SLC2A3

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1doxorubicin metabolic process (GO:0044598)8.31751512
2daunorubicin metabolic process (GO:0044597)8.31751512
3polyketide metabolic process (GO:0030638)8.31751512
4protein localization to kinetochore (GO:0034501)6.39725700
5positive regulation of SMAD protein import into nucleus (GO:0060391)6.10233016
6regulation of telomere maintenance via telomerase (GO:0032210)6.09820207
7maintenance of protein location in nucleus (GO:0051457)5.90895127
8nuclear pore complex assembly (GO:0051292)5.86868542
9histone H4-K12 acetylation (GO:0043983)5.68378981
10branching involved in labyrinthine layer morphogenesis (GO:0060670)5.66755851
11negative regulation of G2/M transition of mitotic cell cycle (GO:0010972)5.62960697
12regulation of nuclear cell cycle DNA replication (GO:0033262)5.60553852
13mitotic sister chromatid segregation (GO:0000070)5.50008052
14histone H4-K5 acetylation (GO:0043981)5.48292450
15histone H4-K8 acetylation (GO:0043982)5.48292450
16DNA replication-dependent nucleosome assembly (GO:0006335)5.46874723
17DNA replication-dependent nucleosome organization (GO:0034723)5.46874723
18nuclear pore organization (GO:0006999)5.39843077
19negative regulation of telomerase activity (GO:0051974)5.34535330
20aminoglycoside antibiotic metabolic process (GO:0030647)5.29586585
21regulation of mammary gland epithelial cell proliferation (GO:0033599)5.23831442
22somite rostral/caudal axis specification (GO:0032525)5.19614675
23negative regulation of epidermis development (GO:0045683)5.19454254
24heterochromatin organization (GO:0070828)5.17077392
25embryonic process involved in female pregnancy (GO:0060136)5.14069130
26negative regulation of intracellular estrogen receptor signaling pathway (GO:0033147)5.12352693
27nodal signaling pathway (GO:0038092)5.07654842
28protein localization to chromosome, centromeric region (GO:0071459)5.04659744
29negative regulation of cell cycle G2/M phase transition (GO:1902750)5.03144866
30regulation of gene silencing by RNA (GO:0060966)4.95156519
31regulation of posttranscriptional gene silencing (GO:0060147)4.95156519
32regulation of gene silencing by miRNA (GO:0060964)4.95156519
33regulation of cilium movement (GO:0003352)4.91616683
34pre-miRNA processing (GO:0031054)4.86338341
35paraxial mesoderm development (GO:0048339)4.84991217
36regulation of response to osmotic stress (GO:0047484)4.82631198
37sister chromatid segregation (GO:0000819)4.68501346
38rRNA transcription (GO:0009303)4.58732828
39notochord development (GO:0030903)4.55477388
40chromatin assembly (GO:0031497)4.54441139
41pore complex assembly (GO:0046931)4.38164929
42L-alpha-amino acid transmembrane transport (GO:1902475)4.29685419
43negative regulation of translation involved in gene silencing by miRNA (GO:0035278)4.27872319
44negative regulation of translation, ncRNA-mediated (GO:0040033)4.27872319
45regulation of translation, ncRNA-mediated (GO:0045974)4.27872319
46regulation of Wnt signaling pathway involved in heart development (GO:0003307)4.25315975
47positive regulation of DNA-dependent DNA replication (GO:2000105)4.20806416
48regulation of MHC class I biosynthetic process (GO:0045343)4.14481414
49regulation of mesoderm development (GO:2000380)4.12723052
50muscle organ morphogenesis (GO:0048644)4.11721519
51histone H4-K16 acetylation (GO:0043984)4.08141881
52negative regulation of telomere maintenance (GO:0032205)4.08070898
53negative regulation of epidermal cell differentiation (GO:0045605)4.07060463
54regulation of SMAD protein import into nucleus (GO:0060390)4.02849312
55regulation of translation in response to stress (GO:0043555)3.93643770
56regulation of transcription from RNA polymerase II promoter involved in heart development (GO:1901213.87603129
57female gonad development (GO:0008585)3.84136252
58regulation of gastrulation (GO:0010470)3.83933141
59DNA replication checkpoint (GO:0000076)3.83315058
60cell fate commitment involved in formation of primary germ layer (GO:0060795)3.82639066
61regulation of cell fate specification (GO:0042659)3.75186327
62regulation of stem cell maintenance (GO:2000036)3.73413710
63lung-associated mesenchyme development (GO:0060484)3.71227439
64negative regulation of activin receptor signaling pathway (GO:0032926)3.69562490
65rRNA methylation (GO:0031167)3.69537725
66regulation of telomere maintenance (GO:0032204)3.68461715
67DNA duplex unwinding (GO:0032508)3.66290460
68primitive streak formation (GO:0090009)3.66204529
69SMAD protein signal transduction (GO:0060395)3.65384951
70anterior/posterior axis specification (GO:0009948)3.65225218
71dorsal/ventral axis specification (GO:0009950)3.64283579
72DNA geometric change (GO:0032392)3.63588350
73intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator (GO:0042771)3.62704668
74mRNA stabilization (GO:0048255)3.61169767
75RNA stabilization (GO:0043489)3.61169767
76intestinal epithelial cell development (GO:0060576)3.58305371
77hormone catabolic process (GO:0042447)3.55006632
78branching involved in mammary gland duct morphogenesis (GO:0060444)3.50056916
79rRNA modification (GO:0000154)3.45310469
80mitotic chromosome condensation (GO:0007076)3.45305091
81microtubule severing (GO:0051013)3.44106808
82phenol-containing compound catabolic process (GO:0019336)3.42607883
83response to dietary excess (GO:0002021)3.41623262
84cell surface receptor signaling pathway involved in heart development (GO:0061311)3.38829957
85regulation of activin receptor signaling pathway (GO:0032925)3.37789085
86positive regulation of cardiac muscle cell proliferation (GO:0060045)3.37498443
87regulation of attachment of spindle microtubules to kinetochore (GO:0051988)3.36041193
88regulation of apoptotic process involved in morphogenesis (GO:1902337)3.34008390
89DNA unwinding involved in DNA replication (GO:0006268)3.32778646
90trophectodermal cell differentiation (GO:0001829)3.32241441
91regulation of transforming growth factor beta2 production (GO:0032909)3.30279453
92branching involved in salivary gland morphogenesis (GO:0060445)3.29704048
93regulation of Wnt signaling pathway, planar cell polarity pathway (GO:2000095)3.29051525
94negative regulation of androgen receptor signaling pathway (GO:0060766)3.27405646
95regulation of RNA export from nucleus (GO:0046831)3.27159398
96positive regulation of catenin import into nucleus (GO:0035413)3.26020664
97regulation of hippo signaling (GO:0035330)3.25136960
98protein polyglutamylation (GO:0018095)3.24849058
99nucleoside transmembrane transport (GO:1901642)3.22741977
100mitotic G2/M transition checkpoint (GO:0044818)3.22137095
101bundle of His cell to Purkinje myocyte communication (GO:0086069)3.22116443
102cullin deneddylation (GO:0010388)3.21452510
103regulation of intracellular estrogen receptor signaling pathway (GO:0033146)3.20609379
104spindle assembly (GO:0051225)3.19948986
105digestive tract morphogenesis (GO:0048546)3.19831119
106negative regulation of potassium ion transmembrane transporter activity (GO:1901017)3.19723884
107regulation of microtubule-based movement (GO:0060632)3.19186516
108NLS-bearing protein import into nucleus (GO:0006607)3.17607927
109maintenance of protein localization in organelle (GO:0072595)3.17458085
110establishment of integrated proviral latency (GO:0075713)3.17440675
111maternal placenta development (GO:0001893)3.17331821
112regulation of histone H3-K9 methylation (GO:0051570)3.16851399
113regulation of telomerase activity (GO:0051972)3.16488257
114fusion of sperm to egg plasma membrane (GO:0007342)3.15780296
115regulation of double-strand break repair (GO:2000779)3.15276759
116ribosome biogenesis (GO:0042254)3.15003584
117embryonic axis specification (GO:0000578)3.14912218
118formation of translation preinitiation complex (GO:0001731)3.10541138
119mitotic nuclear envelope disassembly (GO:0007077)3.03873527
120DNA replication initiation (GO:0006270)3.02767995
121positive regulation of protein deacetylation (GO:0090312)3.02714311
122regulation of gene silencing (GO:0060968)3.02261824
123cardiovascular system development (GO:0072358)3.02255813
124negative regulation of cell fate specification (GO:0009996)3.01665477
125cytidine deamination (GO:0009972)3.01464933
126cytidine metabolic process (GO:0046087)3.01464933
127cytidine catabolic process (GO:0006216)3.01464933
128interferon-gamma production (GO:0032609)3.01400708
129negative regulation of histone methylation (GO:0031061)2.98992235
130regulation of odontogenesis of dentin-containing tooth (GO:0042487)2.97972908
131cell migration involved in gastrulation (GO:0042074)2.96804726
132histone H3-K36 demethylation (GO:0070544)2.96762857
133plasma lipoprotein particle assembly (GO:0034377)2.96095981
134histone arginine methylation (GO:0034969)2.95413984
135ventricular system development (GO:0021591)2.94927434
136quinone metabolic process (GO:1901661)2.93442194
137gap junction assembly (GO:0016264)2.92425223
138negative regulation of keratinocyte proliferation (GO:0010839)2.91706382
139anterior/posterior axis specification, embryo (GO:0008595)2.91164086
140regulation of DNA-dependent DNA replication (GO:0090329)2.90977473
141regulation of cell fate commitment (GO:0010453)2.90529383
142DNA conformation change (GO:0071103)2.89070253
143mitochondrial fragmentation involved in apoptotic process (GO:0043653)2.88245041
144negative regulation of gene silencing (GO:0060969)2.88097711
145chromosome condensation (GO:0030261)2.87050129
146signal transduction involved in regulation of gene expression (GO:0023019)2.86589972
147mitotic G2 DNA damage checkpoint (GO:0007095)2.86229331
148intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress (GO:0070059)2.84914988
149establishment of apical/basal cell polarity (GO:0035089)2.83716641
150regulation of chromatin silencing (GO:0031935)2.81773402
151regulation of tight junction assembly (GO:2000810)2.81081290
152regulation of cardioblast differentiation (GO:0051890)2.80879716
153negative regulation of fibroblast apoptotic process (GO:2000270)2.80171760
154hippo signaling (GO:0035329)2.78111734
155phospholipid scrambling (GO:0017121)2.75846155
156positive regulation of cardiac muscle tissue growth (GO:0055023)2.75805496
157neutrophil activation involved in immune response (GO:0002283)2.74708902
158kidney morphogenesis (GO:0060993)2.73109786
159genitalia morphogenesis (GO:0035112)2.72478443
160mRNA transcription from RNA polymerase II promoter (GO:0042789)2.71518194
161regulation of cytokine secretion involved in immune response (GO:0002739)2.67133445
162L-serine metabolic process (GO:0006563)2.64794151
163protein-lipid complex assembly (GO:0065005)2.63677460
164embryonic pattern specification (GO:0009880)2.62313376
165response to BMP (GO:0071772)2.61874395
166cellular response to BMP stimulus (GO:0071773)2.61874395
167protein complex localization (GO:0031503)2.59913847
168regulation of non-canonical Wnt signaling pathway (GO:2000050)2.57126456
169regulation of cardiac muscle cell proliferation (GO:0060043)2.56662648
170respiratory burst (GO:0045730)2.56568856
171cell differentiation involved in embryonic placenta development (GO:0060706)2.53316151
172leukocyte migration involved in inflammatory response (GO:0002523)2.50469455
173regulation of coenzyme metabolic process (GO:0051196)2.49344567
174regulation of cofactor metabolic process (GO:0051193)2.49344567
175regulation of nucleobase-containing compound transport (GO:0032239)2.49000295
176gastrulation with mouth forming second (GO:0001702)2.48241884
177regulation of helicase activity (GO:0051095)2.47314329
178phospholipid efflux (GO:0033700)2.47210483
179cranial suture morphogenesis (GO:0060363)2.46954877
180negative regulation of mRNA metabolic process (GO:1903312)2.46939314
181negative regulation of DNA recombination (GO:0045910)2.46323285
182positive regulation of interleukin-8 biosynthetic process (GO:0045416)2.43873759

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1E2F7_22180533_ChIP-Seq_HELA_Human6.09772763
2* KLF5_18264089_ChIP-ChIP_MESCs_Mouse5.46237806
3* KLF4_18264089_ChIP-ChIP_MESCs_Mouse5.46237806
4* KLF2_18264089_ChIP-ChIP_MESCs_Mouse5.46237806
5CTNNB1_24651522_ChIP-Seq_LGR5+_INTESTINAL_STEM_Human4.18704880
6BP1_19119308_ChIP-ChIP_Hs578T_Human4.18495842
7NOTCH1_17114293_ChIP-ChIP_T-ALL_Human3.51360343
8* NACC1_18358816_ChIP-ChIP_MESCs_Mouse3.43858621
9MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse3.38750808
10POU5F1_18700969_ChIP-ChIP_MESCs_Mouse3.27260173
11* SMAD1_18555785_ChIP-Seq_MESCs_Mouse3.27168446
12FOXM1_23109430_ChIP-Seq_U2OS_Human3.11564629
13E2F4_17652178_ChIP-ChIP_JURKAT_Human3.06802627
14SOX2_18358816_ChIP-ChIP_MESCs_Mouse2.89703840
15SMAD3_22036565_ChIP-Seq_ESCs_Mouse2.82054058
16NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse2.80079498
17TCF3_18692474_ChIP-Seq_MESCs_Mouse2.69503150
18TP63_19390658_ChIP-ChIP_HaCaT_Human2.69396662
19TCF3_18692474_ChIP-Seq_MEFs_Mouse2.57037035
20STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse2.53503979
21* NANOG_18700969_ChIP-ChIP_MESCs_Mouse2.40731101
22* WT1_19549856_ChIP-ChIP_CCG9911_Human2.32787017
23SALL4_18804426_ChIP-ChIP_XEN_Mouse2.29982437
24MYC_18555785_ChIP-Seq_MESCs_Mouse2.24119129
25FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human2.22395818
26SMAD3_21741376_ChIP-Seq_HESCs_Human2.21921810
27ZFP281_18358816_ChIP-ChIP_MESCs_Mouse2.19787789
28ZIC3_20872845_ChIP-ChIP_MESCs_Mouse2.11158007
29NANOG_18358816_ChIP-ChIP_MESCs_Mouse2.10770824
30STAT3_1855785_ChIP-Seq_MESCs_Mouse2.10580575
31NANOG_18347094_ChIP-ChIP_MESCs_Mouse2.08059711
32TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat2.05958827
33* MYC_19079543_ChIP-ChIP_MESCs_Mouse2.05349921
34FOXP3_17237761_ChIP-ChIP_TREG_Mouse2.05023742
35POU5F1_18358816_ChIP-ChIP_MESCs_Mouse1.98040404
36NANOG_18555785_ChIP-Seq_MESCs_Mouse1.91657631
37* KLF4_18358816_ChIP-ChIP_MESCs_Mouse1.90208113
38SOX2_18555785_ChIP-Seq_MESCs_Mouse1.87980899
39SALL4_18804426_ChIP-ChIP_MESCs_Mouse1.84830639
40* POU5F1_16518401_ChIP-PET_MESCs_Mouse1.82108275
41MYBL2_22936984_ChIP-ChIP_MESCs_Mouse1.81928157
42* MYC_19030024_ChIP-ChIP_MESCs_Mouse1.80971009
43* NR0B1_18358816_ChIP-ChIP_MESCs_Mouse1.80111157
44POU5F1_18555785_ChIP-Seq_MESCs_Mouse1.74163891
45* TCF3_18347094_ChIP-ChIP_MESCs_Mouse1.66127478
46STAT3_20064451_ChIP-Seq_CD4+T_Mouse1.65428661
47* KDM5B_21448134_ChIP-Seq_MESCs_Mouse1.63301141
48* CHD1_19587682_ChIP-ChIP_MESCs_Mouse1.61264275
49CLOCK_20551151_ChIP-Seq_293T_Human1.61031242
50IRF1_19129219_ChIP-ChIP_H3396_Human1.58342381
51RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.58185060
52* NANOG_18692474_ChIP-Seq_MESCs_Mouse1.56718070
53* SMAD4_21741376_ChIP-Seq_HESCs_Human1.55046343
54* NANOG_18692474_ChIP-Seq_MEFs_Mouse1.51519009
55* POU5F1_18692474_ChIP-Seq_MESCs_Mouse1.49754295
56EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse1.48210408
57* SOX2_18692474_ChIP-Seq_MESCs_Mouse1.46725479
58* MYC_18358816_ChIP-ChIP_MESCs_Mouse1.46541839
59MYB_21317192_ChIP-Seq_ERMYB_Mouse1.45368347
60* PRDM14_21183938_ChIP-Seq_MESCs_Mouse1.44573271
61Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse1.39377494
62TCF3_18467660_ChIP-ChIP_MESCs_Mouse1.39152132
63E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse1.37795396
64* ZFP281_18757296_ChIP-ChIP_E14_Mouse1.36370228
65* HIF1A_21447827_ChIP-Seq_MCF-7_Human1.35450566
66SMARCA4_20176728_ChIP-ChIP_TSCs_Mouse1.34794260
67EOMES_21245162_ChIP-Seq_HESCs_Human1.33025306
68ZFP281_27345836_Chip-Seq_ESCs_Mouse1.32060194
69MYC_22102868_ChIP-Seq_BL_Human1.31248019
70YY1_21170310_ChIP-Seq_MESCs_Mouse1.30450340
71STAT6_20620947_ChIP-Seq_CD4_POS_T_Human1.29738263
72* OCT4_18692474_ChIP-Seq_MEFs_Mouse1.29448931
73* SOX2_18692474_ChIP-Seq_MEFs_Mouse1.26706829
74* NANOG_16518401_ChIP-PET_MESCs_Mouse1.25033556
75E2F1_17053090_ChIP-ChIP_MCF-7_Human1.22454539
76ASXL1_24218140_ChIP-Seq_BMDM_Mouse1.21857851
77HOXD13_18407260_ChIP-ChIP_DEVELOPING-LIMBS_Mouse1.20253132
78* NANOG_21062744_ChIP-ChIP_HESCs_Human1.18506868
79CREB1_15753290_ChIP-ChIP_HEK293T_Human1.18354416
80TRIM28_17542650_ChIP-ChIP_NTERA2_Human1.18117039
81PPARG_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse1.18111804
82* ISL1_27105846_Chip-Seq_CPCs_Mouse1.16323548
83FLI1_27457419_Chip-Seq_LIVER_Mouse1.15720968
84ZFP42_18358816_ChIP-ChIP_MESCs_Mouse1.14840090
85PRDM5_23873026_ChIP-Seq_MEFs_Mouse1.14561253
86NANOG_16153702_ChIP-ChIP_HESCs_Human1.13926032
87POU5F1_18347094_ChIP-ChIP_MESCs_Mouse1.12233039
88* EOMES_20176728_ChIP-ChIP_TSCs_Mouse1.10994455
89KLF4_18555785_ChIP-Seq_MESCs_Mouse1.10098009
90HOXB4_20404135_ChIP-ChIP_EML_Mouse1.07516803
91MYCN_18555785_ChIP-Seq_MESCs_Mouse1.05491906
92PPARG_20176806_ChIP-Seq_MACROPHAGES_Mouse1.05048733
93SMAD4_19686287_ChIP-ChIP_HaCaT_Human1.03753883
94SALL1_21062744_ChIP-ChIP_HESCs_Human1.03353596
95ESR1_21235772_ChIP-Seq_MCF-7_Human1.01530732
96AR_21909140_ChIP-Seq_LNCAP_Human0.99547753
97KAP1_27257070_Chip-Seq_ESCs_Mouse0.99337507
98* STAT3_24763339_ChIP-Seq_IMN-ESCs_Mouse0.99317221
99EGR1_19374776_ChIP-ChIP_THP-1_Human0.98891995
100* NELFA_20434984_ChIP-Seq_ESCs_Mouse0.97574450
101* KLF4_19030024_ChIP-ChIP_MESCs_Mouse0.96974393
102P300_19829295_ChIP-Seq_ESCs_Human0.96699015
103EST1_17652178_ChIP-ChIP_JURKAT_Human0.96624099
104ESR1_15608294_ChIP-ChIP_MCF-7_Human0.96129712
105IRF8_27001747_Chip-Seq_BMDM_Mouse0.95723043
106* E2F1_18555785_ChIP-Seq_MESCs_Mouse0.95235376
107TP53_22127205_ChIP-Seq_IMR90_Human0.94324984
108XRN2_22483619_ChIP-Seq_HELA_Human0.94267666
109SOX17_20123909_ChIP-Seq_XEN_Mouse0.91775211
110NCOR1_26117541_ChIP-Seq_K562_Human0.89815472
111SIN3A_21632747_ChIP-Seq_MESCs_Mouse0.88200111
112PCGF2_27294783_Chip-Seq_ESCs_Mouse0.87749045
113RBPJ_22232070_ChIP-Seq_NCS_Mouse0.87709445
114TBX3_20139965_ChIP-Seq_ESCs_Mouse0.87433327
115TBX3_20139965_ChIP-Seq_MESCs_Mouse0.85906241
116ZFP322A_24550733_ChIP-Seq_MESCs_Mouse0.85652113
117MECOM_23826213_ChIP-Seq_KASUMI_Mouse0.84775312
118SOX2_16153702_ChIP-ChIP_HESCs_Human0.84420211
119KDM5A_27292631_Chip-Seq_BREAST_Human0.83060297
120KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human0.82947832
121PU_27001747_Chip-Seq_BMDM_Mouse0.82079531
122MYCN_21190229_ChIP-Seq_SHEP-21N_Human0.81144550
123TCF7_22412390_ChIP-Seq_EML_Mouse0.80308420
124NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse0.80122928
125HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse0.79857361
126CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat0.79076879
127GATA1_26923725_Chip-Seq_HPCs_Mouse0.78765202
128ELK1_19687146_ChIP-ChIP_HELA_Human0.78641079
129EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse0.78408908
130SOX2_19030024_ChIP-ChIP_MESCs_Mouse0.77977742
131* FOXP3_21729870_ChIP-Seq_TREG_Human0.76847570
132SMAD3_21741376_ChIP-Seq_EPCs_Human0.75919991
133POU5F1_16153702_ChIP-ChIP_HESCs_Human0.75689196
134SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse0.75276423
135RCOR2_21632747_ChIP-Seq_MESCs_Mouse0.74878623
136* STAT3_18555785_ChIP-Seq_MESCs_Mouse0.73016843
137NOTCH1_21737748_ChIP-Seq_TLL_Human0.72249762
138TTF2_22483619_ChIP-Seq_HELA_Human0.71758610
139* RCOR3_21632747_ChIP-Seq_MESCs_Mouse0.70984853
140ASH2L_23239880_ChIP-Seq_MESCs_Mouse0.70871584
141TFAP2A_17053090_ChIP-ChIP_MCF-7_Human0.70737866
142ZFX_18555785_ChIP-Seq_MESCs_Mouse0.70061875
143CDX2_20551321_ChIP-Seq_CACO-2_Human0.68740266

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0002254_reproductive_system_inflammat3.97380598
2MP0008057_abnormal_DNA_replication3.88523513
3MP0008004_abnormal_stomach_pH3.85645309
4MP0006292_abnormal_olfactory_placode3.68492325
5MP0003011_delayed_dark_adaptation3.66553143
6MP0003941_abnormal_skin_development3.57097272
7MP0003890_abnormal_embryonic-extraembry3.54877004
8MP0004957_abnormal_blastocyst_morpholog3.30496572
9MP0003878_abnormal_ear_physiology3.26068156
10MP0005377_hearing/vestibular/ear_phenot3.26068156
11MP0002653_abnormal_ependyma_morphology3.12555238
12MP0003567_abnormal_fetal_cardiomyocyte2.86387975
13MP0006054_spinal_hemorrhage2.75870694
14MP0003122_maternal_imprinting2.75562931
15MP0004858_abnormal_nervous_system2.74356761
16MP0003121_genomic_imprinting2.62908118
17MP0005499_abnormal_olfactory_system2.61693785
18MP0005394_taste/olfaction_phenotype2.61693785
19MP0005075_abnormal_melanosome_morpholog2.44682107
20MP0010352_gastrointestinal_tract_polyps2.43431407
21MP0003705_abnormal_hypodermis_morpholog2.30161513
22MP0003123_paternal_imprinting2.26405968
23MP0009672_abnormal_birth_weight2.24170379
24MP0002332_abnormal_exercise_endurance2.22485871
25MP0005410_abnormal_fertilization2.21294615
26MP0001672_abnormal_embryogenesis/_devel2.20275857
27MP0005380_embryogenesis_phenotype2.20275857
28MP0004272_abnormal_basement_membrane2.15854517
29MP0003077_abnormal_cell_cycle2.14111197
30MP0003111_abnormal_nucleus_morphology2.08773734
31MP0010094_abnormal_chromosome_stability2.08546658
32MP0002088_abnormal_embryonic_growth/wei1.98996920
33MP0003984_embryonic_growth_retardation1.97997279
34* MP0004264_abnormal_extraembryonic_tissu1.96538086
35MP0004133_heterotaxia1.92610856
36MP0001293_anophthalmia1.89907417
37MP0000350_abnormal_cell_proliferation1.82912641
38MP0006035_abnormal_mitochondrial_morpho1.82516976
39MP0005257_abnormal_intraocular_pressure1.71037399
40MP0002084_abnormal_developmental_patter1.70948667
41MP0002085_abnormal_embryonic_tissue1.65923290
42MP0002086_abnormal_extraembryonic_tissu1.65582051
43MP0003283_abnormal_digestive_organ1.65488561
44MP0008260_abnormal_autophagy1.62167060
45MP0003119_abnormal_digestive_system1.59989391
46MP0003938_abnormal_ear_development1.59067536
47MP0003566_abnormal_cell_adhesion1.57421294
48MP0001849_ear_inflammation1.56562032
49MP0000678_abnormal_parathyroid_gland1.56163378
50MP0001730_embryonic_growth_arrest1.54412654
51MP0000537_abnormal_urethra_morphology1.53312576
52MP0002127_abnormal_cardiovascular_syste1.48868281
53MP0004197_abnormal_fetal_growth/weight/1.45375577
54MP0009278_abnormal_bone_marrow1.44667200
55MP0003693_abnormal_embryo_hatching1.44464989
56MP0005367_renal/urinary_system_phenotyp1.44097779
57MP0000516_abnormal_urinary_system1.44097779
58MP0010030_abnormal_orbit_morphology1.43420544
59MP0002092_abnormal_eye_morphology1.43260656
60MP0008961_abnormal_basal_metabolism1.38055920
61MP0003787_abnormal_imprinting1.36844256
62MP0005076_abnormal_cell_differentiation1.34685955
63MP0001697_abnormal_embryo_size1.33939641
64MP0003724_increased_susceptibility_to1.33017844
65MP0005266_abnormal_metabolism1.26359042
66MP0008007_abnormal_cellular_replicative1.24960883
67MP0008932_abnormal_embryonic_tissue1.24851931
68MP0003303_peritoneal_inflammation1.24103922
69MP0003221_abnormal_cardiomyocyte_apopto1.21365589
70MP0001915_intracranial_hemorrhage1.20486093
71MP0005623_abnormal_meninges_morphology1.17289963
72MP0002080_prenatal_lethality1.16535436
73MP0000647_abnormal_sebaceous_gland1.15426510
74MP0002277_abnormal_respiratory_mucosa1.10800554
75MP0000432_abnormal_head_morphology1.10685761
76MP0002932_abnormal_joint_morphology1.09268395
77MP0000313_abnormal_cell_death1.09015018
78MP0010307_abnormal_tumor_latency1.08289521
79MP0008058_abnormal_DNA_repair1.07552590
80MP0000049_abnormal_middle_ear1.07299961
81MP0003315_abnormal_perineum_morphology1.06923647
82MP0002233_abnormal_nose_morphology1.06374545
83MP0008789_abnormal_olfactory_epithelium1.06154920
84MP0001145_abnormal_male_reproductive1.06044203
85MP0000428_abnormal_craniofacial_morphol1.05117517
86MP0000762_abnormal_tongue_morphology1.04982904
87MP0003698_abnormal_male_reproductive1.04188055
88MP0010630_abnormal_cardiac_muscle1.03175902
89MP0001929_abnormal_gametogenesis1.02960451
90MP0002114_abnormal_axial_skeleton1.02875105
91MP0003385_abnormal_body_wall1.01265844
92MP0008770_decreased_survivor_rate1.00806474
93MP0009703_decreased_birth_body0.98550430
94MP0003183_abnormal_peptide_metabolism0.96796455
95MP0003786_premature_aging0.95977101
96MP0000490_abnormal_crypts_of0.94831162
97MP0002210_abnormal_sex_determination0.94595658
98MP0003935_abnormal_craniofacial_develop0.94471746
99MP0002396_abnormal_hematopoietic_system0.94194127
100MP0002925_abnormal_cardiovascular_devel0.91386442
101MP0005391_vision/eye_phenotype0.90675663
102MP0001348_abnormal_lacrimal_gland0.90383798
103MP0002138_abnormal_hepatobiliary_system0.88841809
104MP0003861_abnormal_nervous_system0.87265835
105MP0005671_abnormal_response_to0.85999758
106MP0001614_abnormal_blood_vessel0.85537057
107MP0003755_abnormal_palate_morphology0.84880038
108MP0000383_abnormal_hair_follicle0.84711967
109MP0001853_heart_inflammation0.83727356
110MP0000358_abnormal_cell_content/0.82841747
111MP0003937_abnormal_limbs/digits/tail_de0.82248498
112MP0002009_preneoplasia0.80540935
113MP0005464_abnormal_platelet_physiology0.78756113
114MP0002970_abnormal_white_adipose0.78561910
115MP0001286_abnormal_eye_development0.78317247
116MP0001177_atelectasis0.78265257
117MP0002269_muscular_atrophy0.77653024
118MP0002998_abnormal_bone_remodeling0.77011272
119MP0005248_abnormal_Harderian_gland0.76004284
120MP0002796_impaired_skin_barrier0.75493445
121MP0002132_abnormal_respiratory_system0.74641264
122MP0003828_pulmonary_edema0.74637726
123MP0002419_abnormal_innate_immunity0.74061125
124MP0005023_abnormal_wound_healing0.73208378
125MP0002111_abnormal_tail_morphology0.70719178
126MP0008877_abnormal_DNA_methylation0.70561222
127MP0002249_abnormal_larynx_morphology0.70385540
128MP0005384_cellular_phenotype0.69839880
129MP0003943_abnormal_hepatobiliary_system0.68881251
130MP0002116_abnormal_craniofacial_bone0.68579245
131MP0002697_abnormal_eye_size0.67402755
132MP0010678_abnormal_skin_adnexa0.67078504
133MP0006082_CNS_inflammation0.66599285
134MP0000689_abnormal_spleen_morphology0.64244876
135MP0002751_abnormal_autonomic_nervous0.63968508
136MP0000653_abnormal_sex_gland0.61981924
137MP0000266_abnormal_heart_morphology0.61389213
138MP0004043_abnormal_pH_regulation0.61231607
139MP0003136_yellow_coat_color0.60544646
140MP0004947_skin_inflammation0.60429294
141MP0002722_abnormal_immune_system0.60260772
142MP0001175_abnormal_lung_morphology0.60025012
143* MP0002081_perinatal_lethality0.59952671
144MP0003436_decreased_susceptibility_to0.59795052
145MP0003448_altered_tumor_morphology0.58567657
146MP0002098_abnormal_vibrissa_morphology0.58076708
147MP0009333_abnormal_splenocyte_physiolog0.57450921
148MP0003115_abnormal_respiratory_system0.57265350

Predicted human phenotypes

RankGene SetZ-score
1Bilateral microphthalmos (HP:0007633)6.66341199
2Abnormality of the lower motor neuron (HP:0002366)5.60542074
3Hypochromic microcytic anemia (HP:0004840)5.60383250
4Ependymoma (HP:0002888)5.09234609
5Hepatoblastoma (HP:0002884)4.80641817
6Multiple enchondromatosis (HP:0005701)4.41362377
7Rib fusion (HP:0000902)4.29115796
8Absent eyebrow (HP:0002223)4.15956489
9Anal stenosis (HP:0002025)3.96907971
10Neoplasm of striated muscle (HP:0009728)3.95569552
11Chromosomal breakage induced by crosslinking agents (HP:0003221)3.94240508
12Nephroblastoma (Wilms tumor) (HP:0002667)3.92923591
13Rhabdomyosarcoma (HP:0002859)3.90579672
14Myelomeningocele (HP:0002475)3.85773892
15Intestinal atresia (HP:0011100)3.76960631
16Aqueductal stenosis (HP:0002410)3.75198752
17Amyotrophic lateral sclerosis (HP:0007354)3.71620091
18Astrocytoma (HP:0009592)3.68601080
19Abnormality of the astrocytes (HP:0100707)3.68601080
20Embryonal renal neoplasm (HP:0011794)3.65423386
21Septo-optic dysplasia (HP:0100842)3.45113089
22Chromsome breakage (HP:0040012)3.45051697
23Choanal stenosis (HP:0000452)3.39540661
24Supernumerary spleens (HP:0009799)3.31505303
25Stenosis of the external auditory canal (HP:0000402)3.18811347
26Aplasia/hypoplasia of the humerus (HP:0006507)3.17917108
27Abnormality of the salivary glands (HP:0010286)3.16974102
28Short humerus (HP:0005792)3.16908054
29Fused cervical vertebrae (HP:0002949)3.15997429
30Impulsivity (HP:0100710)3.10849250
31Chin dimple (HP:0010751)3.07669714
32Congenital malformation of the right heart (HP:0011723)3.06263889
33Double outlet right ventricle (HP:0001719)3.06263889
34Abnormal lung lobation (HP:0002101)2.93007622
35Testicular atrophy (HP:0000029)2.87925912
36Rectal fistula (HP:0100590)2.83994234
37Rectovaginal fistula (HP:0000143)2.83994234
38Anophthalmia (HP:0000528)2.83736575
39Hyperinsulinemic hypoglycemia (HP:0000825)2.79528457
40Deep palmar crease (HP:0006191)2.79162188
41Meckel diverticulum (HP:0002245)2.78759659
42Glioma (HP:0009733)2.76950023
43Cupped ear (HP:0000378)2.76209063
44Absent radius (HP:0003974)2.76009519
45Abnormal pancreas size (HP:0012094)2.74104358
46Agnosia (HP:0010524)2.71262937
47Horizontal nystagmus (HP:0000666)2.66347880
48Upper motor neuron abnormality (HP:0002127)2.66289683
49Abnormality of the parathyroid morphology (HP:0011766)2.66180240
50Shawl scrotum (HP:0000049)2.64699537
51Bifid tongue (HP:0010297)2.64355540
52Trismus (HP:0000211)2.64175786
53Hypoplasia of the fovea (HP:0007750)2.62340137
54Aplasia/Hypoplasia of the fovea (HP:0008060)2.62340137
55Medulloblastoma (HP:0002885)2.61820427
56Abnormality of the ileum (HP:0001549)2.61448788
57Aplasia/Hypoplasia of the uvula (HP:0010293)2.61016027
58Gastrointestinal carcinoma (HP:0002672)2.60448429
59Malignant gastrointestinal tract tumors (HP:0006749)2.60448429
60Esophageal atresia (HP:0002032)2.56776128
61Absent forearm bone (HP:0003953)2.55825773
62Aplasia involving forearm bones (HP:0009822)2.55825773
63Pancreatic islet-cell hyperplasia (HP:0004510)2.54980163
64Short hallux (HP:0010109)2.54962882
65Ragged-red muscle fibers (HP:0003200)2.54874483
66Skull defect (HP:0001362)2.53765509
67Mixed hearing impairment (HP:0000410)2.52254984
68Intestinal fistula (HP:0100819)2.51904091
69Breast aplasia (HP:0100783)2.51299281
70Partial duplication of thumb phalanx (HP:0009944)2.48326350
71Abnormality of the pubic bones (HP:0003172)2.45763995
72Aplasia/Hypoplasia of the sternum (HP:0006714)2.44268676
73Labial hypoplasia (HP:0000066)2.44166647
74Preauricular skin tag (HP:0000384)2.43214252
75Omphalocele (HP:0001539)2.43165544
76Respiratory insufficiency due to defective ciliary clearance (HP:0200073)2.43156236
77Missing ribs (HP:0000921)2.42803690
78Transposition of the great arteries (HP:0001669)2.39009275
79Abnormal connection of the cardiac segments (HP:0011545)2.39009275
80Abnormal ventriculo-arterial connection (HP:0011563)2.39009275
81Progressive inability to walk (HP:0002505)2.38891462
82Vaginal fistula (HP:0004320)2.38083686
83Nuclear cataract (HP:0100018)2.36323851
84Aplasia/Hypoplasia of the hallux (HP:0008362)2.35221444
85Oligodactyly (hands) (HP:0001180)2.34126319
86Hypoplastic female external genitalia (HP:0012815)2.32903496
87Hypopigmentation of the fundus (HP:0007894)2.31610678
88Short middle phalanx of the 5th finger (HP:0004220)2.30903269
89Neoplasm of the oral cavity (HP:0100649)2.30327900
90Atrophy/Degeneration involving motor neurons (HP:0007373)2.29027318
91Large earlobe (HP:0009748)2.28489065
92Horseshoe kidney (HP:0000085)2.28053779
93Abnormality of chromosome segregation (HP:0002916)2.27606562
94Hereditary nonpolyposis colorectal carcinoma (HP:0006716)2.25122136
95Stomatitis (HP:0010280)2.25117020
96Vitreoretinal degeneration (HP:0000655)2.24215475
97Preaxial foot polydactyly (HP:0001841)2.23180304
98Pseudobulbar signs (HP:0002200)2.23096093
99Skin tags (HP:0010609)2.21301896
100Absent eyelashes (HP:0000561)2.21249606
101Small intestinal stenosis (HP:0012848)2.18497426
102Duodenal stenosis (HP:0100867)2.18497426
103Transitional cell carcinoma of the bladder (HP:0006740)2.18150221
104Facial cleft (HP:0002006)2.17342924
105Broad thumb (HP:0011304)2.16915543
106Supernumerary ribs (HP:0005815)2.14981892
107Partial duplication of the phalanx of hand (HP:0009999)2.14505410
108Colon cancer (HP:0003003)2.14287753
109Abnormal cartilage morphology (HP:0002763)2.14050104
110Hypochromic anemia (HP:0001931)2.13817940
111Abnormality of the musculature of the hand (HP:0001421)2.13380137
112Nasal polyposis (HP:0100582)2.13263969
113Difficulty running (HP:0009046)2.12902138
114Aplasia/Hypoplasia of the breasts (HP:0010311)2.12075289
115Erectile abnormalities (HP:0100639)2.11707735
116Resting tremor (HP:0002322)2.11685554
117Carpal bone hypoplasia (HP:0001498)2.10621628
118Malignant neoplasm of the central nervous system (HP:0100836)2.10479912
119Abnormality of the nasal septum (HP:0000419)2.09508005
120Curly hair (HP:0002212)2.09439699
121Cellular immunodeficiency (HP:0005374)2.09228004
122Bicornuate uterus (HP:0000813)2.07640841
123Spastic diplegia (HP:0001264)2.07151564
124Ectopic anus (HP:0004397)2.06227884
125Generalized hypotonia (HP:0001290)2.05977519
126Anomalous pulmonary venous return (HP:0010772)2.05604304
127Selective tooth agenesis (HP:0001592)2.05486025
128Tetraplegia (HP:0002445)2.05346077
129Leiomyosarcoma (HP:0100243)2.04744592
130Uterine leiomyosarcoma (HP:0002891)2.04744592
131Biliary tract neoplasm (HP:0100574)2.03794179
132Uterine neoplasm (HP:0010784)2.03530803
133Hand muscle atrophy (HP:0009130)2.02868277
134Pendular nystagmus (HP:0012043)2.01252946
135Sensory axonal neuropathy (HP:0003390)2.01171018
136Neoplasm of the heart (HP:0100544)2.01048052
137Abnormality of macrophages (HP:0004311)2.00970809
138Abnormality of the septum pellucidum (HP:0007375)2.00777408
139Renal duplication (HP:0000075)2.00754487
140Vertebral fusion (HP:0002948)2.00191956
141Progressive muscle weakness (HP:0003323)1.97741783
142Supernumerary bones of the axial skeleton (HP:0009144)1.96501970
143Hemivertebrae (HP:0002937)1.95144477
144Right ventricular cardiomyopathy (HP:0011663)1.94974364
145Aplasia/Hypoplasia of the phalanges of the 5th finger (HP:0009376)1.94713561
146Maternal diabetes (HP:0009800)1.94646336
147Aplasia/Hypoplasia of the macula (HP:0008059)1.93942162
148Abnormality of the phalanges of the hallux (HP:0010057)1.93811077
149Abnormality of the labia minora (HP:0012880)1.92579409
150Absent hair (HP:0002298)1.92074083
151Embryonal neoplasm (HP:0002898)1.91621775
152Abnormality of the fovea (HP:0000493)1.90131603
153Increased connective tissue (HP:0009025)1.90043978
154Preauricular pit (HP:0004467)1.89379622
155Periauricular skin pits (HP:0100277)1.89379622
156Premature ovarian failure (HP:0008209)1.89372510
157Amaurosis fugax (HP:0100576)1.89312106
158Abnormality of the lacrimal duct (HP:0011481)1.89294347
159Myocardial infarction (HP:0001658)1.88869667
160Abnormality of the distal phalanx of the thumb (HP:0009617)1.88817218
161Cutaneous syndactyly (HP:0012725)1.87994249
162Sloping forehead (HP:0000340)1.87986575
163Reduced antithrombin III activity (HP:0001976)1.87788980
164Bladder carcinoma (HP:0002862)1.86213343
165Bladder neoplasm (HP:0009725)1.86213343
166Abnormality of the preputium (HP:0100587)1.85226724
167Renal hypoplasia (HP:0000089)1.85225378
168Glossoptosis (HP:0000162)1.84334176
169Aplasia/Hypoplasia of the middle phalanx of the 5th finger (HP:0009161)1.84148861
170Tongue fasciculations (HP:0001308)1.83394595
171Abnormality of the duodenum (HP:0002246)1.82123122
172Absent septum pellucidum (HP:0001331)1.81314656
173Short 5th finger (HP:0009237)1.80996562
174Adenoma sebaceum (HP:0009720)1.80774034
175Angiofibromas (HP:0010615)1.80774034
176Tetraparesis (HP:0002273)1.80326476
177Ankyloglossia (HP:0010296)1.80001270
178Clitoromegaly (HP:0000057)1.79695552
179Aplasia/Hypoplasia of the optic nerve (HP:0008058)1.79079976
180Decreased number of large peripheral myelinated nerve fibers (HP:0003387)1.78964361
181Abdominal situs inversus (HP:0003363)1.78721753
182Abnormality of abdominal situs (HP:0011620)1.78721753

Predicted kinase interactions (KEA)

RankGene SetZ-score
1CDK128.73308821
2LATS14.14628687
3ERBB44.12678317
4GRK54.08502362
5ERN13.58552293
6TNIK3.52748815
7TTK3.28948822
8GRK63.23504022
9MST43.02455041
10TYRO32.87945774
11STK38L2.60080370
12EPHA22.52268593
13TSSK62.39957605
14CSF1R2.38830280
15MKNK22.30737897
16STK102.16703777
17MKNK12.13375672
18ADRBK22.09831473
19FGR2.09294443
20GRK12.07835957
21MAPK72.07607717
22WNK12.03496875
23SIK32.00371788
24TRIM281.97655997
25MATK1.94507385
26TGFBR21.90875786
27GRK71.87959998
28PBK1.82443840
29PDK41.81756083
30PDK31.81756083
31CDK71.79302136
32CDC71.77697176
33NLK1.76141985
34FGFR11.70541211
35ACVR1B1.67346524
36MOS1.63237957
37CHEK21.58720684
38PLK41.57102724
39AKT31.55921363
40WEE11.53700347
41NEK21.52244041
42FGFR21.50516344
43PLK11.44615860
44PAK41.43187542
45PLK31.42194997
46YES11.34498756
47NME11.33393978
48NTRK11.27463649
49OXSR11.25513828
50TIE11.24319805
51PRKG21.18721578
52PDK21.18664563
53CDK191.17044417
54CHEK11.15615809
55CAMK41.11780452
56FGFR41.09787654
57NEK11.09548466
58RPS6KB21.09426731
59MARK21.08567141
60BCR1.08107407
61BUB11.07138311
62STK241.02255868
63RPS6KA40.97961405
64MAP2K40.95084812
65ALK0.94690024
66LATS20.94189207
67ICK0.92165513
68MAP3K100.91284832
69PKN20.89294972
70MAP3K130.83891370
71EIF2AK30.82712126
72FES0.81757334
73MTOR0.80601037
74AKT20.80425952
75MAP3K90.79901494
76ADRBK10.75622172
77CAMK1D0.75408017
78FGFR30.74896269
79HIPK20.73031036
80IRAK40.71876623
81PIM10.70514624
82CDK20.70298965
83ZAK0.69906848
84MAP3K140.65674126
85ATM0.65527477
86AURKA0.65374598
87PLK20.64850560
88CDK40.64847808
89BLK0.61931032
90CAMK1G0.61848239
91TAF10.60005020
92EGFR0.58412818
93PRKCI0.57706115
94BRD40.57565043
95CSK0.56980944
96WNK30.56435479
97STK380.56328037
98MAP2K60.55812826
99BRSK20.55755203
100CDK60.55685431
101AURKB0.55432037
102TEC0.55385008
103ATR0.50892961
104TXK0.50841419
105SRPK10.49578359
106BMPR1B0.48966802
107CSNK1E0.48893463
108PAK10.48142176
109PRKD30.45430561
110EIF2AK20.45400990
111CDK10.43582974
112PTK20.43476032
113PDGFRB0.42789982
114TGFBR10.42456754
115CLK10.40125552
116KSR10.39680211
117RIPK40.38972433
118MAP3K70.37302008
119TESK20.37173812
120STK390.37154417
121NEK60.37025399
122NUAK10.36545454
123MAPK100.36130548
124DYRK30.36109184
125MELK0.35154060
126MAP3K80.35052822
127RIPK10.34319398
128IRAK10.32831804
129PNCK0.32327522
130TESK10.30947454
131GSK3B0.30776708
132PASK0.30247912
133PDGFRA0.28987115
134JAK30.28641263
135MAPK140.28485328
136MAPK10.28232896
137CSNK1D0.28148372
138MAPK120.27312509
139BMX0.27038035
140SCYL20.26744935
141CDK150.26073296
142HCK0.25144663
143MAPKAPK30.25031281
144ZAP700.24797976
145LCK0.24486720
146IRAK20.24093292
147CDK11A0.23683266
148MET0.23413554
149JAK20.23328962
150INSR0.22639426
151FLT30.22586145
152CDK180.21681322
153EEF2K0.21629221
154ERBB20.21329124
155STK40.20003029
156IGF1R0.19752093
157LYN0.19154739
158TLK10.18345552
159KDR0.18019028
160STK30.17866896
161PAK60.17647249
162PRKACB0.15380621
163CDK140.14346556
164PAK20.13950639
165AKT10.13533788

Predicted pathways (KEGG)

RankGene SetZ-score
1Vitamin B6 metabolism_Homo sapiens_hsa007505.40616159
2Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006034.79699697
3Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030084.48828643
4Fructose and mannose metabolism_Homo sapiens_hsa000513.59985650
5RNA transport_Homo sapiens_hsa030132.86747080
6Fanconi anemia pathway_Homo sapiens_hsa034602.38924443
7Mismatch repair_Homo sapiens_hsa034302.33543269
8DNA replication_Homo sapiens_hsa030302.32701666
9mRNA surveillance pathway_Homo sapiens_hsa030152.20212499
10Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009702.18903793
11Legionellosis_Homo sapiens_hsa051342.15273443
12Galactose metabolism_Homo sapiens_hsa000522.15244797
13One carbon pool by folate_Homo sapiens_hsa006702.01012253
14Pantothenate and CoA biosynthesis_Homo sapiens_hsa007702.00034194
15Cell cycle_Homo sapiens_hsa041101.90818733
16Arachidonic acid metabolism_Homo sapiens_hsa005901.78989756
17Steroid biosynthesis_Homo sapiens_hsa001001.77613001
18Glycolysis / Gluconeogenesis_Homo sapiens_hsa000101.71474253
19Homologous recombination_Homo sapiens_hsa034401.69342785
20Spliceosome_Homo sapiens_hsa030401.66452582
21mTOR signaling pathway_Homo sapiens_hsa041501.60307533
22Linoleic acid metabolism_Homo sapiens_hsa005911.60163656
23Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045501.57832764
24Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005331.57562920
25HIF-1 signaling pathway_Homo sapiens_hsa040661.57057648
26Ubiquitin mediated proteolysis_Homo sapiens_hsa041201.53979353
27alpha-Linolenic acid metabolism_Homo sapiens_hsa005921.51244973
28RNA degradation_Homo sapiens_hsa030181.50140780
29Thyroid cancer_Homo sapiens_hsa052161.47970504
30Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009801.47841419
31Vitamin digestion and absorption_Homo sapiens_hsa049771.44305763
32Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005201.43401768
33NOD-like receptor signaling pathway_Homo sapiens_hsa046211.35600560
34Pathogenic Escherichia coli infection_Homo sapiens_hsa051301.32626971
35Basal cell carcinoma_Homo sapiens_hsa052171.30199976
36Central carbon metabolism in cancer_Homo sapiens_hsa052301.22102594
37Endometrial cancer_Homo sapiens_hsa052131.21849220
38Hedgehog signaling pathway_Homo sapiens_hsa043401.17691597
39Basal transcription factors_Homo sapiens_hsa030221.16611853
40Amoebiasis_Homo sapiens_hsa051461.15683721
41Base excision repair_Homo sapiens_hsa034101.14470279
42p53 signaling pathway_Homo sapiens_hsa041151.11147099
43Pentose phosphate pathway_Homo sapiens_hsa000301.10264374
44Osteoclast differentiation_Homo sapiens_hsa043801.07472671
45Glycine, serine and threonine metabolism_Homo sapiens_hsa002601.06094344
46Prostate cancer_Homo sapiens_hsa052151.02872625
47Nucleotide excision repair_Homo sapiens_hsa034201.02239653
48Hippo signaling pathway_Homo sapiens_hsa043901.01110070
49Ribosome_Homo sapiens_hsa030101.00303427
50Biosynthesis of amino acids_Homo sapiens_hsa012300.97977291
51Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.97644984
52Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.92917282
53MicroRNAs in cancer_Homo sapiens_hsa052060.91397995
54Oocyte meiosis_Homo sapiens_hsa041140.89820255
55T cell receptor signaling pathway_Homo sapiens_hsa046600.88399475
56Transcriptional misregulation in cancer_Homo sapiens_hsa052020.87588755
57Inositol phosphate metabolism_Homo sapiens_hsa005620.86568586
58Pentose and glucuronate interconversions_Homo sapiens_hsa000400.85279622
59Selenocompound metabolism_Homo sapiens_hsa004500.83304428
60Renal cell carcinoma_Homo sapiens_hsa052110.83208360
61Shigellosis_Homo sapiens_hsa051310.80118016
62Bacterial invasion of epithelial cells_Homo sapiens_hsa051000.79618408
63Carbon metabolism_Homo sapiens_hsa012000.78833307
64Non-homologous end-joining_Homo sapiens_hsa034500.77169814
65NF-kappa B signaling pathway_Homo sapiens_hsa040640.76251807
66Thyroid hormone signaling pathway_Homo sapiens_hsa049190.75469153
67Pathways in cancer_Homo sapiens_hsa052000.75438336
68Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.72917056
69Measles_Homo sapiens_hsa051620.72496939
70Phospholipase D signaling pathway_Homo sapiens_hsa040720.70190456
71Melanogenesis_Homo sapiens_hsa049160.70182004
72Regulation of actin cytoskeleton_Homo sapiens_hsa048100.69590187
73RNA polymerase_Homo sapiens_hsa030200.69235893
74Tight junction_Homo sapiens_hsa045300.67631416
75Proteasome_Homo sapiens_hsa030500.66558993
76AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049330.66517103
77Wnt signaling pathway_Homo sapiens_hsa043100.66402901
78Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046500.65174051
79Malaria_Homo sapiens_hsa051440.63905860
80Leishmaniasis_Homo sapiens_hsa051400.63813037
81Viral carcinogenesis_Homo sapiens_hsa052030.62809931
82Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.61317072
83Chemokine signaling pathway_Homo sapiens_hsa040620.61194354
84Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005320.60889853
85Chronic myeloid leukemia_Homo sapiens_hsa052200.60371517
86ErbB signaling pathway_Homo sapiens_hsa040120.59105149
87B cell receptor signaling pathway_Homo sapiens_hsa046620.58039156
88Dorso-ventral axis formation_Homo sapiens_hsa043200.57957762
89Citrate cycle (TCA cycle)_Homo sapiens_hsa000200.57735612
90Rap1 signaling pathway_Homo sapiens_hsa040150.56787492
91Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049610.56614727
92Other glycan degradation_Homo sapiens_hsa005110.55391472
93Tuberculosis_Homo sapiens_hsa051520.54884959
94Salmonella infection_Homo sapiens_hsa051320.54776267
95Bladder cancer_Homo sapiens_hsa052190.54616425
96Systemic lupus erythematosus_Homo sapiens_hsa053220.54539683
97Cytokine-cytokine receptor interaction_Homo sapiens_hsa040600.53937574
98Adherens junction_Homo sapiens_hsa045200.52992090
99Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.52604837
100Hematopoietic cell lineage_Homo sapiens_hsa046400.52476579
101Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010400.52250234
102Notch signaling pathway_Homo sapiens_hsa043300.51772083
103Cysteine and methionine metabolism_Homo sapiens_hsa002700.51286551
104Propanoate metabolism_Homo sapiens_hsa006400.50284040
105Hepatitis B_Homo sapiens_hsa051610.49979423
106Acute myeloid leukemia_Homo sapiens_hsa052210.48778181
107Pyrimidine metabolism_Homo sapiens_hsa002400.48675517
108Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.48572798
109TNF signaling pathway_Homo sapiens_hsa046680.48347044
110Ras signaling pathway_Homo sapiens_hsa040140.48323913
111AMPK signaling pathway_Homo sapiens_hsa041520.48225123
112HTLV-I infection_Homo sapiens_hsa051660.47747937
113Ether lipid metabolism_Homo sapiens_hsa005650.47727638
114Glycerophospholipid metabolism_Homo sapiens_hsa005640.47547936
115Glycosaminoglycan degradation_Homo sapiens_hsa005310.46883111
116Herpes simplex infection_Homo sapiens_hsa051680.46194416
117Phosphatidylinositol signaling system_Homo sapiens_hsa040700.45927858
118Choline metabolism in cancer_Homo sapiens_hsa052310.44741806
119FoxO signaling pathway_Homo sapiens_hsa040680.41763164
120PI3K-Akt signaling pathway_Homo sapiens_hsa041510.41145304
121Fc epsilon RI signaling pathway_Homo sapiens_hsa046640.40760418
122ECM-receptor interaction_Homo sapiens_hsa045120.40667968
123Proteoglycans in cancer_Homo sapiens_hsa052050.38782098
124Chemical carcinogenesis_Homo sapiens_hsa052040.38592872
125Pyruvate metabolism_Homo sapiens_hsa006200.37819850
126Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.37001032
127Focal adhesion_Homo sapiens_hsa045100.35125519
128Non-small cell lung cancer_Homo sapiens_hsa052230.34405933
129Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047500.34376342
130Colorectal cancer_Homo sapiens_hsa052100.33951640
131Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054120.33077611
132Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005340.32120602
133Ovarian steroidogenesis_Homo sapiens_hsa049130.32024917
134Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046660.30186577
135VEGF signaling pathway_Homo sapiens_hsa043700.30149655
136Butirosin and neomycin biosynthesis_Homo sapiens_hsa005240.29486857
137RIG-I-like receptor signaling pathway_Homo sapiens_hsa046220.28645925
138Alcoholism_Homo sapiens_hsa050340.28416447
139Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.28296684
140Cyanoamino acid metabolism_Homo sapiens_hsa004600.26092266
141Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.25448553
1422-Oxocarboxylic acid metabolism_Homo sapiens_hsa012100.25120882
143TGF-beta signaling pathway_Homo sapiens_hsa043500.24138323
144Small cell lung cancer_Homo sapiens_hsa052220.23828969
145African trypanosomiasis_Homo sapiens_hsa051430.22488986
146Apoptosis_Homo sapiens_hsa042100.21884661
147Long-term potentiation_Homo sapiens_hsa047200.20511252
148Lysine degradation_Homo sapiens_hsa003100.19994738
149Leukocyte transendothelial migration_Homo sapiens_hsa046700.19890475

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