SH3BGRL3

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1neutrophil activation involved in immune response (GO:0002283)5.38876258
2antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G5.29677119
3respiratory burst (GO:0045730)5.05586698
4cytidine deamination (GO:0009972)4.92015652
5cytidine metabolic process (GO:0046087)4.92015652
6cytidine catabolic process (GO:0006216)4.92015652
7sequestering of actin monomers (GO:0042989)4.83474055
8pyrimidine ribonucleoside catabolic process (GO:0046133)4.34313947
9leukocyte aggregation (GO:0070486)4.27639007
10Arp2/3 complex-mediated actin nucleation (GO:0034314)4.13567896
11immunoglobulin mediated immune response (GO:0016064)4.12669002
12regulation of B cell receptor signaling pathway (GO:0050855)3.98975465
13positive regulation of antigen receptor-mediated signaling pathway (GO:0050857)3.91819554
14mast cell activation (GO:0045576)3.87370799
15antigen processing and presentation of endogenous antigen (GO:0019883)3.85075424
16antigen processing and presentation of endogenous peptide antigen (GO:0002483)3.79822608
17antigen processing and presentation of endogenous peptide antigen via MHC class I (GO:0019885)3.79822608
18regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:00450913.72882846
19regulation of antigen processing and presentation of peptide antigen (GO:0002583)3.68687965
20neutrophil activation (GO:0042119)3.65691787
21ribosomal small subunit assembly (GO:0000028)3.62766340
22granulocyte activation (GO:0036230)3.62044919
23response to peptidoglycan (GO:0032494)3.59669342
24viral transcription (GO:0019083)3.55669222
25cellular response to interferon-beta (GO:0035458)3.42828666
26positive regulation of interleukin-8 secretion (GO:2000484)3.40954630
27positive regulation of gamma-delta T cell activation (GO:0046645)3.40327277
28T cell migration (GO:0072678)3.39561798
29translational termination (GO:0006415)3.37999281
30regulation of T cell tolerance induction (GO:0002664)3.35340623
31defense response to protozoan (GO:0042832)3.32687703
32myeloid cell activation involved in immune response (GO:0002275)3.32195193
33negative regulation of T cell apoptotic process (GO:0070233)3.32109309
34cellular response to zinc ion (GO:0071294)3.30558124
35ribosomal small subunit biogenesis (GO:0042274)3.27820412
36antigen processing and presentation of exogenous peptide antigen via MHC class I (GO:0042590)3.26714957
37positive regulation by symbiont of host defense response (GO:0052509)3.26491475
38modulation by symbiont of host defense response (GO:0052031)3.26491475
39modulation by organism of immune response of other organism involved in symbiotic interaction (GO:003.26491475
40modulation by organism of defense response of other organism involved in symbiotic interaction (GO:03.26491475
41positive regulation by organism of defense response of other organism involved in symbiotic interact3.26491475
42modulation by symbiont of host immune response (GO:0052553)3.26491475
43regulation of natural killer cell mediated cytotoxicity (GO:0042269)3.23982169
44regulation of natural killer cell mediated immunity (GO:0002715)3.23982169
45B cell mediated immunity (GO:0019724)3.21920110
46regulation of regulatory T cell differentiation (GO:0045589)3.21480312
47actin nucleation (GO:0045010)3.21008453
48negative T cell selection (GO:0043383)3.20427285
49response to interferon-beta (GO:0035456)3.20192367
50myeloid dendritic cell activation (GO:0001773)3.19566938
51positive regulation of monocyte chemotaxis (GO:0090026)3.18213464
52regulation of B cell differentiation (GO:0045577)3.17182487
53positive regulation of T cell mediated cytotoxicity (GO:0001916)3.15701118
54pyrimidine nucleoside catabolic process (GO:0046135)3.12971856
55response to protozoan (GO:0001562)3.12153205
56SRP-dependent cotranslational protein targeting to membrane (GO:0006614)3.12094430
57leukocyte degranulation (GO:0043299)3.11479713
58positive regulation of macrophage differentiation (GO:0045651)3.11331695
59negative regulation of myeloid cell apoptotic process (GO:0033033)3.11130925
60antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent (GO:3.10704542
61antigen processing and presentation via MHC class Ib (GO:0002475)3.09851304
62cotranslational protein targeting to membrane (GO:0006613)3.09843946
63positive thymic T cell selection (GO:0045059)3.09113363
64DNA deamination (GO:0045006)3.07595258
65protein targeting to ER (GO:0045047)3.06330844
66negative regulation of interleukin-12 production (GO:0032695)3.06006179
67myeloid dendritic cell differentiation (GO:0043011)3.04428716
68type I interferon signaling pathway (GO:0060337)3.02755755
69cellular response to type I interferon (GO:0071357)3.02755755
70positive regulation of leukocyte mediated cytotoxicity (GO:0001912)3.02075360
71regulation of antigen receptor-mediated signaling pathway (GO:0050854)3.00142359
72regulation of T cell mediated cytotoxicity (GO:0001914)3.00004321
73positive regulation of mast cell activation (GO:0033005)2.99337034
74positive regulation of antigen processing and presentation (GO:0002579)2.98151021
75response to type I interferon (GO:0034340)2.97077797
76positive regulation of natural killer cell mediated immunity (GO:0002717)2.96999506
77regulation of tolerance induction (GO:0002643)2.96271683
78interferon-gamma-mediated signaling pathway (GO:0060333)2.94174943
79negative thymic T cell selection (GO:0045060)2.93811486
80regulation of leukocyte mediated cytotoxicity (GO:0001910)2.93294325
81protein localization to endoplasmic reticulum (GO:0070972)2.93233575
82cellular extravasation (GO:0045123)2.92120644
83establishment of protein localization to endoplasmic reticulum (GO:0072599)2.89896845
84regulation of interleukin-8 secretion (GO:2000482)2.89402886
85response to interleukin-15 (GO:0070672)2.88944324
86B cell receptor signaling pathway (GO:0050853)2.88894692
87T cell costimulation (GO:0031295)2.87754372
88positive regulation of B cell differentiation (GO:0045579)2.86873059
89regulation of gamma-delta T cell activation (GO:0046643)2.86090877
90lymphocyte costimulation (GO:0031294)2.84561791
91leukocyte mediated cytotoxicity (GO:0001909)2.84065125
92positive regulation of tolerance induction (GO:0002645)2.83194975
93detection of bacterium (GO:0016045)2.82691857
94positive regulation of lamellipodium assembly (GO:0010592)2.81727974
95positive regulation of interferon-alpha production (GO:0032727)2.81610046
96protein neddylation (GO:0045116)2.81246333
97lipoxygenase pathway (GO:0019372)2.80166840
98negative regulation of cell killing (GO:0031342)2.79116506
99negative regulation of leukocyte mediated cytotoxicity (GO:0001911)2.79116506
100regulation of T cell receptor signaling pathway (GO:0050856)2.78781728
101regulation of gamma-delta T cell differentiation (GO:0045586)2.77982319
102negative regulation of phagocytosis (GO:0050765)2.77686163
103translational elongation (GO:0006414)2.77540469
104viral life cycle (GO:0019058)2.76494361
105positive regulation of lymphocyte migration (GO:2000403)2.76343609
106thrombin receptor signaling pathway (GO:0070493)2.76010283
107positive regulation of alpha-beta T cell proliferation (GO:0046641)2.75900781
108mast cell degranulation (GO:0043303)2.75848198
109mast cell activation involved in immune response (GO:0002279)2.75848198
110positive T cell selection (GO:0043368)2.75630790
111detection of other organism (GO:0098543)2.74771101
112lipopolysaccharide-mediated signaling pathway (GO:0031663)2.74402370
113negative regulation of viral genome replication (GO:0045071)2.72492180
114regulation of interferon-alpha production (GO:0032647)2.71302566
115positive regulation of mast cell degranulation (GO:0043306)2.70888351
116positive regulation of mast cell activation involved in immune response (GO:0033008)2.70888351
117regulation of antigen processing and presentation (GO:0002577)2.70873842
118regulation of mast cell activation (GO:0033003)2.70771979
119cellular defense response (GO:0006968)2.70125445
120positive regulation of calcium-mediated signaling (GO:0050850)2.70096352
121regulation of T cell apoptotic process (GO:0070232)2.69713299
122neutrophil mediated immunity (GO:0002446)2.69611274
123regulation of hypersensitivity (GO:0002883)2.68900717
124regulation of platelet aggregation (GO:0090330)2.68225012
125positive regulation of cell killing (GO:0031343)2.67792059
126eosinophil chemotaxis (GO:0048245)2.67669379
127regulation of mast cell degranulation (GO:0043304)2.67063189
128regulation of T-helper 1 cell differentiation (GO:0045625)2.66042519
129cellular protein complex disassembly (GO:0043624)2.65968357
130negative regulation of interleukin-17 production (GO:0032700)2.65455262
131cellular response to interleukin-15 (GO:0071350)2.65287000
132positive regulation of natural killer cell mediated cytotoxicity (GO:0045954)2.65057649
133regulation of interferon-beta biosynthetic process (GO:0045357)2.64548864
134myeloid leukocyte activation (GO:0002274)2.64313725
135positive regulation of interleukin-2 biosynthetic process (GO:0045086)2.64153135
136T cell receptor signaling pathway (GO:0050852)2.63957838
137dendritic cell chemotaxis (GO:0002407)2.63703350
138negative regulation of leukocyte apoptotic process (GO:2000107)2.63594031
139negative regulation of stress fiber assembly (GO:0051497)2.63515961
140autophagic vacuole fusion (GO:0000046)2.63353811
141superoxide anion generation (GO:0042554)2.62968494
142regulation of cell killing (GO:0031341)2.62793703
143negative regulation of lymphocyte apoptotic process (GO:0070229)2.62241038
144membrane raft organization (GO:0031579)2.61445324
145phagosome maturation (GO:0090382)2.58367864
146regulation of alpha-beta T cell proliferation (GO:0046640)2.57187446
147regulation of lymphocyte migration (GO:2000401)2.57139070
148lymphocyte chemotaxis (GO:0048247)2.56761363
149monocyte chemotaxis (GO:0002548)2.56326400
150negative regulation of antigen receptor-mediated signaling pathway (GO:0050858)2.55725931
151regulation of protein heterodimerization activity (GO:0043497)2.55202090
152reactive oxygen species biosynthetic process (GO:1903409)2.52871095
153dendritic cell differentiation (GO:0097028)2.52724466

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1IRF8_21731497_ChIP-ChIP_J774_Mouse5.49935168
2IRF8_22096565_ChIP-ChIP_GC-B_Human5.42345968
3BP1_19119308_ChIP-ChIP_Hs578T_Human5.10819691
4IRF8_22096565_ChIP-ChIP_GC-B_Mouse4.21193252
5FOXP3_17237761_ChIP-ChIP_TREG_Mouse3.61613319
6MECOM_23826213_ChIP-Seq_KASUMI_Mouse3.61213475
7SPI1_22096565_ChIP-ChIP_GC-B_Mouse3.40635480
8SOX9_22984422_ChIP-ChIP_TESTIS_Rat3.36747863
9IRF8_27001747_Chip-Seq_BMDM_Mouse3.07368203
10STAT4_19710469_ChIP-ChIP_TH1__Mouse2.96394460
11MYB_21317192_ChIP-Seq_ERMYB_Mouse2.95997488
12SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse2.89725693
13SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse2.78300723
14STAT6_20620947_ChIP-Seq_CD4_POS_T_Human2.74054228
15* NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse2.66636895
16* RUNX1_20887958_ChIP-Seq_HPC-7_Mouse2.64341327
17* SPI1_23547873_ChIP-Seq_NB4_Human2.61371613
18FLI1_20887958_ChIP-Seq_HPC-7_Mouse2.54106588
19IRF1_21803131_ChIP-Seq_MONOCYTES_Human2.53147630
20ELF1_17652178_ChIP-ChIP_JURKAT_Human2.40518908
21STAT3_20064451_ChIP-Seq_CD4+T_Mouse2.36477809
22NOTCH1_17114293_ChIP-ChIP_T-ALL_Human2.33896106
23GABP_17652178_ChIP-ChIP_JURKAT_Human2.26771334
24* EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse2.22525140
25NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human2.21192729
26MYB_26560356_Chip-Seq_TH2_Human2.10291322
27VDR_21846776_ChIP-Seq_THP-1_Human2.00945910
28VDR_24763502_ChIP-Seq_THP-1_Human1.94318599
29EST1_17652178_ChIP-ChIP_JURKAT_Human1.92123960
30* RUNX1_22412390_ChIP-Seq_EML_Mouse1.89706066
31* MEIS1_20887958_ChIP-Seq_HPC-7_Mouse1.85267755
32CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human1.82480313
33RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human1.80535535
34* TAL1_20887958_ChIP-Seq_HPC-7_Mouse1.80438518
35BRD4_27068464_Chip-Seq_AML-cells_Mouse1.79451870
36* MAF_26560356_Chip-Seq_TH1_Human1.78693492
37LYL1_20887958_ChIP-Seq_HPC-7_Mouse1.77241558
38ASXL1_24218140_ChIP-Seq_BMDM_Mouse1.69649901
39JARID1A_20064375_ChIP-Seq_MESCs_Mouse1.67750718
40Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse1.67604230
41SFPI1_20887958_ChIP-Seq_HPC-7_Mouse1.66173511
42HOXB4_20404135_ChIP-ChIP_EML_Mouse1.66084364
43RUNX_20019798_ChIP-Seq_JUKART_Human1.64225658
44SCL_19346495_ChIP-Seq_HPC-7_Human1.63823965
45KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human1.61781457
46* MYB_26560356_Chip-Seq_TH1_Human1.60212449
47* FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse1.57347731
48CEBPB_20176806_ChIP-Seq_MACROPHAGES_Mouse1.55431502
49VDR_23849224_ChIP-Seq_CD4+_Human1.54063509
50BCL6_27268052_Chip-Seq_Bcells_Human1.53038053
51ETS1_20019798_ChIP-Seq_JURKAT_Human1.52686678
52ERG_20887958_ChIP-Seq_HPC-7_Mouse1.50675775
53CEBPB_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse1.50258690
54SPI1_23127762_ChIP-Seq_K562_Human1.46562986
55* LMO2_20887958_ChIP-Seq_HPC-7_Mouse1.46330887
56* UTX_26944678_Chip-Seq_JUKART_Human1.45564983
57E2F7_22180533_ChIP-Seq_HELA_Human1.44472857
58CREB1_15753290_ChIP-ChIP_HEK293T_Human1.42781472
59CEBPB_24764292_ChIP-Seq_MC3T3_Mouse1.42384868
60GATA2_21666600_ChIP-Seq_HMVEC_Human1.41512650
61CEBPB_20513432_ChIP-Seq_MACROPHAGES_Mouse1.38852331
62* ELK3_25401928_ChIP-Seq_HUVEC_Human1.37807846
63SCL_21571218_ChIP-Seq_MEGAKARYOCYTES_Human1.37606542
64ELK1_19687146_ChIP-ChIP_HELA_Human1.36753056
65RARG_19884340_ChIP-ChIP_MEFs_Mouse1.34380505
66SRY_22984422_ChIP-ChIP_TESTIS_Rat1.31468813
67GFI1B_20887958_ChIP-Seq_HPC-7_Mouse1.31399036
68STAT6_21828071_ChIP-Seq_BEAS2B_Human1.31128196
69PU_27001747_Chip-Seq_BMDM_Mouse1.30998681
70CEBPA_20513432_ChIP-Seq_MACROPHAGES_Mouse1.30861190
71SMAD_19615063_ChIP-ChIP_OVARY_Human1.30215029
72PU.1_20513432_ChIP-Seq_MACROPHAGES_Mouse1.29336886
73HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human1.29164750
74ELF1_20517297_ChIP-Seq_JURKAT_Human1.26930588
75* MAF_26560356_Chip-Seq_TH2_Human1.26014903
76SPI1_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse1.24761964
77BCOR_27268052_Chip-Seq_Bcells_Human1.22909229
78EGR1_19374776_ChIP-ChIP_THP-1_Human1.21399292
79GATA1_19941827_ChIP-Seq_MEL_Mouse1.21096456
80GATA2_22383799_ChIP-Seq_G1ME_Mouse1.19796550
81MYC_18555785_ChIP-Seq_MESCs_Mouse1.19709279
82DCP1A_22483619_ChIP-Seq_HELA_Human1.19192519
83MYC_22102868_ChIP-Seq_BL_Human1.18450741
84PU.1_20176806_ChIP-Seq_MACROPHAGES_Mouse1.16702674
85TCF21_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human1.15926000
86IKZF1_21737484_ChIP-ChIP_HCT116_Human1.15745547
87* GATA3_27048872_Chip-Seq_THYMUS_Human1.15269851
88SPI1_20517297_ChIP-Seq_HL60_Human1.15169572
89GATA1_22383799_ChIP-Seq_G1ME_Mouse1.14681553
90PPARG_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse1.14320516
91GATA3_26560356_Chip-Seq_TH2_Human1.14102251
92NOTCH1_21737748_ChIP-Seq_TLL_Human1.13407234
93PU.1_20513432_ChIP-Seq_Bcells_Mouse1.13316008
94FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse1.12985997
95MYC_18358816_ChIP-ChIP_MESCs_Mouse1.12931784
96CHD1_19587682_ChIP-ChIP_MESCs_Mouse1.12159973
97EBNA2_21746931_ChIP-Seq_IB4-LCL_Human1.10092479
98ATF3_23680149_ChIP-Seq_GBM1-GSC_Human1.09916350
99SRF_21415370_ChIP-Seq_HL-1_Mouse1.09895141
100FOXP3_21729870_ChIP-Seq_TREG_Human1.09043605
101* GATA2_20887958_ChIP-Seq_HPC-7_Mouse1.08321644
102STAT1_20625510_ChIP-Seq_HELA_Human1.08256378
103* E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human1.08235339
104ELK1_22589737_ChIP-Seq_MCF10A_Human1.07149303
105RBPJ_21746931_ChIP-Seq_IB4-LCL_Human1.05611081
106GATA1_19941826_ChIP-Seq_K562_Human1.04543571
107VDR_24787735_ChIP-Seq_THP-1_Human1.03000820
108XRN2_22483619_ChIP-Seq_HELA_Human1.02328017
109P300_27268052_Chip-Seq_Bcells_Human0.99401363
110* FLI1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.98965540
111* JUND_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human0.97053732
112HCFC1_20581084_ChIP-Seq_MESCs_Mouse0.94694706
113THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse0.94176429
114* LXR_22292898_ChIP-Seq_THP-1_Human0.93872495
115* TAL1_20566737_ChIP-Seq_PRIMARY_FETAL_LIVER_ERYTHROID_Mouse0.91974274
116PPARG_20176806_ChIP-Seq_MACROPHAGES_Mouse0.91762026
117GATA1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.91046304
118CUX1_19635798_ChIP-ChIP_MULTIPLE_HUMAN_CANCER_TYPES_Human0.90996155
119* JUN_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human0.89278384
120CTCF_27219007_Chip-Seq_ERYTHROID_Human0.88374223
121TFEB_21752829_ChIP-Seq_HELA_Human0.88204914
122YY1_22570637_ChIP-Seq_MALME-3M_Human0.87014878
123NFE2L2_22581777_ChIP-Seq_LYMPHOBLASTOID_Human0.86225160
124STAT5_23275557_ChIP-Seq_MAMMARY-EPITHELIUM_Mouse0.86050927
125CTCF_20526341_ChIP-Seq_ESCs_Human0.85542972
126CTCF_26484167_Chip-Seq_Bcells_Mouse0.83889685
127TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse0.82590841
128STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse0.82415922
129* E2F1_18555785_ChIP-Seq_MESCs_Mouse0.82235255
130HSF1_23293686_ChIP-Seq_STHDH_STRIATAL_Mouse0.81324260
131TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat0.80783042

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0001835_abnormal_antigen_presentation4.85039284
2MP0009785_altered_susceptibility_to3.86193520
3MP0005671_abnormal_response_to3.70456335
4MP0002148_abnormal_hypersensitivity_rea3.60072732
5MP0003436_decreased_susceptibility_to3.49094402
6MP0005000_abnormal_immune_tolerance3.32143257
7MP0005025_abnormal_response_to3.13316427
8MP0000685_abnormal_immune_system3.08315592
9MP0006082_CNS_inflammation2.97994825
10MP0002419_abnormal_innate_immunity2.97491669
11MP0001800_abnormal_humoral_immune2.85807794
12MP0001790_abnormal_immune_system2.85077506
13MP0005387_immune_system_phenotype2.85077506
14MP0002452_abnormal_antigen_presenting2.78679574
15MP0002723_abnormal_immune_serum2.76246423
16MP0002420_abnormal_adaptive_immunity2.67770163
17MP0001819_abnormal_immune_cell2.67312123
18MP0003303_peritoneal_inflammation2.61563234
19MP0003724_increased_susceptibility_to2.56985535
20MP0002405_respiratory_system_inflammati2.21962622
21MP0009333_abnormal_splenocyte_physiolog2.21412811
22MP0003763_abnormal_thymus_physiology2.20190826
23MP0002398_abnormal_bone_marrow2.10282323
24MP0001853_heart_inflammation2.09322218
25MP0004510_myositis2.08765710
26MP0005464_abnormal_platelet_physiology2.08382388
27MP0000716_abnormal_immune_system2.06054357
28MP0002166_altered_tumor_susceptibility2.05812000
29MP0002006_tumorigenesis2.00531777
30MP0003806_abnormal_nucleotide_metabolis1.87274256
31MP0001845_abnormal_inflammatory_respons1.79212587
32MP0001533_abnormal_skeleton_physiology1.72177060
33MP0000689_abnormal_spleen_morphology1.70918501
34MP0010155_abnormal_intestine_physiology1.69619440
35MP0002429_abnormal_blood_cell1.68544693
36MP0002722_abnormal_immune_system1.66918281
37MP0005310_abnormal_salivary_gland1.66596109
38MP0005058_abnormal_lysosome_morphology1.64157402
39MP0000343_altered_response_to1.61246092
40MP0004947_skin_inflammation1.61213226
41MP0000858_altered_metastatic_potential1.53034630
42MP0002396_abnormal_hematopoietic_system1.52474897
43MP0008004_abnormal_stomach_pH1.46264680
44MP0005174_abnormal_tail_pigmentation1.43883885
45MP0003448_altered_tumor_morphology1.43037210
46MP0008469_abnormal_protein_level1.39974236
47MP0001986_abnormal_taste_sensitivity1.37243966
48MP0003866_abnormal_defecation1.35535710
49MP0002933_joint_inflammation1.29266425
50MP0003172_abnormal_lysosome_physiology1.28873103
51MP0001851_eye_inflammation1.25039688
52MP0001873_stomach_inflammation1.24532446
53MP0000465_gastrointestinal_hemorrhage1.24015786
54MP0009379_abnormal_foot_pigmentation1.22135247
55MP0000703_abnormal_thymus_morphology1.18524589
56MP0006054_spinal_hemorrhage1.17760527
57MP0009764_decreased_sensitivity_to1.16646591
58MP0005397_hematopoietic_system_phenotyp1.16348116
59MP0001545_abnormal_hematopoietic_system1.16348116
60MP0005084_abnormal_gallbladder_morpholo1.15884969
61MP0002735_abnormal_chemical_nociception1.13570070
62MP0005083_abnormal_biliary_tract1.13542924
63MP0000490_abnormal_crypts_of1.13173642
64MP0009840_abnormal_foam_cell1.09540453
65MP0003186_abnormal_redox_activity1.04454615
66MP0003279_aneurysm1.03339698
67MP0002998_abnormal_bone_remodeling1.01925710
68MP0000015_abnormal_ear_pigmentation1.01571496
69MP0000372_irregular_coat_pigmentation0.99703628
70MP0003075_altered_response_to0.99006489
71MP0000920_abnormal_myelination0.98117487
72MP0003183_abnormal_peptide_metabolism0.96403430
73MP0005166_decreased_susceptibility_to0.95522533
74MP0002736_abnormal_nociception_after0.94379584
75MP0003045_fibrosis0.94143425
76MP0004808_abnormal_hematopoietic_stem0.90202186
77MP0003300_gastrointestinal_ulcer0.84046240
78MP0001663_abnormal_digestive_system0.82581072
79MP0005075_abnormal_melanosome_morpholog0.82571722
80MP0000604_amyloidosis0.81252039
81MP0009765_abnormal_xenobiotic_induced0.80378185
82MP0005023_abnormal_wound_healing0.79983376
83MP0005164_abnormal_response_to0.79486461
84MP0002163_abnormal_gland_morphology0.78926713
85MP0002019_abnormal_tumor_incidence0.78772287
86MP0001968_abnormal_touch/_nociception0.78732884
87MP0001958_emphysema0.78095848
88MP0002095_abnormal_skin_pigmentation0.75172907
89MP0005390_skeleton_phenotype0.73722717
90MP0001905_abnormal_dopamine_level0.73413381
91MP0003950_abnormal_plasma_membrane0.70880822
92MP0003638_abnormal_response/metabolism_0.69809666
93MP0008874_decreased_physiological_sensi0.66702195
94MP0001348_abnormal_lacrimal_gland0.66679657
95MP0004883_abnormal_blood_vessel0.66195557
96MP0005409_darkened_coat_color0.65483698
97MP0010386_abnormal_urinary_bladder0.65113582
98MP0009763_increased_sensitivity_to0.64929481
99MP0000249_abnormal_blood_vessel0.63071867
100MP0008438_abnormal_cutaneous_collagen0.62769849
101MP0008873_increased_physiological_sensi0.62685591
102MP0002138_abnormal_hepatobiliary_system0.61822019
103MP0001970_abnormal_pain_threshold0.61523890
104MP0009278_abnormal_bone_marrow0.60687156
105MP0004381_abnormal_hair_follicle0.60522812
106MP0000230_abnormal_systemic_arterial0.60392621
107MP0003656_abnormal_erythrocyte_physiolo0.60039270
108MP0003828_pulmonary_edema0.58301597
109MP0005410_abnormal_fertilization0.57897590
110MP0006036_abnormal_mitochondrial_physio0.56178892
111MP0002277_abnormal_respiratory_mucosa0.55489777
112MP0003566_abnormal_cell_adhesion0.54288895
113MP0008260_abnormal_autophagy0.53556767
114MP0002132_abnormal_respiratory_system0.52367876
115MP0003191_abnormal_cellular_cholesterol0.51396632
116MP0005165_increased_susceptibility_to0.50283350
117MP0002733_abnormal_thermal_nociception0.49833658
118MP0001542_abnormal_bone_strength0.49433336
119MP0003795_abnormal_bone_structure0.48444685
120MP0004782_abnormal_surfactant_physiolog0.43546079

Predicted human phenotypes

RankGene SetZ-score
1Recurrent abscess formation (HP:0002722)6.46492719
2Eczematoid dermatitis (HP:0000976)5.68515522
3Elevated erythrocyte sedimentation rate (HP:0003565)5.61163833
4Recurrent bacterial skin infections (HP:0005406)5.47244170
5Prolonged bleeding time (HP:0003010)4.72693497
6Myositis (HP:0100614)4.50024295
7Obstructive lung disease (HP:0006536)4.36917121
8Chronic obstructive pulmonary disease (HP:0006510)4.36917121
9Abnormality of macrophages (HP:0004311)4.25368362
10Stomatitis (HP:0010280)4.20102284
11Mediastinal lymphadenopathy (HP:0100721)4.13218311
12Recurrent gram-negative bacterial infections (HP:0005420)4.01212976
13Epistaxis (HP:0000421)3.96050108
14Recurrent skin infections (HP:0001581)3.87083158
15Vacuolated lymphocytes (HP:0001922)3.71907404
16Recurrent fungal infections (HP:0002841)3.70737278
17Abnormality of cells of the erythroid lineage (HP:0012130)3.47149081
18Menorrhagia (HP:0000132)3.42006594
19Chronic otitis media (HP:0000389)3.38661180
20Orchitis (HP:0100796)3.37444355
21Recurrent cutaneous fungal infections (HP:0011370)3.36174711
22Chronic mucocutaneous candidiasis (HP:0002728)3.36174711
23Meningitis (HP:0001287)3.33003083
24Gingival bleeding (HP:0000225)3.31784569
25Petechiae (HP:0000967)3.30188712
26Optic neuritis (HP:0100653)3.28705580
27Retrobulbar optic neuritis (HP:0100654)3.28705580
28Vasculitis (HP:0002633)3.27853882
29IgM deficiency (HP:0002850)3.27673159
30Abnormal platelet volume (HP:0011876)3.25009512
31Increased IgM level (HP:0003496)3.12000376
32Gingivitis (HP:0000230)3.11502768
33Recurrent bronchitis (HP:0002837)3.10968288
34Encephalitis (HP:0002383)3.10108489
35Aplastic anemia (HP:0001915)3.08876944
36Spontaneous hematomas (HP:0007420)3.07714392
37Primitive reflexes (palmomental, snout, glabellar) (HP:0002476)3.03063334
38Increased mean platelet volume (HP:0011877)2.94565944
39Recurrent viral infections (HP:0004429)2.94316428
40Hypergammaglobulinemia (HP:0010702)2.89260565
41Cellulitis (HP:0100658)2.89251237
42Increased neuronal autofluorescent lipopigment (HP:0002074)2.81095569
43Abnormal number of erythroid precursors (HP:0012131)2.78346174
44Interstitial pulmonary disease (HP:0006530)2.74372500
45Thyroiditis (HP:0100646)2.72299715
46IgG deficiency (HP:0004315)2.71938544
47Abnormal platelet function (HP:0011869)2.70910345
48Impaired platelet aggregation (HP:0003540)2.70910345
49Severe combined immunodeficiency (HP:0004430)2.70331766
50Agammaglobulinemia (HP:0004432)2.70030157
51Thrombocytosis (HP:0001894)2.69176949
52Increased cerebral lipofuscin (HP:0011813)2.66648725
53Abnormality of T cell number (HP:0011839)2.66635328
54Autoimmune thrombocytopenia (HP:0001973)2.60470938
55Recurrent pneumonia (HP:0006532)2.60136450
56Basal ganglia calcification (HP:0002135)2.56957626
57Abnormality of T cells (HP:0002843)2.56361722
58Chest pain (HP:0100749)2.54666772
59Leukocytosis (HP:0001974)2.54475754
60Exertional dyspnea (HP:0002875)2.52630198
61Hypoproteinemia (HP:0003075)2.52582420
62T lymphocytopenia (HP:0005403)2.51025590
63Urticaria (HP:0001025)2.50159634
64Pulmonary infiltrates (HP:0002113)2.47870501
65Lymphopenia (HP:0001888)2.45686217
66Episodic fever (HP:0001954)2.44979732
67Abnormality of cells of the lymphoid lineage (HP:0012140)2.44107430
68Abnormality of T cell physiology (HP:0011840)2.43490581
69Increased serum ferritin (HP:0003281)2.43228946
70Combined immunodeficiency (HP:0005387)2.41893819
71Joint swelling (HP:0001386)2.40646520
72Gastrointestinal infarctions (HP:0005244)2.39023721
73Poor head control (HP:0002421)2.38882755
74Reticulocytopenia (HP:0001896)2.36984059
75Purpura (HP:0000979)2.36880929
76Pustule (HP:0200039)2.36127813
77Hemoptysis (HP:0002105)2.35673557
78Chronic diarrhea (HP:0002028)2.35546392
79Abnormality of liposaccharide metabolism (HP:0010968)2.33311209
80Abnormality of glycosphingolipid metabolism (HP:0004343)2.33311209
81Abnormality of glycolipid metabolism (HP:0010969)2.33311209
82Panhypogammaglobulinemia (HP:0003139)2.33090337
83Sepsis (HP:0100806)2.32465957
84Autoimmune hemolytic anemia (HP:0001890)2.31343422
85Congenital nonbullous ichthyosiform erythroderma (HP:0007479)2.30843937
86Abnormality of eosinophils (HP:0001879)2.30067175
87Recurrent lower respiratory tract infections (HP:0002783)2.26366304
88Gastrointestinal stroma tumor (HP:0100723)2.25836463
89Nasal polyposis (HP:0100582)2.24936865
90Pallor (HP:0000980)2.20653698
91Increased hepatocellular lipid droplets (HP:0006565)2.19765397
92Parakeratosis (HP:0001036)2.18148370
93Abnormality of iron homeostasis (HP:0011031)2.17666979
94Osteomyelitis (HP:0002754)2.17362483
95Axonal loss (HP:0003447)2.17272331
96Eosinophilia (HP:0001880)2.16137948
97Hepatosplenomegaly (HP:0001433)2.14991296
98Increased IgE level (HP:0003212)2.14064078
99Abnormality of the prostate (HP:0008775)2.13249282
100Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688)2.13187347
101Systemic lupus erythematosus (HP:0002725)2.12792938
102Abnormal delayed hypersensitivity skin test (HP:0002963)2.07822245
103Keratoconjunctivitis sicca (HP:0001097)2.06488830
104Abnormality of the heme biosynthetic pathway (HP:0010472)2.04389323
105Pulmonary fibrosis (HP:0002206)2.03728327
106Amyloidosis (HP:0011034)2.03520855
107Gangrene (HP:0100758)2.03514775
108Renal Fanconi syndrome (HP:0001994)2.02886903
109Dysostosis multiplex (HP:0000943)2.01253895
110Granulocytopenia (HP:0001913)2.01194191
111Chronic sinusitis (HP:0011109)2.00204725
112Mitochondrial inheritance (HP:0001427)1.99662457
113Glomerulopathy (HP:0100820)1.98578935
114Skin ulcer (HP:0200042)1.97005150
115Hypertensive crisis (HP:0100735)1.96274974
116Agnosia (HP:0010524)1.95749152
117Muscle abnormality related to mitochondrial dysfunction (HP:0003800)1.95524650
118Abnormality of the nasal mucosa (HP:0000433)1.95433167
119Hyperlipoproteinemia (HP:0010980)1.95193670
120Arterial thrombosis (HP:0004420)1.94806704
121Decreased activity of mitochondrial respiratory chain (HP:0008972)1.94696842
122Abnormal activity of mitochondrial respiratory chain (HP:0011922)1.94696842
123Anorexia (HP:0002039)1.94074933
124Acute hepatic failure (HP:0006554)1.93676478
125B lymphocytopenia (HP:0010976)1.92220728
126Abnormality of B cell number (HP:0010975)1.92220728
1273-Methylglutaconic aciduria (HP:0003535)1.91476339
128Erythema (HP:0010783)1.91268971
129Inflammation of the large intestine (HP:0002037)1.91129113
130Keratoconjunctivitis (HP:0001096)1.91117659
131Periodontitis (HP:0000704)1.90909310
132Pulmonary embolism (HP:0002204)1.89065858
133Skin rash (HP:0000988)1.88925201
134Abnormality of the pleura (HP:0002103)1.84999909
135Abnormality of the pericardium (HP:0001697)1.84667414

Predicted kinase interactions (KEA)

RankGene SetZ-score
1MAP4K13.62340414
2RIPK43.60759003
3NME23.47184802
4BLK3.42957811
5MAP3K123.37160473
6PIM22.95641814
7TXK2.75774602
8IRAK42.54744493
9KIT2.50080426
10TBK12.48338006
11TESK22.30054227
12MAP3K142.22931007
13EIF2AK32.04925480
14MST42.01486759
15TYK21.99177432
16SYK1.93949170
17ZAP701.88815830
18IKBKE1.86476926
19TEC1.85198921
20KDR1.77674302
21BCKDK1.75313765
22PBK1.70000731
23BTK1.67792476
24EIF2AK11.64820125
25VRK21.63868086
26JAK31.63684764
27ARAF1.63507384
28IKBKB1.53514683
29TESK11.48509043
30FES1.41975839
31MAP3K31.40400127
32CSF1R1.39403624
33LCK1.32884626
34TGFBR21.31487854
35LYN1.29085096
36LIMK11.27403834
37BUB11.23644987
38ADRBK21.22391426
39TAOK21.19177941
40GRK61.17516890
41STK161.16991825
42PIK3CG1.14324795
43HCK1.11007277
44ERN11.07104196
45SIK31.05901487
46LRRK21.04135444
47ABL21.03852015
48ITK1.03745416
49IRAK31.03581886
50MAP3K131.00186048
51MAP3K110.99986202
52GRK70.99801415
53CLK10.98041209
54PTK2B0.97979387
55BMX0.96476101
56GRK50.92851110
57MATK0.91905960
58JAK10.87565184
59PIM10.86819688
60BMPR20.86169545
61CDK190.84744899
62NEK90.82309624
63CSK0.81842970
64STK100.79562782
65MYLK0.76215814
66ILK0.73571060
67VRK10.72536180
68MAP2K30.72480689
69PRKCD0.68543493
70BMPR1B0.67650540
71MUSK0.67256652
72FGR0.64464423
73MAPKAPK50.63535002
74PRKCQ0.62556075
75ADRBK10.61555596
76SCYL20.60695828
77TLK10.59588804
78LMTK20.59162972
79PAK40.58262135
80DAPK10.58002582
81TAOK10.57973050
82DAPK30.57173135
83EPHB10.51404628
84MAP3K50.51314254
85TRPM70.50694315
86RAF10.50595414
87ACVR1B0.48794965
88TNK20.47096178
89EIF2AK20.46935792
90NLK0.46124424
91PDK10.43758268
92MARK30.43652091
93ABL10.42885570
94NME10.42303103
95FLT30.41315130
96TAOK30.41313522
97CAMKK20.40088139
98MOS0.39201271
99MAPKAPK20.39140468
100YES10.38950463
101MAPK40.38480948
102TNIK0.38279720
103ROCK10.36447033
104MAP3K10.36249139
105RPS6KA40.36101768
106JAK20.34960504
107MAPKAPK30.34812122
108PAK10.34740796
109IGF1R0.34404741
110PRKD10.34093353
111PRKD20.34006085
112RPS6KA60.33854461
113NUAK10.33387287
114FYN0.32922693
115MAP4K20.31708647
116CHUK0.31544934
117MAP2K60.30997558
118CDK80.29632503
119INSR0.29296967
120RPS6KB20.27230257
121PRKG20.26856942
122STK40.26780475
123SRC0.22283082
124PRKCA0.21257857

Predicted pathways (KEGG)

RankGene SetZ-score
1Ribosome_Homo sapiens_hsa030103.20346646
2Proteasome_Homo sapiens_hsa030502.76992010
3Primary immunodeficiency_Homo sapiens_hsa053402.57836012
4Leishmaniasis_Homo sapiens_hsa051402.55734144
5Graft-versus-host disease_Homo sapiens_hsa053322.54768333
6Cytosolic DNA-sensing pathway_Homo sapiens_hsa046232.42741354
7Allograft rejection_Homo sapiens_hsa053302.42671012
8Asthma_Homo sapiens_hsa053102.17044424
9Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046502.11755485
10Oxidative phosphorylation_Homo sapiens_hsa001901.97974941
11Intestinal immune network for IgA production_Homo sapiens_hsa046721.92656680
12Inflammatory bowel disease (IBD)_Homo sapiens_hsa053211.88129556
13Hematopoietic cell lineage_Homo sapiens_hsa046401.82622462
14NF-kappa B signaling pathway_Homo sapiens_hsa040641.77262602
15Rheumatoid arthritis_Homo sapiens_hsa053231.76504845
16Osteoclast differentiation_Homo sapiens_hsa043801.71919178
17Antigen processing and presentation_Homo sapiens_hsa046121.71098524
18Pertussis_Homo sapiens_hsa051331.68387891
19Measles_Homo sapiens_hsa051621.68198661
20Toll-like receptor signaling pathway_Homo sapiens_hsa046201.64176330
21Parkinsons disease_Homo sapiens_hsa050121.61745298
22Tuberculosis_Homo sapiens_hsa051521.60896494
23B cell receptor signaling pathway_Homo sapiens_hsa046621.60014034
24RIG-I-like receptor signaling pathway_Homo sapiens_hsa046221.57376320
25Salmonella infection_Homo sapiens_hsa051321.57278794
26Shigellosis_Homo sapiens_hsa051311.56559639
27Malaria_Homo sapiens_hsa051441.50939159
28Phagosome_Homo sapiens_hsa041451.49937209
29NOD-like receptor signaling pathway_Homo sapiens_hsa046211.47627053
30Other glycan degradation_Homo sapiens_hsa005111.47183010
31DNA replication_Homo sapiens_hsa030301.45008966
32Legionellosis_Homo sapiens_hsa051341.38788578
33Protein export_Homo sapiens_hsa030601.38669580
34Pathogenic Escherichia coli infection_Homo sapiens_hsa051301.33849025
35Lysosome_Homo sapiens_hsa041421.33002569
36Autoimmune thyroid disease_Homo sapiens_hsa053201.32363601
37Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046661.32307376
38Alzheimers disease_Homo sapiens_hsa050101.28421359
39T cell receptor signaling pathway_Homo sapiens_hsa046601.22801843
40Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049321.22432807
41RNA polymerase_Homo sapiens_hsa030201.21487567
42Chagas disease (American trypanosomiasis)_Homo sapiens_hsa051421.18562465
43Cytokine-cytokine receptor interaction_Homo sapiens_hsa040601.17379762
44Chemokine signaling pathway_Homo sapiens_hsa040621.14687945
45Collecting duct acid secretion_Homo sapiens_hsa049661.13410890
46Fc epsilon RI signaling pathway_Homo sapiens_hsa046641.10895609
47Apoptosis_Homo sapiens_hsa042101.09154129
48Type I diabetes mellitus_Homo sapiens_hsa049401.06857736
49Herpes simplex infection_Homo sapiens_hsa051681.04863145
50SNARE interactions in vesicular transport_Homo sapiens_hsa041301.03928024
51Jak-STAT signaling pathway_Homo sapiens_hsa046301.03588953
52Toxoplasmosis_Homo sapiens_hsa051451.01099845
53Staphylococcus aureus infection_Homo sapiens_hsa051501.00954963
54Influenza A_Homo sapiens_hsa051641.00761878
55Huntingtons disease_Homo sapiens_hsa050160.99015307
56African trypanosomiasis_Homo sapiens_hsa051430.98387209
57Viral myocarditis_Homo sapiens_hsa054160.96462117
58TNF signaling pathway_Homo sapiens_hsa046680.93172971
59Sulfur metabolism_Homo sapiens_hsa009200.92185539
60Mismatch repair_Homo sapiens_hsa034300.90903292
61Hepatitis B_Homo sapiens_hsa051610.84741616
62Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.84451759
63Leukocyte transendothelial migration_Homo sapiens_hsa046700.81874039
64Homologous recombination_Homo sapiens_hsa034400.81867062
65Epstein-Barr virus infection_Homo sapiens_hsa051690.81573615
66Pyrimidine metabolism_Homo sapiens_hsa002400.80405691
67Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.80204224
68Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005320.78695318
69Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.77323063
70Base excision repair_Homo sapiens_hsa034100.75130936
71Vibrio cholerae infection_Homo sapiens_hsa051100.70468772
72Bacterial invasion of epithelial cells_Homo sapiens_hsa051000.70100656
73Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.68881267
74Arachidonic acid metabolism_Homo sapiens_hsa005900.68675047
75Glycosaminoglycan degradation_Homo sapiens_hsa005310.67078724
76Nucleotide excision repair_Homo sapiens_hsa034200.66147784
77Acute myeloid leukemia_Homo sapiens_hsa052210.65526405
78Platelet activation_Homo sapiens_hsa046110.57688645
79Regulation of autophagy_Homo sapiens_hsa041400.53961933
80Sphingolipid signaling pathway_Homo sapiens_hsa040710.53908474
81Sphingolipid metabolism_Homo sapiens_hsa006000.52147781
82Hepatitis C_Homo sapiens_hsa051600.52047434
83VEGF signaling pathway_Homo sapiens_hsa043700.51060127
84Neurotrophin signaling pathway_Homo sapiens_hsa047220.47342278
85AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049330.45875179
86Spliceosome_Homo sapiens_hsa030400.43140332
87Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.41067778
88Endocytosis_Homo sapiens_hsa041440.40124778
89Pancreatic cancer_Homo sapiens_hsa052120.40038153
90Glutathione metabolism_Homo sapiens_hsa004800.39744759
91Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.33912754
92Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.33766407
93Systemic lupus erythematosus_Homo sapiens_hsa053220.33220782
94p53 signaling pathway_Homo sapiens_hsa041150.32062317
95Fatty acid elongation_Homo sapiens_hsa000620.30780704
96Non-homologous end-joining_Homo sapiens_hsa034500.30764901
97HTLV-I infection_Homo sapiens_hsa051660.30532041
98Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.30274840
99Renin-angiotensin system_Homo sapiens_hsa046140.29957589
100Viral carcinogenesis_Homo sapiens_hsa052030.29927829
101Galactose metabolism_Homo sapiens_hsa000520.29793183
102Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.29307378
103Transcriptional misregulation in cancer_Homo sapiens_hsa052020.29303002
104Amoebiasis_Homo sapiens_hsa051460.28602798
105Regulation of actin cytoskeleton_Homo sapiens_hsa048100.28257106
106Pentose phosphate pathway_Homo sapiens_hsa000300.26580047
107alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.26000121
108Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.25151020
109Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.24732795
110Purine metabolism_Homo sapiens_hsa002300.20573499
111Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030080.20432253
112Nitrogen metabolism_Homo sapiens_hsa009100.20056833
113Drug metabolism - other enzymes_Homo sapiens_hsa009830.18615138
114Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047500.16931758
115Vascular smooth muscle contraction_Homo sapiens_hsa042700.11902024
116Complement and coagulation cascades_Homo sapiens_hsa046100.10392542

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