SLC35G2

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1synaptic vesicle exocytosis (GO:0016079)4.43369206
2positive regulation of calcium ion-dependent exocytosis (GO:0045956)4.37922450
3regulation of short-term neuronal synaptic plasticity (GO:0048172)4.32893583
4detection of calcium ion (GO:0005513)4.23780878
5COPI coating of Golgi vesicle (GO:0048205)4.20440713
6Golgi transport vesicle coating (GO:0048200)4.20440713
7regulation of synaptic vesicle exocytosis (GO:2000300)4.18848486
8neuronal action potential propagation (GO:0019227)4.16643076
9respiratory chain complex IV assembly (GO:0008535)3.86874626
10cellular ketone body metabolic process (GO:0046950)3.83752473
11platelet dense granule organization (GO:0060155)3.76632838
12neuron cell-cell adhesion (GO:0007158)3.75761098
13glutamate secretion (GO:0014047)3.71312513
14regulation of synaptic vesicle transport (GO:1902803)3.64952699
15insulin secretion (GO:0030073)3.60800057
16peptide hormone processing (GO:0016486)3.58654792
17synaptic vesicle maturation (GO:0016188)3.58537527
18retinal cone cell development (GO:0046549)3.56470639
19regulation of N-methyl-D-aspartate selective glutamate receptor activity (GO:2000310)3.55964719
20protein maturation by protein folding (GO:0022417)3.55439895
21negative regulation of catecholamine secretion (GO:0033604)3.53553736
22neuromuscular process controlling posture (GO:0050884)3.52367859
23regulation of hexokinase activity (GO:1903299)3.50687459
24regulation of glucokinase activity (GO:0033131)3.50687459
25neurotransmitter secretion (GO:0007269)3.50453427
26protein complex biogenesis (GO:0070271)3.42661961
27vocalization behavior (GO:0071625)3.42066044
28ketone body metabolic process (GO:1902224)3.41984842
29energy coupled proton transmembrane transport, against electrochemical gradient (GO:0015988)3.41518951
30ATP hydrolysis coupled proton transport (GO:0015991)3.41518951
31behavioral response to nicotine (GO:0035095)3.35505661
32cytochrome complex assembly (GO:0017004)3.35056021
33locomotory exploration behavior (GO:0035641)3.33562146
34activation of protein kinase A activity (GO:0034199)3.32404787
35ER overload response (GO:0006983)3.29489216
36regulation of vesicle fusion (GO:0031338)3.21699200
37water-soluble vitamin biosynthetic process (GO:0042364)3.21043495
38regulation of glucocorticoid secretion (GO:2000849)3.17077113
39preassembly of GPI anchor in ER membrane (GO:0016254)3.15942958
40endocrine pancreas development (GO:0031018)3.13568288
41mitochondrial respiratory chain complex assembly (GO:0033108)3.12407950
42C-terminal protein lipidation (GO:0006501)3.11359675
43regulation of insulin secretion (GO:0050796)3.09390852
44regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway (GO:19022353.08610105
45proline transport (GO:0015824)3.08317550
46dopamine biosynthetic process (GO:0042416)3.06285200
47positive regulation of insulin secretion (GO:0032024)3.05342543
48negative regulation of synaptic transmission, GABAergic (GO:0032229)3.04434681
49neurotransmitter transport (GO:0006836)3.03717450
50inositol phosphate catabolic process (GO:0071545)3.03495398
51transferrin transport (GO:0033572)3.03125725
52positive regulation of synaptic transmission, GABAergic (GO:0032230)3.01791226
53regulation of type B pancreatic cell apoptotic process (GO:2000674)3.01379875
54C-terminal protein amino acid modification (GO:0018410)3.00900380
55regulation of glutamate receptor signaling pathway (GO:1900449)2.99702557
56cell communication by electrical coupling involved in cardiac conduction (GO:0086064)2.99198085
57presynaptic membrane assembly (GO:0097105)2.96534360
58response to pheromone (GO:0019236)2.96158603
59protein localization to synapse (GO:0035418)2.96077430
60mating behavior (GO:0007617)2.95410009
61regulation of cilium movement (GO:0003352)2.94662651
62positive regulation of insulin secretion involved in cellular response to glucose stimulus (GO:003572.92181687
63negative regulation of norepinephrine secretion (GO:0010700)2.91456672
64retrograde vesicle-mediated transport, Golgi to ER (GO:0006890)2.89930263
65cellular response to glucagon stimulus (GO:0071377)2.89258684
66gamma-aminobutyric acid transport (GO:0015812)2.88807611
67cilium morphogenesis (GO:0060271)2.88668280
68membrane depolarization during cardiac muscle cell action potential (GO:0086012)2.87336012
69lactate metabolic process (GO:0006089)2.86498511
70mitochondrial respiratory chain complex I assembly (GO:0032981)2.85880632
71NADH dehydrogenase complex assembly (GO:0010257)2.85880632
72mitochondrial respiratory chain complex I biogenesis (GO:0097031)2.85880632
73trivalent inorganic cation transport (GO:0072512)2.85793931
74ferric iron transport (GO:0015682)2.85793931
75protein neddylation (GO:0045116)2.85020826
76regulation of peptide hormone secretion (GO:0090276)2.84727086
77gamma-aminobutyric acid signaling pathway (GO:0007214)2.84525133
78negative regulation of amine transport (GO:0051953)2.84329647
79regulation of peptide secretion (GO:0002791)2.82109934
80toxin metabolic process (GO:0009404)2.81164075
81neuron-neuron synaptic transmission (GO:0007270)2.80936389
82nonmotile primary cilium assembly (GO:0035058)2.80884704
83cerebellar Purkinje cell layer development (GO:0021680)2.80453816
84phosphorylated carbohydrate dephosphorylation (GO:0046838)2.79994520
85inositol phosphate dephosphorylation (GO:0046855)2.79994520
86regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor act2.77790602
87establishment of synaptic vesicle localization (GO:0097480)2.76966662
88synaptic vesicle transport (GO:0048489)2.76966662
89regulation of dopamine metabolic process (GO:0042053)2.76855885
90regulation of catecholamine metabolic process (GO:0042069)2.76855885
91regulation of penile erection (GO:0060405)2.76440731
92positive regulation of vesicle fusion (GO:0031340)2.75950627
93signal release (GO:0023061)2.75933675
94peptide hormone secretion (GO:0030072)2.75382738
95positive regulation of amino acid transport (GO:0051957)2.75148453
96regulation of neurotransmitter levels (GO:0001505)2.74465751
97positive regulation of exocytosis (GO:0045921)2.74013987
98positive regulation of synaptic transmission, dopaminergic (GO:0032226)2.72664506
99neurological system process involved in regulation of systemic arterial blood pressure (GO:0001976)2.72581103
100regulation of calcium ion-dependent exocytosis (GO:0017158)2.72572684
101epithelial cilium movement (GO:0003351)2.72305563
102exploration behavior (GO:0035640)2.72288042
103dendritic spine morphogenesis (GO:0060997)2.71894452
104fucose catabolic process (GO:0019317)2.71593265
105L-fucose metabolic process (GO:0042354)2.71593265
106L-fucose catabolic process (GO:0042355)2.71593265
107positive regulation of glycolytic process (GO:0045821)2.71088543
108positive regulation of potassium ion transmembrane transporter activity (GO:1901018)2.70937212
109negative regulation of neurotransmitter transport (GO:0051589)2.70882086
110startle response (GO:0001964)2.70629709
111response to nitrosative stress (GO:0051409)2.69782551
112innervation (GO:0060384)2.69735913
113anterograde synaptic vesicle transport (GO:0048490)2.68647366
114regulation of insulin secretion involved in cellular response to glucose stimulus (GO:0061178)2.68422682
115cell communication by electrical coupling (GO:0010644)2.67835603
116cellular potassium ion homeostasis (GO:0030007)2.67490883
117peptide secretion (GO:0002790)2.66916298
118auditory behavior (GO:0031223)2.66233477
119regulation of inhibitory postsynaptic membrane potential (GO:0060080)2.64533362
120positive regulation of action potential (GO:0045760)2.63861741
121cullin deneddylation (GO:0010388)2.63667218
122long-term memory (GO:0007616)2.62767901
123long-term synaptic potentiation (GO:0060291)2.61727249
124detection of light stimulus involved in sensory perception (GO:0050962)2.61429792
125detection of light stimulus involved in visual perception (GO:0050908)2.61429792
126photoreceptor cell maintenance (GO:0045494)2.59954527
127regulation of norepinephrine secretion (GO:0014061)2.59915863
128presynaptic membrane organization (GO:0097090)2.59307880
129negative regulation of dendrite development (GO:2000171)2.59277101
130negative regulation of neurotransmitter secretion (GO:0046929)2.59095987
131synapsis (GO:0007129)2.58390493
132glycosphingolipid biosynthetic process (GO:0006688)2.57951993
133postsynaptic membrane organization (GO:0001941)2.57629014
134regulation of hormone secretion (GO:0046883)2.57585252
135synaptic transmission, glutamatergic (GO:0035249)2.57419985
136positive regulation of peptide hormone secretion (GO:0090277)2.57229984
137regulation of exocytosis (GO:0017157)2.57155336
138transmission of nerve impulse (GO:0019226)2.57144128
139positive regulation of peptide secretion (GO:0002793)2.56984625
140signal peptide processing (GO:0006465)2.56902622
141peptidyl-cysteine modification (GO:0018198)2.55822212
142brain morphogenesis (GO:0048854)2.55677341
143regulation of corticosteroid hormone secretion (GO:2000846)2.55530282
144protein localization to cilium (GO:0061512)2.55370653
145mitochondrial electron transport, NADH to ubiquinone (GO:0006120)2.55232786
146nucleotide transmembrane transport (GO:1901679)2.54641166
147establishment of protein localization to mitochondrial membrane (GO:0090151)2.54387153
148regulation of synaptic transmission, GABAergic (GO:0032228)2.53627595
149nitric oxide mediated signal transduction (GO:0007263)2.53525544
150artery smooth muscle contraction (GO:0014824)2.52171989
151L-methionine biosynthetic process from methylthioadenosine (GO:0019509)2.49947098
152glycerophospholipid catabolic process (GO:0046475)2.45685225
153positive regulation of mitochondrial fission (GO:0090141)2.45629400
154cilium organization (GO:0044782)2.44409204
155protein deneddylation (GO:0000338)2.43943062
156C4-dicarboxylate transport (GO:0015740)2.43545593
157negative regulation of cytosolic calcium ion concentration (GO:0051481)2.42652734
158protein polyglutamylation (GO:0018095)2.42458939
159cilium assembly (GO:0042384)2.41632202
160mannosylation (GO:0097502)2.39555610
161negative regulation of membrane potential (GO:0045837)2.39328495
162protein-cofactor linkage (GO:0018065)2.38818386
163epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287)2.38398994
164protein K6-linked ubiquitination (GO:0085020)2.37611999
165DNA double-strand break processing (GO:0000729)2.37445605
166positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic proc2.37275225
167branched-chain amino acid catabolic process (GO:0009083)2.36938945
168RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394)2.35532022
169tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388)2.35532022
170intraciliary transport (GO:0042073)2.35437968
171axoneme assembly (GO:0035082)2.31733426
172positive regulation of meiosis (GO:0045836)2.29360528
173behavioral response to ethanol (GO:0048149)2.29158254
174nucleobase catabolic process (GO:0046113)2.28348936
175renal tubule morphogenesis (GO:0061333)2.27413333
176regulation of neurotransmitter uptake (GO:0051580)2.27074427
177protein prenylation (GO:0018342)2.24384098
178prenylation (GO:0097354)2.24384098
179G-protein coupled glutamate receptor signaling pathway (GO:0007216)2.24143994
180polyol catabolic process (GO:0046174)2.23183780
181negative regulation of neurological system process (GO:0031645)2.22906328
182tonic smooth muscle contraction (GO:0014820)2.21863733
183response to gravity (GO:0009629)2.20367938
184detection of mechanical stimulus involved in sensory perception of sound (GO:0050910)2.20156825
185GPI anchor metabolic process (GO:0006505)2.19714880
186anterograde axon cargo transport (GO:0008089)2.19064835
187mechanosensory behavior (GO:0007638)2.18991871
188vascular smooth muscle contraction (GO:0014829)2.17271329
189pyrimidine nucleobase catabolic process (GO:0006208)2.17247294

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1EZH2_22144423_ChIP-Seq_EOC_Human5.55036522
2GBX2_23144817_ChIP-Seq_PC3_Human3.45521028
3FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse3.31705412
4SUZ12_18692474_ChIP-Seq_MESCs_Mouse2.87516255
5REST_21632747_ChIP-Seq_MESCs_Mouse2.68693510
6SUZ12_18555785_ChIP-Seq_MESCs_Mouse2.68407162
7SUZ12_18692474_ChIP-Seq_MEFs_Mouse2.50289027
8JARID2_20064375_ChIP-Seq_MESCs_Mouse2.37096127
9SUZ12_20075857_ChIP-Seq_MESCs_Mouse2.35345366
10SUZ12_18974828_ChIP-Seq_MESCs_Mouse2.29459770
11JARID2_20075857_ChIP-Seq_MESCs_Mouse2.25931905
12CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons2.22992742
13MTF2_20144788_ChIP-Seq_MESCs_Mouse2.20323382
14REST_18959480_ChIP-ChIP_MESCs_Mouse2.19934481
15SUZ12_16625203_ChIP-ChIP_MESCs_Mouse2.17184951
16HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human2.16823602
17GLI1_17442700_ChIP-ChIP_MESCs_Mouse2.15544186
18KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human2.12730910
19TAF15_26573619_Chip-Seq_HEK293_Human2.12040854
20CEBPD_23245923_ChIP-Seq_MEFs_Mouse2.11951891
21CTBP2_25329375_ChIP-Seq_LNCAP_Human2.11428329
22EWS_26573619_Chip-Seq_HEK293_Human2.10858770
23EZH2_27304074_Chip-Seq_ESCs_Mouse2.10076639
24TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse2.06083122
25RNF2_18974828_ChIP-Seq_MESCs_Mouse2.03712778
26EZH2_18974828_ChIP-Seq_MESCs_Mouse2.03712778
27EED_16625203_ChIP-ChIP_MESCs_Mouse2.03132339
28NOTCH1_17114293_ChIP-ChIP_T-ALL_Human2.00839860
29NR4A2_19515692_ChIP-ChIP_MN9D_Mouse2.00428123
30GABP_17652178_ChIP-ChIP_JURKAT_Human1.96625328
31EZH2_27294783_Chip-Seq_ESCs_Mouse1.95403555
32FLI1_27457419_Chip-Seq_LIVER_Mouse1.94864293
33SALL1_21062744_ChIP-ChIP_HESCs_Human1.94467946
34E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse1.91817084
35IKZF1_21737484_ChIP-ChIP_HCT116_Human1.91475951
36BMI1_23680149_ChIP-Seq_NPCS_Mouse1.89019904
37SUZ12_27294783_Chip-Seq_ESCs_Mouse1.88391269
38ZFP57_27257070_Chip-Seq_ESCs_Mouse1.86199714
39IGF1R_20145208_ChIP-Seq_DFB_Human1.85449271
40CTBP1_25329375_ChIP-Seq_LNCAP_Human1.79018060
41SMAD4_21799915_ChIP-Seq_A2780_Human1.78114416
42RARB_27405468_Chip-Seq_BRAIN_Mouse1.74899599
43NR3C1_23031785_ChIP-Seq_PC12_Mouse1.72730668
44VDR_22108803_ChIP-Seq_LS180_Human1.70866464
45POU3F2_20337985_ChIP-ChIP_501MEL_Human1.70510576
46EST1_17652178_ChIP-ChIP_JURKAT_Human1.69298713
47ZNF274_21170338_ChIP-Seq_K562_Hela1.65461183
48PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.64264167
49DROSHA_22980978_ChIP-Seq_HELA_Human1.64249280
50RNF2_27304074_Chip-Seq_ESCs_Mouse1.62996068
51P300_19829295_ChIP-Seq_ESCs_Human1.62497254
52PIAS1_25552417_ChIP-Seq_VCAP_Human1.60903420
53ELK1_19687146_ChIP-ChIP_HELA_Human1.55522341
54MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.55374093
55PCGF2_27294783_Chip-Seq_ESCs_Mouse1.50039519
56GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.47350491
57TP53_22573176_ChIP-Seq_HFKS_Human1.46843728
58TOP2B_26459242_ChIP-Seq_MCF-7_Human1.44429297
59BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse1.39505703
60CBP_20019798_ChIP-Seq_JUKART_Human1.39225435
61IRF4_20064451_ChIP-Seq_CD4+T_Mouse1.39225435
62OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.38642006
63EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human1.36722563
64STAT3_23295773_ChIP-Seq_U87_Human1.34292895
65EZH2_27294783_Chip-Seq_NPCs_Mouse1.33174785
66MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human1.31715671
67MYC_18940864_ChIP-ChIP_HL60_Human1.31410817
68SOX2_21211035_ChIP-Seq_LN229_Gbm1.30497468
69HTT_18923047_ChIP-ChIP_STHdh_Human1.29259307
70AR_25329375_ChIP-Seq_VCAP_Human1.28306932
71PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse1.28239187
72SRF_21415370_ChIP-Seq_HL-1_Mouse1.26904041
73SUZ12_27294783_Chip-Seq_NPCs_Mouse1.25987103
74AR_21572438_ChIP-Seq_LNCaP_Human1.25902240
75SMAD3_21741376_ChIP-Seq_EPCs_Human1.25410457
76SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.25348856
77NANOG_19829295_ChIP-Seq_ESCs_Human1.25001564
78SOX2_19829295_ChIP-Seq_ESCs_Human1.25001564
79SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.24869918
80PDX1_19855005_ChIP-ChIP_MIN6_Mouse1.23015340
81KLF5_20875108_ChIP-Seq_MESCs_Mouse1.21024128
82BCAT_22108803_ChIP-Seq_LS180_Human1.20021489
83CDX2_19796622_ChIP-Seq_MESCs_Mouse1.19807316
84CBX2_27304074_Chip-Seq_ESCs_Mouse1.19705974
85SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.19107774
86NOTCH1_21737748_ChIP-Seq_TLL_Human1.18921053
87PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse1.18737122
88FUS_26573619_Chip-Seq_HEK293_Human1.18007113
89AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human1.16310983
90NFE2_27457419_Chip-Seq_LIVER_Mouse1.15963594
91HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse1.15625436
92TCF4_23295773_ChIP-Seq_U87_Human1.15373541
93MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse1.15268710
94RNF2_27304074_Chip-Seq_NSC_Mouse1.14436929
95NR3C1_21868756_ChIP-Seq_MCF10A_Human1.14041696
96TEAD4_22529382_ChIP-Seq_TROPHECTODERM_Mouse1.14014468
97TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human1.13984161
98ESRRB_18555785_ChIP-Seq_MESCs_Mouse1.13123548
99RUNX2_22187159_ChIP-Seq_PCA_Human1.12556286
100PHC1_16625203_ChIP-ChIP_MESCs_Mouse1.12088116
101REST_19997604_ChIP-ChIP_NEURONS_Mouse1.10833537
102PADI4_21655091_ChIP-ChIP_MCF-7_Human1.10455958
103CDX2_22108803_ChIP-Seq_LS180_Human1.09640382
104GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse1.09264812
105TAL1_26923725_Chip-Seq_HPCs_Mouse1.07933030
106STAT3_18555785_Chip-Seq_ESCs_Mouse1.06756827
107FOXA1_27270436_Chip-Seq_PROSTATE_Human1.05476627
108FOXA1_25329375_ChIP-Seq_VCAP_Human1.05476627
109CRX_20693478_ChIP-Seq_RETINA_Mouse1.04539192
110AR_19668381_ChIP-Seq_PC3_Human1.04426794
111ZNF217_24962896_ChIP-Seq_MCF-7_Human1.04352263
112SMAD4_21741376_ChIP-Seq_EPCs_Human1.03123225
113VDR_23849224_ChIP-Seq_CD4+_Human1.03119730
114CRX_20693478_ChIP-Seq_ADULT_RETINA_Mouse1.02890440
115RCOR3_21632747_ChIP-Seq_MESCs_Mouse1.02807526
116IRF1_19129219_ChIP-ChIP_H3396_Human1.02056899
117FOXA1_21572438_ChIP-Seq_LNCaP_Human1.01685281
118SMAD3_21741376_ChIP-Seq_ESCs_Human1.01575495
119NANOG_18555785_Chip-Seq_ESCs_Mouse1.01537798
120CMYC_18555785_Chip-Seq_ESCs_Mouse1.01292115
121RNF2_16625203_ChIP-ChIP_MESCs_Mouse1.00056386
122YAP1_20516196_ChIP-Seq_MESCs_Mouse0.99985024
123CDX2_21402776_ChIP-Seq_INTESTINAL-VILLUS_Mouse0.99957421
124E2F1_18555785_Chip-Seq_ESCs_Mouse0.99160307
125FOXP2_21765815_ChIP-ChIP_NEURO2A_Mouse0.97940766
126ERG_21242973_ChIP-ChIP_JURKAT_Human0.97865269
127FLI1_21867929_ChIP-Seq_TH2_Mouse0.97834938
128UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human0.97630126
129ER_23166858_ChIP-Seq_MCF-7_Human0.97478724
130OLIG2_26023283_ChIP-Seq_AINV15_Mouse0.97118682
131TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.95287966
132JUN_21703547_ChIP-Seq_K562_Human0.92567358
133ZFP322A_24550733_ChIP-Seq_MESCs_Mouse0.92511167
134LMO2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.90637586
135TCF4_22108803_ChIP-Seq_LS180_Human0.90171428
136P53_22127205_ChIP-Seq_FIBROBLAST_Human0.89363336
137BACH1_22875853_ChIP-PCR_HELA_AND_SCP4_Human0.87712996
138RING1B_27294783_Chip-Seq_ESCs_Mouse0.87693286
139TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse0.87296060
140KDM2B_26808549_Chip-Seq_REH_Human0.86749959
141RCOR1_19997604_ChIP-ChIP_NEURONS_Mouse0.86566032
142MEIS1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse0.84633980
143PRDM14_20953172_ChIP-Seq_ESCs_Human0.84508647
144EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse0.82425566
145P53_22387025_ChIP-Seq_ESCs_Mouse0.81960905
146DMRT1_21621532_ChIP-ChIP_FETAL_Ovary0.81403570

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0009780_abnormal_chondrocyte_physiolo3.12832803
2MP0003880_abnormal_central_pattern3.08374599
3MP0004859_abnormal_synaptic_plasticity2.99846170
4MP0000013_abnormal_adipose_tissue2.98141374
5MP0003122_maternal_imprinting2.95901624
6MP0004270_analgesia2.90483282
7MP0002909_abnormal_adrenal_gland2.90136666
8MP0002837_dystrophic_cardiac_calcinosis2.87953940
9MP0003635_abnormal_synaptic_transmissio2.82822401
10MP0010386_abnormal_urinary_bladder2.79154507
11MP0008877_abnormal_DNA_methylation2.62051610
12MP0006276_abnormal_autonomic_nervous2.60165949
13MP0009745_abnormal_behavioral_response2.49308039
14MP0009046_muscle_twitch2.48452396
15MP0004043_abnormal_pH_regulation2.42569883
16MP0002064_seizures2.41983062
17MP0005645_abnormal_hypothalamus_physiol2.38290602
18MP0005646_abnormal_pituitary_gland2.27357867
19MP0003283_abnormal_digestive_organ2.26930896
20MP0002572_abnormal_emotion/affect_behav2.24755172
21MP0003183_abnormal_peptide_metabolism2.24606795
22MP0002063_abnormal_learning/memory/cond2.21749489
23MP0002734_abnormal_mechanical_nocicepti2.19586194
24MP0005379_endocrine/exocrine_gland_phen2.18628269
25MP0002272_abnormal_nervous_system2.11987232
26MP0003011_delayed_dark_adaptation2.09865089
27MP0002102_abnormal_ear_morphology2.07276277
28MP0005423_abnormal_somatic_nervous2.01617369
29MP0001968_abnormal_touch/_nociception2.01462484
30MP0002638_abnormal_pupillary_reflex2.00369852
31MP0001501_abnormal_sleep_pattern1.99574464
32MP0002733_abnormal_thermal_nociception1.98006310
33MP0002735_abnormal_chemical_nociception1.93180084
34MP0001986_abnormal_taste_sensitivity1.92256655
35MP0002693_abnormal_pancreas_physiology1.90291343
36MP0006072_abnormal_retinal_apoptosis1.88369580
37MP0005084_abnormal_gallbladder_morpholo1.87926377
38MP0002822_catalepsy1.80503260
39MP0001440_abnormal_grooming_behavior1.78975603
40MP0001970_abnormal_pain_threshold1.78675180
41MP0001944_abnormal_pancreas_morphology1.76529480
42MP0006054_spinal_hemorrhage1.71391726
43MP0001529_abnormal_vocalization1.71246307
44MP0001502_abnormal_circadian_rhythm1.70975470
45MP0001486_abnormal_startle_reflex1.68533266
46MP0002067_abnormal_sensory_capabilities1.68383048
47MP0001984_abnormal_olfaction1.66713023
48MP0002557_abnormal_social/conspecific_i1.60124570
49MP0002184_abnormal_innervation1.58214298
50MP0005386_behavior/neurological_phenoty1.49520056
51MP0004924_abnormal_behavior1.49520056
52MP0003195_calcinosis1.48130580
53MP0002938_white_spotting1.47795471
54MP0001905_abnormal_dopamine_level1.46905160
55MP0002736_abnormal_nociception_after1.46854841
56MP0003787_abnormal_imprinting1.46149227
57MP0004133_heterotaxia1.44093355
58MP0005187_abnormal_penis_morphology1.43243269
59MP0002876_abnormal_thyroid_physiology1.42020772
60MP0005367_renal/urinary_system_phenotyp1.39076974
61MP0000516_abnormal_urinary_system1.39076974
62MP0004142_abnormal_muscle_tone1.36841833
63MP0002928_abnormal_bile_duct1.34960275
64MP0004858_abnormal_nervous_system1.33587777
65MP0004215_abnormal_myocardial_fiber1.29820501
66MP0002078_abnormal_glucose_homeostasis1.27474903
67MP0005535_abnormal_body_temperature1.25026431
68MP0000427_abnormal_hair_cycle1.23717319
69MP0000631_abnormal_neuroendocrine_gland1.22080728
70MP0003329_amyloid_beta_deposits1.21685023
71MP0000569_abnormal_digit_pigmentation1.18875098
72MP0008569_lethality_at_weaning1.18375300
73MP0003121_genomic_imprinting1.17807332
74MP0006292_abnormal_olfactory_placode1.15139898
75MP0000955_abnormal_spinal_cord1.14923584
76MP0002160_abnormal_reproductive_system1.13292281
77MP0002163_abnormal_gland_morphology1.13104520
78MP0008058_abnormal_DNA_repair1.12535502
79MP0002877_abnormal_melanocyte_morpholog1.12057708
80MP0000003_abnormal_adipose_tissue1.10945799
81MP0002066_abnormal_motor_capabilities/c1.09757452
82MP0005551_abnormal_eye_electrophysiolog1.07186214
83MP0001756_abnormal_urination1.04957824
84MP0002882_abnormal_neuron_morphology1.04576114
85MP0003879_abnormal_hair_cell1.04342400
86MP0008775_abnormal_heart_ventricle1.04169845
87MP0000647_abnormal_sebaceous_gland1.02042533
88MP0001188_hyperpigmentation1.01538561
89MP0004811_abnormal_neuron_physiology1.01326600
90MP0008961_abnormal_basal_metabolism0.97527245
91MP0003123_paternal_imprinting0.97297885
92MP0003718_maternal_effect0.97217326
93MP0001664_abnormal_digestion0.96702251
94MP0009697_abnormal_copulation0.95589098
95MP0000372_irregular_coat_pigmentation0.94480057
96MP0001765_abnormal_ion_homeostasis0.93302596
97MP0003633_abnormal_nervous_system0.93144270
98MP0002069_abnormal_eating/drinking_beha0.93135384
99MP0000778_abnormal_nervous_system0.92891705
100MP0005253_abnormal_eye_physiology0.92571964
101MP0002229_neurodegeneration0.92172758
102MP0005332_abnormal_amino_acid0.92128387
103MP0005167_abnormal_blood-brain_barrier0.91360838
104MP0003953_abnormal_hormone_level0.91245435
105MP0004885_abnormal_endolymph0.89791763
106MP0008872_abnormal_physiological_respon0.88814700
107MP0008789_abnormal_olfactory_epithelium0.86774782
108MP0001879_abnormal_lymphatic_vessel0.86197697
109MP0005448_abnormal_energy_balance0.83583266
110MP0008875_abnormal_xenobiotic_pharmacok0.83250390
111MP0003186_abnormal_redox_activity0.83075808
112MP0005195_abnormal_posterior_eye0.82716771
113MP0006036_abnormal_mitochondrial_physio0.82548733
114MP0002751_abnormal_autonomic_nervous0.82451108
115MP0010368_abnormal_lymphatic_system0.82328578
116MP0005499_abnormal_olfactory_system0.81145636
117MP0005394_taste/olfaction_phenotype0.81145636
118MP0003172_abnormal_lysosome_physiology0.80884432
119MP0000639_abnormal_adrenal_gland0.80637233
120MP0004085_abnormal_heartbeat0.80581430
121MP0005389_reproductive_system_phenotype0.80366013
122MP0003634_abnormal_glial_cell0.80030525
123MP0004145_abnormal_muscle_electrophysio0.78924916
124MP0002177_abnormal_outer_ear0.78309650
125MP0010329_abnormal_lipoprotein_level0.78177359
126MP0002234_abnormal_pharynx_morphology0.77956301
127MP0000462_abnormal_digestive_system0.76629947
128MP0002090_abnormal_vision0.76568607
129MP0004484_altered_response_of0.76365279
130MP0005220_abnormal_exocrine_pancreas0.74089600
131MP0000538_abnormal_urinary_bladder0.73156187
132MP0000230_abnormal_systemic_arterial0.73105281
133MP0003959_abnormal_lean_body0.71257422
134MP0000678_abnormal_parathyroid_gland0.70200709
135MP0001963_abnormal_hearing_physiology0.69663288
136MP0003631_nervous_system_phenotype0.69366580
137MP0002152_abnormal_brain_morphology0.67407999
138MP0004742_abnormal_vestibular_system0.67241229

Predicted human phenotypes

RankGene SetZ-score
1Elevated circulating parathyroid hormone (PTH) level (HP:0003165)5.05434313
2Focal motor seizures (HP:0011153)4.82147438
3Atonic seizures (HP:0010819)4.52387120
4Hyperinsulinemic hypoglycemia (HP:0000825)4.43966482
5Pheochromocytoma (HP:0002666)4.43681068
6Hypoglycemic seizures (HP:0002173)4.39472418
7Neuroendocrine neoplasm (HP:0100634)4.12856247
8Visual hallucinations (HP:0002367)3.87134499
9Abnormality of calcium-phosphate metabolism (HP:0100530)3.84817666
10Symptomatic seizures (HP:0011145)3.73685385
11Abnormality of midbrain morphology (HP:0002418)3.67709914
12Molar tooth sign on MRI (HP:0002419)3.67709914
13Pancreatic fibrosis (HP:0100732)3.62201108
14True hermaphroditism (HP:0010459)3.57050924
15Hypothermia (HP:0002045)3.50330032
16Epileptic encephalopathy (HP:0200134)3.46230951
17Pancreatic cysts (HP:0001737)3.37669033
18Focal seizures (HP:0007359)3.34522937
19Absence seizures (HP:0002121)3.32852508
20Agitation (HP:0000713)3.29351270
21Limb dystonia (HP:0002451)3.27197073
22Failure to thrive in infancy (HP:0001531)3.19233486
233-Methylglutaconic aciduria (HP:0003535)3.04334814
24Dialeptic seizures (HP:0011146)3.01707779
25Generalized tonic-clonic seizures (HP:0002069)2.98509343
26Intestinal atresia (HP:0011100)2.96952888
27Febrile seizures (HP:0002373)2.92090435
28EEG with generalized epileptiform discharges (HP:0011198)2.89772255
29Epileptiform EEG discharges (HP:0011182)2.88092892
30Progressive cerebellar ataxia (HP:0002073)2.82217409
31Ketoacidosis (HP:0001993)2.81166801
32Abnormal hair whorl (HP:0010721)2.77736390
33Nephronophthisis (HP:0000090)2.76891533
34Anxiety (HP:0000739)2.76687556
35Myokymia (HP:0002411)2.76151905
36Hypsarrhythmia (HP:0002521)2.74600153
37Hypoglycemic coma (HP:0001325)2.71032692
38Gait imbalance (HP:0002141)2.65533235
39Increased CSF lactate (HP:0002490)2.63961110
40Menstrual irregularities (HP:0000858)2.61671838
41Medial flaring of the eyebrow (HP:0010747)2.59842084
42Aplasia/Hypoplasia of the tongue (HP:0010295)2.55028038
43Congenital primary aphakia (HP:0007707)2.54443432
44Hepatic necrosis (HP:0002605)2.51422562
45Oligomenorrhea (HP:0000876)2.48387112
46Hypercortisolism (HP:0001578)2.47917754
47Hepatocellular necrosis (HP:0001404)2.43843684
48Abnormal mitochondria in muscle tissue (HP:0008316)2.43543407
49Decreased circulating renin level (HP:0003351)2.41285466
50Depression (HP:0000716)2.40385638
51Acute necrotizing encephalopathy (HP:0006965)2.38421401
52Truncal ataxia (HP:0002078)2.38363284
53Hyperglycemia (HP:0003074)2.37134919
54Bile duct proliferation (HP:0001408)2.36341056
55Abnormal biliary tract physiology (HP:0012439)2.36341056
56Abnormality of the renal cortex (HP:0011035)2.34857442
57Congenital stationary night blindness (HP:0007642)2.32510560
58Insulin-resistant diabetes mellitus (HP:0000831)2.31702221
59Abnormality of the renal medulla (HP:0100957)2.31690080
60Occipital encephalocele (HP:0002085)2.31604686
61Hemiparesis (HP:0001269)2.31217171
62Neoplasm of the adrenal cortex (HP:0100641)2.29698596
63Large for gestational age (HP:0001520)2.28917465
64Nephrogenic diabetes insipidus (HP:0009806)2.28453656
65Polyphagia (HP:0002591)2.28367620
66Renal cortical cysts (HP:0000803)2.27071005
67Furrowed tongue (HP:0000221)2.26957284
68Genital tract atresia (HP:0001827)2.26232520
69Supranuclear gaze palsy (HP:0000605)2.25293372
70Vaginal atresia (HP:0000148)2.24852882
71Cystic liver disease (HP:0006706)2.24239195
72Methylmalonic acidemia (HP:0002912)2.20894532
73Hyperventilation (HP:0002883)2.20830314
74Psychosis (HP:0000709)2.20744290
75Poor suck (HP:0002033)2.18648794
76Attenuation of retinal blood vessels (HP:0007843)2.17271282
77Abnormality of the pancreatic islet cells (HP:0006476)2.16613996
78Abnormality of endocrine pancreas physiology (HP:0012093)2.16613996
79Sclerocornea (HP:0000647)2.14197327
80Abnormal eating behavior (HP:0100738)2.13739314
81Progressive macrocephaly (HP:0004481)2.11908764
82Postural tremor (HP:0002174)2.11788085
83Ketosis (HP:0001946)2.10694966
84Hypoventilation (HP:0002791)2.09813962
85Gaze-evoked nystagmus (HP:0000640)2.07870075
86Late onset (HP:0003584)2.07627978
87Aplasia/Hypoplasia of the tibia (HP:0005772)2.07267020
88Abnormality of the anterior horn cell (HP:0006802)2.04977170
89Degeneration of anterior horn cells (HP:0002398)2.04977170
90Abnormal rod and cone electroretinograms (HP:0008323)2.04651164
91Tubular atrophy (HP:0000092)2.03436786
92Abolished electroretinogram (ERG) (HP:0000550)2.02302233
93Polydipsia (HP:0001959)2.01803907
94Abnormal drinking behavior (HP:0030082)2.01803907
95Increased hepatocellular lipid droplets (HP:0006565)2.00835319
96Neoplasm of the peripheral nervous system (HP:0100007)2.00617761
97Papilledema (HP:0001085)2.00596103
98Short tibia (HP:0005736)2.00032485
99Dysostosis multiplex (HP:0000943)2.00013028
100Restlessness (HP:0000711)1.99977754
101Metaphyseal dysplasia (HP:0100255)1.99729455
102Lipid accumulation in hepatocytes (HP:0006561)1.99181422
103Neurofibrillary tangles (HP:0002185)1.98831313
104Cerebral edema (HP:0002181)1.98764769
105Retinal atrophy (HP:0001105)1.96815084
106Methylmalonic aciduria (HP:0012120)1.96552580
107Pancreatic islet-cell hyperplasia (HP:0004510)1.95953059
108Osteomalacia (HP:0002749)1.95811867
109Aplasia/hypoplasia of the uterus (HP:0008684)1.93802952
110Labial hypoplasia (HP:0000066)1.93414491
111Blue irides (HP:0000635)1.93167944
112Diplopia (HP:0000651)1.92926274
113Abnormality of binocular vision (HP:0011514)1.92926274
114Acute encephalopathy (HP:0006846)1.92691846
115Chronic hepatic failure (HP:0100626)1.92401949
116Renal Fanconi syndrome (HP:0001994)1.91783324
117Muscular hypotonia of the trunk (HP:0008936)1.91083195
118Type II lissencephaly (HP:0007260)1.90976051
119Cortical visual impairment (HP:0100704)1.90923449
120Male pseudohermaphroditism (HP:0000037)1.90014026
121Lissencephaly (HP:0001339)1.88381167
122Severe muscular hypotonia (HP:0006829)1.88104679
123Absent speech (HP:0001344)1.87912047
124Dysautonomia (HP:0002459)1.86606261
125Hyperthyroidism (HP:0000836)1.85878661
126Increased serum lactate (HP:0002151)1.85867087
127Retinal dysplasia (HP:0007973)1.85681549
128Hyperparathyroidism (HP:0000843)1.85131168
129Aplasia/Hypoplasia of the lens (HP:0008063)1.84031404
130Mitochondrial inheritance (HP:0001427)1.83547358
131Postaxial hand polydactyly (HP:0001162)1.83543347
132Broad-based gait (HP:0002136)1.82975205
133Bradykinesia (HP:0002067)1.82680566
134Constricted visual fields (HP:0001133)1.81969325
135Dysdiadochokinesis (HP:0002075)1.80983707
136Mucopolysacchariduria (HP:0008155)1.80954859
137Urinary glycosaminoglycan excretion (HP:0003541)1.80954859
138Scanning speech (HP:0002168)1.80436278
139Testicular neoplasm (HP:0010788)1.80368405
140Postaxial foot polydactyly (HP:0001830)1.78975444
141Action tremor (HP:0002345)1.78711308
142Abnormality of macular pigmentation (HP:0008002)1.78648599
143Abnormality of alanine metabolism (HP:0010916)1.78543843
144Hyperalaninemia (HP:0003348)1.78543843
145Abnormality of pyruvate family amino acid metabolism (HP:0010915)1.78543843
146Progressive inability to walk (HP:0002505)1.76623003
147Adrenal overactivity (HP:0002717)1.76494549
148Neoplasm of the adrenal gland (HP:0100631)1.75776663
149Abnormality of the metopic suture (HP:0005556)1.75538902
150Resting tremor (HP:0002322)1.75079281
151Hypokalemia (HP:0002900)1.75061740
152Optic disc pallor (HP:0000543)1.74490954
153Growth hormone excess (HP:0000845)1.73931146
154Hypomagnesemia (HP:0002917)1.73265907
155Cerebral inclusion bodies (HP:0100314)1.71954525
156Amblyopia (HP:0000646)1.70979660
157Parkinsonism with favorable response to dopaminergic medication (HP:0002548)1.70659130
158Respiratory failure (HP:0002878)1.70658703
159Prominent metopic ridge (HP:0005487)1.70176155
160Abnormal pupillary function (HP:0007686)1.69771035
161Specific learning disability (HP:0001328)1.69483599
162Intracellular accumulation of autofluorescent lipopigment storage material (HP:0003204)1.69433171
163Narrow forehead (HP:0000341)1.68928859
164Abnormal pancreas size (HP:0012094)1.68254015

Predicted kinase interactions (KEA)

RankGene SetZ-score
1NTRK33.85691520
2INSRR3.69145850
3MAP4K23.30079566
4MAP3K123.14433686
5MAPK152.80769514
6MAP3K42.70775368
7MAP2K72.69233865
8CASK2.53404647
9WNK42.48281446
10ARAF2.39534256
11MAP3K92.33676203
12WNK32.19719502
13NTRK12.19268759
14PASK2.11083844
15TRIM282.03405896
16TIE12.00929860
17PRKD32.00376188
18MAP3K21.91928204
19MINK11.87786782
20CAMKK21.85153143
21GRK11.82347917
22MAP2K41.77842594
23AKT31.71787215
24ZAK1.71600336
25HIPK21.69909179
26PINK11.68060354
27NUAK11.67732921
28UHMK11.63090664
29NTRK21.61465993
30CSNK1G11.60374431
31MARK11.59718650
32FGFR21.57529576
33MST41.56845849
34GRK51.54695480
35EIF2AK31.49591241
36BRAF1.45777097
37FRK1.39242365
38LIMK11.34645840
39STK38L1.34370956
40PLK31.32928153
41CSNK1A1L1.31759756
42EPHA41.30509772
43BMPR21.15843523
44CDK51.13652441
45PAK31.12936412
46PNCK1.11383542
47WNK11.11324783
48PRKCE1.10783506
49KSR21.09508754
50VRK11.08199196
51PRKCG1.07986827
52MAP3K11.06664588
53STK161.06185946
54MAPK131.03468205
55PLK21.03340382
56CAMKK11.00505663
57TNK20.99150254
58SRPK10.98041148
59SGK2230.97158264
60SGK4940.97158264
61CAMK2D0.94147349
62PTK2B0.93619757
63CAMK2A0.93436852
64SCYL20.93268498
65ADRBK20.93227905
66TAOK30.93147017
67EIF2AK10.92095200
68STK390.91815721
69CDC42BPA0.91277786
70RIPK40.90639982
71CAMK2B0.90094622
72FER0.89568422
73PRKCH0.89360878
74TNIK0.87996080
75PAK60.86158057
76MKNK20.84991182
77TLK10.83155855
78DYRK1A0.82713723
79SGK20.81039634
80DYRK20.77959188
81MYLK0.77188162
82VRK20.76522604
83NME10.75837528
84PRPF4B0.75535893
85BMPR1B0.75012972
86MAP3K130.73923352
87STK30.73252612
88CSNK1G20.72770564
89DAPK20.72268940
90PIK3CG0.71484082
91BCKDK0.70893907
92RET0.70112833
93PHKG10.70050027
94PHKG20.70050027
95DAPK10.70038867
96CAMK2G0.69878872
97CDK190.67910793
98OXSR10.64733452
99BCR0.62987040
100FES0.62849774
101PRKD20.62746503
102ERBB40.61401687
103ADRBK10.61058232
104STK240.59363921
105KSR10.59164049
106GRK70.53358734
107ACVR1B0.53152932
108CDK140.52539617
109PLK10.52138298
110MAP2K10.51842146
111RPS6KA20.51003630
112NEK10.51000287
113PRKACA0.50795733
114CSNK1G30.49047201
115CAMK10.48567306
116SGK10.48416744
117PRKCI0.45689654
118MUSK0.45318253
119SGK30.45059977
120PRKG10.44493854
121ERBB30.43679938
122RPS6KA50.43437955
123MAP2K60.43367021
124TESK10.43125611
125PDPK10.42438889
126SIK30.41434452
127MKNK10.40871672
128NEK60.40669701
129PTK20.40482228
130CSNK1D0.40027818
131PLK40.39114254
132CDK180.39110051
133LMTK20.38681828
134STK380.37509555
135CSNK1A10.37481102
136BRSK20.37304581
137CDK150.35910547
138BUB10.35656652
139ROCK10.35204645
140PRKAA10.34667679
141CCNB10.34488604
142MAPKAPK50.34134096
143TSSK60.33479780
144PDK30.33210471
145PDK40.33210471
146CDK30.33065070
147ATM0.30440243
148PRKCA0.29451328
149EPHB20.27239780
150CAMK1G0.26824290
151CSNK1E0.26751797
152GSK3A0.26407874

Predicted pathways (KEGG)

RankGene SetZ-score
1Maturity onset diabetes of the young_Homo sapiens_hsa049504.15285202
2Synaptic vesicle cycle_Homo sapiens_hsa047213.18461984
3Insulin secretion_Homo sapiens_hsa049112.93108507
4Nicotine addiction_Homo sapiens_hsa050332.67239741
5Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005632.63587294
6Protein export_Homo sapiens_hsa030602.61818002
7Vibrio cholerae infection_Homo sapiens_hsa051102.56826998
8Collecting duct acid secretion_Homo sapiens_hsa049662.55499132
9GABAergic synapse_Homo sapiens_hsa047272.36615090
10Amphetamine addiction_Homo sapiens_hsa050312.16753603
11Retrograde endocannabinoid signaling_Homo sapiens_hsa047232.14003904
12Cocaine addiction_Homo sapiens_hsa050302.12494513
13Oxidative phosphorylation_Homo sapiens_hsa001902.09576695
14Taste transduction_Homo sapiens_hsa047422.09439639
15Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049611.98674016
16Circadian entrainment_Homo sapiens_hsa047131.98387596
17Morphine addiction_Homo sapiens_hsa050321.95722458
18Dopaminergic synapse_Homo sapiens_hsa047281.90409004
19Terpenoid backbone biosynthesis_Homo sapiens_hsa009001.88480310
20Propanoate metabolism_Homo sapiens_hsa006401.88079118
21Long-term potentiation_Homo sapiens_hsa047201.85159925
22Vasopressin-regulated water reabsorption_Homo sapiens_hsa049621.82400450
23Sulfur metabolism_Homo sapiens_hsa009201.81904307
24Valine, leucine and isoleucine degradation_Homo sapiens_hsa002801.79723117
25Serotonergic synapse_Homo sapiens_hsa047261.78467408
26Glutamatergic synapse_Homo sapiens_hsa047241.64468354
27Vitamin B6 metabolism_Homo sapiens_hsa007501.60644557
28RNA polymerase_Homo sapiens_hsa030201.59330606
29Parkinsons disease_Homo sapiens_hsa050121.51425885
30Cholinergic synapse_Homo sapiens_hsa047251.46639312
31Olfactory transduction_Homo sapiens_hsa047401.45942405
32Long-term depression_Homo sapiens_hsa047301.45049156
33Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001301.43693175
34Nitrogen metabolism_Homo sapiens_hsa009101.41081755
35Type I diabetes mellitus_Homo sapiens_hsa049401.39718464
36Basal transcription factors_Homo sapiens_hsa030221.39396618
37Type II diabetes mellitus_Homo sapiens_hsa049301.38933375
38Alzheimers disease_Homo sapiens_hsa050101.36640000
39Salivary secretion_Homo sapiens_hsa049701.35663014
40Citrate cycle (TCA cycle)_Homo sapiens_hsa000201.35225806
41Steroid biosynthesis_Homo sapiens_hsa001001.35043742
42Fatty acid metabolism_Homo sapiens_hsa012121.33969471
43Aldosterone synthesis and secretion_Homo sapiens_hsa049251.33631424
44Renin secretion_Homo sapiens_hsa049241.31619654
45Proteasome_Homo sapiens_hsa030501.25587133
46Gastric acid secretion_Homo sapiens_hsa049711.23307122
47Folate biosynthesis_Homo sapiens_hsa007901.23148600
48Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010401.23040398
49Tryptophan metabolism_Homo sapiens_hsa003801.22467569
50Protein processing in endoplasmic reticulum_Homo sapiens_hsa041411.22100811
51Homologous recombination_Homo sapiens_hsa034401.19806596
52Peroxisome_Homo sapiens_hsa041461.19015310
53Neuroactive ligand-receptor interaction_Homo sapiens_hsa040801.11382881
54Thyroid hormone synthesis_Homo sapiens_hsa049181.11233087
55Cardiac muscle contraction_Homo sapiens_hsa042601.09520775
56Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006301.08653603
57Fanconi anemia pathway_Homo sapiens_hsa034601.06667753
58Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042611.06652531
59Carbohydrate digestion and absorption_Homo sapiens_hsa049731.02531736
60Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006031.01583944
61Pancreatic secretion_Homo sapiens_hsa049720.99725194
62Primary bile acid biosynthesis_Homo sapiens_hsa001200.97517886
63Sulfur relay system_Homo sapiens_hsa041220.95346056
64Estrogen signaling pathway_Homo sapiens_hsa049150.95281580
65Calcium signaling pathway_Homo sapiens_hsa040200.94295418
66Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049640.93463048
67Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.92957075
68SNARE interactions in vesicular transport_Homo sapiens_hsa041300.92672585
69Gap junction_Homo sapiens_hsa045400.91884516
70Huntingtons disease_Homo sapiens_hsa050160.90756645
71Glucagon signaling pathway_Homo sapiens_hsa049220.88306561
72Ether lipid metabolism_Homo sapiens_hsa005650.87698763
73cAMP signaling pathway_Homo sapiens_hsa040240.86335354
74Oxytocin signaling pathway_Homo sapiens_hsa049210.85674740
75Butanoate metabolism_Homo sapiens_hsa006500.84933197
76Purine metabolism_Homo sapiens_hsa002300.83055820
77Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047500.82856801
78Fatty acid degradation_Homo sapiens_hsa000710.82742509
79beta-Alanine metabolism_Homo sapiens_hsa004100.81757412
80Circadian rhythm_Homo sapiens_hsa047100.81573428
81RNA degradation_Homo sapiens_hsa030180.81230590
82Vascular smooth muscle contraction_Homo sapiens_hsa042700.81144610
83GnRH signaling pathway_Homo sapiens_hsa049120.79909720
84Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009700.79749108
85cGMP-PKG signaling pathway_Homo sapiens_hsa040220.75984816
86Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049320.75431860
87Metabolic pathways_Homo sapiens_hsa011000.75319389
88Regulation of autophagy_Homo sapiens_hsa041400.74038234
89Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030080.73526443
90Lysosome_Homo sapiens_hsa041420.73136225
91Pyrimidine metabolism_Homo sapiens_hsa002400.73023823
92Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049600.72716348
93Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.70453700
94Taurine and hypotaurine metabolism_Homo sapiens_hsa004300.70359025
95Cysteine and methionine metabolism_Homo sapiens_hsa002700.70275309
96Prion diseases_Homo sapiens_hsa050200.69637033
97Mismatch repair_Homo sapiens_hsa034300.68746113
98Non-homologous end-joining_Homo sapiens_hsa034500.68056877
99Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.66489391
100Rheumatoid arthritis_Homo sapiens_hsa053230.66174783
101Melanogenesis_Homo sapiens_hsa049160.65911194
102Glutathione metabolism_Homo sapiens_hsa004800.65609295
103N-Glycan biosynthesis_Homo sapiens_hsa005100.65432631
104Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005340.65317501
105Phototransduction_Homo sapiens_hsa047440.64446683
106Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.63058950
107Caffeine metabolism_Homo sapiens_hsa002320.62215914
108Alcoholism_Homo sapiens_hsa050340.59287512
109Phosphatidylinositol signaling system_Homo sapiens_hsa040700.57355690
110Linoleic acid metabolism_Homo sapiens_hsa005910.56316386
111Ascorbate and aldarate metabolism_Homo sapiens_hsa000530.56219479
112Oocyte meiosis_Homo sapiens_hsa041140.55329054
113Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.54472440
114Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.53821627
115Phagosome_Homo sapiens_hsa041450.51971688
116alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.51706452
117One carbon pool by folate_Homo sapiens_hsa006700.51685377
118Steroid hormone biosynthesis_Homo sapiens_hsa001400.48928822
119Drug metabolism - cytochrome P450_Homo sapiens_hsa009820.46999185
120Retinol metabolism_Homo sapiens_hsa008300.46961356
121Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.43556942
122ErbB signaling pathway_Homo sapiens_hsa040120.43381052
123Mineral absorption_Homo sapiens_hsa049780.42605096
124Ovarian steroidogenesis_Homo sapiens_hsa049130.41470362
125ABC transporters_Homo sapiens_hsa020100.40448531
126Dilated cardiomyopathy_Homo sapiens_hsa054140.40376065
127Pentose and glucuronate interconversions_Homo sapiens_hsa000400.40329307
128Nucleotide excision repair_Homo sapiens_hsa034200.40133351
129Insulin signaling pathway_Homo sapiens_hsa049100.38528585
130Chemical carcinogenesis_Homo sapiens_hsa052040.37985299
131Dorso-ventral axis formation_Homo sapiens_hsa043200.37818995
132Hedgehog signaling pathway_Homo sapiens_hsa043400.36721400
133Glycerolipid metabolism_Homo sapiens_hsa005610.33916482
134Phenylalanine metabolism_Homo sapiens_hsa003600.33755103
135Sphingolipid metabolism_Homo sapiens_hsa006000.30589398
136Bile secretion_Homo sapiens_hsa049760.29790257
137Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.29557906
138MAPK signaling pathway_Homo sapiens_hsa040100.29526120
139Butirosin and neomycin biosynthesis_Homo sapiens_hsa005240.28796590
140Axon guidance_Homo sapiens_hsa043600.28565486
141Fatty acid elongation_Homo sapiens_hsa000620.26507235
142Inositol phosphate metabolism_Homo sapiens_hsa005620.26467930
143Selenocompound metabolism_Homo sapiens_hsa004500.26130342
144Galactose metabolism_Homo sapiens_hsa000520.26057915
145Pyruvate metabolism_Homo sapiens_hsa006200.25711924
146Prolactin signaling pathway_Homo sapiens_hsa049170.25421341
147Ras signaling pathway_Homo sapiens_hsa040140.25114712
148Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.25021707
149Glioma_Homo sapiens_hsa052140.24818529
150Glycerophospholipid metabolism_Homo sapiens_hsa005640.24309493
151Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.24133267
152Tyrosine metabolism_Homo sapiens_hsa003500.23175893
153Synthesis and degradation of ketone bodies_Homo sapiens_hsa000720.22975479

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