SLC35B1

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: This gene encodes a nucleotide sugar transporter which is a member of solute carrier family 35. The transporters in this family are highly conserved hydrophobic proteins with multiple transmembrane domains. Alternative splicing results in multiple transcript variants encoding different isoforms. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1signal peptide processing (GO:0006465)7.84557178
2COPI coating of Golgi vesicle (GO:0048205)6.71873901
3Golgi transport vesicle coating (GO:0048200)6.71873901
4protein maturation by protein folding (GO:0022417)6.20168492
5GDP-mannose metabolic process (GO:0019673)6.00829615
6maintenance of protein localization in endoplasmic reticulum (GO:0035437)5.50599722
7proteasome assembly (GO:0043248)5.27349617
8ER overload response (GO:0006983)5.08058630
9cullin deneddylation (GO:0010388)5.07985517
10COPII vesicle coating (GO:0048208)4.84647951
11establishment of protein localization to mitochondrial membrane (GO:0090151)4.74909014
12negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436)4.61933776
13protein deneddylation (GO:0000338)4.60694823
14protein retention in ER lumen (GO:0006621)4.60483239
15polyketide metabolic process (GO:0030638)4.57119672
16doxorubicin metabolic process (GO:0044598)4.57119672
17daunorubicin metabolic process (GO:0044597)4.57119672
18energy coupled proton transport, down electrochemical gradient (GO:0015985)4.41310040
19ATP synthesis coupled proton transport (GO:0015986)4.41310040
20positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051437)4.40524343
21endocrine pancreas development (GO:0031018)4.39441903
22regulation of cellular amino acid metabolic process (GO:0006521)4.36106536
23regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051439)4.28566578
24regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway (GO:19022354.26654074
25mitochondrial ATP synthesis coupled proton transport (GO:0042776)4.24857242
26glandular epithelial cell differentiation (GO:0002067)4.23717410
27negative regulation of ubiquitin-protein transferase activity (GO:0051444)4.20688905
28negative regulation of ligase activity (GO:0051352)4.20688905
29cytochrome complex assembly (GO:0017004)4.18311107
30DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest (GO:004.16122367
31RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394)4.14791191
32tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388)4.14791191
33anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process (GO:04.08358610
34signal transduction involved in mitotic DNA integrity checkpoint (GO:1902403)4.06845508
35signal transduction involved in mitotic DNA damage checkpoint (GO:1902402)4.06845508
36signal transduction involved in mitotic cell cycle checkpoint (GO:0072413)4.06845508
37intracellular signal transduction involved in G1 DNA damage checkpoint (GO:1902400)4.04367641
38signal transduction involved in mitotic G1 DNA damage checkpoint (GO:0072431)4.04367641
39peptide hormone processing (GO:0016486)4.03223951
40signal transduction involved in DNA integrity checkpoint (GO:0072401)3.91570543
41signal transduction involved in DNA damage checkpoint (GO:0072422)3.91570543
42signal transduction involved in cell cycle checkpoint (GO:0072395)3.88318356
43sequestering of metal ion (GO:0051238)3.87202328
44dolichol-linked oligosaccharide biosynthetic process (GO:0006488)3.79550384
45positive regulation of ubiquitin-protein transferase activity (GO:0051443)3.79501900
46cytidine deamination (GO:0009972)3.77287773
47cytidine metabolic process (GO:0046087)3.77287773
48cytidine catabolic process (GO:0006216)3.77287773
49mitochondrial electron transport, NADH to ubiquinone (GO:0006120)3.74751860
50nucleotide-sugar biosynthetic process (GO:0009226)3.74541492
51intestinal epithelial cell development (GO:0060576)3.66603034
52quinone metabolic process (GO:1901661)3.66520360
53protein complex biogenesis (GO:0070271)3.66157295
54pseudouridine synthesis (GO:0001522)3.64705845
55positive regulation of ligase activity (GO:0051351)3.61792442
56chaperone-mediated protein transport (GO:0072321)3.60482597
57protein N-linked glycosylation via asparagine (GO:0018279)3.58449372
58termination of RNA polymerase III transcription (GO:0006386)3.58179934
59transcription elongation from RNA polymerase III promoter (GO:0006385)3.58179934
60retrograde vesicle-mediated transport, Golgi to ER (GO:0006890)3.54253142
61peptidyl-asparagine modification (GO:0018196)3.51085369
62exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay 3.43217473
63nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291)3.43013781
64ER-associated ubiquitin-dependent protein catabolic process (GO:0030433)3.40722779
65maintenance of protein localization in organelle (GO:0072595)3.37229591
66regulation of type B pancreatic cell apoptotic process (GO:2000674)3.37056288
67phenol-containing compound catabolic process (GO:0019336)3.34913385
68mitochondrial respiratory chain complex I biogenesis (GO:0097031)3.32878294
69mitochondrial respiratory chain complex I assembly (GO:0032981)3.32878294
70NADH dehydrogenase complex assembly (GO:0010257)3.32878294
71peptidyl-histidine modification (GO:0018202)3.32240191
72protein N-linked glycosylation (GO:0006487)3.32193855
73mitochondrial respiratory chain complex assembly (GO:0033108)3.31791419
74regulation of ubiquitin-protein transferase activity (GO:0051438)3.31385326
75electron transport chain (GO:0022900)3.27587288
76exocrine pancreas development (GO:0031017)3.27339261
77pteridine-containing compound biosynthetic process (GO:0042559)3.25828801
78respiratory electron transport chain (GO:0022904)3.25684970
79hormone catabolic process (GO:0042447)3.25336605
80protein targeting to mitochondrion (GO:0006626)3.24734991
81activation of signaling protein activity involved in unfolded protein response (GO:0006987)3.22340918
82maturation of 5.8S rRNA (GO:0000460)3.21885871
83DNA damage response, detection of DNA damage (GO:0042769)3.18899348
84rRNA methylation (GO:0031167)3.18807584
85regulation of ligase activity (GO:0051340)3.18572449
86protein K6-linked ubiquitination (GO:0085020)3.18182349
87regulation of cilium movement (GO:0003352)3.18109512
88regulation of cellular amine metabolic process (GO:0033238)3.17680999
89rRNA modification (GO:0000154)3.16921266
90DNA damage response, signal transduction by p53 class mediator (GO:0030330)3.15568932
91guanosine-containing compound biosynthetic process (GO:1901070)3.15213340
92cell redox homeostasis (GO:0045454)3.13219647
93coenzyme catabolic process (GO:0009109)3.12706657
94water-soluble vitamin biosynthetic process (GO:0042364)3.12397465
95L-methionine salvage (GO:0071267)3.10627918
96L-methionine biosynthetic process (GO:0071265)3.10627918
97amino acid salvage (GO:0043102)3.10627918
98GTP biosynthetic process (GO:0006183)3.10513669
99establishment of protein localization to mitochondrion (GO:0072655)3.09558717
100positive regulation of cell cycle arrest (GO:0071158)3.08490439
101protein localization to mitochondrion (GO:0070585)3.07812219
102positive regulation of nuclease activity (GO:0032075)3.07563890
103ubiquinone biosynthetic process (GO:0006744)3.05847710
104branched-chain amino acid catabolic process (GO:0009083)3.04477533
105L-methionine biosynthetic process from methylthioadenosine (GO:0019509)3.03921827
106protein-cofactor linkage (GO:0018065)3.01034165
107mannosylation (GO:0097502)3.00623511
108tRNA processing (GO:0008033)2.99840122
109UDP-N-acetylglucosamine metabolic process (GO:0006047)2.98695679
110ER to Golgi vesicle-mediated transport (GO:0006888)2.97785088
111somite rostral/caudal axis specification (GO:0032525)2.97367155
112negative regulation of protein ubiquitination (GO:0031397)2.95686670
113nucleotide-sugar metabolic process (GO:0009225)2.93881544
114DNA replication checkpoint (GO:0000076)2.92727089
115protein neddylation (GO:0045116)2.92507143
116response to redox state (GO:0051775)2.91884894
117DNA catabolic process, exonucleolytic (GO:0000738)2.91574626
118chromatin remodeling at centromere (GO:0031055)2.90794355
119tRNA metabolic process (GO:0006399)2.90773073
120cellular response to topologically incorrect protein (GO:0035967)2.90462787
121DNA deamination (GO:0045006)2.87833787
122cotranslational protein targeting to membrane (GO:0006613)2.85736352
1233-phosphoadenosine 5-phosphosulfate metabolic process (GO:0050427)2.84284896
124purine ribonucleoside bisphosphate metabolic process (GO:0034035)2.84284896
125cellular response to unfolded protein (GO:0034620)2.83708507
126regulation of mitochondrial translation (GO:0070129)2.83486303
127aminoglycoside antibiotic metabolic process (GO:0030647)2.83232972
128SRP-dependent cotranslational protein targeting to membrane (GO:0006614)2.83118201
129endoplasmic reticulum unfolded protein response (GO:0030968)2.82422970
130UTP biosynthetic process (GO:0006228)2.81719367
131regulation of nuclease activity (GO:0032069)2.81698626
132protein targeting to ER (GO:0045047)2.81626771
133response to misfolded protein (GO:0051788)2.80658274
134fatty acid elongation (GO:0030497)2.80475663
135antigen processing and presentation of peptide antigen via MHC class I (GO:0002474)2.80036182
136response to dietary excess (GO:0002021)2.79850292
137ubiquinone metabolic process (GO:0006743)2.79182139
138respiratory chain complex IV assembly (GO:0008535)2.78985193
139pyrimidine nucleoside triphosphate biosynthetic process (GO:0009148)2.78037087
140CENP-A containing nucleosome assembly (GO:0034080)2.77863316
141spliceosomal snRNP assembly (GO:0000387)2.77247523
142protein localization to endoplasmic reticulum (GO:0070972)2.75259878
143nucleoside transmembrane transport (GO:1901642)2.74590739
144intracellular protein transmembrane import (GO:0044743)2.74185807
145replication fork processing (GO:0031297)2.74052952
146DNA double-strand break processing (GO:0000729)2.73835050
147response to endoplasmic reticulum stress (GO:0034976)2.72957712
148negative regulation of protein modification by small protein conjugation or removal (GO:1903321)2.72672457
149antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent (GO:2.72312334
150C-terminal protein lipidation (GO:0006501)2.71605675
151regulation of microtubule-based movement (GO:0060632)2.71365125
152regulation of autophagic vacuole assembly (GO:2000785)2.70194105
1537-methylguanosine mRNA capping (GO:0006370)2.68155847
154establishment of protein localization to endoplasmic reticulum (GO:0072599)2.68150613
155regulation of cell cycle arrest (GO:0071156)2.67893863
156tRNA aminoacylation (GO:0043039)2.67639058
157amino acid activation (GO:0043038)2.67639058
158proline biosynthetic process (GO:0006561)2.67492883
159signal transduction in response to DNA damage (GO:0042770)2.67184070
160GPI anchor biosynthetic process (GO:0006506)2.66026201
161purine nucleoside triphosphate biosynthetic process (GO:0009145)2.66019078
162signal transduction involved in regulation of gene expression (GO:0023019)2.65875700
163antigen processing and presentation of exogenous peptide antigen via MHC class I (GO:0042590)2.65351356
164vesicle coating (GO:0006901)2.65247730
165tRNA aminoacylation for protein translation (GO:0006418)2.63239680
166CTP metabolic process (GO:0046036)2.63070283
167ER-nucleus signaling pathway (GO:0006984)2.62887754
168regulation of hexokinase activity (GO:1903299)2.61269437
169regulation of glucokinase activity (GO:0033131)2.61269437
170calcium-mediated signaling using intracellular calcium source (GO:0035584)2.60490712
171muscle organ morphogenesis (GO:0048644)2.58581958

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1NOTCH1_17114293_ChIP-ChIP_T-ALL_Human5.46660145
2* KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human5.40842823
3GABP_17652178_ChIP-ChIP_JURKAT_Human4.58198900
4PDX1_19855005_ChIP-ChIP_MIN6_Mouse4.30504650
5* JARID1A_20064375_ChIP-Seq_MESCs_Mouse3.98264091
6FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse3.87756951
7* EST1_17652178_ChIP-ChIP_JURKAT_Human3.65920261
8CREB1_15753290_ChIP-ChIP_HEK293T_Human3.46781567
9KLF2_18264089_ChIP-ChIP_MESCs_Mouse3.34398698
10KLF5_18264089_ChIP-ChIP_MESCs_Mouse3.34398698
11KLF4_18264089_ChIP-ChIP_MESCs_Mouse3.34398698
12CHD1_19587682_ChIP-ChIP_MESCs_Mouse3.08223522
13* ETS1_20019798_ChIP-Seq_JURKAT_Human2.97603920
14ELF1_17652178_ChIP-ChIP_JURKAT_Human2.63268545
15HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human2.61103199
16HCFC1_20581084_ChIP-Seq_MESCs_Mouse2.37198322
17MYCN_21190229_ChIP-Seq_SHEP-21N_Human2.36899588
18BP1_19119308_ChIP-ChIP_Hs578T_Human2.28863439
19MYC_18555785_ChIP-Seq_MESCs_Mouse2.22010248
20YY1_21170310_ChIP-Seq_MESCs_Mouse2.19416235
21E2F4_17652178_ChIP-ChIP_JURKAT_Human2.19103815
22SRF_21415370_ChIP-Seq_HL-1_Mouse2.13591495
23* MYC_18358816_ChIP-ChIP_MESCs_Mouse2.13568186
24* E2F1_18555785_ChIP-Seq_MESCs_Mouse2.12027962
25DMRT1_21621532_ChIP-ChIP_FETAL_Ovary2.07589398
26FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human2.06999316
27E2F7_22180533_ChIP-Seq_HELA_Human2.04183848
28* DCP1A_22483619_ChIP-Seq_HELA_Human2.01733576
29PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse1.95729347
30ZNF274_21170338_ChIP-Seq_K562_Hela1.95558199
31IRF1_19129219_ChIP-ChIP_H3396_Human1.95153656
32VDR_23849224_ChIP-Seq_CD4+_Human1.91286169
33GABP_19822575_ChIP-Seq_HepG2_Human1.88665664
34THAP11_20581084_ChIP-Seq_MESCs_Mouse1.88511426
35EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse1.86337315
36MYC_19030024_ChIP-ChIP_MESCs_Mouse1.85422555
37ELK1_22589737_ChIP-Seq_MCF10A_Human1.83797726
38CEBPA_23403033_ChIP-Seq_LIVER_Mouse1.82130561
39ELK1_19687146_ChIP-ChIP_HELA_Human1.78323135
40POU5F1_18555785_ChIP-Seq_MESCs_Mouse1.71185750
41* CEBPB_24764292_ChIP-Seq_MC3T3_Mouse1.66360063
42CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human1.66035565
43TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat1.64677951
44* FOXP3_21729870_ChIP-Seq_TREG_Human1.64199121
45MYC_18940864_ChIP-ChIP_HL60_Human1.63763245
46VDR_22108803_ChIP-Seq_LS180_Human1.60986551
47CEBPB_23403033_ChIP-Seq_LIVER_Mouse1.55353943
48SOX9_22984422_ChIP-ChIP_TESTIS_Rat1.49907267
49E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse1.42421365
50SIN3A_21632747_ChIP-Seq_MESCs_Mouse1.41229632
51NOTCH1_21737748_ChIP-Seq_TLL_Human1.36984622
52* BCL3_23251550_ChIP-Seq_MUSCLE_Mouse1.33316584
53* FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse1.33020753
54PADI4_21655091_ChIP-ChIP_MCF-7_Human1.31694893
55TFEB_21752829_ChIP-Seq_HELA_Human1.30775292
56* ZFP42_18358816_ChIP-ChIP_MESCs_Mouse1.30390428
57MYC_19079543_ChIP-ChIP_MESCs_Mouse1.28617231
58XRN2_22483619_ChIP-Seq_HELA_Human1.28194304
59SOX17_20123909_ChIP-Seq_XEN_Mouse1.27751961
60ERG_20887958_ChIP-Seq_HPC-7_Mouse1.27723375
61CRX_20693478_ChIP-Seq_ADULT_RETINA_Mouse1.27515718
62NELFA_20434984_ChIP-Seq_ESCs_Mouse1.23513360
63HNF4A_19761587_ChIP-ChIP_CACO-2_Human1.20047329
64ETS2_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse1.19102381
65MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse1.18421601
66NANOG_18555785_ChIP-Seq_MESCs_Mouse1.14966572
67* PAX6_23342162_ChIP-ChIP_BETA-FORBRAIN-LENS_Mouse1.14194204
68NANOG_18358816_ChIP-ChIP_MESCs_Mouse1.13343642
69TTF2_22483619_ChIP-Seq_HELA_Human1.12438567
70ZFX_18555785_ChIP-Seq_MESCs_Mouse1.11195930
71SOX2_18358816_ChIP-ChIP_MESCs_Mouse1.07960687
72CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human1.06516219
73E2F1_21310950_ChIP-Seq_MCF-7_Human1.05997989
74EWS_26573619_Chip-Seq_HEK293_Human1.04897399
75AR_21909140_ChIP-Seq_LNCAP_Human1.03865238
76EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human1.03480587
77POU5F1_18700969_ChIP-ChIP_MESCs_Mouse1.03254635
78E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human1.02469846
79* SIN3B_21632747_ChIP-Seq_MESCs_Mouse1.00858093
80* MYCN_18555785_ChIP-Seq_MESCs_Mouse0.99724880
81KDM5A_27292631_Chip-Seq_BREAST_Human0.98993217
82PRDM5_23873026_ChIP-Seq_MEFs_Mouse0.98061946
83E2F1_17053090_ChIP-ChIP_MCF-7_Human0.97674971
84EGR1_23403033_ChIP-Seq_LIVER_Mouse0.95404745
85ASH2L_23239880_ChIP-Seq_MESCs_Mouse0.94946241
86HTT_18923047_ChIP-ChIP_STHdh_Human0.94556080
87REST_19997604_ChIP-ChIP_NEURONS_Mouse0.94044335
88POU5F1_18358816_ChIP-ChIP_MESCs_Mouse0.93332679
89MYBL2_22936984_ChIP-ChIP_MESCs_Mouse0.93309552
90SALL1_21062744_ChIP-ChIP_HESCs_Human0.90078328
91ERG_20517297_ChIP-Seq_VCAP_Human0.87904005
92STAT5_23275557_ChIP-Seq_MAMMARY-EPITHELIUM_Mouse0.87148977
93* HOXB4_20404135_ChIP-ChIP_EML_Mouse0.85319173
94FLI1_20887958_ChIP-Seq_HPC-7_Mouse0.84250322
95GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse0.83400438
96FOXA1_27270436_Chip-Seq_PROSTATE_Human0.82185728
97FOXA1_25329375_ChIP-Seq_VCAP_Human0.82185728
98YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse0.82053028
99ELF5_23300383_ChIP-Seq_T47D_Human0.82029855
100FLI1_27457419_Chip-Seq_LIVER_Mouse0.81738399
101KDM5B_21448134_ChIP-Seq_MESCs_Mouse0.81336505
102FUS_26573619_Chip-Seq_HEK293_Human0.80267117
103SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse0.79043202
104NACC1_18358816_ChIP-ChIP_MESCs_Mouse0.78594913
105BMI1_23680149_ChIP-Seq_NPCS_Mouse0.78251833
106* CCND1_20090754_ChIP-ChIP_RETINA_Mouse0.76493494
107ETV2_25802403_ChIP-Seq_MESCs_Mouse0.76262684
108NR4A2_19515692_ChIP-ChIP_MN9D_Mouse0.76152257
109* CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat0.74994918
110* CUX1_19635798_ChIP-ChIP_MULTIPLE_HUMAN_CANCER_TYPES_Human0.74967985
111HOXB7_26014856_ChIP-Seq_BT474_Human0.72885250
112NANOG_16153702_ChIP-ChIP_HESCs_Human0.71813256
113OCT4_18692474_ChIP-Seq_MEFs_Mouse0.71629906
114SOX2_18692474_ChIP-Seq_MEFs_Mouse0.70078879
115TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse0.69758579
116TP53_22573176_ChIP-Seq_HFKS_Human0.69720138
117ZFP57_27257070_Chip-Seq_ESCs_Mouse0.69268617
118* SOX2_27498859_Chip-Seq_STOMACH_Mouse0.69205356
119ESRRB_18555785_ChIP-Seq_MESCs_Mouse0.69043951
120EOMES_21245162_ChIP-Seq_HESCs_Human0.68820211
121SREBP1_19666523_ChIP-Seq_LIVER_Mouse0.68606273
122AR_20517297_ChIP-Seq_VCAP_Human0.68501788
123TCF3_18692474_ChIP-Seq_MEFs_Mouse0.68432871
124RCOR1_19997604_ChIP-ChIP_NEURONS_Mouse0.67805827
125* CTCF_18555785_ChIP-Seq_MESCs_Mouse0.67728095
126EBNA1_20929547_Chip-Seq_RAJI-cells_Human0.67149872
127HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse0.66795081

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0004043_abnormal_pH_regulation4.67515284
2MP0000678_abnormal_parathyroid_gland3.74961124
3MP0003183_abnormal_peptide_metabolism3.50197449
4MP0004264_abnormal_extraembryonic_tissu3.47323601
5MP0003195_calcinosis3.44368120
6MP0008058_abnormal_DNA_repair3.32414172
7MP0002877_abnormal_melanocyte_morpholog3.06997785
8MP0003718_maternal_effect2.89887783
9MP0003806_abnormal_nucleotide_metabolis2.85879784
10MP0010386_abnormal_urinary_bladder2.84126166
11MP0002693_abnormal_pancreas_physiology2.79721736
12MP0003122_maternal_imprinting2.60843766
13MP0003890_abnormal_embryonic-extraembry2.50325089
14MP0003283_abnormal_digestive_organ2.50148506
15MP0002102_abnormal_ear_morphology2.43960412
16MP0005220_abnormal_exocrine_pancreas2.43167624
17MP0001944_abnormal_pancreas_morphology2.40983661
18MP0004147_increased_porphyrin_level2.33194334
19MP0010094_abnormal_chromosome_stability2.31782811
20MP0005379_endocrine/exocrine_gland_phen2.20600598
21MP0003646_muscle_fatigue2.15874965
22MP0006035_abnormal_mitochondrial_morpho2.09587763
23MP0002876_abnormal_thyroid_physiology2.08627642
24MP0006292_abnormal_olfactory_placode2.00641092
25MP0002837_dystrophic_cardiac_calcinosis1.97590737
26MP0000013_abnormal_adipose_tissue1.93984267
27MP0002139_abnormal_hepatobiliary_system1.93691941
28MP0001666_abnormal_nutrient_absorption1.91482044
29MP0005257_abnormal_intraocular_pressure1.90120332
30MP0003786_premature_aging1.88850849
31MP0008877_abnormal_DNA_methylation1.82632738
32MP0006072_abnormal_retinal_apoptosis1.74629279
33MP0003186_abnormal_redox_activity1.73991228
34MP0003011_delayed_dark_adaptation1.68222777
35MP0006036_abnormal_mitochondrial_physio1.65210998
36MP0002736_abnormal_nociception_after1.65177496
37MP0002277_abnormal_respiratory_mucosa1.64613261
38MP0005394_taste/olfaction_phenotype1.63412329
39MP0005499_abnormal_olfactory_system1.63412329
40MP0002638_abnormal_pupillary_reflex1.62176175
41MP0002909_abnormal_adrenal_gland1.57980071
42MP0008872_abnormal_physiological_respon1.56659600
43MP0003077_abnormal_cell_cycle1.55425939
44MP0008007_abnormal_cellular_replicative1.55137457
45MP0002078_abnormal_glucose_homeostasis1.52775900
46MP0002163_abnormal_gland_morphology1.48584400
47MP0005365_abnormal_bile_salt1.47807949
48MP0003111_abnormal_nucleus_morphology1.46993215
49MP0000427_abnormal_hair_cycle1.38480976
50MP0005551_abnormal_eye_electrophysiolog1.37981517
51MP0005408_hypopigmentation1.37904998
52MP0009379_abnormal_foot_pigmentation1.36929046
53MP0003868_abnormal_feces_composition1.36335758
54MP0004957_abnormal_blastocyst_morpholog1.36335541
55MP0001529_abnormal_vocalization1.31798962
56MP0009046_muscle_twitch1.31375766
57MP0009780_abnormal_chondrocyte_physiolo1.29210267
58MP0005636_abnormal_mineral_homeostasis1.28431350
59MP0001968_abnormal_touch/_nociception1.28417296
60MP0008789_abnormal_olfactory_epithelium1.25664938
61MP0003136_yellow_coat_color1.24906587
62MP0005360_urolithiasis1.24849177
63MP0002160_abnormal_reproductive_system1.24237659
64MP0009643_abnormal_urine_homeostasis1.21195502
65MP0002090_abnormal_vision1.20504058
66MP0002210_abnormal_sex_determination1.18877946
67MP0004782_abnormal_surfactant_physiolog1.17618209
68MP0000462_abnormal_digestive_system1.17590968
69MP0005646_abnormal_pituitary_gland1.17299543
70MP0005389_reproductive_system_phenotype1.17022636
71MP0001764_abnormal_homeostasis1.16180163
72MP0002295_abnormal_pulmonary_circulatio1.16052801
73MP0002254_reproductive_system_inflammat1.15616255
74MP0000613_abnormal_salivary_gland1.15399767
75MP0000749_muscle_degeneration1.13301302
76MP0001919_abnormal_reproductive_system1.10428185
77MP0005058_abnormal_lysosome_morphology1.07489347
78MP0003123_paternal_imprinting1.06690872
79MP0001929_abnormal_gametogenesis1.05552504
80MP0005266_abnormal_metabolism1.04267338
81MP0001905_abnormal_dopamine_level1.03897506
82MP0000049_abnormal_middle_ear1.02529731
83MP0001542_abnormal_bone_strength1.01651831
84MP0002234_abnormal_pharynx_morphology1.00452319
85MP0005395_other_phenotype1.00359436
86MP0000538_abnormal_urinary_bladder0.98954351
87MP0000358_abnormal_cell_content/0.98609404
88MP0005084_abnormal_gallbladder_morpholo0.98223659
89MP0005083_abnormal_biliary_tract0.97741442
90MP0005085_abnormal_gallbladder_physiolo0.97252226
91MP0004858_abnormal_nervous_system0.96537163
92MP0002095_abnormal_skin_pigmentation0.96241541
93MP0008875_abnormal_xenobiotic_pharmacok0.96028189
94MP0002751_abnormal_autonomic_nervous0.95763746
95MP0003693_abnormal_embryo_hatching0.94714340
96MP0005376_homeostasis/metabolism_phenot0.94534647
97MP0000372_irregular_coat_pigmentation0.93067260
98MP0000653_abnormal_sex_gland0.92003820
99MP0005075_abnormal_melanosome_morpholog0.91613666
100MP0006082_CNS_inflammation0.90565144
101MP0005253_abnormal_eye_physiology0.90520249
102MP0004019_abnormal_vitamin_homeostasis0.89989657
103MP0001145_abnormal_male_reproductive0.87759554
104MP0001293_anophthalmia0.87629684
105MP0003950_abnormal_plasma_membrane0.87199810
106MP0002653_abnormal_ependyma_morphology0.87176369
107MP0003953_abnormal_hormone_level0.86592627
108MP0005310_abnormal_salivary_gland0.86424806
109MP0004215_abnormal_myocardial_fiber0.86334492
110MP0004133_heterotaxia0.86089168
111MP0004142_abnormal_muscle_tone0.86021230
112MP0003119_abnormal_digestive_system0.84765269
113MP0005410_abnormal_fertilization0.84594422
114MP0001984_abnormal_olfaction0.84418112
115MP0000647_abnormal_sebaceous_gland0.84400979
116MP0001727_abnormal_embryo_implantation0.83410043
117MP0000516_abnormal_urinary_system0.82668837
118MP0005367_renal/urinary_system_phenotyp0.82668837
119MP0001986_abnormal_taste_sensitivity0.81821640
120MP0000762_abnormal_tongue_morphology0.81698402
121MP0002332_abnormal_exercise_endurance0.81598859
122MP0001661_extended_life_span0.80402344
123MP0001756_abnormal_urination0.80073379
124MP0001765_abnormal_ion_homeostasis0.79487983
125MP0003937_abnormal_limbs/digits/tail_de0.79280441
126MP0003121_genomic_imprinting0.78935213
127MP0002938_white_spotting0.77651941
128MP0005645_abnormal_hypothalamus_physiol0.77628214
129MP0001664_abnormal_digestion0.77439379
130MP0005332_abnormal_amino_acid0.77437513
131MP0002734_abnormal_mechanical_nocicepti0.77226701
132MP0008932_abnormal_embryonic_tissue0.77046303
133MP0003959_abnormal_lean_body0.76694026
134MP0000631_abnormal_neuroendocrine_gland0.76030651
135MP0004381_abnormal_hair_follicle0.73155514
136MP0006276_abnormal_autonomic_nervous0.73026176
137MP0002098_abnormal_vibrissa_morphology0.72923930
138MP0002127_abnormal_cardiovascular_syste0.72888489
139MP0001119_abnormal_female_reproductive0.72864083
140MP0005319_abnormal_enzyme/_coenzyme0.72791245
141MP0003698_abnormal_male_reproductive0.72482847
142MP0009697_abnormal_copulation0.72378045
143MP0010030_abnormal_orbit_morphology0.70518836
144MP0000681_abnormal_thyroid_gland0.70289842
145MP0005174_abnormal_tail_pigmentation0.69850761
146MP0000003_abnormal_adipose_tissue0.68853494
147MP0004270_analgesia0.68668940
148MP0002229_neurodegeneration0.68658696
149MP0003252_abnormal_bile_duct0.67398558
150MP0001324_abnormal_eye_pigmentation0.62874355
151MP0008775_abnormal_heart_ventricle0.61927114

Predicted human phenotypes

RankGene SetZ-score
1Hyperinsulinemic hypoglycemia (HP:0000825)5.75872651
2Type I transferrin isoform profile (HP:0003642)4.48167024
3Acute necrotizing encephalopathy (HP:0006965)4.39812240
4Symptomatic seizures (HP:0011145)3.99478836
5Abnormal mitochondria in muscle tissue (HP:0008316)3.99046065
6Hypoglycemic coma (HP:0001325)3.79300078
7Abnormal isoelectric focusing of serum transferrin (HP:0003160)3.77603318
8Abnormal protein N-linked glycosylation (HP:0012347)3.77603318
9Abnormal protein glycosylation (HP:0012346)3.77603318
10Abnormal glycosylation (HP:0012345)3.77603318
11Hypoglycemic seizures (HP:0002173)3.77057713
12Abnormality of the intrinsic pathway (HP:0010989)3.72197349
13Acute encephalopathy (HP:0006846)3.66362593
14Progressive macrocephaly (HP:0004481)3.51278173
15Reduced antithrombin III activity (HP:0001976)3.36333362
16Abnormality of glycolysis (HP:0004366)3.33182504
17Increased serum pyruvate (HP:0003542)3.33182504
18Abnormal activity of mitochondrial respiratory chain (HP:0011922)3.31282207
19Decreased activity of mitochondrial respiratory chain (HP:0008972)3.31282207
20Mitochondrial inheritance (HP:0001427)3.29967747
21Aplasia/Hypoplasia of the fovea (HP:0008060)3.19143065
22Hypoplasia of the fovea (HP:0007750)3.19143065
23Generalized aminoaciduria (HP:0002909)3.15322909
24Abnormality of aromatic amino acid family metabolism (HP:0004338)2.99258753
25Hepatic necrosis (HP:0002605)2.96693985
26Abnormal pancreas size (HP:0012094)2.94761378
27Increased CSF lactate (HP:0002490)2.92941755
28Microvesicular hepatic steatosis (HP:0001414)2.90490515
29Increased intramyocellular lipid droplets (HP:0012240)2.81339160
30Bifid tongue (HP:0010297)2.80112223
31Multiple enchondromatosis (HP:0005701)2.79646124
32Hepatoblastoma (HP:0002884)2.75472253
33Abnormality of the fovea (HP:0000493)2.71002785
343-Methylglutaconic aciduria (HP:0003535)2.70698509
35Elevated circulating parathyroid hormone (PTH) level (HP:0003165)2.68940900
36Abnormality of endocrine pancreas physiology (HP:0012093)2.67972689
37Abnormality of the pancreatic islet cells (HP:0006476)2.67972689
38Bilateral microphthalmos (HP:0007633)2.67254342
39Renal Fanconi syndrome (HP:0001994)2.61721325
40Ketoacidosis (HP:0001993)2.61491918
41Meckel diverticulum (HP:0002245)2.60066088
42Pancreatic cysts (HP:0001737)2.58563663
43Chromosomal breakage induced by crosslinking agents (HP:0003221)2.56400630
44Optic disc pallor (HP:0000543)2.53781839
45Abnormality of the ileum (HP:0001549)2.53280602
46Pancreatic islet-cell hyperplasia (HP:0004510)2.52539148
47Cerebral edema (HP:0002181)2.49347630
48Glycosuria (HP:0003076)2.48141366
49Abnormality of urine glucose concentration (HP:0011016)2.48141366
50Hepatocellular necrosis (HP:0001404)2.45411571
51Hyperglycemia (HP:0003074)2.44354138
52Gout (HP:0001997)2.40416756
53CNS demyelination (HP:0007305)2.40080063
54Abnormal pupillary function (HP:0007686)2.38170420
55Dysautonomia (HP:0002459)2.37092218
56Aplasia/Hypoplasia of the uvula (HP:0010293)2.36123664
57Aplasia/hypoplasia of the uterus (HP:0008684)2.34485511
58Pancreatic fibrosis (HP:0100732)2.33868376
59Abnormality of alanine metabolism (HP:0010916)2.33133737
60Hyperalaninemia (HP:0003348)2.33133737
61Abnormality of pyruvate family amino acid metabolism (HP:0010915)2.33133737
62Vacuolated lymphocytes (HP:0001922)2.30751899
63Abnormality of the preputium (HP:0100587)2.30006372
64Increased muscle lipid content (HP:0009058)2.29964215
65Exertional dyspnea (HP:0002875)2.29587802
66Conjugated hyperbilirubinemia (HP:0002908)2.29131519
67Hypokinesia (HP:0002375)2.25279038
68Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688)2.25042148
69Hyperphosphaturia (HP:0003109)2.24440900
70Type 2 muscle fiber atrophy (HP:0003554)2.24349465
71Progressive muscle weakness (HP:0003323)2.23907246
72Respiratory difficulties (HP:0002880)2.22136226
73Osteomalacia (HP:0002749)2.21845856
74Abnormality of calcium-phosphate metabolism (HP:0100530)2.21606248
75Abnormality of liposaccharide metabolism (HP:0010968)2.21156720
76Abnormality of glycosphingolipid metabolism (HP:0004343)2.21156720
77Abnormality of glycolipid metabolism (HP:0010969)2.21156720
78Chromsome breakage (HP:0040012)2.20856201
79Methylmalonic aciduria (HP:0012120)2.19790892
80Exercise intolerance (HP:0003546)2.18413334
81Cortical visual impairment (HP:0100704)2.16931159
82Testicular atrophy (HP:0000029)2.16755957
83Pendular nystagmus (HP:0012043)2.15208810
84Molar tooth sign on MRI (HP:0002419)2.15205045
85Abnormality of midbrain morphology (HP:0002418)2.15205045
86Hyperglycinemia (HP:0002154)2.14559282
87Cerebral hypomyelination (HP:0006808)2.09607374
88Insulin-resistant diabetes mellitus (HP:0000831)2.09493098
89Methylmalonic acidemia (HP:0002912)2.08789175
90Poor head control (HP:0002421)2.07516872
91Ragged-red muscle fibers (HP:0003200)2.06123817
92Opisthotonus (HP:0002179)2.05296492
93Respiratory failure (HP:0002878)2.05130920
94Trismus (HP:0000211)2.04740021
95True hermaphroditism (HP:0010459)2.04637867
96Pheochromocytoma (HP:0002666)2.03382251
97Late onset (HP:0003584)2.01364168
98Aplasia/Hypoplasia involving the musculature (HP:0001460)1.97716328
99Nephronophthisis (HP:0000090)1.97148597
100Leukodystrophy (HP:0002415)1.97130542
101Neuroendocrine neoplasm (HP:0100634)1.96547515
102Large for gestational age (HP:0001520)1.96462485
103X-linked dominant inheritance (HP:0001423)1.96299582
104Increased hepatocellular lipid droplets (HP:0006565)1.95531537
105Dysostosis multiplex (HP:0000943)1.95221123
106Muscle fiber atrophy (HP:0100295)1.95131231
107Reticulocytopenia (HP:0001896)1.93344996
108Increased serum lactate (HP:0002151)1.92851505
109Abnormality of serum amino acid levels (HP:0003112)1.92030535
110Secondary amenorrhea (HP:0000869)1.92022152
111Medial flaring of the eyebrow (HP:0010747)1.91133546
112Sensory axonal neuropathy (HP:0003390)1.90983418
113Hypoplasia of the uterus (HP:0000013)1.90134653
114Abnormality of renal resorption (HP:0011038)1.88686889
115Emotional lability (HP:0000712)1.87426918
116Lipid accumulation in hepatocytes (HP:0006561)1.87403378
117Abnormality of the pons (HP:0007361)1.86233268
118Hyperparathyroidism (HP:0000843)1.85262566
119CNS hypomyelination (HP:0003429)1.85250809
120Abnormal autonomic nervous system physiology (HP:0012332)1.83541725
121Congenital primary aphakia (HP:0007707)1.81700876
122Congenital nonbullous ichthyosiform erythroderma (HP:0007479)1.81472454
123Lethargy (HP:0001254)1.80966393
124Facial cleft (HP:0002006)1.80578178
125Abnormality of methionine metabolism (HP:0010901)1.79506253
126Abnormal cartilage morphology (HP:0002763)1.78988907
127Hypothermia (HP:0002045)1.78940669
128Pancytopenia (HP:0001876)1.78437100
129Gait imbalance (HP:0002141)1.78012535
130Blindness (HP:0000618)1.77649687
131Muscle abnormality related to mitochondrial dysfunction (HP:0003800)1.77395811
132Upper limb muscle weakness (HP:0003484)1.77312498
133Chronic bronchitis (HP:0004469)1.77251031
134Abdominal distention (HP:0003270)1.77005781
135Delayed CNS myelination (HP:0002188)1.76995524
136Absent thumb (HP:0009777)1.75399522
137Amniotic constriction ring (HP:0009775)1.75272811
138Abnormality of placental membranes (HP:0011409)1.75272811
139Abnormality of glycine metabolism (HP:0010895)1.75236864
140Abnormality of serine family amino acid metabolism (HP:0010894)1.75236864
141Abnormality of chromosome stability (HP:0003220)1.74833380
142Abnormal hemoglobin (HP:0011902)1.74424986
143Progressive microcephaly (HP:0000253)1.74385079
144Abnormality of small intestinal villus morphology (HP:0011472)1.74002577
145Villous atrophy (HP:0011473)1.74002577
146Abnormality of aspartate family amino acid metabolism (HP:0010899)1.73106787
147Dicarboxylic aciduria (HP:0003215)1.72237157
148Abnormality of dicarboxylic acid metabolism (HP:0010995)1.72237157
149Lactic acidosis (HP:0003128)1.72195451
150Aplasia/Hypoplasia affecting the retina (HP:0008061)1.71803755
151Hyperglycinuria (HP:0003108)1.71263476
152Sclerocornea (HP:0000647)1.70702915
153Oral leukoplakia (HP:0002745)1.68456986
154Degeneration of anterior horn cells (HP:0002398)1.64336473
155Abnormality of the anterior horn cell (HP:0006802)1.64336473
156Duodenal stenosis (HP:0100867)1.63603691
157Small intestinal stenosis (HP:0012848)1.63603691
158Sparse eyelashes (HP:0000653)1.63544376

Predicted kinase interactions (KEA)

RankGene SetZ-score
1ERN14.67834419
2INSRR3.44410695
3VRK23.20537646
4PASK3.17024742
5AKT33.01806987
6EIF2AK32.99890143
7GRK52.97769590
8BCKDK2.63469869
9STK162.59298176
10MAPK152.44378194
11NME12.42604908
12NUAK12.36048145
13TRIM282.35074033
14NME22.32835926
15ADRBK22.26845663
16MAP4K22.23556621
17BRAF2.04006372
18GRK72.00525817
19MAP3K122.00468408
20FRK1.89144288
21GRK11.83783392
22WNK41.83588016
23ARAF1.76570358
24CDK121.75256425
25EPHA21.73889199
26BUB11.67917055
27MAPKAPK31.65619930
28BMPR1B1.63087588
29MUSK1.61485271
30NTRK11.54877588
31HIPK21.51901767
32CDC71.48917606
33NEK11.47560174
34IRAK31.45490560
35PBK1.44842795
36MST41.44209893
37MAP2K21.38364681
38GRK61.37423945
39VRK11.36349147
40PRKD31.29994080
41BCR1.28888342
42ACVR1B1.28071895
43WEE11.26485856
44DYRK21.24337329
45TESK11.24212379
46LIMK11.22022156
47MET1.17689655
48MKNK21.15267772
49MOS1.10560525
50PHKG11.06819493
51PHKG21.06819493
52MAP3K31.05242845
53CSNK1G11.03702602
54EIF2AK11.03597621
55PIM21.03277054
56MAP3K21.02254324
57STK391.02045491
58ADRBK11.00231737
59BMPR20.98939758
60PRKG20.95390109
61UHMK10.91028773
62PRKCI0.89948337
63WNK10.88451478
64MAPK70.87052956
65TESK20.86994191
66OXSR10.85922771
67BRSK10.83806721
68PNCK0.82654949
69WNK30.82163725
70CASK0.80517830
71PINK10.80398274
72PIK3CG0.79569419
73CDK80.79240016
74IRAK10.79140941
75CSNK1G20.77763537
76TAF10.74957309
77DAPK10.74113860
78PAK30.72963522
79CAMK2B0.70569413
80AURKA0.69776290
81TTK0.69483017
82FER0.68065665
83TNIK0.65351228
84ABL20.65157858
85MAP2K60.62125814
86EIF2AK20.61650755
87CSF1R0.61198637
88MAP2K70.60390874
89MAPK130.60052797
90CAMK2D0.59941814
91PRKCG0.59941509
92CSNK1A1L0.59782972
93MKNK10.59364014
94PRKCE0.58578151
95CSNK1A10.58309519
96DYRK30.57725712
97PAK40.57094353
98CCNB10.56276703
99TAOK30.54556579
100IRAK40.53729637
101ATR0.53665177
102STK30.53211475
103MAPKAPK50.52848280
104PTK20.52835790
105AURKB0.52731726
106ILK0.51931634
107MST1R0.50712322
108LATS10.49772614
109TLK10.48629510
110IRAK20.46638739
111CDC42BPA0.45781288
112CSNK2A20.45755187
113CSNK1G30.45745361
114CHEK20.45333383
115ZAK0.45171853
116OBSCN0.44079712
117PAK10.43595140
118TSSK60.43351484
119MYLK0.43179101
120PRKACA0.41062967
121CSNK2A10.39654275
122BRSK20.39442585
123DYRK1A0.37932844
124CAMK2G0.37810422
125SRPK10.37200296
126IGF1R0.36620091
127FLT30.34931711
128PLK40.34628147
129ERBB40.33914613
130DYRK1B0.33633520
131PLK10.33506915
132ERBB30.33032192
133RPS6KA50.32547460
134MATK0.31777359
135RPS6KB20.31729699
136PRKCD0.29499960
137ATM0.28686143
138PLK20.27706025
139PDK20.27460416
140GSK3A0.27341004
141STK38L0.27079960
142MAP3K40.27076645
143PLK30.26806838

Predicted pathways (KEGG)

RankGene SetZ-score
1Protein export_Homo sapiens_hsa030606.80702421
2Maturity onset diabetes of the young_Homo sapiens_hsa049505.18961489
3Sulfur metabolism_Homo sapiens_hsa009203.40434346
4Oxidative phosphorylation_Homo sapiens_hsa001903.16872834
5Proteasome_Homo sapiens_hsa030502.75745746
6Protein processing in endoplasmic reticulum_Homo sapiens_hsa041412.65998142
7Parkinsons disease_Homo sapiens_hsa050122.41177227
8Vibrio cholerae infection_Homo sapiens_hsa051102.19117919
9Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006032.14361659
10Folate biosynthesis_Homo sapiens_hsa007902.14008639
11Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001302.02980369
12Mismatch repair_Homo sapiens_hsa034302.02894180
13Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005201.95955253
14DNA replication_Homo sapiens_hsa030301.87789517
15Terpenoid backbone biosynthesis_Homo sapiens_hsa009001.87397269
16Vitamin B6 metabolism_Homo sapiens_hsa007501.82887624
17Alzheimers disease_Homo sapiens_hsa050101.82794801
18Fanconi anemia pathway_Homo sapiens_hsa034601.73719778
19Steroid biosynthesis_Homo sapiens_hsa001001.71749373
20N-Glycan biosynthesis_Homo sapiens_hsa005101.69682104
21Huntingtons disease_Homo sapiens_hsa050161.68335239
22Fatty acid elongation_Homo sapiens_hsa000621.65605500
23Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049321.65558252
24Linoleic acid metabolism_Homo sapiens_hsa005911.58484124
25Ribosome_Homo sapiens_hsa030101.58447598
26RNA polymerase_Homo sapiens_hsa030201.56826226
27Propanoate metabolism_Homo sapiens_hsa006401.56656859
28Galactose metabolism_Homo sapiens_hsa000521.47573730
29Base excision repair_Homo sapiens_hsa034101.42576495
30Other glycan degradation_Homo sapiens_hsa005111.40408633
31Fructose and mannose metabolism_Homo sapiens_hsa000511.38357976
32Arachidonic acid metabolism_Homo sapiens_hsa005901.38228177
33Collecting duct acid secretion_Homo sapiens_hsa049661.35942132
34alpha-Linolenic acid metabolism_Homo sapiens_hsa005921.33791187
35Nucleotide excision repair_Homo sapiens_hsa034201.33185711
36Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005631.32652503
37Regulation of autophagy_Homo sapiens_hsa041401.25055701
38Non-homologous end-joining_Homo sapiens_hsa034501.23575569
392-Oxocarboxylic acid metabolism_Homo sapiens_hsa012101.11257044
40Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009701.08306576
41Valine, leucine and isoleucine degradation_Homo sapiens_hsa002801.07821023
42Citrate cycle (TCA cycle)_Homo sapiens_hsa000201.06423068
43Ether lipid metabolism_Homo sapiens_hsa005651.04552813
44Selenocompound metabolism_Homo sapiens_hsa004501.04333890
45Caffeine metabolism_Homo sapiens_hsa002321.04134909
46Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030081.03133556
47Lysosome_Homo sapiens_hsa041421.01197114
48Fat digestion and absorption_Homo sapiens_hsa049751.00904513
49Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.97426225
50Sphingolipid metabolism_Homo sapiens_hsa006000.95411283
51Histidine metabolism_Homo sapiens_hsa003400.95380465
52SNARE interactions in vesicular transport_Homo sapiens_hsa041300.92604418
53Tryptophan metabolism_Homo sapiens_hsa003800.90032754
54Synthesis and degradation of ketone bodies_Homo sapiens_hsa000720.87968908
55Pyrimidine metabolism_Homo sapiens_hsa002400.86704349
56Cyanoamino acid metabolism_Homo sapiens_hsa004600.86357365
57Metabolic pathways_Homo sapiens_hsa011000.85985790
58Tyrosine metabolism_Homo sapiens_hsa003500.80249981
59Primary bile acid biosynthesis_Homo sapiens_hsa001200.78960369
60Butanoate metabolism_Homo sapiens_hsa006500.76483126
61Pentose and glucuronate interconversions_Homo sapiens_hsa000400.76347315
62Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.75989601
63Insulin secretion_Homo sapiens_hsa049110.75531903
64Glycosaminoglycan degradation_Homo sapiens_hsa005310.75246196
65Drug metabolism - cytochrome P450_Homo sapiens_hsa009820.74622966
66Phototransduction_Homo sapiens_hsa047440.73590714
67Glutathione metabolism_Homo sapiens_hsa004800.72743635
68Drug metabolism - other enzymes_Homo sapiens_hsa009830.71806322
69Ascorbate and aldarate metabolism_Homo sapiens_hsa000530.70338089
70Phenylalanine metabolism_Homo sapiens_hsa003600.70169311
71Arginine and proline metabolism_Homo sapiens_hsa003300.70150226
72Chemical carcinogenesis_Homo sapiens_hsa052040.69069350
73Cytosolic DNA-sensing pathway_Homo sapiens_hsa046230.68541193
74Type I diabetes mellitus_Homo sapiens_hsa049400.67646970
75Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.64871907
76Fatty acid metabolism_Homo sapiens_hsa012120.63053280
77Butirosin and neomycin biosynthesis_Homo sapiens_hsa005240.63028754
78beta-Alanine metabolism_Homo sapiens_hsa004100.59531637
79Retinol metabolism_Homo sapiens_hsa008300.59389376
80Fatty acid degradation_Homo sapiens_hsa000710.59358998
81Phagosome_Homo sapiens_hsa041450.59245576
82Cell cycle_Homo sapiens_hsa041100.58773481
83Biosynthesis of amino acids_Homo sapiens_hsa012300.58547698
84Peroxisome_Homo sapiens_hsa041460.55676717
85Pancreatic secretion_Homo sapiens_hsa049720.55523218
86Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.53019668
87Cardiac muscle contraction_Homo sapiens_hsa042600.52081213
88Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010400.49696650
89Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.48329577
90Basal transcription factors_Homo sapiens_hsa030220.47762882
91Taurine and hypotaurine metabolism_Homo sapiens_hsa004300.47370561
92Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.47230416
93Starch and sucrose metabolism_Homo sapiens_hsa005000.45417543
94Rheumatoid arthritis_Homo sapiens_hsa053230.43450827
95Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.43189627
96Purine metabolism_Homo sapiens_hsa002300.43006373
97Nitrogen metabolism_Homo sapiens_hsa009100.41691369
98p53 signaling pathway_Homo sapiens_hsa041150.39507628
99Pyruvate metabolism_Homo sapiens_hsa006200.38747552
100Renin-angiotensin system_Homo sapiens_hsa046140.38650989
101Prion diseases_Homo sapiens_hsa050200.34787290
102Vitamin digestion and absorption_Homo sapiens_hsa049770.34164913
103Cocaine addiction_Homo sapiens_hsa050300.34078447
104Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.33988477
105Serotonergic synapse_Homo sapiens_hsa047260.33898501
106Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004000.32855553
107Protein digestion and absorption_Homo sapiens_hsa049740.31989619
108Oocyte meiosis_Homo sapiens_hsa041140.31589373
109RNA transport_Homo sapiens_hsa030130.30996305
110Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006300.30189124
111Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.29851834
112Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.25595896
113Taste transduction_Homo sapiens_hsa047420.24670282
114Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.24361421
115Thyroid hormone synthesis_Homo sapiens_hsa049180.24288335
116Homologous recombination_Homo sapiens_hsa034400.23579676
117RNA degradation_Homo sapiens_hsa030180.22550794
118Carbon metabolism_Homo sapiens_hsa012000.22103045
119One carbon pool by folate_Homo sapiens_hsa006700.21651367
120Steroid hormone biosynthesis_Homo sapiens_hsa001400.20704876
121Cysteine and methionine metabolism_Homo sapiens_hsa002700.18775968
122Legionellosis_Homo sapiens_hsa051340.17362356
123Sulfur relay system_Homo sapiens_hsa041220.15789811
124Vasopressin-regulated water reabsorption_Homo sapiens_hsa049620.15710784
125Pentose phosphate pathway_Homo sapiens_hsa000300.13554840
126Synaptic vesicle cycle_Homo sapiens_hsa047210.13495655
127Spliceosome_Homo sapiens_hsa030400.12044962
128Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.11847605
129Glycerophospholipid metabolism_Homo sapiens_hsa005640.11546642
130Mineral absorption_Homo sapiens_hsa049780.11196284

Most similar genes based on co-expression Upload to Enrichr

Tissue Expression Export image »

Cell Line Expression Export image »