)2.33223639
144regulation of T cell receptor signaling pathway (GO:0050856)2.33199339
145positive regulation of type I interferon-mediated signaling pathway (GO:0060340)2.32353433
146cellular response to vascular endothelial growth factor stimulus (GO:0035924)2.31643730
147regulation of alpha-beta T cell proliferation (GO:0046640)2.28511091
148type I interferon signaling pathway (GO:0060337)2.28472086
149cellular response to type I interferon (GO:0071357)2.28472086
150establishment of endothelial barrier (GO:0061028)2.25739236
151skin morphogenesis (GO:0043589)2.22466807
152germinal center formation (GO:0002467)2.20494370
153positive regulation of tumor necrosis factor biosynthetic process (GO:0042535)2.18788538
154positive regulation of granulocyte differentiation (GO:0030854)2.18747640
155natural killer cell activation (GO:0030101)2.18649972
156regulation of natural killer cell mediated immunity (GO:0002715)2.17700587
157regulation of natural killer cell mediated cytotoxicity (GO:0042269)2.17700587
158cellular hyperosmotic response (GO:0071474)2.16651205
159regulation of interferon-beta biosynthetic process (GO:0045357)2.16594081
160positive regulation of interleukin-2 production (GO:0032743)2.14129486
161muscle filament sliding (GO:0030049)2.13614524
162actin-myosin filament sliding (GO:0033275)2.13614524
163immune response-activating cell surface receptor signaling pathway (GO:0002429)2.13075308

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1FOXP3_17237761_ChIP-ChIP_TREG_Mouse4.66841078
2STAT6_20620947_ChIP-Seq_CD4_POS_T_Human4.30109500
3EGR1_19374776_ChIP-ChIP_THP-1_Human3.72188436
4IRF8_22096565_ChIP-ChIP_GC-B_Human3.49931344
5MYC_22102868_ChIP-Seq_BL_Human3.47762539
6NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse3.21909834
7E2F7_22180533_ChIP-Seq_HELA_Human3.08149629
8* MECOM_23826213_ChIP-Seq_KASUMI_Mouse2.86093455
9VDR_21846776_ChIP-Seq_THP-1_Human2.82085009
10* MAF_26560356_Chip-Seq_TH1_Human2.53201411
11SCL_19346495_ChIP-Seq_HPC-7_Human2.49335120
12RUNX_20019798_ChIP-Seq_JUKART_Human2.42628115
13MYB_26560356_Chip-Seq_TH2_Human2.41776123
14FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse2.35028083
15TCF7_22412390_ChIP-Seq_EML_Mouse2.31622246
16TP63_17297297_ChIP-ChIP_HaCaT_Human2.24622325
17* UTX_26944678_Chip-Seq_JUKART_Human2.23086673
18MYB_21317192_ChIP-Seq_ERMYB_Mouse2.22546902
19STAT3_20064451_ChIP-Seq_CD4+T_Mouse2.20549233
20IRF8_22096565_ChIP-ChIP_GC-B_Mouse2.19000790
21* ELK3_25401928_ChIP-Seq_HUVEC_Human2.11997096
22SPI1_22096565_ChIP-ChIP_GC-B_Mouse2.10332571
23RUNX1_20887958_ChIP-Seq_HPC-7_Mouse2.06474717
24BP1_19119308_ChIP-ChIP_Hs578T_Human2.02787475
25* MYB_26560356_Chip-Seq_TH1_Human2.01790365
26NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse2.00309431
27VDR_24763502_ChIP-Seq_THP-1_Human1.99798795
28STAT4_19710469_ChIP-ChIP_TH1__Mouse1.98999484
29IRF1_21803131_ChIP-Seq_MONOCYTES_Human1.98947272
30KDM2B_26808549_Chip-Seq_DND41_Human1.94696477
31KDM2B_26808549_Chip-Seq_SUP-B15_Human1.94555423
32KDM2B_26808549_Chip-Seq_SIL-ALL_Human1.93420634
33SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse1.88672279
34IRF8_27001747_Chip-Seq_BMDM_Mouse1.85264174
35IRF8_21731497_ChIP-ChIP_J774_Mouse1.84600966
36E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human1.84353738
37BRD4_27068464_Chip-Seq_AML-cells_Mouse1.83798068
38KDM2B_26808549_Chip-Seq_HPB-ALL_Human1.82897697
39RUNX1_22412390_ChIP-Seq_EML_Mouse1.80507146
40ASXL1_24218140_ChIP-Seq_BMDM_Mouse1.76767476
41SPI1_23127762_ChIP-Seq_K562_Human1.75163176
42NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human1.73259580
43RARG_19884340_ChIP-ChIP_MEFs_Mouse1.70985155
44* SPI1_23547873_ChIP-Seq_NB4_Human1.69565863
45SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse1.68861856
46TFAP2C_20629094_ChIP-Seq_MCF-7_Human1.63517958
47RUNX2_24764292_ChIP-Seq_MC3T3_Mouse1.62789914
48ZFP281_18757296_ChIP-ChIP_E14_Mouse1.62300346
49KDM2B_26808549_Chip-Seq_K562_Human1.59951462
50FOXM1_23109430_ChIP-Seq_U2OS_Human1.59313439
51MAF_26560356_Chip-Seq_TH2_Human1.52530094
52* GATA3_27048872_Chip-Seq_THYMUS_Human1.47810827
53TCF21_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human1.45703571
54CIITA_25753668_ChIP-Seq_RAJI_Human1.44117581
55CTCF_27219007_Chip-Seq_ERYTHROID_Human1.41487540
56EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.41108111
57SA1_27219007_Chip-Seq_ERYTHROID_Human1.40902326
58KLF6_26769127_Chip-Seq_PDAC-Cell_line_Human1.40525818
59RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human1.38808785
60* CLOCK_20551151_ChIP-Seq_293T_Human1.38393743
61SCL_21571218_ChIP-Seq_MEGAKARYOCYTES_Human1.38344148
62TAL1_20887958_ChIP-Seq_HPC-7_Mouse1.37454822
63MEIS1_20887958_ChIP-Seq_HPC-7_Mouse1.37345221
64NOTCH1_21737748_ChIP-Seq_TLL_Human1.36345294
65FLI1_20887958_ChIP-Seq_HPC-7_Mouse1.33679591
66TRIM28_21343339_ChIP-Seq_HEK293_Human1.30920850
67EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse1.29688159
68TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse1.29668627
69GATA2_21571218_ChIP-Seq_MEGAKARYOCYTES_Human1.28688721
70SMC4_20622854_ChIP-Seq_HELA_Human1.28381308
71* EGR1_20690147_ChIP-Seq_ERYTHROLEUKEMIA_Human1.27669931
72GATA2_21666600_ChIP-Seq_HMVEC_Human1.27153962
73TAL1_20566737_ChIP-Seq_PRIMARY_FETAL_LIVER_ERYTHROID_Mouse1.26497227
74P68_20966046_ChIP-Seq_HELA_Human1.25054873
75STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse1.24626384
76SMAD3_22036565_ChIP-Seq_ESCs_Mouse1.22735301
77CEBPB_20176806_ChIP-Seq_MACROPHAGES_Mouse1.22579640
78* RUNX1_27514584_Chip-Seq_MCF-7_Human1.22555885
79ESR1_20079471_ChIP-ChIP_T-47D_Human1.22117324
80EP300_20729851_ChIP-Seq_FORBRAIN_MIDBRAIN_LIMB_HEART_Mouse1.21892904
81NCOR1_26117541_ChIP-Seq_K562_Human1.21032756
82SFPI1_20887958_ChIP-Seq_HPC-7_Mouse1.20578604
83PU.1_20176806_ChIP-Seq_MACROPHAGES_Mouse1.19047036
84KDM2B_26808549_Chip-Seq_JURKAT_Human1.18445489
85SRY_22984422_ChIP-ChIP_TESTIS_Rat1.18112547
86* GATA1_19941826_ChIP-Seq_K562_Human1.17103358
87LXR_22292898_ChIP-Seq_THP-1_Human1.16714300
88GATA2_22383799_ChIP-Seq_G1ME_Mouse1.14643371
89IKZF1_21737484_ChIP-ChIP_HCT116_Human1.12910846
90BCL6_27268052_Chip-Seq_Bcells_Human1.12545097
91WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse1.12310211
92TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse1.12299281
93GATA1_22383799_ChIP-Seq_G1ME_Mouse1.12068018
94THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse1.11006304
95HIF1A_21447827_ChIP-Seq_MCF-7_Human1.10798580
96BCOR_27268052_Chip-Seq_Bcells_Human1.09482454
97ZFP281_27345836_Chip-Seq_ESCs_Mouse1.09212928
98ZFP281_18358816_ChIP-ChIP_MESCs_Mouse1.09206463
99CEBPB_21427703_ChIP-Seq_3T3-L1_Mouse1.09197350
100RACK7_27058665_Chip-Seq_MCF-7_Human1.09156481
101UBF1/2_26484160_Chip-Seq_HMEC-DERIVED_Human1.08894378
102DNAJC2_21179169_ChIP-ChIP_NT2_Human1.08790244
103PU.1_20513432_ChIP-Seq_MACROPHAGES_Mouse1.08309776
104FOXP2_23625967_ChIP-Seq_PFSK-1_AND_SK-N-MC_Human1.07755342
105P63_26484246_Chip-Seq_KERATINOCYTES_Human1.07023503
106ESR1_21235772_ChIP-Seq_MCF-7_Human1.06804323
107PU_27001747_Chip-Seq_BMDM_Mouse1.06092874
108KLF4_26769127_Chip-Seq_PDAC-Cell_line_Human1.03496313
109STAT6_21828071_ChIP-Seq_BEAS2B_Human1.03133152
110SMAD2_18955504_ChIP-ChIP_HaCaT_Human1.03085719
111SMAD3_18955504_ChIP-ChIP_HaCaT_Human1.03085719
112PU.1_20513432_ChIP-Seq_Bcells_Mouse1.02879997
113* TBX20_22328084_ChIP-Seq_HEART_Mouse1.01704682
114* TBX20_22080862_ChIP-Seq_HEART_Mouse1.01704682
115CREB1_26743006_Chip-Seq_LNCaP_Human1.00364218
116SPI1_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse1.00307686
117P300_27058665_Chip-Seq_ZR-75-30cells_Human0.99129813
118TP63_22573176_ChIP-Seq_HFKS_Human0.98951104
119LMO2_20887958_ChIP-Seq_HPC-7_Mouse0.97786615
120NFE2L2_22581777_ChIP-Seq_LYMPHOBLASTOID_Human0.97783491
121ELF3_26769127_Chip-Seq_PDAC-Cell_line_Human0.97555986
122* GATA1_19941827_ChIP-Seq_MEL_Mouse0.96575384
123ESR2_21235772_ChIP-Seq_MCF-7_Human0.96199822
124NKX2-5_21415370_ChIP-Seq_HL-1_Mouse0.92959669
125VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human0.92791548
126SMAD_19615063_ChIP-ChIP_OVARY_Human0.92752607
127GFI1B_20887958_ChIP-Seq_HPC-7_Mouse0.92433387
128ATF3_27146783_Chip-Seq_COLON_Human0.91858009
129FOXO3_23340844_ChIP-Seq_DLD1_Human0.91420941
130GATA2_20887958_ChIP-Seq_HPC-7_Mouse0.90343084
131SMARCA4_20176728_ChIP-ChIP_TSCs_Mouse0.88901569
132CEBPB_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse0.88423800
133CTCF_21964334_Chip-Seq_Bcells_Human0.85027546

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0003763_abnormal_thymus_physiology2.69574115
2MP0002396_abnormal_hematopoietic_system2.61956704
3MP0000685_abnormal_immune_system2.54516732
4MP0001835_abnormal_antigen_presentation2.49803395
5MP0003191_abnormal_cellular_cholesterol2.48626522
6MP0003279_aneurysm2.40932104
7MP0006054_spinal_hemorrhage2.37638509
8MP0008438_abnormal_cutaneous_collagen2.37515354
9MP0008260_abnormal_autophagy2.27779033
10MP0002933_joint_inflammation2.23615537
11MP0003300_gastrointestinal_ulcer2.23551393
12MP0001958_emphysema2.17238913
13MP0002166_altered_tumor_susceptibility2.12272460
14MP0004808_abnormal_hematopoietic_stem2.10538886
15MP0004381_abnormal_hair_follicle2.06878206
16MP0001800_abnormal_humoral_immune2.01972116
17MP0005671_abnormal_response_to1.97486173
18MP0004858_abnormal_nervous_system1.91777544
19MP0003705_abnormal_hypodermis_morpholog1.89220497
20MP0001790_abnormal_immune_system1.88319054
21MP0005387_immune_system_phenotype1.88319054
22MP0003436_decreased_susceptibility_to1.86807250
23MP0003566_abnormal_cell_adhesion1.86141365
24MP0002398_abnormal_bone_marrow1.84322625
25MP0002452_abnormal_antigen_presenting1.80989222
26MP0005503_abnormal_tendon_morphology1.80043162
27MP0002420_abnormal_adaptive_immunity1.77621819
28MP0001819_abnormal_immune_cell1.74320610
29MP0009278_abnormal_bone_marrow1.70591344
30MP0010352_gastrointestinal_tract_polyps1.69775988
31MP0005275_abnormal_skin_tensile1.68265698
32MP0000465_gastrointestinal_hemorrhage1.66079609
33MP0005000_abnormal_immune_tolerance1.65479969
34MP0002723_abnormal_immune_serum1.64364288
35MP0003878_abnormal_ear_physiology1.63979969
36MP0005377_hearing/vestibular/ear_phenot1.63979969
37MP0005023_abnormal_wound_healing1.62328676
38MP0001873_stomach_inflammation1.58960677
39MP0003303_peritoneal_inflammation1.57192939
40MP0000716_abnormal_immune_system1.55258644
41MP0002405_respiratory_system_inflammati1.53955443
42MP0001849_ear_inflammation1.53909774
43MP0004947_skin_inflammation1.52234792
44MP0005464_abnormal_platelet_physiology1.51610557
45MP0000703_abnormal_thymus_morphology1.50928705
46MP0002132_abnormal_respiratory_system1.50670557
47MP0000689_abnormal_spleen_morphology1.50018608
48MP0002722_abnormal_immune_system1.49752461
49MP0002653_abnormal_ependyma_morphology1.47638620
50MP0002006_tumorigenesis1.47603095
51MP0009785_altered_susceptibility_to1.47323119
52MP0009333_abnormal_splenocyte_physiolog1.46773433
53MP0005025_abnormal_response_to1.45788814
54MP0004084_abnormal_cardiac_muscle1.43497747
55MP0010368_abnormal_lymphatic_system1.42439414
56MP0010155_abnormal_intestine_physiology1.40493017
57MP0002419_abnormal_innate_immunity1.39564801
58MP0004883_abnormal_blood_vessel1.38882947
59MP0000733_abnormal_muscle_development1.38739722
60MP0001533_abnormal_skeleton_physiology1.37584911
61MP0001879_abnormal_lymphatic_vessel1.37203780
62MP0001545_abnormal_hematopoietic_system1.37203014
63MP0005397_hematopoietic_system_phenotyp1.37203014
64MP0002429_abnormal_blood_cell1.34865143
65MP0004510_myositis1.32661869
66MP0005451_abnormal_body_composition1.29120192
67MP0000343_altered_response_to1.27991837
68MP0000751_myopathy1.27803699
69MP0003091_abnormal_cell_migration1.25207681
70MP0000767_abnormal_smooth_muscle1.24999278
71MP0003183_abnormal_peptide_metabolism1.24456098
72MP0000858_altered_metastatic_potential1.22948314
73MP0005083_abnormal_biliary_tract1.20123893
74MP0005248_abnormal_Harderian_gland1.19327829
75MP0002796_impaired_skin_barrier1.19077428
76MP0003453_abnormal_keratinocyte_physiol1.18769862
77MP0003724_increased_susceptibility_to1.18043879
78MP0001853_heart_inflammation1.15870498
79MP0008004_abnormal_stomach_pH1.15732123
80MP0002148_abnormal_hypersensitivity_rea1.14292206
81MP0004264_abnormal_extraembryonic_tissu1.12134458
82MP0003828_pulmonary_edema1.11800090
83MP0003646_muscle_fatigue1.11790212
84MP0006082_CNS_inflammation1.05819330
85MP0003448_altered_tumor_morphology1.03821417
86MP0003045_fibrosis1.03591281
87MP0001845_abnormal_inflammatory_respons1.02658595
88MP0003172_abnormal_lysosome_physiology1.00678642
89MP0009384_cardiac_valve_regurgitation1.00069759
90MP0005390_skeleton_phenotype0.99695111
91MP0005076_abnormal_cell_differentiation0.99664773
92MP0000750_abnormal_muscle_regeneration0.97674401
93MP0002060_abnormal_skin_morphology0.96848826
94MP0002998_abnormal_bone_remodeling0.96745816
95MP0002254_reproductive_system_inflammat0.96601622
96MP0000749_muscle_degeneration0.96261522
97MP0004087_abnormal_muscle_fiber0.96163265
98MP0002089_abnormal_postnatal_growth/wei0.94777443
99MP0004130_abnormal_muscle_cell0.93046009
100MP0004134_abnormal_chest_morphology0.93011811
101MP0008007_abnormal_cellular_replicative0.92843879
102MP0000490_abnormal_crypts_of0.89977172
103MP0002133_abnormal_respiratory_system0.89928121
104MP0005388_respiratory_system_phenotype0.89928121
105MP0001851_eye_inflammation0.89894979
106MP0004036_abnormal_muscle_relaxation0.89405617
107MP0003866_abnormal_defecation0.89240690
108MP0010630_abnormal_cardiac_muscle0.88046703
109MP0000249_abnormal_blood_vessel0.88036408
110MP0010030_abnormal_orbit_morphology0.87958107
111MP0000747_muscle_weakness0.86357509
112MP0002128_abnormal_blood_circulation0.85814989
113MP0002019_abnormal_tumor_incidence0.83925561
114MP0001243_abnormal_dermal_layer0.83858380
115MP0001663_abnormal_digestive_system0.83659410
116MP0001348_abnormal_lacrimal_gland0.83428512
117MP0003795_abnormal_bone_structure0.83237082
118MP0005164_abnormal_response_to0.82886260
119MP0005501_abnormal_skin_physiology0.82491568
120MP0002106_abnormal_muscle_physiology0.81755369
121MP0003329_amyloid_beta_deposits0.78066711
122MP0002925_abnormal_cardiovascular_devel0.78063370
123MP0008874_decreased_physiological_sensi0.77716450
124MP0000759_abnormal_skeletal_muscle0.77316525
125MP0008961_abnormal_basal_metabolism0.76317661
126MP0004272_abnormal_basement_membrane0.75986471
127MP0005508_abnormal_skeleton_morphology0.75252832
128MP0005058_abnormal_lysosome_morphology0.74807688
129MP0001915_intracranial_hemorrhage0.74753656
130MP0002113_abnormal_skeleton_development0.73439029
131MP0002877_abnormal_melanocyte_morpholog0.72253227
132MP0005310_abnormal_salivary_gland0.70509775
133MP0003690_abnormal_glial_cell0.69841054
134MP0005381_digestive/alimentary_phenotyp0.67698180
135MP0000377_abnormal_hair_follicle0.66376153
136MP0008469_abnormal_protein_level0.64635644
137MP0003075_altered_response_to0.63738079

Predicted human phenotypes

RankGene SetZ-score
1Prolonged bleeding time (HP:0003010)3.92017425
2Abnormality of macrophages (HP:0004311)3.75053621
3Orchitis (HP:0100796)3.50981514
4Aortic aneurysm (HP:0004942)3.33666200
5Protrusio acetabuli (HP:0003179)3.18023643
6Abnormal platelet volume (HP:0011876)3.16613399
7Ulnar deviation of the wrist (HP:0003049)3.08364086
8Optic neuritis (HP:0100653)3.00370045
9Retrobulbar optic neuritis (HP:0100654)3.00370045
10Chronic otitis media (HP:0000389)2.92377259
11Cerebral aneurysm (HP:0004944)2.91315171
12Obstructive sleep apnea (HP:0002870)2.91076719
13Stomatitis (HP:0010280)2.86876633
14Epiphyseal dysplasia (HP:0002656)2.86112835
15Petechiae (HP:0000967)2.81945601
16Epistaxis (HP:0000421)2.76761095
17Type 1 muscle fiber predominance (HP:0003803)2.74269655
18Recurrent bronchitis (HP:0002837)2.71970831
19Gastrointestinal infarctions (HP:0005244)2.68525927
20Abnormality of the nasal mucosa (HP:0000433)2.68293449
21Meningitis (HP:0001287)2.68102224
22Spondylolisthesis (HP:0003302)2.65783667
23Chronic obstructive pulmonary disease (HP:0006510)2.65434964
24Obstructive lung disease (HP:0006536)2.65434964
25Elevated erythrocyte sedimentation rate (HP:0003565)2.64056306
26Recurrent gram-negative bacterial infections (HP:0005420)2.63928508
27Interstitial pulmonary disease (HP:0006530)2.63269406
28Peritonitis (HP:0002586)2.63041250
29Gingivitis (HP:0000230)2.57507913
30Absent frontal sinuses (HP:0002688)2.56733884
31Abnormality of the fingertips (HP:0001211)2.55603056
32Broad face (HP:0000283)2.55246170
33Hematochezia (HP:0002573)2.54872865
34Aortic dissection (HP:0002647)2.54459377
35Ankle contracture (HP:0006466)2.52623993
36Broad metatarsal (HP:0001783)2.52270558
37Gingival bleeding (HP:0000225)2.52123820
38Increased mean platelet volume (HP:0011877)2.51008111
39Myositis (HP:0100614)2.50993689
40Recurrent viral infections (HP:0004429)2.50419668
41Cervical subluxation (HP:0003308)2.50392195
42Menorrhagia (HP:0000132)2.49517364
43Increased variability in muscle fiber diameter (HP:0003557)2.48020219
44Spontaneous hematomas (HP:0007420)2.47009106
45Hypoplastic ischia (HP:0003175)2.46873943
46Purpura (HP:0000979)2.44272090
47Thrombocytosis (HP:0001894)2.43617203
48T lymphocytopenia (HP:0005403)2.39831618
49Hypochromic microcytic anemia (HP:0004840)2.39298210
50Metaphyseal cupping (HP:0003021)2.38328700
51Small epiphyses (HP:0010585)2.36541184
52Chest pain (HP:0100749)2.35890548
53Abnormality of the calcaneus (HP:0008364)2.34481333
54Eczematoid dermatitis (HP:0000976)2.33571273
55Nasal polyposis (HP:0100582)2.33257862
56Cellulitis (HP:0100658)2.33103953
57Muscle fiber cytoplasmatic inclusion bodies (HP:0100303)2.32398106
58Distal lower limb muscle weakness (HP:0009053)2.31250599
59Muscle fiber inclusion bodies (HP:0100299)2.30704716
60Lumbar hyperlordosis (HP:0002938)2.29222798
61Increased density of long bones (HP:0006392)2.28386220
62Recurrent fungal infections (HP:0002841)2.26950279
63Syringomyelia (HP:0003396)2.26255018
64Spinal cord lesions (HP:0100561)2.26255018
65Encephalitis (HP:0002383)2.25574039
66Abnormality of T cell number (HP:0011839)2.25068126
67Urticaria (HP:0001025)2.24845146
68Mediastinal lymphadenopathy (HP:0100721)2.24575325
69Abnormal foot bone ossification (HP:0010675)2.24305031
70Ulnar bowing (HP:0003031)2.21973646
71Keratoconjunctivitis sicca (HP:0001097)2.21833683
72IgM deficiency (HP:0002850)2.21796907
73Recurrent skin infections (HP:0001581)2.21412640
74Vasculitis (HP:0002633)2.21206560
75Limited elbow extension (HP:0001377)2.20372107
76Flat acetabular roof (HP:0003180)2.18669101
77Recurrent abscess formation (HP:0002722)2.17905617
78Pustule (HP:0200039)2.16912905
79Easy fatigability (HP:0003388)2.16219347
80Radial bowing (HP:0002986)2.15888555
81Increased connective tissue (HP:0009025)2.13701791
82Nemaline bodies (HP:0003798)2.12460293
83Distal arthrogryposis (HP:0005684)2.10834225
84Metaphyseal dysplasia (HP:0100255)2.10444754
85Irregular epiphyses (HP:0010582)2.09931631
86Dilatation of the ascending aorta (HP:0005111)2.08203111
87Premature rupture of membranes (HP:0001788)2.06768873
88Emphysema (HP:0002097)2.06721720
89Abnormality of the ischium (HP:0003174)2.05605466
90Hypochromic anemia (HP:0001931)2.03968410
91Aplasia/Hypoplasia of the pubic bone (HP:0009104)2.02513099
92Mesomelia (HP:0003027)2.01639997
93Long clavicles (HP:0000890)2.01333277
94Cupped ribs (HP:0000887)2.00719403
95Broad palm (HP:0001169)2.00671741
96Chronic mucocutaneous candidiasis (HP:0002728)1.99375963
97Recurrent cutaneous fungal infections (HP:0011370)1.99375963
98Sepsis (HP:0100806)1.97995172
99Episodic fever (HP:0001954)1.97597009
100Distal lower limb amyotrophy (HP:0008944)1.96859711
101Joint stiffness (HP:0001387)1.96763249
102Vascular tortuosity (HP:0004948)1.96130519
103Keratoconjunctivitis (HP:0001096)1.95946662
104Difficulty running (HP:0009046)1.95201767
105Papilloma (HP:0012740)1.94478773
106Verrucae (HP:0200043)1.94478773
107Gastrointestinal stroma tumor (HP:0100723)1.94389090
108Aplasia/Hypoplasia of the frontal sinuses (HP:0009119)1.93751969
109Panhypogammaglobulinemia (HP:0003139)1.93412725
110Recurrent bacterial skin infections (HP:0005406)1.93280572
111Osteolytic defects of the phalanges of the hand (HP:0009771)1.92915326
112Osteolytic defects of the hand bones (HP:0009699)1.92915326
113Abnormality of skeletal muscle fiber size (HP:0012084)1.92277898
114Abnormality of T cells (HP:0002843)1.91934198
115Persistence of primary teeth (HP:0006335)1.91447543
116Hypergammaglobulinemia (HP:0010702)1.90961872
117Muscle fiber splitting (HP:0003555)1.90762448
118Increased IgM level (HP:0003496)1.90132258
119Coxa vara (HP:0002812)1.89566023
120Polycythemia (HP:0001901)1.89524073
121Colitis (HP:0002583)1.89358607
122Abnormal vertebral ossification (HP:0100569)1.88314495
123Mitral valve prolapse (HP:0001634)1.86082278
124Parkinsonism with favorable response to dopaminergic medication (HP:0002548)1.85741192
125Aneurysm (HP:0002617)1.85491836
126Segmental peripheral demyelination/remyelination (HP:0003481)1.83425573
127Agammaglobulinemia (HP:0004432)1.83222462
128Osteomyelitis (HP:0002754)1.83005847
129Arterial thrombosis (HP:0004420)1.82599330
130Arterial tortuosity (HP:0005116)1.82421214
131Frequent falls (HP:0002359)1.82131964
132Shallow orbits (HP:0000586)1.80435105
133Platyspondyly (HP:0000926)1.79482462
134Hyporeflexia of lower limbs (HP:0002600)1.79444022
135Granulocytopenia (HP:0001913)1.78920045
136Abnormal delayed hypersensitivity skin test (HP:0002963)1.78903635
137Bruising susceptibility (HP:0000978)1.77698965
138Flattened epiphyses (HP:0003071)1.77641426
139Leukocytosis (HP:0001974)1.77368434
140Disproportionate tall stature (HP:0001519)1.76999076
141Bowed forearm bones (HP:0003956)1.76383598
142Bowing of the arm (HP:0006488)1.76383598
143Restrictive lung disease (HP:0002091)1.76373024
144Dislocated radial head (HP:0003083)1.75970133
145Calcaneovalgus deformity (HP:0001848)1.75747978
146Lymphopenia (HP:0001888)1.75715638
147Bicuspid aortic valve (HP:0001647)1.75555015
148Round ear (HP:0100830)1.74859225
149Hepatosplenomegaly (HP:0001433)1.74236044
150Gastrointestinal inflammation (HP:0004386)1.73617563
151Slow saccadic eye movements (HP:0000514)1.73191360
152Slender build (HP:0001533)1.73171148
153Chronic sinusitis (HP:0011109)1.73107537
154Wormian bones (HP:0002645)1.72237961
155Papilledema (HP:0001085)1.72209081
156Facial diplegia (HP:0001349)1.72019877
157Inflammation of the large intestine (HP:0002037)1.71852422
158Thoracolumbar scoliosis (HP:0002944)1.71562166
159Centrally nucleated skeletal muscle fibers (HP:0003687)1.71528431
160Skin ulcer (HP:0200042)1.70235678
161Increased IgE level (HP:0003212)1.69772251
162Limb-girdle muscle atrophy (HP:0003797)1.69636976

Predicted kinase interactions (KEA)

RankGene SetZ-score
1MAP4K14.10676280
2RIPK43.29322759
3TRIB33.19422099
4TTN2.95358846
5EEF2K2.95198337
6PKN22.71186105
7STK102.57815393
8PRPF4B2.37990694
9JAK32.36010497
10LRRK22.27997481
11TGFBR22.27644701
12SMG12.20680946
13TNK22.16889426
14MAP3K102.16239867
15SIK32.15352058
16ZAP702.14907747
17ERN12.09024166
18KIT2.07031843
19TXK1.98237454
20MAP2K31.96605818
21TYK21.82530163
22FES1.71333603
23ITK1.67217482
24STK241.63410056
25FGFR41.60795533
26FLT31.59591298
27BTK1.56437349
28TIE11.55700331
29JAK11.53127383
30MARK21.50298560
31TEC1.48269233
32RPS6KA41.46668955
33CSF1R1.45293464
34KDR1.44385351
35TBK11.43569403
36PRKD21.43319422
37FGFR31.40947134
38RIPK11.39883173
39TGFBR11.33697756
40EPHB11.33536022
41GRK61.29929926
42TRPM71.27649808
43MAP3K31.26235423
44PTK61.25125408
45IKBKE1.23899254
46CDK121.20406512
47MAP3K61.19341803
48KSR21.19104582
49BMX1.19034195
50TESK11.18464320
51MAP3K111.17400960
52STK381.17163742
53NLK1.16738661
54HCK1.14400782
55CSK1.12086630
56MAPKAPK31.11434689
57EPHA21.07463669
58LCK1.04526076
59BLK1.03019227
60DYRK1B1.01616031
61PAK41.01352300
62SIK11.00413317
63SYK0.99446109
64MAP3K10.96407294
65FGR0.96273835
66TESK20.95647349
67DMPK0.95071513
68IRAK40.93896214
69DDR20.93537229
70PTK2B0.91951615
71CDC42BPA0.91901419
72MAP3K70.84795315
73RPS6KB20.83471659
74EPHB20.83003547
75CLK10.82449584
76PIM10.80845568
77MAP3K140.80810689
78MAP2K20.80628294
79MARK30.78525911
80YES10.77420074
81HIPK20.76699096
82PDGFRB0.76560554
83PDPK10.76355658
84CDK60.75919256
85TAOK10.75051365
86MAPK70.74931306
87PIK3CG0.74849525
88RPS6KA20.74795775
89ILK0.74494533
90ICK0.70924079
91PDGFRA0.70008339
92STK30.69003307
93MAP3K80.66891520
94TAOK20.66203242
95PDK10.65275329
96MAPK120.64885102
97FYN0.64761069
98IKBKB0.64244435
99CAMKK10.63395710
100CHUK0.62597971
101CDK40.61945056
102PIM20.61222018
103SGK30.60311403
104EPHA30.59925784
105NEK90.59263689
106MYLK0.53090474
107MATK0.52713301
108JAK20.51492056
109PRKCH0.51478710
110LYN0.50992460
111RPS6KA60.50134449
112ROCK20.49792910
113MAP3K130.48934871
114IRAK10.48357628
115PAK20.47966237
116SIK20.47145776
117MTOR0.46741490
118OBSCN0.46737640
119STK40.46332238
120IRAK20.43957742
121PRKG20.43624564
122KSR10.43189772
123MST40.42609645
124PRKD30.42265118
125FGFR10.42168269
126CDK190.42068280
127MAPKAPK20.41456137
128NME20.40226242
129MOS0.39852531
130RPS6KL10.38600649
131RPS6KC10.38600649
132PRKD10.38338107
133NEK20.37628356
134SCYL20.37266346
135MAPK40.36964899
136CDK90.36459786
137TYRO30.35454419
138BRD40.35208972
139MAPK150.35085675
140PTK20.33594292
141RET0.32570822
142PRKCQ0.32284422

Predicted pathways (KEGG)

RankGene SetZ-score
1Primary immunodeficiency_Homo sapiens_hsa053403.06891793
2B cell receptor signaling pathway_Homo sapiens_hsa046622.14014107
3Leishmaniasis_Homo sapiens_hsa051402.06239233
4Osteoclast differentiation_Homo sapiens_hsa043801.86833142
5Viral myocarditis_Homo sapiens_hsa054161.85862893
6Leukocyte transendothelial migration_Homo sapiens_hsa046701.85130962
7T cell receptor signaling pathway_Homo sapiens_hsa046601.79793451
8Antigen processing and presentation_Homo sapiens_hsa046121.79777906
9Measles_Homo sapiens_hsa051621.79601646
10Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005321.78813872
11Hematopoietic cell lineage_Homo sapiens_hsa046401.76698401
12ECM-receptor interaction_Homo sapiens_hsa045121.72533982
13Inflammatory bowel disease (IBD)_Homo sapiens_hsa053211.66315873
14NF-kappa B signaling pathway_Homo sapiens_hsa040641.65384422
15Toxoplasmosis_Homo sapiens_hsa051451.64543612
16Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046501.63158729
17Chronic myeloid leukemia_Homo sapiens_hsa052201.60033320
18AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049331.59690809
19Bacterial invasion of epithelial cells_Homo sapiens_hsa051001.59536541
20Focal adhesion_Homo sapiens_hsa045101.56243242
21Platelet activation_Homo sapiens_hsa046111.53250833
22Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046661.52857751
23Acute myeloid leukemia_Homo sapiens_hsa052211.46951412
24Small cell lung cancer_Homo sapiens_hsa052221.40631993
25Shigellosis_Homo sapiens_hsa051311.40421078
26Pancreatic cancer_Homo sapiens_hsa052121.37274717
27Jak-STAT signaling pathway_Homo sapiens_hsa046301.34720894
28Malaria_Homo sapiens_hsa051441.31843211
29Herpes simplex infection_Homo sapiens_hsa051681.31616916
30Hepatitis B_Homo sapiens_hsa051611.27777563
31Butirosin and neomycin biosynthesis_Homo sapiens_hsa005241.26201349
32Fc epsilon RI signaling pathway_Homo sapiens_hsa046641.24508506
33Toll-like receptor signaling pathway_Homo sapiens_hsa046201.24410593
34Intestinal immune network for IgA production_Homo sapiens_hsa046721.23688125
35Phospholipase D signaling pathway_Homo sapiens_hsa040721.23026485
36HTLV-I infection_Homo sapiens_hsa051661.20674012
37Graft-versus-host disease_Homo sapiens_hsa053321.19866024
38Apoptosis_Homo sapiens_hsa042101.17826357
39Adherens junction_Homo sapiens_hsa045201.17745506
40Proteoglycans in cancer_Homo sapiens_hsa052051.15718598
41Influenza A_Homo sapiens_hsa051641.15213943
42Chagas disease (American trypanosomiasis)_Homo sapiens_hsa051421.14897863
43Staphylococcus aureus infection_Homo sapiens_hsa051501.12787386
44Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054101.11877342
45Notch signaling pathway_Homo sapiens_hsa043301.10203590
46TNF signaling pathway_Homo sapiens_hsa046681.08072365
47RIG-I-like receptor signaling pathway_Homo sapiens_hsa046221.07840196
48Neurotrophin signaling pathway_Homo sapiens_hsa047221.07517667
49Autoimmune thyroid disease_Homo sapiens_hsa053201.06961562
50* Choline metabolism in cancer_Homo sapiens_hsa052311.03383374
51Dilated cardiomyopathy_Homo sapiens_hsa054141.03340343
52Transcriptional misregulation in cancer_Homo sapiens_hsa052021.03142563
53VEGF signaling pathway_Homo sapiens_hsa043701.01189992
54Pathogenic Escherichia coli infection_Homo sapiens_hsa051301.00888229
55Cell adhesion molecules (CAMs)_Homo sapiens_hsa045141.00857244
56Colorectal cancer_Homo sapiens_hsa052100.98941591
57Legionellosis_Homo sapiens_hsa051340.96850314
58Phagosome_Homo sapiens_hsa041450.96716801
59Phosphatidylinositol signaling system_Homo sapiens_hsa040700.96413742
60NOD-like receptor signaling pathway_Homo sapiens_hsa046210.96285744
61Chemokine signaling pathway_Homo sapiens_hsa040620.96102127
62Tuberculosis_Homo sapiens_hsa051520.93974183
63Regulation of actin cytoskeleton_Homo sapiens_hsa048100.93783931
64Viral carcinogenesis_Homo sapiens_hsa052030.92444983
65Inositol phosphate metabolism_Homo sapiens_hsa005620.92091793
66Pertussis_Homo sapiens_hsa051330.91783667
67Salmonella infection_Homo sapiens_hsa051320.91546780
68Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054120.90474172
69Amoebiasis_Homo sapiens_hsa051460.89740288
70Other glycan degradation_Homo sapiens_hsa005110.88788359
71Non-small cell lung cancer_Homo sapiens_hsa052230.88290703
72ErbB signaling pathway_Homo sapiens_hsa040120.88234015
73MicroRNAs in cancer_Homo sapiens_hsa052060.87834365
74Sphingolipid signaling pathway_Homo sapiens_hsa040710.85434605
75Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.83311071
76Glioma_Homo sapiens_hsa052140.81884810
77HIF-1 signaling pathway_Homo sapiens_hsa040660.81675499
78GnRH signaling pathway_Homo sapiens_hsa049120.80983265
79p53 signaling pathway_Homo sapiens_hsa041150.80960687
80Epstein-Barr virus infection_Homo sapiens_hsa051690.80014637
81Insulin signaling pathway_Homo sapiens_hsa049100.79359984
82PI3K-Akt signaling pathway_Homo sapiens_hsa041510.79078083
83Insulin resistance_Homo sapiens_hsa049310.78723314
84Non-homologous end-joining_Homo sapiens_hsa034500.78666534
85Thyroid cancer_Homo sapiens_hsa052160.78142950
86Hepatitis C_Homo sapiens_hsa051600.77847293
87Estrogen signaling pathway_Homo sapiens_hsa049150.77193348
88Pathways in cancer_Homo sapiens_hsa052000.76940511
89Cytokine-cytokine receptor interaction_Homo sapiens_hsa040600.76912088
90Base excision repair_Homo sapiens_hsa034100.72643327
91DNA replication_Homo sapiens_hsa030300.72183700
92mTOR signaling pathway_Homo sapiens_hsa041500.71278958
93Prolactin signaling pathway_Homo sapiens_hsa049170.70815349
94Thyroid hormone signaling pathway_Homo sapiens_hsa049190.69459684
95Protein digestion and absorption_Homo sapiens_hsa049740.68434689
96Vasopressin-regulated water reabsorption_Homo sapiens_hsa049620.68385021
97Cytosolic DNA-sensing pathway_Homo sapiens_hsa046230.68035074
98Rap1 signaling pathway_Homo sapiens_hsa040150.67499405
99MAPK signaling pathway_Homo sapiens_hsa040100.67227855
100Ras signaling pathway_Homo sapiens_hsa040140.66585063
101FoxO signaling pathway_Homo sapiens_hsa040680.65934736
102Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.65844401
103Axon guidance_Homo sapiens_hsa043600.65366026
104Prostate cancer_Homo sapiens_hsa052150.64749031
105Endometrial cancer_Homo sapiens_hsa052130.64614993
106Endocytosis_Homo sapiens_hsa041440.63320484
107Melanogenesis_Homo sapiens_hsa049160.63197824
108Longevity regulating pathway - mammal_Homo sapiens_hsa042110.63154581
109TGF-beta signaling pathway_Homo sapiens_hsa043500.62805037
110Glycosaminoglycan degradation_Homo sapiens_hsa005310.62382300
111Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049610.62196542
112Central carbon metabolism in cancer_Homo sapiens_hsa052300.59555015
113Renal cell carcinoma_Homo sapiens_hsa052110.58232558
114Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047500.58216669
115Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.58202995
116Glycerophospholipid metabolism_Homo sapiens_hsa005640.55942054
117Cell cycle_Homo sapiens_hsa041100.54023194
118Adipocytokine signaling pathway_Homo sapiens_hsa049200.53003265
119Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.51935474
120Lysine degradation_Homo sapiens_hsa003100.51571158
121Allograft rejection_Homo sapiens_hsa053300.50385302
122Lysosome_Homo sapiens_hsa041420.50078860
123Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.49722739
124Bladder cancer_Homo sapiens_hsa052190.49429140
125Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.49222379
126N-Glycan biosynthesis_Homo sapiens_hsa005100.46582717

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