SCGB3A1

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1axoneme assembly (GO:0035082)9.60100735
2left/right pattern formation (GO:0060972)8.98961614
3one-carbon compound transport (GO:0019755)8.36066921
4ethanol oxidation (GO:0006069)8.06592261
5regulation of cilium movement (GO:0003352)7.65973004
6gas transport (GO:0015669)6.96624606
7vitamin transmembrane transport (GO:0035461)6.77627707
8left/right axis specification (GO:0070986)6.69137286
9ethanol metabolic process (GO:0006067)6.63255618
10ventricular system development (GO:0021591)6.39759993
11microtubule bundle formation (GO:0001578)6.13721662
12diterpenoid biosynthetic process (GO:0016102)5.95793164
13L-ascorbic acid metabolic process (GO:0019852)5.93389576
14intraciliary transport (GO:0042073)5.87261360
15response to xenobiotic stimulus (GO:0009410)5.68362385
16positive regulation of ryanodine-sensitive calcium-release channel activity (GO:0060316)5.52366100
17tolerance induction (GO:0002507)5.49634619
18cilium organization (GO:0044782)5.49122077
19negative regulation of immunoglobulin mediated immune response (GO:0002890)5.47041759
20negative regulation of B cell mediated immunity (GO:0002713)5.47041759
21cilium assembly (GO:0042384)5.33225209
22detection of bacterium (GO:0016045)5.26752845
23pyrimidine-containing compound transmembrane transport (GO:0072531)5.19685923
24lung epithelium development (GO:0060428)5.18501319
25regulation of skeletal muscle contraction (GO:0014819)5.02135022
26detection of other organism (GO:0098543)5.01160572
27primary alcohol catabolic process (GO:0034310)4.96372040
28xenobiotic catabolic process (GO:0042178)4.95919547
29establishment of apical/basal cell polarity (GO:0035089)4.95838261
30regulation of interleukin-5 production (GO:0032674)4.94125119
31negative regulation of T cell differentiation in thymus (GO:0033085)4.81204242
32centriole assembly (GO:0098534)4.80511679
33lung lobe morphogenesis (GO:0060463)4.79662443
34negative regulation of ryanodine-sensitive calcium-release channel activity (GO:0060315)4.70805421
35positive regulation of endothelial cell differentiation (GO:0045603)4.65419863
36regulation of toll-like receptor 4 signaling pathway (GO:0034143)4.63280209
37positive regulation of transcription from RNA polymerase II promoter in response to stress (GO:003604.58941580
38protein localization to cilium (GO:0061512)4.56791955
39regulation of germinal center formation (GO:0002634)4.48948154
40regulation of microtubule-based movement (GO:0060632)4.43240123
41sperm capacitation (GO:0048240)4.42013829
42microtubule-based movement (GO:0007018)4.36735180
43glutathione derivative metabolic process (GO:1901685)4.35639846
44glutathione derivative biosynthetic process (GO:1901687)4.35639846
45positive regulation of hormone biosynthetic process (GO:0046886)4.34164065
46regulation of endothelial cell differentiation (GO:0045601)4.30939066
47morphogenesis of an endothelium (GO:0003159)4.30282570
48endothelial tube morphogenesis (GO:0061154)4.30282570
49establishment or maintenance of monopolar cell polarity (GO:0061339)4.26735206
50establishment of monopolar cell polarity (GO:0061162)4.26735206
51epithelial cell differentiation involved in prostate gland development (GO:0060742)4.22211724
52cellular component assembly involved in morphogenesis (GO:0010927)4.22161900
53terpenoid biosynthetic process (GO:0016114)4.13818821
54retinoic acid metabolic process (GO:0042573)4.12520355
55negative regulation of toll-like receptor 4 signaling pathway (GO:0034144)4.07835593
56cellular response to arsenic-containing substance (GO:0071243)4.03279761
57cell projection assembly (GO:0030031)3.93060661
58camera-type eye morphogenesis (GO:0048593)3.89126917
59toxin metabolic process (GO:0009404)3.81751093
60cilium morphogenesis (GO:0060271)3.81066419
61regulation of vasculogenesis (GO:2001212)3.77090111
62epithelial tube branching involved in lung morphogenesis (GO:0060441)3.69417049
63nucleoside diphosphate phosphorylation (GO:0006165)3.68904053
64cytoplasmic microtubule organization (GO:0031122)3.65872845
65establishment of planar polarity (GO:0001736)3.61264038
66establishment of tissue polarity (GO:0007164)3.61264038
67negative regulation of epidermal cell differentiation (GO:0045605)3.61106723
68positive regulation of steroid biosynthetic process (GO:0010893)3.57190053
69cellular response to nitric oxide (GO:0071732)3.55361940
70regulation of humoral immune response mediated by circulating immunoglobulin (GO:0002923)3.53421558
71regulation of transcription from RNA polymerase II promoter in response to oxidative stress (GO:00433.52016373
72negative regulation of inclusion body assembly (GO:0090084)3.51639272
73primary alcohol metabolic process (GO:0034308)3.50085739
74regulation of steroid hormone biosynthetic process (GO:0090030)3.47567122
75respiratory tube development (GO:0030323)3.46944710
76regulation of natural killer cell differentiation (GO:0032823)3.42680803
77hemidesmosome assembly (GO:0031581)3.41932520
78O-glycan processing (GO:0016266)3.34451188
79microtubule depolymerization (GO:0007019)3.32580333
80sodium ion homeostasis (GO:0055078)3.22278462
81microtubule polymerization or depolymerization (GO:0031109)3.15256648
82mesodermal cell differentiation (GO:0048333)3.14572303
83aldehyde catabolic process (GO:0046185)3.14080220
84lymphangiogenesis (GO:0001946)3.13855393
85positive regulation of tolerance induction (GO:0002645)3.12651180
86iron ion import (GO:0097286)3.10660827
87lymph vessel development (GO:0001945)3.10457736
88dichotomous subdivision of an epithelial terminal unit (GO:0060600)3.09708846
89positive regulation of hormone metabolic process (GO:0032352)3.09479568
90epoxygenase P450 pathway (GO:0019373)3.09436827
91regulation of cholesterol biosynthetic process (GO:0045540)3.09061077
92positive regulation of vasculogenesis (GO:2001214)3.08261693
93flavonoid metabolic process (GO:0009812)3.07789080
94blood vessel maturation (GO:0001955)3.05997667
95hydrogen peroxide biosynthetic process (GO:0050665)3.04158094
96positive regulation of smoothened signaling pathway (GO:0045880)3.01786752
97axonemal dynein complex assembly (GO:0070286)21.4740370
98lung vasculature development (GO:0060426)2.99544383
99positive regulation of wound healing (GO:0090303)2.99431973
100blood vessel remodeling (GO:0001974)2.96457900
101cell adhesion mediated by integrin (GO:0033627)2.96109888
102calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules (GO:0016338)2.95552956
103multicellular organismal water homeostasis (GO:0050891)2.93280596
104regulation of microtubule depolymerization (GO:0031114)2.91806254
105embryonic foregut morphogenesis (GO:0048617)2.89030837
106polarized epithelial cell differentiation (GO:0030859)2.88400398
107detection of external biotic stimulus (GO:0098581)2.88166020
108cellular response to follicle-stimulating hormone stimulus (GO:0071372)2.87133034
109drug catabolic process (GO:0042737)2.86197573
110negative regulation of interferon-gamma production (GO:0032689)2.85709158
111apical protein localization (GO:0045176)2.85694677
112negative regulation of lipopolysaccharide-mediated signaling pathway (GO:0031665)2.85390423
113cellular response to reactive nitrogen species (GO:1902170)2.83719595
114lateral sprouting from an epithelium (GO:0060601)2.83538429
115apoptotic cell clearance (GO:0043277)2.83466081
116positive regulation of mitochondrial calcium ion concentration (GO:0051561)2.82773325
117midgut development (GO:0007494)2.82728048
118retinol metabolic process (GO:0042572)2.82480592
119phospholipase C-activating dopamine receptor signaling pathway (GO:0060158)2.82240353
120carnitine metabolic process (GO:0009437)2.82006292
121regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator 2.79537388
122negative regulation of epidermis development (GO:0045683)2.79485600
123retina vasculature morphogenesis in camera-type eye (GO:0061299)2.78970831
124lung alveolus development (GO:0048286)2.78599605
125excretion (GO:0007588)2.78472424
126hydrogen peroxide catabolic process (GO:0042744)2.77289974
127negative regulation of humoral immune response (GO:0002921)2.76811257
128glomerular epithelial cell development (GO:0072310)2.76707851
129protein localization to endosome (GO:0036010)2.74225912
130hypotonic response (GO:0006971)2.73203828
131NADP metabolic process (GO:0006739)2.73148240
132regulation of peroxisome proliferator activated receptor signaling pathway (GO:0035358)2.71619590
133progesterone metabolic process (GO:0042448)2.71440073
134macrophage chemotaxis (GO:0048246)2.70163197
135reactive oxygen species biosynthetic process (GO:1903409)2.70107013
136positive regulation of osteoblast proliferation (GO:0033690)2.69616336
137positive regulation of vesicle fusion (GO:0031340)2.69260606
138response to nitric oxide (GO:0071731)2.69172855
139oligosaccharide biosynthetic process (GO:0009312)2.66797895
140regulation of response to osmotic stress (GO:0047484)2.65986723
141lateral ventricle development (GO:0021670)2.65438134
142polyol transport (GO:0015791)2.64201460
143hormone catabolic process (GO:0042447)2.61352588
144regulation of apoptotic cell clearance (GO:2000425)2.60646340
145cellular aldehyde metabolic process (GO:0006081)2.60544578
146regulation of tolerance induction (GO:0002643)2.60428270
147peptide catabolic process (GO:0043171)2.60076044
148vascular endothelial growth factor signaling pathway (GO:0038084)2.59594839
149respiratory gaseous exchange (GO:0007585)2.58623760
150determination of left/right symmetry (GO:0007368)2.57954923
151endocardial cushion development (GO:0003197)2.57639174
152regulation of hormone biosynthetic process (GO:0046885)2.56570429
153regulation of autophagic vacuole assembly (GO:2000785)2.55821521
154positive regulation of calcium ion transmembrane transporter activity (GO:1901021)2.55409495
155epithelial cell-cell adhesion (GO:0090136)2.55076378
156negative regulation of response to reactive oxygen species (GO:1901032)2.54894183
157microtubule-based process (GO:0007017)2.53533965
158negative regulation of endoplasmic reticulum calcium ion concentration (GO:0032471)2.52836614
159NADPH regeneration (GO:0006740)2.51840555
160regulation of interleukin-13 production (GO:0032656)2.51415014
161phosphatidylcholine biosynthetic process (GO:0006656)2.50574074
162pentose-phosphate shunt (GO:0006098)2.49999546
163exogenous drug catabolic process (GO:0042738)2.49600214
164water homeostasis (GO:0030104)2.49568329
165establishment or maintenance of apical/basal cell polarity (GO:0035088)2.49522881
166establishment or maintenance of bipolar cell polarity (GO:0061245)2.49522881
167sperm motility (GO:0030317)2.49235359
168determination of bilateral symmetry (GO:0009855)2.47716027
169cilium or flagellum-dependent cell motility (GO:0001539)17.5724626
170cilium movement (GO:0003341)14.9997546
171motile cilium assembly (GO:0044458)14.2565849
172epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287)13.8769711
173surfactant homeostasis (GO:0043129)13.0421296
174epithelial cilium movement (GO:0003351)12.8140904
175chemical homeostasis within a tissue (GO:0048875)10.3812238

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat5.94076154
2TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse4.86899705
3TRIM28_21343339_ChIP-Seq_HEK293_Human4.68040934
4RARG_19884340_ChIP-ChIP_MEFs_Mouse3.94765110
5PPARG_19300518_ChIP-PET_3T3-L1_Mouse3.87224392
6TP63_17297297_ChIP-ChIP_HaCaT_Human3.85046914
7GATA1_22025678_ChIP-Seq_K562_Human3.45850344
8DROSHA_22980978_ChIP-Seq_HELA_Human3.17739934
9TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse3.04644217
10CLOCK_20551151_ChIP-Seq_293T_Human2.73961902
11STAT6_21828071_ChIP-Seq_BEAS2B_Human2.52039764
12ESR2_21235772_ChIP-Seq_MCF-7_Human2.51540934
13ESR1_21235772_ChIP-Seq_MCF-7_Human2.49724622
14PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse2.37161053
15SMAD4_19686287_ChIP-ChIP_HaCaT_Human2.30368319
16SOX2_27498859_Chip-Seq_STOMACH_Mouse2.26506371
17SOX2_20726797_ChIP-Seq_SW620_Human2.19711045
18ESR1_15608294_ChIP-ChIP_MCF-7_Human2.06694220
19BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse2.05953746
20ZNF263_19887448_ChIP-Seq_K562_Human1.98635685
21FOXA1_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human1.93713496
22NANOG_18700969_ChIP-ChIP_MESCs_Mouse1.91099649
23CHD7_19251738_ChIP-ChIP_MESCs_Mouse1.89968046
24GATA2_21666600_ChIP-Seq_HMVEC_Human1.89737937
25STAT5_23275557_ChIP-Seq_MAMMARY-EPITHELIUM_Mouse1.87410642
26* ESR1_20079471_ChIP-ChIP_T-47D_Human1.85796101
27* SMC4_20622854_ChIP-Seq_HELA_Human1.81484914
28TFAP2C_20629094_ChIP-Seq_MCF-7_Human1.81358702
29PPAR_26484153_Chip-Seq_NCI-H1993_Human1.78414191
30STAT1_20625510_ChIP-Seq_HELA_Human1.78325261
31ZNF217_24962896_ChIP-Seq_MCF-7_Human1.77541796
32KLF6_26769127_Chip-Seq_PDAC-Cell_line_Human1.66239211
33RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human1.61401883
34GATA4_25053715_ChIP-Seq_YYC3_Human1.59936161
35RACK7_27058665_Chip-Seq_MCF-7_Human1.59924322
36ESR1_17901129_ChIP-ChIP_LIVER_Mouse1.58692801
37FOXO3_23340844_ChIP-Seq_DLD1_Human1.57396423
38CDX2_20551321_ChIP-Seq_CACO-2_Human1.56990625
39SMAD3_18955504_ChIP-ChIP_HaCaT_Human1.55255610
40SMAD2_18955504_ChIP-ChIP_HaCaT_Human1.55255610
41TP63_22573176_ChIP-Seq_HFKS_Human1.54238530
42* PBX_27287812_Chip-Seq_EMBYONIC-LIMB_Mouse1.52591185
43NFE2L2_20460467_ChIP-Seq_MEFs_Mouse1.49989193
44NRF2_20460467_ChIP-Seq_MEFs_Mouse1.49989193
45LXR_22158963_ChIP-Seq_LIVER_Mouse1.49516638
46BACH1_22875853_ChIP-PCR_HELA_AND_SCP4_Human1.49450060
47SMARCA4_20176728_ChIP-ChIP_TSCs_Mouse1.48397506
48RAD21_21589869_ChIP-Seq_MESCs_Mouse1.48386467
49CEBPB_23403033_ChIP-Seq_LIVER_Mouse1.46206546
50HIF1A_21447827_ChIP-Seq_MCF-7_Human1.42572596
51AHR_22903824_ChIP-Seq_MCF-7_Human1.41825399
52PPARD_23176727_ChIP-Seq_KERATINOCYTES_Mouse1.41593968
53FOXP3_17237761_ChIP-ChIP_TREG_Mouse1.39788724
54ETV1_20927104_ChIP-Seq_GIST48_Human1.39619437
55KLF4_26769127_Chip-Seq_PDAC-Cell_line_Human1.38847920
56RXR_22158963_ChIP-Seq_LIVER_Mouse1.38206334
57CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human1.38037954
58TDRD3_21172665_ChIP-Seq_MCF-7_Human1.37742617
59CTNNB1_20460455_ChIP-Seq_HCT116_Human1.35955959
60ELF1_20517297_ChIP-Seq_JURKAT_Human1.35947141
61SMAD2/3_21741376_ChIP-Seq_ESCs_Human1.35732728
62SOX9_24532713_ChIP-Seq_HFSC_Mouse1.33689527
63PCGF4_22325352_ChIP-Seq_293T-Rex_Human1.32169816
64TCF4_18268006_ChIP-ChIP_LS174T_Human1.31626216
65RUNX1_27514584_Chip-Seq_MCF-7_Human1.29536205
66ERA_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human1.29067632
67Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse1.28975255
68NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse1.28467469
69ELF3_26769127_Chip-Seq_PDAC-Cell_line_Human1.27959663
70* PIAS1_25552417_ChIP-Seq_VCAP_Human1.27181440
71CEBPB_21427703_ChIP-Seq_3T3-L1_Mouse1.26763649
72CDX2_21074721_ChIP-Seq_CACO-2_Mouse1.26415182
73PHF8_20622853_ChIP-Seq_HELA_Human1.26391530
74CJUN_26792858_Chip-Seq_BT549_Human1.25550006
75FOXM1_26456572_ChIP-Seq_MCF-7_Human1.25368253
76FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse1.24967675
77* SALL4_18804426_ChIP-ChIP_XEN_Mouse1.24634902
78HNFA_21074721_ChIP-Seq_CACO-2_Human1.24159698
79EP300_21415370_ChIP-Seq_HL-1_Mouse1.21828399
80KLF5_25053715_ChIP-Seq_YYC3_Human1.20980987
81CTCF_27219007_Chip-Seq_Bcells_Human1.20412864
82CREB1_26743006_Chip-Seq_LNCaP-abl_Human1.20291506
83TBX20_22328084_ChIP-Seq_HEART_Mouse1.18490510
84TBX20_22080862_ChIP-Seq_HEART_Mouse1.18490510
85RBPJ_21746931_ChIP-Seq_IB4_Human1.18022133
86* CREB1_26743006_Chip-Seq_LNCaP_Human1.17002802
87SMRT_27268052_Chip-Seq_Bcells_Human1.16706161
88NR3C1_21868756_ChIP-Seq_MCF10A_Human1.15787745
89PPARA_22158963_ChIP-Seq_LIVER_Mouse1.14954516
90ARNT_22903824_ChIP-Seq_MCF-7_Human1.14584582
91* AR_21915096_ChIP-Seq_LNCaP-1F5_Human1.13823061
92P68_20966046_ChIP-Seq_HELA_Human1.11632356
93YY1_22570637_ChIP-Seq_MALME-3M_Human1.11544486
94GATA6_21074721_ChIP-Seq_CACO-2_Mouse1.11520941
95CTCF_20526341_ChIP-Seq_ESCs_Human1.11279874
96ESR1_22446102_ChIP-Seq_UTERUS_Mouse1.10967331
97TP53_18474530_ChIP-ChIP_U2OS_Human1.10881004
98CBX2_22325352_ChIP-Seq_293T-Rex_Human1.10265983
99VDR_22108803_ChIP-Seq_LS180_Human1.10103733
100FOXA1_26743006_Chip-Seq_LNCaP-abl_Human1.10098740
101GATA6_21074721_ChIP-Seq_CACO-2_Human1.09728486
102FOXA1_26769127_Chip-Seq_PDAC-Cell_line_Human1.09639907
103STAT6_20620947_ChIP-Seq_CD4_POS_T_Human1.09374757
104GATA1_19941826_ChIP-Seq_K562_Human1.08613970
105IKZF1_21737484_ChIP-ChIP_HCT116_Human1.08257959
106TCF21_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human1.07655023
107GATA6_25053715_ChIP-Seq_YYC3_Human1.06882299
108ELK3_25401928_ChIP-Seq_HUVEC_Human1.06863748
109P63_26484246_Chip-Seq_KERATINOCYTES_Human1.04317527
110CDX2_19796622_ChIP-Seq_MESCs_Mouse1.03543658
111THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse1.03395418
112SMAD3_21741376_ChIP-Seq_HESCs_Human1.03369925
113TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human1.03344855
114PHF8_20622854_ChIP-Seq_HELA_Human1.01749217
115GATA3_24758297_ChIP-Seq_MCF-7_Human0.99731562
116NFYA_21822215_ChIP-Seq_K562_Human0.99154870
117NR1I2_20693526_ChIP-Seq_LIVER_Mouse0.98408796
118JUND_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human0.97526840
119* FOXA1_21915096_ChIP-Seq_LNCaP-1F5_Human0.96257321
120BP1_19119308_ChIP-ChIP_Hs578T_Human0.96180342
121CEBPB_22108803_ChIP-Seq_LS180_Human0.93105709
122NACC1_18358816_ChIP-ChIP_MESCs_Mouse0.91963454
123RUNX2_24764292_ChIP-Seq_MC3T3_Mouse0.91657025
124* EP300_20729851_ChIP-Seq_FORBRAIN_MIDBRAIN_LIMB_HEART_Mouse0.91513507
125P300_27268052_Chip-Seq_Bcells_Human0.91047321
126FOXA2_19822575_ChIP-Seq_HepG2_Human0.90406673
127NFYB_21822215_ChIP-Seq_K562_Human0.89421966
128P300_27058665_Chip-Seq_ZR-75-30cells_Human0.89197339
129CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons0.88948682
130TAL1_22897851_ChIP-Seq_JUKARTE6-1_Human0.88826859
131HSF1_23293686_ChIP-Seq_STHDH_STRIATAL_Mouse0.88493488
132GATA2_19941826_ChIP-Seq_K562_Human0.88045710
133FOXO1_23066095_ChIP-Seq_LIVER_Mouse0.87744321
134FLI1_21867929_ChIP-Seq_CD8_Mouse0.87391233
135SA1_27219007_Chip-Seq_ERYTHROID_Human0.86669974
136TAF7L_23326641_ChIP-Seq_C3H10T1-2_Mouse0.86338825
137LXR_22292898_ChIP-Seq_THP-1_Human0.85535982
138CEBPA_23403033_ChIP-Seq_LIVER_Mouse0.85098459
139SIN3B_21632747_ChIP-Seq_MESCs_Mouse0.84997887
140SMAD3_22036565_ChIP-Seq_ESCs_Mouse0.84871162
141* TP63_23658742_ChIP-Seq_EP156T_Human0.82416199
142SUZ12_18692474_ChIP-Seq_MEFs_Mouse0.82068111
143NFE2L2_22581777_ChIP-Seq_LYMPHOBLASTOID_Human0.81693913
144FOXA1_25552417_ChIP-Seq_VCAP_Human0.80223139
145SPI1_23127762_ChIP-Seq_K562_Human0.79856537
146NFIB_24661679_ChIP-Seq_LUNG_Mouse0.77903416
147CTNNB1_24651522_ChIP-Seq_LGR5+_INTESTINAL_STEM_Human0.77015064
148ETS2_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse0.75672514
149JUN_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human0.75169505
150BCAT_22108803_ChIP-Seq_LS180_Human0.74086054
151NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human0.73458072

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0004782_abnormal_surfactant_physiolog6.29557801
2MP0002653_abnormal_ependyma_morphology5.76747149
3MP0001958_emphysema4.82345244
4MP0008875_abnormal_xenobiotic_pharmacok4.68440078
5MP0005083_abnormal_biliary_tract3.99284316
6MP0004043_abnormal_pH_regulation3.92542653
7MP0010234_abnormal_vibrissa_follicle3.90035524
8MP0002139_abnormal_hepatobiliary_system3.67329844
9MP0001984_abnormal_olfaction3.63655772
10MP0004133_heterotaxia3.17817089
11MP0008789_abnormal_olfactory_epithelium3.09778615
12MP0002138_abnormal_hepatobiliary_system3.07721792
13MP0010368_abnormal_lymphatic_system2.96392421
14MP0005167_abnormal_blood-brain_barrier2.80995026
15MP0003566_abnormal_cell_adhesion2.66029046
16MP0001879_abnormal_lymphatic_vessel2.59462173
17MP0002132_abnormal_respiratory_system2.58737282
18MP0005248_abnormal_Harderian_gland2.58558133
19MP0003806_abnormal_nucleotide_metabolis2.35774279
20MP0008995_early_reproductive_senescence2.28465639
21MP0004272_abnormal_basement_membrane2.16315403
22MP0000537_abnormal_urethra_morphology2.15053811
23MP0003191_abnormal_cellular_cholesterol2.14999331
24MP0002133_abnormal_respiratory_system2.13627382
25MP0005388_respiratory_system_phenotype2.13627382
26MP0003656_abnormal_erythrocyte_physiolo2.08287891
27MP0005499_abnormal_olfactory_system1.98858807
28MP0005394_taste/olfaction_phenotype1.98858807
29MP0006054_spinal_hemorrhage1.88647975
30MP0001765_abnormal_ion_homeostasis1.87793669
31MP0005377_hearing/vestibular/ear_phenot1.85807606
32MP0003878_abnormal_ear_physiology1.85807606
33MP0002295_abnormal_pulmonary_circulatio1.84228223
34MP0003186_abnormal_redox_activity1.82763296
35MP0003724_increased_susceptibility_to1.78080868
36MP0008004_abnormal_stomach_pH1.75074665
37MP0002277_abnormal_respiratory_mucosa1.72405994
38MP0002909_abnormal_adrenal_gland1.69842338
39MP0000678_abnormal_parathyroid_gland1.67683805
40MP0000465_gastrointestinal_hemorrhage1.60410728
41MP0010678_abnormal_skin_adnexa1.48413999
42MP0005164_abnormal_response_to1.46492120
43MP0002160_abnormal_reproductive_system1.44936633
44MP0001177_atelectasis1.40410918
45MP0005365_abnormal_bile_salt1.38064953
46MP0004264_abnormal_extraembryonic_tissu1.34712589
47MP0005085_abnormal_gallbladder_physiolo1.29173941
48MP0005636_abnormal_mineral_homeostasis1.29071669
49MP0003705_abnormal_hypodermis_morpholog1.24051341
50MP0000343_altered_response_to1.21011309
51MP0005395_other_phenotype1.19618889
52MP0003303_peritoneal_inflammation1.18812158
53MP0001849_ear_inflammation1.18736473
54MP0010352_gastrointestinal_tract_polyps1.16649041
55MP0002249_abnormal_larynx_morphology1.15272476
56MP0005408_hypopigmentation1.12131234
57MP0003453_abnormal_keratinocyte_physiol1.11775517
58MP0003075_altered_response_to1.10391653
59MP0009785_altered_susceptibility_to1.06889272
60MP0002796_impaired_skin_barrier1.05724407
61MP0003828_pulmonary_edema1.05673393
62MP0000681_abnormal_thyroid_gland1.05439785
63MP0002098_abnormal_vibrissa_morphology1.03993456
64MP0002234_abnormal_pharynx_morphology1.02150868
65MP0009764_decreased_sensitivity_to1.01364156
66MP0000249_abnormal_blood_vessel1.00869083
67MP0003690_abnormal_glial_cell0.99192184
68MP0006138_congestive_heart_failure0.98995444
69MP0005058_abnormal_lysosome_morphology0.97246105
70MP0010329_abnormal_lipoprotein_level0.93778999
71MP0001175_abnormal_lung_morphology0.93589144
72MP0004883_abnormal_blood_vessel0.93462149
73MP0005166_decreased_susceptibility_to0.93458827
74MP0003300_gastrointestinal_ulcer0.91302052
75MP0000467_abnormal_esophagus_morphology0.90568545
76MP0005623_abnormal_meninges_morphology0.90266756
77MP0005275_abnormal_skin_tensile0.89972862
78MP0002233_abnormal_nose_morphology0.88963199
79MP0010030_abnormal_orbit_morphology0.86667350
80MP0000767_abnormal_smooth_muscle0.85622061
81MP0002876_abnormal_thyroid_physiology0.84773052
82MP0003279_aneurysm0.83817216
83MP0000383_abnormal_hair_follicle0.79374220
84MP0001851_eye_inflammation0.78301975
85MP0000858_altered_metastatic_potential0.76039852
86MP0001346_abnormal_lacrimal_gland0.75754937
87MP0005023_abnormal_wound_healing0.75234919
88MP0000762_abnormal_tongue_morphology0.74729476
89MP0003091_abnormal_cell_migration0.73817457
90MP0003950_abnormal_plasma_membrane0.72773238
91MP0002734_abnormal_mechanical_nocicepti0.72295996
92MP0001943_abnormal_respiration0.71939483
93MP0002638_abnormal_pupillary_reflex0.71195789
94MP0002282_abnormal_trachea_morphology0.70968014
95MP0009643_abnormal_urine_homeostasis0.69835584
96MP0009384_cardiac_valve_regurgitation0.69704407
97MP0002128_abnormal_blood_circulation0.69163216
98MP0005165_increased_susceptibility_to0.68655033
99MP0002118_abnormal_lipid_homeostasis0.68526218
100MP0003115_abnormal_respiratory_system0.68345614
101MP0005397_hematopoietic_system_phenotyp0.67357127
102MP0001545_abnormal_hematopoietic_system0.67357127
103MP0001544_abnormal_cardiovascular_syste0.65455021
104MP0005385_cardiovascular_system_phenoty0.65455021
105MP0002254_reproductive_system_inflammat0.65314049
106MP0001485_abnormal_pinna_reflex0.65189672
107MP0005220_abnormal_exocrine_pancreas0.65009465
108MP0009765_abnormal_xenobiotic_induced0.64992963
109MP0004084_abnormal_cardiac_muscle0.64969171
110MP0001666_abnormal_nutrient_absorption0.64634198
111MP0002925_abnormal_cardiovascular_devel0.64187184
112MP0005025_abnormal_response_to0.64179551
113MP0005319_abnormal_enzyme/_coenzyme0.63990196
114MP0001790_abnormal_immune_system0.63113496
115MP0005387_immune_system_phenotype0.63113496
116MP0003448_altered_tumor_morphology0.62529924
117MP0002405_respiratory_system_inflammati0.61926185
118MP0004484_altered_response_of0.61735454
119MP0005595_abnormal_vascular_smooth0.61690810
120MP0009763_increased_sensitivity_to0.61457004
121MP0009780_abnormal_chondrocyte_physiolo0.61247965
122MP0005409_darkened_coat_color0.60884332
123MP0002136_abnormal_kidney_physiology0.60711786
124MP0003866_abnormal_defecation0.60285083
125MP0004130_abnormal_muscle_cell0.60217141
126MP0001664_abnormal_digestion0.59567582
127MP0006082_CNS_inflammation0.59528377
128MP0010155_abnormal_intestine_physiology0.59253915
129MP0004019_abnormal_vitamin_homeostasis0.58707252
130MP0002168_other_aberrant_phenotype0.58550432
131MP0005389_reproductive_system_phenotype0.58095719
132MP0002735_abnormal_chemical_nociception0.57613383
133MP0004185_abnormal_adipocyte_glucose0.57156390
134MP0000566_synostosis0.54447672
135MP0009379_abnormal_foot_pigmentation0.54324365
136MP0005503_abnormal_tendon_morphology0.53337965
137MP0001270_distended_abdomen0.52316563
138MP0001929_abnormal_gametogenesis0.49421832
139MP0001502_abnormal_circadian_rhythm0.48719084
140MP0005310_abnormal_salivary_gland0.47926494
141MP0002896_abnormal_bone_mineralization0.47376233
142MP0009703_decreased_birth_body0.46504572
143MP0003698_abnormal_male_reproductive0.45593925
144MP0001663_abnormal_digestive_system0.44280272
145MP0002135_abnormal_kidney_morphology0.40519679
146MP0001944_abnormal_pancreas_morphology0.40140111
147MP0000026_abnormal_inner_ear0.37867300
148MP0001324_abnormal_eye_pigmentation0.37676468
149MP0002116_abnormal_craniofacial_bone0.37506413
150MP0008873_increased_physiological_sensi0.36453480

Predicted human phenotypes

RankGene SetZ-score
1Interstitial pulmonary disease (HP:0006530)8.65529580
2Chronic bronchitis (HP:0004469)7.32071620
3Hyperactive renin-angiotensin system (HP:0000841)6.98157608
4Polycythemia (HP:0001901)6.26409360
5Renal salt wasting (HP:0000127)5.72617294
6Tubulointerstitial fibrosis (HP:0005576)5.41417052
7Abnormality of the nasal mucosa (HP:0000433)5.19745641
8Gout (HP:0001997)5.09836227
9Hematochezia (HP:0002573)4.78465066
10Bronchomalacia (HP:0002780)4.69289342
11Ulnar bowing (HP:0003031)4.65472026
12Recurrent sinusitis (HP:0011108)4.47769515
13Infertility (HP:0000789)4.21345679
14Hyperkalemia (HP:0002153)4.11526691
15Synostosis involving the elbow (HP:0003938)4.04942768
16Humeroradial synostosis (HP:0003041)4.04942768
17Recurrent otitis media (HP:0000403)3.98736646
18Male infertility (HP:0003251)3.97335952
19Tubulointerstitial nephritis (HP:0001970)3.90165691
20Onycholysis (HP:0001806)3.89037168
21Bronchitis (HP:0012387)3.65714474
22Tachypnea (HP:0002789)3.50484689
23Spontaneous hematomas (HP:0007420)3.49278758
24Occipital encephalocele (HP:0002085)3.41983536
25Nasal polyposis (HP:0100582)3.26276424
26Hyperaldosteronism (HP:0000859)3.25696056
27Visceral angiomatosis (HP:0100761)3.24430683
28Pancreatic fibrosis (HP:0100732)3.16576509
29Tubulointerstitial abnormality (HP:0001969)3.15150680
30Hypotension (HP:0002615)3.13355650
31True hermaphroditism (HP:0010459)3.10662942
32Atelectasis (HP:0100750)3.10401747
33Vaginal fistula (HP:0004320)3.03735004
34Bowing of the arm (HP:0006488)3.02124962
35Bowed forearm bones (HP:0003956)3.02124962
36Right ventricular cardiomyopathy (HP:0011663)3.01051109
37Tubular atrophy (HP:0000092)2.98013170
38Hemangiomatosis (HP:0007461)2.95848212
39Respiratory distress (HP:0002098)2.95615968
40Bronchiectasis (HP:0002110)2.93722332
41Abnormality of chloride homeostasis (HP:0011422)2.92390489
42Esophageal varix (HP:0002040)2.88781095
43Abnormality of renin-angiotensin system (HP:0000847)2.84065157
44Scanning speech (HP:0002168)2.81007505
45Pustule (HP:0200039)2.71963240
46Abnormal hemoglobin (HP:0011902)2.70880066
47Cystic liver disease (HP:0006706)2.65443856
48Fragile nails (HP:0001808)2.61600610
49Cerebral hemorrhage (HP:0001342)2.61354186
50Neurofibrillary tangles (HP:0002185)2.56726668
51Labial hypoplasia (HP:0000066)2.52608993
52Deep venous thrombosis (HP:0002625)2.51774934
53Molar tooth sign on MRI (HP:0002419)2.50072826
54Abnormality of midbrain morphology (HP:0002418)2.50072826
55Pancreatic cysts (HP:0001737)2.49859611
56Subacute progressive viral hepatitis (HP:0006572)2.49465683
57Cerebral aneurysm (HP:0004944)2.49386934
58Milia (HP:0001056)2.44848386
59Glomerulosclerosis (HP:0000096)2.44769431
60Nephronophthisis (HP:0000090)2.41160094
61Arterial tortuosity (HP:0005116)2.35418449
62Vascular calcification (HP:0004934)2.34336592
63Increased purine levels (HP:0004368)2.33048872
64Hyperuricemia (HP:0002149)2.33048872
65Conjunctival telangiectasia (HP:0000524)2.32180818
66Chronic otitis media (HP:0000389)2.28975142
67Hypoplastic female external genitalia (HP:0012815)2.28032464
68Abnormality of the vasculature of the conjunctiva (HP:0008054)2.27597483
69Vascular tortuosity (HP:0004948)2.27249122
70Postaxial foot polydactyly (HP:0001830)2.25193950
71Annular pancreas (HP:0001734)2.24059448
72Cerebral inclusion bodies (HP:0100314)2.20493220
73Bifid scrotum (HP:0000048)2.19180984
74Hyponatremia (HP:0002902)2.18439353
75Decreased circulating renin level (HP:0003351)2.17644606
76Respiratory insufficiency due to defective ciliary clearance (HP:0200073)2.17496172
77Cardiovascular calcification (HP:0011915)2.17276529
78Atrophic scars (HP:0001075)2.16080824
79Single umbilical artery (HP:0001195)2.14933716
80Abnormality of the fetal cardiovascular system (HP:0010948)2.14933716
81Abnormal umbilical cord blood vessels (HP:0011403)2.14933716
82Buphthalmos (HP:0000557)2.13270682
83Chronic hepatic failure (HP:0100626)2.12327923
84Rhinitis (HP:0012384)2.02781123
85Abnormal respiratory motile cilium physiology (HP:0012261)2.01811070
86Alopecia of scalp (HP:0002293)2.01734672
87Bell-shaped thorax (HP:0001591)2.00982250
88Choanal stenosis (HP:0000452)2.00040045
89Abnormal respiratory motile cilium morphology (HP:0005938)11.3498503
90Dynein arm defect of respiratory motile cilia (HP:0012255)10.8810423
91Absent/shortened dynein arms (HP:0200106)10.8810423
92Recurrent bronchitis (HP:0002837)1.97905494
93Adrenal overactivity (HP:0002717)1.97468000
94Abnormal blistering of the skin (HP:0008066)1.96213048
95Absent frontal sinuses (HP:0002688)1.95993653
96Cavernous hemangioma (HP:0001048)1.95961245
97Osteolytic defects of the hand bones (HP:0009699)1.95464866
98Osteolytic defects of the phalanges of the hand (HP:0009771)1.95464866
99Rectal prolapse (HP:0002035)1.92952657
100Growth hormone excess (HP:0000845)1.92422061
101Abnormality of the renal medulla (HP:0100957)1.90557630
102Long toe (HP:0010511)1.90434446
103Eczematoid dermatitis (HP:0000976)1.88734404
104Abnormal ciliary motility (HP:0012262)1.88306920
105Hydroureter (HP:0000072)1.88148859
106Chronic sinusitis (HP:0011109)1.87634874
107Abnormality of purine metabolism (HP:0004352)1.87453431
108Abnormality of sodium homeostasis (HP:0010931)1.87339888
109Congenital hepatic fibrosis (HP:0002612)1.85778062
110Abnormalities of placenta or umbilical cord (HP:0001194)1.80935841
111Anencephaly (HP:0002323)1.80481583
112Oral leukoplakia (HP:0002745)1.80193715
113Spastic diplegia (HP:0001264)1.78489492
114Arnold-Chiari malformation (HP:0002308)1.78236890
115Hypokalemic alkalosis (HP:0001949)1.76787602
116Curly hair (HP:0002212)1.76435943
117Male pseudohermaphroditism (HP:0000037)1.76366649
118Aplasia/Hypoplasia of the tongue (HP:0010295)1.76169053
119Potter facies (HP:0002009)1.76069623
120Facial shape deformation (HP:0011334)1.76069623
121Aortic aneurysm (HP:0004942)1.72625066
122Femoral bowing (HP:0002980)1.72159624
123Plantar hyperkeratosis (HP:0007556)1.70149545
124Asplenia (HP:0001746)1.69313320
125Pulmonary hypertension (HP:0002092)1.68639915
126Aplasia/Hypoplasia of the spleen (HP:0010451)1.67240244
127Abnormal cartilage morphology (HP:0002763)1.66399147
128Abnormal respiratory epithelium morphology (HP:0012253)1.65888463
129Nephropathy (HP:0000112)1.63121345
130Medial flaring of the eyebrow (HP:0010747)1.58829979
131Furrowed tongue (HP:0000221)1.56805238
132Aplasia/Hypoplasia of the frontal sinuses (HP:0009119)1.53875708
133Oculomotor apraxia (HP:0000657)1.52434966
134Congenital primary aphakia (HP:0007707)1.50976993
135Gait imbalance (HP:0002141)1.47206213
136Sclerocornea (HP:0000647)1.42953188
137Postaxial hand polydactyly (HP:0001162)1.38215138
138Abnormality of the distal phalanges of the toes (HP:0010182)1.33965065
139Glucose intolerance (HP:0000833)1.31414952
140Abnormality of monocarboxylic acid metabolism (HP:0010996)1.29895777
141Nephrogenic diabetes insipidus (HP:0009806)1.29436330
142Hand muscle atrophy (HP:0009130)1.25062230
143Short thorax (HP:0010306)1.24565250
144Aplasia/Hypoplasia involving the sinuses (HP:0009120)1.23849378
145Abnormality of permanent molar morphology (HP:0011071)1.22691741
146Abnormality of the dental root (HP:0006486)1.22691741
147Taurodontia (HP:0000679)1.22691741
148Abnormality of the frontal sinuses (HP:0002687)1.22196163
149Median cleft lip (HP:0000161)1.20248425
150Cone-rod dystrophy (HP:0000548)1.19393237
151Obstructive sleep apnea (HP:0002870)1.18903508
152Lip pit (HP:0100267)1.17692813
153Short nail (HP:0001799)1.14919671
154Abnormality of molar morphology (HP:0011070)1.12607275
155Abnormality of molar (HP:0011077)1.12607275
156Absent rod-and cone-mediated responses on ERG (HP:0007688)1.12370097
157Preaxial hand polydactyly (HP:0001177)1.10782882
158Stage 5 chronic kidney disease (HP:0003774)1.10390495
159Popliteal pterygium (HP:0009756)1.10039249
160Abnormality of the dental pulp (HP:0006479)1.08946319
161Fetal akinesia sequence (HP:0001989)1.08506985
162Flat acetabular roof (HP:0003180)1.05505747
163Short femoral neck (HP:0100864)1.05303507
164Decreased central vision (HP:0007663)1.05188038
165Muscle fiber splitting (HP:0003555)1.04332102
166Cone-shaped epiphyses of the phalanges of the hand (HP:0010230)1.02015616
167Spinal muscular atrophy (HP:0007269)0.99921848
168Aplasia of the musculature (HP:0100854)0.99765682
169Poor coordination (HP:0002370)0.99090901
170Vaginal atresia (HP:0000148)0.98073311
171Spinal cord compression (HP:0002176)0.97187289

Predicted kinase interactions (KEA)

RankGene SetZ-score
1TIE14.75816515
2TGFBR23.82678298
3EPHA23.33568313
4MST43.06190902
5LRRK22.83693920
6TRIB32.63825858
7MAPKAPK32.56603294
8EPHB22.51032373
9FER2.42244473
10MAP3K22.37537615
11ZAP702.35005035
12SMG12.33777664
13ERBB32.32502593
14PAK42.32155592
15NME12.30536690
16EPHB12.28369818
17MST1R2.25894197
18DAPK22.12575916
19TRPM72.07865309
20EEF2K2.04093508
21FGFR21.90433365
22PTK61.87511435
23RIPK11.85364987
24TTK1.79766563
25STK101.68058322
26GRK11.58360209
27PTK21.55083044
28KSR21.50787237
29KDR1.48708682
30MAP3K31.46404359
31PDGFRB1.44650518
32STK241.44277005
33ERN11.37237586
34FRK1.34990097
35LMTK21.31052634
36MAP3K121.27042170
37ILK1.24079729
38MET1.23404646
39RIPK41.21183008
40PKN21.21134638
41MYLK1.20085023
42FGFR41.16422661
43NEK61.13900821
44MATK1.10689141
45MAP3K91.08910076
46CSK1.07719221
47TGFBR11.07504082
48PRKD11.03888314
49MARK21.02916733
50TYK21.00194725
51PDPK10.99421702
52MAP2K30.96892884
53FGFR30.96063815
54EPHA30.95815652
55EGFR0.95727989
56NEK90.95531416
57MAP2K10.93239915
58TESK10.92494366
59LATS10.92275763
60TEC0.89991274
61ICK0.84598126
62CDK60.83998826
63STK30.83082871
64CAMKK10.81491483
65PRKCI0.80548574
66PTK2B0.79568613
67PDGFRA0.78126261
68TTN0.76549227
69STK380.75780398
70ITK0.74479703
71TLK10.74428542
72PNCK0.71347134
73ERBB20.67249028
74MAP3K10.66612265
75SRC0.63967922
76DAPK30.63326339
77TBK10.62665529
78DAPK10.61218150
79BMX0.59203810
80NTRK10.58371890
81ABL10.58149250
82IGF1R0.57050978
83RPS6KB20.52196963
84MAP2K20.49682580
85RET0.48951485
86DDR20.48446811
87CDC42BPA0.48443390
88FGFR10.48235145
89PRKG20.47528977
90CAMK2G0.47086805
91BLK0.46961647
92BRSK20.46908796
93PRKCH0.46175020
94PAK30.45251371
95FGR0.45071444
96SCYL20.44756103
97PRKCQ0.43248978
98TAOK10.42161828
99NLK0.41781605
100ROCK20.41718688
101MAPK150.41524397
102FYN0.41429929
103GSK3A0.39873000
104IRAK10.39605691
105STK160.39054610
106JAK10.38957262
107JAK20.38080868
108PRKAA20.37589204
109SGK10.36929764
110TYRO30.36118130
111AURKA0.35699923
112LIMK10.35627029
113CAMKK20.35224682
114PRKCE0.29535831
115RPS6KA20.29497095
116PHKG20.29440779
117PHKG10.29440779
118GRK60.29407729
119PBK0.28878056
120STK390.27987646
121BTK0.27807941
122BCR0.27459544
123PRKCD0.26894651
124CAMK1D0.26846046
125STK38L0.25703582
126DYRK1B0.25173065
127HIPK20.24962061
128MAP3K70.23795002
129ROCK10.23306206
130CSNK1G20.23092886
131MAPKAPK50.21882812
132AKT20.20836035
133MAP2K40.19130849
134PRKCA0.18325216
135MAP3K60.16887459
136PRKACA0.16885820
137MAP3K40.15541173
138PAK10.14839260
139PIM20.14382857
140DYRK1A0.13843420
141ABL20.12357432
142PDK10.12206579
143ADRBK10.11126885
144PRKD20.11079842
145PLK10.09745594
146PRKD30.09242202
147MAP3K80.09044844

Predicted pathways (KEGG)

RankGene SetZ-score
1Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009805.05648565
2Drug metabolism - cytochrome P450_Homo sapiens_hsa009825.02457967
3Chemical carcinogenesis_Homo sapiens_hsa052044.14231805
4Glutathione metabolism_Homo sapiens_hsa004803.20180325
5Histidine metabolism_Homo sapiens_hsa003402.59560797
6Phenylalanine metabolism_Homo sapiens_hsa003602.40579036
7Huntingtons disease_Homo sapiens_hsa050162.29877419
8Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049602.22584367
9Tyrosine metabolism_Homo sapiens_hsa003501.92846168
10Adherens junction_Homo sapiens_hsa045201.82661606
11Retinol metabolism_Homo sapiens_hsa008301.75378704
12Sphingolipid metabolism_Homo sapiens_hsa006001.68258228
13Leukocyte transendothelial migration_Homo sapiens_hsa046701.67178008
14Linoleic acid metabolism_Homo sapiens_hsa005911.63069335
15Tight junction_Homo sapiens_hsa045301.55562501
16Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005331.53651445
17Fatty acid degradation_Homo sapiens_hsa000711.49952146
18beta-Alanine metabolism_Homo sapiens_hsa004101.48960013
19Salivary secretion_Homo sapiens_hsa049701.45116204
20Bacterial invasion of epithelial cells_Homo sapiens_hsa051001.41053605
21Steroid hormone biosynthesis_Homo sapiens_hsa001401.33903622
22ECM-receptor interaction_Homo sapiens_hsa045121.32607126
23Mineral absorption_Homo sapiens_hsa049781.28969430
24Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006011.26697227
25Carbohydrate digestion and absorption_Homo sapiens_hsa049731.24245497
26Pathogenic Escherichia coli infection_Homo sapiens_hsa051301.23062758
27AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049331.16909204
28Caffeine metabolism_Homo sapiens_hsa002321.16085392
29Nitrogen metabolism_Homo sapiens_hsa009101.14649441
30ABC transporters_Homo sapiens_hsa020101.14052015
31Cell adhesion molecules (CAMs)_Homo sapiens_hsa045141.12516599
32Focal adhesion_Homo sapiens_hsa045101.12332989
33Pertussis_Homo sapiens_hsa051331.12058340
34Sulfur metabolism_Homo sapiens_hsa009201.11702461
35Glycolysis / Gluconeogenesis_Homo sapiens_hsa000101.11590451
36Starch and sucrose metabolism_Homo sapiens_hsa005001.10726178
37Renal cell carcinoma_Homo sapiens_hsa052111.07080934
38Peroxisome_Homo sapiens_hsa041461.03288703
39Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005121.02882438
40Tryptophan metabolism_Homo sapiens_hsa003801.00728328
41Arachidonic acid metabolism_Homo sapiens_hsa005901.00540834
42Phagosome_Homo sapiens_hsa041451.00137847
43Bladder cancer_Homo sapiens_hsa052190.98876242
44Circadian rhythm_Homo sapiens_hsa047100.97372075
45VEGF signaling pathway_Homo sapiens_hsa043700.94683834
46Lysosome_Homo sapiens_hsa041420.92411671
47Proteoglycans in cancer_Homo sapiens_hsa052050.91059795
48Hippo signaling pathway_Homo sapiens_hsa043900.87717480
49Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049640.86529862
50Bile secretion_Homo sapiens_hsa049760.85962097
51Platelet activation_Homo sapiens_hsa046110.85697466
52Amoebiasis_Homo sapiens_hsa051460.85263021
53Salmonella infection_Homo sapiens_hsa051320.83202550
54Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.80858830
55Complement and coagulation cascades_Homo sapiens_hsa046100.79531369
56Rap1 signaling pathway_Homo sapiens_hsa040150.77704457
57Gastric acid secretion_Homo sapiens_hsa049710.72625012
58Thyroid cancer_Homo sapiens_hsa052160.71889391
59Selenocompound metabolism_Homo sapiens_hsa004500.71381292
60Vasopressin-regulated water reabsorption_Homo sapiens_hsa049620.71251730
61Endocytosis_Homo sapiens_hsa041440.70245139
62Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054120.70074482
63Pancreatic cancer_Homo sapiens_hsa052120.69718083
64Drug metabolism - other enzymes_Homo sapiens_hsa009830.69243256
65Malaria_Homo sapiens_hsa051440.67895415
66Toxoplasmosis_Homo sapiens_hsa051450.67354807
67Notch signaling pathway_Homo sapiens_hsa043300.66288869
68Small cell lung cancer_Homo sapiens_hsa052220.66159890
69Renin secretion_Homo sapiens_hsa049240.66140897
70Vibrio cholerae infection_Homo sapiens_hsa051100.65880517
71Shigellosis_Homo sapiens_hsa051310.65746529
72Axon guidance_Homo sapiens_hsa043600.64457076
73Choline metabolism in cancer_Homo sapiens_hsa052310.63987130
74Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001300.63089753
75Regulation of actin cytoskeleton_Homo sapiens_hsa048100.61791869
76Allograft rejection_Homo sapiens_hsa053300.60450328
77Dorso-ventral axis formation_Homo sapiens_hsa043200.60118842
78Asthma_Homo sapiens_hsa053100.59893106
79Type I diabetes mellitus_Homo sapiens_hsa049400.58176764
80Hematopoietic cell lineage_Homo sapiens_hsa046400.57260526
81Thyroid hormone synthesis_Homo sapiens_hsa049180.56859848
82Autoimmune thyroid disease_Homo sapiens_hsa053200.56309037
83Cyanoamino acid metabolism_Homo sapiens_hsa004600.55874700
84Fatty acid biosynthesis_Homo sapiens_hsa000610.55872147
85Viral myocarditis_Homo sapiens_hsa054160.54865459
86Glycerophospholipid metabolism_Homo sapiens_hsa005640.54844548
87Endometrial cancer_Homo sapiens_hsa052130.52572520
88TGF-beta signaling pathway_Homo sapiens_hsa043500.51771208
89Chagas disease (American trypanosomiasis)_Homo sapiens_hsa051420.51225017
90Graft-versus-host disease_Homo sapiens_hsa053320.51175228
91Inflammatory bowel disease (IBD)_Homo sapiens_hsa053210.50221787
92Fatty acid metabolism_Homo sapiens_hsa012120.49426332
93Primary bile acid biosynthesis_Homo sapiens_hsa001200.48146914
94Fatty acid elongation_Homo sapiens_hsa000620.47373747
95Chronic myeloid leukemia_Homo sapiens_hsa052200.45893469
96Taste transduction_Homo sapiens_hsa047420.45426948
97Collecting duct acid secretion_Homo sapiens_hsa049660.45185037
98Hepatitis C_Homo sapiens_hsa051600.45055941
99Pentose and glucuronate interconversions_Homo sapiens_hsa000400.43312286
100PPAR signaling pathway_Homo sapiens_hsa033200.41722514
101Intestinal immune network for IgA production_Homo sapiens_hsa046720.41167314
102Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054100.40591430
103Pathways in cancer_Homo sapiens_hsa052000.39817408
104Adipocytokine signaling pathway_Homo sapiens_hsa049200.39008217
105Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.38814025
106Sphingolipid signaling pathway_Homo sapiens_hsa040710.38046947
107Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.37869951
108Dilated cardiomyopathy_Homo sapiens_hsa054140.37639823
109Tuberculosis_Homo sapiens_hsa051520.36619284
110Sulfur relay system_Homo sapiens_hsa041220.36297880
111Hedgehog signaling pathway_Homo sapiens_hsa043400.34743168
112Rheumatoid arthritis_Homo sapiens_hsa053230.33694418
113Staphylococcus aureus infection_Homo sapiens_hsa051500.31959696
114Taurine and hypotaurine metabolism_Homo sapiens_hsa004300.31650761
115Vascular smooth muscle contraction_Homo sapiens_hsa042700.31490155
116Transcriptional misregulation in cancer_Homo sapiens_hsa052020.30817683
117Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010400.30814083
118Pentose phosphate pathway_Homo sapiens_hsa000300.30378802
119Glycosaminoglycan degradation_Homo sapiens_hsa005310.30261190
120Leishmaniasis_Homo sapiens_hsa051400.29832232
121Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.29693019
122Olfactory transduction_Homo sapiens_hsa047400.29154426
123Ascorbate and aldarate metabolism_Homo sapiens_hsa000530.28584006
124Renin-angiotensin system_Homo sapiens_hsa046140.28554105
125Antigen processing and presentation_Homo sapiens_hsa046120.27508545
126Melanogenesis_Homo sapiens_hsa049160.27310296
127Acute myeloid leukemia_Homo sapiens_hsa052210.26445437
128Basal cell carcinoma_Homo sapiens_hsa052170.26099743
129Estrogen signaling pathway_Homo sapiens_hsa049150.25543073
130B cell receptor signaling pathway_Homo sapiens_hsa046620.24411648
131Gap junction_Homo sapiens_hsa045400.23169081
132Insulin resistance_Homo sapiens_hsa049310.22797470
133Valine, leucine and isoleucine degradation_Homo sapiens_hsa002800.22687617
134Prion diseases_Homo sapiens_hsa050200.22648473
135Metabolic pathways_Homo sapiens_hsa011000.21923930
136Jak-STAT signaling pathway_Homo sapiens_hsa046300.21806312
137Pancreatic secretion_Homo sapiens_hsa049720.21306090
138Arginine and proline metabolism_Homo sapiens_hsa003300.20924392
139Cocaine addiction_Homo sapiens_hsa050300.18980229
140Vitamin digestion and absorption_Homo sapiens_hsa049770.18318761
141Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047500.17695570
142Synthesis and degradation of ketone bodies_Homo sapiens_hsa000720.16965833
143cAMP signaling pathway_Homo sapiens_hsa040240.16425392
144Phosphatidylinositol signaling system_Homo sapiens_hsa040700.12790417
145Serotonergic synapse_Homo sapiens_hsa047260.12536490
146RIG-I-like receptor signaling pathway_Homo sapiens_hsa046220.10690264
147Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.10629883
148Glycerolipid metabolism_Homo sapiens_hsa005610.09015559
149Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.08959443
150Influenza A_Homo sapiens_hsa051640.06884519
151Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.05990087
152Apoptosis_Homo sapiens_hsa042100.05305260

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