SLC16A14

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1vocalization behavior (GO:0071625)5.36548459
2desmosome organization (GO:0002934)4.89791785
3neuron cell-cell adhesion (GO:0007158)4.86561901
4regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor act4.76946826
5protein localization to synapse (GO:0035418)4.53011961
6pyrimidine nucleobase catabolic process (GO:0006208)4.48751680
7exploration behavior (GO:0035640)4.43830266
8regulation of glutamate receptor signaling pathway (GO:1900449)4.38113786
9regulation of short-term neuronal synaptic plasticity (GO:0048172)4.33765126
10positive regulation of mitochondrial fission (GO:0090141)4.31059479
11glutamate secretion (GO:0014047)4.30225962
12positive regulation of action potential (GO:0045760)4.26080922
13positive regulation of excitatory postsynaptic membrane potential (GO:2000463)4.17291438
14synaptic vesicle exocytosis (GO:0016079)4.15969280
15dendritic spine morphogenesis (GO:0060997)4.15592617
16locomotory exploration behavior (GO:0035641)4.08546585
17regulation of N-methyl-D-aspartate selective glutamate receptor activity (GO:2000310)3.95683957
18keratinocyte proliferation (GO:0043616)3.91289603
19establishment of mitochondrion localization (GO:0051654)3.86736522
20positive regulation of calcium ion-dependent exocytosis (GO:0045956)3.84211507
21neuron recognition (GO:0008038)3.81158746
22neurotransmitter-gated ion channel clustering (GO:0072578)3.76215072
23nucleobase catabolic process (GO:0046113)3.76001054
24positive regulation of vesicle fusion (GO:0031340)3.73274720
25layer formation in cerebral cortex (GO:0021819)3.73007298
26tachykinin receptor signaling pathway (GO:0007217)3.72474199
27ionotropic glutamate receptor signaling pathway (GO:0035235)3.70499064
28synaptic vesicle maturation (GO:0016188)3.70416310
29negative regulation of synaptic transmission, glutamatergic (GO:0051967)3.65129972
30axonal fasciculation (GO:0007413)3.64588005
31neuronal action potential propagation (GO:0019227)3.63004060
32glutamate receptor signaling pathway (GO:0007215)3.62266907
33positive regulation of synapse maturation (GO:0090129)3.59627384
34calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules (GO:0016339)3.57359694
35postsynaptic membrane organization (GO:0001941)3.54019812
36protein localization to cilium (GO:0061512)3.51057022
37negative regulation of synaptic transmission, GABAergic (GO:0032229)3.47534237
38regulation of vesicle fusion (GO:0031338)3.46771636
39retinal ganglion cell axon guidance (GO:0031290)3.46411220
40cochlea development (GO:0090102)3.42492331
41regulation of long-term neuronal synaptic plasticity (GO:0048169)3.41807609
42regulation of synaptic vesicle exocytosis (GO:2000300)3.39786901
43neurotransmitter secretion (GO:0007269)3.39554779
44presynaptic membrane assembly (GO:0097105)3.33768456
45innervation (GO:0060384)3.26980524
46transmission of nerve impulse (GO:0019226)3.24144562
47exogenous drug catabolic process (GO:0042738)3.22578132
48neuron-neuron synaptic transmission (GO:0007270)3.22142626
49positive regulation of membrane potential (GO:0045838)3.13649465
50neuronal ion channel clustering (GO:0045161)3.13632135
51regulation of action potential (GO:0098900)3.13193676
52regulation of neuronal synaptic plasticity (GO:0048168)3.11701442
53auditory behavior (GO:0031223)3.10712296
54G-protein coupled glutamate receptor signaling pathway (GO:0007216)3.10147928
55negative regulation of heart rate (GO:0010459)3.09158087
56chemosensory behavior (GO:0007635)3.09092988
57regulation of synapse structural plasticity (GO:0051823)3.09031315
58glycosphingolipid biosynthetic process (GO:0006688)3.08474673
59hippocampus development (GO:0021766)3.08398210
60cell migration in hindbrain (GO:0021535)3.07937188
61synaptic transmission, glutamatergic (GO:0035249)3.06564167
62cerebral cortex radially oriented cell migration (GO:0021799)3.06441104
63regulation of glucocorticoid secretion (GO:2000849)3.05317210
64regulation of dendritic spine morphogenesis (GO:0061001)3.05075645
65negative regulation of keratinocyte proliferation (GO:0010839)3.02798561
66regulation of synaptic vesicle transport (GO:1902803)3.01697811
67response to histamine (GO:0034776)3.01543617
68negative regulation of microtubule polymerization (GO:0031115)3.01362420
69mitochondrial outer membrane permeabilization involved in programmed cell death (GO:1902686)3.00898394
70positive regulation of mitochondrial membrane permeability involved in apoptotic process (GO:19021103.00898394
71gamma-aminobutyric acid signaling pathway (GO:0007214)3.00510384
72intraciliary transport (GO:0042073)2.99692488
73central nervous system projection neuron axonogenesis (GO:0021952)2.99413076
74cellular potassium ion homeostasis (GO:0030007)2.99164527
75proline transport (GO:0015824)2.99091455
76glucosamine-containing compound catabolic process (GO:1901072)2.98301998
77positive regulation of synaptic transmission, GABAergic (GO:0032230)2.98013099
78positive regulation of synapse assembly (GO:0051965)2.97748901
79dendritic spine organization (GO:0097061)2.97647818
80ephrin receptor signaling pathway (GO:0048013)2.97543991
81presynaptic membrane organization (GO:0097090)2.96332171
82nonmotile primary cilium assembly (GO:0035058)2.95518826
83cellular response to ammonium ion (GO:0071242)2.94997650
84neurotransmitter transport (GO:0006836)2.94434624
85gamma-aminobutyric acid transport (GO:0015812)2.94263860
86negative regulation of oligodendrocyte differentiation (GO:0048715)2.93801996
87synapse assembly (GO:0007416)2.92454350
88positive regulation of potassium ion transmembrane transporter activity (GO:1901018)2.92362015
89olfactory bulb development (GO:0021772)2.91913460
90regulation of excitatory postsynaptic membrane potential (GO:0060079)2.91639818
91regulation of dendritic spine development (GO:0060998)2.90797358
92regulation of respiratory gaseous exchange by neurological system process (GO:0002087)2.87955417
93cerebellar Purkinje cell differentiation (GO:0021702)2.85315226
94regulation of feeding behavior (GO:0060259)2.84543835
95establishment of skin barrier (GO:0061436)2.83832116
96ATP hydrolysis coupled proton transport (GO:0015991)2.82929988
97energy coupled proton transmembrane transport, against electrochemical gradient (GO:0015988)2.82929988
98regulation of postsynaptic membrane potential (GO:0060078)2.82415121
99mechanosensory behavior (GO:0007638)2.81287440
100neural tube formation (GO:0001841)2.79661461
101organelle transport along microtubule (GO:0072384)2.79656174
102sequestering of actin monomers (GO:0042989)2.79541824
103central nervous system neuron axonogenesis (GO:0021955)2.79503647
104negative regulation of dendrite development (GO:2000171)2.79020650
105regulation of mitochondrial fission (GO:0090140)2.78126710
106cullin deneddylation (GO:0010388)2.77158143
107intraspecies interaction between organisms (GO:0051703)2.75491122
108social behavior (GO:0035176)2.75491122
109response to auditory stimulus (GO:0010996)2.75033190
110drug catabolic process (GO:0042737)2.74433130
111long-term synaptic potentiation (GO:0060291)2.73981119
112dendrite morphogenesis (GO:0048813)2.73079369
113neurofilament cytoskeleton organization (GO:0060052)2.73040646
114regulation of synaptic transmission, GABAergic (GO:0032228)2.72741150
115acidic amino acid transport (GO:0015800)2.71588808
116positive regulation of dendritic spine morphogenesis (GO:0061003)2.71449702
117establishment of mitochondrion localization, microtubule-mediated (GO:0034643)2.71276815
118mitochondrion transport along microtubule (GO:0047497)2.71276815
119cytoskeleton-dependent intracellular transport (GO:0030705)2.71084627
120long-term memory (GO:0007616)2.70681896
121short-term memory (GO:0007614)2.69711949
122synaptic vesicle endocytosis (GO:0048488)2.69181830
123heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules (GO:0007157)2.69160354
124aminoglycoside antibiotic metabolic process (GO:0030647)2.67956864
125keratinocyte development (GO:0003334)2.67222917
126C4-dicarboxylate transport (GO:0015740)2.66999765
127nonribosomal peptide biosynthetic process (GO:0019184)2.66788570
128regulation of synaptic plasticity (GO:0048167)2.66666145
129regulation of inhibitory postsynaptic membrane potential (GO:0060080)2.66511095
130behavioral response to cocaine (GO:0048148)2.66468511
131axon extension (GO:0048675)2.66195268
132cerebellar granule cell differentiation (GO:0021707)2.66163862
133serotonin metabolic process (GO:0042428)2.65694882
134behavioral response to nicotine (GO:0035095)2.65442117
135establishment of vesicle localization (GO:0051650)2.64999916
136glutathione biosynthetic process (GO:0006750)2.64926600
137behavioral fear response (GO:0001662)2.64683844
138behavioral defense response (GO:0002209)2.64683844
139synaptic vesicle transport (GO:0048489)2.64681677
140establishment of synaptic vesicle localization (GO:0097480)2.64681677
141regulation of synapse maturation (GO:0090128)2.64557876
142regulation of synaptic transmission, glutamatergic (GO:0051966)2.64192024
143synapse organization (GO:0050808)2.63894334
144homophilic cell adhesion via plasma membrane adhesion molecules (GO:0007156)2.63281855
145regulation of ruffle assembly (GO:1900027)2.63174756
146regulation of neurotransmitter levels (GO:0001505)2.61994791
147spinal cord development (GO:0021510)2.61915866
148regulation of phospholipase A2 activity (GO:0032429)2.61790194
149learning (GO:0007612)2.60984878
150microtubule-based transport (GO:0010970)2.60842914
151limb bud formation (GO:0060174)2.60810518
152organic cation transport (GO:0015695)2.60056231
153startle response (GO:0001964)2.58575538
154somite development (GO:0061053)2.58207880

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1EZH2_22144423_ChIP-Seq_EOC_Human5.17155142
2TP63_17297297_ChIP-ChIP_HaCaT_Human3.94129450
3GBX2_23144817_ChIP-Seq_PC3_Human3.49761935
4JARID2_20064375_ChIP-Seq_MESCs_Mouse3.08883577
5* SUZ12_18692474_ChIP-Seq_MESCs_Mouse3.03759116
6SUZ12_18555785_ChIP-Seq_MESCs_Mouse2.99681804
7EZH2_27304074_Chip-Seq_ESCs_Mouse2.89049163
8* SUZ12_18974828_ChIP-Seq_MESCs_Mouse2.71675389
9SUZ12_16625203_ChIP-ChIP_MESCs_Mouse2.67496561
10EZH2_18974828_ChIP-Seq_MESCs_Mouse2.63115950
11RNF2_18974828_ChIP-Seq_MESCs_Mouse2.63115950
12JARID2_20075857_ChIP-Seq_MESCs_Mouse2.61891729
13* SUZ12_18692474_ChIP-Seq_MEFs_Mouse2.54321851
14EED_16625203_ChIP-ChIP_MESCs_Mouse2.50368041
15RBPJ_22232070_ChIP-Seq_NCS_Mouse2.44296762
16TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse2.40355849
17* SUZ12_27294783_Chip-Seq_ESCs_Mouse2.38160339
18* SUZ12_20075857_ChIP-Seq_MESCs_Mouse2.28349559
19* MTF2_20144788_ChIP-Seq_MESCs_Mouse2.28164340
20* EZH2_27294783_Chip-Seq_ESCs_Mouse2.24355705
21SALL1_21062744_ChIP-ChIP_HESCs_Human2.23530812
22GLI1_17442700_ChIP-ChIP_MESCs_Mouse2.17838236
23RNF2_27304074_Chip-Seq_ESCs_Mouse2.10199153
24TAF15_26573619_Chip-Seq_HEK293_Human2.06560342
25REST_21632747_ChIP-Seq_MESCs_Mouse2.05182747
26AR_21572438_ChIP-Seq_LNCaP_Human2.01516814
27CTBP1_25329375_ChIP-Seq_LNCAP_Human1.91859209
28BMI1_23680149_ChIP-Seq_NPCS_Mouse1.91492660
29CTBP2_25329375_ChIP-Seq_LNCAP_Human1.88279427
30ZFP57_27257070_Chip-Seq_ESCs_Mouse1.88056907
31CBX2_27304074_Chip-Seq_ESCs_Mouse1.80815079
32DROSHA_22980978_ChIP-Seq_HELA_Human1.78077928
33EWS_26573619_Chip-Seq_HEK293_Human1.76748221
34PHC1_16625203_ChIP-ChIP_MESCs_Mouse1.75420105
35GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.73205379
36HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse1.69072071
37RNF2_16625203_ChIP-ChIP_MESCs_Mouse1.67477883
38NR4A2_19515692_ChIP-ChIP_MN9D_Mouse1.66440004
39* REST_18959480_ChIP-ChIP_MESCs_Mouse1.63859427
40RNF2_27304074_Chip-Seq_NSC_Mouse1.60103465
41* HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human1.58765897
42P300_19829295_ChIP-Seq_ESCs_Human1.55605213
43ERG_21242973_ChIP-ChIP_JURKAT_Human1.54738643
44FOXP2_21765815_ChIP-ChIP_NEURO2A_Mouse1.52799199
45IKZF1_21737484_ChIP-ChIP_HCT116_Human1.52303133
46SMAD4_21799915_ChIP-Seq_A2780_Human1.52253884
47TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse1.50734019
48PIAS1_25552417_ChIP-Seq_VCAP_Human1.47950478
49PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.44435574
50ZNF274_21170338_ChIP-Seq_K562_Hela1.44174952
51MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse1.43441400
52ZNF217_24962896_ChIP-Seq_MCF-7_Human1.41068331
53VDR_22108803_ChIP-Seq_LS180_Human1.37374162
54RARB_27405468_Chip-Seq_BRAIN_Mouse1.36193250
55TOP2B_26459242_ChIP-Seq_MCF-7_Human1.35964272
56SMAD3_21741376_ChIP-Seq_EPCs_Human1.34864848
57RING1B_27294783_Chip-Seq_ESCs_Mouse1.33519287
58MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human1.32822445
59SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.31038749
60* AHR_22903824_ChIP-Seq_MCF-7_Human1.29348619
61* ARNT_22903824_ChIP-Seq_MCF-7_Human1.29320826
62AR_25329375_ChIP-Seq_VCAP_Human1.28294925
63TP53_20018659_ChIP-ChIP_R1E_Mouse1.27275768
64SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.26914827
65FUS_26573619_Chip-Seq_HEK293_Human1.25549221
66ZFP322A_24550733_ChIP-Seq_MESCs_Mouse1.22630848
67STAT3_23295773_ChIP-Seq_U87_Human1.22258878
68KLF5_20875108_ChIP-Seq_MESCs_Mouse1.19381908
69NR3C1_21868756_ChIP-Seq_MCF10A_Human1.18725720
70ER_23166858_ChIP-Seq_MCF-7_Human1.18665636
71NOTCH1_17114293_ChIP-ChIP_T-ALL_Human1.17552918
72TP53_18474530_ChIP-ChIP_U2OS_Human1.16026866
73JUN_21703547_ChIP-Seq_K562_Human1.15580675
74* RING1B_27294783_Chip-Seq_NPCs_Mouse1.15544361
75* FLI1_27457419_Chip-Seq_LIVER_Mouse1.15541248
76EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.15002199
77SMAD3_21741376_ChIP-Seq_HESCs_Human1.14847036
78BCAT_22108803_ChIP-Seq_LS180_Human1.14483009
79OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.14450962
80IRF1_19129219_ChIP-ChIP_H3396_Human1.14086968
81TAL1_26923725_Chip-Seq_HPCs_Mouse1.13174986
82POU5F1_16153702_ChIP-ChIP_HESCs_Human1.12908043
83CEBPD_23245923_ChIP-Seq_MEFs_Mouse1.12648395
84POU3F2_20337985_ChIP-ChIP_501MEL_Human1.11880211
85SOX2_21211035_ChIP-Seq_LN229_Gbm1.11550413
86KLF4_25985364_ChIP-Seq_ATHEROSCLEROSIS_LESION_Mouse1.09643499
87MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human1.08534304
88IGF1R_20145208_ChIP-Seq_DFB_Human1.07914103
89CDX2_19796622_ChIP-Seq_MESCs_Mouse1.06868347
90RXR_22108803_ChIP-Seq_LS180_Human1.06540066
91TCF4_23295773_ChIP-Seq_U87_Human1.06045218
92SOX9_26525672_Chip-Seq_HEART_Mouse1.05637526
93* PCGF2_27294783_Chip-Seq_ESCs_Mouse1.03926188
94UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human1.03156563
95GATA1_26923725_Chip-Seq_HPCs_Mouse1.02981468
96SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.02862459
97MYC_18940864_ChIP-ChIP_HL60_Human1.02433075
98TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.01775930
99POU5F1_26923725_Chip-Seq_MESODERM_Mouse1.01775930
100PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse1.01409909
101GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse1.01135053
102TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human1.00680095
103* EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse1.00679999
104* AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human0.99861935
105NR3C1_23031785_ChIP-Seq_PC12_Mouse0.99721825
106MYCN_21190229_ChIP-Seq_SHEP-21N_Human0.99492988
107RCOR1_19997604_ChIP-ChIP_NEURONS_Mouse0.99325869
108* SOX9_24532713_ChIP-Seq_HFSC_Mouse0.99144806
109TRIM28_21343339_ChIP-Seq_HEK293_Human0.99062962
110* TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse0.98315467
111PRDM14_20953172_ChIP-Seq_ESCs_Human0.97893586
112SOX2_16153702_ChIP-ChIP_HESCs_Human0.96321064
113TFAP2C_20629094_ChIP-Seq_MCF-7_Human0.95813255
114FLI1_21867929_ChIP-Seq_TH2_Mouse0.94740875
115LMO2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.94309472
116CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons0.93929834
117* TEAD4_22529382_ChIP-Seq_TROPHECTODERM_Mouse0.93666899
118* P53_22387025_ChIP-Seq_ESCs_Mouse0.92403113
119WT1_25993318_ChIP-Seq_PODOCYTE_Human0.91865684
120SMAD4_21741376_ChIP-Seq_HESCs_Human0.91597420
121TRIM28_17542650_ChIP-ChIP_NTERA2_Human0.91182056
122TCF4_18268006_ChIP-ChIP_LS174T_Human0.90968336
123* NANOG_18555785_Chip-Seq_ESCs_Mouse0.90456921
124CEBPB_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.90419174
125* YAP1_20516196_ChIP-Seq_MESCs_Mouse0.89114204
126AR_19668381_ChIP-Seq_PC3_Human0.88963353
127* RUNX2_22187159_ChIP-Seq_PCA_Human0.88461899
128TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.88243616
129CEBPB_26923725_Chip-Seq_MESODERM_Mouse0.87591337
130KDM2B_26808549_Chip-Seq_REH_Human0.87056707
131TP53_16413492_ChIP-PET_HCT116_Human0.85861324
132HOXD13_18407260_ChIP-ChIP_DEVELOPING-LIMBS_Mouse0.85178742
133P53_22127205_ChIP-Seq_FIBROBLAST_Human0.84827822
134WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse0.84713864
135IRF4_20064451_ChIP-Seq_CD4+T_Mouse0.84223681
136CBP_20019798_ChIP-Seq_JUKART_Human0.84223681

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0004859_abnormal_synaptic_plasticity4.68208778
2MP0003880_abnormal_central_pattern4.07265849
3MP0003635_abnormal_synaptic_transmissio3.41924476
4MP0004270_analgesia3.16867866
5MP0002063_abnormal_learning/memory/cond2.85453467
6MP0009745_abnormal_behavioral_response2.75584032
7MP0002796_impaired_skin_barrier2.74752531
8MP0009046_muscle_twitch2.64888865
9MP0001968_abnormal_touch/_nociception2.61854562
10MP0002572_abnormal_emotion/affect_behav2.50080420
11MP0002064_seizures2.49429495
12MP0002822_catalepsy2.48839447
13MP0003941_abnormal_skin_development2.48664968
14MP0000778_abnormal_nervous_system2.41713382
15MP0002102_abnormal_ear_morphology2.28420571
16MP0006276_abnormal_autonomic_nervous2.25543045
17MP0009780_abnormal_chondrocyte_physiolo2.19289319
18MP0002736_abnormal_nociception_after2.16734049
19MP0001440_abnormal_grooming_behavior2.05538076
20MP0009379_abnormal_foot_pigmentation2.04985582
21MP0003121_genomic_imprinting2.00415812
22MP0002184_abnormal_innervation1.99655966
23MP0002734_abnormal_mechanical_nocicepti1.97801027
24MP0001501_abnormal_sleep_pattern1.97039022
25MP0001486_abnormal_startle_reflex1.95126978
26MP0002735_abnormal_chemical_nociception1.83216063
27MP0002557_abnormal_social/conspecific_i1.81631981
28MP0002272_abnormal_nervous_system1.79834964
29MP0002733_abnormal_thermal_nociception1.73588890
30MP0004885_abnormal_endolymph1.72659791
31MP0004043_abnormal_pH_regulation1.66917964
32MP0005423_abnormal_somatic_nervous1.64916848
33MP0002067_abnormal_sensory_capabilities1.64794074
34MP0001984_abnormal_olfaction1.61429910
35MP0004381_abnormal_hair_follicle1.59810513
36MP0005394_taste/olfaction_phenotype1.57401768
37MP0005499_abnormal_olfactory_system1.57401768
38MP0004858_abnormal_nervous_system1.55430476
39MP0001502_abnormal_circadian_rhythm1.55334914
40MP0002234_abnormal_pharynx_morphology1.55319413
41MP0005248_abnormal_Harderian_gland1.53402988
42MP0004019_abnormal_vitamin_homeostasis1.51847548
43MP0003221_abnormal_cardiomyocyte_apopto1.51344762
44MP0005501_abnormal_skin_physiology1.45225804
45MP0003879_abnormal_hair_cell1.45161487
46MP0008995_early_reproductive_senescence1.43543610
47MP0002638_abnormal_pupillary_reflex1.42751974
48MP0001765_abnormal_ion_homeostasis1.42559824
49MP0003329_amyloid_beta_deposits1.42035462
50MP0001970_abnormal_pain_threshold1.39446688
51MP0002751_abnormal_autonomic_nervous1.38863672
52MP0000049_abnormal_middle_ear1.35981257
53MP0004811_abnormal_neuron_physiology1.32442128
54MP0005253_abnormal_eye_physiology1.30879504
55MP0008789_abnormal_olfactory_epithelium1.26982870
56MP0004133_heterotaxia1.26976528
57MP0001905_abnormal_dopamine_level1.26409553
58MP0005187_abnormal_penis_morphology1.25311939
59MP0003011_delayed_dark_adaptation1.23942959
60MP0010234_abnormal_vibrissa_follicle1.23533679
61MP0002837_dystrophic_cardiac_calcinosis1.21818000
62MP0003938_abnormal_ear_development1.19798661
63MP0002254_reproductive_system_inflammat1.18663910
64MP0000569_abnormal_digit_pigmentation1.18035210
65MP0010771_integument_phenotype1.17556204
66MP0002653_abnormal_ependyma_morphology1.16078071
67MP0002882_abnormal_neuron_morphology1.14884864
68MP0008961_abnormal_basal_metabolism1.14863120
69MP0008569_lethality_at_weaning1.14347578
70MP0003122_maternal_imprinting1.14198868
71MP0006072_abnormal_retinal_apoptosis1.13330769
72MP0005551_abnormal_eye_electrophysiolog1.13269918
73MP0005645_abnormal_hypothalamus_physiol1.13063416
74MP0006292_abnormal_olfactory_placode1.13022132
75MP0000383_abnormal_hair_follicle1.12868078
76MP0000538_abnormal_urinary_bladder1.12287880
77MP0003136_yellow_coat_color1.10556220
78MP0005409_darkened_coat_color1.10105023
79MP0000467_abnormal_esophagus_morphology1.08982598
80MP0002066_abnormal_motor_capabilities/c1.08947311
81MP0003861_abnormal_nervous_system1.07839339
82MP0005386_behavior/neurological_phenoty1.07008397
83MP0004924_abnormal_behavior1.07008397
84MP0001529_abnormal_vocalization1.06810532
85MP0000537_abnormal_urethra_morphology1.06438431
86MP0002233_abnormal_nose_morphology1.06278752
87MP0001216_abnormal_epidermal_layer1.05442049
88MP0000566_synostosis1.03622203
89MP0002909_abnormal_adrenal_gland1.03152092
90MP0000751_myopathy1.00847075
91MP0002098_abnormal_vibrissa_morphology1.00747455
92MP0003119_abnormal_digestive_system1.00631328
93MP0004142_abnormal_muscle_tone1.00276757
94MP0003890_abnormal_embryonic-extraembry0.98613829
95MP0000955_abnormal_spinal_cord0.98542222
96MP0000631_abnormal_neuroendocrine_gland0.97534269
97MP0000579_abnormal_nail_morphology0.96465333
98MP0003937_abnormal_limbs/digits/tail_de0.95440040
99MP0005646_abnormal_pituitary_gland0.94258041
100MP0003315_abnormal_perineum_morphology0.94154931
101MP0000647_abnormal_sebaceous_gland0.92519857
102MP0002152_abnormal_brain_morphology0.89985958
103MP0000427_abnormal_hair_cycle0.89870327
104MP0001299_abnormal_eye_distance/0.89371033
105MP0000026_abnormal_inner_ear0.88157173
106MP0010386_abnormal_urinary_bladder0.87064087
107MP0001188_hyperpigmentation0.84451703
108MP0002069_abnormal_eating/drinking_beha0.83242471
109MP0003567_abnormal_fetal_cardiomyocyte0.82985184
110MP0005360_urolithiasis0.82827140
111MP0003137_abnormal_impulse_conducting0.81933896
112MP0002249_abnormal_larynx_morphology0.81337839
113MP0004742_abnormal_vestibular_system0.81153874
114MP0001177_atelectasis0.81146337
115MP0005195_abnormal_posterior_eye0.80938661
116MP0003755_abnormal_palate_morphology0.80772091
117MP0008874_decreased_physiological_sensi0.80390135
118MP0003787_abnormal_imprinting0.80295107
119MP0002090_abnormal_vision0.77239164
120MP0003385_abnormal_body_wall0.76730826
121MP0002229_neurodegeneration0.75855773
122MP0001963_abnormal_hearing_physiology0.75633509
123MP0002876_abnormal_thyroid_physiology0.75577141
124MP0003638_abnormal_response/metabolism_0.75159007
125MP0010678_abnormal_skin_adnexa0.75005959
126MP0002752_abnormal_somatic_nervous0.74836254
127MP0005391_vision/eye_phenotype0.73530411
128MP0001346_abnormal_lacrimal_gland0.73405460
129MP0004147_increased_porphyrin_level0.73224404
130MP0008877_abnormal_DNA_methylation0.72983824
131MP0006035_abnormal_mitochondrial_morpho0.72120792
132MP0001986_abnormal_taste_sensitivity0.72092369
133MP0004484_altered_response_of0.71583474
134MP0000516_abnormal_urinary_system0.71324042
135MP0005367_renal/urinary_system_phenotyp0.71324042
136MP0001340_abnormal_eyelid_morphology0.69463432
137MP0001664_abnormal_digestion0.68198289
138MP0004215_abnormal_myocardial_fiber0.68195147
139MP0003633_abnormal_nervous_system0.67184183

Predicted human phenotypes

RankGene SetZ-score
1Focal motor seizures (HP:0011153)5.57689701
2Increased circulating renin level (HP:0000848)4.74209280
3Hyperventilation (HP:0002883)4.29629408
4Metabolic alkalosis (HP:0200114)4.10973460
5Focal seizures (HP:0007359)4.07465076
6Hyperactive renin-angiotensin system (HP:0000841)4.06332416
7Epileptic encephalopathy (HP:0200134)4.02268831
8Gait imbalance (HP:0002141)3.85546294
9Polyphagia (HP:0002591)3.82212748
10Myokymia (HP:0002411)3.78326888
11Hypokalemic alkalosis (HP:0001949)3.64853956
12Hypomagnesemia (HP:0002917)3.56617374
13Visual hallucinations (HP:0002367)3.50894611
14Congenital primary aphakia (HP:0007707)3.49466224
15Absence seizures (HP:0002121)3.35046813
16Cortical dysplasia (HP:0002539)3.32104642
17Broad-based gait (HP:0002136)3.32029964
18Medial flaring of the eyebrow (HP:0010747)3.30138985
19Nephrogenic diabetes insipidus (HP:0009806)3.23344252
20Polyuria (HP:0000103)3.22635899
21Gout (HP:0001997)3.11271779
22Abnormal eating behavior (HP:0100738)3.10404803
23Hypotrichosis (HP:0001006)3.08029304
24Atonic seizures (HP:0010819)3.05181371
25Abnormality of chloride homeostasis (HP:0011422)3.03386659
26Shoulder girdle muscle weakness (HP:0003547)3.01514364
27Progressive cerebellar ataxia (HP:0002073)2.99903598
28Parakeratosis (HP:0001036)2.97260801
29Dialeptic seizures (HP:0011146)2.91070997
30Abnormal urine output (HP:0012590)2.90565616
31Abnormality of the hip-girdle musculature (HP:0001445)2.87440472
32Abnormality of the musculature of the pelvis (HP:0001469)2.87440472
33Abnormal drinking behavior (HP:0030082)2.84182725
34Polydipsia (HP:0001959)2.84182725
35Cerebral inclusion bodies (HP:0100314)2.78938698
36Febrile seizures (HP:0002373)2.77412941
37Abnormality of renin-angiotensin system (HP:0000847)2.77405853
38Abnormality of magnesium homeostasis (HP:0004921)2.75930088
39Abnormality of the labia minora (HP:0012880)2.75383812
40Abnormality of renal excretion (HP:0011036)2.74311926
41Urinary urgency (HP:0000012)2.73546623
42Genital tract atresia (HP:0001827)2.73287306
43Vaginal atresia (HP:0000148)2.73132264
44Generalized tonic-clonic seizures (HP:0002069)2.71057727
45Abnormality of the axillary hair (HP:0100134)2.68782355
46Abnormality of secondary sexual hair (HP:0009888)2.68782355
47Specific learning disability (HP:0001328)2.66187290
48Excessive salivation (HP:0003781)2.65945771
49Drooling (HP:0002307)2.65945771
50Septo-optic dysplasia (HP:0100842)2.62748524
51Split foot (HP:0001839)2.60291292
52Retinal dysplasia (HP:0007973)2.59971151
53Obstructive sleep apnea (HP:0002870)2.59669382
54Degeneration of the lateral corticospinal tracts (HP:0002314)2.59324672
55Atrophy/Degeneration involving the corticospinal tracts (HP:0007372)2.59324672
56Lissencephaly (HP:0001339)2.56949393
57Elevated circulating parathyroid hormone (PTH) level (HP:0003165)2.55099908
58Hyperaldosteronism (HP:0000859)2.54534084
59Abnormality of the corticospinal tract (HP:0002492)2.52389554
60Amblyopia (HP:0000646)2.50236071
61Optic nerve hypoplasia (HP:0000609)2.49955393
62Neurofibrillary tangles (HP:0002185)2.48890710
63Spastic gait (HP:0002064)2.45246175
64Partial agenesis of the corpus callosum (HP:0001338)2.41754122
65Poor coordination (HP:0002370)2.38775976
66Unilateral renal agenesis (HP:0000122)2.37683997
67Pelvic girdle muscle weakness (HP:0003749)2.33871048
68Poor suck (HP:0002033)2.30984114
69Exotropia (HP:0000577)2.29986442
70Hepatoblastoma (HP:0002884)2.25208067
71Epileptiform EEG discharges (HP:0011182)2.23508379
72Supranuclear gaze palsy (HP:0000605)2.22916653
73Abnormality of binocular vision (HP:0011514)2.21876478
74Diplopia (HP:0000651)2.21876478
75Colon cancer (HP:0003003)2.20637099
76Fetal akinesia sequence (HP:0001989)2.20204506
77Impaired vibration sensation in the lower limbs (HP:0002166)2.20120614
78True hermaphroditism (HP:0010459)2.19403184
79Failure to thrive in infancy (HP:0001531)2.16296783
80Broad foot (HP:0001769)2.16223786
81Lower limb muscle weakness (HP:0007340)2.16176394
82Decreased testicular size (HP:0008734)2.15747900
83Fragile nails (HP:0001808)2.15718214
84Pachygyria (HP:0001302)2.15077199
85Aplasia/Hypoplasia of the brainstem (HP:0007362)2.14991080
86Hypoplasia of the brainstem (HP:0002365)2.14991080
87Labial hypoplasia (HP:0000066)2.12488143
88Postaxial hand polydactyly (HP:0001162)2.12186415
89Papillary thyroid carcinoma (HP:0002895)2.11720482
90Amyotrophic lateral sclerosis (HP:0007354)2.07867803
91Absent eyebrow (HP:0002223)2.06370806
92Akinesia (HP:0002304)2.06360724
93Inability to walk (HP:0002540)2.06252652
94Limb dystonia (HP:0002451)2.05922044
95Spastic tetraplegia (HP:0002510)2.03733914
96Abnormality of the lower motor neuron (HP:0002366)2.03672440
97EEG with generalized epileptiform discharges (HP:0011198)2.03480317
98Abnormality of calcium-phosphate metabolism (HP:0100530)2.03452097
99Oligodontia (HP:0000677)2.03105364
100Plantar hyperkeratosis (HP:0007556)2.02956537
101Atrophy/Degeneration involving motor neurons (HP:0007373)2.02250555
102Hyperthyroidism (HP:0000836)2.01268870
103Renal salt wasting (HP:0000127)2.00537712
104Aplasia/Hypoplasia of the optic nerve (HP:0008058)1.99357996
105Alkalosis (HP:0001948)1.99044877
106Anxiety (HP:0000739)1.97171711
107Esotropia (HP:0000565)1.96680714
108Thyroid-stimulating hormone excess (HP:0002925)1.96592351
109Morphological abnormality of the pyramidal tract (HP:0002062)1.96275145
110Morphological abnormality of the middle ear (HP:0008609)1.94503185
111Dysdiadochokinesis (HP:0002075)1.94432016
112Pancreatic cysts (HP:0001737)1.94086783
113Hypoplasia of the corpus callosum (HP:0002079)1.93868946
114Hip dysplasia (HP:0001385)1.93729172
115Agitation (HP:0000713)1.93711691
116Abnormality of salivation (HP:0100755)1.93468003
117Paraplegia (HP:0010550)1.93218883
118Conjunctival hamartoma (HP:0100780)1.92615466
119Concave nail (HP:0001598)1.92430770
120Micropenis (HP:0000054)1.92244809
121Absent speech (HP:0001344)1.91957216
122Hypercalciuria (HP:0002150)1.91014474
123Tubular atrophy (HP:0000092)1.90933142
124Decreased number of large peripheral myelinated nerve fibers (HP:0003387)1.90762243
125Abnormality of midbrain morphology (HP:0002418)1.90673432
126Molar tooth sign on MRI (HP:0002419)1.90673432
127Narrow forehead (HP:0000341)1.89246102
128Hypsarrhythmia (HP:0002521)1.88375628
129Tetany (HP:0001281)1.88332834
130Poor eye contact (HP:0000817)1.88296634
131Pancreatic fibrosis (HP:0100732)1.87297258
132Aplasia/Hypoplasia of the lens (HP:0008063)1.87055901
133Advanced eruption of teeth (HP:0006288)1.85657106
134Pendular nystagmus (HP:0012043)1.84798790
135Nephronophthisis (HP:0000090)1.84513777
136Sleep apnea (HP:0010535)1.83766063
137Short tibia (HP:0005736)1.83323222
138Hypoplastic female external genitalia (HP:0012815)1.83151980
139Pheochromocytoma (HP:0002666)1.82326573
140Ankle clonus (HP:0011448)1.81721402
141Impaired social interactions (HP:0000735)1.81514051
142Abnormal social behavior (HP:0012433)1.81514051
143Aqueductal stenosis (HP:0002410)1.80305745
144Intestinal atresia (HP:0011100)1.79410829
145Aplasia/Hypoplasia of the tibia (HP:0005772)1.78636936
146Lip pit (HP:0100267)1.77530443
147Palmoplantar hyperkeratosis (HP:0000972)1.77032323
148Occipital encephalocele (HP:0002085)1.76239747
149Astrocytoma (HP:0009592)1.75170321
150Abnormality of the astrocytes (HP:0100707)1.75170321
151Muscular hypotonia of the trunk (HP:0008936)1.74764994
152Mutism (HP:0002300)1.74658050
153Ketoacidosis (HP:0001993)1.74035761
154Gastroesophageal reflux (HP:0002020)1.73827527
155Spastic paraplegia (HP:0001258)1.73077418
156Hypocalcemia (HP:0002901)1.72281356
157Increased purine levels (HP:0004368)1.72249324
158Hyperuricemia (HP:0002149)1.72249324
159Insidious onset (HP:0003587)1.71782090
160Termporal pattern (HP:0011008)1.71782090
161Dehydration (HP:0001944)1.71442085
162Generalized myoclonic seizures (HP:0002123)1.69539905
163Urinary bladder sphincter dysfunction (HP:0002839)1.69522404
164Progressive inability to walk (HP:0002505)1.69306453
165Absent septum pellucidum (HP:0001331)1.68626623
166Hemiparesis (HP:0001269)1.68345816
167Severe Myopia (HP:0011003)1.67698734
168Decreased circulating renin level (HP:0003351)1.66369586
169Natal tooth (HP:0000695)1.64274074
170Truncal ataxia (HP:0002078)1.63871179
171Action tremor (HP:0002345)1.63449730
172Gaze-evoked nystagmus (HP:0000640)1.63445881

Predicted kinase interactions (KEA)

RankGene SetZ-score
1CASK4.05540399
2MARK13.92390422
3NTRK33.47320686
4MAP3K123.28523097
5EPHA43.26237517
6WNK33.10489107
7MST1R2.98778006
8OXSR12.77336577
9MAP3K92.63156979
10TRIM282.57515903
11NTRK22.49857441
12EPHB22.48061491
13MINK12.39521968
14MAP3K42.35202287
15WNK42.24547824
16MAP4K22.02744868
17RIPK41.98588852
18MAP2K41.88814435
19CSNK1A1L1.85112115
20SRPK11.78590072
21EPHA31.77487135
22DYRK31.75260630
23MAP2K71.70471556
24KSR11.69448743
25ERBB31.60316170
26PINK11.59173356
27RPS6KA41.58795073
28GRK51.51282566
29UHMK11.49522369
30SIK31.46693348
31CSNK1G11.46257868
32CDK191.45528384
33PLK21.43403510
34MAPK131.37321287
35MAP3K21.35429705
36BCKDK1.34859310
37FER1.32490715
38DYRK21.21166590
39BCR1.19223362
40FRK1.18134680
41CDK51.16156191
42PAK61.13550387
43DAPK21.07218791
44STK391.02648381
45DAPK11.01912472
46DYRK1B1.01750207
47PRPF4B1.00995277
48GRK71.00826184
49BMPR1B0.97447192
50PRKCG0.96850143
51CAMK2A0.96355618
52SGK4940.93747816
53SGK2230.93747816
54CAMKK20.93717986
55PNCK0.89940193
56FGR0.88060824
57SIK20.87288710
58PDK30.86902627
59PDK40.86902627
60PAK30.83719000
61BMPR20.83695150
62DYRK1A0.83497525
63FGFR20.83408980
64PHKG20.80123598
65PHKG10.80123598
66TNIK0.79357229
67CDC42BPA0.78471497
68NTRK10.72828476
69PRKD30.72155695
70MARK20.70700596
71SGK10.69710779
72STK110.69480224
73CAMK40.69446787
74LATS20.69410182
75CSNK1G20.69182111
76PRKCE0.69140886
77CDK180.68028796
78KSR20.67819858
79TYRO30.67298538
80INSRR0.65710235
81MKNK10.65369115
82BRD40.64343924
83MST40.64090053
84BRSK10.62572533
85CDK140.61509889
86CDK150.59896132
87ADRBK10.58712748
88CDK30.58441077
89SGK20.57531904
90CAMK2B0.56871620
91STK38L0.55865851
92VRK10.55139841
93CCNB10.54483495
94MAP3K50.53789850
95MAPKAPK30.53413853
96CDK11A0.51396749
97TAOK10.51142096
98PRKCZ0.50291838
99TESK10.49763447
100PKN10.49139666
101FES0.47529183
102LIMK10.46687792
103PTK2B0.45219799
104NME10.44506460
105MKNK20.43336021
106TSSK60.42228542
107ROCK20.41224166
108MAP3K60.40578771
109CSNK1A10.40539840
110CAMKK10.39937042
111CAMK2G0.39902210
112CSNK1D0.39603641
113CAMK10.39571354
114GRK60.36839544
115MET0.36747663
116RPS6KA50.36607579
117GRK10.36089971
118PRKACB0.36082353
119RPS6KA20.35232368
120MAPK120.35157474
121ADRBK20.34797813
122AKT30.34749485
123PRKACA0.33975684
124CSNK1G30.33839328
125PLK30.33668576
126FYN0.33493927
127LATS10.32330196
128PRKCI0.30102375
129PDK20.30101817
130PRKAA10.29839797
131PRKCA0.29823312
132MAPK90.29675053
133STK240.29506114
134AURKA0.29412942
135ERBB40.29386394
136RET0.29375961
137STK380.29322977
138MAP3K70.29189342
139CSNK1E0.29094148
140PIM20.27717051
141TIE10.27473534
142PKN20.27028671
143MAPKAPK50.25453961
144PRKG10.25346867

Predicted pathways (KEGG)

RankGene SetZ-score
1Nicotine addiction_Homo sapiens_hsa050333.66901804
2Taurine and hypotaurine metabolism_Homo sapiens_hsa004303.06584292
3Cyanoamino acid metabolism_Homo sapiens_hsa004602.94120081
4Synaptic vesicle cycle_Homo sapiens_hsa047212.92708444
5Collecting duct acid secretion_Homo sapiens_hsa049662.75930891
6Retrograde endocannabinoid signaling_Homo sapiens_hsa047232.36158515
7Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049612.28198126
8GABAergic synapse_Homo sapiens_hsa047272.19990177
9Protein export_Homo sapiens_hsa030602.19278913
10Synthesis and degradation of ketone bodies_Homo sapiens_hsa000722.15076682
11Glutamatergic synapse_Homo sapiens_hsa047242.14883307
12Circadian entrainment_Homo sapiens_hsa047132.14371822
13Serotonergic synapse_Homo sapiens_hsa047261.99451773
14Long-term potentiation_Homo sapiens_hsa047201.99398005
15Amphetamine addiction_Homo sapiens_hsa050311.94607863
16Salivary secretion_Homo sapiens_hsa049701.91332721
17Morphine addiction_Homo sapiens_hsa050321.89639300
18Renin secretion_Homo sapiens_hsa049241.85588026
19Dopaminergic synapse_Homo sapiens_hsa047281.85071183
20Butanoate metabolism_Homo sapiens_hsa006501.85045370
21Taste transduction_Homo sapiens_hsa047421.82827052
22Steroid biosynthesis_Homo sapiens_hsa001001.76898224
23Gastric acid secretion_Homo sapiens_hsa049711.76436854
24Olfactory transduction_Homo sapiens_hsa047401.74108707
25Axon guidance_Homo sapiens_hsa043601.71908027
26Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049641.65316118
27Long-term depression_Homo sapiens_hsa047301.63599227
28Oxidative phosphorylation_Homo sapiens_hsa001901.56067599
29Terpenoid backbone biosynthesis_Homo sapiens_hsa009001.49267862
30Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005631.43587552
31Cocaine addiction_Homo sapiens_hsa050301.41584334
32Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001301.41361841
33Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049601.36657640
34Vasopressin-regulated water reabsorption_Homo sapiens_hsa049621.31294697
35Calcium signaling pathway_Homo sapiens_hsa040201.30436009
36Oxytocin signaling pathway_Homo sapiens_hsa049211.27089919
37Cholinergic synapse_Homo sapiens_hsa047251.24350931
38Insulin secretion_Homo sapiens_hsa049111.22735947
39Gap junction_Homo sapiens_hsa045401.18566701
40Aldosterone synthesis and secretion_Homo sapiens_hsa049251.16071651
41Regulation of autophagy_Homo sapiens_hsa041401.15811193
42Neuroactive ligand-receptor interaction_Homo sapiens_hsa040801.13923095
43Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042611.13692497
44Cardiac muscle contraction_Homo sapiens_hsa042601.12722040
45Alzheimers disease_Homo sapiens_hsa050101.12238283
46GnRH signaling pathway_Homo sapiens_hsa049121.11272586
47Vibrio cholerae infection_Homo sapiens_hsa051101.11151511
48Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051201.10732693
49Phototransduction_Homo sapiens_hsa047441.09906329
50Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047501.07843351
51Circadian rhythm_Homo sapiens_hsa047101.02453927
52Melanogenesis_Homo sapiens_hsa049161.01001986
53Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.98761104
54Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.94841230
55Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.94536287
56Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.89544500
57Estrogen signaling pathway_Homo sapiens_hsa049150.87157301
58ErbB signaling pathway_Homo sapiens_hsa040120.85945679
59cAMP signaling pathway_Homo sapiens_hsa040240.85780003
60Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.85403487
61Alcoholism_Homo sapiens_hsa050340.84391018
62Parkinsons disease_Homo sapiens_hsa050120.84389694
63Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.82763088
64Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005340.76330824
65Glioma_Homo sapiens_hsa052140.74767825
66Phosphatidylinositol signaling system_Homo sapiens_hsa040700.74663750
67Choline metabolism in cancer_Homo sapiens_hsa052310.73461044
68Basal transcription factors_Homo sapiens_hsa030220.69557216
69Peroxisome_Homo sapiens_hsa041460.69300972
70cGMP-PKG signaling pathway_Homo sapiens_hsa040220.64660006
71Phenylalanine metabolism_Homo sapiens_hsa003600.64457872
72VEGF signaling pathway_Homo sapiens_hsa043700.63109325
73Pancreatic secretion_Homo sapiens_hsa049720.63025092
74Mineral absorption_Homo sapiens_hsa049780.62991208
752-Oxocarboxylic acid metabolism_Homo sapiens_hsa012100.59638063
76mRNA surveillance pathway_Homo sapiens_hsa030150.59383070
77AMPK signaling pathway_Homo sapiens_hsa041520.58643849
78Vascular smooth muscle contraction_Homo sapiens_hsa042700.55683228
79Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.54796511
80Hedgehog signaling pathway_Homo sapiens_hsa043400.53826020
81Fanconi anemia pathway_Homo sapiens_hsa034600.52781138
82Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009700.51948111
83Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.51390206
84RNA degradation_Homo sapiens_hsa030180.51067399
85Thyroid hormone synthesis_Homo sapiens_hsa049180.50358867
86Ras signaling pathway_Homo sapiens_hsa040140.49860194
87Huntingtons disease_Homo sapiens_hsa050160.49524584
88Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.49170747
89Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.48994158
90Rap1 signaling pathway_Homo sapiens_hsa040150.48835528
91Ascorbate and aldarate metabolism_Homo sapiens_hsa000530.48225681
92Carbohydrate digestion and absorption_Homo sapiens_hsa049730.47308349
93Type II diabetes mellitus_Homo sapiens_hsa049300.47288766
94Sphingolipid metabolism_Homo sapiens_hsa006000.47242101
95Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010400.46949201
96Fatty acid elongation_Homo sapiens_hsa000620.46701174
97Wnt signaling pathway_Homo sapiens_hsa043100.46344636
98Spliceosome_Homo sapiens_hsa030400.45747389
99MAPK signaling pathway_Homo sapiens_hsa040100.45716529
100Phagosome_Homo sapiens_hsa041450.44381839
101Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.43402046
102Inositol phosphate metabolism_Homo sapiens_hsa005620.43088643
103Arginine and proline metabolism_Homo sapiens_hsa003300.41951629
104Ether lipid metabolism_Homo sapiens_hsa005650.41648892
105Sphingolipid signaling pathway_Homo sapiens_hsa040710.40531367
106Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006300.40131982
107Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004000.39742504
108Bile secretion_Homo sapiens_hsa049760.39695969
109Pyruvate metabolism_Homo sapiens_hsa006200.39265731
110Sulfur relay system_Homo sapiens_hsa041220.39142317
111Oocyte meiosis_Homo sapiens_hsa041140.39123071
112Propanoate metabolism_Homo sapiens_hsa006400.36596738
113Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049320.36555646
114Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.35828615
115Valine, leucine and isoleucine degradation_Homo sapiens_hsa002800.35665231
116Fatty acid biosynthesis_Homo sapiens_hsa000610.35087625
117Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.34812211
118Dorso-ventral axis formation_Homo sapiens_hsa043200.34240108
119Endometrial cancer_Homo sapiens_hsa052130.33789700
120Rheumatoid arthritis_Homo sapiens_hsa053230.33649969
121Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.33384153
122Basal cell carcinoma_Homo sapiens_hsa052170.33292487
123Citrate cycle (TCA cycle)_Homo sapiens_hsa000200.32767767
124beta-Alanine metabolism_Homo sapiens_hsa004100.32502792
125Hippo signaling pathway_Homo sapiens_hsa043900.32445218
126Primary bile acid biosynthesis_Homo sapiens_hsa001200.31724378
127RNA transport_Homo sapiens_hsa030130.31697406
128Glucagon signaling pathway_Homo sapiens_hsa049220.31590156
129Non-homologous end-joining_Homo sapiens_hsa034500.31303324
130Phospholipase D signaling pathway_Homo sapiens_hsa040720.30651196
131Metabolic pathways_Homo sapiens_hsa011000.30640791
132Fatty acid metabolism_Homo sapiens_hsa012120.30358118
133Biosynthesis of amino acids_Homo sapiens_hsa012300.30244735
134Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.30008036
135Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054120.27898018
136Cysteine and methionine metabolism_Homo sapiens_hsa002700.27047056
137Steroid hormone biosynthesis_Homo sapiens_hsa001400.26921020

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