SERTAD4

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1metanephric mesenchyme development (GO:0072075)5.11262592
2kidney mesenchyme development (GO:0072074)4.79494317
3negative regulation of chondrocyte differentiation (GO:0032331)4.33375313
4neuron recognition (GO:0008038)4.01167337
5cornea development in camera-type eye (GO:0061303)3.94605942
6outer ear morphogenesis (GO:0042473)3.90638412
7bone trabecula formation (GO:0060346)3.86904017
8limb bud formation (GO:0060174)3.85837950
9collagen fibril organization (GO:0030199)3.82209817
10sequestering of extracellular ligand from receptor (GO:0035581)3.78877030
11chondrocyte proliferation (GO:0035988)3.72367465
12gamma-aminobutyric acid transport (GO:0015812)3.63351319
13axon extension (GO:0048675)3.59447162
14proximal/distal pattern formation (GO:0009954)3.53042116
15regulation of cardioblast proliferation (GO:0003264)3.40756773
16regulation of secondary heart field cardioblast proliferation (GO:0003266)3.40756773
17craniofacial suture morphogenesis (GO:0097094)3.38423744
18embryonic cranial skeleton morphogenesis (GO:0048701)3.36983037
19negative regulation of cartilage development (GO:0061037)3.34291293
20protein heterotrimerization (GO:0070208)3.30697834
21pyrimidine nucleobase catabolic process (GO:0006208)3.26977442
22sympathetic nervous system development (GO:0048485)3.22355601
23planar cell polarity pathway involved in neural tube closure (GO:0090179)3.19062484
24negative regulation of keratinocyte proliferation (GO:0010839)3.15794990
25regulation of establishment of planar polarity involved in neural tube closure (GO:0090178)3.11503335
26negative regulation of stem cell proliferation (GO:2000647)3.10335601
27central nervous system projection neuron axonogenesis (GO:0021952)3.09885184
28negative regulation of fatty acid transport (GO:2000192)3.05301458
29G-protein coupled receptor signaling pathway coupled to cGMP nucleotide second messenger (GO:00071993.03919668
30camera-type eye morphogenesis (GO:0048593)3.01522660
31presynaptic membrane assembly (GO:0097105)3.00875564
32middle ear morphogenesis (GO:0042474)2.98918358
33neuron projection extension (GO:1990138)2.95984634
34positive regulation of synapse assembly (GO:0051965)2.94723370
35dendrite morphogenesis (GO:0048813)2.92918568
36dermatan sulfate biosynthetic process (GO:0030208)2.92658893
37auditory behavior (GO:0031223)2.90154678
38cochlea morphogenesis (GO:0090103)2.87635062
39regulation of axon guidance (GO:1902667)2.86673761
40regulation of glycogen (starch) synthase activity (GO:2000465)2.86268175
41regulation of hippo signaling (GO:0035330)2.86146027
42cranial suture morphogenesis (GO:0060363)2.85579494
43epithelial to mesenchymal transition involved in endocardial cushion formation (GO:0003198)2.85535879
44chondrocyte development (GO:0002063)2.83069874
45myoblast fusion (GO:0007520)2.78634456
46regulation of cartilage development (GO:0061035)2.78056483
47spinal cord development (GO:0021510)2.76201743
48gonadal mesoderm development (GO:0007506)2.75376628
49neuron projection extension involved in neuron projection guidance (GO:1902284)2.75260074
50axon extension involved in axon guidance (GO:0048846)2.75260074
51mesenchyme morphogenesis (GO:0072132)2.75201786
52positive regulation of branching involved in ureteric bud morphogenesis (GO:0090190)2.74685067
53presynaptic membrane organization (GO:0097090)2.73427765
54embryonic body morphogenesis (GO:0010172)2.73253471
55negative regulation of glycogen biosynthetic process (GO:0045719)2.73172524
56limb development (GO:0060173)2.71965130
57appendage development (GO:0048736)2.71965130
58somite development (GO:0061053)2.71780620
59regulation of chondrocyte differentiation (GO:0032330)2.71756436
60nonmotile primary cilium assembly (GO:0035058)2.71704873
61hindlimb morphogenesis (GO:0035137)2.71356226
62extracellular fibril organization (GO:0043206)2.71278863
63negative regulation of dendrite morphogenesis (GO:0050774)2.70909911
64pharyngeal system development (GO:0060037)2.70341327
65embryonic hindlimb morphogenesis (GO:0035116)2.69565325
66hippo signaling (GO:0035329)2.68256059
67myoblast migration (GO:0051451)2.68054861
68negative regulation of axon guidance (GO:1902668)2.67637004
69cerebellar granule cell differentiation (GO:0021707)2.67347523
70urinary tract smooth muscle contraction (GO:0014848)2.67313039
71extracellular regulation of signal transduction (GO:1900115)2.65095234
72extracellular negative regulation of signal transduction (GO:1900116)2.65095234
73cell migration in hindbrain (GO:0021535)2.64664425
74regulation of heart morphogenesis (GO:2000826)2.64473561
75paraxial mesoderm development (GO:0048339)2.64133778
76embryonic digit morphogenesis (GO:0042733)2.64083179
77desmosome organization (GO:0002934)2.63910075
78regulation of synapse assembly (GO:0051963)2.63320517
79neuron cell-cell adhesion (GO:0007158)2.62129116
80nucleobase catabolic process (GO:0046113)2.61880037
81positive regulation of cartilage development (GO:0061036)2.61037337
82embryonic forelimb morphogenesis (GO:0035115)2.60688276
83negative regulation of axon extension involved in axon guidance (GO:0048843)2.60685852
84ionotropic glutamate receptor signaling pathway (GO:0035235)2.60625936
85insulin-like growth factor receptor signaling pathway (GO:0048009)2.60441875
86dermatan sulfate metabolic process (GO:0030205)2.60293354
87regulation of branching involved in ureteric bud morphogenesis (GO:0090189)2.59994869
88outflow tract septum morphogenesis (GO:0003148)2.59554645
89regulation of mesenchymal cell proliferation (GO:0010464)2.58928876
90postsynaptic membrane organization (GO:0001941)2.56974614
91mesenchyme development (GO:0060485)2.55796095
92axonal fasciculation (GO:0007413)2.55665387
93neural crest cell development (GO:0014032)2.55350392
94negative chemotaxis (GO:0050919)2.54984834
95ephrin receptor signaling pathway (GO:0048013)2.54838827
96myotube differentiation (GO:0014902)2.54560066
97peripheral nervous system neuron development (GO:0048935)2.54452644
98generation of neurons (GO:0048699)2.54411218
99organ induction (GO:0001759)2.54043167
100positive regulation of mesonephros development (GO:0061213)2.53900441
101positive regulation of mesenchymal cell proliferation (GO:0002053)2.53372240
102artery development (GO:0060840)2.52910180
103cerebral cortex radially oriented cell migration (GO:0021799)2.51296260
104calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules (GO:0016339)2.51023374
105embryonic skeletal joint morphogenesis (GO:0060272)2.50239054
106vocalization behavior (GO:0071625)2.50034266
107cartilage development involved in endochondral bone morphogenesis (GO:0060351)2.47856656
108cardiac right ventricle morphogenesis (GO:0003215)2.46576459
109suckling behavior (GO:0001967)2.45830478
110synapse assembly (GO:0007416)2.45203521
111regulation of mesonephros development (GO:0061217)2.44298606
112retinal ganglion cell axon guidance (GO:0031290)2.44231073
113regulation of cell proliferation involved in heart morphogenesis (GO:2000136)2.43836527
114body morphogenesis (GO:0010171)2.43451521
115otic vesicle formation (GO:0030916)2.42538575
116asymmetric protein localization (GO:0008105)2.42388458
117syncytium formation by plasma membrane fusion (GO:0000768)2.42114833
118cell aggregation (GO:0098743)2.40572618
119cartilage condensation (GO:0001502)2.40572618
120establishment or maintenance of monopolar cell polarity (GO:0061339)2.40439526
121establishment of monopolar cell polarity (GO:0061162)2.40439526
122neuron fate specification (GO:0048665)2.40031676
123central nervous system neuron axonogenesis (GO:0021955)2.39568976
124inner ear receptor stereocilium organization (GO:0060122)2.39459639
125heart valve morphogenesis (GO:0003179)2.39418962
126lateral sprouting from an epithelium (GO:0060601)2.38487103
127establishment of planar polarity (GO:0001736)2.38451688
128establishment of tissue polarity (GO:0007164)2.38451688
129mating behavior (GO:0007617)2.38324309
130mechanosensory behavior (GO:0007638)2.37462446
131synaptic transmission, glutamatergic (GO:0035249)2.36657273
132plasma membrane repair (GO:0001778)2.36548452
133embryonic appendage morphogenesis (GO:0035113)2.36543687
134embryonic limb morphogenesis (GO:0030326)2.36543687
135cranial nerve morphogenesis (GO:0021602)2.36465291
136regulation of axon extension involved in axon guidance (GO:0048841)2.36128600
137establishment of mitochondrion localization (GO:0051654)2.35910611
138lymphangiogenesis (GO:0001946)2.35734295
139endocardial cushion morphogenesis (GO:0003203)2.34815452
140forelimb morphogenesis (GO:0035136)2.34336453
141regulation of respiratory gaseous exchange by neurological system process (GO:0002087)2.34224457
142negative regulation of catenin import into nucleus (GO:0035414)2.34157065
143gastrulation with mouth forming second (GO:0001702)2.34136942
144sex differentiation (GO:0007548)2.33789792
145positive regulation of gastrulation (GO:2000543)2.33718623
146adenylate cyclase-activating dopamine receptor signaling pathway (GO:0007191)2.33198387
147regulation of organ formation (GO:0003156)2.32664886
148neuron remodeling (GO:0016322)2.32176860
149positive regulation of osteoblast differentiation (GO:0045669)2.32028118
150glial cell proliferation (GO:0014009)2.31989224
151heart valve formation (GO:0003188)2.31637911
152neuron migration (GO:0001764)2.31506397
153smooth muscle tissue development (GO:0048745)2.31485718
154developmental cell growth (GO:0048588)2.31036575
155protein localization to cilium (GO:0061512)2.30887940
156Wnt signaling pathway, planar cell polarity pathway (GO:0060071)2.30655622
157cell proliferation in forebrain (GO:0021846)2.30543288
158cell differentiation involved in kidney development (GO:0061005)2.30498146
159startle response (GO:0001964)2.30456718
160negative regulation of glycogen metabolic process (GO:0070874)2.30371133
161cell-cell signaling involved in cell fate commitment (GO:0045168)2.30337623
162cell proliferation involved in kidney development (GO:0072111)2.30290723
163regulation of establishment of planar polarity (GO:0090175)2.29898178
164dichotomous subdivision of an epithelial terminal unit (GO:0060600)2.29677322
165prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis (GO:0060522.29511110
166regulation of branching involved in prostate gland morphogenesis (GO:0060687)2.29291607
167keratinocyte development (GO:0003334)2.28594252
168myelination in peripheral nervous system (GO:0022011)2.28162323
169peripheral nervous system axon ensheathment (GO:0032292)2.28162323

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1RBPJ_22232070_ChIP-Seq_NCS_Mouse3.76558077
2TRIM28_21343339_ChIP-Seq_HEK293_Human2.86042122
3EZH2_22144423_ChIP-Seq_EOC_Human2.62499089
4TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat2.56844453
5* SUZ12_18555785_ChIP-Seq_MESCs_Mouse2.55529535
6GBX2_23144817_ChIP-Seq_PC3_Human2.45372304
7RNF2_18974828_ChIP-Seq_MESCs_Mouse2.41500290
8EZH2_18974828_ChIP-Seq_MESCs_Mouse2.41500290
9EED_16625203_ChIP-ChIP_MESCs_Mouse2.37493519
10GLI1_17442700_ChIP-ChIP_MESCs_Mouse2.35559411
11* EZH2_27304074_Chip-Seq_ESCs_Mouse2.30115676
12* SUZ12_18692474_ChIP-Seq_MESCs_Mouse2.28574726
13* SUZ12_18974828_ChIP-Seq_MESCs_Mouse2.28486552
14CEBPD_23245923_ChIP-Seq_MEFs_Mouse2.18853473
15SUZ12_16625203_ChIP-ChIP_MESCs_Mouse2.15825222
16* JARID2_20075857_ChIP-Seq_MESCs_Mouse2.15383663
17SUZ12_18692474_ChIP-Seq_MEFs_Mouse2.15009455
18JARID2_20064375_ChIP-Seq_MESCs_Mouse2.13723823
19WT1_19549856_ChIP-ChIP_CCG9911_Human2.12674231
20* RNF2_27304074_Chip-Seq_ESCs_Mouse2.09204477
21PHC1_16625203_ChIP-ChIP_MESCs_Mouse1.91483081
22ZNF217_24962896_ChIP-Seq_MCF-7_Human1.89480946
23* WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse1.83764827
24SMAD_19615063_ChIP-ChIP_OVARY_Human1.79749305
25PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.78131965
26ESR1_22446102_ChIP-Seq_UTERUS_Mouse1.73549093
27* MTF2_20144788_ChIP-Seq_MESCs_Mouse1.71215986
28SALL1_21062744_ChIP-ChIP_HESCs_Human1.70261913
29ESR1_20079471_ChIP-ChIP_T-47D_Human1.69075403
30* BMI1_23680149_ChIP-Seq_NPCS_Mouse1.69043436
31RNF2_16625203_ChIP-ChIP_MESCs_Mouse1.68723600
32AHR_22903824_ChIP-Seq_MCF-7_Human1.67963405
33TP53_18474530_ChIP-ChIP_U2OS_Human1.64538763
34CBX2_27304074_Chip-Seq_ESCs_Mouse1.63223847
35VDR_22108803_ChIP-Seq_LS180_Human1.62696643
36CDX2_19796622_ChIP-Seq_MESCs_Mouse1.62347593
37EP300_20729851_ChIP-Seq_FORBRAIN_MIDBRAIN_LIMB_HEART_Mouse1.60094233
38* EZH2_27294783_Chip-Seq_ESCs_Mouse1.57219570
39EP300_21415370_ChIP-Seq_HL-1_Mouse1.55695539
40* SUZ12_20075857_ChIP-Seq_MESCs_Mouse1.55077566
41CJUN_26792858_Chip-Seq_BT549_Human1.53213044
42CTBP2_25329375_ChIP-Seq_LNCAP_Human1.52057659
43* SUZ12_27294783_Chip-Seq_ESCs_Mouse1.51672275
44CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons1.51386930
45TP53_20018659_ChIP-ChIP_R1E_Mouse1.51117986
46NFE2L2_20460467_ChIP-Seq_MEFs_Mouse1.49148114
47NRF2_20460467_ChIP-Seq_MEFs_Mouse1.49148114
48* RING1B_27294783_Chip-Seq_NPCs_Mouse1.46235920
49* TCF3_18467660_ChIP-ChIP_MESCs_Mouse1.46171796
50TRIM28_17542650_ChIP-ChIP_NTERA2_Human1.45787681
51ARNT_22903824_ChIP-Seq_MCF-7_Human1.44096555
52AR_21572438_ChIP-Seq_LNCaP_Human1.44088801
53RARG_19884340_ChIP-ChIP_MEFs_Mouse1.43125363
54SMAD4_21799915_ChIP-Seq_A2780_Human1.43044008
55TCF4_18268006_ChIP-ChIP_LS174T_Human1.39585285
56PIAS1_25552417_ChIP-Seq_VCAP_Human1.37025962
57P300_19829295_ChIP-Seq_ESCs_Human1.36256032
58HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse1.35929896
59* RNF2_27304074_Chip-Seq_NSC_Mouse1.34045669
60TOP2B_26459242_ChIP-Seq_MCF-7_Human1.34021860
61FUS_26573619_Chip-Seq_HEK293_Human1.33158320
62CEBPD_21427703_ChIP-Seq_3T3-L1_Mouse1.32902445
63SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.32829235
64TP63_17297297_ChIP-ChIP_HaCaT_Human1.31507575
65REST_21632747_ChIP-Seq_MESCs_Mouse1.31418141
66TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.29703328
67POU5F1_26923725_Chip-Seq_MESODERM_Mouse1.29703328
68HOXD13_18407260_ChIP-ChIP_DEVELOPING-LIMBS_Mouse1.28787551
69ZFP281_18358816_ChIP-ChIP_MESCs_Mouse1.27860547
70TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse1.25830015
71PPARD_23176727_ChIP-Seq_KERATINOCYTES_Mouse1.24401524
72NR4A2_19515692_ChIP-ChIP_MN9D_Mouse1.24097580
73* RING1B_27294783_Chip-Seq_ESCs_Mouse1.24021569
74IGF1R_20145208_ChIP-Seq_DFB_Human1.23790231
75ISL1_27105846_Chip-Seq_CPCs_Mouse1.23552048
76BRD4_25478319_ChIP-Seq_HGPS_Human1.21770011
77* ZFP57_27257070_Chip-Seq_ESCs_Mouse1.21441766
78AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human1.21425414
79ZFP281_18757296_ChIP-ChIP_E14_Mouse1.19652110
80TAF15_26573619_Chip-Seq_HEK293_Human1.18432750
81SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.18277457
82SMAD4_19686287_ChIP-ChIP_HaCaT_Human1.16969081
83CTBP1_25329375_ChIP-Seq_LNCAP_Human1.16673458
84TFAP2C_20629094_ChIP-Seq_MCF-7_Human1.15803184
85* STAT3_24763339_ChIP-Seq_IMN-ESCs_Mouse1.15108062
86* MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse1.14633859
87TP63_19390658_ChIP-ChIP_HaCaT_Human1.14281453
88* TBX3_20139965_ChIP-Seq_ESCs_Mouse1.13260962
89* TBX3_20139965_ChIP-Seq_MESCs_Mouse1.13229982
90KLF4_25985364_ChIP-Seq_ATHEROSCLEROSIS_LESION_Mouse1.11853267
91YAP1_20516196_ChIP-Seq_MESCs_Mouse1.11349900
92DMRT1_23473982_ChIP-Seq_TESTES_Mouse1.11298374
93* WT1_25993318_ChIP-Seq_PODOCYTE_Human1.11128285
94NR3C1_23031785_ChIP-Seq_PC12_Mouse1.10206179
95FOXM1_26100407_CHIP-SEQ_Hek293_flp-in_Human1.09857834
96NR3C1_21868756_ChIP-Seq_MCF10A_Human1.09268841
97DROSHA_22980978_ChIP-Seq_HELA_Human1.08790077
98SOX9_24532713_ChIP-Seq_HFSC_Mouse1.08351138
99TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.08112860
100ZFP322A_24550733_ChIP-Seq_MESCs_Mouse1.07852054
101EWS_26573619_Chip-Seq_HEK293_Human1.07076518
102AR_25329375_ChIP-Seq_VCAP_Human1.06240537
103POU5F1_16153702_ChIP-ChIP_HESCs_Human1.06208978
104* POU3F2_20337985_ChIP-ChIP_501MEL_Human1.05448065
105SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.05201834
106SMAD3_21741376_ChIP-Seq_EPCs_Human1.04971617
107STAT3_23295773_ChIP-Seq_U87_Human1.04602038
108* OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.04567393
109CEBPB_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.03316729
110AR_19668381_ChIP-Seq_PC3_Human1.00499122
111GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.99891985
112RUNX2_22187159_ChIP-Seq_PCA_Human0.99848034
113FOXM1_26456572_ChIP-Seq_MCF-7_Human0.99704805
114* LMO2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.99282791
115SOX9_26525672_Chip-Seq_HEART_Mouse0.99269266
116TP53_16413492_ChIP-PET_HCT116_Human0.98883319
117JUN_21703547_ChIP-Seq_K562_Human0.97903339
118CEBPB_26923725_Chip-Seq_MESODERM_Mouse0.97733609
119ESR1_21235772_ChIP-Seq_MCF-7_Human0.97551630
120SOX2_21211035_ChIP-Seq_LN229_Gbm0.97379828
121OLIG2_26023283_ChIP-Seq_AINV15_Mouse0.96637891
122TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse0.93535844
123ZNF274_21170338_ChIP-Seq_K562_Hela0.92919915
124TCF4_23295773_ChIP-Seq_U87_Human0.90918634

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0005503_abnormal_tendon_morphology4.42745995
2MP0010030_abnormal_orbit_morphology3.91549760
3MP0008438_abnormal_cutaneous_collagen3.88438272
4MP0005275_abnormal_skin_tensile3.02527821
5MP0003385_abnormal_body_wall2.70228906
6MP0003122_maternal_imprinting2.45427813
7MP0009250_abnormal_appendicular_skeleto2.41349433
8MP0003705_abnormal_hypodermis_morpholog2.40427245
9MP0009053_abnormal_anal_canal2.40066464
10MP0008789_abnormal_olfactory_epithelium2.28166317
11MP0005499_abnormal_olfactory_system1.98404820
12MP0005394_taste/olfaction_phenotype1.98404820
13MP0000534_abnormal_ureter_morphology1.96514636
14MP0003755_abnormal_palate_morphology1.92401884
15MP0002249_abnormal_larynx_morphology1.92112592
16MP0000049_abnormal_middle_ear1.90446673
17MP0000537_abnormal_urethra_morphology1.88151521
18MP0000566_synostosis1.87134866
19MP0003942_abnormal_urinary_system1.85545316
20MP0003941_abnormal_skin_development1.81868710
21MP0005508_abnormal_skeleton_morphology1.78509246
22MP0003279_aneurysm1.77343376
23MP0004272_abnormal_basement_membrane1.76112771
24MP0001346_abnormal_lacrimal_gland1.69841928
25MP0000678_abnormal_parathyroid_gland1.69561897
26MP0002233_abnormal_nose_morphology1.68308763
27MP0005248_abnormal_Harderian_gland1.68272868
28MP0001299_abnormal_eye_distance/1.64833818
29MP0003937_abnormal_limbs/digits/tail_de1.61933869
30MP0002108_abnormal_muscle_morphology1.61690639
31MP0000762_abnormal_tongue_morphology1.61547745
32MP0000428_abnormal_craniofacial_morphol1.49219086
33MP0000013_abnormal_adipose_tissue1.47343255
34MP0003121_genomic_imprinting1.46269970
35MP0005257_abnormal_intraocular_pressure1.45305131
36MP0005423_abnormal_somatic_nervous1.38269141
37MP0002282_abnormal_trachea_morphology1.34682984
38MP0009780_abnormal_chondrocyte_physiolo1.34680185
39MP0000569_abnormal_digit_pigmentation1.34227753
40MP0001958_emphysema1.32980179
41MP0002060_abnormal_skin_morphology1.30521126
42MP0005171_absent_coat_pigmentation1.29041119
43MP0004133_heterotaxia1.28173226
44MP0004233_abnormal_muscle_weight1.27553464
45MP0002697_abnormal_eye_size1.25975427
46MP0000778_abnormal_nervous_system1.24779488
47MP0003935_abnormal_craniofacial_develop1.24613519
48MP0003787_abnormal_imprinting1.23277097
49MP0002177_abnormal_outer_ear1.23255382
50MP0000516_abnormal_urinary_system1.23215169
51MP0005367_renal/urinary_system_phenotyp1.23215169
52MP0002116_abnormal_craniofacial_bone1.21809458
53MP0005623_abnormal_meninges_morphology1.20734241
54MP0002932_abnormal_joint_morphology1.20386613
55MP0003119_abnormal_digestive_system1.20229351
56MP0002938_white_spotting1.19712625
57MP0001177_atelectasis1.17603769
58MP0000955_abnormal_spinal_cord1.16633079
59MP0004859_abnormal_synaptic_plasticity1.15729635
60MP0003123_paternal_imprinting1.14999640
61MP0004134_abnormal_chest_morphology1.14901086
62MP0004885_abnormal_endolymph1.14289840
63MP0002653_abnormal_ependyma_morphology1.13856349
64MP0001529_abnormal_vocalization1.13453197
65MP0002751_abnormal_autonomic_nervous1.11866169
66MP0001984_abnormal_olfaction1.10727257
67MP0000163_abnormal_cartilage_morphology1.08699262
68MP0003115_abnormal_respiratory_system1.08478794
69MP0004270_analgesia1.08144022
70MP0002896_abnormal_bone_mineralization1.07009863
71MP0002109_abnormal_limb_morphology1.06640677
72MP0000579_abnormal_nail_morphology1.06039525
73MP0009384_cardiac_valve_regurgitation1.05745895
74MP0002160_abnormal_reproductive_system1.04068892
75MP0004858_abnormal_nervous_system1.02718969
76MP0001849_ear_inflammation1.02695131
77MP0002572_abnormal_emotion/affect_behav1.01145555
78MP0002115_abnormal_skeleton_extremities1.00514532
79MP0001286_abnormal_eye_development0.99623236
80MP0002184_abnormal_innervation0.99210534
81MP0004142_abnormal_muscle_tone0.98833726
82MP0003315_abnormal_perineum_morphology0.97721999
83MP0000432_abnormal_head_morphology0.96693581
84MP0002882_abnormal_neuron_morphology0.95867404
85MP0001270_distended_abdomen0.95233863
86MP0003890_abnormal_embryonic-extraembry0.94297653
87MP0003938_abnormal_ear_development0.94004227
88MP0009046_muscle_twitch0.93784399
89MP0002877_abnormal_melanocyte_morpholog0.93585171
90MP0000647_abnormal_sebaceous_gland0.93578330
91MP0002272_abnormal_nervous_system0.91783314
92MP0002168_other_aberrant_phenotype0.91216514
93MP0002152_abnormal_brain_morphology0.89738038
94MP0000026_abnormal_inner_ear0.88442788
95MP0003880_abnormal_central_pattern0.88326391
96MP0005646_abnormal_pituitary_gland0.87729388
97MP0000733_abnormal_muscle_development0.86437576
98MP0002752_abnormal_somatic_nervous0.85931346
99MP0002114_abnormal_axial_skeleton0.85930334
100MP0001340_abnormal_eyelid_morphology0.84989772
101MP0002557_abnormal_social/conspecific_i0.84690570
102MP0001293_anophthalmia0.83488352
103MP0001879_abnormal_lymphatic_vessel0.83153872
104MP0000383_abnormal_hair_follicle0.82840002
105MP0005187_abnormal_penis_morphology0.82566327
106MP0001324_abnormal_eye_pigmentation0.82435021
107MP0002736_abnormal_nociception_after0.81767415
108MP0005197_abnormal_uvea_morphology0.80193653
109MP0002822_catalepsy0.78878915
110MP0003635_abnormal_synaptic_transmissio0.78374358
111MP0002102_abnormal_ear_morphology0.78277674
112MP0000631_abnormal_neuroendocrine_gland0.77866789
113MP0002295_abnormal_pulmonary_circulatio0.77787130
114MP0002081_perinatal_lethality0.77159258
115MP0000767_abnormal_smooth_muscle0.76039369
116MP0000751_myopathy0.75942120
117MP0002113_abnormal_skeleton_development0.75540007
118MP0002063_abnormal_learning/memory/cond0.75387851
119MP0003283_abnormal_digestive_organ0.75162460
120MP0006276_abnormal_autonomic_nervous0.74942263
121MP0002734_abnormal_mechanical_nocicepti0.72082135
122MP0006292_abnormal_olfactory_placode0.71190755
123MP0001188_hyperpigmentation0.71119280
124MP0000613_abnormal_salivary_gland0.71022248
125MP0002234_abnormal_pharynx_morphology0.70931464
126MP0000467_abnormal_esophagus_morphology0.70401238
127MP0003861_abnormal_nervous_system0.69489682
128MP0002254_reproductive_system_inflammat0.69407009
129MP0002735_abnormal_chemical_nociception0.69041609
130MP0002111_abnormal_tail_morphology0.69009611
131MP0010234_abnormal_vibrissa_follicle0.68701372

Predicted human phenotypes

RankGene SetZ-score
1Protrusio acetabuli (HP:0003179)4.12465585
2Premature rupture of membranes (HP:0001788)3.76035039
3Shallow orbits (HP:0000586)3.42382912
4Short 4th metacarpal (HP:0010044)3.38130463
5Aplasia/Hypoplasia of the 4th metacarpal (HP:0010042)3.38130463
6Asymmetry of the thorax (HP:0001555)3.34775738
7Atrophic scars (HP:0001075)3.10819356
8Abnormality of dentin (HP:0010299)2.97717755
9Follicular hyperkeratosis (HP:0007502)2.96841845
10Popliteal pterygium (HP:0009756)2.78012990
11Abnormality of the 4th metacarpal (HP:0010012)2.77712288
12Midline defect of the nose (HP:0004122)2.60748625
13Morphological abnormality of the middle ear (HP:0008609)2.59907456
14Soft skin (HP:0000977)2.59616931
15Microglossia (HP:0000171)2.59304234
16Bladder diverticulum (HP:0000015)2.58255556
17Broad metatarsal (HP:0001783)2.56817059
18Fragile skin (HP:0001030)2.54652001
19Ankle contracture (HP:0006466)2.53668181
20Wrist flexion contracture (HP:0001239)2.52675494
21Mesomelia (HP:0003027)2.51820443
22Infantile muscular hypotonia (HP:0008947)2.44961614
23Cutaneous finger syndactyly (HP:0010554)2.42865681
24Abnormality of the phalanges of the hallux (HP:0010057)2.42710053
25True hermaphroditism (HP:0010459)2.34444295
26Neonatal short-limb short stature (HP:0008921)2.27613375
27Overgrowth (HP:0001548)2.27050263
28Spinal rigidity (HP:0003306)2.22328122
29Aortic dissection (HP:0002647)2.21576156
30Bell-shaped thorax (HP:0001591)2.20635880
31Wormian bones (HP:0002645)2.19811793
32Hepatoblastoma (HP:0002884)2.16893706
33Lip pit (HP:0100267)2.15779934
34Pancreatic fibrosis (HP:0100732)2.15001938
35Abnormality of the aortic arch (HP:0012303)2.09757019
36Type 1 muscle fiber predominance (HP:0003803)2.09520052
37Vascular tortuosity (HP:0004948)2.08185158
38Concave nail (HP:0001598)2.06786718
39Hypoplastic pelvis (HP:0008839)2.06268429
40Synostosis involving the elbow (HP:0003938)2.05749371
41Humeroradial synostosis (HP:0003041)2.05749371
42Abnormality of the nasal septum (HP:0000419)2.05025871
43Calcaneovalgus deformity (HP:0001848)2.05015838
44Syringomyelia (HP:0003396)2.04196108
45Spinal cord lesions (HP:0100561)2.04196108
46Cutaneous syndactyly (HP:0012725)2.03333169
47Dilatation of the ascending aorta (HP:0005111)2.03021830
48Abnormality of the distal phalanx of the thumb (HP:0009617)2.00147687
49Wide anterior fontanel (HP:0000260)1.99767997
50Gait imbalance (HP:0002141)1.97705321
51Aortic aneurysm (HP:0004942)1.96716248
52Keratoconus (HP:0000563)1.96209792
53Increased corneal curvature (HP:0100692)1.96209792
54Deviation of the hallux (HP:0010051)1.96135123
55Coronal craniosynostosis (HP:0004440)1.95571388
56Molar tooth sign on MRI (HP:0002419)1.93903230
57Abnormality of midbrain morphology (HP:0002418)1.93903230
58Abnormality of the distal phalanges of the toes (HP:0010182)1.92866765
59Aplasia/Hypoplasia of the tongue (HP:0010295)1.90105646
60Failure to thrive in infancy (HP:0001531)1.89499599
61Natal tooth (HP:0000695)1.88482360
62Short nail (HP:0001799)1.87241187
63Genetic anticipation (HP:0003743)1.86634458
64Broad ribs (HP:0000885)1.83256984
65Mildly elevated creatine phosphokinase (HP:0008180)1.83061465
66Bowel diverticulosis (HP:0005222)1.82561011
67Smooth philtrum (HP:0000319)1.82260327
68Hypoplastic labia majora (HP:0000059)1.81345567
69Chorioretinal atrophy (HP:0000533)1.81235088
70Aplasia/Hypoplasia of the pubic bone (HP:0009104)1.80418311
71Pancreatic cysts (HP:0001737)1.79716250
72Aplasia cutis congenita (HP:0001057)1.79603479
73Papillary thyroid carcinoma (HP:0002895)1.79388384
74Deformed tarsal bones (HP:0008119)1.78887826
75Subacute progressive viral hepatitis (HP:0006572)1.78617103
76Broad long bones (HP:0005622)1.78344829
77Abnormality of the labia majora (HP:0012881)1.77680653
78Pterygium (HP:0001059)1.77533546
79Abnormality of the parietal bone (HP:0002696)1.77411581
80Broad toe (HP:0001837)1.76583234
81Hallux valgus (HP:0001822)1.76469381
82Nephronophthisis (HP:0000090)1.76281932
83Cervical subluxation (HP:0003308)1.75892764
84Joint laxity (HP:0001388)1.75658542
85Bronchomalacia (HP:0002780)1.75489544
86Arterial tortuosity (HP:0005116)1.75146056
87Abnormality of the ischium (HP:0003174)1.73831613
88Abnormality of the middle phalanges of the toes (HP:0010183)1.73229650
89Buphthalmos (HP:0000557)1.73067798
90Blue sclerae (HP:0000592)1.72757749
91Narrow nasal bridge (HP:0000446)1.71674665
92Abnormal number of incisors (HP:0011064)1.71514656
93Absent phalangeal crease (HP:0006109)1.71401749
94Lower limb amyotrophy (HP:0007210)1.71180977
95Poor coordination (HP:0002370)1.70954164
96Pheochromocytoma (HP:0002666)1.70950091
97Tarsal synostosis (HP:0008368)1.70856452
98Hyperextensible skin (HP:0000974)1.69788347
99Increased number of teeth (HP:0011069)1.67935288
100Megalencephaly (HP:0001355)1.67577089
101Genital tract atresia (HP:0001827)1.66753752
102Absent eyebrow (HP:0002223)1.66335206
103Down-sloping shoulders (HP:0200021)1.66097453
104Abnormality of the proximal phalanges of the hand (HP:0009834)1.65762036
105Hypoplasia of the maxilla (HP:0000327)1.65700560
106Congenital primary aphakia (HP:0007707)1.64405405
107Vaginal atresia (HP:0000148)1.63828313
108Symphalangism affecting the phalanges of the hand (HP:0009773)1.63473357
109Camptodactyly of toe (HP:0001836)1.63459396
110Increased connective tissue (HP:0009025)1.63436631
111Scrotal hypoplasia (HP:0000046)1.62527727
112Sclerocornea (HP:0000647)1.62030682
113Hip dysplasia (HP:0001385)1.61918725
114Neoplasm of the heart (HP:0100544)1.61838797
115Limited hip movement (HP:0008800)1.61663327
116Anencephaly (HP:0002323)1.60879594
117Fibular aplasia (HP:0002990)1.60697631
118Protruding ear (HP:0000411)1.60649590
119Preauricular pit (HP:0004467)1.60554831
120Periauricular skin pits (HP:0100277)1.60554831
121Cystic liver disease (HP:0006706)1.60078274
122Biconcave vertebral bodies (HP:0004586)1.59661586
123Broad phalanx (HP:0006009)1.59394862
124Radial bowing (HP:0002986)1.58989548
125Genu recurvatum (HP:0002816)1.58410512
126Aplasia/Hypoplasia of the phalanges of the toes (HP:0010173)1.58376860
127Exostoses (HP:0100777)1.57530576
128Medial flaring of the eyebrow (HP:0010747)1.57156496
129Hypoplastic ischia (HP:0003175)1.57138716
130Aplasia involving bones of the extremities (HP:0009825)1.57016253
131Aplasia involving bones of the upper limbs (HP:0009823)1.57016253
132Aplasia of the phalanges of the hand (HP:0009802)1.57016253
133Mitral valve prolapse (HP:0001634)1.56789535
134Short foot (HP:0001773)1.56292913
135Scapular winging (HP:0003691)1.55970780
136Broad finger (HP:0001500)1.55334094
137Aplasia/Hypoplasia of the lens (HP:0008063)1.55265696
138Turricephaly (HP:0000262)1.55130834
139Synostosis involving bones of the lower limbs (HP:0009138)1.54785275
140Synostosis involving bones of the feet (HP:0009140)1.54785275
141Aplasia/Hypoplasia of the 1st metacarpal (HP:0010026)1.54527290
142Short 1st metacarpal (HP:0010034)1.54527290
143Abnormal ciliary motility (HP:0012262)1.53529034
144Aplasia/Hypoplasia of the patella (HP:0006498)1.53398481
145Aqueductal stenosis (HP:0002410)1.53220250
146Broad thumb (HP:0011304)1.53030404
147Long clavicles (HP:0000890)1.52939004
148Mitral regurgitation (HP:0001653)1.52724773
149Fibular hypoplasia (HP:0003038)1.52651259
150Renal duplication (HP:0000075)1.52597997
151Renal dysplasia (HP:0000110)1.51877619
152Patellar aplasia (HP:0006443)1.50501327
153Tibial bowing (HP:0002982)1.49858051
154Preaxial hand polydactyly (HP:0001177)1.49817688
155Drooling (HP:0002307)1.49776854
156Volvulus (HP:0002580)1.47838135
157Dynein arm defect of respiratory motile cilia (HP:0012255)1.47786934
158Absent/shortened dynein arms (HP:0200106)1.47786934
159Absent frontal sinuses (HP:0002688)1.47240729
160Hyperventilation (HP:0002883)1.46590355
161Vitreoretinal degeneration (HP:0000655)1.46343991
162Oligodactyly (HP:0012165)1.43040415
163Esophageal atresia (HP:0002032)1.42962613

Predicted kinase interactions (KEA)

RankGene SetZ-score
1TNIK3.78641172
2SIK33.75801990
3FRK3.61835493
4PNCK3.53880268
5ERBB33.14980383
6CASK3.07789577
7MAP3K93.05102222
8DDR22.97294764
9LATS12.58210830
10MAP3K22.50514917
11LATS22.47048771
12STK38L2.45090737
13PLK22.40688608
14BCR2.23507540
15PINK12.22521308
16PDGFRA2.18067623
17EPHA42.06422505
18EPHB21.98632844
19MINK11.83494675
20NTRK31.81721312
21FER1.78835991
22KSR11.76298068
23MAPK151.69194485
24SGK21.68102292
25MARK11.60360398
26ZAK1.60130163
27TSSK61.51486288
28STK241.50989674
29EPHA21.43166899
30PRPF4B1.40880611
31WEE11.33793571
32SGK31.31925405
33FGFR21.31752002
34PRKD31.31131550
35SGK2231.27668261
36SGK4941.27668261
37TRIM281.27376087
38MAPK131.19099986
39MAP3K61.15900562
40FGFR11.13069336
41PAK31.12184016
42BMPR1B1.11509003
43PRKCH1.10969086
44DYRK31.10287405
45AKT31.05146728
46CAMK1G1.04067967
47STK31.03602444
48MAP2K11.01688898
49MAP3K31.00670491
50PTK2B0.99539825
51TTN0.98938362
52TAOK20.97616514
53BRD40.97381912
54MAP3K40.96406587
55LIMK10.95704610
56EPHA30.92957345
57CDK80.91900489
58PRKCE0.90777315
59PLK30.87740544
60RPS6KA20.87598470
61CSNK1G20.87349502
62SIK10.86962522
63MET0.86939408
64PTK20.85488793
65BMPR20.83564794
66WNK30.82206285
67ROCK10.81560966
68CDK30.75943023
69CAMKK10.75494592
70MAP2K70.75143224
71CDK180.74538900
72TESK10.74365931
73SIK20.73884697
74TYRO30.73748832
75CSNK1G10.73161081
76PRKCG0.71004426
77PAK60.70568704
78PAK20.66819360
79ARAF0.66113031
80PIK3CA0.64510106
81PDGFRB0.63726157
82TRPM70.63114587
83YES10.62528295
84CDK140.62127017
85NEK90.61482115
86CDC42BPA0.61374068
87ROCK20.60663957
88DYRK1A0.58890392
89NTRK10.58170013
90CDK120.57240120
91ILK0.56765397
92MAP2K40.56313085
93RPS6KC10.54351472
94RPS6KL10.54351472
95PTK60.54293143
96MOS0.54229373
97CAMK1D0.52707851
98CAMK2B0.51905609
99CDK150.50309687
100CAMK2A0.49761353
101NEK60.49533868
102CSNK1E0.48876236
103PKN20.47384775
104PRKCI0.47260370
105CDK50.46619915
106DMPK0.45935703
107CAMK40.45089710
108STK390.44742678
109ADRBK10.44621510
110DAPK20.44169991
111STK380.43430139
112MKNK20.43278211
113PHKG10.43115022
114PHKG20.43115022
115TGFBR10.43051932
116CDK70.42399909
117GRK10.42399435
118DYRK20.41833451
119BRSK20.41555966
120MUSK0.41401122
121RET0.41300613
122MTOR0.40944402
123MAP3K100.40602735
124ERBB20.40238557
125CSNK1A1L0.40016199
126MAPK100.40015567
127MKNK10.39988715
128NEK20.39740591
129MAPK80.39271695
130CDK60.39088257
131TRIB30.38937693
132ICK0.38889755
133SGK10.38861596
134RPS6KA60.38777157
135INSRR0.37571027
136CSNK1G30.37555110
137MYLK0.37392662
138RPS6KB10.37339865
139CDK11A0.35800552
140NTRK20.34909962
141WNK10.34401317
142NLK0.32814405
143FGFR30.31144125
144RIPK10.31007820

Predicted pathways (KEGG)

RankGene SetZ-score
1Axon guidance_Homo sapiens_hsa043602.16092327
2Basal cell carcinoma_Homo sapiens_hsa052172.03539275
3Hippo signaling pathway_Homo sapiens_hsa043901.97913492
4ECM-receptor interaction_Homo sapiens_hsa045121.94867868
5Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054121.89647653
6Adherens junction_Homo sapiens_hsa045201.88658892
7Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005341.80277138
8Vasopressin-regulated water reabsorption_Homo sapiens_hsa049621.75524456
9Hedgehog signaling pathway_Homo sapiens_hsa043401.72998073
10Amphetamine addiction_Homo sapiens_hsa050311.72396393
11TGF-beta signaling pathway_Homo sapiens_hsa043501.67279748
12Dilated cardiomyopathy_Homo sapiens_hsa054141.66255878
13Focal adhesion_Homo sapiens_hsa045101.60436300
14Olfactory transduction_Homo sapiens_hsa047401.60010481
15Dopaminergic synapse_Homo sapiens_hsa047281.58235666
16Circadian entrainment_Homo sapiens_hsa047131.55713461
17Gap junction_Homo sapiens_hsa045401.55485785
18Endometrial cancer_Homo sapiens_hsa052131.53595933
19Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001301.51677583
20Synaptic vesicle cycle_Homo sapiens_hsa047211.49357022
21Cocaine addiction_Homo sapiens_hsa050301.49319754
22Wnt signaling pathway_Homo sapiens_hsa043101.49201089
23Long-term potentiation_Homo sapiens_hsa047201.48147521
24Melanogenesis_Homo sapiens_hsa049161.48126508
25Nicotine addiction_Homo sapiens_hsa050331.47219005
26Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054101.44044170
27Proteoglycans in cancer_Homo sapiens_hsa052051.40900208
28Glioma_Homo sapiens_hsa052141.38704427
29Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045501.38402910
30Taurine and hypotaurine metabolism_Homo sapiens_hsa004301.36802287
31Steroid biosynthesis_Homo sapiens_hsa001001.35697017
32Melanoma_Homo sapiens_hsa052181.29291006
33Thyroid cancer_Homo sapiens_hsa052161.28323058
34Vibrio cholerae infection_Homo sapiens_hsa051101.24751068
35Cholinergic synapse_Homo sapiens_hsa047251.23828674
36Sulfur relay system_Homo sapiens_hsa041221.22443542
37Taste transduction_Homo sapiens_hsa047421.19880553
38Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042611.17077061
39Morphine addiction_Homo sapiens_hsa050321.16249692
40Phototransduction_Homo sapiens_hsa047441.15600986
41Colorectal cancer_Homo sapiens_hsa052101.14546166
42Selenocompound metabolism_Homo sapiens_hsa004501.13333617
43Serotonergic synapse_Homo sapiens_hsa047261.13217035
44Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005321.12788571
45Renin secretion_Homo sapiens_hsa049241.12777420
46Aldosterone synthesis and secretion_Homo sapiens_hsa049251.12457472
47Prostate cancer_Homo sapiens_hsa052151.12085575
48Bacterial invasion of epithelial cells_Homo sapiens_hsa051001.11436016
49Tight junction_Homo sapiens_hsa045301.11162674
50Retrograde endocannabinoid signaling_Homo sapiens_hsa047231.09880545
51GnRH signaling pathway_Homo sapiens_hsa049121.09769365
52Protein digestion and absorption_Homo sapiens_hsa049741.09501436
53Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005331.09097350
54Glutamatergic synapse_Homo sapiens_hsa047241.05953647
55ErbB signaling pathway_Homo sapiens_hsa040121.05679826
56Oxytocin signaling pathway_Homo sapiens_hsa049211.04187193
57Rap1 signaling pathway_Homo sapiens_hsa040151.03367686
58Insulin secretion_Homo sapiens_hsa049111.03165800
59Cardiac muscle contraction_Homo sapiens_hsa042601.02142544
60Amoebiasis_Homo sapiens_hsa051461.01696616
61MicroRNAs in cancer_Homo sapiens_hsa052061.01272015
62Pathogenic Escherichia coli infection_Homo sapiens_hsa051301.00971997
63AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049330.99369866
64Salivary secretion_Homo sapiens_hsa049700.99095400
65Estrogen signaling pathway_Homo sapiens_hsa049150.98658202
66Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.97192537
67Long-term depression_Homo sapiens_hsa047300.96907719
68GABAergic synapse_Homo sapiens_hsa047270.96714784
69Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049600.95809643
70Calcium signaling pathway_Homo sapiens_hsa040200.95612370
71cAMP signaling pathway_Homo sapiens_hsa040240.92866240
72Longevity regulating pathway - mammal_Homo sapiens_hsa042110.92305485
73Thyroid hormone signaling pathway_Homo sapiens_hsa049190.92182063
74PI3K-Akt signaling pathway_Homo sapiens_hsa041510.91762084
75Chronic myeloid leukemia_Homo sapiens_hsa052200.89631156
76Pathways in cancer_Homo sapiens_hsa052000.89391220
77Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049610.89335561
78Gastric acid secretion_Homo sapiens_hsa049710.89151094
79Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.89030567
80Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.88846962
81Collecting duct acid secretion_Homo sapiens_hsa049660.86652289
82cGMP-PKG signaling pathway_Homo sapiens_hsa040220.86521635
83Neurotrophin signaling pathway_Homo sapiens_hsa047220.85058089
84Bladder cancer_Homo sapiens_hsa052190.83937763
85Sulfur metabolism_Homo sapiens_hsa009200.80764130
86Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.80632369
87MAPK signaling pathway_Homo sapiens_hsa040100.78943755
88Non-small cell lung cancer_Homo sapiens_hsa052230.77911324
89Regulation of actin cytoskeleton_Homo sapiens_hsa048100.75587961
90Oocyte meiosis_Homo sapiens_hsa041140.75408328
91AMPK signaling pathway_Homo sapiens_hsa041520.74351304
92Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.71733003
93Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.70354720
94Vascular smooth muscle contraction_Homo sapiens_hsa042700.68801332
95Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047500.68498401
96Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.68345302
97Ras signaling pathway_Homo sapiens_hsa040140.68153955
98Fanconi anemia pathway_Homo sapiens_hsa034600.66716305
99Thyroid hormone synthesis_Homo sapiens_hsa049180.66709877
100Renal cell carcinoma_Homo sapiens_hsa052110.66468793
101FoxO signaling pathway_Homo sapiens_hsa040680.64289626
102Circadian rhythm_Homo sapiens_hsa047100.63602633
103Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.63310884
104Synthesis and degradation of ketone bodies_Homo sapiens_hsa000720.63091419
105Basal transcription factors_Homo sapiens_hsa030220.62342910
106Pancreatic cancer_Homo sapiens_hsa052120.60863971
107Small cell lung cancer_Homo sapiens_hsa052220.59002556
108Phagosome_Homo sapiens_hsa041450.58740760
109Dorso-ventral axis formation_Homo sapiens_hsa043200.57240367
110Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.56811765
111Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.55504659
112Choline metabolism in cancer_Homo sapiens_hsa052310.53289738
113HTLV-I infection_Homo sapiens_hsa051660.52689855
114Cell cycle_Homo sapiens_hsa041100.51708798
115Type II diabetes mellitus_Homo sapiens_hsa049300.51157829
116Prolactin signaling pathway_Homo sapiens_hsa049170.49568717
117Insulin signaling pathway_Homo sapiens_hsa049100.47299250
118Notch signaling pathway_Homo sapiens_hsa043300.42632209
119Fatty acid biosynthesis_Homo sapiens_hsa000610.42069157
120Nucleotide excision repair_Homo sapiens_hsa034200.40336987
121Alcoholism_Homo sapiens_hsa050340.39678409

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