SLC25A18

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1L-amino acid import (GO:0043092)5.64165397
2cellular potassium ion homeostasis (GO:0030007)5.53252635
3L-phenylalanine catabolic process (GO:0006559)5.51454977
4erythrose 4-phosphate/phosphoenolpyruvate family amino acid catabolic process (GO:1902222)5.51454977
5amino acid import (GO:0043090)5.37085298
6sodium ion export (GO:0071436)5.35925412
7gamma-aminobutyric acid transport (GO:0015812)5.24363206
8cell communication by electrical coupling (GO:0010644)5.04174925
9exogenous drug catabolic process (GO:0042738)4.98747425
10complement activation, alternative pathway (GO:0006957)4.93798293
11L-phenylalanine metabolic process (GO:0006558)4.90508684
12erythrose 4-phosphate/phosphoenolpyruvate family amino acid metabolic process (GO:1902221)4.90508684
13locomotory exploration behavior (GO:0035641)4.88415204
14drug catabolic process (GO:0042737)4.76055271
15negative regulation of astrocyte differentiation (GO:0048712)4.70952850
16alanine transport (GO:0032328)4.69466477
17neurotransmitter-gated ion channel clustering (GO:0072578)4.64062510
18glyoxylate metabolic process (GO:0046487)4.63689030
19C4-dicarboxylate transport (GO:0015740)4.58718291
20regulation of short-term neuronal synaptic plasticity (GO:0048172)4.55316217
21omega-hydroxylase P450 pathway (GO:0097267)4.52959717
22regulation of atrial cardiac muscle cell membrane depolarization (GO:0060371)4.48952867
23regulation of protein activation cascade (GO:2000257)4.47273037
24epoxygenase P450 pathway (GO:0019373)4.46187379
25neurotransmitter uptake (GO:0001504)4.35033056
26negative regulation of amyloid precursor protein catabolic process (GO:1902992)4.34021422
27regulation of fibrinolysis (GO:0051917)4.28180205
28regulation of complement activation (GO:0030449)4.20431969
29cellular sodium ion homeostasis (GO:0006883)4.15807432
30membrane depolarization during cardiac muscle cell action potential (GO:0086012)4.11434791
31potassium ion import (GO:0010107)4.10778372
32negative regulation of fibrinolysis (GO:0051918)4.08505370
33axon ensheathment in central nervous system (GO:0032291)4.04222646
34central nervous system myelination (GO:0022010)4.04222646
35triglyceride-rich lipoprotein particle remodeling (GO:0034370)3.96927800
36response to auditory stimulus (GO:0010996)3.92149154
37synaptic vesicle maturation (GO:0016188)3.89834575
38negative regulation of sodium ion transport (GO:0010766)3.87202882
39cell communication by electrical coupling involved in cardiac conduction (GO:0086064)3.87098169
40regulation of ventricular cardiac muscle cell membrane repolarization (GO:0060307)3.86406584
41synaptic vesicle exocytosis (GO:0016079)3.81212216
42negative regulation of sterol transport (GO:0032372)3.77902220
43negative regulation of cholesterol transport (GO:0032375)3.77902220
44neuron cell-cell adhesion (GO:0007158)3.77646697
45ethanol oxidation (GO:0006069)3.76772224
46regulation of beta-amyloid formation (GO:1902003)3.76172808
47glutamate secretion (GO:0014047)3.75221085
48low-density lipoprotein particle remodeling (GO:0034374)3.74672621
49potassium ion homeostasis (GO:0055075)3.74072878
50glutamate metabolic process (GO:0006536)3.73897321
51serine family amino acid catabolic process (GO:0009071)3.73774385
52positive regulation of excitatory postsynaptic membrane potential (GO:2000463)3.72638087
53regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor act3.71155969
54vocalization behavior (GO:0071625)3.70623933
55atrial cardiac muscle cell action potential (GO:0086014)3.69101161
56proline transport (GO:0015824)3.59213790
57protein carboxylation (GO:0018214)3.58315992
58peptidyl-glutamic acid carboxylation (GO:0017187)3.58315992
59positive regulation of synaptic transmission, glutamatergic (GO:0051968)3.57889366
60negative regulation of synaptic transmission, GABAergic (GO:0032229)3.54477704
61adenine nucleotide transport (GO:0051503)3.54336170
62aromatic amino acid family catabolic process (GO:0009074)3.53454968
63ionotropic glutamate receptor signaling pathway (GO:0035235)3.50765951
64neurotransmitter secretion (GO:0007269)3.50482707
65regulation of respiratory gaseous exchange by neurological system process (GO:0002087)3.47146804
66regulation of neuronal synaptic plasticity (GO:0048168)3.46913915
67positive regulation of potassium ion transmembrane transporter activity (GO:1901018)3.44254360
68auditory behavior (GO:0031223)3.42711116
69chondroitin sulfate catabolic process (GO:0030207)3.42270205
70regulation of glutamate receptor signaling pathway (GO:1900449)3.39802453
71layer formation in cerebral cortex (GO:0021819)3.39556149
72regulation of astrocyte differentiation (GO:0048710)3.39147651
73cellular response to cholesterol (GO:0071397)3.37206999
74dicarboxylic acid biosynthetic process (GO:0043650)3.35406264
75drug metabolic process (GO:0017144)3.33759944
76urea metabolic process (GO:0019627)3.33274761
77glutamate receptor signaling pathway (GO:0007215)3.30953110
78bile acid biosynthetic process (GO:0006699)3.30800297
79regulation of cholesterol esterification (GO:0010872)3.30707650
80fibrinolysis (GO:0042730)3.30368674
81exploration behavior (GO:0035640)3.29568500
82acidic amino acid transport (GO:0015800)3.28223908
83positive regulation of calcium ion-dependent exocytosis (GO:0045956)3.27896485
84blood coagulation, intrinsic pathway (GO:0007597)3.27071202
85L-serine transport (GO:0015825)3.25998054
86neuronal action potential propagation (GO:0019227)3.24176174
87regulation of long-term neuronal synaptic plasticity (GO:0048169)3.23596205
88regulation of synaptic vesicle exocytosis (GO:2000300)3.21286422
89postsynaptic membrane organization (GO:0001941)3.20545911
90positive regulation of cellular amide metabolic process (GO:0034250)3.20023693
91phospholipid efflux (GO:0033700)3.18987520
92protein localization to synapse (GO:0035418)3.16173785
93synaptic transmission, glutamatergic (GO:0035249)3.15235749
94reverse cholesterol transport (GO:0043691)3.14261683
95regulation of amyloid precursor protein catabolic process (GO:1902991)3.13934712
96presynaptic membrane organization (GO:0097090)3.12523734
97nitrogen cycle metabolic process (GO:0071941)3.12479865
98long-term synaptic potentiation (GO:0060291)3.11100269
99regulation of synapse structural plasticity (GO:0051823)3.09642133
100long-term memory (GO:0007616)3.09225048
101cerebellar granule cell differentiation (GO:0021707)3.07642708
102neurotransmitter transport (GO:0006836)3.07301468
103oxidative demethylation (GO:0070989)3.06465903
104neuronal ion channel clustering (GO:0045161)3.05031885
105regulation of triglyceride catabolic process (GO:0010896)3.03613842
106regulation of synaptic transmission, glutamatergic (GO:0051966)3.03585198
107protein-lipid complex remodeling (GO:0034368)3.00885386
108macromolecular complex remodeling (GO:0034367)3.00885386
109plasma lipoprotein particle remodeling (GO:0034369)3.00885386
110transmission of nerve impulse (GO:0019226)2.99259939
111bile acid metabolic process (GO:0008206)2.98513888
112negative regulation of smoothened signaling pathway (GO:0045879)2.98359800
113ovulation cycle (GO:0042698)2.97866803
114purine nucleotide transport (GO:0015865)2.97590013
115protein activation cascade (GO:0072376)2.96648209
116regulation of neurotransmitter levels (GO:0001505)2.96513487
117negative regulation of glial cell differentiation (GO:0045686)2.96243147
118high-density lipoprotein particle remodeling (GO:0034375)2.95321838
119cellular glucuronidation (GO:0052695)2.94927412
120G-protein coupled glutamate receptor signaling pathway (GO:0007216)2.93590349
121triglyceride homeostasis (GO:0070328)2.92107251
122acylglycerol homeostasis (GO:0055090)2.92107251
123regulation of synaptic vesicle transport (GO:1902803)2.91269738
124L-glutamate transport (GO:0015813)2.90702950
125regulation of N-methyl-D-aspartate selective glutamate receptor activity (GO:2000310)2.90001167
126response to mercury ion (GO:0046689)2.87984708
127positive regulation of potassium ion transmembrane transport (GO:1901381)2.87483038
128regulation of membrane repolarization (GO:0060306)2.87068565
129cellular response to sterol (GO:0036315)2.86569276
130cilium movement (GO:0003341)2.86287459
131negative regulation of lipase activity (GO:0060192)2.85748873
132negative regulation of hydrogen peroxide-induced cell death (GO:1903206)2.85601696
133regulation of respiratory system process (GO:0044065)2.84974717
134regulation of plasminogen activation (GO:0010755)2.84740787
135amino-acid betaine metabolic process (GO:0006577)2.84347078
136synaptic vesicle docking involved in exocytosis (GO:0016081)2.83685142
137ethanol metabolic process (GO:0006067)2.83196225
138presynaptic membrane assembly (GO:0097105)2.83019317
139complement activation (GO:0006956)2.80614786
140serine transport (GO:0032329)2.78766219
141regulation of glomerular filtration (GO:0003093)2.77642893
142regulation of synaptic plasticity (GO:0048167)2.75673014
143dermatan sulfate biosynthetic process (GO:0030208)2.74064843
144innervation (GO:0060384)2.73225843
145positive regulation of synaptic transmission, GABAergic (GO:0032230)2.72866079
146dermatan sulfate metabolic process (GO:0030205)2.68654537
147negative regulation of cytosolic calcium ion concentration (GO:0051481)2.66871082
148positive regulation of dendritic spine development (GO:0060999)2.66799416
149female mating behavior (GO:0060180)2.65826798
150membrane repolarization (GO:0086009)2.65141153
151oligodendrocyte differentiation (GO:0048709)2.64348944
152prepulse inhibition (GO:0060134)2.60932819

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1EZH2_22144423_ChIP-Seq_EOC_Human4.93172609
2ESR1_17901129_ChIP-ChIP_LIVER_Mouse4.56326785
3SUZ12_18555785_ChIP-Seq_MESCs_Mouse3.09615830
4SUZ12_18692474_ChIP-Seq_MESCs_Mouse2.96888451
5JARID2_20064375_ChIP-Seq_MESCs_Mouse2.89815529
6SUZ12_16625203_ChIP-ChIP_MESCs_Mouse2.79253265
7EZH2_18974828_ChIP-Seq_MESCs_Mouse2.67064134
8RNF2_18974828_ChIP-Seq_MESCs_Mouse2.67064134
9GBX2_23144817_ChIP-Seq_PC3_Human2.64479354
10JARID2_20075857_ChIP-Seq_MESCs_Mouse2.62554754
11SUZ12_18692474_ChIP-Seq_MEFs_Mouse2.57244142
12SUZ12_18974828_ChIP-Seq_MESCs_Mouse2.55493789
13RXR_22158963_ChIP-Seq_LIVER_Mouse2.54827171
14EED_16625203_ChIP-ChIP_MESCs_Mouse2.52609696
15MTF2_20144788_ChIP-Seq_MESCs_Mouse2.48972005
16FOXO1_23066095_ChIP-Seq_LIVER_Mouse2.44960234
17EZH2_27304074_Chip-Seq_ESCs_Mouse2.44416199
18SUZ12_20075857_ChIP-Seq_MESCs_Mouse2.38457075
19AR_21572438_ChIP-Seq_LNCaP_Human2.34491258
20DROSHA_22980978_ChIP-Seq_HELA_Human2.32547517
21RNF2_27304074_Chip-Seq_ESCs_Mouse2.29175693
22REST_21632747_ChIP-Seq_MESCs_Mouse2.25169388
23LXR_22158963_ChIP-Seq_LIVER_Mouse2.18858381
24SUZ12_27294783_Chip-Seq_ESCs_Mouse2.17528173
25EZH2_27294783_Chip-Seq_ESCs_Mouse2.16252125
26IKZF1_21737484_ChIP-ChIP_HCT116_Human2.14956370
27PPARA_22158963_ChIP-Seq_LIVER_Mouse2.00213164
28NR1I2_20693526_ChIP-Seq_LIVER_Mouse1.98820372
29PPARG_19300518_ChIP-PET_3T3-L1_Mouse1.95202390
30EGR1_23403033_ChIP-Seq_LIVER_Mouse1.89644396
31RARB_27405468_Chip-Seq_BRAIN_Mouse1.84958574
32REST_18959480_ChIP-ChIP_MESCs_Mouse1.72014616
33RCOR2_21632747_ChIP-Seq_MESCs_Mouse1.68122264
34GLI1_17442700_ChIP-ChIP_MESCs_Mouse1.67364028
35MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human1.65354154
36CTBP2_25329375_ChIP-Seq_LNCAP_Human1.62932788
37RNF2_16625203_ChIP-ChIP_MESCs_Mouse1.59841202
38SMAD_19615063_ChIP-ChIP_OVARY_Human1.59786205
39ERG_21242973_ChIP-ChIP_JURKAT_Human1.56249734
40CDX2_19796622_ChIP-Seq_MESCs_Mouse1.54558204
41RING1B_27294783_Chip-Seq_ESCs_Mouse1.54539533
42PHC1_16625203_ChIP-ChIP_MESCs_Mouse1.50229342
43CBX2_27304074_Chip-Seq_ESCs_Mouse1.47953995
44ZFP322A_24550733_ChIP-Seq_MESCs_Mouse1.47025662
45GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.44285597
46CTBP1_25329375_ChIP-Seq_LNCAP_Human1.42807771
47EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.39921928
48SMAD4_21799915_ChIP-Seq_A2780_Human1.38362379
49CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons1.36657803
50RXR_22108803_ChIP-Seq_LS180_Human1.34683472
51E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse1.32013816
52SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.30807315
53PIAS1_25552417_ChIP-Seq_VCAP_Human1.29970312
54PPARD_23176727_ChIP-Seq_KERATINOCYTES_Mouse1.29289852
55P300_19829295_ChIP-Seq_ESCs_Human1.28182731
56ESRRB_18555785_ChIP-Seq_MESCs_Mouse1.25753288
57NR4A2_19515692_ChIP-ChIP_MN9D_Mouse1.24814339
58PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.24561212
59CTCF_27219007_Chip-Seq_Bcells_Human1.20340754
60TP53_20018659_ChIP-ChIP_R1E_Mouse1.20144443
61BCAT_22108803_ChIP-Seq_LS180_Human1.19499813
62CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human1.19354538
63ZFP281_18757296_ChIP-ChIP_E14_Mouse1.19330637
64NR3C1_21868756_ChIP-Seq_MCF10A_Human1.19258198
65TRIM28_17542650_ChIP-ChIP_NTERA2_Human1.18402328
66WT1_25993318_ChIP-Seq_PODOCYTE_Human1.18229457
67SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.18061145
68FOXA2_19822575_ChIP-Seq_HepG2_Human1.17154131
69* AR_25329375_ChIP-Seq_VCAP_Human1.16304919
70SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.15894046
71TCF7L2_21901280_ChIP-Seq_H4IIE_Rat1.14857693
72RING1B_27294783_Chip-Seq_NPCs_Mouse1.14706984
73* EGR1_20690147_ChIP-Seq_ERYTHROLEUKEMIA_Human1.13506441
74SOX2_21211035_ChIP-Seq_LN229_Gbm1.12774747
75OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.12633318
76SMAD3_21741376_ChIP-Seq_EPCs_Human1.12300067
77TRIM28_21343339_ChIP-Seq_HEK293_Human1.12292477
78* AR_19668381_ChIP-Seq_PC3_Human1.10474701
79THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse1.10415784
80SOX9_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse1.09900741
81PBX_27287812_Chip-Seq_EMBYONIC-LIMB_Mouse1.09454361
82TP53_18474530_ChIP-ChIP_U2OS_Human1.08533948
83KDM2B_26808549_Chip-Seq_K562_Human1.07947383
84CEBPB_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.07274431
85TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human1.05617421
86NR3C1_23031785_ChIP-Seq_PC12_Mouse1.05571942
87ZFP57_27257070_Chip-Seq_ESCs_Mouse1.05133495
88LXR_22292898_ChIP-Seq_THP-1_Human1.04128686
89BACH1_22875853_ChIP-PCR_HELA_AND_SCP4_Human1.03535749
90DNAJC2_21179169_ChIP-ChIP_NT2_Human1.03294100
91ZNF217_24962896_ChIP-Seq_MCF-7_Human1.02516216
92TOP2B_26459242_ChIP-Seq_MCF-7_Human1.01796655
93CTNNB1_24651522_ChIP-Seq_LGR5+_INTESTINAL_STEM_Human1.01673184
94SMAD3_22036565_ChIP-Seq_ESCs_Mouse1.01399678
95ARNT_22903824_ChIP-Seq_MCF-7_Human1.01366099
96* STAT3_23295773_ChIP-Seq_U87_Human1.01100684
97RCOR3_21632747_ChIP-Seq_MESCs_Mouse0.99591574
98SMC4_20622854_ChIP-Seq_HELA_Human0.99375123
99MEIS1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse0.98794525
100POU5F1_26923725_Chip-Seq_MESODERM_Mouse0.97867567
101TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.97867567
102ESR1_22446102_ChIP-Seq_UTERUS_Mouse0.97856420
103TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.97479768
104YAP1_20516196_ChIP-Seq_MESCs_Mouse0.96521703
105HTT_18923047_ChIP-ChIP_STHdh_Human0.96140149
106SMAD4_21741376_ChIP-Seq_HESCs_Human0.95441203
107TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse0.93864554
108OLIG2_26023283_ChIP-Seq_AINV15_Mouse0.93001833
109SMAD3_21741376_ChIP-Seq_ESCs_Human0.92891186
110SRY_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse0.92764666
111TP53_16413492_ChIP-PET_HCT116_Human0.92748834
112TFAP2C_20629094_ChIP-Seq_MCF-7_Human0.92601613
113P53_22127205_ChIP-Seq_FIBROBLAST_Human0.91447024
114PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse0.91034872
115LMO2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.90208105
116AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human0.89746019
117UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human0.89066747
118RUNX2_22187159_ChIP-Seq_PCA_Human0.88597831
119TET1_21490601_ChIP-Seq_MESCs_Mouse0.88184472
120VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human0.87639182
121ESR1_15608294_ChIP-ChIP_MCF-7_Human0.85890963
122TCF4_23295773_ChIP-Seq_U87_Human0.85022936
123CTNNB1_20460455_ChIP-Seq_HCT116_Human0.84919208
124MYC_19915707_ChIP-ChIP_AK7_Human0.84826832
125SMAD3_21741376_ChIP-Seq_HESCs_Human0.83824488
126EP300_20729851_ChIP-Seq_FORBRAIN_MIDBRAIN_LIMB_HEART_Mouse0.83538034
127AHR_22903824_ChIP-Seq_MCF-7_Human0.83420062
128ESR2_21235772_ChIP-Seq_MCF-7_Human0.83315438
129RNF2_27304074_Chip-Seq_NSC_Mouse0.83247471
130* OCT4_19829295_ChIP-Seq_ESCs_Human0.82817390
131HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse0.82713183
132SCL_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.80830331
133ZFP281_27345836_Chip-Seq_ESCs_Mouse0.80590239
134NEUROD2_26341353_ChIP-Seq_CORTEX_Mouse0.78943585
135KLF4_19829295_ChIP-Seq_ESCs_Human0.77864949
136HNF4A_19822575_ChIP-Seq_HepG2_Human0.75653318
137WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse0.74256894
138ETS2_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse0.74126668
139CEBPB_23403033_ChIP-Seq_LIVER_Mouse0.73805768
140POU5F1_16518401_ChIP-PET_MESCs_Mouse0.72253528
141RAD21_21589869_ChIP-Seq_MESCs_Mouse0.70592515
142ESR1_20079471_ChIP-ChIP_T-47D_Human0.69799271

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0004859_abnormal_synaptic_plasticity4.56879518
2MP0002139_abnormal_hepatobiliary_system4.45644256
3MP0004858_abnormal_nervous_system3.63510128
4MP0003690_abnormal_glial_cell3.57007265
5MP0005646_abnormal_pituitary_gland3.47908905
6MP0005423_abnormal_somatic_nervous3.22089091
7MP0003635_abnormal_synaptic_transmissio3.14256758
8MP0003880_abnormal_central_pattern3.10395958
9MP0005365_abnormal_bile_salt2.99990782
10MP0005085_abnormal_gallbladder_physiolo2.95742383
11MP0008875_abnormal_xenobiotic_pharmacok2.93199253
12MP0003136_yellow_coat_color2.91827341
13MP0009780_abnormal_chondrocyte_physiolo2.80252909
14MP0004270_analgesia2.78399434
15MP0009745_abnormal_behavioral_response2.75305617
16MP0002064_seizures2.71891765
17MP0009046_muscle_twitch2.70809128
18MP0001486_abnormal_startle_reflex2.67877059
19MP0003329_amyloid_beta_deposits2.54455511
20MP0002063_abnormal_learning/memory/cond2.51857253
21MP0004885_abnormal_endolymph2.42506174
22MP0002572_abnormal_emotion/affect_behav2.32847188
23MP0001440_abnormal_grooming_behavior2.30342427
24MP0005360_urolithiasis2.30202155
25MP0001968_abnormal_touch/_nociception2.23722896
26MP0003195_calcinosis2.18716710
27MP0002272_abnormal_nervous_system2.04203369
28MP0002736_abnormal_nociception_after2.02669866
29MP0009384_cardiac_valve_regurgitation2.02064975
30MP0002734_abnormal_mechanical_nocicepti1.95433626
31MP0003634_abnormal_glial_cell1.93020780
32MP0001501_abnormal_sleep_pattern1.81046684
33MP0005167_abnormal_blood-brain_barrier1.80902965
34MP0008569_lethality_at_weaning1.80168151
35MP0003075_altered_response_to1.78696035
36MP0010329_abnormal_lipoprotein_level1.78463144
37MP0002254_reproductive_system_inflammat1.77783173
38MP0000778_abnormal_nervous_system1.77615197
39MP0002653_abnormal_ependyma_morphology1.75057778
40MP0001502_abnormal_circadian_rhythm1.72804297
41MP0002557_abnormal_social/conspecific_i1.72744894
42MP0005645_abnormal_hypothalamus_physiol1.71276135
43MP0003633_abnormal_nervous_system1.69729923
44MP0002733_abnormal_thermal_nociception1.68372783
45MP0001984_abnormal_olfaction1.66468098
46MP0002067_abnormal_sensory_capabilities1.66087737
47MP0003868_abnormal_feces_composition1.64765306
48MP0003252_abnormal_bile_duct1.62916863
49MP0001485_abnormal_pinna_reflex1.59676360
50MP0002638_abnormal_pupillary_reflex1.53966515
51MP0001970_abnormal_pain_threshold1.46834854
52MP0005332_abnormal_amino_acid1.36715711
53MP0003631_nervous_system_phenotype1.36247270
54MP0001666_abnormal_nutrient_absorption1.34650758
55MP0004142_abnormal_muscle_tone1.30598107
56MP0001986_abnormal_taste_sensitivity1.29151332
57MP0005386_behavior/neurological_phenoty1.27676254
58MP0004924_abnormal_behavior1.27676254
59MP0005551_abnormal_eye_electrophysiolog1.26954507
60MP0000604_amyloidosis1.26740752
61MP0002138_abnormal_hepatobiliary_system1.22638307
62MP0002735_abnormal_chemical_nociception1.21388761
63MP0002882_abnormal_neuron_morphology1.20453906
64MP0003183_abnormal_peptide_metabolism1.19504524
65MP0000955_abnormal_spinal_cord1.19382652
66MP0003191_abnormal_cellular_cholesterol1.19319863
67MP0002909_abnormal_adrenal_gland1.18928700
68MP0005670_abnormal_white_adipose1.16732350
69MP0005623_abnormal_meninges_morphology1.15266316
70MP0003279_aneurysm1.13862487
71MP0001905_abnormal_dopamine_level1.12206764
72MP0002152_abnormal_brain_morphology1.11790179
73MP0002876_abnormal_thyroid_physiology1.11410410
74MP0009840_abnormal_foam_cell1.11310694
75MP0003632_abnormal_nervous_system1.10734250
76MP0002089_abnormal_postnatal_growth/wei1.10703070
77MP0002066_abnormal_motor_capabilities/c1.10222484
78MP0008874_decreased_physiological_sensi1.09293448
79MP0003137_abnormal_impulse_conducting1.09240882
80MP0003878_abnormal_ear_physiology1.08709952
81MP0005377_hearing/vestibular/ear_phenot1.08709952
82MP0004215_abnormal_myocardial_fiber1.07892356
83MP0000920_abnormal_myelination1.06163057
84MP0003011_delayed_dark_adaptation1.05828940
85MP0002118_abnormal_lipid_homeostasis1.05092977
86MP0005253_abnormal_eye_physiology1.02409870
87MP0001963_abnormal_hearing_physiology1.02383172
88MP0001853_heart_inflammation1.00229353
89MP0002090_abnormal_vision0.99663160
90MP0005535_abnormal_body_temperature0.95252743
91MP0004742_abnormal_vestibular_system0.92058743
92MP0000631_abnormal_neuroendocrine_gland0.90560741
93MP0002229_neurodegeneration0.89147493
94MP0005379_endocrine/exocrine_gland_phen0.88994808
95MP0000026_abnormal_inner_ear0.88520274
96MP0004811_abnormal_neuron_physiology0.88455531
97MP0002184_abnormal_innervation0.88200874
98MP0000049_abnormal_middle_ear0.87507672
99MP0000566_synostosis0.83959829
100MP0006276_abnormal_autonomic_nervous0.82698798
101MP0003879_abnormal_hair_cell0.81933190
102MP0002249_abnormal_larynx_morphology0.78268791
103MP0000751_myopathy0.78208247
104MP0006072_abnormal_retinal_apoptosis0.75945741
105MP0003938_abnormal_ear_development0.75906443
106MP0005171_absent_coat_pigmentation0.74977432
107MP0002822_catalepsy0.73233927
108MP0005595_abnormal_vascular_smooth0.70089745
109MP0005166_decreased_susceptibility_to0.69814606
110MP0001299_abnormal_eye_distance/0.69109735
111MP0005584_abnormal_enzyme/coenzyme_acti0.67109653
112MP0002752_abnormal_somatic_nervous0.66990233
113MP0001177_atelectasis0.66260544
114MP0000428_abnormal_craniofacial_morphol0.64813677
115MP0002069_abnormal_eating/drinking_beha0.63892411
116MP0004130_abnormal_muscle_cell0.63636362
117MP0002971_abnormal_brown_adipose0.63396115
118MP0004019_abnormal_vitamin_homeostasis0.63368874
119MP0008872_abnormal_physiological_respon0.63334355
120MP0003172_abnormal_lysosome_physiology0.59861081
121MP0001943_abnormal_respiration0.57382715
122MP0005165_increased_susceptibility_to0.56321236
123MP0001529_abnormal_vocalization0.55031376
124MP0000609_abnormal_liver_physiology0.52917118
125MP0000639_abnormal_adrenal_gland0.52140997
126MP0000579_abnormal_nail_morphology0.51898135
127MP0001764_abnormal_homeostasis0.49335316
128MP0005448_abnormal_energy_balance0.46310301
129MP0005636_abnormal_mineral_homeostasis0.43356705

Predicted human phenotypes

RankGene SetZ-score
1Aplasia involving bones of the extremities (HP:0009825)6.76960548
2Aplasia involving bones of the upper limbs (HP:0009823)6.76960548
3Aplasia of the phalanges of the hand (HP:0009802)6.76960548
4Complement deficiency (HP:0004431)6.46935690
5Abnormality of monocarboxylic acid metabolism (HP:0010996)6.35663982
6Abnormality of aromatic amino acid family metabolism (HP:0004338)6.01890403
7Deep venous thrombosis (HP:0002625)5.74848563
8Megalencephaly (HP:0001355)5.34582665
9Prolonged partial thromboplastin time (HP:0003645)5.30415764
10Abnormality of complement system (HP:0005339)4.87083796
11Hypobetalipoproteinemia (HP:0003563)4.62895713
12Diplopia (HP:0000651)4.45173182
13Abnormality of binocular vision (HP:0011514)4.45173182
14Focal motor seizures (HP:0011153)4.41196351
15Neurofibrillary tangles (HP:0002185)4.31197938
16Hemiparesis (HP:0001269)4.30754125
17Systemic lupus erythematosus (HP:0002725)4.29659598
18Hemiplegia (HP:0002301)4.22731252
19Abnormal ciliary motility (HP:0012262)4.19594523
20Joint hemorrhage (HP:0005261)4.05138958
21Hyperlipoproteinemia (HP:0010980)4.03780182
22Abnormal respiratory motile cilium physiology (HP:0012261)3.94980166
23Myokymia (HP:0002411)3.89203236
24Glomerulonephritis (HP:0000099)3.88140576
25Epileptic encephalopathy (HP:0200134)3.43012164
26Spontaneous abortion (HP:0005268)3.38759053
27Hypoplastic left heart (HP:0004383)3.37873462
28Conjugated hyperbilirubinemia (HP:0002908)3.36743921
29Respiratory insufficiency due to defective ciliary clearance (HP:0200073)3.36450694
30Cerebral inclusion bodies (HP:0100314)3.31844602
31Xanthomatosis (HP:0000991)3.28987444
32Focal seizures (HP:0007359)3.19930820
33Supranuclear gaze palsy (HP:0000605)3.12440524
34Visual hallucinations (HP:0002367)3.09222453
35Intrahepatic cholestasis (HP:0001406)3.03933322
36Humeroradial synostosis (HP:0003041)3.03535397
37Synostosis involving the elbow (HP:0003938)3.03535397
38Progressive cerebellar ataxia (HP:0002073)2.98410106
39Abnormal respiratory motile cilium morphology (HP:0005938)2.94306137
40Abnormal respiratory epithelium morphology (HP:0012253)2.94306137
41Torticollis (HP:0000473)2.90147910
42Rhinitis (HP:0012384)2.90138408
43Long nose (HP:0003189)2.90008871
44Generalized tonic-clonic seizures (HP:0002069)2.83318181
45Mixed hearing impairment (HP:0000410)2.83178435
46Abnormality of the axillary hair (HP:0100134)2.80292323
47Abnormality of secondary sexual hair (HP:0009888)2.80292323
48Short middle phalanx of the 5th finger (HP:0004220)2.80253729
49Action tremor (HP:0002345)2.80064797
50Split foot (HP:0001839)2.76819382
51Hypolipoproteinemia (HP:0010981)2.76650030
52Narrow nasal bridge (HP:0000446)2.73937471
53Abnormality of the common coagulation pathway (HP:0010990)2.73029421
54Dynein arm defect of respiratory motile cilia (HP:0012255)2.72962510
55Absent/shortened dynein arms (HP:0200106)2.72962510
56Dysdiadochokinesis (HP:0002075)2.71091282
57Tetraparesis (HP:0002273)2.69835608
58Abnormality of the dental pulp (HP:0006479)2.67993489
59Postural instability (HP:0002172)2.65787721
60Spastic gait (HP:0002064)2.64218003
61Nephritis (HP:0000123)2.58755274
62Broad alveolar ridges (HP:0000187)2.56811085
63Clumsiness (HP:0002312)2.56714282
64Hypoplastic heart (HP:0001961)2.53835477
65Abnormal eating behavior (HP:0100738)2.50464007
66Short hallux (HP:0010109)2.49618890
67Abnormality of the intrinsic pathway (HP:0010989)2.48154731
68Maternal diabetes (HP:0009800)2.47229748
69Median cleft lip (HP:0000161)2.45262669
70Focal dystonia (HP:0004373)2.44524391
71Abnormality of the dental root (HP:0006486)2.41228379
72Taurodontia (HP:0000679)2.41228379
73Abnormality of permanent molar morphology (HP:0011071)2.41228379
74Abnormality of glycine metabolism (HP:0010895)2.37985084
75Abnormality of serine family amino acid metabolism (HP:0010894)2.37985084
76Abnormality of the level of lipoprotein cholesterol (HP:0010979)2.34923647
77Craniofacial dystonia (HP:0012179)2.33906961
78Confusion (HP:0001289)2.32957871
79Dry hair (HP:0011359)2.32915344
80Aplasia/Hypoplasia of the hallux (HP:0008362)2.32462967
81Hyperglycinemia (HP:0002154)2.30101446
82Aplasia/Hypoplasia of the middle phalanx of the 5th finger (HP:0009161)2.30041859
83Hypoalphalipoproteinemia (HP:0003233)2.29840022
84Clonus (HP:0002169)2.28138299
85Status epilepticus (HP:0002133)2.27989935
86Papilledema (HP:0001085)2.27694574
87Hyperglycinuria (HP:0003108)2.26274376
88Cerebral hypomyelination (HP:0006808)2.25605844
89Abnormality of molar (HP:0011077)2.24420980
90Abnormality of molar morphology (HP:0011070)2.24420980
91Delusions (HP:0000746)2.23832869
92Depression (HP:0000716)2.17832924
93Obstructive sleep apnea (HP:0002870)2.17519707
94Mutism (HP:0002300)2.16027690
95Urinary bladder sphincter dysfunction (HP:0002839)2.16026198
96Truncal ataxia (HP:0002078)2.14161491
97Abnormality of the middle phalanges of the toes (HP:0010183)2.13932440
98Scanning speech (HP:0002168)2.12188635
99Neonatal short-limb short stature (HP:0008921)2.10228427
100Back pain (HP:0003418)2.09503721
101Abnormality of the middle phalanx of the 5th finger (HP:0004219)2.08897741
102Delayed CNS myelination (HP:0002188)2.07958511
103Atrioventricular block (HP:0001678)2.07797314
104Aplasia/Hypoplasia of the phalanges of the 5th finger (HP:0009376)2.06538775
105Bronchomalacia (HP:0002780)2.06092315
106Paraparesis (HP:0002385)2.05276106
107Adactyly (HP:0009776)2.04928718
108Epileptiform EEG discharges (HP:0011182)2.03743992
109Fat malabsorption (HP:0002630)2.03565040
110Abnormality of the periventricular white matter (HP:0002518)2.03164301
111Abnormality of glutamine family amino acid metabolism (HP:0010902)2.02139987
112Absence seizures (HP:0002121)2.00133377
113Mitral stenosis (HP:0001718)1.99920075
114Akinesia (HP:0002304)1.99675514
115Abnormality of pyrimidine metabolism (HP:0004353)1.99306014
116Dialeptic seizures (HP:0011146)1.98508320
117Dysmetria (HP:0001310)1.98490967
118Irritability (HP:0000737)1.98275870
119Tetraplegia (HP:0002445)1.95657950
120Abnormal gallbladder physiology (HP:0012438)1.94813809
121Cholecystitis (HP:0001082)1.94813809
122Annular pancreas (HP:0001734)1.94469582
123Retinal atrophy (HP:0001105)1.93932640
124Anxiety (HP:0000739)1.93795247
125Atonic seizures (HP:0010819)1.93733233
126Spastic tetraparesis (HP:0001285)1.93580841
127Fibular aplasia (HP:0002990)1.91312362
128Febrile seizures (HP:0002373)1.91121861
129Abnormality of the phalanges of the 5th finger (HP:0004213)1.90262535
130Limb dystonia (HP:0002451)1.89825380
131Intention tremor (HP:0002080)1.88914122
132Neuronal loss in central nervous system (HP:0002529)1.88532087
133Recurrent gram-negative bacterial infections (HP:0005420)1.87868698
134Abnormal atrioventricular conduction (HP:0005150)1.86637665
135Lower limb muscle weakness (HP:0007340)1.85909844
136Hyperammonemia (HP:0001987)1.85775444
137Hypercholesterolemia (HP:0003124)1.85521420
138Poor eye contact (HP:0000817)1.83613438
139Urinary urgency (HP:0000012)1.83537754
140Ankle clonus (HP:0011448)1.82764804
141Heart block (HP:0012722)1.81638042
142Morphological abnormality of the pyramidal tract (HP:0002062)1.81473977
143Oligodactyly (hands) (HP:0001180)1.79832749
144Polyphagia (HP:0002591)1.79758955
145Rigidity (HP:0002063)1.78321324
146Peripheral hypomyelination (HP:0007182)1.76355181
147Bradykinesia (HP:0002067)1.73945293
148Aplasia/Hypoplasia of the 5th finger (HP:0006262)1.72149629
149Increased circulating renin level (HP:0000848)1.70935874
150Cutaneous syndactyly (HP:0012725)1.70354883
151Microglossia (HP:0000171)1.69682698
152Hyperventilation (HP:0002883)1.69256594
153Metabolic alkalosis (HP:0200114)1.68690411
154Selective tooth agenesis (HP:0001592)1.68561909
155Athetosis (HP:0002305)1.67860226
156Hypoplastic pelvis (HP:0008839)1.65257519
157Abnormality of chromosome segregation (HP:0002916)1.63941882
158Impaired vibration sensation in the lower limbs (HP:0002166)1.63797721
159Facial shape deformation (HP:0011334)1.63445941
160Potter facies (HP:0002009)1.63445941

Predicted kinase interactions (KEA)

RankGene SetZ-score
1EPHA44.06370250
2NTRK23.78552611
3LMTK23.64899645
4TNIK3.17765005
5NTRK33.10661284
6PHKG22.87137331
7PHKG12.87137331
8PRKD32.27463744
9MAP3K92.16159895
10MARK12.03461066
11CASK1.97883914
12PAK61.97704615
13MUSK1.96537835
14MINK11.89394276
15MAP3K41.74358340
16PRKCG1.68636554
17MAP2K71.66843193
18MAPK131.66446904
19RIPK11.66295140
20DAPK21.60634396
21MAPK121.52414115
22NEK61.50767760
23TYRO31.50625103
24CAMKK11.44845440
25NTRK11.43796760
26TRIB31.38512781
27CDK51.37289186
28PDK21.36351206
29SGK2231.30345192
30SGK4941.30345192
31SGK21.28123174
32FES1.26147310
33PNCK1.20790667
34MAPK71.16696529
35SIK11.11977524
36PINK11.11726379
37KSR21.08539676
38SGK31.07849934
39FGR1.07280225
40GRK51.05036507
41DYRK1A1.02850001
42CAMK1G1.02819033
43PAK31.02408416
44LATS20.99181622
45CAMK2A0.92864763
46PRKCH0.91431028
47STK380.90892936
48PRKCE0.89873970
49ROCK20.89668979
50CDK150.88690399
51PLK20.87618076
52UHMK10.87171582
53ROCK10.87166539
54RIPK40.86682124
55DAPK10.85557005
56CDK180.84878071
57MARK20.83378329
58SIK20.83063580
59BRSK10.82252868
60KSR10.80276321
61MAPK150.80028514
62CDK11A0.75844430
63MAP2K40.75686489
64CDK140.74345476
65BMX0.74186545
66ADRBK10.72632756
67TNK20.70662224
68PRPF4B0.69729909
69SGK10.66985162
70MAP3K20.66902588
71CDC42BPA0.66164267
72CAMK2G0.66099706
73ERBB20.65741645
74PRKCZ0.63167337
75CDK190.63000231
76IRAK30.62576570
77ARAF0.62000284
78OXSR10.61552294
79CAMK40.61495561
80CAMK10.60925140
81BMPR20.60884668
82CAMK2B0.60687079
83CAMKK20.58368175
84RPS6KA30.58260252
85ALK0.55504068
86CAMK1D0.54777668
87MAP3K130.54629091
88DDR20.53861963
89FGFR20.53487041
90CDK30.53037991
91PTK2B0.51709067
92PKN10.51606053
93RET0.51540240
94PRKCA0.51162382
95PDPK10.50838289
96MAPK100.49082160
97DMPK0.48959130
98FYN0.48155906
99STK110.46173176
100PDK10.44472392
101SRC0.44207666
102MAPKAPK50.44005844
103PRKG10.43382007
104CAMK2D0.43215382
105MAP3K110.40629966
106MAPK40.40208120
107PIK3CA0.39747202
108PRKG20.39419558
109IGF1R0.39032374
110PRKACG0.38839511
111PRKCQ0.38382704
112PRKACA0.38199013
113MOS0.38070227
114PRKCB0.37405735
115MAP2K60.37114668
116MKNK20.36592507
117MAP3K10.35848060
118DAPK30.35493605
119CSNK1D0.35425133
120CCNB10.34272032
121CSNK1A10.33051890
122RAF10.32626067
123ABL20.30614696
124CSNK1E0.30373067
125PRKD10.30275134
126CSNK1G20.29760135

Predicted pathways (KEGG)

RankGene SetZ-score
1Nitrogen metabolism_Homo sapiens_hsa009105.49287847
2Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004003.82027085
3Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049643.12206142
4Nicotine addiction_Homo sapiens_hsa050333.05171232
5Fatty acid biosynthesis_Homo sapiens_hsa000612.88002275
6Primary bile acid biosynthesis_Homo sapiens_hsa001202.86874243
7Complement and coagulation cascades_Homo sapiens_hsa046102.81716199
8GABAergic synapse_Homo sapiens_hsa047272.57720380
9Caffeine metabolism_Homo sapiens_hsa002322.56943462
10Glycine, serine and threonine metabolism_Homo sapiens_hsa002602.39948342
11Ascorbate and aldarate metabolism_Homo sapiens_hsa000532.35389202
12Glutamatergic synapse_Homo sapiens_hsa047242.30502323
13Drug metabolism - cytochrome P450_Homo sapiens_hsa009822.25792443
14Histidine metabolism_Homo sapiens_hsa003402.25687276
15Salivary secretion_Homo sapiens_hsa049702.10699941
16Retinol metabolism_Homo sapiens_hsa008302.09300000
17Gastric acid secretion_Homo sapiens_hsa049711.99142213
18Circadian entrainment_Homo sapiens_hsa047131.95178280
19Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049611.95127253
20Insulin secretion_Homo sapiens_hsa049111.94183059
21Phenylalanine metabolism_Homo sapiens_hsa003601.93999149
22Olfactory transduction_Homo sapiens_hsa047401.91874598
23Synaptic vesicle cycle_Homo sapiens_hsa047211.91779301
24Retrograde endocannabinoid signaling_Homo sapiens_hsa047231.91308402
25Morphine addiction_Homo sapiens_hsa050321.87952749
26Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009801.81446436
27Chemical carcinogenesis_Homo sapiens_hsa052041.78439529
28Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006301.74638349
29beta-Alanine metabolism_Homo sapiens_hsa004101.64050512
30Long-term potentiation_Homo sapiens_hsa047201.63353581
31Pentose and glucuronate interconversions_Homo sapiens_hsa000401.54261173
32Steroid hormone biosynthesis_Homo sapiens_hsa001401.53442705
33Tyrosine metabolism_Homo sapiens_hsa003501.49560494
34Amphetamine addiction_Homo sapiens_hsa050311.48312793
35Calcium signaling pathway_Homo sapiens_hsa040201.35771036
36Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049601.32035241
37Taste transduction_Homo sapiens_hsa047421.27718881
38Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042611.26256064
39Renin secretion_Homo sapiens_hsa049241.25807880
40Vasopressin-regulated water reabsorption_Homo sapiens_hsa049621.25570353
41Drug metabolism - other enzymes_Homo sapiens_hsa009831.25224745
42Tryptophan metabolism_Homo sapiens_hsa003801.24972705
43Bile secretion_Homo sapiens_hsa049761.24571378
44Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010401.24192122
45Cocaine addiction_Homo sapiens_hsa050301.24140976
46Aldosterone synthesis and secretion_Homo sapiens_hsa049251.22183749
47Fatty acid metabolism_Homo sapiens_hsa012121.20577023
48Valine, leucine and isoleucine degradation_Homo sapiens_hsa002801.16386429
49Cholinergic synapse_Homo sapiens_hsa047251.16266185
50cAMP signaling pathway_Homo sapiens_hsa040241.15521624
51Long-term depression_Homo sapiens_hsa047301.15464658
52Dopaminergic synapse_Homo sapiens_hsa047281.15417578
53Dorso-ventral axis formation_Homo sapiens_hsa043201.14909800
54Neuroactive ligand-receptor interaction_Homo sapiens_hsa040801.11801320
55Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005331.10190643
56Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002501.08948496
57Serotonergic synapse_Homo sapiens_hsa047261.06971717
582-Oxocarboxylic acid metabolism_Homo sapiens_hsa012101.04777505
59Melanogenesis_Homo sapiens_hsa049161.04186853
60Gap junction_Homo sapiens_hsa045401.03443627
61Linoleic acid metabolism_Homo sapiens_hsa005911.02168991
62Mineral absorption_Homo sapiens_hsa049781.01913296
63Carbohydrate digestion and absorption_Homo sapiens_hsa049731.00138585
64Circadian rhythm_Homo sapiens_hsa047100.98146912
65Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005340.98124572
66Biosynthesis of amino acids_Homo sapiens_hsa012300.96933977
67Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.96021561
68Pancreatic secretion_Homo sapiens_hsa049720.95339806
69Pyruvate metabolism_Homo sapiens_hsa006200.95314521
70Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.93176698
71Oxytocin signaling pathway_Homo sapiens_hsa049210.92612271
72PPAR signaling pathway_Homo sapiens_hsa033200.90410432
73Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.88906567
74GnRH signaling pathway_Homo sapiens_hsa049120.88299342
75Cysteine and methionine metabolism_Homo sapiens_hsa002700.88219659
76Cardiac muscle contraction_Homo sapiens_hsa042600.86544064
77Phospholipase D signaling pathway_Homo sapiens_hsa040720.84570966
78Peroxisome_Homo sapiens_hsa041460.81697984
79Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.79825893
80Thyroid hormone synthesis_Homo sapiens_hsa049180.79628258
81Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.78929020
82ABC transporters_Homo sapiens_hsa020100.76904937
83Fatty acid degradation_Homo sapiens_hsa000710.76091290
84Taurine and hypotaurine metabolism_Homo sapiens_hsa004300.74886461
85Estrogen signaling pathway_Homo sapiens_hsa049150.74562815
86cGMP-PKG signaling pathway_Homo sapiens_hsa040220.73425893
87Steroid biosynthesis_Homo sapiens_hsa001000.72414590
88Thyroid hormone signaling pathway_Homo sapiens_hsa049190.72345167
89Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047500.72200690
90Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054120.72076162
91Cyanoamino acid metabolism_Homo sapiens_hsa004600.69614533
92Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001300.68920288
93Citrate cycle (TCA cycle)_Homo sapiens_hsa000200.68275104
94Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.67817982
95Phosphatidylinositol signaling system_Homo sapiens_hsa040700.65625718
96Axon guidance_Homo sapiens_hsa043600.65504305
97Glycerophospholipid metabolism_Homo sapiens_hsa005640.64575462
98Carbon metabolism_Homo sapiens_hsa012000.64546979
99African trypanosomiasis_Homo sapiens_hsa051430.64109141
100Sphingolipid signaling pathway_Homo sapiens_hsa040710.63820731
101Basal cell carcinoma_Homo sapiens_hsa052170.62021713
102Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005320.60531896
103Starch and sucrose metabolism_Homo sapiens_hsa005000.60328736
104Vascular smooth muscle contraction_Homo sapiens_hsa042700.58287194
105Synthesis and degradation of ketone bodies_Homo sapiens_hsa000720.57409466
106Dilated cardiomyopathy_Homo sapiens_hsa054140.57116594
107Arachidonic acid metabolism_Homo sapiens_hsa005900.56280941
108Hedgehog signaling pathway_Homo sapiens_hsa043400.55104321
109Glioma_Homo sapiens_hsa052140.55044879
110ErbB signaling pathway_Homo sapiens_hsa040120.54907450
111Arginine biosynthesis_Homo sapiens_hsa002200.53937802
112Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.53493062
113Sphingolipid metabolism_Homo sapiens_hsa006000.53340365
114Butanoate metabolism_Homo sapiens_hsa006500.49513737
115Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.48780559
116Type II diabetes mellitus_Homo sapiens_hsa049300.47821455
117Collecting duct acid secretion_Homo sapiens_hsa049660.47691882
118Glycerolipid metabolism_Homo sapiens_hsa005610.45818769
119Choline metabolism in cancer_Homo sapiens_hsa052310.45806758
120Staphylococcus aureus infection_Homo sapiens_hsa051500.44780962
121Wnt signaling pathway_Homo sapiens_hsa043100.44759982
122Ether lipid metabolism_Homo sapiens_hsa005650.42595290
123Type I diabetes mellitus_Homo sapiens_hsa049400.42352791
124Adipocytokine signaling pathway_Homo sapiens_hsa049200.39924048
125Glucagon signaling pathway_Homo sapiens_hsa049220.39369948
126Fructose and mannose metabolism_Homo sapiens_hsa000510.38870520
127Vitamin B6 metabolism_Homo sapiens_hsa007500.38478918
128Prion diseases_Homo sapiens_hsa050200.38366011
129Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.36818022
130Rap1 signaling pathway_Homo sapiens_hsa040150.36349797
131MAPK signaling pathway_Homo sapiens_hsa040100.35253382
132Fat digestion and absorption_Homo sapiens_hsa049750.34424675
133Propanoate metabolism_Homo sapiens_hsa006400.34322001
134Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.33025546
135Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.30193013
136Lysosome_Homo sapiens_hsa041420.29761726
137SNARE interactions in vesicular transport_Homo sapiens_hsa041300.27154519
138Arginine and proline metabolism_Homo sapiens_hsa003300.26486597
139Lysine degradation_Homo sapiens_hsa003100.25834384

Most similar genes based on co-expression Upload to Enrichr

Tissue Expression Export image »

Cell Line Expression Export image »