SAXO1

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1acrosome reaction (GO:0007340)9.79082646
2binding of sperm to zona pellucida (GO:0007339)9.72360481
3cell-cell recognition (GO:0009988)9.48162991
4plasma membrane fusion (GO:0045026)9.22656165
5reproduction (GO:0000003)8.86666537
6epithelial cilium movement (GO:0003351)8.85200684
7axonemal dynein complex assembly (GO:0070286)8.84891474
8cilium or flagellum-dependent cell motility (GO:0001539)8.72506769
9spermatid development (GO:0007286)8.63851218
10regulation of female gonad development (GO:2000194)8.38833774
11motile cilium assembly (GO:0044458)8.28195037
12regulation of cilium movement (GO:0003352)7.80029617
13regulation of acrosome reaction (GO:0060046)7.77556689
14piRNA metabolic process (GO:0034587)7.28025102
15cilium movement (GO:0003341)7.13622542
16male meiosis (GO:0007140)6.96724773
17synaptonemal complex assembly (GO:0007130)6.86135119
18synaptonemal complex organization (GO:0070193)6.82043275
19single fertilization (GO:0007338)6.80149921
20epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287)6.60591691
21regulation of DNA methylation (GO:0044030)6.58564653
22oocyte development (GO:0048599)6.37022182
23microtubule depolymerization (GO:0007019)6.21612464
24sperm capacitation (GO:0048240)6.11840335
25spermatogenesis (GO:0007283)5.82268023
26male gamete generation (GO:0048232)5.80797827
27fertilization (GO:0009566)5.80036496
28negative regulation of inclusion body assembly (GO:0090084)5.70896241
29regulation of histone H3-K9 methylation (GO:0051570)5.55886372
30gamete generation (GO:0007276)5.38488542
31negative regulation of histone methylation (GO:0031061)5.35434269
32histone H3-K9 demethylation (GO:0033169)5.22910752
33protein kinase C signaling (GO:0070528)5.21193326
34regulation of inclusion body assembly (GO:0090083)5.12121651
35organic cation transport (GO:0015695)5.01463139
36male meiosis I (GO:0007141)4.97231107
37retinal cone cell development (GO:0046549)4.92605253
38chromosome organization involved in meiosis (GO:0070192)4.88399187
39DNA methylation involved in gamete generation (GO:0043046)4.85433943
40germ cell development (GO:0007281)4.83000055
41cellular process involved in reproduction in multicellular organism (GO:0022412)4.79179517
42positive regulation of gastrulation (GO:2000543)4.78520688
43microtubule severing (GO:0051013)4.62643082
44spermatid nucleus differentiation (GO:0007289)4.60145663
45meiotic nuclear division (GO:0007126)4.58999775
46regulation of microtubule-based movement (GO:0060632)4.58821396
47positive regulation of histone H3-K4 methylation (GO:0051571)4.55184874
48negative regulation of reproductive process (GO:2000242)4.51902832
49rRNA methylation (GO:0031167)4.50760386
50female gamete generation (GO:0007292)4.49290599
51chromosome condensation (GO:0030261)4.47927788
52protein targeting to Golgi (GO:0000042)4.41878907
53cell recognition (GO:0008037)4.40198367
54ventricular system development (GO:0021591)4.37600381
55calcium ion-dependent exocytosis (GO:0017156)4.37162529
56meiosis I (GO:0007127)4.36388744
57retrograde transport, vesicle recycling within Golgi (GO:0000301)4.30151796
58DNA packaging (GO:0006323)4.23273060
59establishment of protein localization to Golgi (GO:0072600)4.22239845
60multicellular organismal reproductive process (GO:0048609)4.21736905
61chaperone-mediated protein complex assembly (GO:0051131)4.18980922
62positive regulation of calcium ion-dependent exocytosis (GO:0045956)4.18452876
63interferon-gamma secretion (GO:0072643)4.15792627
64glycine transport (GO:0015816)4.15463867
65single strand break repair (GO:0000012)4.14352621
66seminiferous tubule development (GO:0072520)4.11373259
67glycerol ether metabolic process (GO:0006662)4.09466919
68rRNA modification (GO:0000154)4.07971773
69regulation of steroid hormone secretion (GO:2000831)4.04174782
70monoubiquitinated protein deubiquitination (GO:0035520)4.02329573
71positive regulation of humoral immune response (GO:0002922)3.98083600
72positive regulation of meiosis (GO:0045836)3.94324721
73response to pheromone (GO:0019236)3.94096279
74negative regulation of retinoic acid receptor signaling pathway (GO:0048387)3.87213791
75cellular response to pH (GO:0071467)3.86006525
76ether metabolic process (GO:0018904)3.77145281
77regulation of spindle checkpoint (GO:0090231)3.76448542
78positive regulation of meiotic cell cycle (GO:0051446)3.73260018
79RNA destabilization (GO:0050779)3.68040539
80meiotic cell cycle (GO:0051321)3.66878626
81phosphatidylethanolamine biosynthetic process (GO:0006646)3.60228526
82regulation of cell maturation (GO:1903429)3.57177102
83sexual reproduction (GO:0019953)3.56622042
84positive regulation of histone methylation (GO:0031062)3.55362980
85regulation of meiosis (GO:0040020)3.51816164
86response to acidic pH (GO:0010447)3.44905619
87protein polyglutamylation (GO:0018095)3.44249885
88phosphatidylethanolamine metabolic process (GO:0046337)3.43906588
89positive regulation of endothelial cell differentiation (GO:0045603)3.41587806
90positive regulation of mitotic metaphase/anaphase transition (GO:0045842)3.33722250
91positive regulation of metaphase/anaphase transition of cell cycle (GO:1902101)3.33722250
92positive regulation of mitotic sister chromatid separation (GO:1901970)3.33722250
93nucleoside diphosphate phosphorylation (GO:0006165)3.33565032
94meiotic cell cycle process (GO:1903046)3.33326126
95microtubule polymerization or depolymerization (GO:0031109)3.30568818
96left/right pattern formation (GO:0060972)3.30080966
97somite rostral/caudal axis specification (GO:0032525)3.29866286
98regulation of retinoic acid receptor signaling pathway (GO:0048385)3.25408033
99genitalia morphogenesis (GO:0035112)3.25290124
100multicellular organismal development (GO:0007275)3.23634051
101centrosome duplication (GO:0051298)3.21444514
102nucleus organization (GO:0006997)3.15189503
103cellular ketone body metabolic process (GO:0046950)3.14736400
104DNA methylation (GO:0006306)3.10016953
105DNA alkylation (GO:0006305)3.10016953
106histone exchange (GO:0043486)3.07798633
107protein localization to chromosome, centromeric region (GO:0071459)3.01996135
108synapsis (GO:0007129)2.98864523
109polyol catabolic process (GO:0046174)2.98670298
110alditol metabolic process (GO:0019400)2.93969187
111protein refolding (GO:0042026)2.93898467
112protein K11-linked deubiquitination (GO:0035871)2.92392274
113gene silencing by RNA (GO:0031047)2.91551465
114GTP biosynthetic process (GO:0006183)2.88793973
115mitotic sister chromatid cohesion (GO:0007064)2.88452861
116polyamine biosynthetic process (GO:0006596)2.83597480
117centriole assembly (GO:0098534)2.75445383
118regulation of centriole replication (GO:0046599)2.74099466
119nuclear pore complex assembly (GO:0051292)2.69943997
120UTP biosynthetic process (GO:0006228)2.66207013
121DNA replication-dependent nucleosome organization (GO:0034723)2.63255340
122DNA replication-dependent nucleosome assembly (GO:0006335)2.63255340
123fructose metabolic process (GO:0006000)2.58991142
124centriole replication (GO:0007099)2.53201390
125protein complex localization (GO:0031503)2.52197042
126gene silencing (GO:0016458)2.49773686
127regulation of meiosis I (GO:0060631)2.48332314
128glycolytic process (GO:0006096)2.48121854
129carnitine transport (GO:0015879)2.47248526
130amino-acid betaine transport (GO:0015838)2.47248526
131microtubule-based movement (GO:0007018)2.44370380
132cilium organization (GO:0044782)2.44236040
133guanosine-containing compound biosynthetic process (GO:1901070)2.42972999
134chromatin silencing (GO:0006342)2.42616456
135blastocyst development (GO:0001824)2.41081651
136nuclear pore organization (GO:0006999)2.40631822
137peptidyl-threonine dephosphorylation (GO:0035970)2.39294652
138fusion of sperm to egg plasma membrane (GO:0007342)12.1748031
139cell wall macromolecule catabolic process (GO:0016998)12.0758077
140cell wall macromolecule metabolic process (GO:0044036)12.0758077
141sperm motility (GO:0030317)11.7393853
142sperm-egg recognition (GO:0035036)10.6190106
143multicellular organism reproduction (GO:0032504)10.3810782
144acrosome assembly (GO:0001675)10.3097783

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse5.00455507
2TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse3.89679292
3CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human3.15588487
4BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse2.58017033
5CREM_20920259_ChIP-Seq_GC1-SPG_Mouse2.55777597
6TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat2.41012779
7STAT6_21828071_ChIP-Seq_BEAS2B_Human2.31726542
8KAP1_22055183_ChIP-Seq_ESCs_Mouse2.26206614
9EZH2_22144423_ChIP-Seq_EOC_Human2.23806027
10FLI1_27457419_Chip-Seq_LIVER_Mouse2.21650488
11GLI1_17442700_ChIP-ChIP_MESCs_Mouse2.17172225
12SOX9_22984422_ChIP-ChIP_TESTIS_Rat2.16868753
13PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse2.16378648
14TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse2.10718910
15POU5F1_26923725_Chip-Seq_MESODERM_Mouse2.10718910
16GATA1_26923725_Chip-Seq_HPCs_Mouse2.10207408
17MYCN_21190229_ChIP-Seq_SHEP-21N_Human2.03920151
18MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse10.0564863
19CTBP2_25329375_ChIP-Seq_LNCAP_Human1.98927182
20GBX2_23144817_ChIP-Seq_PC3_Human1.96382645
21VDR_22108803_ChIP-Seq_LS180_Human1.96273365
22PCGF2_27294783_Chip-Seq_ESCs_Mouse1.93233043
23TP63_19390658_ChIP-ChIP_HaCaT_Human1.88114278
24UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human1.84877911
25KLF4_25985364_ChIP-Seq_ATHEROSCLEROSIS_LESION_Mouse1.83497732
26HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse1.78991164
27FOXM1_23109430_ChIP-Seq_U2OS_Human1.72329082
28AR_25329375_ChIP-Seq_VCAP_Human1.72158928
29CTBP1_25329375_ChIP-Seq_LNCAP_Human1.71632512
30SMAD4_21741376_ChIP-Seq_EPCs_Human1.68440674
31FLI1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.67489837
32STAT1_17558387_ChIP-Seq_HELA_Human1.65731686
33EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human1.60268558
34ZFP322A_24550733_ChIP-Seq_MESCs_Mouse1.59564889
35ZNF274_21170338_ChIP-Seq_K562_Hela1.58128116
36E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse1.56350581
37TOP2B_26459242_ChIP-Seq_MCF-7_Human1.56234539
38GATA3_21867929_ChIP-Seq_CD8_Mouse1.55262816
39SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.53130291
40MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human1.51787971
41SOX2_22085726_ChIP-Seq_NPCs_Mouse1.48586010
42RCOR1_19997604_ChIP-ChIP_NEURONS_Mouse1.45224656
43GATA3_21867929_ChIP-Seq_TH1_Mouse1.43849595
44TAL1_21186366_ChIP-Seq_BM-HSCs_Mouse1.42471388
45SIN3B_21632747_ChIP-Seq_MESCs_Mouse1.41241641
46AUTS2_25519132_ChIP-Seq_293T-REX_Human1.40876934
47SMAD4_21799915_ChIP-Seq_A2780_Human1.40343788
48GATA2_21186366_ChIP-Seq_BM-HSCs_Mouse1.39147505
49SMAD3_21741376_ChIP-Seq_EPCs_Human1.38890388
50P300_19829295_ChIP-Seq_ESCs_Human1.38584945
51ELK4_26923725_Chip-Seq_MESODERM_Mouse1.34168181
52RUNX2_22187159_ChIP-Seq_PCA_Human1.34165832
53NFE2_27457419_Chip-Seq_LIVER_Mouse1.34034719
54FLI1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse1.32666738
55GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.32227307
56DROSHA_22980978_ChIP-Seq_HELA_Human1.31776729
57MEIS1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse1.31013467
58WDR5_24793694_ChIP-Seq_LNCAP_Human1.30719541
59BP1_19119308_ChIP-ChIP_Hs578T_Human1.30022166
60PCGF2_27294783_Chip-Seq_NPCs_Mouse1.29034243
61PRDM14_20953172_ChIP-Seq_ESCs_Human1.28104741
62ARNT_22903824_ChIP-Seq_MCF-7_Human1.27968216
63KLF2_18264089_ChIP-ChIP_MESCs_Mouse1.25725727
64KLF5_18264089_ChIP-ChIP_MESCs_Mouse1.25725727
65KLF4_18264089_ChIP-ChIP_MESCs_Mouse1.25725727
66LUZP1_20508642_ChIP-Seq_ESCs_Mouse1.25516876
67FUS_26573619_Chip-Seq_HEK293_Human1.25313575
68ER_23166858_ChIP-Seq_MCF-7_Human1.24919282
69STAT3_23295773_ChIP-Seq_U87_Human1.24904214
70TAL1_26923725_Chip-Seq_HPCs_Mouse1.23690261
71TCF4_23295773_ChIP-Seq_U87_Human1.22697090
72SUZ12_27294783_Chip-Seq_NPCs_Mouse1.21734476
73SMAD3_21741376_ChIP-Seq_ESCs_Human1.19281653
74P53_21459846_ChIP-Seq_SAOS-2_Human1.17694704
75RAC3_21632823_ChIP-Seq_H3396_Human1.17537005
76BMI1_23680149_ChIP-Seq_NPCS_Mouse1.17465566
77YY1_22570637_ChIP-Seq_MALME-3M_Human1.17317658
78TAF2_19829295_ChIP-Seq_ESCs_Human1.17241511
79CEBPB_26923725_Chip-Seq_MACROPHAGESS_Mouse1.17025592
80ERA_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human1.16205219
81SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.15661322
82SMRT_27268052_Chip-Seq_Bcells_Human1.15584304
83MYC_19829295_ChIP-Seq_ESCs_Human1.14721134
84SETDB1_19884257_ChIP-Seq_MESCs_Mouse1.14492832
85SPI1_26923725_Chip-Seq_HPCs_Mouse1.14190819
86NACC1_18358816_ChIP-ChIP_MESCs_Mouse1.13296182
87SPI1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.13274239
88FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human1.12798977
89KLF1_20508144_ChIP-Seq_FETAL-LIVER-ERYTHROID_Mouse1.12668419
90EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human1.12580801
91ERA_21632823_ChIP-Seq_H3396_Human1.12031806
92RARA_24833708_ChIP-Seq_LIVER_Mouse1.11392350
93EZH2_27304074_Chip-Seq_ESCs_Mouse1.10137702
94GATA3_21878914_ChIP-Seq_MCF-7_Human1.08126319
95CBX2_27304074_Chip-Seq_ESCs_Mouse1.08112856
96SMAD4_21741376_ChIP-Seq_HESCs_Human1.07777550
97KDM2B_26808549_Chip-Seq_REH_Human1.07719660
98CHD7_19251738_ChIP-ChIP_MESCs_Mouse1.07321697
99FOXH1_21741376_ChIP-Seq_EPCs_Human1.07247998
100ZFP42_18358816_ChIP-ChIP_MESCs_Mouse1.07179950
101FLI1_21867929_ChIP-Seq_CD8_Mouse1.06512775
102RUNX1_26923725_Chip-Seq_HPCs_Mouse1.05857187
103CEBPB_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse1.05319594
104CBP_21632823_ChIP-Seq_H3396_Human1.05182813
105SMAD1_18555785_ChIP-Seq_MESCs_Mouse1.04746252
106GF1_26923725_Chip-Seq_HPCs_Mouse1.04587512
107PPARG_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse1.04419463
108ESET_19884257_ChIP-Seq_ESCs_Mouse1.04051870
109TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.03994812
110JARID1A_20064375_ChIP-Seq_MESCs_Mouse1.03371866
111CRX_20693478_ChIP-Seq_RETINA_Mouse1.01503500
112LDB1_21186366_ChIP-Seq_BM-HSCs_Mouse1.01029455
113SIN3A_21632747_ChIP-Seq_MESCs_Mouse1.00766286
114SOX2_19829295_ChIP-Seq_ESCs_Human1.00720500
115NANOG_19829295_ChIP-Seq_ESCs_Human1.00720500
116CEBPB_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.00364739
117RXRA_24833708_ChIP-Seq_LIVER_Mouse1.00032760
118P63_20808887_ChIP-Seq_KERATINOCYTES_Human0.99234441
119AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human0.97909822
120IRF1_19129219_ChIP-ChIP_H3396_Human0.97828238
121KLF4_19829295_ChIP-Seq_ESCs_Human0.97692638
122TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse0.97014631
123OCT4_20526341_ChIP-Seq_ESCs_Human0.96933045
124EBNA1_20929547_Chip-Seq_RAJI-cells_Human0.96911865
125OCT4_18555785_Chip-Seq_ESCs_Mouse0.96046766
126KLF5_20875108_ChIP-Seq_MESCs_Mouse0.95203711
127IRF4_20064451_ChIP-Seq_CD4+T_Mouse0.94884820
128CBP_20019798_ChIP-Seq_JUKART_Human0.94884820
129CTCF_20526341_ChIP-Seq_ESCs_Human0.94823958
130PBX_27287812_Chip-Seq_EMBYONIC-LIMB_Mouse0.94349314
131KLF4_18555785_Chip-Seq_ESCs_Mouse0.94297565
132ERG_20517297_ChIP-Seq_VCAP_Human0.93840514
133VDR_20736230_ChIP-Seq_LYMPHOBLASTOID_Human0.93575876
134ETV1_20927104_ChIP-Seq_GIST48_Human0.93562272
135PHF8_20622854_ChIP-Seq_HELA_Human0.93523397
136RAD21_21589869_ChIP-Seq_MESCs_Mouse0.92391665
137FLI1_21867929_ChIP-Seq_TH2_Mouse0.91744242
138AHR_22903824_ChIP-Seq_MCF-7_Human0.91448245
139AR_21909140_ChIP-Seq_LNCAP_Human0.90478903
140SPI1_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse0.90462937
141RCOR3_21632747_ChIP-Seq_MESCs_Mouse0.90305294
142MYC_18358816_ChIP-ChIP_MESCs_Mouse0.89482219
143NFYB_21822215_ChIP-Seq_K562_Human0.89466285
144TET1_21451524_ChIP-Seq_MESCs_Mouse0.89364385
145CDX2_21402776_ChIP-Seq_INTESTINAL-VILLUS_Mouse0.88384587
146SUZ12_27294783_Chip-Seq_ESCs_Mouse0.87950219
147TAF15_26573619_Chip-Seq_HEK293_Human0.87614877
148NOTCH1_17114293_ChIP-ChIP_T-ALL_Human0.87186784
149PU.1_20176806_ChIP-Seq_MACROPHAGES_Mouse0.87153377
150REST_21632747_ChIP-Seq_MESCs_Mouse0.87089755
151CEBPB_26923725_Chip-Seq_MESODERM_Mouse0.86792213
152OCT1_27270436_Chip-Seq_PROSTATE_Human0.86753280
153ESRRB_18555785_Chip-Seq_ESCs_Mouse0.86533300
154TBL1_22424771_ChIP-Seq_293T_Human0.86425475
155GATA3_26560356_Chip-Seq_TH1_Human0.86398245
156E2F1_17053090_ChIP-ChIP_MCF-7_Human0.86285100
157BCOR_27268052_Chip-Seq_Bcells_Human0.86095939
158PBX1_22567123_ChIP-ChIP_OVCAR3_Human0.85992617
159GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse0.85854715
160PHF8_20622853_ChIP-Seq_HELA_Human0.85520233
161NANOG_18555785_Chip-Seq_ESCs_Mouse0.85403710
162NEUROD2_26341353_ChIP-Seq_CORTEX_Mouse0.84897527
163SALL4_22934838_ChIP-ChIP_CD34+_Human0.84688929
164STAT3_18555785_ChIP-Seq_MESCs_Mouse0.84400193
165TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human0.84369801
166NCOR_22424771_ChIP-Seq_293T_Human0.83930167
167EZH2_27294783_Chip-Seq_ESCs_Mouse0.83856874
168HOXB7_26014856_ChIP-Seq_BT474_Human0.83528398
169SALL1_21062744_ChIP-ChIP_HESCs_Human0.83089195
170MYCN_18555785_ChIP-Seq_MESCs_Mouse0.82620295
171P300_18555785_Chip-Seq_ESCs_Mouse0.80664247
172SOX2_21211035_ChIP-Seq_LN229_Human0.80317605
173NANOG_20526341_ChIP-Seq_ESCs_Human0.80076930
174OCT4_21477851_ChIP-Seq_ESCs_Mouse0.80029538
175EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse0.79868871
176CTCF_26484167_Chip-Seq_Bcells_Mouse0.79722898

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0003698_abnormal_male_reproductive5.57045666
2MP0001929_abnormal_gametogenesis5.40615100
3MP0008877_abnormal_DNA_methylation4.62648431
4MP0006292_abnormal_olfactory_placode4.30482490
5MP0002210_abnormal_sex_determination3.61869291
6MP0002161_abnormal_fertility/fecundity3.23378417
7MP0008789_abnormal_olfactory_epithelium3.20119613
8MP0001145_abnormal_male_reproductive3.10784167
9MP0002653_abnormal_ependyma_morphology3.06849377
10MP0000653_abnormal_sex_gland2.76015758
11MP0005499_abnormal_olfactory_system2.72431527
12MP0005394_taste/olfaction_phenotype2.72431527
13MP0002138_abnormal_hepatobiliary_system2.54126391
14MP0003693_abnormal_embryo_hatching2.45066945
15MP0005670_abnormal_white_adipose2.38336314
16MP0003111_abnormal_nucleus_morphology2.37825814
17MP0002139_abnormal_hepatobiliary_system2.24271831
18MP0008058_abnormal_DNA_repair2.23111584
19MP0003879_abnormal_hair_cell2.19449342
20MP0010094_abnormal_chromosome_stability2.17124638
21MP0010030_abnormal_orbit_morphology2.08042739
22MP0005410_abnormal_fertilization13.9917659
23MP0003646_muscle_fatigue1.80879815
24MP0003718_maternal_effect1.72630661
25MP0003890_abnormal_embryonic-extraembry1.72151683
26MP0004957_abnormal_blastocyst_morpholog1.70140172
27MP0005360_urolithiasis1.67942239
28MP0008057_abnormal_DNA_replication1.66198976
29MP0002160_abnormal_reproductive_system1.65530075
30MP0000678_abnormal_parathyroid_gland1.59048671
31MP0000566_synostosis1.53845165
32MP0003077_abnormal_cell_cycle1.51599381
33MP0005623_abnormal_meninges_morphology1.46988963
34MP0004233_abnormal_muscle_weight1.31540070
35MP0005646_abnormal_pituitary_gland1.31007050
36MP0005551_abnormal_eye_electrophysiolog1.25509149
37MP0003786_premature_aging1.24257114
38MP0001730_embryonic_growth_arrest1.18777779
39MP0000049_abnormal_middle_ear1.15875949
40MP0005389_reproductive_system_phenotype1.11814495
41MP0002735_abnormal_chemical_nociception1.10597712
42MP0003878_abnormal_ear_physiology1.08230659
43MP0005377_hearing/vestibular/ear_phenot1.08230659
44MP0008932_abnormal_embryonic_tissue1.05639406
45MP0000631_abnormal_neuroendocrine_gland1.04210617
46MP0001963_abnormal_hearing_physiology1.02770220
47MP0003183_abnormal_peptide_metabolism1.02040224
48MP0008260_abnormal_autophagy0.99808026
49MP0002282_abnormal_trachea_morphology0.97834648
50MP0008007_abnormal_cellular_replicative0.94589815
51MP0000026_abnormal_inner_ear0.94320260
52MP0005451_abnormal_body_composition0.92803987
53MP0009840_abnormal_foam_cell0.92503091
54MP0003699_abnormal_female_reproductive0.91671125
55MP0005647_abnormal_sex_gland0.90121602
56MP0002102_abnormal_ear_morphology0.89319811
57MP0002127_abnormal_cardiovascular_syste0.87970869
58MP0001666_abnormal_nutrient_absorption0.87841292
59MP0003806_abnormal_nucleotide_metabolis0.86858166
60MP0008995_early_reproductive_senescence0.85681400
61MP0002272_abnormal_nervous_system0.85519897
62MP0001765_abnormal_ion_homeostasis0.85237143
63MP0003136_yellow_coat_color0.85163684
64MP0006276_abnormal_autonomic_nervous0.84986798
65MP0000358_abnormal_cell_content/0.84258148
66MP0004019_abnormal_vitamin_homeostasis0.83873301
67MP0005380_embryogenesis_phenotype0.82954528
68MP0001672_abnormal_embryogenesis/_devel0.82954528
69MP0001486_abnormal_startle_reflex0.82320419
70MP0001348_abnormal_lacrimal_gland0.80778712
71MP0005423_abnormal_somatic_nervous0.78425366
72MP0003950_abnormal_plasma_membrane0.77898406
73MP0001119_abnormal_female_reproductive0.77483826
74MP0004142_abnormal_muscle_tone0.77186015
75MP0002249_abnormal_larynx_morphology0.75912180
76MP0001485_abnormal_pinna_reflex0.75418101
77MP0005379_endocrine/exocrine_gland_phen0.74482416
78MP0001984_abnormal_olfaction0.73960229
79MP0002928_abnormal_bile_duct0.72820845
80MP0005395_other_phenotype0.72373885
81MP0001545_abnormal_hematopoietic_system0.71565454
82MP0005397_hematopoietic_system_phenotyp0.71565454
83MP0003121_genomic_imprinting0.70924506
84MP0000762_abnormal_tongue_morphology0.70923043
85MP0001697_abnormal_embryo_size0.69457356
86MP0003252_abnormal_bile_duct0.69235363
87MP0001293_anophthalmia0.66397472
88MP0002269_muscular_atrophy0.66271146
89MP0002233_abnormal_nose_morphology0.65664438
90MP0010368_abnormal_lymphatic_system0.65354539
91MP0003984_embryonic_growth_retardation0.65056688
92MP0009046_muscle_twitch0.64618160
93MP0002084_abnormal_developmental_patter0.63997600
94MP0000427_abnormal_hair_cycle0.63830969
95MP0002229_neurodegeneration0.63274339
96MP0002080_prenatal_lethality0.62051058
97MP0002088_abnormal_embryonic_growth/wei0.61472355
98MP0002085_abnormal_embryonic_tissue0.60853884
99MP0009278_abnormal_bone_marrow0.60509019
100MP0001764_abnormal_homeostasis0.59962532
101MP0010234_abnormal_vibrissa_follicle0.58640103
102MP0001661_extended_life_span0.58588121
103MP0000350_abnormal_cell_proliferation0.57332784
104MP0001664_abnormal_digestion0.57164081
105MP0010307_abnormal_tumor_latency0.56985453
106MP0002132_abnormal_respiratory_system0.56662382
107MP0000313_abnormal_cell_death0.56420972
108MP0009379_abnormal_foot_pigmentation0.53426144
109MP0002234_abnormal_pharynx_morphology0.53074617
110MP0000470_abnormal_stomach_morphology0.51516885
111MP0005310_abnormal_salivary_gland0.51312996
112MP0000733_abnormal_muscle_development0.50195934
113MP0001727_abnormal_embryo_implantation0.49183101
114MP0003115_abnormal_respiratory_system0.48355766
115MP0003011_delayed_dark_adaptation0.48349267
116MP0006036_abnormal_mitochondrial_physio0.47703753
117MP0003935_abnormal_craniofacial_develop0.47609191
118MP0006035_abnormal_mitochondrial_morpho0.47508296
119MP0003959_abnormal_lean_body0.46770309
120MP0002067_abnormal_sensory_capabilities0.46422789
121MP0003868_abnormal_feces_composition0.46172071
122MP0005636_abnormal_mineral_homeostasis0.45225217
123MP0005503_abnormal_tendon_morphology0.44755499
124MP0004742_abnormal_vestibular_system0.44207332
125MP0005666_abnormal_adipose_tissue0.43459341
126MP0002557_abnormal_social/conspecific_i0.42839751
127MP0009745_abnormal_behavioral_response0.42670617
128MP0001919_abnormal_reproductive_system0.41962778
129MP0001905_abnormal_dopamine_level0.41721242
130MP0003315_abnormal_perineum_morphology0.40509180
131MP0009672_abnormal_birth_weight0.39643559
132MP0002086_abnormal_extraembryonic_tissu0.39635386
133MP0000015_abnormal_ear_pigmentation0.39454741
134MP0001986_abnormal_taste_sensitivity0.38470158
135MP0002019_abnormal_tumor_incidence0.37280585
136MP0009697_abnormal_copulation0.33854015
137MP0003329_amyloid_beta_deposits0.33597816
138MP0001324_abnormal_eye_pigmentation0.32812842
139MP0004036_abnormal_muscle_relaxation0.32200372
140MP0003119_abnormal_digestive_system0.31683707
141MP0003861_abnormal_nervous_system0.31626838
142MP0004808_abnormal_hematopoietic_stem0.31275820
143MP0005391_vision/eye_phenotype0.30946112
144MP0004084_abnormal_cardiac_muscle0.30802166
145MP0002092_abnormal_eye_morphology0.30301011
146MP0003936_abnormal_reproductive_system0.30279923
147MP0002169_no_abnormal_phenotype0.28521814
148MP0004197_abnormal_fetal_growth/weight/0.28324776
149MP0002873_normal_phenotype0.27987089
150MP0004133_heterotaxia0.27171302
151MP0003123_paternal_imprinting0.27096416
152MP0005319_abnormal_enzyme/_coenzyme0.26906912
153MP0006072_abnormal_retinal_apoptosis0.26739492
154MP0009115_abnormal_fat_cell0.26138054
155MP0000001_mammalian_phenotype0.23270567
156MP0000432_abnormal_head_morphology0.20458533
157MP0005253_abnormal_eye_physiology0.19119867
158MP0009703_decreased_birth_body0.18137317

Predicted human phenotypes

RankGene SetZ-score
1Abnormal respiratory motile cilium physiology (HP:0012261)8.76911787
2Abnormal respiratory motile cilium morphology (HP:0005938)8.72650836
3Abnormal respiratory epithelium morphology (HP:0012253)8.72650836
4Rhinitis (HP:0012384)7.17633316
5Chronic bronchitis (HP:0004469)7.11678056
6Abnormal ciliary motility (HP:0012262)6.94584012
7Infertility (HP:0000789)6.65291066
8Nasal polyposis (HP:0100582)5.85207565
9Male infertility (HP:0003251)5.47878072
10Severe visual impairment (HP:0001141)5.21546499
11Abnormality of the nasal mucosa (HP:0000433)4.70680570
12Abnormality of abdominal situs (HP:0011620)4.67875896
13Abdominal situs inversus (HP:0003363)4.67875896
14Bronchitis (HP:0012387)4.31925810
15Aplasia/Hypoplasia of the fovea (HP:0008060)4.21944467
16Hypoplasia of the fovea (HP:0007750)4.21944467
17Primitive reflexes (palmomental, snout, glabellar) (HP:0002476)4.18894903
18Bronchiectasis (HP:0002110)4.17085112
19Osteomalacia (HP:0002749)4.13237779
20Abnormal spermatogenesis (HP:0008669)4.11981365
21Anterior segment dysgenesis (HP:0007700)4.04944229
22Attenuation of retinal blood vessels (HP:0007843)3.91156114
23Impulsivity (HP:0100710)3.84954909
24Hypophosphatemic rickets (HP:0004912)3.76902502
25Cone-rod dystrophy (HP:0000548)3.71606810
26Nephronophthisis (HP:0000090)3.71043275
27Bony spicule pigmentary retinopathy (HP:0007737)3.63210239
28Abnormality of macular pigmentation (HP:0008002)3.59125425
29Congenital sensorineural hearing impairment (HP:0008527)3.49848213
30Abnormality of the fovea (HP:0000493)3.40307631
31Lip pit (HP:0100267)3.31109125
32Chronic hepatic failure (HP:0100626)3.29082015
33Septo-optic dysplasia (HP:0100842)3.20183387
34Generalized aminoaciduria (HP:0002909)3.14580360
35Recurrent sinusitis (HP:0011108)3.12811386
36Recurrent otitis media (HP:0000403)3.12678318
37Truncal obesity (HP:0001956)3.11171755
38Parkinsonism with favorable response to dopaminergic medication (HP:0002548)3.05388849
39Abnormal rod and cone electroretinograms (HP:0008323)2.92086677
40Oligodactyly (hands) (HP:0001180)2.82857670
41Hyperkalemia (HP:0002153)2.79093416
42Abnormality of the renal medulla (HP:0100957)2.78280181
43Myokymia (HP:0002411)2.77804896
44Aplasia/Hypoplasia of the earlobes (HP:0009906)2.70049940
45Azoospermia (HP:0000027)2.68097888
46Abnormality of midbrain morphology (HP:0002418)2.68090984
47Molar tooth sign on MRI (HP:0002419)2.68090984
48Short tibia (HP:0005736)2.65630416
49Facial hemangioma (HP:0000329)2.56535958
50Aplasia/Hypoplasia of the macula (HP:0008059)2.53099081
51Resting tremor (HP:0002322)2.51610198
52Medial flaring of the eyebrow (HP:0010747)2.51316984
53Aplasia/Hypoplasia of the tibia (HP:0005772)2.48967361
54Recurrent bronchitis (HP:0002837)2.45424312
55Skin pits (HP:0100276)2.44500767
56Tubulointerstitial nephritis (HP:0001970)2.32612120
57Aplasia/Hypoplasia affecting the retina (HP:0008061)2.31233164
58Absent septum pellucidum (HP:0001331)2.30569823
59Aplasia/Hypoplasia of the optic nerve (HP:0008058)2.29178777
60Hypergonadotropic hypogonadism (HP:0000815)2.27284877
61Maternal diabetes (HP:0009800)2.26815031
62Gonadotropin excess (HP:0000837)2.23128000
63Tubular atrophy (HP:0000092)2.22163446
64Hypoplasia of the capital femoral epiphysis (HP:0003090)2.17687303
65Abnormality of the labia minora (HP:0012880)2.12817936
66Asymmetric septal hypertrophy (HP:0001670)2.11523452
67Subcapsular cataract (HP:0000523)2.11420310
68Premature ovarian failure (HP:0008209)2.10050142
69Congenital malformation of the right heart (HP:0011723)2.09647620
70Double outlet right ventricle (HP:0001719)2.09647620
71Tubulointerstitial abnormality (HP:0001969)2.07593039
72Pancreatic fibrosis (HP:0100732)2.02093941
73Papillary thyroid carcinoma (HP:0002895)2.01826368
74Aplasia of the musculature (HP:0100854)2.01742359
75Chromsome breakage (HP:0040012)2.01602692
76Respiratory insufficiency due to defective ciliary clearance (HP:0200073)12.8139852
77Dynein arm defect of respiratory motile cilia (HP:0012255)12.4897156
78Absent/shortened dynein arms (HP:0200106)12.4897156
79Tongue fasciculations (HP:0001308)1.99925334
80Facial shape deformation (HP:0011334)1.97239268
81Potter facies (HP:0002009)1.97239268
82Insulin-resistant diabetes mellitus (HP:0000831)1.97084596
83Chromosomal breakage induced by crosslinking agents (HP:0003221)1.94799069
84Facial cleft (HP:0002006)1.92287165
85Progressive cerebellar ataxia (HP:0002073)1.91066399
86Progressive sensorineural hearing impairment (HP:0000408)1.91047528
87Spastic tetraparesis (HP:0001285)1.89823554
88Renovascular hypertension (HP:0100817)1.89043071
89Sensory axonal neuropathy (HP:0003390)1.88282027
90Bell-shaped thorax (HP:0001591)1.88097799
91Bundle branch block (HP:0011710)1.86630360
92Malnutrition (HP:0004395)1.86623378
93Glycosuria (HP:0003076)1.86310047
94Abnormality of urine glucose concentration (HP:0011016)1.86310047
95Abnormality of the septum pellucidum (HP:0007375)1.85117315
96Postaxial foot polydactyly (HP:0001830)1.83997080
97Photophobia (HP:0000613)1.83369012
98Muscle fibrillation (HP:0010546)1.83023106
99Oligodactyly (HP:0012165)1.82385263
100Hypoalphalipoproteinemia (HP:0003233)1.80948561
101Increased circulating renin level (HP:0000848)1.80401110
102Preauricular pit (HP:0004467)1.80042081
103Periauricular skin pits (HP:0100277)1.80042081
104Neoplasm of the oral cavity (HP:0100649)1.79794829
105Renal Fanconi syndrome (HP:0001994)1.78539238
106Urethral obstruction (HP:0000796)1.78498893
107Apathy (HP:0000741)1.77915273
108Pendular nystagmus (HP:0012043)1.74864390
109Portal hypertension (HP:0001409)1.73805288
110Dysdiadochokinesis (HP:0002075)1.73420275
111Enlarged epiphyses (HP:0010580)1.73343707
112Tubulointerstitial fibrosis (HP:0005576)1.71844134
113Microglossia (HP:0000171)1.68417529
114Absent epiphyses (HP:0010577)1.66823245
115Aplasia/Hypoplasia of the capital femoral epiphysis (HP:0005003)1.66823245
116Congenital hepatic fibrosis (HP:0002612)1.65644031
117Decreased central vision (HP:0007663)1.56861816
118Oculomotor apraxia (HP:0000657)1.55916307
119Congenital primary aphakia (HP:0007707)1.55757500
120Short ribs (HP:0000773)1.54463573
121Abnormality of the renal cortex (HP:0011035)1.53087129
122Gait imbalance (HP:0002141)1.52578245
123Pancreatic cysts (HP:0001737)1.52277988
124Abnormal biliary tract physiology (HP:0012439)1.51801358
125Bile duct proliferation (HP:0001408)1.51801358
126Supernumerary spleens (HP:0009799)1.51646603
127Aplasia/Hypoplasia of the tongue (HP:0010295)1.50329007
128Sloping forehead (HP:0000340)1.49127066
129Heterotopia (HP:0002282)1.48799417
130Transposition of the great arteries (HP:0001669)1.45119215
131Abnormal connection of the cardiac segments (HP:0011545)1.45119215
132Abnormal ventriculo-arterial connection (HP:0011563)1.45119215
133Abnormality of permanent molar morphology (HP:0011071)1.45084698
134Abnormality of the dental root (HP:0006486)1.45084698
135Taurodontia (HP:0000679)1.45084698
136Cystic liver disease (HP:0006706)1.44585760
137Dyschromatopsia (HP:0007641)1.44427131
138Aplasia/Hypoplasia affecting the fundus (HP:0008057)1.44154047
139Type 2 muscle fiber atrophy (HP:0003554)1.43337316
140Ureteral duplication (HP:0000073)1.42111079
141Abnormality of renal excretion (HP:0011036)1.41595400
142Degeneration of anterior horn cells (HP:0002398)1.41038074
143Abnormality of the anterior horn cell (HP:0006802)1.41038074
144Carpal bone hypoplasia (HP:0001498)1.40700206
145Abnormal gallbladder physiology (HP:0012438)1.40390561
146Cholecystitis (HP:0001082)1.40390561
147Cleft eyelid (HP:0000625)1.39389151
148Poor coordination (HP:0002370)1.39163201
149Nephrogenic diabetes insipidus (HP:0009806)1.38244811
150Postaxial hand polydactyly (HP:0001162)1.38233457
151Median cleft lip (HP:0000161)1.37178669
152Personality changes (HP:0000751)1.36827480
153Short nail (HP:0001799)1.36827401
154Aplasia/Hypoplasia involving the carpal bones (HP:0006502)1.36558882
155Glucose intolerance (HP:0000833)1.36433499
156True hermaphroditism (HP:0010459)1.36357380
157Stage 5 chronic kidney disease (HP:0003774)1.36147725
158Abnormality of the umbilical cord (HP:0010881)1.34228500
159Abnormality of molar morphology (HP:0011070)1.32916011
160Abnormality of molar (HP:0011077)1.32916011
161Abnormality of the lower motor neuron (HP:0002366)1.32849278
162Difficulty climbing stairs (HP:0003551)1.32435111
163Aplasia/Hypoplasia of the lens (HP:0008063)1.32048452
164Fibular hypoplasia (HP:0003038)1.31301613
165Abnormality of the dental pulp (HP:0006479)1.28850967
166Optic nerve hypoplasia (HP:0000609)1.27785692
167Polydipsia (HP:0001959)1.27008226
168Abnormal drinking behavior (HP:0030082)1.27008226
169Birth length less than 3rd percentile (HP:0003561)1.26185971
170Meckel diverticulum (HP:0002245)1.26014851
171Renal dysplasia (HP:0000110)1.25609964

Predicted kinase interactions (KEA)

RankGene SetZ-score
1PDK38.40801754
2PDK48.40801754
3PDK25.51909153
4MAP3K94.47896251
5TESK14.44798349
6PRKD33.77167382
7MAP3K133.59698291
8ICK3.33174571
9PNCK2.85332126
10TAOK32.60809525
11BRD42.43662711
12WEE12.21859891
13NEK22.18528986
14INSRR2.10076376
15STK242.08758765
16BUB11.98701383
17DDR21.91923333
18CAMK1G1.82993865
19CDK91.80575236
20TNIK1.76682159
21MET1.74163232
22PLK21.67469045
23MOS1.63274464
24MAP4K21.56306576
25TTK1.55397435
26STK381.48952206
27STK391.45060355
28PTK2B1.43693459
29WNK41.35056429
30PLK41.33863201
31BMPR1B1.33628792
32DYRK31.25953654
33KSR21.24956242
34CHEK21.11628897
35BRSK21.10889732
36CCNB11.06173813
37STK38L1.04300369
38TLK11.03418041
39EIF2AK11.03036954
40STK160.97907555
41CDC70.97483943
42CAMK1D0.96789476
43PLK10.93956856
44PDK10.92251976
45DYRK1B0.90497953
46STK30.87885574
47TYRO30.85001056
48TESK20.83567596
49TIE10.82234017
50PRKCI0.81311100
51PRKG10.80925566
52PKN10.79041118
53NTRK30.76886375
54TRIM280.76132967
55BRAF0.75534548
56PASK0.75290172
57PIK3CG0.74770879
58RAF10.69376830
59VRK10.67361490
60CHEK10.65842121
61PAK10.64480616
62IRAK10.63509937
63TGFBR10.60759194
64CAMK10.57714973
65LATS20.57593553
66AURKA0.54900213
67BRSK10.54115388
68TNK20.53923359
69PINK10.53732494
70CDK190.53384201
71MAP2K60.51640811
72NUAK10.51378199
73MAPK150.50866012
74PDPK10.50592978
75ATR0.50438626
76PRKCZ0.48478354
77CSNK1D0.46757154
78ARAF0.46185108
79SRPK10.44174733
80PRKAA20.43977902
81PLK30.43848737
82OXSR10.43225901
83CDK40.42018644
84CDK80.41180968
85MAPK10.40937262
86NEK10.39870986
87ATM0.38535888
88AURKB0.37622556
89EIF2AK30.36665045
90EPHA20.35247718
91CSNK1G10.34236156
92PRKACA0.33714954
93AKT30.33616993
94MST40.32742618
95WNK10.31109016
96MAPK130.31102091
97MST1R0.30883372
98CAMK40.30245025
99PTK20.29815648
100LMTK20.29800354
101ACVR1B0.29285427
102CHUK0.28754545
103PRKCG0.28641477
104CSNK2A10.28419228
105CDK20.28067022
106PRKACB0.27456509
107IRAK20.26699553
108PRKAA10.26210037
109NEK90.25882600
110MTOR0.25808319
111MAP3K40.25644178
112MUSK0.25537810
113MAP3K80.25085538
114MELK0.23450534
115CSNK2A20.22805898
116ZAP700.21676361
117CDK10.20950165
118EEF2K0.18505207
119PIM10.18369197
120STK100.18284013
121MAP3K60.18181389
122CDK70.17980318
123PAK40.17530805
124MARK30.17449938
125NTRK20.16091478
126CSNK1E0.15813070
127MAP3K50.13618868
128DYRK20.13559185
129ZAK0.11569920
130WNK30.11372241
131RPS6KB10.10346791
132GSK3B0.10131668
133PAK20.09365544
134LATS10.09334939
135CDK120.08028278
136NME20.07507359
137TSSK60.07317269
138STK110.06810950
139RIPK40.06786007
140NEK60.06634193
141PIM20.06228392
142TAOK10.05990685
143MAPK100.05846006
144CDK11A0.05476024
145CDK150.05380532
146MKNK20.04499807
147CDK60.04395719
148RPS6KA10.04054459
149PBK0.03997171

Predicted pathways (KEGG)

RankGene SetZ-score
1Vitamin B6 metabolism_Homo sapiens_hsa007505.53100168
2Synthesis and degradation of ketone bodies_Homo sapiens_hsa000725.01368641
3Olfactory transduction_Homo sapiens_hsa047403.53746215
4Basal transcription factors_Homo sapiens_hsa030223.38876507
5Glycolysis / Gluconeogenesis_Homo sapiens_hsa000103.32537046
6Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005333.18211742
7Proteasome_Homo sapiens_hsa030503.03660679
8Ovarian steroidogenesis_Homo sapiens_hsa049133.01041282
9Fatty acid biosynthesis_Homo sapiens_hsa000612.90725117
10RNA transport_Homo sapiens_hsa030132.86511732
11Pentose phosphate pathway_Homo sapiens_hsa000302.69475070
12Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030082.47575076
13Caffeine metabolism_Homo sapiens_hsa002322.44527025
14Fanconi anemia pathway_Homo sapiens_hsa034602.41238298
15Pyruvate metabolism_Homo sapiens_hsa006202.39899768
16Linoleic acid metabolism_Homo sapiens_hsa005912.38438107
17alpha-Linolenic acid metabolism_Homo sapiens_hsa005922.32046764
18Oocyte meiosis_Homo sapiens_hsa041142.17959066
19Fructose and mannose metabolism_Homo sapiens_hsa000512.13972712
20Butirosin and neomycin biosynthesis_Homo sapiens_hsa005241.96827741
21Selenocompound metabolism_Homo sapiens_hsa004501.93978069
22Phototransduction_Homo sapiens_hsa047441.86504381
23Propanoate metabolism_Homo sapiens_hsa006401.84913298
24Glycerophospholipid metabolism_Homo sapiens_hsa005641.79623767
25DNA replication_Homo sapiens_hsa030301.75671517
26Cysteine and methionine metabolism_Homo sapiens_hsa002701.71613779
27Purine metabolism_Homo sapiens_hsa002301.69308987
28Pyrimidine metabolism_Homo sapiens_hsa002401.68087704
29mRNA surveillance pathway_Homo sapiens_hsa030151.65590292
30Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006011.63479158
31ABC transporters_Homo sapiens_hsa020101.62695876
32Cell cycle_Homo sapiens_hsa041101.61462475
33Taste transduction_Homo sapiens_hsa047421.54327347
34Homologous recombination_Homo sapiens_hsa034401.52922515
35Glucagon signaling pathway_Homo sapiens_hsa049221.52827573
36Carbon metabolism_Homo sapiens_hsa012001.50845863
37RNA polymerase_Homo sapiens_hsa030201.50245902
38Protein processing in endoplasmic reticulum_Homo sapiens_hsa041411.42744252
39Glycerolipid metabolism_Homo sapiens_hsa005611.42270272
40Mismatch repair_Homo sapiens_hsa034301.39754498
41Butanoate metabolism_Homo sapiens_hsa006501.36507161
42Base excision repair_Homo sapiens_hsa034101.34208132
43Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049641.33731442
44Glutathione metabolism_Homo sapiens_hsa004801.33531750
45Spliceosome_Homo sapiens_hsa030401.29349997
46Maturity onset diabetes of the young_Homo sapiens_hsa049501.28968664
47Nicotine addiction_Homo sapiens_hsa050331.25805811
48Ubiquitin mediated proteolysis_Homo sapiens_hsa041201.24166266
49Circadian rhythm_Homo sapiens_hsa047101.23989876
50Biosynthesis of amino acids_Homo sapiens_hsa012301.20854372
51Morphine addiction_Homo sapiens_hsa050321.20376261
52Carbohydrate digestion and absorption_Homo sapiens_hsa049731.19157098
53Mineral absorption_Homo sapiens_hsa049781.14272454
54Glycosaminoglycan degradation_Homo sapiens_hsa005311.12341073
55Nucleotide excision repair_Homo sapiens_hsa034201.08586838
56Ether lipid metabolism_Homo sapiens_hsa005651.07405077
57Gap junction_Homo sapiens_hsa045401.05952191
58Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007601.05781924
59PPAR signaling pathway_Homo sapiens_hsa033201.00353286
60Dorso-ventral axis formation_Homo sapiens_hsa043200.98353920
61Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.97780154
62Huntingtons disease_Homo sapiens_hsa050160.95312615
63Arachidonic acid metabolism_Homo sapiens_hsa005900.91556632
64Regulation of autophagy_Homo sapiens_hsa041400.91528202
65Antigen processing and presentation_Homo sapiens_hsa046120.89878946
66RNA degradation_Homo sapiens_hsa030180.89804485
67Citrate cycle (TCA cycle)_Homo sapiens_hsa000200.89710891
68Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.89681863
69Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.88896475
70Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.87620802
71Fat digestion and absorption_Homo sapiens_hsa049750.86430711
72Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.83838221
73cAMP signaling pathway_Homo sapiens_hsa040240.80237683
74GABAergic synapse_Homo sapiens_hsa047270.77434365
75Renin-angiotensin system_Homo sapiens_hsa046140.76524760
76Epstein-Barr virus infection_Homo sapiens_hsa051690.75660980
77Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006300.75286686
78Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.74824865
79Serotonergic synapse_Homo sapiens_hsa047260.74578224
80Hedgehog signaling pathway_Homo sapiens_hsa043400.74399652
81Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049610.72611906
82Folate biosynthesis_Homo sapiens_hsa007900.70692285
83Arginine biosynthesis_Homo sapiens_hsa002200.70592858
84Calcium signaling pathway_Homo sapiens_hsa040200.70328150
85Synaptic vesicle cycle_Homo sapiens_hsa047210.68253732
86Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.66844464
87Aldosterone synthesis and secretion_Homo sapiens_hsa049250.66040043
88Fatty acid metabolism_Homo sapiens_hsa012120.64148466
89Amphetamine addiction_Homo sapiens_hsa050310.62345254
90Collecting duct acid secretion_Homo sapiens_hsa049660.61855629
91Circadian entrainment_Homo sapiens_hsa047130.58298619
92TGF-beta signaling pathway_Homo sapiens_hsa043500.56957592
93Metabolic pathways_Homo sapiens_hsa011000.56657763
94p53 signaling pathway_Homo sapiens_hsa041150.56278387
95Type II diabetes mellitus_Homo sapiens_hsa049300.53220802
96Fatty acid degradation_Homo sapiens_hsa000710.52478631
97Sulfur relay system_Homo sapiens_hsa041220.51500676
98Insulin secretion_Homo sapiens_hsa049110.49000843
99Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.48158648
100mTOR signaling pathway_Homo sapiens_hsa041500.46591923
101Cardiac muscle contraction_Homo sapiens_hsa042600.44878494
102Adherens junction_Homo sapiens_hsa045200.44812151
103Lysine degradation_Homo sapiens_hsa003100.44701950
104Legionellosis_Homo sapiens_hsa051340.44411662
105Drug metabolism - cytochrome P450_Homo sapiens_hsa009820.43987996
106Vitamin digestion and absorption_Homo sapiens_hsa049770.43595717
107Pentose and glucuronate interconversions_Homo sapiens_hsa000400.42685557
108Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049600.42222623
109MAPK signaling pathway_Homo sapiens_hsa040100.41625541
110Salivary secretion_Homo sapiens_hsa049700.40407208
111Herpes simplex infection_Homo sapiens_hsa051680.39901290
112Chemical carcinogenesis_Homo sapiens_hsa052040.38334736
113Wnt signaling pathway_Homo sapiens_hsa043100.38069863
114Phenylalanine metabolism_Homo sapiens_hsa003600.37983180
115Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009700.37792388
116Non-homologous end-joining_Homo sapiens_hsa034500.37545317
117Thyroid cancer_Homo sapiens_hsa052160.36846990
118Influenza A_Homo sapiens_hsa051640.36338667
119Inositol phosphate metabolism_Homo sapiens_hsa005620.36311193
120Retrograde endocannabinoid signaling_Homo sapiens_hsa047230.35289551
121Cholinergic synapse_Homo sapiens_hsa047250.35202448
122cGMP-PKG signaling pathway_Homo sapiens_hsa040220.34525650
123AMPK signaling pathway_Homo sapiens_hsa041520.34310124
124Glutamatergic synapse_Homo sapiens_hsa047240.34073187
125Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.33846570
126Drug metabolism - other enzymes_Homo sapiens_hsa009830.33835733
127Endocytosis_Homo sapiens_hsa041440.28522165
128Transcriptional misregulation in cancer_Homo sapiens_hsa052020.28051925
129Oxytocin signaling pathway_Homo sapiens_hsa049210.24702614
130Thyroid hormone signaling pathway_Homo sapiens_hsa049190.23254481
131Adipocytokine signaling pathway_Homo sapiens_hsa049200.22304159
132Galactose metabolism_Homo sapiens_hsa000520.22183861
133Systemic lupus erythematosus_Homo sapiens_hsa053220.21851258
134FoxO signaling pathway_Homo sapiens_hsa040680.21368742
135Hippo signaling pathway_Homo sapiens_hsa043900.21321666
136Vascular smooth muscle contraction_Homo sapiens_hsa042700.21277564
137Allograft rejection_Homo sapiens_hsa053300.20493810
138Taurine and hypotaurine metabolism_Homo sapiens_hsa004300.20448618
139Estrogen signaling pathway_Homo sapiens_hsa049150.20389451
140Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.20039017
141Autoimmune thyroid disease_Homo sapiens_hsa053200.19356405
142Sphingolipid metabolism_Homo sapiens_hsa006000.18879272
143Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.17160707
144Viral carcinogenesis_Homo sapiens_hsa052030.15756664
145Central carbon metabolism in cancer_Homo sapiens_hsa052300.15015791
146Bile secretion_Homo sapiens_hsa049760.14965910
147Retinol metabolism_Homo sapiens_hsa008300.12617605
148Protein digestion and absorption_Homo sapiens_hsa049740.11254987
149Arginine and proline metabolism_Homo sapiens_hsa003300.10404508
150Tight junction_Homo sapiens_hsa045300.09035358
151Longevity regulating pathway - mammal_Homo sapiens_hsa042110.08982705
152Phosphatidylinositol signaling system_Homo sapiens_hsa040700.08371007

Most similar genes based on co-expression Upload to Enrichr

Tissue Expression Export image »

Cell Line Expression Export image »