SKA2

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1kinetochore organization (GO:0051383)5.72052013
2kinetochore assembly (GO:0051382)5.30034488
3CENP-A containing nucleosome assembly (GO:0034080)4.95031538
4protein localization to kinetochore (GO:0034501)4.85850985
5chromatin remodeling at centromere (GO:0031055)4.76642408
6mitotic metaphase plate congression (GO:0007080)4.66990002
7regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:00450914.49410713
8DNA strand elongation involved in DNA replication (GO:0006271)4.39174071
9DNA replication-independent nucleosome organization (GO:0034724)4.36055325
10DNA replication-independent nucleosome assembly (GO:0006336)4.36055325
11metaphase plate congression (GO:0051310)4.33045185
12DNA unwinding involved in DNA replication (GO:0006268)4.32978078
13telomere maintenance via semi-conservative replication (GO:0032201)4.32281711
14protein localization to chromosome, centromeric region (GO:0071459)4.29959194
15mitotic sister chromatid segregation (GO:0000070)4.25067200
16sister chromatid segregation (GO:0000819)4.22880548
17DNA strand elongation (GO:0022616)4.21123201
18mitotic chromosome condensation (GO:0007076)4.10942674
19mitotic recombination (GO:0006312)4.08223830
20histone exchange (GO:0043486)4.07514422
21telomere maintenance via recombination (GO:0000722)3.99436670
22establishment of chromosome localization (GO:0051303)3.98899212
23attachment of spindle microtubules to kinetochore (GO:0008608)3.96636725
24DNA replication initiation (GO:0006270)3.90029292
25cornea development in camera-type eye (GO:0061303)3.83938901
26DNA replication checkpoint (GO:0000076)3.80136724
27spindle checkpoint (GO:0031577)3.79722236
28nucleotide-excision repair, DNA gap filling (GO:0006297)3.68651419
29DNA topological change (GO:0006265)3.67894232
30regulation of attachment of spindle microtubules to kinetochore (GO:0051988)3.67129940
31DNA ligation (GO:0006266)3.57419235
32regulation of spindle organization (GO:0090224)3.56845948
33microtubule depolymerization (GO:0007019)3.55387328
34spindle assembly checkpoint (GO:0071173)3.55058481
35telomere maintenance via telomere lengthening (GO:0010833)3.54946892
36negative regulation of mitotic sister chromatid separation (GO:2000816)3.51186513
37negative regulation of mitotic sister chromatid segregation (GO:0033048)3.51186513
38negative regulation of mitotic metaphase/anaphase transition (GO:0045841)3.51186513
39negative regulation of sister chromatid segregation (GO:0033046)3.51186513
40negative regulation of chromosome segregation (GO:0051985)3.47712511
41protein K6-linked ubiquitination (GO:0085020)3.45681608
42replication fork processing (GO:0031297)3.43927944
43mitotic spindle assembly checkpoint (GO:0007094)3.43423274
44DNA replication-dependent nucleosome assembly (GO:0006335)3.43111373
45DNA replication-dependent nucleosome organization (GO:0034723)3.43111373
46mitotic spindle checkpoint (GO:0071174)3.42036053
47proteasome assembly (GO:0043248)3.41109995
48negative regulation of metaphase/anaphase transition of cell cycle (GO:1902100)3.40707977
49regulation of mitotic metaphase/anaphase transition (GO:0030071)3.36702760
50regulation of chromosome segregation (GO:0051983)3.35122568
51ATP-dependent chromatin remodeling (GO:0043044)3.34275287
52* chromosome segregation (GO:0007059)3.32324480
53protein localization to chromosome (GO:0034502)3.31993616
54nuclear pore organization (GO:0006999)3.31779059
55regulation of metaphase/anaphase transition of cell cycle (GO:1902099)3.28934886
56mitotic nuclear envelope disassembly (GO:0007077)3.28244114
57meiotic chromosome segregation (GO:0045132)3.27168535
58regulation of development, heterochronic (GO:0040034)3.24257061
59establishment of integrated proviral latency (GO:0075713)3.23874477
60regulation of sister chromatid segregation (GO:0033045)3.23119073
61regulation of mitotic sister chromatid separation (GO:0010965)3.23119073
62regulation of mitotic sister chromatid segregation (GO:0033047)3.23119073
63regulation of transcription involved in G1/S transition of mitotic cell cycle (GO:0000083)3.20072802
64limb bud formation (GO:0060174)3.18256220
65resolution of meiotic recombination intermediates (GO:0000712)3.17111420
66regulation of timing of cell differentiation (GO:0048505)3.17031658
67spliceosomal complex assembly (GO:0000245)3.14917694
68negative regulation of mRNA splicing, via spliceosome (GO:0048025)3.10994352
69chromatin assembly or disassembly (GO:0006333)3.10428742
70histone H2A acetylation (GO:0043968)3.10199040
71ribosomal small subunit assembly (GO:0000028)3.09767498
72nuclear pore complex assembly (GO:0051292)3.08438924
73establishment of protein localization to mitochondrial membrane (GO:0090151)3.07666088
74viral mRNA export from host cell nucleus (GO:0046784)3.07516753
75spliceosomal snRNP assembly (GO:0000387)3.05181827
76negative regulation of RNA splicing (GO:0033119)3.04362912
77regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051439)3.03220854
78regulation of centrosome cycle (GO:0046605)3.00750013
79membrane disassembly (GO:0030397)3.00512507
80nuclear envelope disassembly (GO:0051081)3.00512507
81regulation of mitotic spindle organization (GO:0060236)2.99839778
82deoxyribonucleoside monophosphate metabolic process (GO:0009162)2.97096834
83regulation of DNA endoreduplication (GO:0032875)2.93760922
84mitotic sister chromatid cohesion (GO:0007064)2.93665499
85cullin deneddylation (GO:0010388)2.93194578
86* mitotic cell cycle (GO:0000278)2.92256257
87negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436)2.92186517
88regulation of double-strand break repair via homologous recombination (GO:0010569)2.91826085
89deoxyribonucleotide biosynthetic process (GO:0009263)2.90607932
90DNA double-strand break processing (GO:0000729)2.90365602
91mRNA splicing, via spliceosome (GO:0000398)2.89760681
92RNA splicing, via transesterification reactions with bulged adenosine as nucleophile (GO:0000377)2.89760681
93negative regulation of mitosis (GO:0045839)2.89272478
94microtubule polymerization or depolymerization (GO:0031109)2.89169686
95RNA splicing, via transesterification reactions (GO:0000375)2.88947845
96termination of RNA polymerase II transcription (GO:0006369)2.88717736
97chromosome condensation (GO:0030261)2.88657235
98negative regulation of DNA-dependent DNA replication (GO:2000104)2.88539810
99positive regulation of chromosome segregation (GO:0051984)2.87427266
100DNA damage response, detection of DNA damage (GO:0042769)2.86428654
101positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051437)2.84130589
102negative regulation of mRNA processing (GO:0050686)2.83465211
103viral transcription (GO:0019083)2.82909957
104anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process (GO:02.82259480
105ribosomal small subunit biogenesis (GO:0042274)2.81820680
106maturation of SSU-rRNA (GO:0030490)2.81224444
107transcription-coupled nucleotide-excision repair (GO:0006283)2.80612530
108regulation of mitotic spindle checkpoint (GO:1903504)2.80602469
109regulation of mitotic cell cycle spindle assembly checkpoint (GO:0090266)2.80602469
110translational termination (GO:0006415)2.79851286
111regulation of nuclear cell cycle DNA replication (GO:0033262)2.79542525
112regulation of sister chromatid cohesion (GO:0007063)2.78914802
113regulation of centriole replication (GO:0046599)2.76428921
114telomere maintenance (GO:0000723)2.76228960
115nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291)2.75576794
116telomere organization (GO:0032200)2.75451851
117mitochondrial ATP synthesis coupled proton transport (GO:0042776)2.74986759
118DNA strand renaturation (GO:0000733)2.74640114
119chaperone-mediated protein transport (GO:0072321)2.74347216
120exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay 2.74056480
121DNA catabolic process, exonucleolytic (GO:0000738)2.74040894
122mismatch repair (GO:0006298)2.72913455
123translesion synthesis (GO:0019985)2.69656292
124hindbrain development (GO:0030902)2.68543114
125protein deneddylation (GO:0000338)2.67154358
126postreplication repair (GO:0006301)2.66899874
127maintenance of fidelity involved in DNA-dependent DNA replication (GO:0045005)2.66866242
128pyrimidine nucleobase catabolic process (GO:0006208)2.65395406
129synapsis (GO:0007129)2.61291793
130negative regulation of ligase activity (GO:0051352)2.59453013
131negative regulation of ubiquitin-protein transferase activity (GO:0051444)2.59453013
132centriole replication (GO:0007099)2.56705565
133protein neddylation (GO:0045116)2.56384563
134recombinational repair (GO:0000725)2.56223560
135positive regulation of ubiquitin-protein transferase activity (GO:0051443)2.53378469
136double-strand break repair via nonhomologous end joining (GO:0006303)2.53030954
137non-recombinational repair (GO:0000726)2.53030954
138protein K11-linked ubiquitination (GO:0070979)2.51839579
139mitotic spindle organization (GO:0007052)2.50478645
140double-strand break repair via homologous recombination (GO:0000724)2.50180132
141histone mRNA metabolic process (GO:0008334)2.49541149

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1E2F7_22180533_ChIP-Seq_HELA_Human9.53925709
2* FOXM1_23109430_ChIP-Seq_U2OS_Human6.36991116
3E2F4_17652178_ChIP-ChIP_JURKAT_Human4.88934397
4* FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human4.32137184
5MYC_18555785_ChIP-Seq_MESCs_Mouse3.84651565
6KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human3.53141638
7HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse3.44022888
8HCFC1_20581084_ChIP-Seq_MESCs_Mouse2.98144819
9EST1_17652178_ChIP-ChIP_JURKAT_Human2.95547008
10MYC_19079543_ChIP-ChIP_MESCs_Mouse2.65074472
11MYC_19030024_ChIP-ChIP_MESCs_Mouse2.63385188
12GABP_17652178_ChIP-ChIP_JURKAT_Human2.60512621
13MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse2.59989756
14AR_21909140_ChIP-Seq_LNCAP_Human2.58333160
15CHD1_19587682_ChIP-ChIP_MESCs_Mouse2.54840547
16EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse2.54389349
17CREB1_15753290_ChIP-ChIP_HEK293T_Human2.44355106
18MYBL2_22936984_ChIP-ChIP_MESCs_Mouse2.40645995
19MYC_18358816_ChIP-ChIP_MESCs_Mouse2.38577586
20RBPJ_22232070_ChIP-Seq_NCS_Mouse2.31792563
21NELFA_20434984_ChIP-Seq_ESCs_Mouse2.31260705
22ETS1_20019798_ChIP-Seq_JURKAT_Human2.30308138
23KDM5B_21448134_ChIP-Seq_MESCs_Mouse2.30202358
24SOX9_22984422_ChIP-ChIP_TESTIS_Rat2.29439057
25TP63_19390658_ChIP-ChIP_HaCaT_Human2.28672335
26JARID1A_20064375_ChIP-Seq_MESCs_Mouse2.25885871
27ZNF274_21170338_ChIP-Seq_K562_Hela2.24134301
28* XRN2_22483619_ChIP-Seq_HELA_Human2.22386263
29E2F1_21310950_ChIP-Seq_MCF-7_Human2.22006432
30MYCN_21190229_ChIP-Seq_SHEP-21N_Human2.18691520
31POU3F2_20337985_ChIP-ChIP_501MEL_Human2.07876343
32ELF1_17652178_ChIP-ChIP_JURKAT_Human2.02064852
33TTF2_22483619_ChIP-Seq_HELA_Human1.99263450
34ELK1_19687146_ChIP-ChIP_HELA_Human1.99190920
35HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human1.98475179
36YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.96598977
37VDR_23849224_ChIP-Seq_CD4+_Human1.91518257
38THAP11_20581084_ChIP-Seq_MESCs_Mouse1.85306500
39IGF1R_20145208_ChIP-Seq_DFB_Human1.85285648
40DCP1A_22483619_ChIP-Seq_HELA_Human1.85171310
41* FOXP3_21729870_ChIP-Seq_TREG_Human1.84835555
42E2F1_18555785_ChIP-Seq_MESCs_Mouse1.79432022
43PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse1.75452106
44VDR_22108803_ChIP-Seq_LS180_Human1.73163924
45MYCN_18555785_ChIP-Seq_MESCs_Mouse1.70562441
46SOX2_18555785_ChIP-Seq_MESCs_Mouse1.67469591
47E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse1.65241872
48ZFP57_27257070_Chip-Seq_ESCs_Mouse1.64818954
49SALL1_21062744_ChIP-ChIP_HESCs_Human1.62582438
50CIITA_25753668_ChIP-Seq_RAJI_Human1.61305009
51ZFP42_18358816_ChIP-ChIP_MESCs_Mouse1.59453316
52TAF15_26573619_Chip-Seq_HEK293_Human1.59003496
53FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse1.58919562
54NOTCH1_17114293_ChIP-ChIP_T-ALL_Human1.55813161
55GLI1_17442700_ChIP-ChIP_MESCs_Mouse1.54049489
56GABP_19822575_ChIP-Seq_HepG2_Human1.52776452
57CTBP2_25329375_ChIP-Seq_LNCAP_Human1.51172484
58POU5F1_16153702_ChIP-ChIP_HESCs_Human1.49694106
59CEBPD_23245923_ChIP-Seq_MEFs_Mouse1.47896391
60CCND1_20090754_ChIP-ChIP_RETINA_Mouse1.46724739
61HOXB4_20404135_ChIP-ChIP_EML_Mouse1.44937551
62P300_19829295_ChIP-Seq_ESCs_Human1.41994285
63GBX2_23144817_ChIP-Seq_PC3_Human1.40871179
64KLF4_19030024_ChIP-ChIP_MESCs_Mouse1.39101912
65PADI4_21655091_ChIP-ChIP_MCF-7_Human1.38838562
66POU5F1_18358816_ChIP-ChIP_MESCs_Mouse1.37639108
67POU5F1_18555785_ChIP-Seq_MESCs_Mouse1.37143232
68NANOG_18555785_ChIP-Seq_MESCs_Mouse1.32924629
69NR4A2_19515692_ChIP-ChIP_MN9D_Mouse1.31767271
70SOX2_16153702_ChIP-ChIP_HESCs_Human1.31641987
71YY1_21170310_ChIP-Seq_MESCs_Mouse1.31153863
72ZFX_18555785_ChIP-Seq_MESCs_Mouse1.31117982
73CTBP1_25329375_ChIP-Seq_LNCAP_Human1.27896673
74MYC_18940864_ChIP-ChIP_HL60_Human1.27753693
75MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human1.26643541
76ZFP322A_24550733_ChIP-Seq_MESCs_Mouse1.20549957
77FLI1_27457419_Chip-Seq_LIVER_Mouse1.17001568
78E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human1.16308682
79HOXD13_18407260_ChIP-ChIP_DEVELOPING-LIMBS_Mouse1.16075589
80EWS_26573619_Chip-Seq_HEK293_Human1.13983730
81CBX2_27304074_Chip-Seq_ESCs_Mouse1.13774699
82RCOR1_19997604_ChIP-ChIP_NEURONS_Mouse1.13031767
83KDM5A_27292631_Chip-Seq_BREAST_Human1.12671600
84SRF_21415370_ChIP-Seq_HL-1_Mouse1.12255952
85FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse1.10200262
86NANOG_16153702_ChIP-ChIP_HESCs_Human1.10135277
87SOX2_19030024_ChIP-ChIP_MESCs_Mouse1.07396326
88GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.04715290
89ASH2L_23239880_ChIP-Seq_MESCs_Mouse1.04196212
90TAL1_20887958_ChIP-Seq_HPC-7_Mouse1.04187198
91PDX1_19855005_ChIP-ChIP_MIN6_Mouse1.03794913
92MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse1.03549100
93SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse1.02632557
94FUS_26573619_Chip-Seq_HEK293_Human1.02322274
95SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.01673050
96RNF2_27304074_Chip-Seq_NSC_Mouse1.01540331
97ER_23166858_ChIP-Seq_MCF-7_Human1.01503908
98CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human1.01147037
99ERG_20887958_ChIP-Seq_HPC-7_Mouse0.99349273
100EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human0.98352296
101NANOG_21062744_ChIP-ChIP_HESCs_Human0.97543915
102PRDM5_23873026_ChIP-Seq_MEFs_Mouse0.96933122
103CNOT3_19339689_ChIP-ChIP_MESCs_Mouse0.96340408
104AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human0.95833928
105IRF1_19129219_ChIP-ChIP_H3396_Human0.95504520
106CBP_20019798_ChIP-Seq_JUKART_Human0.94744843
107IRF4_20064451_ChIP-Seq_CD4+T_Mouse0.94744843
108SOX9_26525672_Chip-Seq_HEART_Mouse0.92976885
109OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse0.91618483
110SOX17_20123909_ChIP-Seq_XEN_Mouse0.91348766
111UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human0.90820255
112TP53_22573176_ChIP-Seq_HFKS_Human0.90741271
113CREM_20920259_ChIP-Seq_GC1-SPG_Mouse0.88727803
114GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse0.87577072
115EGR1_19374776_ChIP-ChIP_THP-1_Human0.86546299
116FOXP2_21765815_ChIP-ChIP_NEURO2A_Mouse0.85916833
117SMAD3_21741376_ChIP-Seq_EPCs_Human0.85639897
118PCGF2_27294783_Chip-Seq_ESCs_Mouse0.85311814
119EZH2_27294783_Chip-Seq_NPCs_Mouse0.84502742
120SMAD2/3_21741376_ChIP-Seq_EPCs_Human0.84265632
121DMRT1_21621532_ChIP-ChIP_FETAL_Ovary0.83397333
122ELK1_22589737_ChIP-Seq_MCF10A_Human0.81822501
123ZFP281_18358816_ChIP-ChIP_MESCs_Mouse0.77548048
124SFPI1_20887958_ChIP-Seq_HPC-7_Mouse0.76961864
125CUX1_19635798_ChIP-ChIP_MULTIPLE_HUMAN_CANCER_TYPES_Human0.76197750
126DACH1_20351289_ChIP-Seq_MDA-MB-231_Human0.73960657
127ASXL1_24218140_ChIP-Seq_BMDM_Mouse0.71341106
128CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat0.69142903
129KLF4_18555785_ChIP-Seq_MESCs_Mouse0.68217304
130SMAD1_18555785_ChIP-Seq_MESCs_Mouse0.67786676
131GFI1B_20887958_ChIP-Seq_HPC-7_Mouse0.67759904
132TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat0.64949358
133BCL3_23251550_ChIP-Seq_MUSCLE_Mouse0.61132143
134TFEB_21752829_ChIP-Seq_HELA_Human0.60888769
135TRIM28_19339689_ChIP-ChIP_MESCs_Mouse0.59718645
136TCF3_18692474_ChIP-Seq_MEFs_Mouse0.57983075
137NANOG_18358816_ChIP-ChIP_MESCs_Mouse0.57580618

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0003693_abnormal_embryo_hatching4.00582882
2MP0010094_abnormal_chromosome_stability3.74276798
3MP0003111_abnormal_nucleus_morphology3.63802456
4MP0003077_abnormal_cell_cycle3.29225687
5MP0004957_abnormal_blastocyst_morpholog3.10808446
6MP0008057_abnormal_DNA_replication2.97349556
7MP0010030_abnormal_orbit_morphology2.76191207
8MP0008058_abnormal_DNA_repair2.75073651
9MP0000566_synostosis2.72406763
10MP0008932_abnormal_embryonic_tissue2.59291855
11MP0006292_abnormal_olfactory_placode2.53483007
12MP0008007_abnormal_cellular_replicative2.53302413
13MP0003123_paternal_imprinting2.51319823
14MP0003121_genomic_imprinting2.40123818
15MP0002638_abnormal_pupillary_reflex2.31849182
16MP0002938_white_spotting2.20056122
17MP0000372_irregular_coat_pigmentation2.18903687
18MP0003122_maternal_imprinting2.07294525
19MP0009053_abnormal_anal_canal1.93160141
20MP0000537_abnormal_urethra_morphology1.86943728
21MP0002102_abnormal_ear_morphology1.86413822
22MP0003937_abnormal_limbs/digits/tail_de1.80795613
23MP0005257_abnormal_intraocular_pressure1.80240783
24MP0003315_abnormal_perineum_morphology1.77775448
25MP0003880_abnormal_central_pattern1.73422195
26MP0000350_abnormal_cell_proliferation1.72027877
27MP0000049_abnormal_middle_ear1.70258950
28MP0003890_abnormal_embryonic-extraembry1.65209054
29MP0001293_anophthalmia1.63722537
30MP0001730_embryonic_growth_arrest1.62894644
31MP0005171_absent_coat_pigmentation1.58692335
32MP0002085_abnormal_embryonic_tissue1.56507637
33MP0003942_abnormal_urinary_system1.53308163
34MP0001697_abnormal_embryo_size1.49828919
35MP0008877_abnormal_DNA_methylation1.47452092
36MP0003786_premature_aging1.44880698
37MP0001672_abnormal_embryogenesis/_devel1.43420105
38MP0005380_embryogenesis_phenotype1.43420105
39MP0002084_abnormal_developmental_patter1.40164989
40MP0008789_abnormal_olfactory_epithelium1.39554773
41MP0003385_abnormal_body_wall1.39250815
42MP0003938_abnormal_ear_development1.38686708
43MP0002751_abnormal_autonomic_nervous1.33118101
44MP0005253_abnormal_eye_physiology1.32744835
45MP0003119_abnormal_digestive_system1.31388819
46MP0004133_heterotaxia1.30532181
47MP0003755_abnormal_palate_morphology1.29290312
48MP0003787_abnormal_imprinting1.27428549
49MP0009379_abnormal_foot_pigmentation1.27005974
50MP0001984_abnormal_olfaction1.24379223
51MP0003567_abnormal_fetal_cardiomyocyte1.24136632
52MP0003984_embryonic_growth_retardation1.24076302
53MP0001286_abnormal_eye_development1.22891400
54MP0002088_abnormal_embryonic_growth/wei1.21835918
55MP0004197_abnormal_fetal_growth/weight/1.21120954
56MP0003941_abnormal_skin_development1.20530799
57MP0002080_prenatal_lethality1.16768006
58MP0002249_abnormal_larynx_morphology1.16550319
59MP0000647_abnormal_sebaceous_gland1.16458040
60MP0005187_abnormal_penis_morphology1.14412563
61MP0001188_hyperpigmentation1.14071706
62MP0002932_abnormal_joint_morphology1.13600888
63MP0002282_abnormal_trachea_morphology1.13033220
64MP0000428_abnormal_craniofacial_morphol1.12571514
65MP0003861_abnormal_nervous_system1.11581446
66MP0002396_abnormal_hematopoietic_system1.11339837
67MP0003935_abnormal_craniofacial_develop1.10790721
68MP0009250_abnormal_appendicular_skeleto1.09704324
69MP0002233_abnormal_nose_morphology1.09115139
70MP0002736_abnormal_nociception_after1.08160611
71MP0003115_abnormal_respiratory_system1.06259017
72MP0000631_abnormal_neuroendocrine_gland1.04531833
73MP0002116_abnormal_craniofacial_bone1.03607181
74MP0009046_muscle_twitch1.03043550
75MP0008995_early_reproductive_senescence1.01340058
76MP0002210_abnormal_sex_determination1.00313609
77MP0001929_abnormal_gametogenesis0.99566813
78MP0000313_abnormal_cell_death0.99265986
79MP0002697_abnormal_eye_size0.97412427
80MP0001529_abnormal_vocalization0.96664723
81MP0002086_abnormal_extraembryonic_tissu0.95064679
82MP0002095_abnormal_skin_pigmentation0.94943585
83MP0010307_abnormal_tumor_latency0.93806446
84* MP0002111_abnormal_tail_morphology0.93775757
85MP0005551_abnormal_eye_electrophysiolog0.92997372
86MP0002234_abnormal_pharynx_morphology0.92923658
87MP0002184_abnormal_innervation0.92178819
88MP0000432_abnormal_head_morphology0.91849537
89MP0000569_abnormal_digit_pigmentation0.91489823
90MP0005084_abnormal_gallbladder_morpholo0.91488448
91MP0002177_abnormal_outer_ear0.91333761
92MP0002160_abnormal_reproductive_system0.90914723
93MP0006276_abnormal_autonomic_nervous0.90669318
94MP0001485_abnormal_pinna_reflex0.89598662
95MP0002114_abnormal_axial_skeleton0.89322187
96MP0002653_abnormal_ependyma_morphology0.88617247
97MP0005646_abnormal_pituitary_gland0.88396014
98MP0005408_hypopigmentation0.87824851
99MP0000613_abnormal_salivary_gland0.87026647
100MP0005394_taste/olfaction_phenotype0.86823832
101MP0005499_abnormal_olfactory_system0.86823832
102MP0006072_abnormal_retinal_apoptosis0.86657202
103MP0005389_reproductive_system_phenotype0.86390883
104MP0002092_abnormal_eye_morphology0.86202624
105MP0006054_spinal_hemorrhage0.85390916
106MP0003136_yellow_coat_color0.84522752
107MP0005195_abnormal_posterior_eye0.84323813
108MP0004808_abnormal_hematopoietic_stem0.83943975
109MP0000490_abnormal_crypts_of0.83511806
110MP0001145_abnormal_male_reproductive0.83304723
111MP0000427_abnormal_hair_cycle0.83113443
112MP0001486_abnormal_startle_reflex0.82994877
113MP0005248_abnormal_Harderian_gland0.82942377
114MP0003718_maternal_effect0.81942458
115MP0001324_abnormal_eye_pigmentation0.81344472
116MP0001919_abnormal_reproductive_system0.81122272
117MP0002752_abnormal_somatic_nervous0.80895253
118MP0001119_abnormal_female_reproductive0.80869831
119MP0002090_abnormal_vision0.79724226
120MP0003698_abnormal_male_reproductive0.79352089
121MP0002081_perinatal_lethality0.78812842
122MP0005076_abnormal_cell_differentiation0.77686749
123MP0000534_abnormal_ureter_morphology0.77090030
124MP0009697_abnormal_copulation0.76445490
125MP0009703_decreased_birth_body0.75579869
126MP0009672_abnormal_birth_weight0.75270551
127MP0002557_abnormal_social/conspecific_i0.75066258
128MP0002109_abnormal_limb_morphology0.74906316
129MP0005391_vision/eye_phenotype0.74772837
130MP0004147_increased_porphyrin_level0.74721304
131MP0004885_abnormal_endolymph0.73467856
132MP0000955_abnormal_spinal_cord0.72564985
133MP0002163_abnormal_gland_morphology0.71834797
134MP0000653_abnormal_sex_gland0.71645169
135MP0000778_abnormal_nervous_system0.70110623
136MP0000516_abnormal_urinary_system0.69230434
137MP0005367_renal/urinary_system_phenotyp0.69230434
138MP0003283_abnormal_digestive_organ0.68243617

Predicted human phenotypes

RankGene SetZ-score
1Chromosomal breakage induced by crosslinking agents (HP:0003221)3.51878750
2Abnormal lung lobation (HP:0002101)3.50033928
3Birth length less than 3rd percentile (HP:0003561)3.44369704
4Chromsome breakage (HP:0040012)3.43028068
5Patellar aplasia (HP:0006443)3.35376771
6Aplasia/Hypoplasia of the 4th metacarpal (HP:0010042)3.29477905
7Short 4th metacarpal (HP:0010044)3.29477905
8Nephroblastoma (Wilms tumor) (HP:0002667)3.25506179
9Aplasia/Hypoplasia of the fovea (HP:0008060)3.24275311
10Hypoplasia of the fovea (HP:0007750)3.24275311
11Aplasia/Hypoplasia of the patella (HP:0006498)3.16890802
12Embryonal renal neoplasm (HP:0011794)3.11762977
13Reticulocytopenia (HP:0001896)3.11079649
14Abnormality of the labia minora (HP:0012880)3.01758425
15Abnormal number of incisors (HP:0011064)2.98961636
16Abnormality of the fovea (HP:0000493)2.94531466
17Meckel diverticulum (HP:0002245)2.93671581
18Aplasia/Hypoplasia of the uvula (HP:0010293)2.88462123
19Abnormality of the ileum (HP:0001549)2.82482088
20Acute necrotizing encephalopathy (HP:0006965)2.78864373
21Abnormality of chromosome stability (HP:0003220)2.75234429
22Small intestinal stenosis (HP:0012848)2.74297684
23Duodenal stenosis (HP:0100867)2.74297684
24Ectopic kidney (HP:0000086)2.73353061
25Breast hypoplasia (HP:0003187)2.69852834
26True hermaphroditism (HP:0010459)2.67890361
27Facial hemangioma (HP:0000329)2.62299500
28Pancreatic cysts (HP:0001737)2.60629362
29Supernumerary spleens (HP:0009799)2.58526520
30Optic nerve hypoplasia (HP:0000609)2.58304550
31Abnormality of the preputium (HP:0100587)2.56766360
32Colon cancer (HP:0003003)2.53436443
33Short middle phalanx of the 5th finger (HP:0004220)2.52396731
34Acute encephalopathy (HP:0006846)2.52037145
35Progressive macrocephaly (HP:0004481)2.51899379
36Absent radius (HP:0003974)2.48707431
37Pancreatic fibrosis (HP:0100732)2.45640232
38Abnormality of midbrain morphology (HP:0002418)2.43615404
39Molar tooth sign on MRI (HP:0002419)2.43615404
40Aplasia/Hypoplasia of the sternum (HP:0006714)2.42928791
41Volvulus (HP:0002580)2.40494536
42Medulloblastoma (HP:0002885)2.38360549
43Absent forearm bone (HP:0003953)2.36522411
44Aplasia involving forearm bones (HP:0009822)2.36522411
45Degeneration of anterior horn cells (HP:0002398)2.36520708
46Abnormality of the anterior horn cell (HP:0006802)2.36520708
47Increased nuchal translucency (HP:0010880)2.35463569
48Triphalangeal thumb (HP:0001199)2.35286839
49Abnormal mitochondria in muscle tissue (HP:0008316)2.34810549
50Aplasia/Hypoplasia of the optic nerve (HP:0008058)2.34704024
51Abnormality of the duodenum (HP:0002246)2.34321598
52Mitochondrial inheritance (HP:0001427)2.30465712
53Increased CSF lactate (HP:0002490)2.26986673
54Atresia of the external auditory canal (HP:0000413)2.26059172
55Abnormality of cells of the erythroid lineage (HP:0012130)2.25972539
56Selective tooth agenesis (HP:0001592)2.25967465
57Impulsivity (HP:0100710)2.22966652
58Cortical dysplasia (HP:0002539)2.22147125
59Abnormality of the 4th metacarpal (HP:0010012)2.17251129
60Increased hepatocellular lipid droplets (HP:0006565)2.15534861
61Sloping forehead (HP:0000340)2.12976467
62Oligodactyly (hands) (HP:0001180)2.11303915
63Medial flaring of the eyebrow (HP:0010747)2.09749916
6411 pairs of ribs (HP:0000878)2.09004487
65Hypoplastic pelvis (HP:0008839)2.07190121
66Duplicated collecting system (HP:0000081)2.01744489
67Nephronophthisis (HP:0000090)1.99315940
68Oral leukoplakia (HP:0002745)1.99004753
69Hepatocellular necrosis (HP:0001404)1.98937621
70Abnormal number of erythroid precursors (HP:0012131)1.98777376
71Aplasia/Hypoplasia of the macula (HP:0008059)1.97948687
72Abnormality of the incisor (HP:0000676)1.97441193
73Renal duplication (HP:0000075)1.96839334
74Sclerocornea (HP:0000647)1.95712976
75Horseshoe kidney (HP:0000085)1.95291953
76Proximal placement of thumb (HP:0009623)1.94238529
77Short thumb (HP:0009778)1.93426581
78Myelodysplasia (HP:0002863)1.91242529
79Aplastic anemia (HP:0001915)1.90698289
80Neoplasm of the adrenal cortex (HP:0100641)1.90223401
81Lipid accumulation in hepatocytes (HP:0006561)1.89275378
82Aplasia/Hypoplasia of the tongue (HP:0010295)1.88894619
83Absent thumb (HP:0009777)1.87727877
84Gait imbalance (HP:0002141)1.87277764
85Aplasia/Hypoplasia of the sacrum (HP:0008517)1.86620806
86Hepatic necrosis (HP:0002605)1.86478954
87Facial cleft (HP:0002006)1.86386896
88Cerebral edema (HP:0002181)1.86181335
89Dandy-Walker malformation (HP:0001305)1.85948773
90Deviation of the thumb (HP:0009603)1.85760984
91Embryonal neoplasm (HP:0002898)1.85405029
92Clubbing of toes (HP:0100760)1.85329375
93Astigmatism (HP:0000483)1.84950503
94Congenital primary aphakia (HP:0007707)1.83791934
95Optic nerve coloboma (HP:0000588)1.83758216
96Abnormality of the renal collecting system (HP:0004742)1.83423225
97Gastrointestinal atresia (HP:0002589)1.83106754
98Abnormality of abdominal situs (HP:0011620)1.82892214
99Abdominal situs inversus (HP:0003363)1.82892214
100Tracheoesophageal fistula (HP:0002575)1.82251753
101Absent septum pellucidum (HP:0001331)1.81500417
102Aplasia/Hypoplasia affecting the retina (HP:0008061)1.80761060
103Carpal bone hypoplasia (HP:0001498)1.80336746
104Neoplasm of the pancreas (HP:0002894)1.79598650
105Intestinal atresia (HP:0011100)1.79186073
106Preaxial hand polydactyly (HP:0001177)1.79070351
107Abnormality of the carotid arteries (HP:0005344)1.78296888
108Aplasia/Hypoplasia affecting the fundus (HP:0008057)1.77922881
109Premature graying of hair (HP:0002216)1.77456109
110Broad distal phalanx of finger (HP:0009836)1.77104310
111Glioma (HP:0009733)1.76796897
112Aganglionic megacolon (HP:0002251)1.76583718
113Genital tract atresia (HP:0001827)1.76284213
114Septo-optic dysplasia (HP:0100842)1.75744619
115Bifid tongue (HP:0010297)1.74918905
116Methylmalonic acidemia (HP:0002912)1.74285572
117Hepatoblastoma (HP:0002884)1.73904420
118Anencephaly (HP:0002323)1.73573086
119High anterior hairline (HP:0009890)1.73344499
120Postaxial foot polydactyly (HP:0001830)1.72465949
121Small hand (HP:0200055)1.72373398
122Abnormality of chromosome segregation (HP:0002916)1.71426291
123Vaginal atresia (HP:0000148)1.70404270
124Lissencephaly (HP:0001339)1.70011772
125Bone marrow hypocellularity (HP:0005528)1.68668855
126Aqueductal stenosis (HP:0002410)1.67515799
127Aplasia/Hypoplasia of the middle phalanx of the 5th finger (HP:0009161)1.66488088
128Anophthalmia (HP:0000528)1.66102801
129Neoplasm of the adrenal gland (HP:0100631)1.65522488
130Postaxial hand polydactyly (HP:0001162)1.64199549
131Oligodactyly (HP:0012165)1.64022044
132Pallor (HP:0000980)1.63999516
133Renal hypoplasia (HP:0000089)1.63734666
134Abnormality of the metopic suture (HP:0005556)1.63493587
135Abnormality of the septum pellucidum (HP:0007375)1.63315107
136Abnormality of the renal medulla (HP:0100957)1.62910630
137Nephrogenic diabetes insipidus (HP:0009806)1.62797346
138Abnormality of the phalanges of the hallux (HP:0010057)1.62710601
139Syringomyelia (HP:0003396)1.62515235
140Spinal cord lesions (HP:0100561)1.62515235
141Microtia (HP:0008551)1.61421806
142Pendular nystagmus (HP:0012043)1.59928275
143Diastasis recti (HP:0001540)1.59819702
144Slender long bone (HP:0003100)1.58722123
145Abnormality of DNA repair (HP:0003254)1.58587226
146Missing ribs (HP:0000921)1.58211258
147Capillary hemangiomas (HP:0005306)1.58133449
148Neoplasm of the colon (HP:0100273)1.57692802
149Congenital, generalized hypertrichosis (HP:0004540)1.57258525
150Aplasia/Hypoplasia of the earlobes (HP:0009906)1.57047251
151Ependymoma (HP:0002888)1.56904607
152Rhabdomyosarcoma (HP:0002859)1.56548696
153Hyperglycinemia (HP:0002154)1.56073935
154Adrenal hypoplasia (HP:0000835)1.55399473
155Mesomelia (HP:0003027)1.55209107

Predicted kinase interactions (KEA)

RankGene SetZ-score
1BUB14.99749495
2CDC74.44431171
3WEE13.93327779
4SRPK13.33932872
5MKNK13.12497754
6TRIM282.94396236
7BRSK22.76854997
8EIF2AK12.53388850
9CCNB12.51639897
10WNK32.47133788
11NEK22.39629878
12MKNK22.31724118
13STK162.26417956
14TTK2.23501905
15VRK22.21274513
16PLK12.18939046
17VRK12.11885853
18PLK32.11660514
19PLK42.10911784
20TLK12.08652703
21BRSK12.00296901
22FRK1.98183628
23MAP3K41.90474058
24AURKB1.87467435
25MAP2K71.77213103
26DYRK31.72183395
27ATR1.69563641
28NEK11.63972289
29CDK71.61844316
30TNIK1.60405016
31MAP4K21.56359464
32PNCK1.52777769
33CHEK21.49144540
34PASK1.45546762
35EIF2AK31.44123592
36AURKA1.35617736
37EIF2AK21.34457459
38MARK11.32876441
39ZAK1.32410360
40BCR1.29385327
41ERBB31.24997470
42CHEK11.19575461
43UHMK11.17631608
44PBK1.14872987
45CDK81.13431926
46NUAK11.12081165
47STK41.08158079
48DYRK21.07576139
49CSNK1G21.07397412
50CLK11.04929313
51TSSK61.03413968
52MELK1.03362724
53LIMK11.02640190
54TGFBR11.00345634
55EPHB20.98334338
56MST40.95584380
57ACVR1B0.94555059
58ATM0.93722676
59YES10.93392030
60EPHA40.93048890
61SIK30.89589814
62MAP3K80.86556193
63CDK10.86130581
64RPS6KB20.80802580
65KSR10.80613857
66STK390.80511690
67TAF10.80436595
68CDK20.80311677
69MINK10.79693006
70BRAF0.77634834
71TESK20.76199066
72RPS6KA40.75346445
73GRK10.73955374
74BRD40.73895932
75FGFR20.73417000
76PINK10.69752193
77CDK40.66933713
78PAK40.66619826
79NME20.66599635
80STK38L0.65934827
81MAPK130.65111830
82CDK30.65101802
83CSNK2A10.63678423
84STK100.62853957
85PRKCG0.59980855
86RPS6KA50.59435760
87BMPR1B0.59225746
88CDK120.58318558
89PKN10.57889626
90PAK30.57787418
91INSRR0.55222182
92LATS10.55216403
93PLK20.54811338
94NME10.52868374
95CASK0.51070372
96CDK180.50688729
97STK30.50352033
98PAK10.47580544
99CSNK2A20.46964790
100OXSR10.46517788
101ERBB20.46381748
102BCKDK0.45076610
103WNK40.45008583
104PTK2B0.44935552
105CSNK1G30.43691735
106ADRBK20.42746622
107CDK150.42341074
108CDK11A0.40930050
109CDK140.40310936
110CSNK1G10.40080403
111FGFR10.38420558
112PRKCE0.37535137
113TESK10.36539869
114MARK30.33723391
115DYRK1B0.33584599
116PRKDC0.33471556
117AKT20.33232881
118ERBB40.32858541
119NEK90.32210307
120MAPK140.31321865
121PRKCI0.31038369
122PIM10.30219111
123CDK60.29380556
124CSNK1A10.29374187
125CSNK1D0.28645659
126AKT10.28411195
127CSNK1E0.27444713
128CSNK1A1L0.26789338
129ILK0.25950660
130DYRK1A0.24684116
131MAPK90.24682422
132NEK60.24431824
133GSK3B0.24331845
134AKT30.24321600

Predicted pathways (KEGG)

RankGene SetZ-score
1DNA replication_Homo sapiens_hsa030304.85991771
2Mismatch repair_Homo sapiens_hsa034304.28629349
3Spliceosome_Homo sapiens_hsa030403.63899706
4Homologous recombination_Homo sapiens_hsa034403.33029870
5Cell cycle_Homo sapiens_hsa041103.30372529
6Ribosome_Homo sapiens_hsa030103.08855292
7Base excision repair_Homo sapiens_hsa034103.07005439
8RNA polymerase_Homo sapiens_hsa030202.99803189
9Nucleotide excision repair_Homo sapiens_hsa034202.94755399
10RNA transport_Homo sapiens_hsa030132.86895579
11Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030082.71742753
12Fanconi anemia pathway_Homo sapiens_hsa034602.67925433
13Proteasome_Homo sapiens_hsa030502.61736875
14Pyrimidine metabolism_Homo sapiens_hsa002402.26581744
15Non-homologous end-joining_Homo sapiens_hsa034502.23040345
16Basal transcription factors_Homo sapiens_hsa030222.10567016
17mRNA surveillance pathway_Homo sapiens_hsa030152.09412436
18One carbon pool by folate_Homo sapiens_hsa006702.06132165
19RNA degradation_Homo sapiens_hsa030182.04690770
20Steroid biosynthesis_Homo sapiens_hsa001002.03789531
21Synthesis and degradation of ketone bodies_Homo sapiens_hsa000721.98888776
22Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001301.96469066
23Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009701.77781229
24p53 signaling pathway_Homo sapiens_hsa041151.71633303
25Systemic lupus erythematosus_Homo sapiens_hsa053221.60658945
26Propanoate metabolism_Homo sapiens_hsa006401.54622618
27Oocyte meiosis_Homo sapiens_hsa041141.44691561
28Basal cell carcinoma_Homo sapiens_hsa052171.42588896
29Purine metabolism_Homo sapiens_hsa002301.29986816
30Protein export_Homo sapiens_hsa030601.26606824
31Progesterone-mediated oocyte maturation_Homo sapiens_hsa049141.24626753
32Cysteine and methionine metabolism_Homo sapiens_hsa002701.15594580
33Ubiquitin mediated proteolysis_Homo sapiens_hsa041201.14892353
34Hedgehog signaling pathway_Homo sapiens_hsa043401.11345738
35Butanoate metabolism_Homo sapiens_hsa006501.09427143
36Epstein-Barr virus infection_Homo sapiens_hsa051691.08978537
37Vitamin B6 metabolism_Homo sapiens_hsa007501.08886553
38Maturity onset diabetes of the young_Homo sapiens_hsa049501.06929760
39Pyruvate metabolism_Homo sapiens_hsa006201.06452037
40Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006301.05939656
41Valine, leucine and isoleucine degradation_Homo sapiens_hsa002801.05151657
42Alcoholism_Homo sapiens_hsa050341.04794565
43MicroRNAs in cancer_Homo sapiens_hsa052061.03611255
44Hippo signaling pathway_Homo sapiens_hsa043901.03098585
45Nicotine addiction_Homo sapiens_hsa050331.01246898
46Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.95976805
47Viral carcinogenesis_Homo sapiens_hsa052030.95834905
48Huntingtons disease_Homo sapiens_hsa050160.93843655
49Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.90896405
50Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.88273944
51HTLV-I infection_Homo sapiens_hsa051660.88095647
52Folate biosynthesis_Homo sapiens_hsa007900.85057237
53Fatty acid elongation_Homo sapiens_hsa000620.84793827
54Parkinsons disease_Homo sapiens_hsa050120.83826267
55Selenocompound metabolism_Homo sapiens_hsa004500.78299232
56Wnt signaling pathway_Homo sapiens_hsa043100.77473548
57Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.75153321
58Herpes simplex infection_Homo sapiens_hsa051680.74782184
59Taurine and hypotaurine metabolism_Homo sapiens_hsa004300.74656637
60TGF-beta signaling pathway_Homo sapiens_hsa043500.73742379
61Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005340.72302287
62Colorectal cancer_Homo sapiens_hsa052100.70777443
63Small cell lung cancer_Homo sapiens_hsa052220.70014708
642-Oxocarboxylic acid metabolism_Homo sapiens_hsa012100.70013921
65Transcriptional misregulation in cancer_Homo sapiens_hsa052020.68148205
66Biosynthesis of amino acids_Homo sapiens_hsa012300.65774009
67Notch signaling pathway_Homo sapiens_hsa043300.65166833
68Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.63922434
69Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.61604027
70Oxidative phosphorylation_Homo sapiens_hsa001900.60453511
71Citrate cycle (TCA cycle)_Homo sapiens_hsa000200.55264768
72Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010400.55203063
73Pathways in cancer_Homo sapiens_hsa052000.54481677
74Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.53040702
75Carbon metabolism_Homo sapiens_hsa012000.51452717
76Phototransduction_Homo sapiens_hsa047440.51415098
77Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.49263678
78Adherens junction_Homo sapiens_hsa045200.49168103
79Cytosolic DNA-sensing pathway_Homo sapiens_hsa046230.48772107
80Nitrogen metabolism_Homo sapiens_hsa009100.46574822
81N-Glycan biosynthesis_Homo sapiens_hsa005100.46551533
82Peroxisome_Homo sapiens_hsa041460.46194541
83Taste transduction_Homo sapiens_hsa047420.45475752
84Axon guidance_Homo sapiens_hsa043600.43750511
85Melanoma_Homo sapiens_hsa052180.42652083
86Olfactory transduction_Homo sapiens_hsa047400.41694192
87Prostate cancer_Homo sapiens_hsa052150.40847829
88Collecting duct acid secretion_Homo sapiens_hsa049660.40736215
89Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.40651635
90Sulfur relay system_Homo sapiens_hsa041220.38588930
91GABAergic synapse_Homo sapiens_hsa047270.38562656
92Thyroid cancer_Homo sapiens_hsa052160.38535179
93Viral myocarditis_Homo sapiens_hsa054160.37307441
94Pentose and glucuronate interconversions_Homo sapiens_hsa000400.35228824
95Alzheimers disease_Homo sapiens_hsa050100.34551216
96Fatty acid metabolism_Homo sapiens_hsa012120.34514655
97Bladder cancer_Homo sapiens_hsa052190.33583045
98Regulation of autophagy_Homo sapiens_hsa041400.33239947
99Tight junction_Homo sapiens_hsa045300.31736314
100PI3K-Akt signaling pathway_Homo sapiens_hsa041510.31692946
101Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.31408779
102Chronic myeloid leukemia_Homo sapiens_hsa052200.31076047
103Tryptophan metabolism_Homo sapiens_hsa003800.30835419
104Melanogenesis_Homo sapiens_hsa049160.29675311
105Ascorbate and aldarate metabolism_Homo sapiens_hsa000530.29498509
106Hepatitis B_Homo sapiens_hsa051610.29281392
107Dopaminergic synapse_Homo sapiens_hsa047280.28075337
108Endometrial cancer_Homo sapiens_hsa052130.27354797
109beta-Alanine metabolism_Homo sapiens_hsa004100.26966350
110Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.23967279
111Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.23550863
112Antigen processing and presentation_Homo sapiens_hsa046120.23522524
113Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.23111737
114Retrograde endocannabinoid signaling_Homo sapiens_hsa047230.23052208
115Glutathione metabolism_Homo sapiens_hsa004800.21368652
116Bacterial invasion of epithelial cells_Homo sapiens_hsa051000.21222773
117Apoptosis_Homo sapiens_hsa042100.20392318
118Arginine and proline metabolism_Homo sapiens_hsa003300.20357678
119Arachidonic acid metabolism_Homo sapiens_hsa005900.20009910
120Sulfur metabolism_Homo sapiens_hsa009200.19961079
121Proteoglycans in cancer_Homo sapiens_hsa052050.19490834
122Non-small cell lung cancer_Homo sapiens_hsa052230.19042038
123FoxO signaling pathway_Homo sapiens_hsa040680.18991397
124Morphine addiction_Homo sapiens_hsa050320.18521932
125Caffeine metabolism_Homo sapiens_hsa002320.18498563
126Pentose phosphate pathway_Homo sapiens_hsa000300.17733245
127Steroid hormone biosynthesis_Homo sapiens_hsa001400.16264124
128Cardiac muscle contraction_Homo sapiens_hsa042600.15736198
129Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.13927145
130Pancreatic cancer_Homo sapiens_hsa052120.13725340
131Shigellosis_Homo sapiens_hsa051310.13452069
132Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005320.12354031
133Lysine degradation_Homo sapiens_hsa003100.12224072
134Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049320.11701951
135HIF-1 signaling pathway_Homo sapiens_hsa040660.11287616
136Primary immunodeficiency_Homo sapiens_hsa053400.10977810
137Renal cell carcinoma_Homo sapiens_hsa052110.10648782
138Regulation of actin cytoskeleton_Homo sapiens_hsa048100.07043993
139Gap junction_Homo sapiens_hsa045400.07038346
140Thyroid hormone signaling pathway_Homo sapiens_hsa049190.06861829
141Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054120.06220749
142Legionellosis_Homo sapiens_hsa051340.04324068
143Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054100.04048239
144Focal adhesion_Homo sapiens_hsa045100.03937565
145Rap1 signaling pathway_Homo sapiens_hsa040150.03483579
146Metabolic pathways_Homo sapiens_hsa011000.03445616
147Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.03328303
148Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.03202869
149SNARE interactions in vesicular transport_Homo sapiens_hsa041300.03077119
150ECM-receptor interaction_Homo sapiens_hsa045120.02956413

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