SLC38A2

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1notochord development (GO:0030903)4.64535451
2cell adhesion mediated by integrin (GO:0033627)4.62216113
3skin morphogenesis (GO:0043589)4.48503303
4desmosome organization (GO:0002934)4.19154799
5lymph vessel development (GO:0001945)4.05313060
6regulation of MHC class I biosynthetic process (GO:0045343)3.84899999
7COPII vesicle coating (GO:0048208)3.72313246
8cell proliferation involved in kidney development (GO:0072111)3.71310461
9Golgi transport vesicle coating (GO:0048200)3.67139446
10COPI coating of Golgi vesicle (GO:0048205)3.67139446
11bone trabecula formation (GO:0060346)3.65852278
12positive regulation of peptidyl-serine phosphorylation of STAT protein (GO:0033141)3.65537665
13regulation of peptidyl-serine phosphorylation of STAT protein (GO:0033139)3.65537665
14cell-substrate junction assembly (GO:0007044)3.65004246
15polyketide metabolic process (GO:0030638)3.61731871
16doxorubicin metabolic process (GO:0044598)3.61731871
17daunorubicin metabolic process (GO:0044597)3.61731871
18nuclear pore complex assembly (GO:0051292)3.53931375
19mesodermal cell differentiation (GO:0048333)3.46697387
20mesenchymal cell proliferation (GO:0010463)3.41706439
21retina vasculature morphogenesis in camera-type eye (GO:0061299)3.36304059
22regulation of branching involved in prostate gland morphogenesis (GO:0060687)3.32710858
23mammary gland development (GO:0030879)3.30732968
24positive regulation of odontogenesis (GO:0042482)3.28179523
25endodermal cell differentiation (GO:0035987)3.27254147
26lateral sprouting from an epithelium (GO:0060601)3.25966443
27maintenance of protein localization in endoplasmic reticulum (GO:0035437)3.24265868
28somite rostral/caudal axis specification (GO:0032525)3.23984684
29hemidesmosome assembly (GO:0031581)3.22936589
30paraxial mesoderm development (GO:0048339)3.20814769
31regulation of odontogenesis of dentin-containing tooth (GO:0042487)3.16067440
32cell migration involved in sprouting angiogenesis (GO:0002042)3.15669783
33establishment of endothelial barrier (GO:0061028)3.15656366
34negative regulation of intracellular estrogen receptor signaling pathway (GO:0033147)3.13723045
35negative regulation of DNA repair (GO:0045738)3.13046122
36negative regulation of fibrinolysis (GO:0051918)3.10492230
37regulation of transforming growth factor beta2 production (GO:0032909)3.09427436
38hypotonic response (GO:0006971)3.07372156
39regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:00450913.05637396
40cell proliferation involved in metanephros development (GO:0072203)3.04609610
41lung lobe morphogenesis (GO:0060463)3.01592610
42negative regulation of epidermis development (GO:0045683)2.96893712
43endothelial cell morphogenesis (GO:0001886)2.96200139
44ventricular trabecula myocardium morphogenesis (GO:0003222)2.96122931
45negative regulation of cell fate commitment (GO:0010454)2.92969233
46hepatocyte differentiation (GO:0070365)2.89953715
47focal adhesion assembly (GO:0048041)2.89149035
48cell-substrate adherens junction assembly (GO:0007045)2.89149035
49protein retention in ER lumen (GO:0006621)2.88971783
50regulation of Wnt signaling pathway involved in heart development (GO:0003307)2.87720683
51basement membrane organization (GO:0071711)2.87671991
52atrioventricular valve morphogenesis (GO:0003181)2.87090600
53positive regulation of osteoblast proliferation (GO:0033690)2.86326304
54adherens junction assembly (GO:0034333)2.85911948
55negative regulation of protein activation cascade (GO:2000258)2.84972850
56substrate-dependent cell migration (GO:0006929)2.84475324
57definitive hemopoiesis (GO:0060216)2.83541281
58endoderm formation (GO:0001706)2.83027815
59dichotomous subdivision of an epithelial terminal unit (GO:0060600)2.81803405
60anterior/posterior axis specification, embryo (GO:0008595)2.81359641
61regulation of plasminogen activation (GO:0010755)2.80135632
62regulation of telomere maintenance via telomerase (GO:0032210)2.79817034
63axon ensheathment in central nervous system (GO:0032291)2.79130316
64central nervous system myelination (GO:0022010)2.79130316
65negative regulation of complement activation (GO:0045916)2.78895400
66positive regulation of protein import into nucleus, translocation (GO:0033160)2.78713056
67cellular protein complex localization (GO:0034629)2.78021680
68nuclear pore organization (GO:0006999)2.77326256
69cell fate commitment involved in formation of primary germ layer (GO:0060795)2.75866141
70protein hydroxylation (GO:0018126)2.75693101
71regulation of apoptotic process involved in morphogenesis (GO:1902337)2.75302043
72protein localization to endosome (GO:0036010)2.74859180
73bundle of His cell to Purkinje myocyte communication (GO:0086069)2.73838190
74positive regulation of DNA-dependent DNA replication (GO:2000105)2.73665258
75interleukin-6-mediated signaling pathway (GO:0070102)2.73164456
76ribosome assembly (GO:0042255)2.71681406
77negative regulation of chondrocyte differentiation (GO:0032331)2.69558409
78regulation of response to osmotic stress (GO:0047484)2.68774652
79nucleotide-sugar biosynthetic process (GO:0009226)2.68740265
80lymphangiogenesis (GO:0001946)2.67703037
81cartilage development involved in endochondral bone morphogenesis (GO:0060351)2.67230908
82polarized epithelial cell differentiation (GO:0030859)2.66541481
83regulation of branching involved in salivary gland morphogenesis (GO:0060693)2.66271159
84limb bud formation (GO:0060174)2.65969981
85glomerular visceral epithelial cell development (GO:0072015)2.65319349
86keratinocyte proliferation (GO:0043616)2.65146785
87branching involved in mammary gland duct morphogenesis (GO:0060444)2.65074088
88regulation of mammary gland epithelial cell proliferation (GO:0033599)2.65023971
89gap junction assembly (GO:0016264)2.64419641
90wound healing, spreading of epidermal cells (GO:0035313)2.64271457
91mammary gland epithelial cell proliferation (GO:0033598)2.63278340
92mitotic sister chromatid cohesion (GO:0007064)2.62164386
93ER overload response (GO:0006983)2.61371223
94negative regulation of keratinocyte proliferation (GO:0010839)2.61361704
95mesenchymal-epithelial cell signaling (GO:0060638)2.61198640
96pore complex assembly (GO:0046931)2.60520900
97protein localization to kinetochore (GO:0034501)2.59262128
98trabecula morphogenesis (GO:0061383)2.59079937
99substrate adhesion-dependent cell spreading (GO:0034446)2.58909274
100regulation of odontogenesis (GO:0042481)2.57987654
101negative regulation of fatty acid transport (GO:2000192)2.57733231
102smooth muscle tissue development (GO:0048745)2.55730546
103regulation of centriole replication (GO:0046599)2.55473709
104regulation of fibrinolysis (GO:0051917)2.54170005
105vesicle coating (GO:0006901)2.53363402
106negative regulation of epidermal growth factor-activated receptor activity (GO:0007175)2.53268566
107positive regulation of endothelial cell apoptotic process (GO:2000353)2.53079565
108anterior/posterior axis specification (GO:0009948)2.53000147
109negative regulation of G2/M transition of mitotic cell cycle (GO:0010972)2.51830971
110chondrocyte development (GO:0002063)2.51449042
111myelin maintenance (GO:0043217)2.49964545
112very-low-density lipoprotein particle assembly (GO:0034379)2.48474390
113extracellular matrix assembly (GO:0085029)2.47967607
114regulation of cell fate commitment (GO:0010453)2.45251194
115positive regulation of extracellular matrix organization (GO:1903055)2.44436963
116midgut development (GO:0007494)2.44304726
117maintenance of protein location in nucleus (GO:0051457)2.44235810
118SMAD protein complex assembly (GO:0007183)2.43885604
119UDP-N-acetylglucosamine metabolic process (GO:0006047)2.43691395
120endocardial cushion development (GO:0003197)2.42444328
121glomerular filtration (GO:0003094)2.42175401
122muscle organ morphogenesis (GO:0048644)2.41455239
123embryonic skeletal joint morphogenesis (GO:0060272)2.41154259
124hair follicle morphogenesis (GO:0031069)2.40679429
125protein localization to cell surface (GO:0034394)2.40339048
126regulation of translational fidelity (GO:0006450)2.40335260
127pinocytosis (GO:0006907)2.40321115
128histone H4-K12 acetylation (GO:0043983)2.39705738
129negative regulation of cell fate specification (GO:0009996)2.39447630
130renal filtration (GO:0097205)2.38560442
131pericardium development (GO:0060039)2.38345349
132collagen fibril organization (GO:0030199)2.38299570
133positive regulation of keratinocyte differentiation (GO:0045618)2.38298267
134embryonic heart tube development (GO:0035050)2.37995070
135blood vessel endothelial cell migration (GO:0043534)2.37455188
136ER-nucleus signaling pathway (GO:0006984)2.35299541
137embryonic process involved in female pregnancy (GO:0060136)2.35031591
138negative regulation of myoblast differentiation (GO:0045662)2.34947958
139mRNA transcription from RNA polymerase II promoter (GO:0042789)2.34511847
140peptidyl-proline hydroxylation (GO:0019511)2.34426938
141iron ion import (GO:0097286)2.33849075
142regulation of nuclear cell cycle DNA replication (GO:0033262)2.33765953
143endoplasmic reticulum unfolded protein response (GO:0030968)2.33727402
144histone H4-K8 acetylation (GO:0043982)2.32945572
145histone H4-K5 acetylation (GO:0043981)2.32945572
146branching involved in salivary gland morphogenesis (GO:0060445)2.32926006
147hippo signaling (GO:0035329)2.31798212
148epithelial cell differentiation involved in prostate gland development (GO:0060742)2.31669751
149response to laminar fluid shear stress (GO:0034616)2.31319472
150regulation of transforming growth factor beta production (GO:0071634)2.30413779
151activation of signaling protein activity involved in unfolded protein response (GO:0006987)2.30304909
152regulation of osteoblast proliferation (GO:0033688)2.29999327
153blood vessel maturation (GO:0001955)2.29261810
154response to follicle-stimulating hormone (GO:0032354)2.29184092
155metanephric mesenchyme development (GO:0072075)2.28661074
156heart trabecula morphogenesis (GO:0061384)2.28601141
157regulation of cell migration involved in sprouting angiogenesis (GO:0090049)2.28020427
158regulation of apoptotic cell clearance (GO:2000425)2.27510753
159negative regulation of anoikis (GO:2000811)2.27071282
160peptidyl-glutamic acid carboxylation (GO:0017187)2.26916534
161protein carboxylation (GO:0018214)2.26916534
162cardiac muscle cell proliferation (GO:0060038)2.26790878
163protein complex localization (GO:0031503)2.26700127
164heart valve morphogenesis (GO:0003179)2.26372923
165positive regulation of vasculogenesis (GO:2001214)2.25918102
166positive regulation of p38MAPK cascade (GO:1900745)2.25501487
167morphogenesis of an epithelial sheet (GO:0002011)2.25337450
168apoptotic cell clearance (GO:0043277)2.25235363
169cellular response to vitamin D (GO:0071305)2.24875898
170primitive streak formation (GO:0090009)2.24605681
171positive regulation of nuclease activity (GO:0032075)2.24323581
172interferon-gamma production (GO:0032609)2.23984060
173ventricular cardiac muscle tissue morphogenesis (GO:0055010)2.22794118
174regulation of metanephric nephron tubule epithelial cell differentiation (GO:0072307)2.22775965
175regulation of complement activation (GO:0030449)2.22678522
176lung vasculature development (GO:0060426)2.22403042
177mRNA transcription (GO:0009299)2.21628699
178regulation of endothelial cell differentiation (GO:0045601)2.21122553
179negative regulation of cell cycle G2/M phase transition (GO:1902750)2.20971486
180regulation of intracellular estrogen receptor signaling pathway (GO:0033146)2.20206379
181regulation of cardioblast differentiation (GO:0051890)2.20190362
182regulation of SMAD protein import into nucleus (GO:0060390)2.20136179
183chondrocyte proliferation (GO:0035988)2.19863679

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1TP63_17297297_ChIP-ChIP_HaCaT_Human5.91163727
2KLF5_18264089_ChIP-ChIP_MESCs_Mouse4.90539637
3KLF4_18264089_ChIP-ChIP_MESCs_Mouse4.90539637
4KLF2_18264089_ChIP-ChIP_MESCs_Mouse4.90539637
5BP1_19119308_ChIP-ChIP_Hs578T_Human4.29145601
6AR_21909140_ChIP-Seq_LNCAP_Human3.10820844
7TRIM28_21343339_ChIP-Seq_HEK293_Human3.07167140
8FOXP3_17237761_ChIP-ChIP_TREG_Mouse2.94765034
9E2F7_22180533_ChIP-Seq_HELA_Human2.81099113
10FOXM1_23109430_ChIP-Seq_U2OS_Human2.79604295
11TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse2.75342844
12WT1_19549856_ChIP-ChIP_CCG9911_Human2.72726308
13TP63_19390658_ChIP-ChIP_HaCaT_Human2.69963728
14ZNF263_19887448_ChIP-Seq_K562_Human2.63093073
15SMAD4_19686287_ChIP-ChIP_HaCaT_Human2.61988872
16NANOG_18700969_ChIP-ChIP_MESCs_Mouse2.58387057
17* HIF1A_21447827_ChIP-Seq_MCF-7_Human2.53017531
18RBPJ_22232070_ChIP-Seq_NCS_Mouse2.40314014
19TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat2.34302059
20SALL1_21062744_ChIP-ChIP_HESCs_Human2.07573958
21EP300_20729851_ChIP-Seq_FORBRAIN_MIDBRAIN_LIMB_HEART_Mouse2.06084504
22* SOX2_18358816_ChIP-ChIP_MESCs_Mouse2.06031876
23STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse2.05105439
24GATA2_21666600_ChIP-Seq_HMVEC_Human2.04438080
25TCF3_18692474_ChIP-Seq_MEFs_Mouse2.03539317
26TCF3_18692474_ChIP-Seq_MESCs_Mouse2.02102432
27NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse2.01194245
28* SALL4_18804426_ChIP-ChIP_MESCs_Mouse1.95109751
29SMAD3_22036565_ChIP-Seq_ESCs_Mouse1.92289255
30ESR1_21235772_ChIP-Seq_MCF-7_Human1.90328781
31CEBPD_23245923_ChIP-Seq_MEFs_Mouse1.85464028
32NACC1_18358816_ChIP-ChIP_MESCs_Mouse1.84212438
33PRDM5_23873026_ChIP-Seq_MEFs_Mouse1.81882104
34* KLF6_26769127_Chip-Seq_PDAC-Cell_line_Human1.79876194
35EGR1_19374776_ChIP-ChIP_THP-1_Human1.79426450
36POU5F1_16153702_ChIP-ChIP_HESCs_Human1.65403962
37ESR1_20079471_ChIP-ChIP_T-47D_Human1.65231892
38* FOXA1_26769127_Chip-Seq_PDAC-Cell_line_Human1.64080798
39ZIC3_20872845_ChIP-ChIP_MESCs_Mouse1.62557184
40* WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse1.59214715
41FOXO3_23340844_ChIP-Seq_DLD1_Human1.58125822
42* SMAD2_18955504_ChIP-ChIP_HaCaT_Human1.56640246
43* SMAD3_18955504_ChIP-ChIP_HaCaT_Human1.56640246
44TCF3_18347094_ChIP-ChIP_MESCs_Mouse1.53686406
45ZFP281_18358816_ChIP-ChIP_MESCs_Mouse1.53635601
46SOX2_18555785_ChIP-Seq_MESCs_Mouse1.53176161
47* ZNF217_24962896_ChIP-Seq_MCF-7_Human1.52720654
48ESR1_17901129_ChIP-ChIP_LIVER_Mouse1.49671053
49SMAD1_18555785_ChIP-Seq_MESCs_Mouse1.47157354
50FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human1.47049459
51* RUNX2_24764292_ChIP-Seq_MC3T3_Mouse1.45556802
52* SALL4_18804426_ChIP-ChIP_XEN_Mouse1.45122027
53CDX2_20551321_ChIP-Seq_CACO-2_Human1.43761808
54TAF7L_23326641_ChIP-Seq_C3H10T1-2_Mouse1.42332690
55* CEBPD_21427703_ChIP-Seq_3T3-L1_Mouse1.42085701
56* ATF3_27146783_Chip-Seq_COLON_Human1.39171587
57CLOCK_20551151_ChIP-Seq_293T_Human1.38933610
58ESR2_21235772_ChIP-Seq_MCF-7_Human1.37712183
59* BRD4_25478319_ChIP-Seq_HGPS_Human1.36863499
60NANOG_18347094_ChIP-ChIP_MESCs_Mouse1.35598494
61CJUN_26792858_Chip-Seq_BT549_Human1.35105076
62STAT6_21828071_ChIP-Seq_BEAS2B_Human1.33265575
63HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse1.32278143
64* TCF3_18467660_ChIP-ChIP_MESCs_Mouse1.32149910
65MYC_18555785_ChIP-Seq_MESCs_Mouse1.31248325
66* KLF4_26769127_Chip-Seq_PDAC-Cell_line_Human1.28579012
67* P300_27058665_Chip-Seq_ZR-75-30cells_Human1.26474867
68* KDM5B_21448134_ChIP-Seq_MESCs_Mouse1.25777244
69* SMARCA4_20176728_ChIP-ChIP_TSCs_Mouse1.25676529
70* NELFA_20434984_ChIP-Seq_ESCs_Mouse1.25001884
71SCL_19346495_ChIP-Seq_HPC-7_Human1.24191184
72E2F4_17652178_ChIP-ChIP_JURKAT_Human1.23675736
73* AHR_22903824_ChIP-Seq_MCF-7_Human1.23544277
74ESR1_22446102_ChIP-Seq_UTERUS_Mouse1.22509521
75GLI1_17442700_ChIP-ChIP_MESCs_Mouse1.22091028
76CTNNB1_20460455_ChIP-Seq_HCT116_Human1.20890950
77NKX2-5_21415370_ChIP-Seq_HL-1_Mouse1.20673099
78ZFX_18555785_ChIP-Seq_MESCs_Mouse1.20262723
79EP300_21415370_ChIP-Seq_HL-1_Mouse1.18923532
80* SOX17_20123909_ChIP-Seq_XEN_Mouse1.18798119
81SMAD_19615063_ChIP-ChIP_OVARY_Human1.17775366
82FOXA1_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human1.17717529
83STAT3_24763339_ChIP-Seq_IMN-ESCs_Mouse1.17303876
84TP53_16413492_ChIP-PET_HCT116_Human1.16709339
85SOX9_24532713_ChIP-Seq_HFSC_Mouse1.15122764
86FOXM1_26100407_CHIP-SEQ_Hek293_flp-in_Human1.14948210
87* FOXA2_19822575_ChIP-Seq_HepG2_Human1.14559249
88RARG_19884340_ChIP-ChIP_MEFs_Mouse1.14269830
89* PPAR_26484153_Chip-Seq_NCI-H1993_Human1.13553520
90MYCN_18555785_ChIP-Seq_MESCs_Mouse1.13014517
91NRF2_20460467_ChIP-Seq_MEFs_Mouse1.12882713
92NFE2L2_20460467_ChIP-Seq_MEFs_Mouse1.12882713
93* POU5F1_18700969_ChIP-ChIP_MESCs_Mouse1.12741598
94POU5F1_18347094_ChIP-ChIP_MESCs_Mouse1.12207476
95NANOG_16153702_ChIP-ChIP_HESCs_Human1.11562926
96* ZFP281_27345836_Chip-Seq_ESCs_Mouse1.11479970
97* ELF3_26769127_Chip-Seq_PDAC-Cell_line_Human1.11355451
98ISL1_27105846_Chip-Seq_CPCs_Mouse1.10729861
99EOMES_20176728_ChIP-ChIP_TSCs_Mouse1.10357504
100HOXD13_18407260_ChIP-ChIP_DEVELOPING-LIMBS_Mouse1.10179040
101* PRDM14_21183938_ChIP-Seq_MESCs_Mouse1.09988239
102* TCFAP2C_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse1.07609013
103BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse1.07379217
104* TCF21_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human1.07332941
105* CHD1_26751641_Chip-Seq_LNCaP_Human1.06880471
106SOX2_27498859_Chip-Seq_STOMACH_Mouse1.06278894
107NR1I2_20693526_ChIP-Seq_LIVER_Mouse1.05025954
108KLF4_18555785_ChIP-Seq_MESCs_Mouse1.04817534
109* DMRT1_23473982_ChIP-Seq_TESTES_Mouse1.04070056
110* FOXM1_26456572_ChIP-Seq_MCF-7_Human1.02053159
111E2F1_21310950_ChIP-Seq_MCF-7_Human1.01936166
112* ELK3_25401928_ChIP-Seq_HUVEC_Human0.99762186
113GATA6_25053715_ChIP-Seq_YYC3_Human0.99285093
114JUND_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human0.99018605
115* UBF1/2_26484160_Chip-Seq_HMECs_Human0.98312534
116* TBX3_20139965_ChIP-Seq_MESCs_Mouse0.97656428
117NANOG_18692474_ChIP-Seq_MEFs_Mouse0.97329676
118* TBX3_20139965_ChIP-Seq_ESCs_Mouse0.96710923
119RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human0.96226759
120TRIM28_17542650_ChIP-ChIP_NTERA2_Human0.95494846
121* ARNT_22903824_ChIP-Seq_MCF-7_Human0.95399490
122ESR1_15608294_ChIP-ChIP_MCF-7_Human0.95365175
123* HSF1_23293686_ChIP-Seq_STHDH_STRIATAL_Mouse0.95359048
124NFIB_24661679_ChIP-Seq_LUNG_Mouse0.95175090
125MEF2A_21415370_ChIP-Seq_HL-1_Mouse0.94998202
126Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse0.94062314
127RUNX_20019798_ChIP-Seq_JUKART_Human0.93820448
128ATF3_23680149_ChIP-Seq_GBM1-GSC_Human0.92526635
129ELK1_19687146_ChIP-ChIP_HELA_Human0.92269816
130PADI4_21655091_ChIP-ChIP_MCF-7_Human0.91245900
131* MYC_19079543_ChIP-ChIP_MESCs_Mouse0.90928001
132PPARD_23176727_ChIP-Seq_KERATINOCYTES_Mouse0.90651757
133* RING1B_27294783_Chip-Seq_NPCs_Mouse0.90201948
134ZFP281_18757296_ChIP-ChIP_E14_Mouse0.89825079
135NANOG_18692474_ChIP-Seq_MESCs_Mouse0.89299702
136DACH1_20351289_ChIP-Seq_MDA-MB-231_Human0.88993494
137TP53_18474530_ChIP-ChIP_U2OS_Human0.86821325
138POU5F1_16518401_ChIP-PET_MESCs_Mouse0.86269155
139TCF4_18268006_ChIP-ChIP_LS174T_Human0.86214375
140* TP53_22127205_ChIP-Seq_IMR90_Human0.86000412
141* KLF4_19030024_ChIP-ChIP_MESCs_Mouse0.85335645
142* CEBPB_21427703_ChIP-Seq_3T3-L1_Mouse0.85099417
143* SOX2_20726797_ChIP-Seq_SW620_Human0.84394988

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0004272_abnormal_basement_membrane2.79276188
2MP0010368_abnormal_lymphatic_system2.71563734
3MP0010030_abnormal_orbit_morphology2.70221284
4MP0005503_abnormal_tendon_morphology2.67268368
5MP0006054_spinal_hemorrhage2.58698088
6MP0005623_abnormal_meninges_morphology2.55162102
7MP0001879_abnormal_lymphatic_vessel2.39239548
8MP0008438_abnormal_cutaneous_collagen2.39155571
9MP0003705_abnormal_hypodermis_morpholog2.29693675
10MP0003122_maternal_imprinting2.18263576
11MP0000762_abnormal_tongue_morphology2.12437221
12MP0002254_reproductive_system_inflammat2.03993221
13MP0010234_abnormal_vibrissa_follicle1.97361041
14MP0003121_genomic_imprinting1.92568576
15MP0004264_abnormal_extraembryonic_tissu1.91693157
16MP0003950_abnormal_plasma_membrane1.88756213
17MP0002877_abnormal_melanocyte_morpholog1.87729319
18MP0000383_abnormal_hair_follicle1.84450801
19MP0005508_abnormal_skeleton_morphology1.81091790
20MP0003279_aneurysm1.80861352
21MP0008057_abnormal_DNA_replication1.79599891
22MP0000566_synostosis1.77300187
23MP0009250_abnormal_appendicular_skeleto1.72529510
24MP0010352_gastrointestinal_tract_polyps1.71552961
25MP0005076_abnormal_cell_differentiation1.70926976
26MP0009780_abnormal_chondrocyte_physiolo1.68887670
27MP0003566_abnormal_cell_adhesion1.60632615
28MP0004233_abnormal_muscle_weight1.57664335
29MP0005275_abnormal_skin_tensile1.57548128
30MP0003890_abnormal_embryonic-extraembry1.57238954
31MP0001915_intracranial_hemorrhage1.56693456
32MP0003828_pulmonary_edema1.55751533
33MP0002796_impaired_skin_barrier1.53659821
34MP0004134_abnormal_chest_morphology1.53016929
35MP0010678_abnormal_skin_adnexa1.52816182
36MP0002932_abnormal_joint_morphology1.52780708
37MP0000579_abnormal_nail_morphology1.50678939
38MP0005409_darkened_coat_color1.47677949
39MP0003755_abnormal_palate_morphology1.47423909
40MP0002925_abnormal_cardiovascular_devel1.47027732
41MP0000767_abnormal_smooth_muscle1.46329846
42MP0003567_abnormal_fetal_cardiomyocyte1.45619670
43MP0003937_abnormal_limbs/digits/tail_de1.43762862
44MP0003385_abnormal_body_wall1.38876469
45MP0005023_abnormal_wound_healing1.37529911
46MP0004957_abnormal_blastocyst_morpholog1.36210408
47MP0003935_abnormal_craniofacial_develop1.35968814
48MP0001299_abnormal_eye_distance/1.35292959
49MP0003091_abnormal_cell_migration1.33961271
50MP0002896_abnormal_bone_mineralization1.32377021
51MP0003984_embryonic_growth_retardation1.32356204
52MP0002088_abnormal_embryonic_growth/wei1.31994643
53MP0000049_abnormal_middle_ear1.30491484
54MP0002233_abnormal_nose_morphology1.28983871
55MP0000537_abnormal_urethra_morphology1.28827031
56MP0001849_ear_inflammation1.28795743
57MP0002108_abnormal_muscle_morphology1.27548163
58MP0000432_abnormal_head_morphology1.27026670
59MP0005501_abnormal_skin_physiology1.24348904
60MP0001672_abnormal_embryogenesis/_devel1.22609403
61MP0005380_embryogenesis_phenotype1.22609403
62MP0003943_abnormal_hepatobiliary_system1.22004306
63MP0002282_abnormal_trachea_morphology1.20345075
64MP0000163_abnormal_cartilage_morphology1.20038655
65MP0000733_abnormal_muscle_development1.18706462
66MP0004883_abnormal_blood_vessel1.17870615
67MP0004185_abnormal_adipocyte_glucose1.16406144
68MP0000003_abnormal_adipose_tissue1.16086564
69MP0001293_anophthalmia1.15698622
70MP0002127_abnormal_cardiovascular_syste1.15345101
71MP0001661_extended_life_span1.14881555
72MP0003941_abnormal_skin_development1.14656826
73MP0004197_abnormal_fetal_growth/weight/1.13408790
74MP0002060_abnormal_skin_morphology1.11874051
75MP0000428_abnormal_craniofacial_morphol1.10935006
76MP0001243_abnormal_dermal_layer1.09978975
77MP0003453_abnormal_keratinocyte_physiol1.09474711
78MP0002697_abnormal_eye_size1.08882626
79MP0002092_abnormal_eye_morphology1.08749630
80MP0009384_cardiac_valve_regurgitation1.08407103
81MP0001730_embryonic_growth_arrest1.08310564
82MP0002116_abnormal_craniofacial_bone1.07907286
83MP0003111_abnormal_nucleus_morphology1.06823915
84MP0008932_abnormal_embryonic_tissue1.06710771
85MP0002086_abnormal_extraembryonic_tissu1.06149821
86MP0008775_abnormal_heart_ventricle1.05684266
87MP0005257_abnormal_intraocular_pressure1.05648690
88MP0003942_abnormal_urinary_system1.05102464
89MP0003787_abnormal_imprinting1.05082132
90MP0009697_abnormal_copulation1.04172452
91MP0000749_muscle_degeneration1.04009416
92MP0003123_paternal_imprinting1.03657585
93MP0001216_abnormal_epidermal_layer1.02905846
94MP0002109_abnormal_limb_morphology1.02772165
95MP0000467_abnormal_esophagus_morphology1.02193156
96MP0002098_abnormal_vibrissa_morphology1.01528044
97MP0000013_abnormal_adipose_tissue1.00494398
98MP0002114_abnormal_axial_skeleton1.00098864
99MP0001958_emphysema0.98359516
100MP0001614_abnormal_blood_vessel0.97440989
101MP0008007_abnormal_cellular_replicative0.97161193
102MP0001270_distended_abdomen0.96957104
103MP0010630_abnormal_cardiac_muscle0.96907977
104MP0009053_abnormal_anal_canal0.95414153
105MP0001697_abnormal_embryo_size0.94378170
106MP0003115_abnormal_respiratory_system0.94333212
107MP0002089_abnormal_postnatal_growth/wei0.94038767
108MP0002249_abnormal_larynx_morphology0.93670228
109MP0001286_abnormal_eye_development0.92399480
110MP0000534_abnormal_ureter_morphology0.92140356
111MP0000516_abnormal_urinary_system0.90933287
112MP0005367_renal/urinary_system_phenotyp0.90933287
113MP0005621_abnormal_cell_physiology0.90748504
114MP0002085_abnormal_embryonic_tissue0.89511982
115MP0000627_abnormal_mammary_gland0.88575452
116MP0005499_abnormal_olfactory_system0.88572286
117MP0005394_taste/olfaction_phenotype0.88572286
118MP0002332_abnormal_exercise_endurance0.88040240
119MP0002113_abnormal_skeleton_development0.87880491
120MP0003191_abnormal_cellular_cholesterol0.87791970
121MP0002084_abnormal_developmental_patter0.87381852
122MP0001348_abnormal_lacrimal_gland0.86710678
123MP0003868_abnormal_feces_composition0.86254114
124MP0000647_abnormal_sebaceous_gland0.85626795
125MP0005248_abnormal_Harderian_gland0.85475242
126MP0000350_abnormal_cell_proliferation0.85446708
127MP0002111_abnormal_tail_morphology0.85121206
128MP0002128_abnormal_blood_circulation0.84993097
129MP0005197_abnormal_uvea_morphology0.84861382
130MP0002080_prenatal_lethality0.84689655
131MP0002009_preneoplasia0.83487447
132MP0001784_abnormal_fluid_regulation0.83140321
133MP0000266_abnormal_heart_morphology0.82888861
134MP0006138_congestive_heart_failure0.82248776
135MP0003077_abnormal_cell_cycle0.80549499
136MP0010094_abnormal_chromosome_stability0.80395443
137MP0005360_urolithiasis0.80264683
138MP0009672_abnormal_birth_weight0.78188104
139MP0010771_integument_phenotype0.77057025

Predicted human phenotypes

RankGene SetZ-score
1Hepatoblastoma (HP:0002884)3.95690899
2Bilateral microphthalmos (HP:0007633)3.62088603
3Arterial tortuosity (HP:0005116)3.60556600
4Aortic dissection (HP:0002647)3.23779248
5Premature rupture of membranes (HP:0001788)3.01907476
6Increased connective tissue (HP:0009025)2.87244766
7Asymmetry of the thorax (HP:0001555)2.86337829
8Deep venous thrombosis (HP:0002625)2.86033608
9Abnormality of the distal phalanx of the thumb (HP:0009617)2.73136441
10Epiphyseal dysplasia (HP:0002656)2.63752212
11Abnormality of carpal bone ossification (HP:0006257)2.61186488
12Cardiovascular calcification (HP:0011915)2.51851053
13Cupped ribs (HP:0000887)2.51806038
14Follicular hyperkeratosis (HP:0007502)2.47264899
15Abnormality of the phalanges of the 2nd finger (HP:0009541)2.47109778
16Soft skin (HP:0000977)2.46000787
17Hypoplastic ischia (HP:0003175)2.44037492
18Ankle contracture (HP:0006466)2.41498803
19Nephroblastoma (Wilms tumor) (HP:0002667)2.40094004
20Mesomelia (HP:0003027)2.39335300
21Fragile skin (HP:0001030)2.38552431
22Preauricular pit (HP:0004467)2.35410912
23Periauricular skin pits (HP:0100277)2.35410912
24Fused cervical vertebrae (HP:0002949)2.32100743
25Abnormality of the ischium (HP:0003174)2.31848213
26Hypochromic microcytic anemia (HP:0004840)2.31705213
27Pterygium (HP:0001059)2.30927220
28Embryonal renal neoplasm (HP:0011794)2.30465538
29Abnormality of the acetabulum (HP:0003170)2.30243997
30Irregular epiphyses (HP:0010582)2.29949977
31Right ventricular cardiomyopathy (HP:0011663)2.29401579
32Pancreatic islet-cell hyperplasia (HP:0004510)2.27409366
33Natal tooth (HP:0000695)2.26906926
34Bladder diverticulum (HP:0000015)2.25756954
35Abnormal ossification of hand bones (HP:0005921)2.25664738
36Osteolytic defects of the hand bones (HP:0009699)2.25173458
37Osteolytic defects of the phalanges of the hand (HP:0009771)2.25173458
38Vitreoretinal degeneration (HP:0000655)2.24687843
39Small epiphyses (HP:0010585)2.24622728
40Rib fusion (HP:0000902)2.24146803
41Flat capital femoral epiphysis (HP:0003370)2.21343816
42Onycholysis (HP:0001806)2.19971281
43Ankyloglossia (HP:0010296)2.19824035
44Aortic aneurysm (HP:0004942)2.17141504
45Subacute progressive viral hepatitis (HP:0006572)2.16152512
46Vertebral arch anomaly (HP:0008438)2.14743656
47Vertebral compression fractures (HP:0002953)2.14578129
48Elbow flexion contracture (HP:0002987)2.14088655
49Protrusio acetabuli (HP:0003179)2.11703610
50Distal lower limb muscle weakness (HP:0009053)2.10616889
51Ulnar bowing (HP:0003031)2.10270136
52Absent frontal sinuses (HP:0002688)2.10076179
53Abnormality of dentin (HP:0010299)2.09810149
54Atrophic scars (HP:0001075)2.09693380
55Mitral valve prolapse (HP:0001634)2.09313089
56Vascular calcification (HP:0004934)2.08119318
57Diastasis recti (HP:0001540)2.08012470
58Short middle phalanx of finger (HP:0005819)2.07276860
59Partial duplication of thumb phalanx (HP:0009944)2.06464119
60Abnormal lung lobation (HP:0002101)2.06388132
61Advanced eruption of teeth (HP:0006288)2.04954811
62Mitral stenosis (HP:0001718)2.03288242
63Abnormal vertebral ossification (HP:0100569)2.01918075
64Neonatal short-limb short stature (HP:0008921)2.01834965
65Milia (HP:0001056)2.00767879
66Short humerus (HP:0005792)2.00597575
67Blue sclerae (HP:0000592)2.00493224
68Short 4th metacarpal (HP:0010044)1.99782221
69Aplasia/Hypoplasia of the 4th metacarpal (HP:0010042)1.99782221
70Abnormal hand bone ossification (HP:0010660)1.99608890
71Hypoplastic scapulae (HP:0000882)1.99173533
72Aplasia/Hypoplasia of the scapulae (HP:0006713)1.99173533
73Selective tooth agenesis (HP:0001592)1.98272637
74Metaphyseal cupping (HP:0003021)1.97298061
75Coronal craniosynostosis (HP:0004440)1.97246761
76Abnormality of oral frenula (HP:0000190)1.96983909
77Spondylolisthesis (HP:0003302)1.96895874
78Abnormal delivery (HP:0001787)1.96877366
79Abnormality of the calcaneus (HP:0008364)1.96248247
80Flat acetabular roof (HP:0003180)1.96209155
81Abnormality of the common coagulation pathway (HP:0010990)1.96053426
82Glossoptosis (HP:0000162)1.95287830
83Spinal rigidity (HP:0003306)1.95109008
84Stomach cancer (HP:0012126)1.95096603
85Short nail (HP:0001799)1.94812612
86Abnormality of the 2nd finger (HP:0004100)1.94526877
87Renal duplication (HP:0000075)1.94180757
88Abnormality of the pubic bones (HP:0003172)1.94007807
89Partial duplication of the phalanx of hand (HP:0009999)1.93821507
90Cerebral aneurysm (HP:0004944)1.93785166
91Vascular tortuosity (HP:0004948)1.93355168
92Mitral regurgitation (HP:0001653)1.93050493
93Short 5th finger (HP:0009237)1.92171798
94Broad metatarsal (HP:0001783)1.92155440
95Shallow orbits (HP:0000586)1.92036981
96Mild short stature (HP:0003502)1.91142297
97Abnormality of the intrinsic pathway (HP:0010989)1.90070816
98Skin pits (HP:0100276)1.89577666
99Broad thumb (HP:0011304)1.89516980
100Spinal cord lesions (HP:0100561)1.88849479
101Syringomyelia (HP:0003396)1.88849479
102Wormian bones (HP:0002645)1.87973355
103Overgrowth (HP:0001548)1.86500120
104Wide anterior fontanel (HP:0000260)1.86015216
105Abnormal foot bone ossification (HP:0010675)1.85484114
106Deviation of the thumb (HP:0009603)1.84801020
107Abnormality of the nasal septum (HP:0000419)1.83914219
108Delayed closure of the anterior fontanelle (HP:0001476)1.83631788
109Aplasia/Hypoplasia of the pubic bone (HP:0009104)1.83131302
110Distal lower limb amyotrophy (HP:0008944)1.81242765
111Termporal pattern (HP:0011008)1.80701588
112Insidious onset (HP:0003587)1.80701588
113Aplasia/hypoplasia of the humerus (HP:0006507)1.80245992
114Back pain (HP:0003418)1.79981857
115Premature skin wrinkling (HP:0100678)1.79884844
116Abnormal tarsal ossification (HP:0008369)1.79536264
117Upper limb muscle weakness (HP:0003484)1.78816218
118Microglossia (HP:0000171)1.78514789
119Hypoplastic labia majora (HP:0000059)1.78193057
120Adrenal hypoplasia (HP:0000835)1.77569169
121Broad phalanx (HP:0006009)1.77558013
122Absent eyelashes (HP:0000561)1.75783229
123Esophageal atresia (HP:0002032)1.75572310
124Sparse lateral eyebrow (HP:0005338)1.75435788
125Mildly elevated creatine phosphokinase (HP:0008180)1.74915658
126Cervical subluxation (HP:0003308)1.74884540
127Broad palm (HP:0001169)1.74764428
128Nasolacrimal duct obstruction (HP:0000579)1.74761188
129Dilatation of the ascending aorta (HP:0005111)1.74155324
130Broad long bones (HP:0005622)1.73856728
131Limited elbow extension (HP:0001377)1.73050993
132Arnold-Chiari malformation (HP:0002308)1.70562082
133Entropion (HP:0000621)1.70314789
134Tracheal stenosis (HP:0002777)1.69138697
135Aplasia/Hypoplasia of the middle phalanges of the hand (HP:0009843)1.69060395
136Papillary thyroid carcinoma (HP:0002895)1.68449431
137Aplasia/Hypoplasia of the phalanges of the 5th finger (HP:0009376)1.68021282
138Alopecia of scalp (HP:0002293)1.67813942
139Volvulus (HP:0002580)1.67141126
140Protruding ear (HP:0000411)1.67014446
141Joint laxity (HP:0001388)1.67010772
142Stillbirth (HP:0003826)1.66138544
143Biconcave vertebral bodies (HP:0004586)1.65662860
144Aplasia/Hypoplasia of the 5th finger (HP:0006262)1.65381186
145Abnormality of the middle phalanges of the hand (HP:0009833)1.65178830
146Deep philtrum (HP:0002002)1.64994651
147Preaxial foot polydactyly (HP:0001841)1.64035366
148Knee flexion contracture (HP:0006380)1.63962962
149Rhizomelia (HP:0008905)1.63962939
150Aplasia/Hypoplasia of the frontal sinuses (HP:0009119)1.63556109
151Stenosis of the external auditory canal (HP:0000402)1.63290111
152Aneurysm (HP:0002617)1.63074606
153Abnormality of the pulmonary veins (HP:0011718)1.61574431
154Abnormality of the frontal sinuses (HP:0002687)1.61499205
155Abnormality of incisor morphology (HP:0011063)1.61195003
156Broad phalanges of the hand (HP:0009768)1.61142853
157Abnormality of the phalanges of the hallux (HP:0010057)1.60936236
158Tetraparesis (HP:0002273)1.60723896
159Fragile nails (HP:0001808)1.60092411
160Abnormality of the labia majora (HP:0012881)1.59676453
161Scapular winging (HP:0003691)1.59231675
162Rectovaginal fistula (HP:0000143)1.58877102
163Rectal fistula (HP:0100590)1.58877102
164Preauricular skin tag (HP:0000384)1.58757095
165Vertebral hypoplasia (HP:0008417)1.58637681
166Aplasia/Hypoplasia of the vertebrae (HP:0008515)1.58637681
167Coxa vara (HP:0002812)1.57982038
168Plantar hyperkeratosis (HP:0007556)1.57908589
169Relative macrocephaly (HP:0004482)1.56754106
170Prolonged partial thromboplastin time (HP:0003645)1.56356599
171Delayed cranial suture closure (HP:0000270)1.56349112
172Hyperextensible skin (HP:0000974)1.55815256
173Conjugated hyperbilirubinemia (HP:0002908)1.55350849
174Thick nail (HP:0001805)1.55128502
175Overlapping toe (HP:0001845)1.54589414
176Abnormality of the epiphyses of the phalanges of the hand (HP:0005920)1.54356651

Predicted kinase interactions (KEA)

RankGene SetZ-score
1CDK125.24553004
2MST1R3.62326469
3LATS22.82074846
4TGFBR22.81568309
5TIE12.64740171
6SCYL22.43401159
7FGFR22.25567153
8ERN12.22186872
9MAPK72.20687471
10BCR2.16931578
11WNK12.11105469
12BRSK22.08093236
13EIF2AK32.00309221
14SIK31.91526425
15TGFBR11.91235960
16AKT31.89902257
17STK101.88031537
18ICK1.85193940
19GRK11.82505380
20EPHA21.78912601
21NEK91.66441258
22TRPM71.65763239
23FGFR41.64489581
24EEF2K1.61927557
25LATS11.61852746
26GRK51.61081927
27PBK1.55984205
28EIF2AK11.49914151
29NUAK11.49810407
30ZAK1.44552186
31ERBB31.44510666
32NTRK11.39434558
33EPHB11.36347476
34CSF1R1.33177994
35RIPK11.31290861
36FLT31.31151191
37MAP3K31.26678761
38PAK41.24861894
39NEK11.24552368
40NEK61.24177705
41FRK1.23221531
42FGFR31.22614674
43PDK21.22092061
44MELK1.21327035
45DDR21.20594469
46BMPR1B1.19312618
47MYLK1.18487479
48WNK41.16464867
49PRKG21.12441879
50PDGFRA1.12188061
51MET1.10539487
52LIMK11.08785609
53EPHA31.08621369
54STK391.05618018
55MAP3K141.04501168
56SMG11.04185208
57WEE11.02134584
58KDR1.01922666
59EPHB21.00133311
60TYRO30.95629334
61PKN10.95363362
62HIPK20.94122124
63TTN0.92458149
64SRPK10.91799769
65STK30.90060634
66CSNK1A1L0.89350806
67BRD40.89227821
68CAMK40.88770456
69ITK0.88239744
70MAP3K120.87895717
71TTK0.87383666
72ADRBK20.85094747
73GRK60.82534393
74YES10.82363885
75CHUK0.81714707
76PLK30.80977843
77PDGFRB0.80948442
78GSK3A0.79482919
79BRSK10.78990729
80BUB10.78372869
81GRK70.77881219
82PTK20.76534004
83MKNK10.76429191
84SIK10.76388742
85CDK70.76067639
86TAF10.75072421
87MTOR0.74924077
88NLK0.74066061
89EIF2AK20.73670512
90PTK60.73050968
91MST40.73040888
92MAPK120.71500217
93TRIB30.71236228
94MATK0.70441136
95DMPK0.69855991
96PAK20.69311958
97MAP3K20.69220379
98CLK10.69134772
99TRIM280.68007357
100MAPKAPK20.67947983
101RPS6KB20.67274362
102CDK80.64995503
103PKN20.60187368
104MOS0.58940922
105NEK20.56791841
106CAMK1G0.56663283
107PIK3CA0.56607315
108INSRR0.54598348
109CDK60.54480603
110STK380.53267636
111RPS6KA40.51775114
112ERBB40.50070334
113ROCK20.49390160
114ERBB20.49183038
115IGF1R0.49094714
116MAP3K100.48509379
117MARK20.48417101
118TSSK60.48183278
119MAP2K30.47947613
120MAPK10.47825263
121SGK2230.46878865
122SGK4940.46878865
123IRAK30.46659619
124CAMK1D0.46109334
125STK240.45872291
126PIM10.45181227
127FER0.44427488
128ATM0.43284886
129FGFR10.41973916
130BMX0.40897886
131STK38L0.40808306
132CHEK10.40560207
133RPS6KB10.40138697
134CDK90.39472130
135CHEK20.38959856
136PRKD10.38823354
137CDC70.38277935
138INSR0.38083206
139RAF10.37705266
140MKNK20.37379205
141MAP3K70.37142940
142MAP3K60.36464284
143AURKB0.34134955
144PLK10.31392155
145MAP3K90.28185440
146SGK30.27640396

Predicted pathways (KEGG)

RankGene SetZ-score
1ECM-receptor interaction_Homo sapiens_hsa045122.78494030
2Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006032.46137517
3Basal cell carcinoma_Homo sapiens_hsa052172.40418982
4Hippo signaling pathway_Homo sapiens_hsa043902.11804431
5Adherens junction_Homo sapiens_hsa045202.09616736
6TGF-beta signaling pathway_Homo sapiens_hsa043502.04957783
7Focal adhesion_Homo sapiens_hsa045102.00365227
8Complement and coagulation cascades_Homo sapiens_hsa046101.93810359
9MicroRNAs in cancer_Homo sapiens_hsa052061.92045497
10Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045501.90805587
11Proteoglycans in cancer_Homo sapiens_hsa052051.86590859
12Leukocyte transendothelial migration_Homo sapiens_hsa046701.80812373
13Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054121.79989986
14Transcriptional misregulation in cancer_Homo sapiens_hsa052021.72583821
15PI3K-Akt signaling pathway_Homo sapiens_hsa041511.72352878
16Small cell lung cancer_Homo sapiens_hsa052221.70302793
17Hedgehog signaling pathway_Homo sapiens_hsa043401.66818825
18Thyroid cancer_Homo sapiens_hsa052161.66180923
19Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054101.62388891
20Tight junction_Homo sapiens_hsa045301.61556834
21Pathways in cancer_Homo sapiens_hsa052001.60215273
22Arachidonic acid metabolism_Homo sapiens_hsa005901.57543165
23Prostate cancer_Homo sapiens_hsa052151.51925816
24Pathogenic Escherichia coli infection_Homo sapiens_hsa051301.47189791
25Malaria_Homo sapiens_hsa051441.38571287
26Dilated cardiomyopathy_Homo sapiens_hsa054141.37914044
27Notch signaling pathway_Homo sapiens_hsa043301.37796602
28Cell adhesion molecules (CAMs)_Homo sapiens_hsa045141.37485342
29Non-homologous end-joining_Homo sapiens_hsa034501.30938604
30Bacterial invasion of epithelial cells_Homo sapiens_hsa051001.30679687
31Cell cycle_Homo sapiens_hsa041101.29576850
32Regulation of actin cytoskeleton_Homo sapiens_hsa048101.28879618
33AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049331.28403259
34Selenocompound metabolism_Homo sapiens_hsa004501.26412002
35Biosynthesis of amino acids_Homo sapiens_hsa012301.23140770
36Rap1 signaling pathway_Homo sapiens_hsa040151.22452379
37N-Glycan biosynthesis_Homo sapiens_hsa005101.21613281
38Axon guidance_Homo sapiens_hsa043601.21436730
39Wnt signaling pathway_Homo sapiens_hsa043101.21262970
40One carbon pool by folate_Homo sapiens_hsa006701.21045040
41HTLV-I infection_Homo sapiens_hsa051661.16901363
42Viral myocarditis_Homo sapiens_hsa054161.14619993
43* Protein digestion and absorption_Homo sapiens_hsa049741.13530118
44Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030081.11443976
45Vitamin B6 metabolism_Homo sapiens_hsa007501.07518134
46NF-kappa B signaling pathway_Homo sapiens_hsa040641.06430073
47Toxoplasmosis_Homo sapiens_hsa051451.04161602
48Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004001.02417911
49Arginine biosynthesis_Homo sapiens_hsa002201.00500286
50Fatty acid biosynthesis_Homo sapiens_hsa000610.99933378
51Steroid biosynthesis_Homo sapiens_hsa001000.99820226
52Chronic myeloid leukemia_Homo sapiens_hsa052200.98415542
53Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.97848642
54Cytokine-cytokine receptor interaction_Homo sapiens_hsa040600.96188207
55TNF signaling pathway_Homo sapiens_hsa046680.95249811
56Citrate cycle (TCA cycle)_Homo sapiens_hsa000200.95073885
57Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.92776970
58Colorectal cancer_Homo sapiens_hsa052100.92609182
59Inflammatory bowel disease (IBD)_Homo sapiens_hsa053210.91863874
60RNA degradation_Homo sapiens_hsa030180.91074424
61Bladder cancer_Homo sapiens_hsa052190.90805871
62Ovarian steroidogenesis_Homo sapiens_hsa049130.90182738
63Melanoma_Homo sapiens_hsa052180.88991027
64Amoebiasis_Homo sapiens_hsa051460.87106257
65Pancreatic cancer_Homo sapiens_hsa052120.85680332
66Apoptosis_Homo sapiens_hsa042100.85515864
67Viral carcinogenesis_Homo sapiens_hsa052030.85269537
68Linoleic acid metabolism_Homo sapiens_hsa005910.84205270
69Glioma_Homo sapiens_hsa052140.83651033
70Ether lipid metabolism_Homo sapiens_hsa005650.82727826
712-Oxocarboxylic acid metabolism_Homo sapiens_hsa012100.82426579
72Thyroid hormone signaling pathway_Homo sapiens_hsa049190.81980751
73Glycosaminoglycan degradation_Homo sapiens_hsa005310.80333932
74mRNA surveillance pathway_Homo sapiens_hsa030150.79824945
75Hematopoietic cell lineage_Homo sapiens_hsa046400.79745716
76Non-small cell lung cancer_Homo sapiens_hsa052230.79186626
77Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.79022704
78Jak-STAT signaling pathway_Homo sapiens_hsa046300.77403130
79alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.76770843
80Ras signaling pathway_Homo sapiens_hsa040140.76567943
81RIG-I-like receptor signaling pathway_Homo sapiens_hsa046220.76491076
82Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010400.75635964
83Prion diseases_Homo sapiens_hsa050200.73141509
84Renal cell carcinoma_Homo sapiens_hsa052110.73006504
85Sphingolipid metabolism_Homo sapiens_hsa006000.72649891
86Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.72080758
87mTOR signaling pathway_Homo sapiens_hsa041500.71641998
88Endometrial cancer_Homo sapiens_hsa052130.71430056
89Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005320.70764668
90Cysteine and methionine metabolism_Homo sapiens_hsa002700.70472651
91Hepatitis B_Homo sapiens_hsa051610.69199933
92p53 signaling pathway_Homo sapiens_hsa041150.68682537
93Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.68313478
94Butirosin and neomycin biosynthesis_Homo sapiens_hsa005240.68206352
95Acute myeloid leukemia_Homo sapiens_hsa052210.68157924
96Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009700.66297045
97Circadian rhythm_Homo sapiens_hsa047100.65611718
98Hepatitis C_Homo sapiens_hsa051600.63745039
99Glucagon signaling pathway_Homo sapiens_hsa049220.62604011
100FoxO signaling pathway_Homo sapiens_hsa040680.61809764
101Insulin signaling pathway_Homo sapiens_hsa049100.61806145
102Thyroid hormone synthesis_Homo sapiens_hsa049180.61320566
103Nucleotide excision repair_Homo sapiens_hsa034200.61014122
104MAPK signaling pathway_Homo sapiens_hsa040100.60946148
105Melanogenesis_Homo sapiens_hsa049160.60783228
106Shigellosis_Homo sapiens_hsa051310.58459298
107Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.58291326
108Platelet activation_Homo sapiens_hsa046110.57851304
109AMPK signaling pathway_Homo sapiens_hsa041520.57362803
110Inositol phosphate metabolism_Homo sapiens_hsa005620.57208379
111Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.56946339
112Galactose metabolism_Homo sapiens_hsa000520.56883978
113NOD-like receptor signaling pathway_Homo sapiens_hsa046210.56342993
114HIF-1 signaling pathway_Homo sapiens_hsa040660.54543541
115Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.53061549
116Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005340.52781785
117Lysine degradation_Homo sapiens_hsa003100.52562764
118Other glycan degradation_Homo sapiens_hsa005110.51871858
119Carbon metabolism_Homo sapiens_hsa012000.51675553
120Pyruvate metabolism_Homo sapiens_hsa006200.50312173
121Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.49810425
122RNA transport_Homo sapiens_hsa030130.49778277
123Herpes simplex infection_Homo sapiens_hsa051680.49571088
124Sphingolipid signaling pathway_Homo sapiens_hsa040710.48262261
125Central carbon metabolism in cancer_Homo sapiens_hsa052300.48177240
126Influenza A_Homo sapiens_hsa051640.47998624
127Intestinal immune network for IgA production_Homo sapiens_hsa046720.47525735
128Longevity regulating pathway - mammal_Homo sapiens_hsa042110.47219194
129Pentose phosphate pathway_Homo sapiens_hsa000300.46790285
130Insulin resistance_Homo sapiens_hsa049310.46690582
131ErbB signaling pathway_Homo sapiens_hsa040120.46686270
132Vascular smooth muscle contraction_Homo sapiens_hsa042700.46470929
133Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.46306165
134Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.46074225
135Legionellosis_Homo sapiens_hsa051340.46056144
136Leishmaniasis_Homo sapiens_hsa051400.44642317
137T cell receptor signaling pathway_Homo sapiens_hsa046600.44405724
138Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.40874310
139Phosphatidylinositol signaling system_Homo sapiens_hsa040700.40294001

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