SLC25A35

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: SLC25A35 belongs to the SLC25 family of mitochondrial carrier proteins (Haitina et al., 2006 [PubMed 16949250]). NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1DNA deamination (GO:0045006)6.56864015
2viral transcription (GO:0019083)6.05773090
3translational termination (GO:0006415)5.91649572
4SRP-dependent cotranslational protein targeting to membrane (GO:0006614)5.59908193
5ribosomal small subunit assembly (GO:0000028)5.58325386
6cotranslational protein targeting to membrane (GO:0006613)5.54700452
7protein targeting to ER (GO:0045047)5.49242832
8ribosomal small subunit biogenesis (GO:0042274)5.27437071
9establishment of protein localization to endoplasmic reticulum (GO:0072599)5.23284536
10protein localization to endoplasmic reticulum (GO:0070972)5.19810800
11translational elongation (GO:0006414)5.19053592
12L-methionine biosynthetic process from methylthioadenosine (GO:0019509)4.67266915
13mitochondrial electron transport, NADH to ubiquinone (GO:0006120)4.62588211
14ribosomal large subunit biogenesis (GO:0042273)4.61634064
15cytochrome complex assembly (GO:0017004)4.60696566
16cellular protein complex disassembly (GO:0043624)4.58454671
17maturation of SSU-rRNA (GO:0030490)4.57492824
18viral life cycle (GO:0019058)4.56792917
19translational initiation (GO:0006413)4.43729653
20GDP-mannose metabolic process (GO:0019673)4.37006204
21nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184)4.33066125
22respiratory electron transport chain (GO:0022904)4.29916976
23mitochondrial ATP synthesis coupled proton transport (GO:0042776)4.27341686
24electron transport chain (GO:0022900)4.24228377
25folic acid metabolic process (GO:0046655)4.21189586
26DNA strand renaturation (GO:0000733)4.19337564
27mitochondrial respiratory chain complex I assembly (GO:0032981)4.19291582
28NADH dehydrogenase complex assembly (GO:0010257)4.19291582
29mitochondrial respiratory chain complex I biogenesis (GO:0097031)4.19291582
30cullin deneddylation (GO:0010388)4.16142680
31translation (GO:0006412)4.15522451
32protein complex biogenesis (GO:0070271)4.02591242
33protein complex disassembly (GO:0043241)3.96737468
34mitochondrial respiratory chain complex assembly (GO:0033108)3.86453686
35ATP synthesis coupled proton transport (GO:0015986)3.84702452
36energy coupled proton transport, down electrochemical gradient (GO:0015985)3.84702452
37protein deneddylation (GO:0000338)3.81376283
38macromolecular complex disassembly (GO:0032984)3.76448121
39ubiquinone biosynthetic process (GO:0006744)3.72133417
40quinone biosynthetic process (GO:1901663)3.72133417
41protein targeting to membrane (GO:0006612)3.65440765
42ribonucleoprotein complex biogenesis (GO:0022613)3.58428985
43pyrimidine deoxyribonucleotide catabolic process (GO:0009223)3.56662927
44cellular component biogenesis (GO:0044085)3.52115525
45folic acid-containing compound biosynthetic process (GO:0009396)3.51574066
46mitotic cell cycle arrest (GO:0071850)3.50809350
47protein K6-linked ubiquitination (GO:0085020)3.50535105
48deoxyribonucleoside monophosphate metabolic process (GO:0009162)3.49840782
49regulation of respiratory burst (GO:0060263)3.46214301
50purine deoxyribonucleoside triphosphate metabolic process (GO:0009215)3.43731064
51branched-chain amino acid catabolic process (GO:0009083)3.43258289
52base-excision repair, AP site formation (GO:0006285)3.42525964
53termination of RNA polymerase III transcription (GO:0006386)3.42314818
54transcription elongation from RNA polymerase III promoter (GO:0006385)3.42314818
55meiotic chromosome segregation (GO:0045132)3.41838636
56L-methionine salvage (GO:0071267)3.40444494
57L-methionine biosynthetic process (GO:0071265)3.40444494
58amino acid salvage (GO:0043102)3.40444494
59inner mitochondrial membrane organization (GO:0007007)3.36695096
60estrogen biosynthetic process (GO:0006703)3.36368767
61proteasome assembly (GO:0043248)3.35258987
62negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436)3.34042264
63rRNA modification (GO:0000154)3.33234903
64tricarboxylic acid cycle (GO:0006099)3.31991218
65RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394)3.31936902
66tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388)3.31936902
67proline biosynthetic process (GO:0006561)3.25882447
68pseudouridine synthesis (GO:0001522)3.22164796
69NADH metabolic process (GO:0006734)3.22081652
70deoxyribonucleotide catabolic process (GO:0009264)3.21350111
71purine deoxyribonucleotide metabolic process (GO:0009151)3.20925110
72GTP biosynthetic process (GO:0006183)3.20618752
73metallo-sulfur cluster assembly (GO:0031163)3.19483457
74iron-sulfur cluster assembly (GO:0016226)3.19483457
75regulation of nuclear cell cycle DNA replication (GO:0033262)3.19398023
76oxidative phosphorylation (GO:0006119)3.18379552
77nuclear-transcribed mRNA catabolic process (GO:0000956)3.17473657
78guanosine-containing compound biosynthetic process (GO:1901070)3.16256679
79DNA replication checkpoint (GO:0000076)3.15494403
80axonemal dynein complex assembly (GO:0070286)3.14987310
81positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051437)3.14787988
82regulation of skeletal muscle contraction (GO:0014819)3.13364332
83respiratory chain complex IV assembly (GO:0008535)3.11123541
84cellular ketone body metabolic process (GO:0046950)3.09860639
85deoxyribonucleoside triphosphate metabolic process (GO:0009200)3.09849509
86purine deoxyribonucleotide catabolic process (GO:0009155)3.08573585
87biotin metabolic process (GO:0006768)3.08438443
88deoxyribose phosphate catabolic process (GO:0046386)3.05777180
892-deoxyribonucleotide metabolic process (GO:0009394)3.05618834
90ubiquinone metabolic process (GO:0006743)3.04025526
91fusion of sperm to egg plasma membrane (GO:0007342)3.03673640
92GPI anchor biosynthetic process (GO:0006506)3.03438845
93cilium or flagellum-dependent cell motility (GO:0001539)3.02484139
94negative regulation of ligase activity (GO:0051352)3.01568640
95negative regulation of ubiquitin-protein transferase activity (GO:0051444)3.01568640
96mRNA catabolic process (GO:0006402)3.00703056
97folic acid-containing compound metabolic process (GO:0006760)3.00508365
98branched-chain amino acid metabolic process (GO:0009081)2.99598197
99cardiolipin metabolic process (GO:0032048)2.98400674
100pyrimidine nucleotide catabolic process (GO:0006244)2.98174885
101rRNA processing (GO:0006364)2.97568287
102nucleoside diphosphate catabolic process (GO:0009134)2.96569578
103signal peptide processing (GO:0006465)2.96333778
104pyrimidine nucleoside triphosphate metabolic process (GO:0009147)2.95144048
105regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051439)2.94995200
106tetrahydrofolate metabolic process (GO:0046653)2.94981799
107regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:00450912.94879616
108negative regulation of cell aging (GO:0090344)2.93884930
109motile cilium assembly (GO:0044458)2.91885133
110deoxyribose phosphate metabolic process (GO:0019692)2.91685384
111nucleoside salvage (GO:0043174)2.91510887
112regulation of mitochondrial translation (GO:0070129)2.91332587
113regulation of cytokine production involved in inflammatory response (GO:1900015)2.89883304
114CTP metabolic process (GO:0046036)2.89825087
115CTP biosynthetic process (GO:0006241)2.89825087
116rRNA metabolic process (GO:0016072)2.89290070
117exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay 2.88243533
118pteridine-containing compound biosynthetic process (GO:0042559)2.87918796
119detection of light stimulus involved in sensory perception (GO:0050962)2.87061547
120detection of light stimulus involved in visual perception (GO:0050908)2.87061547
121transcription from mitochondrial promoter (GO:0006390)2.86881977
122pyrimidine deoxyribonucleotide metabolic process (GO:0009219)2.86780340
123purinergic nucleotide receptor signaling pathway (GO:0035590)2.86729169
124negative regulation of lipopolysaccharide-mediated signaling pathway (GO:0031665)2.85272225
125UTP metabolic process (GO:0046051)2.84854545
126DNA catabolic process, exonucleolytic (GO:0000738)2.84796835
127UTP biosynthetic process (GO:0006228)2.83879906
128protein K11-linked ubiquitination (GO:0070979)2.83016108
129mannosylation (GO:0097502)2.82265981
130dolichol-linked oligosaccharide biosynthetic process (GO:0006488)2.82084379
131rRNA methylation (GO:0031167)2.81378962
132telomere maintenance via semi-conservative replication (GO:0032201)2.81166498
133sperm-egg recognition (GO:0035036)2.81148828
134methionine biosynthetic process (GO:0009086)2.81084329
135tRNA modification (GO:0006400)2.80548001
136spliceosomal snRNP assembly (GO:0000387)2.78574173
137GMP metabolic process (GO:0046037)2.78501732
138G-protein coupled purinergic nucleotide receptor signaling pathway (GO:0035589)2.77846440
139anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process (GO:02.77203712
140RNA catabolic process (GO:0006401)2.76866832
141regulation of hydrogen peroxide metabolic process (GO:0010310)2.76753325
142cilium movement (GO:0003341)2.76701378
143nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291)2.75432171
144binding of sperm to zona pellucida (GO:0007339)2.74904172
145pentose metabolic process (GO:0019321)2.73688440
146valine metabolic process (GO:0006573)2.72222595
147protein targeting to mitochondrion (GO:0006626)2.71956744
148pteridine-containing compound metabolic process (GO:0042558)2.70244668
149establishment of integrated proviral latency (GO:0075713)2.70095969
150establishment of protein localization to membrane (GO:0090150)2.69590005
151cell wall macromolecule catabolic process (GO:0016998)2.69407994
152cell wall macromolecule metabolic process (GO:0044036)2.69407994
153purine ribonucleoside triphosphate biosynthetic process (GO:0009206)2.69139986
154protein targeting (GO:0006605)2.68922871
155epithelial cilium movement (GO:0003351)2.68886811
156signal transduction involved in mitotic cell cycle checkpoint (GO:0072413)2.68129515
157signal transduction involved in mitotic DNA integrity checkpoint (GO:1902403)2.68129515
158signal transduction involved in mitotic DNA damage checkpoint (GO:1902402)2.68129515
159digestion (GO:0007586)2.67438545
160ketone body metabolic process (GO:1902224)2.66921377
161positive regulation of ubiquitin-protein transferase activity (GO:0051443)2.66885768
162DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest (GO:002.66698281
163purine nucleotide salvage (GO:0032261)2.66616641
164tRNA processing (GO:0008033)2.66509730
165regulation of cellular amino acid metabolic process (GO:0006521)2.64991372
166nucleotide salvage (GO:0043173)2.64631969
167deoxyribonucleotide metabolic process (GO:0009262)2.62039750
168tRNA methylation (GO:0030488)2.61132880
169positive regulation of ligase activity (GO:0051351)2.60886156
170signal transduction involved in mitotic G1 DNA damage checkpoint (GO:0072431)2.58827500
171intracellular signal transduction involved in G1 DNA damage checkpoint (GO:1902400)2.58827500
172C-terminal protein lipidation (GO:0006501)2.58659571

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human4.44865424
2SOX9_22984422_ChIP-ChIP_TESTIS_Rat4.26450675
3MYC_18555785_ChIP-Seq_MESCs_Mouse4.19620585
4JARID1A_20064375_ChIP-Seq_MESCs_Mouse3.87739162
5NOTCH1_17114293_ChIP-ChIP_T-ALL_Human3.76631532
6GABP_17652178_ChIP-ChIP_JURKAT_Human3.68689347
7EST1_17652178_ChIP-ChIP_JURKAT_Human3.56644299
8ETS1_20019798_ChIP-Seq_JURKAT_Human3.43001548
9EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse3.23597492
10MYC_18358816_ChIP-ChIP_MESCs_Mouse3.18540469
11CREB1_15753290_ChIP-ChIP_HEK293T_Human3.17204312
12HCFC1_20581084_ChIP-Seq_MESCs_Mouse3.01280664
13CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human2.87482054
14MYC_19079543_ChIP-ChIP_MESCs_Mouse2.79711380
15CHD1_19587682_ChIP-ChIP_MESCs_Mouse2.68573028
16MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse2.68481441
17HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human2.59596694
18MYC_19030024_ChIP-ChIP_MESCs_Mouse2.54479412
19TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat2.49462706
20XRN2_22483619_ChIP-Seq_HELA_Human2.46507705
21VDR_23849224_ChIP-Seq_CD4+_Human2.44771056
22E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse2.40115021
23E2F1_18555785_ChIP-Seq_MESCs_Mouse2.34302155
24DCP1A_22483619_ChIP-Seq_HELA_Human2.34192363
25PPARG_19300518_ChIP-PET_3T3-L1_Mouse2.32754116
26SRF_21415370_ChIP-Seq_HL-1_Mouse2.29058667
27E2F7_22180533_ChIP-Seq_HELA_Human2.25672085
28ELF1_17652178_ChIP-ChIP_JURKAT_Human2.19444647
29* PDX1_19855005_ChIP-ChIP_MIN6_Mouse2.14152583
30VDR_21846776_ChIP-Seq_THP-1_Human2.11865044
31FOXP3_21729870_ChIP-Seq_TREG_Human2.11361684
32CEBPA_23403033_ChIP-Seq_LIVER_Mouse1.96266135
33GABP_19822575_ChIP-Seq_HepG2_Human1.94727202
34YY1_21170310_ChIP-Seq_MESCs_Mouse1.93580678
35THAP11_20581084_ChIP-Seq_MESCs_Mouse1.89162765
36IRF8_22096565_ChIP-ChIP_GC-B_Human1.88759724
37TTF2_22483619_ChIP-Seq_HELA_Human1.83442391
38SPI1_22096565_ChIP-ChIP_GC-B_Mouse1.80621499
39TAL1_20887958_ChIP-Seq_HPC-7_Mouse1.79058381
40FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse1.77063300
41CEBPB_24764292_ChIP-Seq_MC3T3_Mouse1.71644805
42TAF7L_23326641_ChIP-Seq_C3H10T1-2_Mouse1.69888781
43IRF8_22096565_ChIP-ChIP_GC-B_Mouse1.69863128
44NELFA_20434984_ChIP-Seq_ESCs_Mouse1.69849581
45FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human1.68780306
46* MAF_26560356_Chip-Seq_TH2_Human1.66481014
47FLI1_20887958_ChIP-Seq_HPC-7_Mouse1.64028702
48ZFP42_18358816_ChIP-ChIP_MESCs_Mouse1.63774214
49BCL6_27268052_Chip-Seq_Bcells_Human1.57680787
50IRF8_21731497_ChIP-ChIP_J774_Mouse1.56300189
51SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse1.54324458
52* CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human1.53429838
53ERG_20887958_ChIP-Seq_HPC-7_Mouse1.53193266
54HOXB4_20404135_ChIP-ChIP_EML_Mouse1.48997917
55P68_20966046_ChIP-Seq_HELA_Human1.47259769
56E2F4_17652178_ChIP-ChIP_JURKAT_Human1.46666142
57E2F1_20622854_ChIP-Seq_HELA_Human1.44538325
58ZFX_18555785_ChIP-Seq_MESCs_Mouse1.43560735
59AR_21909140_ChIP-Seq_LNCAP_Human1.42650335
60MAF_26560356_Chip-Seq_TH1_Human1.42032071
61STAT6_21828071_ChIP-Seq_BEAS2B_Human1.41294730
62CTCF_18555785_ChIP-Seq_MESCs_Mouse1.39790537
63MYC_18940864_ChIP-ChIP_HL60_Human1.39755405
64ELF1_20517297_ChIP-Seq_JURKAT_Human1.38852160
65BCOR_27268052_Chip-Seq_Bcells_Human1.37727900
66BCL3_23251550_ChIP-Seq_MUSCLE_Mouse1.36741774
67MYCN_18555785_ChIP-Seq_MESCs_Mouse1.36345389
68UTX_26944678_Chip-Seq_JUKART_Human1.35616485
69SPI1_23547873_ChIP-Seq_NB4_Human1.34356694
70PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse1.33316801
71PHF8_20622854_ChIP-Seq_HELA_Human1.32601587
72ZNF652_21678463_ChIP-ChIP_ZR75-1_Human1.26448102
73ASH2L_23239880_ChIP-Seq_MESCs_Mouse1.25413806
74RBPJ_21746931_ChIP-Seq_IB4-LCL_Human1.25068403
75TFEB_21752829_ChIP-Seq_HELA_Human1.24975320
76TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse1.21668480
77ELK1_19687146_ChIP-ChIP_HELA_Human1.20791914
78YY1_22570637_ChIP-Seq_MALME-3M_Human1.20472583
79VDR_24763502_ChIP-Seq_THP-1_Human1.20133828
80MYBL2_22936984_ChIP-ChIP_MESCs_Mouse1.19240974
81MYC_22102868_ChIP-Seq_BL_Human1.19232622
82* CCND1_20090754_ChIP-ChIP_RETINA_Mouse1.17942326
83SPI1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.15458905
84CHD7_19251738_ChIP-ChIP_MESCs_Mouse1.15005085
85RARB_24833708_ChIP-Seq_LIVER_Mouse1.14872764
86ESRRB_18555785_ChIP-Seq_MESCs_Mouse1.14464701
87POU5F1_18358816_ChIP-ChIP_MESCs_Mouse1.12995265
88MEIS1_20887958_ChIP-Seq_HPC-7_Mouse1.11817108
89PPARD_23208498_ChIP-Seq_MDA-MB-231_Human1.11611363
90TET1_21451524_ChIP-Seq_MESCs_Mouse1.10880434
91NANOG_18555785_ChIP-Seq_MESCs_Mouse1.10493531
92SFPI1_20887958_ChIP-Seq_HPC-7_Mouse1.10381174
93YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.09776220
94STAT4_19710469_ChIP-ChIP_TH1__Mouse1.08730955
95NOTCH1_21737748_ChIP-Seq_TLL_Human1.08477944
96DMRT1_21621532_ChIP-ChIP_FETAL_Ovary1.08156375
97POU5F1_18555785_ChIP-Seq_MESCs_Mouse1.07824606
98STAT1_20625510_ChIP-Seq_HELA_Human1.07043020
99ELK1_22589737_ChIP-Seq_MCF10A_Human1.06608806
100TBX5_21415370_ChIP-Seq_HL-1_Mouse1.05526483
101* MECOM_23826213_ChIP-Seq_KASUMI_Mouse1.05477930
102PU.1_20513432_ChIP-Seq_Bcells_Mouse1.03498515
103P300_27268052_Chip-Seq_Bcells_Human1.03352675
104EBNA2_21746931_ChIP-Seq_IB4-LCL_Human1.02856323
105RUNX1_20887958_ChIP-Seq_HPC-7_Mouse1.02454173
106* CTCF_20526341_ChIP-Seq_ESCs_Human1.01553912
107FOXM1_23109430_ChIP-Seq_U2OS_Human1.01053006
108CIITA_25753668_ChIP-Seq_RAJI_Human1.00195042
109HNF4A_19761587_ChIP-ChIP_CACO-2_Human0.99684348
110ERG_20517297_ChIP-Seq_VCAP_Human0.98803051
111STAT3_1855785_ChIP-Seq_MESCs_Mouse0.98094558
112E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human0.97099953
113SIN3A_21632747_ChIP-Seq_MESCs_Mouse0.95933946
114KDM5A_27292631_Chip-Seq_BREAST_Human0.95462761
115SMAD2/3_21741376_ChIP-Seq_ESCs_Human0.95010890
116E2F1_21310950_ChIP-Seq_MCF-7_Human0.94360251
117* E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human0.93538560
118CNOT3_19339689_ChIP-ChIP_MESCs_Mouse0.92605423
119DACH1_20351289_ChIP-Seq_MDA-MB-231_Human0.91691101
120* FOXP1_21924763_ChIP-Seq_HESCs_Human0.91596005
121GATA3_21867929_ChIP-Seq_CD8_Mouse0.88364684
122PADI4_21655091_ChIP-ChIP_MCF-7_Human0.84947454
123SRY_22984422_ChIP-ChIP_TESTIS_Rat0.83487260
124IRF1_19129219_ChIP-ChIP_H3396_Human0.82854874
125BMI1_19503595_ChIP-Seq_MEFsC_Mouse0.82795670
126NANOG_20526341_ChIP-Seq_ESCs_Human0.82490632
127* CREM_20920259_ChIP-Seq_GC1-SPG_Mouse0.82225811
128* SIN3B_21632747_ChIP-Seq_MESCs_Mouse0.82179187
129FLI1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.80403969
130MYCN_21190229_ChIP-Seq_SHEP-21N_Human0.79363156
131GFI1B_20887958_ChIP-Seq_HPC-7_Mouse0.79328000
132CEBPB_23403033_ChIP-Seq_LIVER_Mouse0.78150089
133* KLF4_18555785_ChIP-Seq_MESCs_Mouse0.76286363
134TCFCP2L1_18555785_ChIP-Seq_MESCs_Mouse0.76272113
135* CTCF_26484167_Chip-Seq_Bcells_Mouse0.75736807
136* STAT5_23275557_ChIP-Seq_MAMMARY-EPITHELIUM_Mouse0.71567283

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0009379_abnormal_foot_pigmentation3.71467975
2MP0003693_abnormal_embryo_hatching3.65345793
3MP0004043_abnormal_pH_regulation3.38506838
4MP0006036_abnormal_mitochondrial_physio3.05866643
5MP0008875_abnormal_xenobiotic_pharmacok2.78701542
6MP0005410_abnormal_fertilization2.67592516
7MP0004957_abnormal_blastocyst_morpholog2.54046776
8MP0005670_abnormal_white_adipose2.48605474
9MP0003806_abnormal_nucleotide_metabolis2.47627596
10MP0001835_abnormal_antigen_presentation2.47257665
11MP0001986_abnormal_taste_sensitivity2.42968818
12MP0003186_abnormal_redox_activity2.40774569
13MP0001666_abnormal_nutrient_absorption2.32101987
14MP0001873_stomach_inflammation2.31026316
15MP0001661_extended_life_span2.27736682
16MP0008004_abnormal_stomach_pH2.26756452
17MP0005171_absent_coat_pigmentation2.24605193
18MP0005671_abnormal_response_to2.18394782
19MP0006072_abnormal_retinal_apoptosis2.13347203
20MP0005220_abnormal_exocrine_pancreas2.03192112
21MP0001485_abnormal_pinna_reflex2.02817054
22MP0008789_abnormal_olfactory_epithelium1.99941345
23MP0003646_muscle_fatigue1.96572134
24MP0005058_abnormal_lysosome_morphology1.90938866
25MP0005499_abnormal_olfactory_system1.89394940
26MP0005394_taste/olfaction_phenotype1.89394940
27MP0008058_abnormal_DNA_repair1.88724859
28MP0002653_abnormal_ependyma_morphology1.87183475
29MP0003011_delayed_dark_adaptation1.86079272
30MP0005551_abnormal_eye_electrophysiolog1.82605296
31MP0000015_abnormal_ear_pigmentation1.81979103
32MP0003172_abnormal_lysosome_physiology1.76069104
33MP0002148_abnormal_hypersensitivity_rea1.73654962
34MP0006035_abnormal_mitochondrial_morpho1.70651239
35MP0005666_abnormal_adipose_tissue1.69699697
36MP0001929_abnormal_gametogenesis1.69682967
37MP0001984_abnormal_olfaction1.69399688
38MP0000685_abnormal_immune_system1.65833256
39MP0004147_increased_porphyrin_level1.62676467
40MP0003436_decreased_susceptibility_to1.62371224
41MP0001800_abnormal_humoral_immune1.62286502
42MP0001664_abnormal_digestion1.61377014
43MP0009333_abnormal_splenocyte_physiolog1.56696276
44MP0000569_abnormal_digit_pigmentation1.55924141
45MP0004264_abnormal_extraembryonic_tissu1.53718848
46MP0002277_abnormal_respiratory_mucosa1.53450378
47MP0002638_abnormal_pupillary_reflex1.53028846
48MP0002210_abnormal_sex_determination1.52152626
49MP0005000_abnormal_immune_tolerance1.47375735
50MP0000490_abnormal_crypts_of1.46588591
51MP0003763_abnormal_thymus_physiology1.46416012
52MP0004233_abnormal_muscle_weight1.45127764
53MP0000613_abnormal_salivary_gland1.43107453
54MP0001663_abnormal_digestive_system1.42748122
55MP0003698_abnormal_male_reproductive1.42174954
56MP0003718_maternal_effect1.42081765
57MP0002452_abnormal_antigen_presenting1.41129502
58MP0002723_abnormal_immune_serum1.40938411
59MP0010094_abnormal_chromosome_stability1.40919987
60MP0000566_synostosis1.39443876
61MP0005387_immune_system_phenotype1.37971183
62MP0001790_abnormal_immune_system1.37971183
63MP0001145_abnormal_male_reproductive1.36678345
64MP0002420_abnormal_adaptive_immunity1.36322043
65MP0002398_abnormal_bone_marrow1.34925182
66MP0009785_altered_susceptibility_to1.34828687
67MP0001919_abnormal_reproductive_system1.34567088
68MP0001819_abnormal_immune_cell1.34529751
69MP0010386_abnormal_urinary_bladder1.32985644
70MP0000358_abnormal_cell_content/1.32789955
71MP0002166_altered_tumor_susceptibility1.32597104
72MP0005381_digestive/alimentary_phenotyp1.32338760
73MP0004185_abnormal_adipocyte_glucose1.30006161
74MP0003136_yellow_coat_color1.29521611
75MP0001764_abnormal_homeostasis1.29117582
76MP0005025_abnormal_response_to1.27057616
77MP0009643_abnormal_urine_homeostasis1.25872905
78MP0008932_abnormal_embryonic_tissue1.25286388
79MP0001968_abnormal_touch/_nociception1.25018672
80MP0005083_abnormal_biliary_tract1.24123484
81MP0005332_abnormal_amino_acid1.23465770
82MP0005377_hearing/vestibular/ear_phenot1.23423477
83MP0003878_abnormal_ear_physiology1.23423477
84MP0006292_abnormal_olfactory_placode1.22973143
85MP0000653_abnormal_sex_gland1.22948413
86MP0002019_abnormal_tumor_incidence1.22488289
87MP0000470_abnormal_stomach_morphology1.21574920
88MP0003868_abnormal_feces_composition1.21410195
89MP0000689_abnormal_spleen_morphology1.21254519
90MP0005636_abnormal_mineral_homeostasis1.20422010
91MP0003950_abnormal_plasma_membrane1.19390846
92MP0005253_abnormal_eye_physiology1.19079080
93MP0003077_abnormal_cell_cycle1.18202243
94MP0000462_abnormal_digestive_system1.17747372
95MP0000678_abnormal_parathyroid_gland1.17040832
96MP0004381_abnormal_hair_follicle1.15199648
97MP0002429_abnormal_blood_cell1.15118340
98MP0005464_abnormal_platelet_physiology1.15055291
99MP0002971_abnormal_brown_adipose1.13291576
100MP0005389_reproductive_system_phenotype1.11650432
101MP0000716_abnormal_immune_system1.11642863
102MP0002722_abnormal_immune_system1.11428604
103MP0001765_abnormal_ion_homeostasis1.11236928
104MP0002419_abnormal_innate_immunity1.10781162
105MP0000703_abnormal_thymus_morphology1.09056992
106MP0001529_abnormal_vocalization1.08673061
107MP0004130_abnormal_muscle_cell1.08002692
108MP0008469_abnormal_protein_level1.07175256
109MP0003111_abnormal_nucleus_morphology1.06907242
110MP0001845_abnormal_inflammatory_respons1.06897709
111MP0006082_CNS_inflammation1.06432569
112MP0002693_abnormal_pancreas_physiology1.06224010
113MP0008057_abnormal_DNA_replication1.05630052
114MP0004215_abnormal_myocardial_fiber1.03723374
115MP0005375_adipose_tissue_phenotype1.02060631
116MP0001905_abnormal_dopamine_level1.01117771
117MP0008877_abnormal_DNA_methylation0.99928682
118MP0002405_respiratory_system_inflammati0.99841804
119MP0005266_abnormal_metabolism0.99199927
120MP0002970_abnormal_white_adipose0.98790140
121MP0002736_abnormal_nociception_after0.97931312
122MP0010155_abnormal_intestine_physiology0.97859916
123MP0001756_abnormal_urination0.97129290
124MP0005319_abnormal_enzyme/_coenzyme0.95622640
125MP0009764_decreased_sensitivity_to0.95015324
126MP0003866_abnormal_defecation0.93911750
127MP0005423_abnormal_somatic_nervous0.92005217
128MP0000538_abnormal_urinary_bladder0.91651196
129MP0000750_abnormal_muscle_regeneration0.90259388
130MP0008872_abnormal_physiological_respon0.89430444
131MP0005084_abnormal_gallbladder_morpholo0.89250398
132MP0005365_abnormal_bile_salt0.85686273
133MP0003959_abnormal_lean_body0.85310467
134MP0002254_reproductive_system_inflammat0.85207629
135MP0003724_increased_susceptibility_to0.84958655
136MP0002909_abnormal_adrenal_gland0.84782010
137MP0000367_abnormal_coat/_hair0.84145168
138MP0003786_premature_aging0.84057352
139MP0002160_abnormal_reproductive_system0.83950355
140MP0002006_tumorigenesis0.82548299
141MP0002234_abnormal_pharynx_morphology0.82505026
142MP0001944_abnormal_pancreas_morphology0.80115469
143MP0002132_abnormal_respiratory_system0.79503333
144MP0001853_heart_inflammation0.79102810
145MP0003137_abnormal_impulse_conducting0.77795827
146MP0005584_abnormal_enzyme/coenzyme_acti0.77649504
147MP0000003_abnormal_adipose_tissue0.76009371
148MP0002136_abnormal_kidney_physiology0.75558722
149MP0002161_abnormal_fertility/fecundity0.75248574
150MP0003195_calcinosis0.73952938
151MP0000313_abnormal_cell_death0.73539114
152MP0005075_abnormal_melanosome_morpholog0.73500368
153MP0002837_dystrophic_cardiac_calcinosis0.71898889
154MP0005379_endocrine/exocrine_gland_phen0.71669829
155MP0008007_abnormal_cellular_replicative0.70306898
156MP0003315_abnormal_perineum_morphology0.67376980
157MP0005330_cardiomyopathy0.65508918
158MP0000477_abnormal_intestine_morphology0.64724792
159MP0005174_abnormal_tail_pigmentation0.64582586

Predicted human phenotypes

RankGene SetZ-score
1Testicular atrophy (HP:0000029)5.21583029
2Hepatocellular necrosis (HP:0001404)4.70509610
3Hepatic necrosis (HP:0002605)4.61746576
4Increased muscle lipid content (HP:0009058)4.52779483
5Mitochondrial inheritance (HP:0001427)4.48333562
6Acute necrotizing encephalopathy (HP:0006965)4.38856665
7Abnormal mitochondria in muscle tissue (HP:0008316)4.37152909
8Abnormality of cells of the erythroid lineage (HP:0012130)4.21584467
9Increased intramyocellular lipid droplets (HP:0012240)4.20336343
10Abnormal number of erythroid precursors (HP:0012131)4.10941847
11Acute encephalopathy (HP:0006846)4.08509454
12Decreased activity of mitochondrial respiratory chain (HP:0008972)4.08339278
13Abnormal activity of mitochondrial respiratory chain (HP:0011922)4.08339278
14Increased CSF lactate (HP:0002490)4.06303441
15Reticulocytopenia (HP:0001896)3.72225091
16Lipid accumulation in hepatocytes (HP:0006561)3.65119704
17Attenuation of retinal blood vessels (HP:0007843)3.56226379
18Lactic acidosis (HP:0003128)3.47030925
19Increased serum lactate (HP:0002151)3.44963847
20Progressive macrocephaly (HP:0004481)3.42237960
21Macrocytic anemia (HP:0001972)3.41606418
22Dyschromatopsia (HP:0007641)3.41524826
23Increased hepatocellular lipid droplets (HP:0006565)3.40578936
24Renal Fanconi syndrome (HP:0001994)3.24846998
25Mesangial abnormality (HP:0001966)3.24538285
26Exercise intolerance (HP:0003546)3.23258153
27Abnormality of pyruvate family amino acid metabolism (HP:0010915)3.15332860
28Abnormality of alanine metabolism (HP:0010916)3.15332860
29Hyperalaninemia (HP:0003348)3.15332860
30Respiratory insufficiency due to defective ciliary clearance (HP:0200073)3.11937198
31Abnormal ciliary motility (HP:0012262)3.11906234
32Hyperglycinuria (HP:0003108)3.10079313
33Abnormality of glycolysis (HP:0004366)3.07271249
34Increased serum pyruvate (HP:0003542)3.07271249
35Hypoalbuminemia (HP:0003073)3.04708198
36Abnormal albumin level (HP:0012116)3.04708198
37Respiratory failure (HP:0002878)3.01350408
38Abnormal respiratory motile cilium physiology (HP:0012261)2.99660805
39Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688)2.99489371
40Decreased electroretinogram (ERG) amplitude (HP:0000654)2.94465950
41Abnormal hemoglobin (HP:0011902)2.89614364
42Muscle abnormality related to mitochondrial dysfunction (HP:0003800)2.86463483
43Absent/shortened dynein arms (HP:0200106)2.81915657
44Dynein arm defect of respiratory motile cilia (HP:0012255)2.81915657
45Abnormal respiratory motile cilium morphology (HP:0005938)2.81781754
46Abnormal respiratory epithelium morphology (HP:0012253)2.81781754
47Oral leukoplakia (HP:0002745)2.76247817
48Pallor (HP:0000980)2.74958716
49Dicarboxylic aciduria (HP:0003215)2.69127562
50Abnormality of dicarboxylic acid metabolism (HP:0010995)2.69127562
51Chronic bronchitis (HP:0004469)2.68634727
52Abnormality of renal resorption (HP:0011038)2.64563266
53Rectovaginal fistula (HP:0000143)2.64402717
54Rectal fistula (HP:0100590)2.64402717
55Exertional dyspnea (HP:0002875)2.62625635
56Optic disc pallor (HP:0000543)2.59398613
57Ragged-red muscle fibers (HP:0003200)2.58691335
58Cerebral edema (HP:0002181)2.57543616
59Hypoplasia of the capital femoral epiphysis (HP:0003090)2.57453849
60Facial diplegia (HP:0001349)2.57237686
61Methylmalonic aciduria (HP:0012120)2.50993506
62Absent rod-and cone-mediated responses on ERG (HP:0007688)2.49043330
633-Methylglutaconic aciduria (HP:0003535)2.48040765
64Abnormality of fatty-acid metabolism (HP:0004359)2.47691974
65Premature graying of hair (HP:0002216)2.47150841
66Myoglobinuria (HP:0002913)2.44658672
67Congenital stationary night blindness (HP:0007642)2.44293418
68Aplasia/Hypoplasia of the sacrum (HP:0008517)2.42711830
69Hypoplasia of the uterus (HP:0000013)2.39535426
70Petechiae (HP:0000967)2.38728483
71Cerebral hypomyelination (HP:0006808)2.38572773
72Squamous cell carcinoma (HP:0002860)2.37216303
73Abnormality of serine family amino acid metabolism (HP:0010894)2.34399388
74Abnormality of glycine metabolism (HP:0010895)2.34399388
75CNS demyelination (HP:0007305)2.34041814
76Rhabdomyolysis (HP:0003201)2.32124519
77Intestinal fistula (HP:0100819)2.31128106
78Choroideremia (HP:0001139)2.30880615
79Poikiloderma (HP:0001029)2.28450847
80Respiratory difficulties (HP:0002880)2.27273630
81Metabolic alkalosis (HP:0200114)2.26042247
82Lethargy (HP:0001254)2.24570095
83Vaginal fistula (HP:0004320)2.23770664
84Delayed CNS myelination (HP:0002188)2.20567029
85Emotional lability (HP:0000712)2.18208891
86Bony spicule pigmentary retinopathy (HP:0007737)2.17106298
87Proximal tubulopathy (HP:0000114)2.16119147
88Thyroid-stimulating hormone excess (HP:0002925)2.14843414
89Aplastic anemia (HP:0001915)2.13943748
90Abnormal rod and cone electroretinograms (HP:0008323)2.13301599
91Type I transferrin isoform profile (HP:0003642)2.11961493
92Abnormality of urine glucose concentration (HP:0011016)2.11808649
93Glycosuria (HP:0003076)2.11808649
94Hyperactive renin-angiotensin system (HP:0000841)2.11616492
95Leukodystrophy (HP:0002415)2.10752422
96Aplasia/hypoplasia of the uterus (HP:0008684)2.10615133
97Progressive microcephaly (HP:0000253)2.09405472
98Pancytopenia (HP:0001876)2.08011765
99Rhinitis (HP:0012384)2.07764694
100Aplasia/Hypoplasia of the capital femoral epiphysis (HP:0005003)2.05484346
101Absent epiphyses (HP:0010577)2.05484346
102Tubulointerstitial nephritis (HP:0001970)2.05359837
103Abnormality of placental membranes (HP:0011409)2.04758003
104Amniotic constriction ring (HP:0009775)2.04758003
105Prolonged partial thromboplastin time (HP:0003645)2.04496250
106Microvesicular hepatic steatosis (HP:0001414)2.03331942
107Abnormal trabecular bone morphology (HP:0100671)2.01103214
108Bone marrow hypocellularity (HP:0005528)2.00950768
109Microretrognathia (HP:0000308)2.00831818
110Decreased central vision (HP:0007663)2.00225472
111Nasal polyposis (HP:0100582)1.99846444
112Renal salt wasting (HP:0000127)1.98653884
113Progressive muscle weakness (HP:0003323)1.95782019
114Absent thumb (HP:0009777)1.95300569
115Panhypogammaglobulinemia (HP:0003139)1.94759271
116Chronic mucocutaneous candidiasis (HP:0002728)1.92585003
117Recurrent cutaneous fungal infections (HP:0011370)1.92585003
118Abnormal isoelectric focusing of serum transferrin (HP:0003160)1.91858889
119Abnormal protein N-linked glycosylation (HP:0012347)1.91858889
120Abnormal protein glycosylation (HP:0012346)1.91858889
121Abnormal glycosylation (HP:0012345)1.91858889
122Generalized aminoaciduria (HP:0002909)1.91623724
123Severe visual impairment (HP:0001141)1.91452780
124Premature ovarian failure (HP:0008209)1.87963270
125Rib fusion (HP:0000902)1.87876858
126Breast hypoplasia (HP:0003187)1.87853844
127Maternal diabetes (HP:0009800)1.85931080
128Palpitations (HP:0001962)1.85674056
129Bronchiectasis (HP:0002110)1.85268749
130Carpal bone hypoplasia (HP:0001498)1.85244713
131Epiphyseal stippling (HP:0010655)1.83697848
132Hypomagnesemia (HP:0002917)1.83520182
133Patellar aplasia (HP:0006443)1.83288946
134Joint hemorrhage (HP:0005261)1.83093198
135Hyperphosphaturia (HP:0003109)1.82826717
136Rough bone trabeculation (HP:0100670)1.82517231
137Abnormality of long-chain fatty-acid metabolism (HP:0010964)1.82486427
138Abnormality of renin-angiotensin system (HP:0000847)1.80694728
139Onycholysis (HP:0001806)1.80334749
140Birth length less than 3rd percentile (HP:0003561)1.79815826
141Elevated erythrocyte sedimentation rate (HP:0003565)1.78814640
142Type I diabetes mellitus (HP:0100651)1.78493086
143Hyperaldosteronism (HP:0000859)1.78284216
144Progressive neurologic deterioration (HP:0002344)1.77864636
145Pili torti (HP:0003777)1.76706393
146Acute hepatic failure (HP:0006554)1.76142550
147Delayed epiphyseal ossification (HP:0002663)1.75463893
148Pustule (HP:0200039)1.75380372
149Abnormality of mucopolysaccharide metabolism (HP:0011020)1.75301034
150Abnormality of polysaccharide metabolism (HP:0011012)1.75301034
151Abnormality of glycosaminoglycan metabolism (HP:0004371)1.75301034
152Cheilitis (HP:0100825)1.74089184
153Aplasia/Hypoplasia of the patella (HP:0006498)1.73242830

Predicted kinase interactions (KEA)

RankGene SetZ-score
1BCKDK4.76092433
2PDK43.72984392
3PDK33.72984392
4ZAK3.68319361
5NME23.41096124
6NME13.09919296
7TLK13.04475409
8EIF2AK13.02035113
9PDK23.00389763
10BUB12.90615273
11VRK22.75270414
12STK162.63741578
13PBK2.55596233
14TIE12.43849536
15STK392.40542483
16MAP4K22.37797830
17WEE12.23411365
18VRK12.11069754
19IRAK32.10545992
20EIF2AK31.99629447
21WNK41.96343901
22MAP4K11.83351955
23CDK191.77479923
24MUSK1.76092702
25LMTK21.74679900
26TESK21.66399114
27OXSR11.65181435
28BLK1.64144260
29PLK41.60095626
30TNK21.52887508
31GRK11.46141683
32GRK61.40847900
33MST41.38515507
34TTK1.38279899
35RIPK41.32708481
36TNIK1.31263459
37ADRBK21.30736636
38IKBKB1.27654142
39TXK1.26999583
40TAOK31.20845971
41TGFBR11.14155048
42TEC1.14077031
43TBK11.07777271
44MAP2K21.05493869
45IRAK11.03692913
46RPS6KB21.02864325
47SRPK11.00491918
48MYLK0.95740636
49STK38L0.95087935
50SYK0.93029216
51MARK30.92133995
52BMPR20.91148906
53ACVR1B0.90191648
54DAPK10.87251827
55TSSK60.86775738
56EEF2K0.84584157
57SIK30.84190696
58BRSK20.83003732
59PLK10.79374336
60TRPM70.78298744
61FES0.77962031
62BTK0.77401963
63MAPKAPK30.76342776
64DYRK30.75670466
65MAP2K30.74845575
66PLK30.74587756
67MAPKAPK50.74107832
68KDR0.73930762
69AURKB0.73584758
70PRKAA20.72958178
71MKNK20.72055532
72MAPK110.70031756
73AURKA0.69299137
74KIT0.69245190
75LYN0.69193700
76LRRK20.68827863
77MAPK150.67947767
78TESK10.66884113
79IRAK20.65571565
80CDC70.65495640
81TYK20.65488977
82IRAK40.65363437
83CDK70.65273619
84PRKD30.64123726
85NEK60.61777828
86TAF10.60824855
87PRKCI0.60473378
88ERN10.60182131
89MAP3K80.57531854
90ILK0.57512315
91SMG10.57310096
92PINK10.56857893
93PIM20.56303316
94ITK0.55497553
95TRIM280.55095471
96IKBKE0.53794044
97MAP3K140.53020687
98EIF2AK20.52773433
99CCNB10.50789222
100STK100.50766049
101CDK40.49686680
102CSNK2A20.49554388
103CDK80.48884735
104FLT30.48720029
105RPS6KA40.47918373
106BRAF0.47354107
107PNCK0.47167957
108CSF1R0.46623093
109CSNK2A10.46370846
110PAK40.46364073
111CAMK2D0.45644308
112NEK90.45236055
113INSRR0.42499179
114GRK50.41159540
115CHEK20.40571515
116ADRBK10.40554282
117MAP2K60.39986430
118CAMK10.39683766
119CSNK1G10.37858721
120ATM0.37000750
121RPS6KA50.36948971
122FRK0.35983331
123ATR0.34961529
124BMPR1B0.34846057
125PAK10.34768930
126PIK3CA0.34761165
127PHKG10.34431052
128PHKG20.34431052
129CSNK1G30.34428033
130CAMK1D0.33880143
131PRKCQ0.33734291
132PASK0.32385896
133NEK10.32164600
134GRK70.31655998
135MAPKAPK20.31649741
136ZAP700.31567566
137MAP3K130.30956666
138MAP3K110.30110423
139LCK0.30091513
140MKNK10.29469645
141CAMK2B0.25549420
142NUAK10.23976552
143NEK20.23854600
144CDK90.23139172
145WNK30.22796578
146CAMK2G0.22322492
147NLK0.21497084

Predicted pathways (KEGG)

RankGene SetZ-score
1Ribosome_Homo sapiens_hsa030104.73526425
2Oxidative phosphorylation_Homo sapiens_hsa001903.34265620
3Protein export_Homo sapiens_hsa030603.14680494
4Citrate cycle (TCA cycle)_Homo sapiens_hsa000202.94957990
5Parkinsons disease_Homo sapiens_hsa050122.94652440
6RNA polymerase_Homo sapiens_hsa030202.76079545
7Propanoate metabolism_Homo sapiens_hsa006402.72376755
8Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006042.42283160
9Huntingtons disease_Homo sapiens_hsa050162.38501316
10DNA replication_Homo sapiens_hsa030302.37873900
11Proteasome_Homo sapiens_hsa030502.22193605
12Mismatch repair_Homo sapiens_hsa034302.20110041
13Valine, leucine and isoleucine degradation_Homo sapiens_hsa002802.07580627
14Pyruvate metabolism_Homo sapiens_hsa006202.06245924
15Alzheimers disease_Homo sapiens_hsa050102.04648365
16Glycosaminoglycan degradation_Homo sapiens_hsa005312.03014398
17Pyrimidine metabolism_Homo sapiens_hsa002401.93453077
18Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049321.91185474
19Homologous recombination_Homo sapiens_hsa034401.77608774
20Primary immunodeficiency_Homo sapiens_hsa053401.72270683
21Sulfur metabolism_Homo sapiens_hsa009201.69707564
22Phototransduction_Homo sapiens_hsa047441.66109469
23Fatty acid degradation_Homo sapiens_hsa000711.62320826
24Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030081.62309655
25Pentose phosphate pathway_Homo sapiens_hsa000301.56784483
26Asthma_Homo sapiens_hsa053101.56601754
27Sulfur relay system_Homo sapiens_hsa041221.56446831
28Folate biosynthesis_Homo sapiens_hsa007901.55272967
29Carbon metabolism_Homo sapiens_hsa012001.51655080
30Pancreatic secretion_Homo sapiens_hsa049721.51363207
31Spliceosome_Homo sapiens_hsa030401.49655535
32Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005631.46741713
33Purine metabolism_Homo sapiens_hsa002301.41151104
34Intestinal immune network for IgA production_Homo sapiens_hsa046721.38589711
35Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006031.36468745
36Basal transcription factors_Homo sapiens_hsa030221.33805802
37Fatty acid elongation_Homo sapiens_hsa000621.32583001
38Allograft rejection_Homo sapiens_hsa053301.30918461
39Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009701.30423594
40Base excision repair_Homo sapiens_hsa034101.30406810
41Glutathione metabolism_Homo sapiens_hsa004801.29204145
42Graft-versus-host disease_Homo sapiens_hsa053321.26563102
43Fructose and mannose metabolism_Homo sapiens_hsa000511.26249620
44Nucleotide excision repair_Homo sapiens_hsa034201.24749261
45Type I diabetes mellitus_Homo sapiens_hsa049401.23324111
46Fatty acid metabolism_Homo sapiens_hsa012121.20602344
47Glycolysis / Gluconeogenesis_Homo sapiens_hsa000101.17231582
482-Oxocarboxylic acid metabolism_Homo sapiens_hsa012101.15395233
49Fat digestion and absorption_Homo sapiens_hsa049751.14359103
50Cysteine and methionine metabolism_Homo sapiens_hsa002701.13988872
51SNARE interactions in vesicular transport_Homo sapiens_hsa041301.13666073
52RNA degradation_Homo sapiens_hsa030181.11173147
53RNA transport_Homo sapiens_hsa030131.08614087
54Glycerolipid metabolism_Homo sapiens_hsa005611.07771846
55Linoleic acid metabolism_Homo sapiens_hsa005911.07117068
56Cyanoamino acid metabolism_Homo sapiens_hsa004601.04071209
57Fanconi anemia pathway_Homo sapiens_hsa034601.03929607
58alpha-Linolenic acid metabolism_Homo sapiens_hsa005921.03508996
59Cardiac muscle contraction_Homo sapiens_hsa042601.02142825
60Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006301.01246852
61Lysosome_Homo sapiens_hsa041421.01234219
62Arachidonic acid metabolism_Homo sapiens_hsa005901.00393143
63Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.98714994
64Synthesis and degradation of ketone bodies_Homo sapiens_hsa000720.98673304
65Metabolic pathways_Homo sapiens_hsa011000.97310713
66Non-homologous end-joining_Homo sapiens_hsa034500.95962190
67Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001300.94377038
68Fatty acid biosynthesis_Homo sapiens_hsa000610.88479913
69Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.88316844
70Hematopoietic cell lineage_Homo sapiens_hsa046400.88104114
71Biosynthesis of amino acids_Homo sapiens_hsa012300.83757203
72Nitrogen metabolism_Homo sapiens_hsa009100.82774680
73Inflammatory bowel disease (IBD)_Homo sapiens_hsa053210.80091123
74Regulation of autophagy_Homo sapiens_hsa041400.79913073
75Protein digestion and absorption_Homo sapiens_hsa049740.78414522
76Cytosolic DNA-sensing pathway_Homo sapiens_hsa046230.78184701
77Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.76779005
78N-Glycan biosynthesis_Homo sapiens_hsa005100.75513906
79Maturity onset diabetes of the young_Homo sapiens_hsa049500.75510473
80Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.74548267
81Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.73330060
82One carbon pool by folate_Homo sapiens_hsa006700.72684345
83Butanoate metabolism_Homo sapiens_hsa006500.71932220
84Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.70836397
85Other glycan degradation_Homo sapiens_hsa005110.69415185
86Rheumatoid arthritis_Homo sapiens_hsa053230.68990975
87Sphingolipid metabolism_Homo sapiens_hsa006000.60467579
88Vitamin digestion and absorption_Homo sapiens_hsa049770.57336887
89Arginine and proline metabolism_Homo sapiens_hsa003300.56146103
90Peroxisome_Homo sapiens_hsa041460.55574303
91NOD-like receptor signaling pathway_Homo sapiens_hsa046210.55453277
92Herpes simplex infection_Homo sapiens_hsa051680.54509078
93Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.53527154
94Drug metabolism - other enzymes_Homo sapiens_hsa009830.53509603
95Pentose and glucuronate interconversions_Homo sapiens_hsa000400.49351621
96Drug metabolism - cytochrome P450_Homo sapiens_hsa009820.48898880
97RIG-I-like receptor signaling pathway_Homo sapiens_hsa046220.45358926
98beta-Alanine metabolism_Homo sapiens_hsa004100.45024928
99Leishmaniasis_Homo sapiens_hsa051400.43411313
100Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.42380272
101Shigellosis_Homo sapiens_hsa051310.41919781
102PPAR signaling pathway_Homo sapiens_hsa033200.41622211
103Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.41461442
104Cell cycle_Homo sapiens_hsa041100.40780280
105Vitamin B6 metabolism_Homo sapiens_hsa007500.40704717
106Vibrio cholerae infection_Homo sapiens_hsa051100.40125876
107Staphylococcus aureus infection_Homo sapiens_hsa051500.40020490
108Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.39631803
109Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.39082035
110Ether lipid metabolism_Homo sapiens_hsa005650.37589751
111Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.37495168
112Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.36882670
113Tuberculosis_Homo sapiens_hsa051520.36034318
114Galactose metabolism_Homo sapiens_hsa000520.35974980
115NF-kappa B signaling pathway_Homo sapiens_hsa040640.34133947
116Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049640.32053448
117Tryptophan metabolism_Homo sapiens_hsa003800.31130312
118Selenocompound metabolism_Homo sapiens_hsa004500.30008923
119Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.29483000
120Renin-angiotensin system_Homo sapiens_hsa046140.28807910
121Lysine degradation_Homo sapiens_hsa003100.27199545
122Epstein-Barr virus infection_Homo sapiens_hsa051690.26254568
123Glycerophospholipid metabolism_Homo sapiens_hsa005640.22698292
124Chemical carcinogenesis_Homo sapiens_hsa052040.22291771
125Autoimmune thyroid disease_Homo sapiens_hsa053200.19946275
126mRNA surveillance pathway_Homo sapiens_hsa030150.19827297
127p53 signaling pathway_Homo sapiens_hsa041150.19397290
128Mineral absorption_Homo sapiens_hsa049780.18221214
129Antigen processing and presentation_Homo sapiens_hsa046120.17023949
130Collecting duct acid secretion_Homo sapiens_hsa049660.16984994
131Thyroid hormone synthesis_Homo sapiens_hsa049180.14206888

Most similar genes based on co-expression Upload to Enrichr

Tissue Expression Export image »

Cell Line Expression Export image »