SLC17A6

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1pyrimidine nucleobase catabolic process (GO:0006208)8.64509227
2nucleobase catabolic process (GO:0046113)6.93684441
3neuron cell-cell adhesion (GO:0007158)5.52321906
4regulation of short-term neuronal synaptic plasticity (GO:0048172)5.51299722
5positive regulation of calcium ion-dependent exocytosis (GO:0045956)5.12848202
6regulation of synaptic vesicle exocytosis (GO:2000300)4.92186916
7behavioral response to nicotine (GO:0035095)4.82979186
8synaptic vesicle exocytosis (GO:0016079)4.77322044
9vocalization behavior (GO:0071625)4.72156966
10regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor act4.65962419
11establishment of mitochondrion localization (GO:0051654)4.55672931
12central nervous system projection neuron axonogenesis (GO:0021952)4.55044137
13neuron recognition (GO:0008038)4.53540067
14synaptic vesicle maturation (GO:0016188)4.42409722
15protein localization to synapse (GO:0035418)4.39736632
16glutamate secretion (GO:0014047)4.36661319
17neuronal action potential propagation (GO:0019227)4.35871982
18regulation of synaptic vesicle transport (GO:1902803)4.30585417
19retinal ganglion cell axon guidance (GO:0031290)4.22055089
20regulation of glutamate receptor signaling pathway (GO:1900449)4.19081739
21layer formation in cerebral cortex (GO:0021819)4.10123386
22mitochondrion transport along microtubule (GO:0047497)4.09742587
23establishment of mitochondrion localization, microtubule-mediated (GO:0034643)4.09742587
24positive regulation of excitatory postsynaptic membrane potential (GO:2000463)4.04298487
25positive regulation of dendritic spine morphogenesis (GO:0061003)4.03366839
26axonal fasciculation (GO:0007413)4.03151268
27neurotransmitter secretion (GO:0007269)3.99722014
28regulation of N-methyl-D-aspartate selective glutamate receptor activity (GO:2000310)3.96492700
29proline transport (GO:0015824)3.87478171
30ionotropic glutamate receptor signaling pathway (GO:0035235)3.87381464
31locomotory exploration behavior (GO:0035641)3.84235274
32transmission of nerve impulse (GO:0019226)3.78371231
33positive regulation of synaptic transmission, GABAergic (GO:0032230)3.77714445
34mechanosensory behavior (GO:0007638)3.74456354
35presynaptic membrane assembly (GO:0097105)3.74306812
36positive regulation of potassium ion transmembrane transporter activity (GO:1901018)3.74263314
37cerebellar Purkinje cell differentiation (GO:0021702)3.73652590
38postsynaptic membrane organization (GO:0001941)3.73518270
39central nervous system neuron axonogenesis (GO:0021955)3.72748949
40gamma-aminobutyric acid signaling pathway (GO:0007214)3.70227788
41positive regulation of mitochondrial membrane permeability involved in apoptotic process (GO:19021103.69914078
42mitochondrial outer membrane permeabilization involved in programmed cell death (GO:1902686)3.69914078
43glutamate receptor signaling pathway (GO:0007215)3.69063887
44negative regulation of dendrite morphogenesis (GO:0050774)3.67024386
45neuromuscular process controlling posture (GO:0050884)3.65724874
46presynaptic membrane organization (GO:0097090)3.64921597
47regulation of feeding behavior (GO:0060259)3.62723542
48cell migration in hindbrain (GO:0021535)3.50468792
49activation of protein kinase A activity (GO:0034199)3.50169037
50regulation of inhibitory postsynaptic membrane potential (GO:0060080)3.49988639
51membrane depolarization during action potential (GO:0086010)3.49841335
52response to histamine (GO:0034776)3.49299000
53positive regulation of synapse assembly (GO:0051965)3.49152824
54negative regulation of axon guidance (GO:1902668)3.47971881
55negative regulation of microtubule polymerization (GO:0031115)3.47921302
56dendritic spine morphogenesis (GO:0060997)3.47781858
57negative regulation of synaptic transmission, glutamatergic (GO:0051967)3.47288671
58protein localization to cilium (GO:0061512)3.47095279
59mating behavior (GO:0007617)3.46707797
60regulation of atrial cardiac muscle cell membrane depolarization (GO:0060371)3.44505228
61exploration behavior (GO:0035640)3.44362236
62olfactory bulb development (GO:0021772)3.44029143
63dendritic spine organization (GO:0097061)3.43668790
64synaptic vesicle docking involved in exocytosis (GO:0016081)3.43531765
65regulation of respiratory gaseous exchange by neurological system process (GO:0002087)3.43041121
66* neurotransmitter transport (GO:0006836)3.42484008
67regulation of neuronal synaptic plasticity (GO:0048168)3.42004582
68positive regulation of mitochondrial fission (GO:0090141)3.41850908
69response to pheromone (GO:0019236)3.37550858
70neuron-neuron synaptic transmission (GO:0007270)3.32811399
71axon extension (GO:0048675)3.30242399
72negative regulation of synaptic transmission, GABAergic (GO:0032229)3.29467587
73cellular potassium ion homeostasis (GO:0030007)3.29360590
74regulation of synapse structural plasticity (GO:0051823)3.26873686
75regulation of long-term neuronal synaptic plasticity (GO:0048169)3.26835740
76neuromuscular synaptic transmission (GO:0007274)3.25835121
77regulation of protein kinase A signaling (GO:0010738)3.25050262
78synaptic transmission, glutamatergic (GO:0035249)3.24834561
79membrane depolarization during cardiac muscle cell action potential (GO:0086012)3.24095976
80gamma-aminobutyric acid transport (GO:0015812)3.22645834
81calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules (GO:0016339)3.21498903
82synapse assembly (GO:0007416)3.20202646
83positive regulation of potassium ion transmembrane transport (GO:1901381)3.17378833
84neurotransmitter-gated ion channel clustering (GO:0072578)3.13848199
85positive regulation of synaptic transmission, dopaminergic (GO:0032226)3.12283761
86regulation of synaptic transmission, glutamatergic (GO:0051966)3.11745472
87auditory behavior (GO:0031223)3.11629151
88regulation of postsynaptic membrane potential (GO:0060078)3.11299320
89negative regulation of dendrite development (GO:2000171)3.10563798
90regulation of axon guidance (GO:1902667)3.09956958
91vesicle transport along microtubule (GO:0047496)3.09198886
92G-protein coupled glutamate receptor signaling pathway (GO:0007216)3.08388163
93regulation of collateral sprouting (GO:0048670)3.07256368
94regulation of neurotransmitter secretion (GO:0046928)3.06642369
95synaptic vesicle endocytosis (GO:0048488)3.06499022
96behavioral response to ethanol (GO:0048149)3.05025626
97organelle transport along microtubule (GO:0072384)3.04646834
98regulation of synapse assembly (GO:0051963)3.03150906
99response to auditory stimulus (GO:0010996)3.02947865
100membrane depolarization (GO:0051899)3.01640612
101regulation of excitatory postsynaptic membrane potential (GO:0060079)3.01208534
102regulation of respiratory system process (GO:0044065)3.00698554
103axon cargo transport (GO:0008088)3.00572172
104* regulation of neurotransmitter levels (GO:0001505)2.98328533
105membrane hyperpolarization (GO:0060081)2.98155623
106righting reflex (GO:0060013)2.97837342
107regulation of vesicle fusion (GO:0031338)2.97569845
108calcium ion-dependent exocytosis (GO:0017156)2.97232088
109synaptic transmission, cholinergic (GO:0007271)2.96869465
110short-term memory (GO:0007614)2.96636076
111protein polyglutamylation (GO:0018095)2.96143148
112startle response (GO:0001964)2.95982890
113epithelial cell differentiation involved in kidney development (GO:0035850)2.95577528
114dendrite morphogenesis (GO:0048813)2.94457043
115cerebellar granule cell differentiation (GO:0021707)2.92677599
116regulation of glutamate secretion (GO:0014048)2.92158476
117negative regulation of axonogenesis (GO:0050771)2.91709046
118ganglion development (GO:0061548)2.91572281
119regulation of cAMP-dependent protein kinase activity (GO:2000479)2.90690161
120dendrite development (GO:0016358)2.89614693
121epithelial cilium movement (GO:0003351)2.88456403
122positive regulation of membrane potential (GO:0045838)2.88359210
123neurofilament cytoskeleton organization (GO:0060052)2.88343860
124neuron migration (GO:0001764)2.88206884
125sequestering of actin monomers (GO:0042989)2.88043085
126positive regulation of synaptic transmission, glutamatergic (GO:0051968)2.87495743
127long-term memory (GO:0007616)2.86985785
128axonogenesis (GO:0007409)2.85511387
129positive regulation of dendritic spine development (GO:0060999)2.85270611
130innervation (GO:0060384)2.84652391
131neuron projection extension (GO:1990138)2.84247111
132adult walking behavior (GO:0007628)2.84048261
133positive regulation of growth hormone secretion (GO:0060124)2.83068851
134spinal cord development (GO:0021510)2.82496685
135positive regulation of amino acid transport (GO:0051957)2.82458858
136neuronal ion channel clustering (GO:0045161)2.81619353
137neuronal action potential (GO:0019228)2.80961930
138synapse organization (GO:0050808)2.80692300
139suckling behavior (GO:0001967)2.80420611
140synaptic transmission (GO:0007268)2.80067493
141calcium-mediated signaling using intracellular calcium source (GO:0035584)2.79829302
142negative regulation of amino acid transport (GO:0051956)2.78362387
143regulation of dendritic spine morphogenesis (GO:0061001)2.77498528
144regulation of extent of cell growth (GO:0061387)2.73119189
145adult behavior (GO:0030534)2.71427975
146nonmotile primary cilium assembly (GO:0035058)2.70435486
147neural tube formation (GO:0001841)2.70416615

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1EZH2_22144423_ChIP-Seq_EOC_Human6.50800201
2GBX2_23144817_ChIP-Seq_PC3_Human3.72653602
3RBPJ_22232070_ChIP-Seq_NCS_Mouse3.72314450
4HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse3.03044411
5JARID2_20064375_ChIP-Seq_MESCs_Mouse3.02608423
6* SUZ12_18692474_ChIP-Seq_MESCs_Mouse3.01887812
7SUZ12_18555785_ChIP-Seq_MESCs_Mouse2.95792031
8TAF15_26573619_Chip-Seq_HEK293_Human2.79480480
9* NR4A2_19515692_ChIP-ChIP_MN9D_Mouse2.74212384
10* REST_21632747_ChIP-Seq_MESCs_Mouse2.66959475
11RNF2_18974828_ChIP-Seq_MESCs_Mouse2.66715487
12EZH2_18974828_ChIP-Seq_MESCs_Mouse2.66715487
13JARID2_20075857_ChIP-Seq_MESCs_Mouse2.60262226
14EZH2_27304074_Chip-Seq_ESCs_Mouse2.57229318
15SUZ12_18974828_ChIP-Seq_MESCs_Mouse2.52825529
16* SUZ12_16625203_ChIP-ChIP_MESCs_Mouse2.48157020
17CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons2.41822464
18SUZ12_18692474_ChIP-Seq_MEFs_Mouse2.40210406
19* SUZ12_20075857_ChIP-Seq_MESCs_Mouse2.38334416
20* EED_16625203_ChIP-ChIP_MESCs_Mouse2.37209777
21MTF2_20144788_ChIP-Seq_MESCs_Mouse2.35938490
22GLI1_17442700_ChIP-ChIP_MESCs_Mouse2.31047728
23CTBP2_25329375_ChIP-Seq_LNCAP_Human2.20297349
24* SUZ12_27294783_Chip-Seq_ESCs_Mouse2.17988293
25* REST_18959480_ChIP-ChIP_MESCs_Mouse2.17361825
26EZH2_27294783_Chip-Seq_ESCs_Mouse2.16225938
27* RNF2_27304074_Chip-Seq_ESCs_Mouse2.05287167
28* BMI1_23680149_ChIP-Seq_NPCS_Mouse1.98197546
29DROSHA_22980978_ChIP-Seq_HELA_Human1.96015940
30AR_21572438_ChIP-Seq_LNCaP_Human1.94743736
31IKZF1_21737484_ChIP-ChIP_HCT116_Human1.90675208
32CTBP1_25329375_ChIP-Seq_LNCAP_Human1.89758971
33RARB_27405468_Chip-Seq_BRAIN_Mouse1.78437587
34ZFP57_27257070_Chip-Seq_ESCs_Mouse1.78377235
35SMAD4_21799915_ChIP-Seq_A2780_Human1.74278662
36ZNF274_21170338_ChIP-Seq_K562_Hela1.69828592
37CBX2_27304074_Chip-Seq_ESCs_Mouse1.64192831
38PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.62196736
39* P300_19829295_ChIP-Seq_ESCs_Human1.59637820
40IGF1R_20145208_ChIP-Seq_DFB_Human1.58751393
41* RNF2_27304074_Chip-Seq_NSC_Mouse1.54533477
42ZFP322A_24550733_ChIP-Seq_MESCs_Mouse1.49000086
43MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse1.47978072
44TOP2B_26459242_ChIP-Seq_MCF-7_Human1.47932711
45PHC1_16625203_ChIP-ChIP_MESCs_Mouse1.47801978
46* EWS_26573619_Chip-Seq_HEK293_Human1.47608076
47SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.40804938
48SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.39515456
49RNF2_16625203_ChIP-ChIP_MESCs_Mouse1.37121139
50ERG_21242973_ChIP-ChIP_JURKAT_Human1.36436025
51POU3F2_20337985_ChIP-ChIP_501MEL_Human1.33649104
52* SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.33039027
53NR3C1_23031785_ChIP-Seq_PC12_Mouse1.32573359
54SOX2_21211035_ChIP-Seq_LN229_Gbm1.32462481
55SMAD3_21741376_ChIP-Seq_EPCs_Human1.32420528
56* OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.30545156
57CEBPB_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.30435318
58MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human1.30015319
59* RING1B_27294783_Chip-Seq_ESCs_Mouse1.29126828
60KLF4_25985364_ChIP-Seq_ATHEROSCLEROSIS_LESION_Mouse1.27043100
61EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.26928218
62AR_25329375_ChIP-Seq_VCAP_Human1.26213643
63RCOR2_21632747_ChIP-Seq_MESCs_Mouse1.22925993
64PIAS1_25552417_ChIP-Seq_VCAP_Human1.22806612
65IRF1_19129219_ChIP-ChIP_H3396_Human1.22297287
66ESRRB_18555785_ChIP-Seq_MESCs_Mouse1.22044080
67MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human1.21878405
68SMAD_19615063_ChIP-ChIP_OVARY_Human1.20246704
69CDX2_19796622_ChIP-Seq_MESCs_Mouse1.19533830
70TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human1.16492457
71STAT3_23295773_ChIP-Seq_U87_Human1.16404228
72GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.16167750
73* UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human1.14763045
74* RCOR3_21632747_ChIP-Seq_MESCs_Mouse1.13934294
75MEIS1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse1.10939129
76AHR_22903824_ChIP-Seq_MCF-7_Human1.09593928
77TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.09078950
78TAL1_26923725_Chip-Seq_HPCs_Mouse1.08755039
79CBP_20019798_ChIP-Seq_JUKART_Human1.08516692
80IRF4_20064451_ChIP-Seq_CD4+T_Mouse1.08516692
81RUNX2_22187159_ChIP-Seq_PCA_Human1.08474931
82ARNT_22903824_ChIP-Seq_MCF-7_Human1.07934841
83P53_22127205_ChIP-Seq_FIBROBLAST_Human1.07271974
84* AR_19668381_ChIP-Seq_PC3_Human1.07127208
85VDR_22108803_ChIP-Seq_LS180_Human1.07046177
86ER_23166858_ChIP-Seq_MCF-7_Human1.06881381
87* RING1B_27294783_Chip-Seq_NPCs_Mouse1.04108790
88TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.03974510
89AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human1.03883011
90JUN_21703547_ChIP-Seq_K562_Human1.03607089
91SALL1_21062744_ChIP-ChIP_HESCs_Human1.03042401
92HOXD13_18407260_ChIP-ChIP_DEVELOPING-LIMBS_Mouse1.02565135
93* TCF4_23295773_ChIP-Seq_U87_Human1.02040170
94OLIG2_26023283_ChIP-Seq_AINV15_Mouse1.01785728
95BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse1.01576876
96EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse1.00478548
97TP53_22573176_ChIP-Seq_HFKS_Human0.98438733
98STAT3_24763339_ChIP-Seq_IMN-ESCs_Mouse0.97898934
99CEBPD_23245923_ChIP-Seq_MEFs_Mouse0.96113706
100PRDM14_20953172_ChIP-Seq_ESCs_Human0.95717574
101TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse0.95527281
102DNAJC2_21179169_ChIP-ChIP_NT2_Human0.95220494
103YAP1_20516196_ChIP-Seq_MESCs_Mouse0.95203190
104ETV2_25802403_ChIP-Seq_MESCs_Mouse0.95175432
105POU5F1_16153702_ChIP-ChIP_HESCs_Human0.94849024
106KLF5_20875108_ChIP-Seq_MESCs_Mouse0.94613540
107SOX9_26525672_Chip-Seq_HEART_Mouse0.94440266
108FUS_26573619_Chip-Seq_HEK293_Human0.93816618
109FOXP2_21765815_ChIP-ChIP_NEURO2A_Mouse0.93515426
110NANOG_18555785_Chip-Seq_ESCs_Mouse0.89974699
111POU5F1_26923725_Chip-Seq_MESODERM_Mouse0.89631524
112TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.89631524
113NR3C1_21868756_ChIP-Seq_MCF10A_Human0.89537356
114SMAD3_21741376_ChIP-Seq_ESCs_Human0.89007604
115CEBPB_26923725_Chip-Seq_MESODERM_Mouse0.88702652
116TP53_18474530_ChIP-ChIP_U2OS_Human0.88033330
117CRX_20693478_ChIP-Seq_ADULT_RETINA_Mouse0.87595930
118BCAT_22108803_ChIP-Seq_LS180_Human0.87109666
119LMO2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.85815487
120KDM2B_26808549_Chip-Seq_REH_Human0.85710465
121WT1_25993318_ChIP-Seq_PODOCYTE_Human0.85413732

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1* MP0003880_abnormal_central_pattern4.48453017
2MP0004859_abnormal_synaptic_plasticity4.14715597
3MP0001968_abnormal_touch/_nociception3.88592665
4* MP0003635_abnormal_synaptic_transmissio3.51084270
5MP0004270_analgesia3.41863599
6MP0005423_abnormal_somatic_nervous3.36441265
7* MP0006276_abnormal_autonomic_nervous3.23647660
8MP0002735_abnormal_chemical_nociception3.08666331
9MP0009046_muscle_twitch3.05257690
10MP0002734_abnormal_mechanical_nocicepti3.02374940
11MP0009745_abnormal_behavioral_response3.00895638
12MP0002736_abnormal_nociception_after2.94432546
13MP0002064_seizures2.93816085
14MP0001984_abnormal_olfaction2.83512071
15* MP0002063_abnormal_learning/memory/cond2.73151475
16MP0002733_abnormal_thermal_nociception2.61776485
17MP0002272_abnormal_nervous_system2.58540426
18MP0003122_maternal_imprinting2.57700575
19MP0002572_abnormal_emotion/affect_behav2.46496730
20MP0001440_abnormal_grooming_behavior2.43681670
21MP0001486_abnormal_startle_reflex2.34595465
22* MP0002067_abnormal_sensory_capabilities2.28193621
23* MP0001970_abnormal_pain_threshold2.27019462
24MP0002184_abnormal_innervation2.24726501
25MP0001501_abnormal_sleep_pattern2.21531960
26MP0000778_abnormal_nervous_system2.11227792
27MP0005645_abnormal_hypothalamus_physiol2.06261316
28MP0001529_abnormal_vocalization1.99610894
29MP0004142_abnormal_muscle_tone1.89838857
30MP0002102_abnormal_ear_morphology1.84940770
31MP0005386_behavior/neurological_phenoty1.79451181
32MP0004924_abnormal_behavior1.79451181
33MP0004858_abnormal_nervous_system1.77210764
34MP0002557_abnormal_social/conspecific_i1.76369887
35MP0003329_amyloid_beta_deposits1.75747175
36MP0005187_abnormal_penis_morphology1.72496861
37MP0004811_abnormal_neuron_physiology1.57905800
38MP0000955_abnormal_spinal_cord1.55577926
39MP0003890_abnormal_embryonic-extraembry1.54957294
40MP0005646_abnormal_pituitary_gland1.53435026
41MP0001502_abnormal_circadian_rhythm1.47526087
42MP0008569_lethality_at_weaning1.47215403
43MP0004133_heterotaxia1.46976498
44* MP0002882_abnormal_neuron_morphology1.46537986
45MP0003221_abnormal_cardiomyocyte_apopto1.46450380
46MP0004742_abnormal_vestibular_system1.43924061
47* MP0002066_abnormal_motor_capabilities/c1.38441351
48MP0002909_abnormal_adrenal_gland1.37719840
49MP0008877_abnormal_DNA_methylation1.30852296
50MP0005394_taste/olfaction_phenotype1.30762447
51MP0005499_abnormal_olfactory_system1.30762447
52MP0003787_abnormal_imprinting1.30721612
53MP0000751_myopathy1.29807159
54MP0002837_dystrophic_cardiac_calcinosis1.26238306
55MP0004145_abnormal_muscle_electrophysio1.24792975
56MP0001905_abnormal_dopamine_level1.23694108
57MP0010386_abnormal_urinary_bladder1.21320286
58MP0001986_abnormal_taste_sensitivity1.19910160
59MP0003121_genomic_imprinting1.12629560
60MP0001188_hyperpigmentation1.12370733
61MP0000647_abnormal_sebaceous_gland1.12101370
62MP0002229_neurodegeneration1.11759596
63MP0002928_abnormal_bile_duct1.10405748
64MP0008995_early_reproductive_senescence1.10068757
65MP0003283_abnormal_digestive_organ1.08496346
66MP0003879_abnormal_hair_cell1.07994718
67MP0005551_abnormal_eye_electrophysiolog1.06302337
68MP0009780_abnormal_chondrocyte_physiolo1.06246235
69MP0004885_abnormal_endolymph1.04961583
70* MP0002152_abnormal_brain_morphology1.04618392
71MP0002752_abnormal_somatic_nervous1.03805085
72MP0006072_abnormal_retinal_apoptosis0.97577677
73MP0002876_abnormal_thyroid_physiology0.94926243
74MP0005195_abnormal_posterior_eye0.94445181
75MP0003634_abnormal_glial_cell0.93857854
76MP0008872_abnormal_physiological_respon0.93853623
77* MP0003633_abnormal_nervous_system0.93531187
78MP0001963_abnormal_hearing_physiology0.92607153
79MP0002751_abnormal_autonomic_nervous0.91920615
80MP0003123_paternal_imprinting0.90248976
81MP0002653_abnormal_ependyma_morphology0.87878849
82MP0006292_abnormal_olfactory_placode0.87525586
83* MP0002069_abnormal_eating/drinking_beha0.84335199
84MP0000631_abnormal_neuroendocrine_gland0.83633684
85MP0001299_abnormal_eye_distance/0.81388061
86MP0005535_abnormal_body_temperature0.80533258
87MP0002234_abnormal_pharynx_morphology0.79940891
88* MP0003631_nervous_system_phenotype0.79839521
89MP0008789_abnormal_olfactory_epithelium0.79268342
90MP0002822_catalepsy0.76667283
91MP0005623_abnormal_meninges_morphology0.76542200
92MP0002638_abnormal_pupillary_reflex0.75722365
93MP0000604_amyloidosis0.75644175
94MP0004085_abnormal_heartbeat0.74624752
95MP0003119_abnormal_digestive_system0.74214868
96MP0001485_abnormal_pinna_reflex0.73884750
97MP0005391_vision/eye_phenotype0.73540945
98MP0000920_abnormal_myelination0.68887021
99MP0003315_abnormal_perineum_morphology0.67666574
100MP0003137_abnormal_impulse_conducting0.67658548
101MP0005253_abnormal_eye_physiology0.67558574
102MP0000538_abnormal_urinary_bladder0.66478909
103* MP0002081_perinatal_lethality0.65671385
104* MP0001943_abnormal_respiration0.64120523
105MP0003690_abnormal_glial_cell0.63750204
106MP0002160_abnormal_reproductive_system0.61563020
107MP0000026_abnormal_inner_ear0.61464472
108MP0003567_abnormal_fetal_cardiomyocyte0.60199213
109MP0001324_abnormal_eye_pigmentation0.59813018
110MP0003861_abnormal_nervous_system0.59434827
111MP0005379_endocrine/exocrine_gland_phen0.59259836
112MP0000569_abnormal_digit_pigmentation0.57682552
113* MP0010769_abnormal_survival0.57198951
114MP0003632_abnormal_nervous_system0.57080906
115MP0001664_abnormal_digestion0.56861826
116* MP0010770_preweaning_lethality0.55965661
117* MP0002082_postnatal_lethality0.55965661
118MP0002163_abnormal_gland_morphology0.55934287
119MP0005367_renal/urinary_system_phenotyp0.55783361
120MP0000516_abnormal_urinary_system0.55783361
121MP0006035_abnormal_mitochondrial_morpho0.54807045
122MP0001348_abnormal_lacrimal_gland0.54148366
123MP0004215_abnormal_myocardial_fiber0.54115535

Predicted human phenotypes

RankGene SetZ-score
1Focal motor seizures (HP:0011153)6.82239651
2Focal seizures (HP:0007359)5.38988587
3Myokymia (HP:0002411)5.13742493
4Atonic seizures (HP:0010819)5.12627348
5Febrile seizures (HP:0002373)4.57127600
6Visual hallucinations (HP:0002367)4.47366840
7Supranuclear gaze palsy (HP:0000605)4.42743603
8Absence seizures (HP:0002121)4.27334334
9Epileptic encephalopathy (HP:0200134)3.96354751
10Cortical dysplasia (HP:0002539)3.92344725
11Progressive cerebellar ataxia (HP:0002073)3.91400337
12Dialeptic seizures (HP:0011146)3.88414000
13Generalized tonic-clonic seizures (HP:0002069)3.75094875
14Polyphagia (HP:0002591)3.66846487
15Lissencephaly (HP:0001339)3.65642070
16Abnormal eating behavior (HP:0100738)3.54475660
17Failure to thrive in infancy (HP:0001531)3.46242819
18Ankle clonus (HP:0011448)3.35236270
19Pheochromocytoma (HP:0002666)3.18251721
20Broad-based gait (HP:0002136)3.15630728
21Termporal pattern (HP:0011008)3.15500846
22Insidious onset (HP:0003587)3.15500846
23Progressive inability to walk (HP:0002505)3.09321182
24Pachygyria (HP:0001302)3.02394598
25Action tremor (HP:0002345)3.00724474
26Retinal dysplasia (HP:0007973)2.97461141
27Mutism (HP:0002300)2.95758169
28Hyperventilation (HP:0002883)2.92348447
29Truncal ataxia (HP:0002078)2.92214720
30Abnormality of the corticospinal tract (HP:0002492)2.88354610
31Gait imbalance (HP:0002141)2.87624501
32Neuroendocrine neoplasm (HP:0100634)2.84382064
33Pancreatic fibrosis (HP:0100732)2.79640027
34Agitation (HP:0000713)2.76265439
35Excessive salivation (HP:0003781)2.76137613
36Drooling (HP:0002307)2.76137613
37True hermaphroditism (HP:0010459)2.71896718
38Neurofibrillary tangles (HP:0002185)2.70652241
39Spastic gait (HP:0002064)2.70473068
40Abnormal hair whorl (HP:0010721)2.70449456
41Urinary urgency (HP:0000012)2.68783013
42Limb dystonia (HP:0002451)2.68631172
43Urinary bladder sphincter dysfunction (HP:0002839)2.68347834
44Amblyopia (HP:0000646)2.66227480
45Pancreatic cysts (HP:0001737)2.65085299
46Esotropia (HP:0000565)2.62844747
47Depression (HP:0000716)2.61308450
48Abnormal ciliary motility (HP:0012262)2.60636620
49Hypoventilation (HP:0002791)2.59339822
50Anxiety (HP:0000739)2.57570706
51Ulnar claw (HP:0001178)2.57567303
52Wrist flexion contracture (HP:0001239)2.55213355
53Hemiparesis (HP:0001269)2.51349060
54Hypothermia (HP:0002045)2.51134453
55Specific learning disability (HP:0001328)2.48447711
56Impaired vibration sensation in the lower limbs (HP:0002166)2.48196453
57Polymicrogyria (HP:0002126)2.44636776
58Molar tooth sign on MRI (HP:0002419)2.43164149
59Abnormality of midbrain morphology (HP:0002418)2.43164149
60Nephronophthisis (HP:0000090)2.42531184
61Dysdiadochokinesis (HP:0002075)2.41558430
62Absent speech (HP:0001344)2.38209667
63Congenital primary aphakia (HP:0007707)2.36739053
64Cerebral inclusion bodies (HP:0100314)2.36044062
65Fetal akinesia sequence (HP:0001989)2.33133292
66Spastic tetraplegia (HP:0002510)2.32467910
67Papilledema (HP:0001085)2.31020603
68Dysmetria (HP:0001310)2.30798314
69Lower limb muscle weakness (HP:0007340)2.30486743
70Scanning speech (HP:0002168)2.30019515
71Respiratory insufficiency due to defective ciliary clearance (HP:0200073)2.29041058
72Hypoplasia of the brainstem (HP:0002365)2.26284797
73Aplasia/Hypoplasia of the brainstem (HP:0007362)2.26284797
74Abnormal respiratory motile cilium physiology (HP:0012261)2.25208050
75Poor suck (HP:0002033)2.22917029
76Medial flaring of the eyebrow (HP:0010747)2.22913251
77Abnormality of the labia minora (HP:0012880)2.22090835
78Abnormal respiratory motile cilium morphology (HP:0005938)2.20829750
79Abnormal respiratory epithelium morphology (HP:0012253)2.20829750
80Abnormality of pain sensation (HP:0010832)2.20682352
81Impaired pain sensation (HP:0007328)2.20682352
82Muscular hypotonia of the trunk (HP:0008936)2.20664870
83Genetic anticipation (HP:0003743)2.20571120
84Degeneration of the lateral corticospinal tracts (HP:0002314)2.20500693
85Atrophy/Degeneration involving the corticospinal tracts (HP:0007372)2.20500693
86Psychosis (HP:0000709)2.19879370
87Poor coordination (HP:0002370)2.18857698
88Exotropia (HP:0000577)2.18469776
89Insomnia (HP:0100785)2.17534340
90Amyotrophic lateral sclerosis (HP:0007354)2.16907484
91Hyperthyroidism (HP:0000836)2.15791823
92Nephrogenic diabetes insipidus (HP:0009806)2.13483185
93Peripheral hypomyelination (HP:0007182)2.13292664
94Postural instability (HP:0002172)2.12991123
95Inability to walk (HP:0002540)2.12755808
96Protruding tongue (HP:0010808)2.12013137
97Chronic hepatic failure (HP:0100626)2.10957970
98Poor eye contact (HP:0000817)2.10607398
99Akinesia (HP:0002304)2.10085940
100Gaze-evoked nystagmus (HP:0000640)2.08098097
101Genital tract atresia (HP:0001827)2.07009389
102Epileptiform EEG discharges (HP:0011182)2.06956623
103Type II lissencephaly (HP:0007260)2.06842302
104EEG with generalized epileptiform discharges (HP:0011198)2.04217557
105Narrow nasal bridge (HP:0000446)2.04186988
106Ventricular fibrillation (HP:0001663)2.03892385
107Vaginal atresia (HP:0000148)2.03667450
108Impaired social interactions (HP:0000735)2.02284061
109Abnormal social behavior (HP:0012433)2.02284061
110Abnormality of the renal medulla (HP:0100957)2.01979171
111Abnormality of binocular vision (HP:0011514)1.98475189
112Diplopia (HP:0000651)1.98475189
113Abnormality of the lower motor neuron (HP:0002366)1.96401231
114Abnormality of the vocal cords (HP:0008777)1.96014906
115Bradykinesia (HP:0002067)1.94897908
116Neoplasm of the heart (HP:0100544)1.94519431
117Decreased number of large peripheral myelinated nerve fibers (HP:0003387)1.94328835
118Generalized hypotonia (HP:0001290)1.93881539
119Abnormality of salivation (HP:0100755)1.93876653
120Torticollis (HP:0000473)1.93633509
121Shoulder girdle muscle weakness (HP:0003547)1.93318305
122Abnormality of the hip-girdle musculature (HP:0001445)1.91521769
123Abnormality of the musculature of the pelvis (HP:0001469)1.91521769
124Broad foot (HP:0001769)1.91179866
125Anosmia (HP:0000458)1.91008483
126Morphological abnormality of the pyramidal tract (HP:0002062)1.90594655
127Narrow forehead (HP:0000341)1.89472010
128Hypsarrhythmia (HP:0002521)1.89357460
129Postaxial hand polydactyly (HP:0001162)1.85626352
130Decreased testicular size (HP:0008734)1.85497159
131Hip dysplasia (HP:0001385)1.85424561
132Hypoplasia of the corpus callosum (HP:0002079)1.83999706
133Anencephaly (HP:0002323)1.83316450
134Intention tremor (HP:0002080)1.81122988
135Hyperglycinemia (HP:0002154)1.79995865
136Cystic liver disease (HP:0006706)1.79523754
137Aplasia/Hypoplasia of the lens (HP:0008063)1.78718174
138Tubulointerstitial abnormality (HP:0001969)1.77273051
139Occipital encephalocele (HP:0002085)1.76186906
140Status epilepticus (HP:0002133)1.73931112
141Atrophy/Degeneration involving motor neurons (HP:0007373)1.73101924
142Cerebellar dysplasia (HP:0007033)1.71676263
143Inappropriate behavior (HP:0000719)1.71472734
144Aplasia/Hypoplasia of the tongue (HP:0010295)1.70846112

Predicted kinase interactions (KEA)

RankGene SetZ-score
1NTRK33.98016680
2MARK13.73952576
3CASK3.66501915
4MAP3K93.42402975
5MAP3K123.40201399
6TRIM283.35492040
7MAP3K43.20603227
8MINK12.99660538
9MAP2K72.81372280
10NTRK22.54590606
11PNCK2.40763053
12EPHA32.32732065
13MAP2K42.19671575
14TNIK2.16345548
15NTRK12.06581423
16PAK61.95214877
17MAPK131.94409799
18UHMK11.79212902
19DYRK31.70755679
20SIK21.64309046
21CDK191.58786021
22PHKG21.56616195
23PHKG11.56616195
24EPHA41.56456571
25DAPK21.51010367
26MAP4K21.48010558
27ARAF1.47322305
28GRK51.47080485
29KSR11.43239331
30EPHB11.43145273
31MAP3K61.40742482
32PINK11.40099758
33CDK51.38573141
34KSR21.31794521
35GRK71.26730467
36LATS21.26289833
37DYRK1B1.25274007
38PLK21.22361325
39PAK31.22054077
40RIPK41.20770095
41LIMK11.15452121
42LMTK21.14597294
43PRKCG1.09319682
44SIK31.09236199
45BCR1.08164080
46OXSR11.03814997
47RPS6KA41.00817880
48BCKDK1.00279183
49SGK4940.98693160
50SGK2230.98693160
51CAMK2A0.98503187
52CAMKK20.95852804
53FES0.95462971
54CSNK1G10.95318580
55CAMKK10.94409469
56WNK30.93091957
57CSNK1G20.90771030
58CDK140.90431077
59FRK0.89507368
60CDK180.87530297
61TNK20.84470217
62CDK150.80627937
63DAPK10.79977735
64ADRBK20.79290738
65FER0.78852040
66STK390.76122759
67BMPR1B0.75653119
68CAMK1G0.75597325
69STK380.75564724
70DYRK20.74806663
71RET0.74144402
72CAMK2B0.73787144
73WNK10.71669202
74ERBB30.69364367
75ADRBK10.68824497
76CDK11A0.68308369
77SGK20.68291068
78TYRO30.66833873
79CSNK1G30.66141355
80ROCK20.64665452
81CAMK2D0.63805603
82CAMK40.63621722
83NME10.61543738
84STK110.60226359
85DYRK1A0.58864263
86PRKCE0.58513051
87CDC42BPA0.58472731
88RPS6KA20.58285285
89SRPK10.57456855
90CAMK2G0.56223899
91CSNK1A1L0.53398188
92PRKCH0.52586144
93MAP3K20.52208725
94WNK40.51551835
95IRAK20.51355518
96PRKCZ0.50325987
97PKN20.46311742
98CAMK10.45854975
99SGK10.45155401
100MAPK100.43865215
101BRAF0.42089407
102PRKAA10.41496901
103GRK10.41224789
104ROCK10.39237870
105MAP3K50.37905298
106RPS6KA30.37537268
107FGFR20.37168843
108SGK30.36940162
109PRKACA0.36387549
110PRKCB0.35156454
111MAPK90.34702807
112MAP2K10.34553929
113MARK20.33675637
114CSNK1E0.33504419
115FYN0.33347710
116CSNK1D0.32205401
117PRKG10.32108228
118MAPK150.31289871
119ERBB20.31063752
120PRKACB0.30871123
121AKT30.30814121
122INSRR0.30662165
123PKN10.30531137
124EPHB20.30195330
125MAPK40.27500966
126MKNK20.25817278
127CSNK1A10.23334170
128VRK10.22673081
129YES10.22181585
130PRKACG0.21742159
131EGFR0.20517293

Predicted pathways (KEGG)

RankGene SetZ-score
1* Nicotine addiction_Homo sapiens_hsa050333.94802401
2* Synaptic vesicle cycle_Homo sapiens_hsa047213.39172821
3Butirosin and neomycin biosynthesis_Homo sapiens_hsa005243.15918217
4Olfactory transduction_Homo sapiens_hsa047403.01987128
5GABAergic synapse_Homo sapiens_hsa047272.82877243
6* Retrograde endocannabinoid signaling_Homo sapiens_hsa047232.58990314
7Taste transduction_Homo sapiens_hsa047422.42298244
8Morphine addiction_Homo sapiens_hsa050322.38590549
9Circadian entrainment_Homo sapiens_hsa047132.30844578
10Vasopressin-regulated water reabsorption_Homo sapiens_hsa049622.30219100
11Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049612.20152622
12Long-term potentiation_Homo sapiens_hsa047202.17072536
13Collecting duct acid secretion_Homo sapiens_hsa049662.16165515
14* Glutamatergic synapse_Homo sapiens_hsa047242.11952797
15Dopaminergic synapse_Homo sapiens_hsa047282.06950871
16Oxidative phosphorylation_Homo sapiens_hsa001901.98556448
17Insulin secretion_Homo sapiens_hsa049111.94268279
18Amphetamine addiction_Homo sapiens_hsa050311.88682969
19Serotonergic synapse_Homo sapiens_hsa047261.81725402
20Salivary secretion_Homo sapiens_hsa049701.78907943
21Cardiac muscle contraction_Homo sapiens_hsa042601.76426445
22Pathogenic Escherichia coli infection_Homo sapiens_hsa051301.69745759
23Renin secretion_Homo sapiens_hsa049241.67927336
24Gastric acid secretion_Homo sapiens_hsa049711.66084066
25Maturity onset diabetes of the young_Homo sapiens_hsa049501.65453246
26Cholinergic synapse_Homo sapiens_hsa047251.61734530
27Parkinsons disease_Homo sapiens_hsa050121.59128680
28Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042611.53605863
29Long-term depression_Homo sapiens_hsa047301.52464920
30Cocaine addiction_Homo sapiens_hsa050301.50301635
31Vibrio cholerae infection_Homo sapiens_hsa051101.48302135
32Alzheimers disease_Homo sapiens_hsa050101.47541215
33Aldosterone synthesis and secretion_Homo sapiens_hsa049251.42442948
34Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047501.42153835
35Neuroactive ligand-receptor interaction_Homo sapiens_hsa040801.40923104
36Axon guidance_Homo sapiens_hsa043601.37193998
37Gap junction_Homo sapiens_hsa045401.37174817
38Oxytocin signaling pathway_Homo sapiens_hsa049211.36054059
39Calcium signaling pathway_Homo sapiens_hsa040201.34922884
40GnRH signaling pathway_Homo sapiens_hsa049121.31508095
41Protein export_Homo sapiens_hsa030601.29720452
42Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049641.26246631
43Phototransduction_Homo sapiens_hsa047441.26122994
44Steroid biosynthesis_Homo sapiens_hsa001001.23645617
45Huntingtons disease_Homo sapiens_hsa050161.17266770
46Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010401.15728685
47Estrogen signaling pathway_Homo sapiens_hsa049151.13407534
48Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005341.12297024
49Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051201.07535896
50cAMP signaling pathway_Homo sapiens_hsa040241.07015825
51Melanogenesis_Homo sapiens_hsa049161.02926115
52Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.96272240
53Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.95381802
54ErbB signaling pathway_Homo sapiens_hsa040120.90688046
55Butanoate metabolism_Homo sapiens_hsa006500.89522680
56Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049600.88487949
57Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001300.88276575
58Oocyte meiosis_Homo sapiens_hsa041140.87100643
59Type II diabetes mellitus_Homo sapiens_hsa049300.86936186
60Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.84758297
61Dorso-ventral axis formation_Homo sapiens_hsa043200.82909439
62Ether lipid metabolism_Homo sapiens_hsa005650.80623664
63Phosphatidylinositol signaling system_Homo sapiens_hsa040700.80227790
64Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.78133988
65Glioma_Homo sapiens_hsa052140.74490836
66Synthesis and degradation of ketone bodies_Homo sapiens_hsa000720.73801092
67Vascular smooth muscle contraction_Homo sapiens_hsa042700.73101449
68Linoleic acid metabolism_Homo sapiens_hsa005910.69637436
69cGMP-PKG signaling pathway_Homo sapiens_hsa040220.68995077
70Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.68905226
71alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.67055086
72Thyroid hormone synthesis_Homo sapiens_hsa049180.64531471
73Dilated cardiomyopathy_Homo sapiens_hsa054140.63170077
74Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.62980724
75MAPK signaling pathway_Homo sapiens_hsa040100.62936516
76Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.62115518
77Pancreatic secretion_Homo sapiens_hsa049720.62106650
78Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049320.60813968
79Neurotrophin signaling pathway_Homo sapiens_hsa047220.58746628
80Phospholipase D signaling pathway_Homo sapiens_hsa040720.58299651
81SNARE interactions in vesicular transport_Homo sapiens_hsa041300.58246008
82Phagosome_Homo sapiens_hsa041450.55666042
83Hedgehog signaling pathway_Homo sapiens_hsa043400.54563679
84Fatty acid metabolism_Homo sapiens_hsa012120.54249769
85Alcoholism_Homo sapiens_hsa050340.53366150
86Prion diseases_Homo sapiens_hsa050200.52759036
87Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.50307587
88Hippo signaling pathway_Homo sapiens_hsa043900.50222468
89Fatty acid elongation_Homo sapiens_hsa000620.47358628
90Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054120.46905303
91Rheumatoid arthritis_Homo sapiens_hsa053230.46426246
92Insulin signaling pathway_Homo sapiens_hsa049100.45628960
93Ras signaling pathway_Homo sapiens_hsa040140.45303586
94Glucagon signaling pathway_Homo sapiens_hsa049220.45220191
95Choline metabolism in cancer_Homo sapiens_hsa052310.44697400
96Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054100.44270443
97Basal transcription factors_Homo sapiens_hsa030220.43427913
98Bile secretion_Homo sapiens_hsa049760.43072589
99Wnt signaling pathway_Homo sapiens_hsa043100.41211382
100Starch and sucrose metabolism_Homo sapiens_hsa005000.40705232
101Renal cell carcinoma_Homo sapiens_hsa052110.40466000
102Endometrial cancer_Homo sapiens_hsa052130.38853432
103Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.38564553
104Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.38476245
105Salmonella infection_Homo sapiens_hsa051320.38403510
106Ovarian steroidogenesis_Homo sapiens_hsa049130.37908036
107Basal cell carcinoma_Homo sapiens_hsa052170.37867246
108Tryptophan metabolism_Homo sapiens_hsa003800.37576431
109Tight junction_Homo sapiens_hsa045300.37548045
110Taurine and hypotaurine metabolism_Homo sapiens_hsa004300.37107328
111Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.36876489
112Sphingolipid signaling pathway_Homo sapiens_hsa040710.36294444
113Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.35431165
114Prolactin signaling pathway_Homo sapiens_hsa049170.34692282
115VEGF signaling pathway_Homo sapiens_hsa043700.32980160
116Fatty acid biosynthesis_Homo sapiens_hsa000610.31991216
117Inositol phosphate metabolism_Homo sapiens_hsa005620.31803672
118Endocytosis_Homo sapiens_hsa041440.31671825
119Carbohydrate digestion and absorption_Homo sapiens_hsa049730.31382692
120AMPK signaling pathway_Homo sapiens_hsa041520.31057107
121Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.30487782
122Rap1 signaling pathway_Homo sapiens_hsa040150.30365097
123RNA degradation_Homo sapiens_hsa030180.30221604
124Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.29526799
125Circadian rhythm_Homo sapiens_hsa047100.29512922
126Glycerophospholipid metabolism_Homo sapiens_hsa005640.28400684
127Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004000.28120854
128Colorectal cancer_Homo sapiens_hsa052100.27700077
129Thyroid hormone signaling pathway_Homo sapiens_hsa049190.27697947
130Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.27016531
131Regulation of autophagy_Homo sapiens_hsa041400.25802727

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