SLC30A9

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1regulation of short-term neuronal synaptic plasticity (GO:0048172)4.68481991
2synaptic vesicle maturation (GO:0016188)4.63106766
3positive regulation of calcium ion-dependent exocytosis (GO:0045956)4.41987605
4neuronal action potential propagation (GO:0019227)4.34883129
5positive regulation of excitatory postsynaptic membrane potential (GO:2000463)4.32403340
6synaptic vesicle exocytosis (GO:0016079)4.01062013
7locomotory exploration behavior (GO:0035641)3.94938621
8neuromuscular process controlling posture (GO:0050884)3.93941013
9regulation of synaptic vesicle exocytosis (GO:2000300)3.90004983
10cell communication by electrical coupling involved in cardiac conduction (GO:0086064)3.88072077
11regulation of respiratory gaseous exchange by neurological system process (GO:0002087)3.87532496
12regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor act3.82472602
13glutamate secretion (GO:0014047)3.80286188
14vocalization behavior (GO:0071625)3.69057751
15regulation of glutamate receptor signaling pathway (GO:1900449)3.59975300
16protein localization to synapse (GO:0035418)3.57159654
17positive regulation of dendritic spine morphogenesis (GO:0061003)3.55216641
18cell communication by electrical coupling (GO:0010644)3.52261111
19gamma-aminobutyric acid transport (GO:0015812)3.48082866
20positive regulation of dendritic spine development (GO:0060999)3.48078191
21postsynaptic membrane organization (GO:0001941)3.46570226
22cellular potassium ion homeostasis (GO:0030007)3.46337881
23positive regulation of potassium ion transmembrane transporter activity (GO:1901018)3.44970838
24regulation of synaptic vesicle transport (GO:1902803)3.43872028
25pyrimidine nucleobase catabolic process (GO:0006208)3.41287851
26neurotransmitter secretion (GO:0007269)3.40341333
27ionotropic glutamate receptor signaling pathway (GO:0035235)3.36701272
28response to pheromone (GO:0019236)3.34169152
29neuron cell-cell adhesion (GO:0007158)3.33850913
30sodium ion export (GO:0071436)3.33501614
31regulation of neuronal synaptic plasticity (GO:0048168)3.30914711
32regulation of synapse structural plasticity (GO:0051823)3.26426223
33layer formation in cerebral cortex (GO:0021819)3.23585130
34exploration behavior (GO:0035640)3.23412947
35neuromuscular process controlling balance (GO:0050885)3.22386030
36regulation of N-methyl-D-aspartate selective glutamate receptor activity (GO:2000310)3.22228390
37membrane depolarization during cardiac muscle cell action potential (GO:0086012)3.21045807
38neurotransmitter-gated ion channel clustering (GO:0072578)3.16526795
39regulation of respiratory system process (GO:0044065)3.16485799
40regulation of cAMP-dependent protein kinase activity (GO:2000479)3.16142026
41establishment of mitochondrion localization, microtubule-mediated (GO:0034643)3.15467727
42mitochondrion transport along microtubule (GO:0047497)3.15467727
43regulation of long-term neuronal synaptic plasticity (GO:0048169)3.14663895
44positive regulation of synaptic transmission, GABAergic (GO:0032230)3.14545830
45positive regulation of synaptic transmission, dopaminergic (GO:0032226)3.14246748
46synaptic vesicle endocytosis (GO:0048488)3.09021346
47activation of protein kinase A activity (GO:0034199)3.05284520
48mating behavior (GO:0007617)3.04610076
49presynaptic membrane assembly (GO:0097105)3.04068701
50synaptic vesicle docking involved in exocytosis (GO:0016081)3.00942225
51regulation of acetyl-CoA biosynthetic process from pyruvate (GO:0010510)2.98015592
52DNA double-strand break processing (GO:0000729)2.96892424
53regulation of excitatory postsynaptic membrane potential (GO:0060079)2.95522213
54cell migration in hindbrain (GO:0021535)2.95513793
55establishment of mitochondrion localization (GO:0051654)2.94410335
56nucleobase catabolic process (GO:0046113)2.93017062
57glutamate receptor signaling pathway (GO:0007215)2.92430696
58negative regulation of DNA recombination (GO:0045910)2.90405195
59proline biosynthetic process (GO:0006561)2.90149683
60positive regulation of potassium ion transmembrane transport (GO:1901381)2.90053180
61proline transport (GO:0015824)2.88845698
62dendrite morphogenesis (GO:0048813)2.87861740
63regulation of cofactor metabolic process (GO:0051193)2.87817725
64regulation of coenzyme metabolic process (GO:0051196)2.87817725
65cell communication involved in cardiac conduction (GO:0086065)2.86872136
66neurotransmitter transport (GO:0006836)2.86288447
67synaptic transmission, glutamatergic (GO:0035249)2.85588807
68intraciliary transport (GO:0042073)2.84471851
69regulation of cardiac muscle contraction by calcium ion signaling (GO:0010882)2.84140361
70regulation of postsynaptic membrane potential (GO:0060078)2.83466194
71positive regulation of membrane potential (GO:0045838)2.83458366
72regulation of dendritic spine morphogenesis (GO:0061001)2.83427493
73establishment of integrated proviral latency (GO:0075713)2.83379653
74glycine transport (GO:0015816)2.82687062
75neuromuscular process (GO:0050905)2.79762284
76long-term memory (GO:0007616)2.79163789
77regulation of acyl-CoA biosynthetic process (GO:0050812)2.79042506
78ribonucleoprotein complex disassembly (GO:0032988)2.78969254
79neuron-neuron synaptic transmission (GO:0007270)2.74886556
80regulation of atrial cardiac muscle cell membrane depolarization (GO:0060371)2.73800990
81membrane depolarization during action potential (GO:0086010)2.71484689
82regulation of ryanodine-sensitive calcium-release channel activity (GO:0060314)2.71345882
83potassium ion import (GO:0010107)2.70542843
84regulation of respiratory gaseous exchange (GO:0043576)2.70376500
85presynaptic membrane organization (GO:0097090)2.68342810
86dendritic spine morphogenesis (GO:0060997)2.67704417
87negative regulation of amyloid precursor protein catabolic process (GO:1902992)2.66919232
88regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion (GO2.65330859
89cerebellar Purkinje cell differentiation (GO:0021702)2.60266804
90regulation of neurotransmitter levels (GO:0001505)2.60082657
91regulation of dendritic spine development (GO:0060998)2.59704405
92cullin deneddylation (GO:0010388)2.57684298
93regulation of inhibitory postsynaptic membrane potential (GO:0060080)2.56841171
94cellular sodium ion homeostasis (GO:0006883)2.56815353
95regulation of sulfur metabolic process (GO:0042762)2.56631975
96proline metabolic process (GO:0006560)2.56380677
97positive regulation of synaptic transmission, glutamatergic (GO:0051968)2.55967072
98axonal fasciculation (GO:0007413)2.54969606
99positive regulation of mitochondrial fission (GO:0090141)2.53392138
100membrane depolarization (GO:0051899)2.53362342
101organelle transport along microtubule (GO:0072384)2.52770263
102neuronal ion channel clustering (GO:0045161)2.52566973
103DNA ligation (GO:0006266)2.52269326
104positive regulation of ryanodine-sensitive calcium-release channel activity (GO:0060316)2.52030711
105negative regulation of heart rate (GO:0010459)2.51229181
106C4-dicarboxylate transport (GO:0015740)2.49307369
107regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum (GO:0010880)2.49159415
108glycogen catabolic process (GO:0005980)2.48772577
109calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules (GO:0016339)2.47734189
110positive regulation of potassium ion transport (GO:0043268)2.47567699
111transmission of nerve impulse (GO:0019226)2.46983432
112regulation of synaptic plasticity (GO:0048167)2.46464756
113neuron recognition (GO:0008038)2.45977313
114organelle disassembly (GO:1903008)2.45683483
115membrane hyperpolarization (GO:0060081)2.44927592
116mitochondrial outer membrane permeabilization involved in programmed cell death (GO:1902686)2.43610480
117positive regulation of mitochondrial membrane permeability involved in apoptotic process (GO:19021102.43610480
118membrane repolarization (GO:0086009)2.43583723
119detection of calcium ion (GO:0005513)2.41223777
120central nervous system projection neuron axonogenesis (GO:0021952)2.40852185
121positive regulation of synapse maturation (GO:0090129)2.39421801
122double-strand break repair via nonhomologous end joining (GO:0006303)2.38534127
123non-recombinational repair (GO:0000726)2.38534127
124regulation of sarcomere organization (GO:0060297)2.38203489
125microtubule depolymerization (GO:0007019)2.37334733
126branched-chain amino acid catabolic process (GO:0009083)2.35809218
127CENP-A containing nucleosome assembly (GO:0034080)2.34847634
128DNA damage response, detection of DNA damage (GO:0042769)2.34343386
129chromatin remodeling at centromere (GO:0031055)2.33217877
130mitotic sister chromatid cohesion (GO:0007064)2.32292250
131nonmotile primary cilium assembly (GO:0035058)2.28892975
132cholesterol biosynthetic process (GO:0006695)2.25359129
133protein deneddylation (GO:0000338)2.23567689
134nuclear pore organization (GO:0006999)2.16663589
135peptidyl-cysteine modification (GO:0018198)2.16177565
136regulation of growth hormone secretion (GO:0060123)2.15324705
137L-serine metabolic process (GO:0006563)2.12687714
138establishment of viral latency (GO:0019043)2.11304326
139apical protein localization (GO:0045176)2.10498511
140microtubule anchoring (GO:0034453)2.09795181
141negative regulation of mitotic sister chromatid separation (GO:2000816)2.08825851
142negative regulation of sister chromatid segregation (GO:0033046)2.08825851
143negative regulation of mitotic metaphase/anaphase transition (GO:0045841)2.08825851
144negative regulation of metaphase/anaphase transition of cell cycle (GO:1902100)2.08825851
145negative regulation of mitotic sister chromatid segregation (GO:0033048)2.08825851
146synapse assembly (GO:0007416)2.08552467
147mitotic spindle organization (GO:0007052)2.08418826
148microtubule-based transport (GO:0010970)2.08255938
149cytoskeleton-dependent intracellular transport (GO:0030705)2.07290416
150neural tube formation (GO:0001841)2.07113094
151mitotic spindle checkpoint (GO:0071174)2.06076937
152histone exchange (GO:0043486)2.05718608
153regulation of cell communication by electrical coupling (GO:0010649)2.05107644
154spermatid nucleus differentiation (GO:0007289)2.04928783
155paraxial mesoderm development (GO:0048339)2.04398829
156sterol biosynthetic process (GO:0016126)2.04376571
157spindle checkpoint (GO:0031577)2.04165106
158histone H2A acetylation (GO:0043968)2.03883665
159membrane budding (GO:0006900)2.03679477
160hippocampus development (GO:0021766)2.03277062
161regulation of attachment of spindle microtubules to kinetochore (GO:0051988)2.03233309
162DNA replication-independent nucleosome organization (GO:0034724)2.01656039
163DNA replication-independent nucleosome assembly (GO:0006336)2.01656039
164ribosome assembly (GO:0042255)2.01436758
165mitotic spindle assembly checkpoint (GO:0007094)2.00979399
166cerebral cortex radially oriented cell migration (GO:0021799)2.00199594
167nuclear pore complex assembly (GO:0051292)1.99515087
168regulation of helicase activity (GO:0051095)1.99291170
169microtubule polymerization or depolymerization (GO:0031109)1.98653835
170cilium assembly (GO:0042384)1.97993967
171asymmetric protein localization (GO:0008105)1.97982226
172olfactory bulb development (GO:0021772)1.97282839
173spindle assembly checkpoint (GO:0071173)1.97196263
174negative regulation of chromosome segregation (GO:0051985)1.97005825
175regulation of mitotic metaphase/anaphase transition (GO:0030071)1.96102685
176regulation of metaphase/anaphase transition of cell cycle (GO:1902099)1.96102685
177RNA-dependent DNA replication (GO:0006278)1.95034224
178postreplication repair (GO:0006301)1.94905502
179regulation of mitotic sister chromatid separation (GO:0010965)1.94414120
180regulation of mitotic sister chromatid segregation (GO:0033047)1.94414120
181regulation of sister chromatid segregation (GO:0033045)1.94414120

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1EZH2_22144423_ChIP-Seq_EOC_Human5.74420097
2SALL1_21062744_ChIP-ChIP_HESCs_Human3.16648077
3* POU3F2_20337985_ChIP-ChIP_501MEL_Human3.01991023
4GBX2_23144817_ChIP-Seq_PC3_Human2.74910966
5JARID2_20064375_ChIP-Seq_MESCs_Mouse2.74688965
6SUZ12_18692474_ChIP-Seq_MESCs_Mouse2.72129456
7RBPJ_22232070_ChIP-Seq_NCS_Mouse2.68844682
8SUZ12_18555785_ChIP-Seq_MESCs_Mouse2.65212824
9EZH2_18974828_ChIP-Seq_MESCs_Mouse2.52380984
10RNF2_18974828_ChIP-Seq_MESCs_Mouse2.52380984
11JARID2_20075857_ChIP-Seq_MESCs_Mouse2.52255182
12ZFP57_27257070_Chip-Seq_ESCs_Mouse2.42447079
13FUS_26573619_Chip-Seq_HEK293_Human2.40641549
14REST_21632747_ChIP-Seq_MESCs_Mouse2.32939438
15MTF2_20144788_ChIP-Seq_MESCs_Mouse2.31528387
16SUZ12_18692474_ChIP-Seq_MEFs_Mouse2.30975012
17EZH2_27304074_Chip-Seq_ESCs_Mouse2.26797059
18EWS_26573619_Chip-Seq_HEK293_Human2.23141945
19CEBPD_23245923_ChIP-Seq_MEFs_Mouse2.22500425
20SUZ12_20075857_ChIP-Seq_MESCs_Mouse2.21973858
21ERG_21242973_ChIP-ChIP_JURKAT_Human2.19876850
22SUZ12_18974828_ChIP-Seq_MESCs_Mouse2.17353573
23SUZ12_16625203_ChIP-ChIP_MESCs_Mouse2.16164154
24SUZ12_27294783_Chip-Seq_ESCs_Mouse2.15959757
25RARB_27405468_Chip-Seq_BRAIN_Mouse2.07563418
26EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse2.06694241
27DROSHA_22980978_ChIP-Seq_HELA_Human2.05067042
28KDM5B_21448134_ChIP-Seq_MESCs_Mouse2.02753559
29REST_18959480_ChIP-ChIP_MESCs_Mouse2.02302070
30EZH2_27294783_Chip-Seq_ESCs_Mouse2.00686826
31EED_16625203_ChIP-ChIP_MESCs_Mouse1.99193280
32RNF2_27304074_Chip-Seq_ESCs_Mouse1.91605018
33* SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.91204614
34FLI1_27457419_Chip-Seq_LIVER_Mouse1.78891826
35OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.77579312
36HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse1.76123546
37AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human1.76080261
38ELK1_19687146_ChIP-ChIP_HELA_Human1.74449444
39ESRRB_18555785_ChIP-Seq_MESCs_Mouse1.74449023
40VDR_22108803_ChIP-Seq_LS180_Human1.73455305
41PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse1.69744376
42CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons1.61388365
43* KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human1.60961258
44MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse1.60778926
45MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human1.57213824
46HOXD13_18407260_ChIP-ChIP_DEVELOPING-LIMBS_Mouse1.53366841
47WT1_19549856_ChIP-ChIP_CCG9911_Human1.52420852
48RCOR1_19997604_ChIP-ChIP_NEURONS_Mouse1.52305584
49NR4A2_19515692_ChIP-ChIP_MN9D_Mouse1.52167913
50PCGF2_27294783_Chip-Seq_ESCs_Mouse1.51708568
51E2F4_17652178_ChIP-ChIP_JURKAT_Human1.50081525
52PRDM5_23873026_ChIP-Seq_MEFs_Mouse1.48582902
53AR_21909140_ChIP-Seq_LNCAP_Human1.47825082
54PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse1.46055388
55ZFP322A_24550733_ChIP-Seq_MESCs_Mouse1.45240926
56IKZF1_21737484_ChIP-ChIP_HCT116_Human1.43841579
57AR_21572438_ChIP-Seq_LNCaP_Human1.42502723
58RCOR3_21632747_ChIP-Seq_MESCs_Mouse1.42074557
59TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse1.40886710
60POU5F1_16153702_ChIP-ChIP_HESCs_Human1.40152251
61TOP2B_26459242_ChIP-Seq_MCF-7_Human1.39699076
62ZNF274_21170338_ChIP-Seq_K562_Hela1.37456767
63RING1B_27294783_Chip-Seq_ESCs_Mouse1.37086306
64PADI4_21655091_ChIP-ChIP_MCF-7_Human1.36673158
65CDX2_19796622_ChIP-Seq_MESCs_Mouse1.35878687
66KDM2B_26808549_Chip-Seq_K562_Human1.35215441
67MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.34960412
68RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.33934905
69NANOG_18555785_Chip-Seq_ESCs_Mouse1.33780102
70RING1B_27294783_Chip-Seq_NPCs_Mouse1.31919434
71E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse1.31857558
72SMAD3_22036565_ChIP-Seq_ESCs_Mouse1.30997601
73PHC1_16625203_ChIP-ChIP_MESCs_Mouse1.30778705
74SUZ12_27294783_Chip-Seq_NPCs_Mouse1.28816567
75TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.28420161
76* TEAD4_22529382_ChIP-Seq_TROPHECTODERM_Mouse1.28020076
77UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human1.27357399
78RNF2_27304074_Chip-Seq_NSC_Mouse1.25911881
79GABP_17652178_ChIP-ChIP_JURKAT_Human1.25437022
80EZH2_27294783_Chip-Seq_NPCs_Mouse1.24760168
81CTCF_27219007_Chip-Seq_Bcells_Human1.24088112
82HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human1.23281366
83E2F7_22180533_ChIP-Seq_HELA_Human1.22494742
84LXR_22292898_ChIP-Seq_THP-1_Human1.22411747
85RCOR2_21632747_ChIP-Seq_MESCs_Mouse1.22325099
86RNF2_16625203_ChIP-ChIP_MESCs_Mouse1.20871643
87DNAJC2_21179169_ChIP-ChIP_NT2_Human1.20331278
88FOXP2_21765815_ChIP-ChIP_NEURO2A_Mouse1.19499769
89EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse1.18990151
90ESR1_15608294_ChIP-ChIP_MCF-7_Human1.18570372
91PCGF2_27294783_Chip-Seq_NPCs_Mouse1.18046278
92CTBP1_25329375_ChIP-Seq_LNCAP_Human1.17924174
93KLF5_20875108_ChIP-Seq_MESCs_Mouse1.17547875
94SOX9_26525672_Chip-Seq_HEART_Mouse1.17158754
95ZFP281_18757296_ChIP-ChIP_E14_Mouse1.16383426
96ESR1_20079471_ChIP-ChIP_T-47D_Human1.15349143
97ER_23166858_ChIP-Seq_MCF-7_Human1.15038485
98SMAD4_21799915_ChIP-Seq_A2780_Human1.14595911
99TP53_20018659_ChIP-ChIP_R1E_Mouse1.14334495
100WT1_25993318_ChIP-Seq_PODOCYTE_Human1.13813603
101YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.13117822
102CBP_20019798_ChIP-Seq_JUKART_Human1.12410928
103IRF4_20064451_ChIP-Seq_CD4+T_Mouse1.12410928
104P53_22387025_ChIP-Seq_ESCs_Mouse1.11776426
105ZFP281_18358816_ChIP-ChIP_MESCs_Mouse1.11227976
106MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human1.11216003
107TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.10815421
108* CREB1_15753290_ChIP-ChIP_HEK293T_Human1.10587730
109SOX2_16153702_ChIP-ChIP_HESCs_Human1.10564744
110E2F1_18555785_Chip-Seq_ESCs_Mouse1.10412602
111EGR1_20690147_ChIP-Seq_ERYTHROLEUKEMIA_Human1.10410879
112PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.08370041
113NR3C1_21868756_ChIP-Seq_MCF10A_Human1.07416845
114GLI1_17442700_ChIP-ChIP_MESCs_Mouse1.06293447
115NFE2_27457419_Chip-Seq_LIVER_Mouse1.06290410
116TBX3_20139965_ChIP-Seq_ESCs_Mouse1.06194135
117TBX3_20139965_ChIP-Seq_MESCs_Mouse1.06007020
118NANOG_18700969_ChIP-ChIP_MESCs_Mouse1.05881983
119JUN_21703547_ChIP-Seq_K562_Human1.05645329
120FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse1.05387812
121BMI1_23680149_ChIP-Seq_NPCS_Mouse1.05096379
122CMYC_18555785_Chip-Seq_ESCs_Mouse1.04643305
123NFE2L2_20460467_ChIP-Seq_MEFs_Mouse1.03452902
124NRF2_20460467_ChIP-Seq_MEFs_Mouse1.03452902
125THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse1.03343978
126AR_19668381_ChIP-Seq_PC3_Human1.03258706
127SUZ12_18555785_Chip-Seq_ESCs_Mouse1.02369444
128RUNX2_22187159_ChIP-Seq_PCA_Human1.01947502
129TAL1_26923725_Chip-Seq_HPCs_Mouse1.01337504
130KLF4_25985364_ChIP-Seq_ATHEROSCLEROSIS_LESION_Mouse1.00907279
131TFAP2C_20629094_ChIP-Seq_MCF-7_Human1.00862698
132KDM2B_26808549_Chip-Seq_SUP-B15_Human1.00264152
133FOXM1_26456572_ChIP-Seq_MCF-7_Human0.99557704
134MYC_18940864_ChIP-ChIP_HL60_Human0.99157138
135SALL4_18804426_ChIP-ChIP_MESCs_Mouse0.98815088
136NANOG_16153702_ChIP-ChIP_HESCs_Human0.98292555
137* SOX2_21211035_ChIP-Seq_LN229_Gbm0.98285711
138P300_18555785_Chip-Seq_ESCs_Mouse0.98027409
139WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse0.97767985
140STAT3_24763339_ChIP-Seq_IMN-ESCs_Mouse0.97629095
141SMARCD1_25818293_ChIP-Seq_ESCs_Mouse0.97467609
142CTNNB1_24651522_ChIP-Seq_LGR5+_INTESTINAL_STEM_Human0.97368746
143NR3C1_23031785_ChIP-Seq_PC12_Mouse0.96205930
144SMAD3_21741376_ChIP-Seq_HESCs_Human0.95385465
145ZFP281_27345836_Chip-Seq_ESCs_Mouse0.94775206
146STAT3_23295773_ChIP-Seq_U87_Human0.94519032
147TET1_21490601_ChIP-Seq_MESCs_Mouse0.93740129
148CTBP2_25329375_ChIP-Seq_LNCAP_Human0.92747182
149CREB1_26743006_Chip-Seq_LNCaP-abl_Human0.92498750
150OLIG2_26023283_ChIP-Seq_AINV15_Mouse0.88617445
151* TCF3_18467660_ChIP-ChIP_MESCs_Mouse0.88361026
152CBX2_27304074_Chip-Seq_ESCs_Mouse0.87623147
153PIAS1_25552417_ChIP-Seq_VCAP_Human0.86892744
154MEIS1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse0.86825027
155SMAD4_21741376_ChIP-Seq_HESCs_Human0.86818178
156CTNNB1_20460455_ChIP-Seq_HCT116_Human0.86601741
157* NR1I2_20693526_ChIP-Seq_LIVER_Mouse0.85880585
158IGF1R_20145208_ChIP-Seq_DFB_Human0.84947832
159GATA2_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.84766218
160TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human0.84634126
161AR_25329375_ChIP-Seq_VCAP_Human0.84384011
162YAP1_20516196_ChIP-Seq_MESCs_Mouse0.83485284
163* SOX9_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse0.82949015
164SMAD3_21741376_ChIP-Seq_EPCs_Human0.82556761
165RXR_22158963_ChIP-Seq_LIVER_Mouse0.82370750
166ESR2_21235772_ChIP-Seq_MCF-7_Human0.82360170
167BACH1_22875853_ChIP-PCR_HELA_AND_SCP4_Human0.81810066
168SMAD2/3_21741376_ChIP-Seq_EPCs_Human0.81786005
169KDM2B_26808549_Chip-Seq_JURKAT_Human0.81543770
170TAF15_26573619_Chip-Seq_HEK293_Human0.79743521
171BCAT_22108803_ChIP-Seq_LS180_Human0.78866402
172TCF4_23295773_ChIP-Seq_U87_Human0.77499422
173MYCN_27167114_Chip-Seq_NEUROBLASTOMA_Human0.76145470
174GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.76023069
175P53_22127205_ChIP-Seq_FIBROBLAST_Human0.75916806
176* P300_19829295_ChIP-Seq_ESCs_Human0.74292836

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0004859_abnormal_synaptic_plasticity5.28461039
2MP0003880_abnormal_central_pattern4.16825106
3MP0003635_abnormal_synaptic_transmissio3.40057803
4MP0004270_analgesia2.75334047
5MP0009046_muscle_twitch2.68331250
6MP0002064_seizures2.60308879
7MP0009745_abnormal_behavioral_response2.57498968
8MP0001968_abnormal_touch/_nociception2.57489133
9MP0002063_abnormal_learning/memory/cond2.57369690
10MP0001529_abnormal_vocalization2.33656652
11MP0000751_myopathy2.30351761
12MP0002572_abnormal_emotion/affect_behav2.26517845
13MP0002272_abnormal_nervous_system2.24346327
14MP0002733_abnormal_thermal_nociception2.12309347
15MP0002822_catalepsy2.09905798
16MP0005171_absent_coat_pigmentation1.94934102
17MP0002067_abnormal_sensory_capabilities1.93480507
18MP0001970_abnormal_pain_threshold1.92820356
19MP0001486_abnormal_startle_reflex1.90970362
20MP0002735_abnormal_chemical_nociception1.88679440
21MP0003121_genomic_imprinting1.87145085
22MP0002734_abnormal_mechanical_nocicepti1.86414797
23MP0004233_abnormal_muscle_weight1.82364258
24MP0002909_abnormal_adrenal_gland1.81799232
25MP0002736_abnormal_nociception_after1.79341863
26MP0003890_abnormal_embryonic-extraembry1.78742558
27MP0003122_maternal_imprinting1.76725393
28MP0003646_muscle_fatigue1.74094275
29MP0006276_abnormal_autonomic_nervous1.72672717
30MP0003941_abnormal_skin_development1.70707499
31MP0003787_abnormal_imprinting1.69632911
32MP0005248_abnormal_Harderian_gland1.68599959
33MP0002102_abnormal_ear_morphology1.68210047
34MP0004145_abnormal_muscle_electrophysio1.67965168
35MP0000569_abnormal_digit_pigmentation1.66535276
36MP0008569_lethality_at_weaning1.65567604
37MP0001440_abnormal_grooming_behavior1.62996468
38MP0001501_abnormal_sleep_pattern1.59807056
39MP0005423_abnormal_somatic_nervous1.59623958
40MP0001299_abnormal_eye_distance/1.59352117
41MP0005187_abnormal_penis_morphology1.56478230
42MP0004130_abnormal_muscle_cell1.55704520
43MP0000955_abnormal_spinal_cord1.55127348
44MP0004924_abnormal_behavior1.55086544
45MP0005386_behavior/neurological_phenoty1.55086544
46MP0004142_abnormal_muscle_tone1.54593137
47MP0003937_abnormal_limbs/digits/tail_de1.54203220
48MP0003283_abnormal_digestive_organ1.54168109
49MP0003567_abnormal_fetal_cardiomyocyte1.53021923
50MP0002184_abnormal_innervation1.48835878
51MP0002837_dystrophic_cardiac_calcinosis1.46299554
52MP0005085_abnormal_gallbladder_physiolo1.44939989
53MP0003137_abnormal_impulse_conducting1.41760596
54MP0004811_abnormal_neuron_physiology1.40109195
55MP0008877_abnormal_DNA_methylation1.40096539
56MP0010234_abnormal_vibrissa_follicle1.38661124
57MP0003633_abnormal_nervous_system1.36811654
58MP0000778_abnormal_nervous_system1.36734930
59MP0004043_abnormal_pH_regulation1.36007032
60MP0002233_abnormal_nose_morphology1.35920744
61MP0006072_abnormal_retinal_apoptosis1.33713725
62MP0001177_atelectasis1.33165294
63MP0003329_amyloid_beta_deposits1.30414253
64MP0002066_abnormal_motor_capabilities/c1.30398073
65MP0002557_abnormal_social/conspecific_i1.29552588
66MP0005499_abnormal_olfactory_system1.28330887
67MP0005394_taste/olfaction_phenotype1.28330887
68MP0004885_abnormal_endolymph1.27863195
69MP0008058_abnormal_DNA_repair1.26994938
70MP0004215_abnormal_myocardial_fiber1.26542093
71MP0009780_abnormal_chondrocyte_physiolo1.25849052
72MP0002882_abnormal_neuron_morphology1.25819679
73MP0005551_abnormal_eye_electrophysiolog1.25438625
74MP0003221_abnormal_cardiomyocyte_apopto1.23449629
75MP0009697_abnormal_copulation1.23049438
76MP0008789_abnormal_olfactory_epithelium1.22205139
77MP0004147_increased_porphyrin_level1.21976364
78MP0001502_abnormal_circadian_rhythm1.21099136
79MP0003123_paternal_imprinting1.20152767
80MP0002090_abnormal_vision1.19828875
81MP0002938_white_spotting1.19495314
82MP0000647_abnormal_sebaceous_gland1.18530889
83MP0005645_abnormal_hypothalamus_physiol1.17303990
84MP0002751_abnormal_autonomic_nervous1.16434644
85MP0004957_abnormal_blastocyst_morpholog1.12970664
86MP0001293_anophthalmia1.11548041
87MP0008932_abnormal_embryonic_tissue1.11457587
88MP0004858_abnormal_nervous_system1.09980828
89MP0010094_abnormal_chromosome_stability1.09972043
90MP0004084_abnormal_cardiac_muscle1.08444111
91MP0005535_abnormal_body_temperature1.07967345
92MP0003385_abnormal_body_wall1.07137257
93MP0002229_neurodegeneration1.06396713
94MP0000747_muscle_weakness1.05211970
95MP0003879_abnormal_hair_cell1.05129186
96MP0002697_abnormal_eye_size1.04958258
97MP0002139_abnormal_hepatobiliary_system1.04718872
98MP0008961_abnormal_basal_metabolism1.02481791
99MP0005623_abnormal_meninges_morphology1.02254789
100MP0005365_abnormal_bile_salt1.01816619
101MP0002084_abnormal_developmental_patter1.01257029
102MP0003755_abnormal_palate_morphology1.01209755
103MP0002234_abnormal_pharynx_morphology0.98747246
104MP0005646_abnormal_pituitary_gland0.97748643
105MP0009703_decreased_birth_body0.96985026
106MP0003861_abnormal_nervous_system0.95675083
107MP0003631_nervous_system_phenotype0.94560482
108MP0009672_abnormal_birth_weight0.93256412
109MP0003119_abnormal_digestive_system0.93227462
110MP0005253_abnormal_eye_physiology0.92997169
111MP0005083_abnormal_biliary_tract0.92187973
112MP0008874_decreased_physiological_sensi0.92099609
113MP0001188_hyperpigmentation0.91865759
114MP0005330_cardiomyopathy0.91255309
115MP0000537_abnormal_urethra_morphology0.91250502
116MP0008057_abnormal_DNA_replication0.89127912
117MP0004133_heterotaxia0.88103191
118MP0003718_maternal_effect0.87950733
119MP0000516_abnormal_urinary_system0.87148161
120MP0005367_renal/urinary_system_phenotyp0.87148161
121MP0005174_abnormal_tail_pigmentation0.87146874
122MP0002876_abnormal_thyroid_physiology0.85841940
123MP0002152_abnormal_brain_morphology0.85242267
124MP0003111_abnormal_nucleus_morphology0.84884479
125MP0002269_muscular_atrophy0.84331194
126MP0002638_abnormal_pupillary_reflex0.83754470
127MP0008775_abnormal_heart_ventricle0.83200264
128MP0000631_abnormal_neuroendocrine_gland0.82327034
129MP0001286_abnormal_eye_development0.82132065
130MP0003634_abnormal_glial_cell0.82021543
131MP0004484_altered_response_of0.81939854
132MP0004085_abnormal_heartbeat0.81193084
133MP0003075_altered_response_to0.80185179
134MP0000015_abnormal_ear_pigmentation0.79990824
135MP0004197_abnormal_fetal_growth/weight/0.79504998
136MP0006054_spinal_hemorrhage0.79225118
137MP0006035_abnormal_mitochondrial_morpho0.79051021
138MP0009379_abnormal_foot_pigmentation0.77930159
139MP0003172_abnormal_lysosome_physiology0.76445942
140MP0005360_urolithiasis0.76156465
141MP0001984_abnormal_olfaction0.75924902
142MP0000749_muscle_degeneration0.75923840
143MP0002752_abnormal_somatic_nervous0.74898578
144MP0002009_preneoplasia0.73730415
145MP0000639_abnormal_adrenal_gland0.72933462
146MP0004036_abnormal_muscle_relaxation0.71674182
147MP0005332_abnormal_amino_acid0.71156724
148MP0000579_abnormal_nail_morphology0.69772562
149MP0003045_fibrosis0.69120267
150MP0002069_abnormal_eating/drinking_beha0.69052710
151MP0002078_abnormal_glucose_homeostasis0.69038918
152MP0000013_abnormal_adipose_tissue0.68897469
153MP0002249_abnormal_larynx_morphology0.66853736
154MP0005620_abnormal_muscle_contractility0.66847601
155MP0003656_abnormal_erythrocyte_physiolo0.66232063

Predicted human phenotypes

RankGene SetZ-score
1Focal motor seizures (HP:0011153)5.85047715
2Myokymia (HP:0002411)5.47279807
3Action tremor (HP:0002345)4.29260539
4Visual hallucinations (HP:0002367)4.23429266
5Focal seizures (HP:0007359)4.07012017
6Febrile seizures (HP:0002373)3.68602474
7Atonic seizures (HP:0010819)3.60034458
8Dysdiadochokinesis (HP:0002075)3.41981402
9Cortical dysplasia (HP:0002539)3.40017704
10Progressive cerebellar ataxia (HP:0002073)3.23017827
11Annular pancreas (HP:0001734)3.20224344
12Absence seizures (HP:0002121)3.20108218
13Papillary thyroid carcinoma (HP:0002895)3.15858997
14Epileptic encephalopathy (HP:0200134)3.00335957
15Gait imbalance (HP:0002141)3.00121994
16Dialeptic seizures (HP:0011146)2.99615554
17Exercise-induced myalgia (HP:0003738)2.99136278
18Depression (HP:0000716)2.96617092
19Gaze-evoked nystagmus (HP:0000640)2.95450811
20Congenital primary aphakia (HP:0007707)2.89937733
21Exercise-induced muscle cramps (HP:0003710)2.83949223
22Nephrogenic diabetes insipidus (HP:0009806)2.77695318
23Turricephaly (HP:0000262)2.76169755
24Volvulus (HP:0002580)2.75746443
25Medial flaring of the eyebrow (HP:0010747)2.72230387
26Generalized tonic-clonic seizures (HP:0002069)2.72190179
27Ketoacidosis (HP:0001993)2.71697389
28Scanning speech (HP:0002168)2.69614381
29Dysmetria (HP:0001310)2.68062476
30Status epilepticus (HP:0002133)2.65613798
31Genital tract atresia (HP:0001827)2.61863601
32Decreased number of large peripheral myelinated nerve fibers (HP:0003387)2.58713563
33Hypercortisolism (HP:0001578)2.58335585
34Anxiety (HP:0000739)2.57973776
35Vaginal atresia (HP:0000148)2.56305658
36Pheochromocytoma (HP:0002666)2.51973464
37Thyroid carcinoma (HP:0002890)2.50401146
38Broad-based gait (HP:0002136)2.49596016
39Intestinal atresia (HP:0011100)2.48863544
40Obstructive sleep apnea (HP:0002870)2.45138851
41Sudden death (HP:0001699)2.43036919
42Ventricular fibrillation (HP:0001663)2.41256353
43Ankle clonus (HP:0011448)2.39197187
44Intention tremor (HP:0002080)2.37782332
45Supranuclear gaze palsy (HP:0000605)2.37492270
46Postural instability (HP:0002172)2.31168103
47Abnormality of the lower motor neuron (HP:0002366)2.31029076
48Abnormal EKG (HP:0003115)2.29696108
49Truncal ataxia (HP:0002078)2.27886679
50Medulloblastoma (HP:0002885)2.24582217
51Poor eye contact (HP:0000817)2.22578707
52Amyotrophic lateral sclerosis (HP:0007354)2.22410208
53Increased circulating renin level (HP:0000848)2.21832075
54Colon cancer (HP:0003003)2.21224484
55Fetal akinesia sequence (HP:0001989)2.20767066
56Abnormal social behavior (HP:0012433)2.20093678
57Impaired social interactions (HP:0000735)2.20093678
58Hyperventilation (HP:0002883)2.17462437
59Shoulder girdle muscle weakness (HP:0003547)2.16822539
60Myoglobinuria (HP:0002913)2.15340513
61Ketosis (HP:0001946)2.15249902
62Progressive inability to walk (HP:0002505)2.15036427
63Increased serum pyruvate (HP:0003542)2.12705970
64Clumsiness (HP:0002312)2.12593476
65Dysmetric saccades (HP:0000641)2.11777322
66Poor coordination (HP:0002370)2.10751081
67Hemiparesis (HP:0001269)2.10458054
68Agitation (HP:0000713)2.09913548
69Abnormality of glycolysis (HP:0004366)2.09362424
70Abnormal eating behavior (HP:0100738)2.08054319
71Neuroendocrine neoplasm (HP:0100634)2.07743508
72Growth hormone excess (HP:0000845)2.07493212
73Concave nail (HP:0001598)2.06518996
74Peripheral hypomyelination (HP:0007182)2.06394407
75Lower limb hyperreflexia (HP:0002395)2.06183528
76Broad foot (HP:0001769)2.03740809
77Syncope (HP:0001279)2.02469642
78Prolonged QT interval (HP:0001657)1.98460092
79Hemiplegia (HP:0002301)1.97444284
80Blue irides (HP:0000635)1.97189955
81Abnormality of the labia minora (HP:0012880)1.96355424
82Bradykinesia (HP:0002067)1.96122186
83Cholecystitis (HP:0001082)1.95844165
84Abnormal gallbladder physiology (HP:0012438)1.95844165
85True hermaphroditism (HP:0010459)1.95806438
86Hypothermia (HP:0002045)1.94996394
87Bundle branch block (HP:0011710)1.94986380
88Abnormality of the musculature of the pelvis (HP:0001469)1.93684662
89Abnormality of the hip-girdle musculature (HP:0001445)1.93684662
90Hepatoblastoma (HP:0002884)1.93167830
91Adrenal overactivity (HP:0002717)1.92977644
92Atrophy/Degeneration involving motor neurons (HP:0007373)1.92807444
93Bifid tongue (HP:0010297)1.92737288
94Atrophy/Degeneration involving the corticospinal tracts (HP:0007372)1.92309213
95Degeneration of the lateral corticospinal tracts (HP:0002314)1.92309213
96Renal hypoplasia (HP:0000089)1.92235056
97Limb dystonia (HP:0002451)1.91230057
98Specific learning disability (HP:0001328)1.90851306
99Hypochromic microcytic anemia (HP:0004840)1.90763914
100Elevated circulating parathyroid hormone (PTH) level (HP:0003165)1.88913995
101Abnormality of the astrocytes (HP:0100707)1.88679654
102Astrocytoma (HP:0009592)1.88679654
103Hypoglycemic coma (HP:0001325)1.88144444
104Nuclear cataract (HP:0100018)1.87612590
105Rimmed vacuoles (HP:0003805)1.87190179
106Asymmetric septal hypertrophy (HP:0001670)1.86682005
107Decreased testicular size (HP:0008734)1.86565923
108Primary atrial arrhythmia (HP:0001692)1.86297620
109Postaxial hand polydactyly (HP:0001162)1.86062966
110Impaired vibration sensation in the lower limbs (HP:0002166)1.86051838
111Postural tremor (HP:0002174)1.85387513
112Postnatal microcephaly (HP:0005484)1.85144560
113Micropenis (HP:0000054)1.83969978
114Abnormality of the corticospinal tract (HP:0002492)1.83885897
115Abnormal lung lobation (HP:0002101)1.82389557
116Abnormality of magnesium homeostasis (HP:0004921)1.82267199
117Urinary urgency (HP:0000012)1.82193140
118Diaphragmatic weakness (HP:0009113)1.82134279
119Atrial fibrillation (HP:0005110)1.82009058
120Urinary glycosaminoglycan excretion (HP:0003541)1.81763224
121Mucopolysacchariduria (HP:0008155)1.81763224
122Dysostosis multiplex (HP:0000943)1.80292835
123Glioma (HP:0009733)1.79288385
124Urinary bladder sphincter dysfunction (HP:0002839)1.79269543
125Amblyopia (HP:0000646)1.78643399
126Muscle hypertrophy of the lower extremities (HP:0008968)1.78315862
127Nonprogressive disorder (HP:0003680)1.77450089
128Myotonia (HP:0002486)1.77439704
129Abnormality of pyruvate family amino acid metabolism (HP:0010915)1.76728427
130Abnormality of alanine metabolism (HP:0010916)1.76728427
131Hyperalaninemia (HP:0003348)1.76728427
132Termporal pattern (HP:0011008)1.76156431
133Insidious onset (HP:0003587)1.76156431
134Supraventricular tachycardia (HP:0004755)1.74403250
135Central scotoma (HP:0000603)1.73776900
136Spastic diplegia (HP:0001264)1.73102023
137Mutism (HP:0002300)1.73031189
138Childhood onset (HP:0011463)1.72908953
139Ependymoma (HP:0002888)1.72598325
140Horizontal nystagmus (HP:0000666)1.72544642
141Hyperglycinemia (HP:0002154)1.71933268
142Abnormality of the anterior horn cell (HP:0006802)1.71403641
143Degeneration of anterior horn cells (HP:0002398)1.71403641
144Torticollis (HP:0000473)1.69938234
145Pancreatic fibrosis (HP:0100732)1.69401632
146Split foot (HP:0001839)1.68702489
147Postaxial foot polydactyly (HP:0001830)1.68671169
148Rapidly progressive (HP:0003678)1.68544753
149Abnormality of mucopolysaccharide metabolism (HP:0011020)1.68260702
150Abnormality of polysaccharide metabolism (HP:0011012)1.68260702
151Abnormality of glycosaminoglycan metabolism (HP:0004371)1.68260702
152Excessive salivation (HP:0003781)1.68003492
153Drooling (HP:0002307)1.68003492
154Pelvic girdle muscle weakness (HP:0003749)1.67471568
155Rhabdomyosarcoma (HP:0002859)1.67210137
156Absent eyebrow (HP:0002223)1.66455727
157Hypoglycemic seizures (HP:0002173)1.64351942
158Decreased lacrimation (HP:0000633)1.56902733
159Abnormality of serum amino acid levels (HP:0003112)1.55976309
160Abnormality of serine family amino acid metabolism (HP:0010894)1.55918347
161Abnormality of glycine metabolism (HP:0010895)1.55918347
162Delayed gross motor development (HP:0002194)1.55909869
163Neoplasm of the adrenal gland (HP:0100631)1.55615510
164Nephronophthisis (HP:0000090)1.55099957
165Lissencephaly (HP:0001339)1.54724273
166Neoplasm of the small intestine (HP:0100833)1.54420595
167Renal cortical cysts (HP:0000803)1.52585985
168Biliary tract neoplasm (HP:0100574)1.52504058
169Proximal tubulopathy (HP:0000114)1.51882668
170Hypsarrhythmia (HP:0002521)1.51616286
171Median cleft lip (HP:0000161)1.51187325
172EEG with generalized epileptiform discharges (HP:0011198)1.51076747
173Epileptiform EEG discharges (HP:0011182)1.50761685
174Aplasia/Hypoplasia of the tibia (HP:0005772)1.50412767
175Hyperglycinuria (HP:0003108)1.49683116
176Occipital encephalocele (HP:0002085)1.49505575
177Narrow forehead (HP:0000341)1.48302129
178Pancreatic cysts (HP:0001737)1.47659488
179Aplasia/Hypoplasia of the tongue (HP:0010295)1.47429061
180Short tibia (HP:0005736)1.46784839
181Exotropia (HP:0000577)1.46462777
182Spastic tetraplegia (HP:0002510)1.46212596
183Aplasia/Hypoplasia of the lens (HP:0008063)1.44175687

Predicted kinase interactions (KEA)

RankGene SetZ-score
1TNIK3.63866919
2NTRK33.54456346
3BCR3.23739287
4PINK13.23631249
5MAP3K93.00213731
6ERBB32.73620593
7ICK2.66041161
8EPHA42.56829595
9DDR22.49072412
10TRIM282.43842099
11PHKG22.39232552
12PHKG12.39232552
13MAPK152.28814578
14UHMK12.16027258
15MKNK12.14359356
16NEK12.11491541
17SRPK12.02279761
18MAP3K62.00398554
19MKNK21.99751622
20MAP3K41.97089315
21MAP3K111.88862452
22MAP2K71.87320294
23STK38L1.87174405
24WNK41.85468762
25PLK21.84174766
26TYRO31.75892856
27PBK1.73448985
28MARK11.72661335
29STK381.72323094
30PRKD21.72051143
31PAK61.69358035
32MINK11.69278978
33KSR21.65393885
34FGR1.62338580
35EIF2AK31.60426785
36MAP4K21.56167783
37PLK31.50710557
38DAPK11.48870338
39MAP2K41.48704976
40LMTK21.44659895
41CSNK1A1L1.44024754
42TTK1.41945709
43NTRK11.41130018
44CSNK1G31.41101769
45TSSK61.40086719
46MATK1.37971685
47CAMKK11.37389570
48CSNK1G11.36800028
49DAPK21.32353065
50STK391.31494335
51BUB11.31333024
52NTRK21.26192084
53MUSK1.25358309
54LATS11.23685514
55FRK1.22940768
56PLK41.20789799
57PRKD31.20538094
58LATS21.20111245
59RPS6KA41.12702924
60CDK51.08473584
61CAMKK21.07020794
62BRSK21.06784517
63CDC71.05821582
64CAMK2A1.03842350
65PDGFRA1.03698304
66WNK11.02555005
67CAMK2B0.99199235
68EPHA30.98606693
69PRKCE0.98512308
70AKT30.97904505
71BRD40.97665061
72CDC42BPA0.97560603
73CASK0.89548155
74LIMK10.89226764
75BMX0.88614655
76ZAK0.88569961
77BMPR1B0.88025935
78MAP3K10.86151026
79DYRK20.85847492
80FES0.84761532
81MAP3K120.83291730
82DYRK1B0.82994237
83MAP3K20.81785985
84MAP3K130.81677658
85SCYL20.81248311
86CAMK10.81129658
87OBSCN0.79243796
88PLK10.79224050
89HIPK20.78924454
90EIF2AK10.78316246
91CAMK2D0.77047781
92DYRK30.77025001
93OXSR10.76952344
94CAMK2G0.75713950
95RET0.74226150
96SGK10.73930666
97MAPK130.73819657
98KSR10.73802283
99PNCK0.73179441
100WNK30.72356748
101PRKAA10.72090296
102NUAK10.71644600
103PRPF4B0.71318461
104CCNB10.70783662
105INSRR0.69822148
106STK110.68170012
107TAOK10.68168503
108GRK50.67962767
109STK30.67898309
110WEE10.66923885
111PAK30.65799973
112CDK190.65089855
113BCKDK0.63524571
114SGK4940.63402335
115SGK2230.63402335
116MST40.61583667
117RAF10.59970512
118MAP3K70.59023965
119PRKCG0.57532391
120RIPK40.57445976
121ATM0.56668381
122FGFR10.55694371
123FGFR20.55487093
124FLT30.54583318
125ACVR1B0.54338901
126PRKD10.53749123
127VRK10.52339075
128YES10.52032672
129ERBB40.51692450
130SIK20.51410816
131FER0.50837355
132CSNK1E0.50280272
133BRSK10.49658399
134CDK60.49101755
135CDK150.48976807
136SGK20.48975438
137RIPK10.47985446
138RPS6KA30.47915018
139CDK140.47174626
140SGK30.46847846
141TAF10.46311148
142CSNK1D0.45875969
143CSK0.45491310
144CDK180.45397887
145PKN20.45268258
146TNK20.45198298
147PRKCH0.44433779
148ARAF0.44264634
149CSNK1G20.44225412
150PTK2B0.43781107
151CAMK40.43389016
152CDK11A0.43032730
153TRIB30.42386520
154PRKAA20.42200709
155PRKCZ0.41762407
156MAPK100.40934811
157MARK20.40181277
158DMPK0.39541194

Predicted pathways (KEGG)

RankGene SetZ-score
1Protein export_Homo sapiens_hsa030603.02101476
2Nicotine addiction_Homo sapiens_hsa050332.79088383
3Synaptic vesicle cycle_Homo sapiens_hsa047212.33658471
4GABAergic synapse_Homo sapiens_hsa047272.29117332
5Nitrogen metabolism_Homo sapiens_hsa009102.28631023
6Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049642.27280933
7Terpenoid backbone biosynthesis_Homo sapiens_hsa009002.19009965
8Olfactory transduction_Homo sapiens_hsa047402.08282692
9Fatty acid biosynthesis_Homo sapiens_hsa000612.03088857
10Circadian entrainment_Homo sapiens_hsa047132.02707352
11Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049612.01652786
12Steroid biosynthesis_Homo sapiens_hsa001001.95293100
13Retrograde endocannabinoid signaling_Homo sapiens_hsa047231.89910795
14Glutamatergic synapse_Homo sapiens_hsa047241.88307005
15Non-homologous end-joining_Homo sapiens_hsa034501.87157538
16Morphine addiction_Homo sapiens_hsa050321.83939766
17Insulin secretion_Homo sapiens_hsa049111.81911306
18Long-term potentiation_Homo sapiens_hsa047201.81604175
19Amphetamine addiction_Homo sapiens_hsa050311.78078737
20Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009701.67920348
21Dopaminergic synapse_Homo sapiens_hsa047281.66233857
22Vitamin B6 metabolism_Homo sapiens_hsa007501.64347079
23Salivary secretion_Homo sapiens_hsa049701.59076366
24Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005331.58971290
25Aldosterone synthesis and secretion_Homo sapiens_hsa049251.51173529
26Arginine biosynthesis_Homo sapiens_hsa002201.49511576
27Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042611.49309511
28Cholinergic synapse_Homo sapiens_hsa047251.47969483
29Gastric acid secretion_Homo sapiens_hsa049711.45434748
30Mismatch repair_Homo sapiens_hsa034301.45393596
31Taurine and hypotaurine metabolism_Homo sapiens_hsa004301.42706917
32Basal transcription factors_Homo sapiens_hsa030221.37660725
33Cardiac muscle contraction_Homo sapiens_hsa042601.33019161
34Vasopressin-regulated water reabsorption_Homo sapiens_hsa049621.31337297
35GnRH signaling pathway_Homo sapiens_hsa049121.29510975
36Taste transduction_Homo sapiens_hsa047421.29352283
37Long-term depression_Homo sapiens_hsa047301.29002805
38Cysteine and methionine metabolism_Homo sapiens_hsa002701.28916526
39Oocyte meiosis_Homo sapiens_hsa041141.28493392
40Butanoate metabolism_Homo sapiens_hsa006501.27869104
41Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004001.26969328
42Glycine, serine and threonine metabolism_Homo sapiens_hsa002601.24723753
43Fanconi anemia pathway_Homo sapiens_hsa034601.24454429
442-Oxocarboxylic acid metabolism_Homo sapiens_hsa012101.23403560
45Glycolysis / Gluconeogenesis_Homo sapiens_hsa000101.21304295
46Oxytocin signaling pathway_Homo sapiens_hsa049211.20859355
47RNA transport_Homo sapiens_hsa030131.20001192
48Fatty acid metabolism_Homo sapiens_hsa012121.19948204
49Renin secretion_Homo sapiens_hsa049241.18991564
50Gap junction_Homo sapiens_hsa045401.15323912
51Calcium signaling pathway_Homo sapiens_hsa040201.14625054
52Ubiquitin mediated proteolysis_Homo sapiens_hsa041201.14326655
53Cocaine addiction_Homo sapiens_hsa050301.12166658
54Type II diabetes mellitus_Homo sapiens_hsa049301.09969831
55Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049601.09658218
56Circadian rhythm_Homo sapiens_hsa047101.06849972
57cAMP signaling pathway_Homo sapiens_hsa040241.06397671
58Bile secretion_Homo sapiens_hsa049761.05868802
59Propanoate metabolism_Homo sapiens_hsa006401.03682782
60mRNA surveillance pathway_Homo sapiens_hsa030151.03649646
61Serotonergic synapse_Homo sapiens_hsa047261.03170646
62Cell cycle_Homo sapiens_hsa041101.02478357
63RNA degradation_Homo sapiens_hsa030181.01371210
64Phototransduction_Homo sapiens_hsa047440.99312123
65Spliceosome_Homo sapiens_hsa030400.98831331
66beta-Alanine metabolism_Homo sapiens_hsa004100.97763066
67Hippo signaling pathway_Homo sapiens_hsa043900.97541964
68Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.95924371
69Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047500.95634547
70Melanogenesis_Homo sapiens_hsa049160.93397778
71Citrate cycle (TCA cycle)_Homo sapiens_hsa000200.92743711
72Dorso-ventral axis formation_Homo sapiens_hsa043200.92201648
73Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.91165532
74Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.90495448
75Selenocompound metabolism_Homo sapiens_hsa004500.90307442
76Nucleotide excision repair_Homo sapiens_hsa034200.87580085
77Glucagon signaling pathway_Homo sapiens_hsa049220.87321664
78mTOR signaling pathway_Homo sapiens_hsa041500.86186328
79Longevity regulating pathway - mammal_Homo sapiens_hsa042110.84543470
80Proteasome_Homo sapiens_hsa030500.83929722
81Peroxisome_Homo sapiens_hsa041460.83863012
82Estrogen signaling pathway_Homo sapiens_hsa049150.83125371
83Insulin signaling pathway_Homo sapiens_hsa049100.81273362
84Ascorbate and aldarate metabolism_Homo sapiens_hsa000530.81185811
85Collecting duct acid secretion_Homo sapiens_hsa049660.79619223
86cGMP-PKG signaling pathway_Homo sapiens_hsa040220.79476773
87Choline metabolism in cancer_Homo sapiens_hsa052310.77587139
88DNA replication_Homo sapiens_hsa030300.77059380
89Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.76804047
90Thyroid hormone synthesis_Homo sapiens_hsa049180.76630004
91Carbohydrate digestion and absorption_Homo sapiens_hsa049730.76600789
92Valine, leucine and isoleucine degradation_Homo sapiens_hsa002800.75986462
93ErbB signaling pathway_Homo sapiens_hsa040120.74452932
94Parkinsons disease_Homo sapiens_hsa050120.74328795
95Oxidative phosphorylation_Homo sapiens_hsa001900.73785366
96Tight junction_Homo sapiens_hsa045300.73068807
97Pancreatic secretion_Homo sapiens_hsa049720.73022520
98Phosphatidylinositol signaling system_Homo sapiens_hsa040700.72458686
99Hedgehog signaling pathway_Homo sapiens_hsa043400.71872991
100Homologous recombination_Homo sapiens_hsa034400.71227170
101Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.70724428
102Dilated cardiomyopathy_Homo sapiens_hsa054140.70711758
103Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010400.70261222
104Adherens junction_Homo sapiens_hsa045200.68876306
105Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005340.68157707
106Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030080.68100441
107Glioma_Homo sapiens_hsa052140.67625864
108Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.67296134
109Fatty acid degradation_Homo sapiens_hsa000710.67087061
110Huntingtons disease_Homo sapiens_hsa050160.66322158
111Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.66254689
112Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001300.66230620
113Sulfur metabolism_Homo sapiens_hsa009200.64172538
114Maturity onset diabetes of the young_Homo sapiens_hsa049500.63634995
115Wnt signaling pathway_Homo sapiens_hsa043100.62831439
116Synthesis and degradation of ketone bodies_Homo sapiens_hsa000720.62194576
117Starch and sucrose metabolism_Homo sapiens_hsa005000.62167518
118Pentose and glucuronate interconversions_Homo sapiens_hsa000400.61145238
119Base excision repair_Homo sapiens_hsa034100.59799975
120Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.58479142
121VEGF signaling pathway_Homo sapiens_hsa043700.58023290
122Vascular smooth muscle contraction_Homo sapiens_hsa042700.57874748
123Axon guidance_Homo sapiens_hsa043600.57406611
124Alzheimers disease_Homo sapiens_hsa050100.57104010
125Phospholipase D signaling pathway_Homo sapiens_hsa040720.56560795
126Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054100.54969704
127AMPK signaling pathway_Homo sapiens_hsa041520.54501670
128Vibrio cholerae infection_Homo sapiens_hsa051100.54453474
129Basal cell carcinoma_Homo sapiens_hsa052170.54387259
130Primary bile acid biosynthesis_Homo sapiens_hsa001200.54131303
131Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.54120650
132Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.53439077
133Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006300.52382192
134Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054120.50137253
135Alcoholism_Homo sapiens_hsa050340.49893751
136Central carbon metabolism in cancer_Homo sapiens_hsa052300.48901166
137Pyruvate metabolism_Homo sapiens_hsa006200.48376679
138TGF-beta signaling pathway_Homo sapiens_hsa043500.47913633
139Glycerolipid metabolism_Homo sapiens_hsa005610.47888058
140Thyroid cancer_Homo sapiens_hsa052160.46920275
141Metabolic pathways_Homo sapiens_hsa011000.46577303
142Purine metabolism_Homo sapiens_hsa002300.44638111
143Biosynthesis of amino acids_Homo sapiens_hsa012300.44231402
144Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.43682446
145Tryptophan metabolism_Homo sapiens_hsa003800.43403158
146Lysine degradation_Homo sapiens_hsa003100.43187569
147Endometrial cancer_Homo sapiens_hsa052130.42149445
148Arginine and proline metabolism_Homo sapiens_hsa003300.41635404
149Fatty acid elongation_Homo sapiens_hsa000620.39812699
150Carbon metabolism_Homo sapiens_hsa012000.38943334
151Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.38605739

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