SAMD13

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1axon ensheathment in central nervous system (GO:0032291)6.27582118
2central nervous system myelination (GO:0022010)6.27582118
3DNA replication-dependent nucleosome organization (GO:0034723)4.90930407
4DNA replication-dependent nucleosome assembly (GO:0006335)4.90930407
5limb bud formation (GO:0060174)4.38490119
6long-chain fatty acid biosynthetic process (GO:0042759)4.26872215
7positive regulation of amino acid transport (GO:0051957)4.15340638
8branched-chain amino acid catabolic process (GO:0009083)4.07973591
9replicative senescence (GO:0090399)4.05065281
10meiotic chromosome segregation (GO:0045132)4.02986157
11presynaptic membrane assembly (GO:0097105)3.97320653
12presynaptic membrane organization (GO:0097090)3.95560863
13somatic diversification of immune receptors via somatic mutation (GO:0002566)3.92915403
14somatic hypermutation of immunoglobulin genes (GO:0016446)3.92915403
15mitochondrial respiratory chain complex I biogenesis (GO:0097031)3.86910901
16mitochondrial respiratory chain complex I assembly (GO:0032981)3.86910901
17NADH dehydrogenase complex assembly (GO:0010257)3.86910901
18positive regulation of catecholamine secretion (GO:0033605)3.86663408
19negative regulation of execution phase of apoptosis (GO:1900118)3.77200448
20pyrimidine deoxyribonucleotide catabolic process (GO:0009223)3.64864755
21positive regulation of inositol phosphate biosynthetic process (GO:0060732)3.62149662
22DNA replication checkpoint (GO:0000076)3.56834484
23neuron cell-cell adhesion (GO:0007158)3.54821829
24protein complex biogenesis (GO:0070271)3.52822527
25cerebral cortex radially oriented cell migration (GO:0021799)3.50810307
26ribosome assembly (GO:0042255)3.45236925
27regulation of timing of cell differentiation (GO:0048505)3.43794929
28GTP biosynthetic process (GO:0006183)3.43227104
29retina layer formation (GO:0010842)3.43143957
30keratinocyte development (GO:0003334)3.41448917
31mitochondrial respiratory chain complex assembly (GO:0033108)3.39643728
32photoreceptor cell differentiation (GO:0046530)3.37484687
33eye photoreceptor cell differentiation (GO:0001754)3.37484687
34serotonin receptor signaling pathway (GO:0007210)3.30931498
35cranial nerve morphogenesis (GO:0021602)3.27799729
36cullin deneddylation (GO:0010388)3.25978400
37base-excision repair, AP site formation (GO:0006285)3.24432341
38pyrimidine deoxyribonucleotide metabolic process (GO:0009219)3.20248569
39import into cell (GO:0098657)3.19791907
40myelination (GO:0042552)3.18988940
41fatty acid elongation (GO:0030497)3.18067488
42organ growth (GO:0035265)3.14770081
43positive regulation of prostaglandin secretion (GO:0032308)3.13955700
44UTP metabolic process (GO:0046051)3.13952404
45L-amino acid import (GO:0043092)3.13317035
46guanosine-containing compound biosynthetic process (GO:1901070)3.13022264
47UTP biosynthetic process (GO:0006228)3.11903480
48axon ensheathment (GO:0008366)3.10851436
49ensheathment of neurons (GO:0007272)3.10851436
50neuron remodeling (GO:0016322)3.07654337
51proteasome assembly (GO:0043248)3.06977401
52mesenchymal cell differentiation involved in kidney development (GO:0072161)3.06538165
53mesenchymal cell differentiation involved in renal system development (GO:2001012)3.06538165
54DNA integration (GO:0015074)3.05644348
55righting reflex (GO:0060013)3.05197694
56postsynaptic membrane organization (GO:0001941)3.04961212
57L-methionine biosynthetic process from methylthioadenosine (GO:0019509)3.02693747
58branched-chain amino acid metabolic process (GO:0009081)2.99637472
59muscle cell fate commitment (GO:0042693)2.99198425
60positive regulation of action potential (GO:0045760)2.98140024
61innate immune response in mucosa (GO:0002227)2.98134414
62positive regulation of organic acid transport (GO:0032892)2.97695710
63pyrimidine nucleoside triphosphate metabolic process (GO:0009147)2.96285407
64negative regulation of amino acid transport (GO:0051956)2.94165703
65regulation of cell-cell adhesion mediated by cadherin (GO:2000047)2.93993225
66regulation of pigment cell differentiation (GO:0050932)2.93483890
67regulation of development, heterochronic (GO:0040034)2.92824174
68short-term memory (GO:0007614)2.91797752
69oligodendrocyte differentiation (GO:0048709)2.90139873
70ionotropic glutamate receptor signaling pathway (GO:0035235)2.89469244
71histone H2B ubiquitination (GO:0033523)2.88657510
72pyrimidine nucleotide catabolic process (GO:0006244)2.88494544
73negative regulation of protein localization to cell surface (GO:2000009)2.88194080
74CTP metabolic process (GO:0046036)2.87939269
75CTP biosynthetic process (GO:0006241)2.87939269
76cranial nerve development (GO:0021545)2.86806998
77translesion synthesis (GO:0019985)2.85899267
78formation of translation preinitiation complex (GO:0001731)2.84111563
79tryptophan metabolic process (GO:0006568)2.83002718
80negative regulation of synaptic transmission, GABAergic (GO:0032229)2.82139861
81negative regulation of neurotransmitter transport (GO:0051589)2.79652230
82regulation of inositol phosphate biosynthetic process (GO:0010919)2.79488598
83glycerophospholipid catabolic process (GO:0046475)2.77975398
84transmission of nerve impulse (GO:0019226)2.77555758
85protein deneddylation (GO:0000338)2.77424553
86nucleobase-containing small molecule interconversion (GO:0015949)2.77084145
87forebrain neuron differentiation (GO:0021879)2.76190821
88indolalkylamine metabolic process (GO:0006586)2.74809383
89pyrimidine nucleoside triphosphate biosynthetic process (GO:0009148)2.74446240
90GPI anchor biosynthetic process (GO:0006506)2.72784236
91pyrimidine ribonucleoside triphosphate metabolic process (GO:0009208)2.72188209
92response to stimulus involved in regulation of muscle adaptation (GO:0014874)2.72186579
93neuronal action potential propagation (GO:0019227)2.71474583
94pharyngeal system development (GO:0060037)2.70881085
95spinal cord motor neuron differentiation (GO:0021522)2.70092085
96regulation of glutamate secretion (GO:0014048)2.68801212
97pyrimidine ribonucleoside triphosphate biosynthetic process (GO:0009209)2.68388198
98glutamate receptor signaling pathway (GO:0007215)2.67867847
99lateral sprouting from an epithelium (GO:0060601)2.67698101
100neuron recognition (GO:0008038)2.66901959
101GPI anchor metabolic process (GO:0006505)2.66202052
102positive regulation of synapse assembly (GO:0051965)2.65789055
103deoxyribonucleoside monophosphate metabolic process (GO:0009162)2.65453842
104sympathetic nervous system development (GO:0048485)2.65176541
105cornea development in camera-type eye (GO:0061303)2.64382051
106response to redox state (GO:0051775)2.63588578
107protein import into peroxisome matrix (GO:0016558)2.63205625
108DNA double-strand break processing (GO:0000729)2.62398703
109nucleotide-excision repair, DNA gap filling (GO:0006297)2.62302184
110polyol transport (GO:0015791)2.62259454
111telomere maintenance via telomere lengthening (GO:0010833)2.61252360
112developmental pigmentation (GO:0048066)2.60629360
113regulation of somitogenesis (GO:0014807)2.58960455
114preassembly of GPI anchor in ER membrane (GO:0016254)2.58265070
115telomere maintenance via semi-conservative replication (GO:0032201)2.58043638
116gamma-aminobutyric acid signaling pathway (GO:0007214)2.57609959
117intestinal cholesterol absorption (GO:0030299)2.57592113
118regulation of prostaglandin secretion (GO:0032306)2.57397633
119DNA strand elongation involved in DNA replication (GO:0006271)2.57368108
120photoreceptor cell maintenance (GO:0045494)2.57023369
121nucleotide transmembrane transport (GO:1901679)2.56585854
122inner ear receptor stereocilium organization (GO:0060122)2.56573295
123protein K11-linked ubiquitination (GO:0070979)2.56400453
124L-fucose metabolic process (GO:0042354)2.56302110
125L-fucose catabolic process (GO:0042355)2.56302110
126fucose catabolic process (GO:0019317)2.56302110
127regulation of feeding behavior (GO:0060259)2.55713336
128nucleoside diphosphate phosphorylation (GO:0006165)2.54710415
129coenzyme catabolic process (GO:0009109)2.52930800
130deoxyribose phosphate biosynthetic process (GO:0046385)2.52758106
1312-deoxyribonucleotide biosynthetic process (GO:0009265)2.52758106
132mucosal immune response (GO:0002385)2.52592379
133negative regulation of neurotransmitter secretion (GO:0046929)2.52474056
134adult feeding behavior (GO:0008343)2.52254544
135positive regulation of protein kinase C signaling (GO:0090037)2.51411750
136positive regulation of developmental pigmentation (GO:0048087)2.50930351
137spinal cord association neuron differentiation (GO:0021527)2.50593388
138maintenance of fidelity involved in DNA-dependent DNA replication (GO:0045005)2.50368575
139amino acid import (GO:0043090)2.50346704
140replication fork processing (GO:0031297)2.49098921
141G-protein coupled glutamate receptor signaling pathway (GO:0007216)2.49058179
142otic vesicle formation (GO:0030916)2.48519409
143cell differentiation in spinal cord (GO:0021515)2.47706434
144forebrain morphogenesis (GO:0048853)2.47397946
145reflex (GO:0060004)2.47102104
146regulation of mitochondrial translation (GO:0070129)2.46697258
147startle response (GO:0001964)2.46467026
148nonmotile primary cilium assembly (GO:0035058)2.46262781
149L-methionine salvage (GO:0071267)2.45868285
150L-methionine biosynthetic process (GO:0071265)2.45868285
151amino acid salvage (GO:0043102)2.45868285
152cellular response to epinephrine stimulus (GO:0071872)2.45854287
153protein-DNA complex assembly (GO:0065004)2.45788196
154biotin metabolic process (GO:0006768)2.45139777
155protein-chromophore linkage (GO:0018298)2.45051760
156mitochondrial electron transport, NADH to ubiquinone (GO:0006120)2.44405386
157antibacterial humoral response (GO:0019731)2.44385443
158nucleosome assembly (GO:0006334)2.43912352
159methionine biosynthetic process (GO:0009086)2.42746438
160negative regulation of peptidyl-threonine phosphorylation (GO:0010801)2.42432541
161negative regulation of myoblast differentiation (GO:0045662)2.42308260
162DNA strand elongation (GO:0022616)2.42041854
163mitotic recombination (GO:0006312)2.40564098
164cilium movement (GO:0003341)2.40256834
165synapsis (GO:0007129)2.40124478
166water-soluble vitamin biosynthetic process (GO:0042364)2.39950093
167tRNA processing (GO:0008033)2.39914446
168positive regulation of mitochondrial fission (GO:0090141)2.39721723
169positive regulation of meiosis (GO:0045836)2.39531555
170axonemal dynein complex assembly (GO:0070286)2.39410387
171pseudouridine synthesis (GO:0001522)2.39322813
172response to epinephrine (GO:0071871)2.39015481
173reciprocal meiotic recombination (GO:0007131)2.38193426
174reciprocal DNA recombination (GO:0035825)2.38193426
175deoxyribonucleotide biosynthetic process (GO:0009263)2.37973662
176telomere maintenance via recombination (GO:0000722)2.36877804
177auditory receptor cell stereocilium organization (GO:0060088)2.36162433
178dendritic spine morphogenesis (GO:0060997)2.35614969
179cell proliferation in forebrain (GO:0021846)2.35098636
180positive regulation of uterine smooth muscle contraction (GO:0070474)2.34361130
181exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay 2.34304455
182positive regulation of meiotic cell cycle (GO:0051446)2.33377543
183nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291)2.33310873
184regulation of collateral sprouting (GO:0048670)2.32621138
185kidney morphogenesis (GO:0060993)2.32521017
186adenosine metabolic process (GO:0046085)2.31891241
187lymphoid progenitor cell differentiation (GO:0002320)2.28372964
188opioid receptor signaling pathway (GO:0038003)2.27318085
189regulation of synapse assembly (GO:0051963)2.26180246
190positive regulation of cellular amine metabolic process (GO:0033240)2.26167705
191regulation of platelet aggregation (GO:0090330)2.25468593
192regulation of catecholamine metabolic process (GO:0042069)2.25012968
193regulation of dopamine metabolic process (GO:0042053)2.25012968
194dopamine biosynthetic process (GO:0042416)2.24919816
195axonal fasciculation (GO:0007413)2.24418988
196head development (GO:0060322)2.24289146

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1EZH2_22144423_ChIP-Seq_EOC_Human4.15952898
2GBX2_23144817_ChIP-Seq_PC3_Human3.60425058
3HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse3.30107958
4BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse3.19861812
5JARID2_20064375_ChIP-Seq_MESCs_Mouse2.80694369
6EZH2_27304074_Chip-Seq_ESCs_Mouse2.65032733
7BMI1_23680149_ChIP-Seq_NPCS_Mouse2.58745084
8E2F4_17652178_ChIP-ChIP_JURKAT_Human2.55088254
9EED_16625203_ChIP-ChIP_MESCs_Mouse2.52988031
10ZFP57_27257070_Chip-Seq_ESCs_Mouse2.51788744
11SUZ12_18692474_ChIP-Seq_MESCs_Mouse2.51050813
12HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human2.47331774
13E2F7_22180533_ChIP-Seq_HELA_Human2.43338803
14VDR_22108803_ChIP-Seq_LS180_Human2.41588806
15CBX2_27304074_Chip-Seq_ESCs_Mouse2.40708173
16KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human2.39790651
17SUZ12_18555785_ChIP-Seq_MESCs_Mouse2.37059690
18SUZ12_16625203_ChIP-ChIP_MESCs_Mouse2.31999561
19GABP_17652178_ChIP-ChIP_JURKAT_Human2.29978805
20TAF15_26573619_Chip-Seq_HEK293_Human2.26389597
21CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human2.25484459
22SUZ12_18974828_ChIP-Seq_MESCs_Mouse2.19681883
23JARID2_20075857_ChIP-Seq_MESCs_Mouse2.19038357
24RNF2_18974828_ChIP-Seq_MESCs_Mouse2.18335091
25EZH2_18974828_ChIP-Seq_MESCs_Mouse2.18335091
26SUZ12_18692474_ChIP-Seq_MEFs_Mouse2.18079724
27ZNF274_21170338_ChIP-Seq_K562_Hela2.17848124
28GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse2.14454405
29TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse2.13315899
30MYCN_21190229_ChIP-Seq_SHEP-21N_Human2.10550797
31ELK1_19687146_ChIP-ChIP_HELA_Human2.03706783
32VDR_23849224_ChIP-Seq_CD4+_Human2.01100686
33EZH2_27294783_Chip-Seq_ESCs_Mouse2.00596485
34FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse11.5154640
35CHD1_19587682_ChIP-ChIP_MESCs_Mouse1.96425924
36SUZ12_27294783_Chip-Seq_ESCs_Mouse1.94653102
37PCGF2_27294783_Chip-Seq_ESCs_Mouse1.89387326
38RNF2_27304074_Chip-Seq_ESCs_Mouse1.87223193
39PHC1_16625203_ChIP-ChIP_MESCs_Mouse1.85060396
40RNF2_27304074_Chip-Seq_NSC_Mouse1.83085775
41POU3F2_20337985_ChIP-ChIP_501MEL_Human1.81403606
42MYC_18555785_ChIP-Seq_MESCs_Mouse1.78236414
43RNF2_16625203_ChIP-ChIP_MESCs_Mouse1.76547260
44EST1_17652178_ChIP-ChIP_JURKAT_Human1.76480161
45IGF1R_20145208_ChIP-Seq_DFB_Human1.76260006
46MTF2_20144788_ChIP-Seq_MESCs_Mouse1.76159301
47PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.75024919
48EGR1_23403033_ChIP-Seq_LIVER_Mouse1.74944330
49CREB1_15753290_ChIP-ChIP_HEK293T_Human1.74804573
50SUZ12_20075857_ChIP-Seq_MESCs_Mouse1.74666620
51FLI1_27457419_Chip-Seq_LIVER_Mouse1.70888908
52P300_19829295_ChIP-Seq_ESCs_Human1.70164455
53ETS1_20019798_ChIP-Seq_JURKAT_Human1.68485191
54CTBP1_25329375_ChIP-Seq_LNCAP_Human1.68302782
55SOX2_16153702_ChIP-ChIP_HESCs_Human1.68230927
56JARID1A_20064375_ChIP-Seq_MESCs_Mouse1.68213016
57SUZ12_27294783_Chip-Seq_NPCs_Mouse1.67209585
58AR_21572438_ChIP-Seq_LNCaP_Human1.66807938
59NOTCH1_17114293_ChIP-ChIP_T-ALL_Human1.65929136
60FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse1.65704301
61PCGF2_27294783_Chip-Seq_NPCs_Mouse1.65476450
62CTBP2_25329375_ChIP-Seq_LNCAP_Human1.64061432
63MYC_18940864_ChIP-ChIP_HL60_Human1.63706096
64PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse1.63626942
65E2F1_21310950_ChIP-Seq_MCF-7_Human1.58284053
66CDX2_19796622_ChIP-Seq_MESCs_Mouse1.58235719
67GLI1_17442700_ChIP-ChIP_MESCs_Mouse1.57458189
68TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse1.52950124
69FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human1.52710910
70NFE2_27457419_Chip-Seq_LIVER_Mouse1.52459171
71NANOG_18555785_Chip-Seq_ESCs_Mouse1.51500320
72EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse1.51107334
73FOXP3_21729870_ChIP-Seq_TREG_Human1.50786302
74SMAD3_21741376_ChIP-Seq_EPCs_Human1.49926115
75PIAS1_25552417_ChIP-Seq_VCAP_Human1.46942751
76SOX9_22984422_ChIP-ChIP_TESTIS_Rat1.46261845
77EZH2_27294783_Chip-Seq_NPCs_Mouse1.45213085
78POU5F1_16153702_ChIP-ChIP_HESCs_Human1.44291613
79HCFC1_20581084_ChIP-Seq_MESCs_Mouse1.43601488
80CHD7_19251738_ChIP-ChIP_MESCs_Mouse1.43375992
81FUS_26573619_Chip-Seq_HEK293_Human1.42991729
82SUZ12_18555785_Chip-Seq_ESCs_Mouse1.41050859
83ER_23166858_ChIP-Seq_MCF-7_Human1.40013251
84E2F1_18555785_Chip-Seq_ESCs_Mouse1.39064359
85P53_22387025_ChIP-Seq_ESCs_Mouse1.37470480
86CMYC_18555785_Chip-Seq_ESCs_Mouse1.36995388
87SRF_21415370_ChIP-Seq_HL-1_Mouse1.35747268
88EBF1_22473956_ChIP-Seq_LYMPHODE_Mouse1.35525998
89CEBPD_23245923_ChIP-Seq_MEFs_Mouse1.34217869
90STAT3_18555785_Chip-Seq_ESCs_Mouse1.33534043
91P300_18555785_Chip-Seq_ESCs_Mouse1.33322344
92OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.32496211
93SMAD4_21799915_ChIP-Seq_A2780_Human1.30857848
94REST_21632747_ChIP-Seq_MESCs_Mouse1.29767405
95MYBL2_22936984_ChIP-ChIP_MESCs_Mouse1.29529632
96SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.28663843
97RCOR1_19997604_ChIP-ChIP_NEURONS_Mouse1.28245123
98AR_21909140_ChIP-Seq_LNCAP_Human1.27174507
99PADI4_21655091_ChIP-ChIP_MCF-7_Human1.27075753
100UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human1.26989795
101NMYC_18555785_Chip-Seq_ESCs_Mouse1.26131929
102BP1_19119308_ChIP-ChIP_Hs578T_Human1.26012082
103SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.25983514
104RUNX1_27457419_Chip-Seq_LIVER_Mouse1.25072426
105TOP2B_26459242_ChIP-Seq_MCF-7_Human1.24598637
106DROSHA_22980978_ChIP-Seq_HELA_Human1.24090455
107EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human1.23551782
108CEBPB_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.23213751
109TAL1_26923725_Chip-Seq_HPCs_Mouse1.22683538
110ZFP42_18358816_ChIP-ChIP_MESCs_Mouse1.21186776
111OCT4_18555785_Chip-Seq_ESCs_Mouse1.19705168
112SOX2_18555785_Chip-Seq_ESCs_Mouse1.19142506
113TP53_22573176_ChIP-Seq_HFKS_Human1.19020927
114POU5F1_26923725_Chip-Seq_MESODERM_Mouse1.17856571
115TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.17856571
116NOTCH1_21737748_ChIP-Seq_TLL_Human1.17544123
117TP53_18474530_ChIP-ChIP_U2OS_Human1.17323439
118SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.17114160
119KLF4_18555785_Chip-Seq_ESCs_Mouse1.16865434
120MYC_19030024_ChIP-ChIP_MESCs_Mouse1.15683065
121TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.13645789
122MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse1.13322392
123ZFX_18555785_Chip-Seq_ESCs_Mouse1.13222780
124CNOT3_19339689_ChIP-ChIP_MESCs_Mouse1.13038013
125MYC_18358816_ChIP-ChIP_MESCs_Mouse1.12632667
126HOXB4_20404135_ChIP-ChIP_EML_Mouse1.12365094
127MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human1.11165965
128PU1_27457419_Chip-Seq_LIVER_Mouse1.10363865
129NANOG_16153702_ChIP-ChIP_HESCs_Human1.09857464
130GABP_19822575_ChIP-Seq_HepG2_Human1.09854778
131SMAD1_18555785_Chip-Seq_ESCs_Mouse1.09531080
132ESRRB_18555785_Chip-Seq_ESCs_Mouse1.08901470
133DCP1A_22483619_ChIP-Seq_HELA_Human1.08747850
134* RUNX2_22187159_ChIP-Seq_PCA_Human1.07838949
135GATA1_22025678_ChIP-Seq_K562_Human1.07533672
136KDM2B_26808549_Chip-Seq_REH_Human1.07247342
137CRX_20693478_ChIP-Seq_RETINA_Mouse1.05622766
138IKZF1_21737484_ChIP-ChIP_HCT116_Human1.05455802
139E2F1_18555785_ChIP-Seq_MESCs_Mouse1.05248455
140THAP11_20581084_ChIP-Seq_MESCs_Mouse1.05240866
141* IRF1_19129219_ChIP-ChIP_H3396_Human1.04981362
142NR3C1_21868756_ChIP-Seq_MCF10A_Human1.04685806
143CDX2_21402776_ChIP-Seq_INTESTINAL-VILLUS_Mouse1.04593333
144CTCF_18555785_Chip-Seq_ESCs_Mouse1.03747212
145NELFA_20434984_ChIP-Seq_ESCs_Mouse1.03565824
146STAT3_23295773_ChIP-Seq_U87_Human1.00997679
147SALL1_21062744_ChIP-ChIP_HESCs_Human1.00640221
148OCT4_21477851_ChIP-Seq_ESCs_Mouse1.00481380
149POU5F1_18358816_ChIP-ChIP_MESCs_Mouse0.99523915
150AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human0.99491110
151PRDM14_20953172_ChIP-Seq_ESCs_Human0.99154952
152EWS_26573619_Chip-Seq_HEK293_Human0.99071118
153TP53_16413492_ChIP-PET_HCT116_Human0.98533947
154PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse0.98402591
155ERG_20887958_ChIP-Seq_HPC-7_Mouse0.96351137
156YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse0.95208074
157NANOG_19829295_ChIP-Seq_ESCs_Human0.93088569
158SOX2_19829295_ChIP-Seq_ESCs_Human0.93088569
159FOXP2_21765815_ChIP-ChIP_NEURO2A_Mouse0.92052556
160KDM5B_21448134_ChIP-Seq_MESCs_Mouse0.91838240
161PPARD_23208498_ChIP-Seq_MDA-MB-231_Human0.91254589
162TTF2_22483619_ChIP-Seq_HELA_Human0.91194362
163HTT_18923047_ChIP-ChIP_STHdh_Human0.89432106
164* FOXA1_21572438_ChIP-Seq_LNCaP_Human0.89060402
165POU5F1_18555785_ChIP-Seq_MESCs_Mouse0.85871072
166CBP_20019798_ChIP-Seq_JUKART_Human0.84811647
167IRF4_20064451_ChIP-Seq_CD4+T_Mouse0.84811647
168ZFP322A_24550733_ChIP-Seq_MESCs_Mouse0.81037303
169AUTS2_25519132_ChIP-Seq_293T-REX_Human0.80558944
170SOX2_19030024_ChIP-ChIP_MESCs_Mouse0.79597929
171FOXA1_25329375_ChIP-Seq_VCAP_Human0.78501821
172FOXA1_27270436_Chip-Seq_PROSTATE_Human0.78501821

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0003136_yellow_coat_color4.06116701
2MP0002234_abnormal_pharynx_morphology3.84345173
3MP0002102_abnormal_ear_morphology3.50942920
4MP0002822_catalepsy3.35729516
5MP0003880_abnormal_central_pattern3.31817769
6MP0006292_abnormal_olfactory_placode3.19751417
7MP0000566_synostosis2.83736558
8MP0001188_hyperpigmentation2.79592461
9MP0004381_abnormal_hair_follicle2.76373326
10MP0010094_abnormal_chromosome_stability2.70009212
11MP0002009_preneoplasia2.67911982
12MP0004742_abnormal_vestibular_system2.63459803
13MP0005409_darkened_coat_color2.62689457
14MP0005423_abnormal_somatic_nervous2.59022922
15MP0001486_abnormal_startle_reflex2.39981955
16MP0008057_abnormal_DNA_replication2.38814371
17MP0005171_absent_coat_pigmentation2.36628666
18MP0008961_abnormal_basal_metabolism2.28545347
19MP0002160_abnormal_reproductive_system2.23974548
20MP0002837_dystrophic_cardiac_calcinosis2.20401440
21MP0008058_abnormal_DNA_repair2.11894038
22MP0004147_increased_porphyrin_level1.96533318
23MP0000920_abnormal_myelination1.95173792
24MP0003693_abnormal_embryo_hatching1.94730805
25MP0001986_abnormal_taste_sensitivity1.89643351
26MP0002272_abnormal_nervous_system1.88451682
27MP0004142_abnormal_muscle_tone1.83673100
28MP0003938_abnormal_ear_development1.83618866
29MP0001905_abnormal_dopamine_level1.75403443
30MP0005645_abnormal_hypothalamus_physiol1.74159249
31MP0009697_abnormal_copulation1.73866034
32MP0009745_abnormal_behavioral_response1.72223115
33MP0000026_abnormal_inner_ear1.71918708
34MP0001485_abnormal_pinna_reflex1.71846866
35MP0005551_abnormal_eye_electrophysiolog1.71651562
36MP0003868_abnormal_feces_composition1.71323508
37MP0005379_endocrine/exocrine_gland_phen1.63330465
38MP0003718_maternal_effect1.58799819
39MP0002277_abnormal_respiratory_mucosa1.58190358
40MP0005646_abnormal_pituitary_gland1.58148896
41MP0006276_abnormal_autonomic_nervous1.57451728
42MP0008007_abnormal_cellular_replicative1.57445584
43MP0002396_abnormal_hematopoietic_system1.56250248
44MP0006072_abnormal_retinal_apoptosis1.54732385
45MP0000778_abnormal_nervous_system1.53504719
46MP0002064_seizures1.52265365
47MP0001963_abnormal_hearing_physiology1.51583059
48MP0004270_analgesia1.51151620
49MP0003195_calcinosis1.50772584
50MP0001764_abnormal_homeostasis1.48373141
51MP0002638_abnormal_pupillary_reflex1.47809317
52MP0002249_abnormal_larynx_morphology1.47638428
53MP0002572_abnormal_emotion/affect_behav1.47460141
54MP0001968_abnormal_touch/_nociception1.46960923
55MP0009046_muscle_twitch1.46938353
56MP0000631_abnormal_neuroendocrine_gland1.46381943
57MP0003635_abnormal_synaptic_transmissio1.46342080
58MP0001666_abnormal_nutrient_absorption1.45710718
59MP0001529_abnormal_vocalization1.44322869
60MP0008260_abnormal_autophagy1.40573526
61MP0002735_abnormal_chemical_nociception1.37928431
62MP0001440_abnormal_grooming_behavior1.36542705
63MP0004957_abnormal_blastocyst_morpholog1.36526350
64MP0005397_hematopoietic_system_phenotyp1.36497081
65MP0001545_abnormal_hematopoietic_system1.36497081
66MP0002067_abnormal_sensory_capabilities1.33763141
67MP0005410_abnormal_fertilization1.33544794
68MP0005220_abnormal_exocrine_pancreas1.33314328
69MP0008932_abnormal_embryonic_tissue1.33107841
70MP0005085_abnormal_gallbladder_physiolo1.33031749
71MP0010386_abnormal_urinary_bladder1.32519395
72MP0000049_abnormal_middle_ear1.32375468
73MP0004215_abnormal_myocardial_fiber1.32353989
74MP0006036_abnormal_mitochondrial_physio1.30726874
75MP0001346_abnormal_lacrimal_gland1.30106481
76MP0003950_abnormal_plasma_membrane1.29531321
77MP0009379_abnormal_foot_pigmentation1.29511337
78MP0002752_abnormal_somatic_nervous1.28124316
79MP0004484_altered_response_of1.27898089
80MP0002557_abnormal_social/conspecific_i1.26865318
81MP0002734_abnormal_mechanical_nocicepti1.25106238
82MP0003077_abnormal_cell_cycle1.25010250
83MP0005389_reproductive_system_phenotype1.23038258
84MP0009250_abnormal_appendicular_skeleto1.20849447
85MP0000749_muscle_degeneration1.20800921
86MP0005253_abnormal_eye_physiology1.20604859
87MP0000383_abnormal_hair_follicle1.20175149
88MP0002938_white_spotting1.19794287
89MP0008995_early_reproductive_senescence1.19327824
90MP0003786_premature_aging1.16804247
91MP0004134_abnormal_chest_morphology1.16611667
92MP0002184_abnormal_innervation1.15060699
93MP0004859_abnormal_synaptic_plasticity1.14317860
94MP0002063_abnormal_learning/memory/cond1.13297148
95MP0000462_abnormal_digestive_system1.13280090
96MP0003698_abnormal_male_reproductive1.12983513
97MP0008872_abnormal_physiological_respon1.12720088
98MP0001145_abnormal_male_reproductive1.12558886
99MP0004133_heterotaxia1.12285784
100MP0001501_abnormal_sleep_pattern1.09864157
101MP0002138_abnormal_hepatobiliary_system1.09835119
102MP0000762_abnormal_tongue_morphology1.06803608
103MP0001929_abnormal_gametogenesis1.06477888
104MP0003656_abnormal_erythrocyte_physiolo1.05870511
105MP0001984_abnormal_olfaction1.05819067
106MP0005365_abnormal_bile_salt1.05157082
107MP0002876_abnormal_thyroid_physiology1.04728275
108MP0002882_abnormal_neuron_morphology1.04448743
109MP0001970_abnormal_pain_threshold1.04437293
110MP0003937_abnormal_limbs/digits/tail_de1.04385682
111MP0001661_extended_life_span1.02277765
112MP0000681_abnormal_thyroid_gland1.01708886
113MP0005451_abnormal_body_composition1.01368871
114MP0002736_abnormal_nociception_after1.01328988
115MP0004808_abnormal_hematopoietic_stem0.99797851
116MP0000653_abnormal_sex_gland0.99611287
117MP0001502_abnormal_circadian_rhythm0.99324567
118MP0004145_abnormal_muscle_electrophysio0.98681737
119MP0003011_delayed_dark_adaptation0.98603517
120MP0004885_abnormal_endolymph0.98208450
121MP0002233_abnormal_nose_morphology0.97065198
122MP0003787_abnormal_imprinting0.96476774
123MP0002210_abnormal_sex_determination0.95688843
124MP0002751_abnormal_autonomic_nervous0.94779942
125MP0005187_abnormal_penis_morphology0.94210210
126MP0003283_abnormal_digestive_organ0.93777022
127MP0003315_abnormal_perineum_morphology0.93688767
128MP0003111_abnormal_nucleus_morphology0.93069841
129MP0005367_renal/urinary_system_phenotyp0.92617894
130MP0000516_abnormal_urinary_system0.92617894
131MP0005195_abnormal_posterior_eye0.91883210
132MP0008789_abnormal_olfactory_epithelium0.91630915
133MP0005332_abnormal_amino_acid0.91017221
134MP0001664_abnormal_digestion0.90263490
135MP0000015_abnormal_ear_pigmentation0.89304768
136MP0003690_abnormal_glial_cell0.89249748
137MP0005377_hearing/vestibular/ear_phenot0.88959254
138MP0003878_abnormal_ear_physiology0.88959254
139MP0002229_neurodegeneration0.88807929
140MP0003959_abnormal_lean_body0.88752983
141MP0000613_abnormal_salivary_gland0.88459191
142MP0003119_abnormal_digestive_system0.88291454
143MP0005084_abnormal_gallbladder_morpholo0.87325610
144MP0001293_anophthalmia0.87155327
145MP0000372_irregular_coat_pigmentation0.87057145
146MP0002733_abnormal_thermal_nociception0.86276986
147MP0002098_abnormal_vibrissa_morphology0.84510720
148MP0003646_muscle_fatigue0.84177891
149MP0002163_abnormal_gland_morphology0.82333254
150MP0006035_abnormal_mitochondrial_morpho0.81466671
151MP0003724_increased_susceptibility_to0.78263640
152MP0000647_abnormal_sebaceous_gland0.78239162
153MP0002066_abnormal_motor_capabilities/c0.78165733
154MP0005174_abnormal_tail_pigmentation0.78147523
155MP0003385_abnormal_body_wall0.77630352
156MP0002177_abnormal_outer_ear0.76402296
157MP0005083_abnormal_biliary_tract0.76188135
158MP0010678_abnormal_skin_adnexa0.74707542
159MP0002653_abnormal_ependyma_morphology0.74267319
160MP0003186_abnormal_redox_activity0.73087125
161MP0001119_abnormal_female_reproductive0.72809768
162MP0002090_abnormal_vision0.72512822
163MP0002932_abnormal_joint_morphology0.70073670
164MP0003252_abnormal_bile_duct0.68530849
165MP0005266_abnormal_metabolism0.68349671
166MP0002095_abnormal_skin_pigmentation0.67473901
167MP0002084_abnormal_developmental_patter0.66269526

Predicted human phenotypes

RankGene SetZ-score
1Parakeratosis (HP:0001036)4.26788781
2Dynein arm defect of respiratory motile cilia (HP:0012255)4.13708462
3Absent/shortened dynein arms (HP:0200106)4.13708462
4Septo-optic dysplasia (HP:0100842)4.08843620
5Abnormal ciliary motility (HP:0012262)4.03121194
6Respiratory insufficiency due to defective ciliary clearance (HP:0200073)3.94901263
7Lipid accumulation in hepatocytes (HP:0006561)3.75280186
8Abnormal rod and cone electroretinograms (HP:0008323)3.63846672
9Increased hepatocellular lipid droplets (HP:0006565)3.58408901
10Abnormal respiratory motile cilium physiology (HP:0012261)3.52157126
11White forelock (HP:0002211)3.42502270
12Abnormal respiratory motile cilium morphology (HP:0005938)3.37884834
13Abnormal respiratory epithelium morphology (HP:0012253)3.37884834
14Patchy hypopigmentation of hair (HP:0011365)3.35080077
15Cerebellar dysplasia (HP:0007033)3.22845181
16Aplasia cutis congenita (HP:0001057)3.19727561
17Decreased central vision (HP:0007663)3.14563213
18Type II lissencephaly (HP:0007260)3.12352023
19Absent septum pellucidum (HP:0001331)3.07773237
20Hypoplasia of the pons (HP:0012110)3.07617604
21Hepatocellular necrosis (HP:0001404)3.05503776
22Duplicated collecting system (HP:0000081)3.04032696
23Oral leukoplakia (HP:0002745)3.01826457
24Degeneration of the lateral corticospinal tracts (HP:0002314)2.96147317
25Atrophy/Degeneration involving the corticospinal tracts (HP:0007372)2.96147317
26Hepatic necrosis (HP:0002605)2.95485105
27Mitochondrial inheritance (HP:0001427)2.90748899
28Cerebral edema (HP:0002181)2.87780043
29Congenital nonbullous ichthyosiform erythroderma (HP:0007479)2.84386649
30Abnormality of macular pigmentation (HP:0008002)2.79925116
31Abnormality of the renal collecting system (HP:0004742)2.79374539
32Stenosis of the external auditory canal (HP:0000402)2.74188707
33Abnormality of the septum pellucidum (HP:0007375)2.74175442
34Abnormality of the pons (HP:0007361)2.70932410
35Abnormality of the axillary hair (HP:0100134)2.68145455
36Abnormality of secondary sexual hair (HP:0009888)2.68145455
37Optic nerve hypoplasia (HP:0000609)2.66354304
38Type I transferrin isoform profile (HP:0003642)2.66282437
39Central scotoma (HP:0000603)2.65782874
40Nasolacrimal duct obstruction (HP:0000579)2.65560840
41Hyperglycinemia (HP:0002154)2.63857483
42Pancreatic cysts (HP:0001737)2.63747665
43Focal motor seizures (HP:0011153)2.60673859
44Increased intramyocellular lipid droplets (HP:0012240)2.59058851
45Upper limb muscle weakness (HP:0003484)2.58586553
46Microvesicular hepatic steatosis (HP:0001414)2.55365049
47Calf muscle hypertrophy (HP:0008981)2.55171280
48Short 1st metacarpal (HP:0010034)2.53421260
49Aplasia/Hypoplasia of the 1st metacarpal (HP:0010026)2.53421260
50Increased CSF lactate (HP:0002490)2.52469884
51Duplication of thumb phalanx (HP:0009942)2.52023554
52Lactic acidosis (HP:0003128)2.50559783
53Short phalanx of the thumb (HP:0009660)2.48234364
54Congenital stationary night blindness (HP:0007642)2.47738188
55Ketosis (HP:0001946)2.47468234
56Colon cancer (HP:0003003)2.46909319
57Conical tooth (HP:0000698)2.42998174
58Chromosomal breakage induced by crosslinking agents (HP:0003221)2.41520848
59Retinal dysplasia (HP:0007973)2.41114791
60Increased serum lactate (HP:0002151)2.38339035
61Congenital sensorineural hearing impairment (HP:0008527)2.37319807
62Attenuation of retinal blood vessels (HP:0007843)2.36884706
63Abnormality of the 1st metacarpal (HP:0010009)2.34285777
64Increased corneal curvature (HP:0100692)2.31971642
65Keratoconus (HP:0000563)2.31971642
66Muscle hypertrophy of the lower extremities (HP:0008968)2.31969233
67Dyschromatopsia (HP:0007641)2.31909446
68Increased muscle lipid content (HP:0009058)2.31248177
69Abnormal protein glycosylation (HP:0012346)2.28330379
70Abnormal glycosylation (HP:0012345)2.28330379
71Abnormal isoelectric focusing of serum transferrin (HP:0003160)2.28330379
72Abnormal protein N-linked glycosylation (HP:0012347)2.28330379
73Glycosuria (HP:0003076)2.27962651
74Abnormality of urine glucose concentration (HP:0011016)2.27962651
75Severe visual impairment (HP:0001141)2.26977398
76Abnormality of the lacrimal duct (HP:0011481)2.25703551
77Cupped ear (HP:0000378)2.23970661
78Tubulointerstitial nephritis (HP:0001970)2.23403016
79Febrile seizures (HP:0002373)2.23356116
80Medial flaring of the eyebrow (HP:0010747)2.22939830
81Thyroid-stimulating hormone excess (HP:0002925)2.21860472
82Overfolded helix (HP:0000396)2.21397855
83Acute encephalopathy (HP:0006846)2.21030236
84Atelectasis (HP:0100750)2.20982985
85Abnormal sex determination (HP:0012244)2.20311740
86Sex reversal (HP:0012245)2.20311740
87Renal cortical cysts (HP:0000803)2.19367038
88Alacrima (HP:0000522)2.16913516
89Hyperglycinuria (HP:0003108)2.15576467
90Chorioretinal atrophy (HP:0000533)2.15188900
91Morphological abnormality of the middle ear (HP:0008609)2.14472330
92Bile duct proliferation (HP:0001408)2.14405485
93Abnormal biliary tract physiology (HP:0012439)2.14405485
94Aplasia/Hypoplasia of the tibia (HP:0005772)2.13572465
95Aplasia/Hypoplasia of the optic nerve (HP:0008058)2.10217958
96Rhinitis (HP:0012384)2.10188004
97Short tibia (HP:0005736)2.09870663
98Neurofibrillary tangles (HP:0002185)2.09333042
99Metabolic alkalosis (HP:0200114)2.07614252
100Abnormality of the nasolacrimal system (HP:0000614)2.06890087
101Pendular nystagmus (HP:0012043)2.05486816
102Aplasia/Hypoplasia of the lens (HP:0008063)2.05286364
103Partial duplication of thumb phalanx (HP:0009944)2.04887495
104Prolonged neonatal jaundice (HP:0006579)2.02198432
105Osteomalacia (HP:0002749)2.01547288
106Decreased electroretinogram (ERG) amplitude (HP:0000654)2.00947303
107True hermaphroditism (HP:0010459)2.00913393
108Lethargy (HP:0001254)1.99943883
109Decreased lacrimation (HP:0000633)1.99838546
110Brushfield spots (HP:0001088)1.99773246
111Gait imbalance (HP:0002141)1.98736743
112Abnormality of the renal medulla (HP:0100957)1.97253352
113Renal agenesis (HP:0000104)1.96816714
114Aplasia involving bones of the extremities (HP:0009825)1.95708820
115Aplasia involving bones of the upper limbs (HP:0009823)1.95708820
116Aplasia of the phalanges of the hand (HP:0009802)1.95708820
117Absent rod-and cone-mediated responses on ERG (HP:0007688)1.95216165
118Abnormality of incisor morphology (HP:0011063)1.94910686
119Abnormality of glycine metabolism (HP:0010895)1.94468228
120Abnormality of serine family amino acid metabolism (HP:0010894)1.94468228
121Amelogenesis imperfecta (HP:0000705)1.93753345
122Mixed hearing impairment (HP:0000410)1.93524462
123Aplasia/Hypoplasia of the phalanges of the thumb (HP:0009658)1.93211088
124Peripheral hypomyelination (HP:0007182)1.92670169
125Hypomagnesemia (HP:0002917)1.91834926
126Reduced antithrombin III activity (HP:0001976)1.91034321
127Nephronophthisis (HP:0000090)1.89678487
128Nephrogenic diabetes insipidus (HP:0009806)1.89391996
129Degeneration of anterior horn cells (HP:0002398)1.89224043
130Abnormality of the anterior horn cell (HP:0006802)1.89224043
131Abnormality of the renal cortex (HP:0011035)1.88744805
132Aplasia/Hypoplasia of the uvula (HP:0010293)1.88404357
133Birth length less than 3rd percentile (HP:0003561)1.88382213
134Abnormal biliary tract morphology (HP:0012440)1.88270310
135Dicarboxylic aciduria (HP:0003215)1.87799647
136Abnormality of dicarboxylic acid metabolism (HP:0010995)1.87799647
137Chromsome breakage (HP:0040012)1.87456961
138Anomalous pulmonary venous return (HP:0010772)1.87357388
139Hypophosphatemic rickets (HP:0004912)1.87293690
140Respiratory failure (HP:0002878)1.87130286
141Acute necrotizing encephalopathy (HP:0006965)1.86892592
142Abnormality of fatty-acid metabolism (HP:0004359)1.86841136
143Acute lymphatic leukemia (HP:0006721)1.84686867
144Congenital primary aphakia (HP:0007707)1.84440767
145Abnormality of cochlea (HP:0000375)1.84294406
146Male pseudohermaphroditism (HP:0000037)1.84104865
147Abnormality of serum amino acid levels (HP:0003112)1.83368518
148Abolished electroretinogram (ERG) (HP:0000550)1.83227853
149Genital tract atresia (HP:0001827)1.81611138
150CNS demyelination (HP:0007305)1.80424036
151Hypothermia (HP:0002045)1.80299768
152Popliteal pterygium (HP:0009756)1.80257750
153Respiratory difficulties (HP:0002880)1.80015617
154Progressive macrocephaly (HP:0004481)1.79510401
155Abnormally folded helix (HP:0008544)1.78994551
1563-Methylglutaconic aciduria (HP:0003535)1.78839680
157Vaginal atresia (HP:0000148)1.78566630
158Hypoplasia of the iris (HP:0007676)1.77721887
159Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688)1.77170704
160Bony spicule pigmentary retinopathy (HP:0007737)1.76902553
161Abnormality of alanine metabolism (HP:0010916)1.76045766
162Hyperalaninemia (HP:0003348)1.76045766
163Abnormality of pyruvate family amino acid metabolism (HP:0010915)1.76045766
164Chin dimple (HP:0010751)1.75719236
165Recurrent corneal erosions (HP:0000495)1.75523067
166Absent eyebrow (HP:0002223)1.75258816
167Preaxial hand polydactyly (HP:0001177)1.74953565
168Abnormality of long-chain fatty-acid metabolism (HP:0010964)1.74843862
169Synostosis involving the elbow (HP:0003938)1.74577617
170Humeroradial synostosis (HP:0003041)1.74577617
171Abnormality of the corticospinal tract (HP:0002492)1.74359196
172Nonprogressive disorder (HP:0003680)1.74335242
173Optic disc pallor (HP:0000543)1.73321940
174Pancreatic fibrosis (HP:0100732)1.73079262
175Congenital ichthyosiform erythroderma (HP:0007431)1.72072331
176Corneal dystrophy (HP:0001131)1.71796632
177Abnormal mitochondria in muscle tissue (HP:0008316)1.71215220
178Renal Fanconi syndrome (HP:0001994)1.70955496
179Abnormality of the pulmonary veins (HP:0011718)1.70815883
180Anophthalmia (HP:0000528)1.70522361
181Sloping forehead (HP:0000340)1.70004595

Predicted kinase interactions (KEA)

RankGene SetZ-score
1BCKDK7.28613637
2CASK4.66079031
3BLK3.88843145
4EIF2AK33.82572478
5STK163.57541602
6TNIK3.46689570
7VRK13.05614921
8FRK3.02054885
9MAP3K42.97181965
10STK392.48670627
11PKN12.21293755
12BUB12.10804642
13MKNK22.06945191
14OXSR12.06270836
15MAP2K41.92480098
16ADRBK21.86723024
17INSRR1.84596739
18GRK11.83731252
19MUSK1.83355509
20NEK61.72997085
21SCYL21.59858598
22PBK1.57130355
23IRAK11.56823022
24BMPR1B1.56535532
25NTRK31.53346153
26MAP4K21.48633412
27PRKD31.44176690
28MAPK131.39398589
29PRPF4B1.38183887
30IRAK21.37447396
31PNCK1.37368495
32STK38L1.36602635
33CCNB11.35422856
34GRK71.32844535
35MAPK151.30687809
36MKNK11.29620549
37TAF11.29363304
38BCR1.26020018
39FGR1.22860788
40CDK31.22555099
41MARK11.21724245
42ERBB31.21453238
43CDC71.20952597
44NEK11.18316204
45EIF2AK21.17815969
46EPHA41.15936001
47IRAK41.13370255
48TXK1.12778398
49CLK11.12342435
50FLT31.12147311
51NTRK21.09217278
52YES11.08642483
53MAP2K71.08577382
54MAP3K141.08390429
55EPHB11.06138825
56VRK21.05081617
57BMPR21.03511942
58DYRK21.03236487
59MAPKAPK51.01150655
60UHMK11.01020191
61WNK40.99569690
62FES0.98986818
63MARK20.98032541
64AURKA0.97852890
65PRKCE0.94490856
66CDK80.92891633
67CAMK2B0.92359342
68CDK190.91715458
69NUAK10.91629270
70BRSK20.91386220
71DAPK30.91109972
72MAP3K130.89870242
73SIK30.89788895
74NME10.89580720
75ATR0.89228835
76RPS6KA40.89132548
77CHEK20.88791863
78ACVR1B0.87009109
79CSNK1A1L0.82363940
80MAP3K120.81347402
81SRPK10.81082893
82MST40.80131139
83PLK10.80091832
84CAMK2A0.79282095
85NME20.78956292
86PIM20.78941818
87CSNK1G30.74597174
88DYRK1A0.72926753
89PIK3CA0.72361192
90ROCK20.71914278
91PLK40.69515488
92IRAK30.68036172
93NEK90.67714907
94CAMK2D0.67363638
95AKT30.66391584
96CSNK1G10.65252538
97SIK20.65069827
98PIM10.65043834
99NLK0.64985773
100TNK20.64654392
101CAMK10.64403288
102PIK3CG0.64213974
103WNK10.62666885
104PLK30.62090074
105EPHB20.61160324
106PRKG10.60906405
107PRKCQ0.58872769
108NEK20.58385835
109PRKCI0.57299857
110EPHA30.56830187
111PRKD20.56230346
112CAMKK20.55791927
113EIF2AK10.55431607
114AURKB0.53789992
115ADRBK10.53476190
116ZAK0.52510171
117CAMK1G0.52398228
118CAMK40.52282448
119CSNK1G20.52056967
120TLK10.50359431
121ABL20.50131548
122RPS6KA50.47458123
123PRKACA0.46906753
124CAMK2G0.45543038
125TEC0.45184875
126MAP2K20.45036855
127LYN0.43872171
128SGK2230.43840275
129SGK4940.43840275
130WNK30.43241696
131BRD40.43008901
132FYN0.42797993
133STK40.41932667
134FER0.41890931
135PRKAA20.41329899
136OBSCN0.41229148
137CDK50.41011697
138LATS10.40712113
139ATM0.37862883
140TIE10.36696240
141AKT20.36535227
142RPS6KB10.36407467
143GRK50.36102930
144TTK0.35896203
145KDR0.35489885
146CDC42BPA0.35111403
147PKN20.34435751
148PRKCG0.33734998
149LCK0.32787462
150PAK60.31628394
151PAK30.31074054
152PHKG20.30686322
153MST1R0.29848674
154MAP2K60.29091983
155MAP3K50.28293878
156MAP3K110.28259778
157ILK0.26101858
158LMTK20.25868919
159MAP2K30.25193161
160WEE10.24020133
161TAOK30.22291345
162PRKAA10.20870058
163CAMK1D0.20504297
164CSNK2A10.18981937

Predicted pathways (KEGG)

RankGene SetZ-score
1Systemic lupus erythematosus_Homo sapiens_hsa053224.28359552
2Sulfur relay system_Homo sapiens_hsa041223.28485522
3Alcoholism_Homo sapiens_hsa050343.17416316
4Nicotine addiction_Homo sapiens_hsa050332.97931706
5Phototransduction_Homo sapiens_hsa047442.88469804
6Propanoate metabolism_Homo sapiens_hsa006402.77695907
7Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005632.55402676
8Neuroactive ligand-receptor interaction_Homo sapiens_hsa040802.44758225
9Ether lipid metabolism_Homo sapiens_hsa005652.37491445
10Valine, leucine and isoleucine degradation_Homo sapiens_hsa002802.35729461
11Homologous recombination_Homo sapiens_hsa034402.34675789
12DNA replication_Homo sapiens_hsa030302.28196262
13Mismatch repair_Homo sapiens_hsa034302.26481349
14Taurine and hypotaurine metabolism_Homo sapiens_hsa004302.20552143
15Terpenoid backbone biosynthesis_Homo sapiens_hsa009002.17400653
16Oxidative phosphorylation_Homo sapiens_hsa001902.09121370
17Fatty acid elongation_Homo sapiens_hsa000622.02456443
18Nucleotide excision repair_Homo sapiens_hsa034202.02194162
19Sphingolipid metabolism_Homo sapiens_hsa006001.98510054
20Serotonergic synapse_Homo sapiens_hsa047261.95317624
21Base excision repair_Homo sapiens_hsa034101.85058459
22Taste transduction_Homo sapiens_hsa047421.84766072
23Retrograde endocannabinoid signaling_Homo sapiens_hsa047231.83609074
24Autoimmune thyroid disease_Homo sapiens_hsa053201.83482174
25Cell adhesion molecules (CAMs)_Homo sapiens_hsa045141.78904957
26Morphine addiction_Homo sapiens_hsa050321.78529092
27Synthesis and degradation of ketone bodies_Homo sapiens_hsa000721.78243991
28Glutamatergic synapse_Homo sapiens_hsa047241.76718524
29Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006031.75974817
30Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006011.74651218
31Axon guidance_Homo sapiens_hsa043601.71718010
32Protein export_Homo sapiens_hsa030601.69582101
33Steroid biosynthesis_Homo sapiens_hsa001001.62993960
34GABAergic synapse_Homo sapiens_hsa047271.59813785
35Fat digestion and absorption_Homo sapiens_hsa049751.59321780
36Pyrimidine metabolism_Homo sapiens_hsa002401.58417455
37Butanoate metabolism_Homo sapiens_hsa006501.54745009
38Linoleic acid metabolism_Homo sapiens_hsa005911.53102043
39Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030081.50769247
40Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006301.46781400
41Arachidonic acid metabolism_Homo sapiens_hsa005901.44258469
42Graft-versus-host disease_Homo sapiens_hsa053321.41310231
43RNA polymerase_Homo sapiens_hsa030201.37028758
44Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005121.36838458
45Alzheimers disease_Homo sapiens_hsa050101.35115609
46One carbon pool by folate_Homo sapiens_hsa006701.32914491
47Glycine, serine and threonine metabolism_Homo sapiens_hsa002601.32739591
48alpha-Linolenic acid metabolism_Homo sapiens_hsa005921.26295445
49Asthma_Homo sapiens_hsa053101.24017632
50Parkinsons disease_Homo sapiens_hsa050121.23688842
51Fatty acid metabolism_Homo sapiens_hsa012121.23305418
52Purine metabolism_Homo sapiens_hsa002301.23137583
53Tryptophan metabolism_Homo sapiens_hsa003801.21565204
54Selenocompound metabolism_Homo sapiens_hsa004501.16778861
55Allograft rejection_Homo sapiens_hsa053301.16134250
56Peroxisome_Homo sapiens_hsa041461.15997131
57Fatty acid degradation_Homo sapiens_hsa000711.15993996
58Calcium signaling pathway_Homo sapiens_hsa040201.14943450
59N-Glycan biosynthesis_Homo sapiens_hsa005101.14279781
60Circadian entrainment_Homo sapiens_hsa047131.10701250
61Rheumatoid arthritis_Homo sapiens_hsa053231.08292245
62Cytokine-cytokine receptor interaction_Homo sapiens_hsa040601.06285726
63Salivary secretion_Homo sapiens_hsa049701.04990442
64Folate biosynthesis_Homo sapiens_hsa007901.04443547
65Collecting duct acid secretion_Homo sapiens_hsa049661.03332397
66Cardiac muscle contraction_Homo sapiens_hsa042601.02940423
67Cysteine and methionine metabolism_Homo sapiens_hsa002701.02500918
68Cell cycle_Homo sapiens_hsa041101.01783258
69Renin-angiotensin system_Homo sapiens_hsa046141.00841619
70Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009700.99944019
71Glutathione metabolism_Homo sapiens_hsa004800.99012148
72Long-term depression_Homo sapiens_hsa047300.97257606
73Huntingtons disease_Homo sapiens_hsa050160.96600150
74Fanconi anemia pathway_Homo sapiens_hsa034600.96385047
75Inflammatory bowel disease (IBD)_Homo sapiens_hsa053210.94333580
76Nitrogen metabolism_Homo sapiens_hsa009100.89012681
77Pyruvate metabolism_Homo sapiens_hsa006200.86260675
78RNA degradation_Homo sapiens_hsa030180.85916202
79SNARE interactions in vesicular transport_Homo sapiens_hsa041300.85832072
80Caffeine metabolism_Homo sapiens_hsa002320.85423753
81RNA transport_Homo sapiens_hsa030130.84809234
82Metabolic pathways_Homo sapiens_hsa011000.84407263
83Hematopoietic cell lineage_Homo sapiens_hsa046400.84186198
84Ras signaling pathway_Homo sapiens_hsa040140.83107858
85Steroid hormone biosynthesis_Homo sapiens_hsa001400.82820080
86Vascular smooth muscle contraction_Homo sapiens_hsa042700.82101817
87Cocaine addiction_Homo sapiens_hsa050300.81667529
88Ovarian steroidogenesis_Homo sapiens_hsa049130.80353458
89Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.80156911
90Pentose and glucuronate interconversions_Homo sapiens_hsa000400.79786175
91Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.79273025
92Viral carcinogenesis_Homo sapiens_hsa052030.77855017
93Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001300.76275414
94Retinol metabolism_Homo sapiens_hsa008300.75168761
95Cholinergic synapse_Homo sapiens_hsa047250.74841990
96Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049320.74556356
97beta-Alanine metabolism_Homo sapiens_hsa004100.73848453
98Transcriptional misregulation in cancer_Homo sapiens_hsa052020.72942017
99Regulation of autophagy_Homo sapiens_hsa041400.72184750
100Primary immunodeficiency_Homo sapiens_hsa053400.72083540
101Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.71568592
102Histidine metabolism_Homo sapiens_hsa003400.71363613
103Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.70837093
104Glycerolipid metabolism_Homo sapiens_hsa005610.69822908
105Starch and sucrose metabolism_Homo sapiens_hsa005000.68755274
106Renin secretion_Homo sapiens_hsa049240.68478401
107Spliceosome_Homo sapiens_hsa030400.67187328
108Non-homologous end-joining_Homo sapiens_hsa034500.66415980
109Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.64991543
110Insulin secretion_Homo sapiens_hsa049110.64850884
111Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054120.64808360
112cAMP signaling pathway_Homo sapiens_hsa040240.64553141
113Olfactory transduction_Homo sapiens_hsa047400.64246767
1142-Oxocarboxylic acid metabolism_Homo sapiens_hsa012100.63885247
115Pancreatic secretion_Homo sapiens_hsa049720.63098111
116Gastric acid secretion_Homo sapiens_hsa049710.62505460
117Wnt signaling pathway_Homo sapiens_hsa043100.62149080
118Oxytocin signaling pathway_Homo sapiens_hsa049210.62132181
119Maturity onset diabetes of the young_Homo sapiens_hsa049500.61930022
120Malaria_Homo sapiens_hsa051440.60757146
121Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.60263266
122Fatty acid biosynthesis_Homo sapiens_hsa000610.59812171
123Oocyte meiosis_Homo sapiens_hsa041140.59756263
124Protein digestion and absorption_Homo sapiens_hsa049740.59168575
125Amphetamine addiction_Homo sapiens_hsa050310.58360536
126Dopaminergic synapse_Homo sapiens_hsa047280.58061474
127p53 signaling pathway_Homo sapiens_hsa041150.57602365
128Arginine and proline metabolism_Homo sapiens_hsa003300.56389503
129African trypanosomiasis_Homo sapiens_hsa051430.55503723
130Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.55483909
131Cytosolic DNA-sensing pathway_Homo sapiens_hsa046230.54773903
132Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.54558884
133Intestinal immune network for IgA production_Homo sapiens_hsa046720.53466048
134Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.53197613
135Melanoma_Homo sapiens_hsa052180.53171969
136Phagosome_Homo sapiens_hsa041450.51374724
137Carbon metabolism_Homo sapiens_hsa012000.50853891
138Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.50745342
139Mineral absorption_Homo sapiens_hsa049780.50409166
140Sulfur metabolism_Homo sapiens_hsa009200.49420608
141Other glycan degradation_Homo sapiens_hsa005110.49292980
142Proteasome_Homo sapiens_hsa030500.49289662
143Drug metabolism - cytochrome P450_Homo sapiens_hsa009820.47753897
144Ascorbate and aldarate metabolism_Homo sapiens_hsa000530.47277891
145Primary bile acid biosynthesis_Homo sapiens_hsa001200.47108696
146Ribosome_Homo sapiens_hsa030100.45814272
147Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054100.45461821
148Basal cell carcinoma_Homo sapiens_hsa052170.45067206
149Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010400.44975192
150Circadian rhythm_Homo sapiens_hsa047100.43347243
151Basal transcription factors_Homo sapiens_hsa030220.42493782
152Hedgehog signaling pathway_Homo sapiens_hsa043400.42328569
153Sphingolipid signaling pathway_Homo sapiens_hsa040710.41931660
154Biosynthesis of amino acids_Homo sapiens_hsa012300.41043880
155Drug metabolism - other enzymes_Homo sapiens_hsa009830.40887419
156Chemical carcinogenesis_Homo sapiens_hsa052040.40575137
157Vitamin digestion and absorption_Homo sapiens_hsa049770.40012572
158Chemokine signaling pathway_Homo sapiens_hsa040620.39962877
159Dilated cardiomyopathy_Homo sapiens_hsa054140.39940870
160NF-kappa B signaling pathway_Homo sapiens_hsa040640.39256025
161MAPK signaling pathway_Homo sapiens_hsa040100.37724351
162Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047500.37508127
163cGMP-PKG signaling pathway_Homo sapiens_hsa040220.36283973
164Vibrio cholerae infection_Homo sapiens_hsa051100.36254284
165Regulation of actin cytoskeleton_Homo sapiens_hsa048100.36207321

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