S100A11

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein may function in motility, invasion, and tubulin polymerization. Chromosomal rearrangements and altered expression of this gene have been implicated in tumor metastasis. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1neutrophil activation involved in immune response (GO:0002283)4.87983642
2desmosome organization (GO:0002934)4.07052060
3hemidesmosome assembly (GO:0031581)3.99577566
4wound healing, spreading of epidermal cells (GO:0035313)3.78788870
5antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G3.68713863
6neutrophil activation (GO:0042119)3.55811855
7granulocyte activation (GO:0036230)3.48975062
8negative regulation of interleukin-12 production (GO:0032695)3.44566239
9positive regulation of Cdc42 GTPase activity (GO:0043089)3.37369597
10cellular response to interferon-alpha (GO:0035457)3.35476091
11response to peptidoglycan (GO:0032494)3.35195581
12regulation of interleukin-8 secretion (GO:2000482)3.31145564
13positive regulation of monocyte chemotaxis (GO:0090026)3.26765567
14cell adhesion mediated by integrin (GO:0033627)3.26559670
15leukocyte aggregation (GO:0070486)3.26420348
16regulation of interferon-beta biosynthetic process (GO:0045357)3.19775269
17wound healing, spreading of cells (GO:0044319)3.14869685
18negative regulation of cell killing (GO:0031342)3.13978971
19negative regulation of leukocyte mediated cytotoxicity (GO:0001911)3.13978971
20positive regulation of syncytium formation by plasma membrane fusion (GO:0060143)3.06475197
21barbed-end actin filament capping (GO:0051016)3.03059189
22protein localization to endosome (GO:0036010)3.00733210
23regulation of monocyte chemotaxis (GO:0090025)2.98677087
24membrane raft organization (GO:0031579)2.97149165
25interferon-gamma secretion (GO:0072643)2.96029360
26endodermal cell differentiation (GO:0035987)2.91167395
27skin morphogenesis (GO:0043589)2.91084343
28respiratory burst (GO:0045730)2.90020945
29positive regulation of tumor necrosis factor biosynthetic process (GO:0042535)2.87693253
30detection of other organism (GO:0098543)2.87189445
31production of molecular mediator involved in inflammatory response (GO:0002532)2.81902426
32response to interferon-alpha (GO:0035455)2.81840878
33modulation by organism of defense response of other organism involved in symbiotic interaction (GO:02.81560815
34positive regulation by organism of defense response of other organism involved in symbiotic interact2.81560815
35modulation by symbiont of host immune response (GO:0052553)2.81560815
36positive regulation by symbiont of host defense response (GO:0052509)2.81560815
37modulation by symbiont of host defense response (GO:0052031)2.81560815
38modulation by organism of immune response of other organism involved in symbiotic interaction (GO:002.81560815
39hepatocyte apoptotic process (GO:0097284)2.81329844
40negative regulation of endoplasmic reticulum calcium ion concentration (GO:0032471)2.80941853
41Arp2/3 complex-mediated actin nucleation (GO:0034314)2.80423321
42response to muramyl dipeptide (GO:0032495)2.77766661
43regulation of chemokine secretion (GO:0090196)2.77748866
44regulation of natural killer cell differentiation (GO:0032823)2.75398135
45cellular response to zinc ion (GO:0071294)2.74637062
46positive regulation of endothelial cell apoptotic process (GO:2000353)2.74190258
47positive regulation of natural killer cell differentiation (GO:0032825)2.73133167
48response to defenses of other organism involved in symbiotic interaction (GO:0052173)2.68567056
49response to host (GO:0075136)2.68567056
50response to host defenses (GO:0052200)2.68567056
51regulation of T-helper 2 cell differentiation (GO:0045628)2.68149362
52regulation of hypersensitivity (GO:0002883)2.68130807
53sequestering of actin monomers (GO:0042989)2.67308799
54regulation of integrin-mediated signaling pathway (GO:2001044)2.66774579
55regulation of mast cell degranulation (GO:0043304)2.64633297
56myeloid cell homeostasis (GO:0002262)2.64394493
57detection of bacterium (GO:0016045)2.64301217
58pinocytosis (GO:0006907)2.62790460
59negative regulation of interleukin-8 production (GO:0032717)2.62465974
60interferon-gamma-mediated signaling pathway (GO:0060333)2.62341103
61negative regulation of cytokine production involved in immune response (GO:0002719)2.62311912
62detection of biotic stimulus (GO:0009595)2.61916009
63regulation of syncytium formation by plasma membrane fusion (GO:0060142)2.61128335
64NIK/NF-kappaB signaling (GO:0038061)2.60438312
65immunoglobulin mediated immune response (GO:0016064)2.59568320
66positive regulation of actin filament depolymerization (GO:0030836)2.57678805
67membrane budding (GO:0006900)2.57568583
68amino sugar catabolic process (GO:0046348)2.57364497
69pyrimidine-containing compound salvage (GO:0008655)2.57290562
70pyrimidine nucleoside salvage (GO:0043097)2.57290562
71ribosomal small subunit assembly (GO:0000028)2.57237557
72negative regulation of toll-like receptor 4 signaling pathway (GO:0034144)2.56971694
73mesodermal cell differentiation (GO:0048333)2.56379711
74viral transcription (GO:0019083)2.56371687
75COPI coating of Golgi vesicle (GO:0048205)2.56266502
76Golgi transport vesicle coating (GO:0048200)2.56266502
77sequestering of metal ion (GO:0051238)2.53825386
78hydrogen peroxide biosynthetic process (GO:0050665)2.53761714
79regulation of superoxide anion generation (GO:0032928)2.52687432
80B cell mediated immunity (GO:0019724)2.48645656
81regulation of mononuclear cell migration (GO:0071675)2.47949843
82positive regulation of nitric-oxide synthase biosynthetic process (GO:0051770)2.47779442
83superoxide anion generation (GO:0042554)2.47645387
84positive regulation of membrane protein ectodomain proteolysis (GO:0051044)2.47286473
85antigen processing and presentation of exogenous peptide antigen via MHC class I (GO:0042590)2.46663753
86negative regulation of nitric oxide biosynthetic process (GO:0045019)2.46565066
87regulation of dendritic cell antigen processing and presentation (GO:0002604)2.45037601
88regulation of leukocyte degranulation (GO:0043300)2.45005001
89regulation of apoptotic process involved in morphogenesis (GO:1902337)2.44283502
90positive regulation of chemokine biosynthetic process (GO:0045080)2.43484301
91regulation of T cell tolerance induction (GO:0002664)2.43244120
92keratinocyte differentiation (GO:0030216)2.42488745
93translational termination (GO:0006415)2.42240516
94regulation of tolerance induction (GO:0002643)2.41241021
95regulation of podosome assembly (GO:0071801)2.40692823
96positive regulation of interferon-alpha production (GO:0032727)2.40660047
97glycosphingolipid catabolic process (GO:0046479)2.40380078
98negative regulation of inflammatory response to antigenic stimulus (GO:0002862)2.39521610
99response to progesterone (GO:0032570)2.39229214
100myeloid dendritic cell differentiation (GO:0043011)2.39224264
101antigen processing and presentation of endogenous antigen (GO:0019883)2.39197677
102macrophage activation (GO:0042116)2.38853271
103natural killer cell mediated cytotoxicity (GO:0042267)2.38798734
104natural killer cell mediated immunity (GO:0002228)2.38798734
105T-helper 1 type immune response (GO:0042088)2.37282571
106positive regulation of interleukin-6 production (GO:0032755)2.37213175
107SRP-dependent cotranslational protein targeting to membrane (GO:0006614)2.37054827
108reactive oxygen species biosynthetic process (GO:1903409)2.36982424
109regulation of myeloid leukocyte mediated immunity (GO:0002886)2.36732296
110antigen processing and presentation of endogenous peptide antigen (GO:0002483)2.36390361
111antigen processing and presentation of endogenous peptide antigen via MHC class I (GO:0019885)2.36390361
112positive regulation of type 2 immune response (GO:0002830)2.35975721
113regulation of mast cell activation involved in immune response (GO:0033006)2.35455147
114positive regulation of gamma-delta T cell activation (GO:0046645)2.35073575
115regulation of vitamin D biosynthetic process (GO:0060556)2.34816626
116negative regulation of interferon-gamma production (GO:0032689)2.34749307
117antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent (GO:2.34422697
118regulation of tumor necrosis factor biosynthetic process (GO:0042534)2.33665011
119lipoxygenase pathway (GO:0019372)2.33498179
120hypotonic response (GO:0006971)2.33310988
121positive regulation of interleukin-8 secretion (GO:2000484)2.33089181
122detection of external biotic stimulus (GO:0098581)2.32877696
123macrophage activation involved in immune response (GO:0002281)2.32629876
124germinal center formation (GO:0002467)2.32062609
125cellular extravasation (GO:0045123)2.31469869
126protein targeting to ER (GO:0045047)2.31082631
127regulation of chemokine biosynthetic process (GO:0045073)2.30303156
128amyloid precursor protein catabolic process (GO:0042987)2.29764892
129lipopolysaccharide-mediated signaling pathway (GO:0031663)2.29583240
130regulation of water loss via skin (GO:0033561)2.29088573
131regulation of interleukin-6 production (GO:0032675)2.28836981
132dendritic cell chemotaxis (GO:0002407)2.28053183
133response to fungus (GO:0009620)2.27513050
134regulation of branching involved in salivary gland morphogenesis (GO:0060693)2.26593218
135cotranslational protein targeting to membrane (GO:0006613)2.26347898
136positive regulation of chemokine secretion (GO:0090197)2.25081511
137regulation of interferon-alpha production (GO:0032647)2.24106857
138leukocyte mediated cytotoxicity (GO:0001909)2.24036871
139dendritic cell migration (GO:0036336)2.23723934
140positive regulation of tumor necrosis factor superfamily cytokine production (GO:1903557)2.23528055
141positive regulation of vesicle fusion (GO:0031340)2.22869035
142positive regulation of antigen processing and presentation (GO:0002579)2.22563157
143response to type I interferon (GO:0034340)2.22175949
144response to immune response of other organism involved in symbiotic interaction (GO:0052564)2.21948848
145response to host immune response (GO:0052572)2.21948848
146myeloid cell activation involved in immune response (GO:0002275)2.21147578
147ribosomal small subunit biogenesis (GO:0042274)2.21132068
148cellular response to type I interferon (GO:0071357)2.20725015
149type I interferon signaling pathway (GO:0060337)2.20725015
150detection of molecule of bacterial origin (GO:0032490)2.20342857
151positive regulation of macrophage differentiation (GO:0045651)2.19736238
152regulation of metalloenzyme activity (GO:0048552)2.19134345
153actin nucleation (GO:0045010)2.19036590
154response to interferon-beta (GO:0035456)2.18865822

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1TP63_17297297_ChIP-ChIP_HaCaT_Human9.31583366
2TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse4.63453803
3TRIM28_21343339_ChIP-Seq_HEK293_Human4.11915167
4IRF8_22096565_ChIP-ChIP_GC-B_Human3.56977741
5IRF8_21731497_ChIP-ChIP_J774_Mouse3.41235658
6RARG_19884340_ChIP-ChIP_MEFs_Mouse3.27230164
7FOXP3_17237761_ChIP-ChIP_TREG_Mouse3.26876828
8EGR1_19374776_ChIP-ChIP_THP-1_Human2.91041853
9BP1_19119308_ChIP-ChIP_Hs578T_Human2.90999105
10RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human2.82047623
11SMAD4_19686287_ChIP-ChIP_HaCaT_Human2.80135649
12MYB_21317192_ChIP-Seq_ERMYB_Mouse2.58923396
13NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse2.40056060
14NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse2.29659481
15SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse2.23546227
16IRF8_27001747_Chip-Seq_BMDM_Mouse2.19830819
17Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse2.19184161
18SMAD3_18955504_ChIP-ChIP_HaCaT_Human2.15171646
19SMAD2_18955504_ChIP-ChIP_HaCaT_Human2.15171646
20* STAT6_20620947_ChIP-Seq_CD4_POS_T_Human2.11669651
21MECOM_23826213_ChIP-Seq_KASUMI_Mouse1.97840586
22IRF8_22096565_ChIP-ChIP_GC-B_Mouse1.93313558
23STAT5_23275557_ChIP-Seq_MAMMARY-EPITHELIUM_Mouse1.91527368
24* STAT3_20064451_ChIP-Seq_CD4+T_Mouse1.88193907
25TCF21_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human1.86809860
26IRF1_21803131_ChIP-Seq_MONOCYTES_Human1.84416987
27CEBPB_21427703_ChIP-Seq_3T3-L1_Mouse1.79343656
28* P63_26484246_Chip-Seq_KERATINOCYTES_Human1.78419962
29ESR1_21235772_ChIP-Seq_MCF-7_Human1.78251904
30STAT6_21828071_ChIP-Seq_BEAS2B_Human1.77110694
31NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human1.73726670
32SOX2_20726797_ChIP-Seq_SW620_Human1.70829062
33* CJUN_26792858_Chip-Seq_BT549_Human1.67576277
34BRD4_27068464_Chip-Seq_AML-cells_Mouse1.65977370
35ATF3_23680149_ChIP-Seq_GBM1-GSC_Human1.63013334
36STAT4_19710469_ChIP-ChIP_TH1__Mouse1.61800141
37* RUNX2_24764292_ChIP-Seq_MC3T3_Mouse1.60578427
38LXR_22292898_ChIP-Seq_THP-1_Human1.55879191
39CLOCK_20551151_ChIP-Seq_293T_Human1.54172845
40HIF1A_21447827_ChIP-Seq_MCF-7_Human1.52125527
41TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat1.51656842
42STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse1.47553724
43* SPI1_23547873_ChIP-Seq_NB4_Human1.47509413
44ELK3_25401928_ChIP-Seq_HUVEC_Human1.46777824
45SMARCA4_20176728_ChIP-ChIP_TSCs_Mouse1.46162235
46PPARD_23176727_ChIP-Seq_KERATINOCYTES_Mouse1.45050204
47SPI1_22096565_ChIP-ChIP_GC-B_Mouse1.43747169
48THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse1.40895257
49FOXO3_23340844_ChIP-Seq_DLD1_Human1.38428944
50* GATA2_21666600_ChIP-Seq_HMVEC_Human1.38318079
51SOX9_24532713_ChIP-Seq_HFSC_Mouse1.38172759
52CEBPD_21427703_ChIP-Seq_3T3-L1_Mouse1.36429767
53* KLF6_26769127_Chip-Seq_PDAC-Cell_line_Human1.35185995
54* JUND_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human1.33638506
55CHD7_19251738_ChIP-ChIP_MESCs_Mouse1.33043910
56MYB_26560356_Chip-Seq_TH2_Human1.31742463
57PPAR_26484153_Chip-Seq_NCI-H1993_Human1.27426130
58ELK1_22589737_ChIP-Seq_MCF10A_Human1.27422191
59VDR_24763502_ChIP-Seq_THP-1_Human1.26765764
60ELF1_17652178_ChIP-ChIP_JURKAT_Human1.26164403
61ESR2_21235772_ChIP-Seq_MCF-7_Human1.24956527
62PU.1_20513432_ChIP-Seq_MACROPHAGES_Mouse1.22858792
63EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse1.22371392
64CEBPB_20176806_ChIP-Seq_MACROPHAGES_Mouse1.21940487
65TAF7L_23326641_ChIP-Seq_C3H10T1-2_Mouse1.20667980
66* MAF_26560356_Chip-Seq_TH1_Human1.18796803
67ATF3_27146783_Chip-Seq_COLON_Human1.18748710
68SPI1_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse1.18648382
69MEIS1_20887958_ChIP-Seq_HPC-7_Mouse1.18052665
70HSF1_23293686_ChIP-Seq_STHDH_STRIATAL_Mouse1.17029466
71ZNF263_19887448_ChIP-Seq_K562_Human1.16874435
72* JUN_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human1.16866542
73TFEB_21752829_ChIP-Seq_HELA_Human1.16457556
74RUNX1_20887958_ChIP-Seq_HPC-7_Mouse1.15685243
75KDM2B_26808549_Chip-Seq_SUP-B15_Human1.14937966
76RUNX1_22412390_ChIP-Seq_EML_Mouse1.14269389
77NRF2_20460467_ChIP-Seq_MEFs_Mouse1.13306167
78NFE2L2_20460467_ChIP-Seq_MEFs_Mouse1.13306167
79* KLF4_26769127_Chip-Seq_PDAC-Cell_line_Human1.12161450
80PPARG_19300518_ChIP-PET_3T3-L1_Mouse1.10339689
81* BRD4_25478319_ChIP-Seq_HGPS_Human1.09925779
82* UBF1/2_26484160_Chip-Seq_HMECs_Human1.09239745
83PU_27001747_Chip-Seq_BMDM_Mouse1.08893571
84TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse1.08619926
85* FOXA1_26769127_Chip-Seq_PDAC-Cell_line_Human1.07942777
86E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human1.04600970
87CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human1.04440369
88* RACK7_27058665_Chip-Seq_MCF-7_Human1.03943476
89ASXL1_24218140_ChIP-Seq_BMDM_Mouse1.03579450
90ESR1_20079471_ChIP-ChIP_T-47D_Human1.03436947
91VDR_24787735_ChIP-Seq_THP-1_Human1.02453621
92* UBF1/2_26484160_Chip-Seq_HMEC-DERIVED_Human1.02032229
93* KDM2B_26808549_Chip-Seq_SIL-ALL_Human1.01949495
94TFAP2C_20629094_ChIP-Seq_MCF-7_Human1.01882678
95CEBPB_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse1.01726707
96CDX2_20551321_ChIP-Seq_CACO-2_Human1.00988041
97* ELF3_26769127_Chip-Seq_PDAC-Cell_line_Human1.00149211
98* GATA4_25053715_ChIP-Seq_YYC3_Human1.00118063
99SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse1.00080676
100* MAF_26560356_Chip-Seq_TH2_Human0.99605280
101SRY_22984422_ChIP-ChIP_TESTIS_Rat0.98494012
102* TCF7_22412390_ChIP-Seq_EML_Mouse0.98394865
103LMO2_20887958_ChIP-Seq_HPC-7_Mouse0.98011632
104P300_27058665_Chip-Seq_ZR-75-30cells_Human0.97824728
105GATA1_22383799_ChIP-Seq_G1ME_Mouse0.97289145
106MYB_26560356_Chip-Seq_TH1_Human0.95398418
107PPARA_22158963_ChIP-Seq_LIVER_Mouse0.94963693
108TCFAP2C_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse0.94063464
109ELK1_19687146_ChIP-ChIP_HELA_Human0.93413110
110CEBPA_20513432_ChIP-Seq_MACROPHAGES_Mouse0.93322242
111RXR_22158963_ChIP-Seq_LIVER_Mouse0.93173531
112RUNX_20019798_ChIP-Seq_JUKART_Human0.90781120
113VDR_21846776_ChIP-Seq_THP-1_Human0.90150237
114SALL4_18804426_ChIP-ChIP_XEN_Mouse0.89367680
115SMAD_19615063_ChIP-ChIP_OVARY_Human0.86064512
116CEBPB_20513432_ChIP-Seq_MACROPHAGES_Mouse0.85002660
117* GATA3_24758297_ChIP-Seq_MCF-7_Human0.84441541
118* FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse0.84066699
119EOMES_20176728_ChIP-ChIP_TSCs_Mouse0.83934478
120* KLF5_25053715_ChIP-Seq_YYC3_Human0.82721087
121FLI1_20887958_ChIP-Seq_HPC-7_Mouse0.82253049
122* SOX2_27498859_Chip-Seq_STOMACH_Mouse0.81161955
123* UTX_26944678_Chip-Seq_JUKART_Human0.80829241
124PU.1_20176806_ChIP-Seq_MACROPHAGES_Mouse0.80750209
125KLF4_18358816_ChIP-ChIP_MESCs_Mouse0.79130389
126* GATA6_25053715_ChIP-Seq_YYC3_Human0.77797217
127FOXA1_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human0.77615700
128* SPI1_23127762_ChIP-Seq_K562_Human0.77532726

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0003191_abnormal_cellular_cholesterol3.27312827
2MP0003436_decreased_susceptibility_to3.06358879
3MP0005275_abnormal_skin_tensile3.02300170
4MP0008438_abnormal_cutaneous_collagen2.84294755
5MP0003566_abnormal_cell_adhesion2.52136776
6MP0001835_abnormal_antigen_presentation2.44153693
7MP0009785_altered_susceptibility_to2.38119400
8MP0002148_abnormal_hypersensitivity_rea2.35282597
9MP0003806_abnormal_nucleotide_metabolis2.29826357
10MP0003705_abnormal_hypodermis_morpholog2.29078660
11MP0010352_gastrointestinal_tract_polyps2.12652728
12MP0009840_abnormal_foam_cell2.01321653
13MP0003724_increased_susceptibility_to1.99362490
14MP0002060_abnormal_skin_morphology1.99268876
15MP0002796_impaired_skin_barrier1.97194273
16MP0003453_abnormal_keratinocyte_physiol1.93073835
17MP0000858_altered_metastatic_potential1.93030828
18MP0001533_abnormal_skeleton_physiology1.91481863
19MP0005023_abnormal_wound_healing1.91451336
20MP0000685_abnormal_immune_system1.89775028
21MP0002419_abnormal_innate_immunity1.88812435
22MP0002254_reproductive_system_inflammat1.87753370
23MP0002877_abnormal_melanocyte_morpholog1.84682861
24MP0003279_aneurysm1.81748781
25MP0005000_abnormal_immune_tolerance1.80531477
26MP0008260_abnormal_autophagy1.79954336
27MP0004947_skin_inflammation1.79131759
28MP0003941_abnormal_skin_development1.75312698
29MP0005025_abnormal_response_to1.75120368
30MP0006054_spinal_hemorrhage1.74465321
31MP0003303_peritoneal_inflammation1.73693783
32MP0001958_emphysema1.70501356
33MP0010234_abnormal_vibrissa_follicle1.65764548
34MP0004272_abnormal_basement_membrane1.63407349
35MP0003448_altered_tumor_morphology1.61562842
36MP0002006_tumorigenesis1.59158890
37MP0001853_heart_inflammation1.57882494
38MP0005503_abnormal_tendon_morphology1.57863697
39MP0005387_immune_system_phenotype1.56319439
40MP0001790_abnormal_immune_system1.56319439
41MP0005451_abnormal_body_composition1.55292953
42MP0001216_abnormal_epidermal_layer1.54909153
43MP0000343_altered_response_to1.50823666
44MP0002405_respiratory_system_inflammati1.47896028
45MP0003950_abnormal_plasma_membrane1.46894358
46MP0002452_abnormal_antigen_presenting1.45879881
47MP0002166_altered_tumor_susceptibility1.44985409
48MP0005390_skeleton_phenotype1.40084762
49MP0005076_abnormal_cell_differentiation1.35958670
50MP0005501_abnormal_skin_physiology1.35800066
51MP0003172_abnormal_lysosome_physiology1.34930175
52MP0002132_abnormal_respiratory_system1.34803515
53MP0008469_abnormal_protein_level1.30583171
54MP0003300_gastrointestinal_ulcer1.30352388
55MP0000383_abnormal_hair_follicle1.29390737
56MP0005166_decreased_susceptibility_to1.29133224
57MP0001346_abnormal_lacrimal_gland1.28300342
58MP0010155_abnormal_intestine_physiology1.27708945
59MP0002723_abnormal_immune_serum1.26249403
60MP0002933_joint_inflammation1.26162641
61MP0006082_CNS_inflammation1.26116239
62MP0001819_abnormal_immune_cell1.25883554
63MP0004782_abnormal_surfactant_physiolog1.24590548
64MP0002420_abnormal_adaptive_immunity1.23660443
65MP0002998_abnormal_bone_remodeling1.22396246
66MP0001845_abnormal_inflammatory_respons1.18533418
67MP0005165_increased_susceptibility_to1.18354381
68MP0001542_abnormal_bone_strength1.18078645
69MP0001851_eye_inflammation1.17791472
70MP0005397_hematopoietic_system_phenotyp1.17411274
71MP0001545_abnormal_hematopoietic_system1.17411274
72MP0009278_abnormal_bone_marrow1.17018216
73MP0001800_abnormal_humoral_immune1.15112224
74MP0009764_decreased_sensitivity_to1.15032556
75MP0009384_cardiac_valve_regurgitation1.14735219
76MP0001849_ear_inflammation1.14188769
77MP0002098_abnormal_vibrissa_morphology1.14049931
78MP0005671_abnormal_response_to1.13878046
79MP0003091_abnormal_cell_migration1.11649422
80MP0005464_abnormal_platelet_physiology1.11607269
81MP0003828_pulmonary_edema1.10131483
82MP0005164_abnormal_response_to1.09023124
83MP0001243_abnormal_dermal_layer1.06927362
84MP0010678_abnormal_skin_adnexa1.06898513
85MP0002295_abnormal_pulmonary_circulatio1.05430472
86MP0003186_abnormal_redox_activity1.04690043
87MP0010771_integument_phenotype1.02711828
88MP0008004_abnormal_stomach_pH1.02165908
89MP0005508_abnormal_skeleton_morphology1.00390543
90MP0004264_abnormal_extraembryonic_tissu0.98176762
91MP0009333_abnormal_splenocyte_physiolog0.97866234
92MP0001879_abnormal_lymphatic_vessel0.96085686
93MP0003795_abnormal_bone_structure0.95449059
94MP0002282_abnormal_trachea_morphology0.95401629
95MP0005058_abnormal_lysosome_morphology0.94591339
96MP0005310_abnormal_salivary_gland0.94019145
97MP0000627_abnormal_mammary_gland0.93100107
98MP0000377_abnormal_hair_follicle0.92341872
99MP0003763_abnormal_thymus_physiology0.91634617
100MP0005623_abnormal_meninges_morphology0.90668330
101MP0001191_abnormal_skin_condition0.90043708
102MP0005257_abnormal_intraocular_pressure0.89451954
103MP0009053_abnormal_anal_canal0.87574610
104MP0009931_abnormal_skin_appearance0.87454298
105MP0000604_amyloidosis0.83472532
106MP0000767_abnormal_smooth_muscle0.82709817
107MP0001873_stomach_inflammation0.82145902
108MP0000733_abnormal_muscle_development0.82049703
109MP0004883_abnormal_blood_vessel0.81478247
110MP0000678_abnormal_parathyroid_gland0.81312509
111MP0000465_gastrointestinal_hemorrhage0.81162566
112MP0004381_abnormal_hair_follicle0.80800678
113MP0004510_myositis0.79351167
114MP0002277_abnormal_respiratory_mucosa0.78831067
115MP0000716_abnormal_immune_system0.78142491
116MP0002429_abnormal_blood_cell0.78004850
117MP0002398_abnormal_bone_marrow0.77748803
118MP0000490_abnormal_crypts_of0.77699222
119MP0005083_abnormal_biliary_tract0.77609530
120MP0003075_altered_response_to0.77499942
121MP0003045_fibrosis0.76999096
122MP0009763_increased_sensitivity_to0.75958348
123MP0004858_abnormal_nervous_system0.75103561
124MP0003866_abnormal_defecation0.74803240
125MP0002009_preneoplasia0.74718558
126MP0002332_abnormal_exercise_endurance0.73804553
127MP0000579_abnormal_nail_morphology0.73214331

Predicted human phenotypes

RankGene SetZ-score
1Abnormality of glycolipid metabolism (HP:0010969)4.94227316
2Abnormality of liposaccharide metabolism (HP:0010968)4.94227316
3Abnormality of glycosphingolipid metabolism (HP:0004343)4.94227316
4Eczematoid dermatitis (HP:0000976)4.85637054
5Recurrent abscess formation (HP:0002722)4.30321368
6Recurrent bacterial skin infections (HP:0005406)3.82404676
7Atrophic scars (HP:0001075)3.76937999
8Protrusio acetabuli (HP:0003179)3.53236582
9Premature rupture of membranes (HP:0001788)3.48576316
10Onycholysis (HP:0001806)3.43653721
11Interstitial pulmonary disease (HP:0006530)3.31418295
12Myositis (HP:0100614)3.13971380
13Loss of speech (HP:0002371)3.13752391
14Osteolytic defects of the hand bones (HP:0009699)3.11759088
15Osteolytic defects of the phalanges of the hand (HP:0009771)3.11759088
16Recurrent gram-negative bacterial infections (HP:0005420)3.09918185
17Vertebral compression fractures (HP:0002953)3.09333814
18Dysostosis multiplex (HP:0000943)3.00834241
19Orchitis (HP:0100796)3.00730448
20Fragile nails (HP:0001808)2.92782957
21Cervical subluxation (HP:0003308)2.92195525
22Peritonitis (HP:0002586)2.91811424
23Plantar hyperkeratosis (HP:0007556)2.91430493
24Elevated erythrocyte sedimentation rate (HP:0003565)2.91052448
25Milia (HP:0001056)2.89537655
26Abnormality of macrophages (HP:0004311)2.86590984
27Right ventricular cardiomyopathy (HP:0011663)2.79583760
28Amyloidosis (HP:0011034)2.73292519
29Thick nail (HP:0001805)2.72550114
30Systemic lupus erythematosus (HP:0002725)2.70933330
31Pustule (HP:0200039)2.64047367
32Mediastinal lymphadenopathy (HP:0100721)2.61904993
33Abnormal hemoglobin (HP:0011902)2.61214510
34Abnormality of polysaccharide metabolism (HP:0011012)2.59162657
35Abnormality of glycosaminoglycan metabolism (HP:0004371)2.59162657
36Abnormality of mucopolysaccharide metabolism (HP:0011020)2.59162657
37Nasal polyposis (HP:0100582)2.54512785
38Nuclear cataract (HP:0100018)2.52255672
39Autoimmune thrombocytopenia (HP:0001973)2.52095041
40Vacuolated lymphocytes (HP:0001922)2.50690318
41Stomatitis (HP:0010280)2.49670588
42Mucopolysacchariduria (HP:0008155)2.48900634
43Urinary glycosaminoglycan excretion (HP:0003541)2.48900634
44Gingivitis (HP:0000230)2.48185254
45Hepatosplenomegaly (HP:0001433)2.47043052
46Chronic obstructive pulmonary disease (HP:0006510)2.42119387
47Obstructive lung disease (HP:0006536)2.42119387
48Progressive neurologic deterioration (HP:0002344)2.37448880
49Abnormality of the distal phalanges of the toes (HP:0010182)2.33987488
50Periodontitis (HP:0000704)2.32369965
51Aortic aneurysm (HP:0004942)2.29894059
52Aortic dissection (HP:0002647)2.28889067
53Malnutrition (HP:0004395)2.28584416
54Increased serum ferritin (HP:0003281)2.27463999
55Fragile skin (HP:0001030)2.23245458
56Hypotrichosis (HP:0001006)2.23127088
57Recurrent fungal infections (HP:0002841)2.22397849
58Optic neuritis (HP:0100653)2.21668581
59Retrobulbar optic neuritis (HP:0100654)2.21668581
60Rough bone trabeculation (HP:0100670)2.19514660
61Congenital nonbullous ichthyosiform erythroderma (HP:0007479)2.18679275
62Recurrent skin infections (HP:0001581)2.17843043
63Dilatation of the ascending aorta (HP:0005111)2.16955103
64Palmoplantar hyperkeratosis (HP:0000972)2.16607080
65Skin ulcer (HP:0200042)2.13984399
66Disinhibition (HP:0000734)2.13488208
67Cellulitis (HP:0100658)2.13345239
68Wormian bones (HP:0002645)2.10210142
69Pili torti (HP:0003777)2.09339455
70Purpura (HP:0000979)2.08729789
71Vascular tortuosity (HP:0004948)2.05918822
72Short nail (HP:0001799)2.05111240
73Woolly hair (HP:0002224)2.03760495
74Nail dystrophy (HP:0008404)2.03030795
75Urticaria (HP:0001025)2.02906882
76Abnormality of nail color (HP:0100643)2.02514593
77Anhidrosis (HP:0000970)2.01156031
78Abnormality of the pericardium (HP:0001697)1.99433120
79Palmar hyperkeratosis (HP:0010765)1.97975545
80Alopecia of scalp (HP:0002293)1.96861964
81Soft skin (HP:0000977)1.96014204
82Increased IgE level (HP:0003212)1.93430440
83Oral leukoplakia (HP:0002745)1.92773762
84Distal lower limb muscle weakness (HP:0009053)1.91914388
85Reticulocytopenia (HP:0001896)1.91270800
86Axonal loss (HP:0003447)1.91035086
87Spinal rigidity (HP:0003306)1.90623081
88Spondylolisthesis (HP:0003302)1.89629366
89Ankle contracture (HP:0006466)1.88510609
90Myocardial infarction (HP:0001658)1.88208710
91Spinal cord lesions (HP:0100561)1.87042406
92Syringomyelia (HP:0003396)1.87042406
93Beaking of vertebral bodies (HP:0004568)1.86723928
94Parakeratosis (HP:0001036)1.86652505
95Sparse eyelashes (HP:0000653)1.86354852
96Erythema (HP:0010783)1.84436417
97Hypergammaglobulinemia (HP:0010702)1.84390859
98Increased neuronal autofluorescent lipopigment (HP:0002074)1.83609947
99Reduced subcutaneous adipose tissue (HP:0003758)1.82963168
100Abnormal trabecular bone morphology (HP:0100671)1.82669481
101Prolonged neonatal jaundice (HP:0006579)1.82299800
102Vasculitis (HP:0002633)1.82013075
103Keratoconjunctivitis sicca (HP:0001097)1.81419992
104Abnormality of iron homeostasis (HP:0011031)1.78896173
105Hypertensive crisis (HP:0100735)1.78688468
106Thrombocytosis (HP:0001894)1.78542426
107Vascular calcification (HP:0004934)1.78419636
108Shallow orbits (HP:0000586)1.77932605
109Natal tooth (HP:0000695)1.77307258
110Anorexia (HP:0002039)1.76635635
111Polygenic inheritance (HP:0010982)1.76588733
112Osteomyelitis (HP:0002754)1.75810561
113Increased cerebral lipofuscin (HP:0011813)1.75012145
114Cardiovascular calcification (HP:0011915)1.74684791
115Bone pain (HP:0002653)1.74429519
116Pathologic fracture (HP:0002756)1.74372978
117Episodic fever (HP:0001954)1.74275738
118Trismus (HP:0000211)1.74215435
119Cerebral aneurysm (HP:0004944)1.73610743
120Cheilitis (HP:0100825)1.71374712
121Arterial tortuosity (HP:0005116)1.71352622
122Congenital, generalized hypertrichosis (HP:0004540)1.70688729
123Lip pit (HP:0100267)1.70364425
124Micronodular cirrhosis (HP:0001413)1.70080075
125Abnormal blistering of the skin (HP:0008066)1.69804447
126Increased IgM level (HP:0003496)1.69271505
127Congenital ichthyosiform erythroderma (HP:0007431)1.68703114
128Pulmonary infiltrates (HP:0002113)1.67478010
129Hematochezia (HP:0002573)1.67380790
130Follicular hyperkeratosis (HP:0007502)1.67180796
131Broad face (HP:0000283)1.66274540
132Elbow flexion contracture (HP:0002987)1.65768521
133Increased connective tissue (HP:0009025)1.64510514
134Neonatal short-limb short stature (HP:0008921)1.63891228
135Blue sclerae (HP:0000592)1.61188493
136Premature loss of primary teeth (HP:0006323)1.57971421
137Biconcave vertebral bodies (HP:0004586)1.57195296
138Petechiae (HP:0000967)1.57051121
139Abnormality of the nasal mucosa (HP:0000433)1.56791712
140Hemoptysis (HP:0002105)1.56699932

Predicted kinase interactions (KEA)

RankGene SetZ-score
1EPHA23.13583124
2TESK13.11029986
3PIM23.09314639
4ERN12.68817851
5MST42.67263614
6MAP3K142.47624076
7TRPM72.46152837
8MST1R2.36637809
9NME22.28295290
10MAP3K32.25822701
11SIK32.19722050
12RPS6KA42.19062871
13ERBB32.16240799
14LRRK22.15492031
15BLK2.03746994
16TBK11.84361637
17PBK1.76428814
18STK101.76126804
19IRAK41.70608126
20LIMK11.62550766
21TRIB31.55461935
22TYK21.55194008
23EPHB11.48470675
24EPHB21.47201505
25IKBKB1.46993286
26MAPKAPK31.46334995
27NEK91.44791505
28PIK3CG1.37545819
29SIK11.36525516
30JAK31.35998518
31TTN1.34738483
32IRAK31.33768744
33SMG11.32621050
34EPHA31.29852450
35PAK41.27034897
36GRK71.26615367
37TGFBR21.26466329
38BMX1.23201571
39PTK21.20243823
40RPS6KB21.16120827
41TESK21.13603055
42PRPF4B1.12467834
43PTK61.10416662
44ZAP701.10159537
45IKBKE1.09298978
46CSK1.07851820
47FER1.05059093
48RIPK41.05002505
49FRK1.04435900
50CHUK1.04396357
51MAP3K121.04046765
52MAP2K31.03342269
53FGR1.02356754
54ILK1.01857366
55TEC1.00320397
56KDR1.00250051
57STK241.00197414
58GRK60.99883217
59LMTK20.99470704
60MYLK0.99369793
61MAP3K110.96869203
62MET0.96757168
63BTK0.95841721
64DDR20.95177777
65VRK20.95003280
66PIM10.90654011
67JAK10.87992730
68STK30.87591707
69RIPK10.86828788
70MAP4K10.85357854
71ABL20.84026583
72PRKG20.83870431
73CDK60.82695523
74CDC42BPA0.80917585
75MAPKAPK20.80812720
76MOS0.79933325
77KIT0.75374534
78HCK0.74638759
79LATS10.74301016
80PRKD20.74197330
81MAP3K20.69123113
82CSF1R0.67477518
83MAP2K20.67369624
84MAP3K130.66849187
85BMPR20.65565373
86FGFR40.63729619
87STK380.62387451
88TGFBR10.62148173
89MATK0.61329791
90TNK20.60980796
91DMPK0.60137486
92FGFR30.60134439
93MAP3K60.59609260
94ITK0.57225740
95DYRK1B0.57139369
96TXK0.56694809
97MAP2K10.55681656
98ABL10.55324882
99PAK20.55106082
100NUAK10.54151097
101TAOK20.53424689
102TAOK10.53328238
103EIF2AK20.53020311
104KSR20.52201149
105PDPK10.51994006
106PDGFRA0.50770112
107PTK2B0.50068894
108DAPK10.48129789
109PDK20.47557131
110PKN20.47432378
111PRKCD0.46373155
112PAK10.46077043
113ZAK0.44433385
114IRAK20.43109542
115EIF2AK10.42474169
116JAK20.42414082
117MAP3K80.41724676
118LATS20.41194356
119LYN0.40850461
120LCK0.39115033
121MAP3K10.38413132
122EGFR0.38184102
123STK160.37098797
124MAP3K50.37065041
125HIPK20.35836615
126ROCK10.35255826
127SYK0.34936515
128NLK0.34531017
129FES0.34192655
130ARAF0.34092158
131YES10.33484151

Predicted pathways (KEGG)

RankGene SetZ-score
1Leishmaniasis_Homo sapiens_hsa051402.66029021
2Graft-versus-host disease_Homo sapiens_hsa053322.24377434
3Pathogenic Escherichia coli infection_Homo sapiens_hsa051302.23874910
4Malaria_Homo sapiens_hsa051442.11826648
5Legionellosis_Homo sapiens_hsa051342.03305339
6Ribosome_Homo sapiens_hsa030101.92175731
7Leukocyte transendothelial migration_Homo sapiens_hsa046701.86062949
8Shigellosis_Homo sapiens_hsa051311.85870880
9Pertussis_Homo sapiens_hsa051331.83499417
10Toll-like receptor signaling pathway_Homo sapiens_hsa046201.81981341
11Bacterial invasion of epithelial cells_Homo sapiens_hsa051001.79097300
12NF-kappa B signaling pathway_Homo sapiens_hsa040641.77884970
13Inflammatory bowel disease (IBD)_Homo sapiens_hsa053211.76797211
14Butirosin and neomycin biosynthesis_Homo sapiens_hsa005241.74584413
15TNF signaling pathway_Homo sapiens_hsa046681.73293183
16ECM-receptor interaction_Homo sapiens_hsa045121.73055707
17Osteoclast differentiation_Homo sapiens_hsa043801.71469938
18Toxoplasmosis_Homo sapiens_hsa051451.70243683
19Hematopoietic cell lineage_Homo sapiens_hsa046401.65869159
20NOD-like receptor signaling pathway_Homo sapiens_hsa046211.64578201
21Cytosolic DNA-sensing pathway_Homo sapiens_hsa046231.64262594
22Salmonella infection_Homo sapiens_hsa051321.62576651
23Tuberculosis_Homo sapiens_hsa051521.58925059
24Phagosome_Homo sapiens_hsa041451.57522557
25Cytokine-cytokine receptor interaction_Homo sapiens_hsa040601.55649071
26Rheumatoid arthritis_Homo sapiens_hsa053231.54708498
27Amoebiasis_Homo sapiens_hsa051461.52963304
28Adherens junction_Homo sapiens_hsa045201.52583165
29Allograft rejection_Homo sapiens_hsa053301.50908172
30Apoptosis_Homo sapiens_hsa042101.49358720
31Viral myocarditis_Homo sapiens_hsa054161.47244860
32AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049331.45527417
33Measles_Homo sapiens_hsa051621.42383656
34Proteoglycans in cancer_Homo sapiens_hsa052051.41556949
35Asthma_Homo sapiens_hsa053101.41376810
36Small cell lung cancer_Homo sapiens_hsa052221.41339169
37Antigen processing and presentation_Homo sapiens_hsa046121.38502752
38Lysosome_Homo sapiens_hsa041421.37595818
39Focal adhesion_Homo sapiens_hsa045101.37352844
40p53 signaling pathway_Homo sapiens_hsa041151.32279275
41Intestinal immune network for IgA production_Homo sapiens_hsa046721.31745383
42Jak-STAT signaling pathway_Homo sapiens_hsa046301.28485952
43Galactose metabolism_Homo sapiens_hsa000521.27210121
44Bladder cancer_Homo sapiens_hsa052191.22464602
45Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005321.20421577
46Autoimmune thyroid disease_Homo sapiens_hsa053201.20160994
47RIG-I-like receptor signaling pathway_Homo sapiens_hsa046221.20024678
48Influenza A_Homo sapiens_hsa051641.16887545
49Chagas disease (American trypanosomiasis)_Homo sapiens_hsa051421.13994962
50Staphylococcus aureus infection_Homo sapiens_hsa051501.09868455
51Other glycan degradation_Homo sapiens_hsa005111.06551919
52Glycosaminoglycan degradation_Homo sapiens_hsa005311.05794992
53Proteasome_Homo sapiens_hsa030501.03275442
54Collecting duct acid secretion_Homo sapiens_hsa049661.01785869
55Herpes simplex infection_Homo sapiens_hsa051681.01523524
56Hepatitis B_Homo sapiens_hsa051611.00986683
57Platelet activation_Homo sapiens_hsa046110.98148684
58Chronic myeloid leukemia_Homo sapiens_hsa052200.94436876
59Regulation of actin cytoskeleton_Homo sapiens_hsa048100.93963497
60Chemokine signaling pathway_Homo sapiens_hsa040620.93295718
61Sulfur metabolism_Homo sapiens_hsa009200.92027243
62Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046660.91364600
63Pancreatic cancer_Homo sapiens_hsa052120.89847797
64Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046500.88873456
65TGF-beta signaling pathway_Homo sapiens_hsa043500.87817613
66Pentose phosphate pathway_Homo sapiens_hsa000300.85399839
67Protein export_Homo sapiens_hsa030600.84029223
68MicroRNAs in cancer_Homo sapiens_hsa052060.83807922
69Hepatitis C_Homo sapiens_hsa051600.81024715
70Acute myeloid leukemia_Homo sapiens_hsa052210.79044240
71Arachidonic acid metabolism_Homo sapiens_hsa005900.78233924
72Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.77990101
73Fructose and mannose metabolism_Homo sapiens_hsa000510.76461487
74Glutathione metabolism_Homo sapiens_hsa004800.75237096
75HTLV-I infection_Homo sapiens_hsa051660.75116114
76Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.74894722
77B cell receptor signaling pathway_Homo sapiens_hsa046620.72833220
78Transcriptional misregulation in cancer_Homo sapiens_hsa052020.68932497
79Sphingolipid metabolism_Homo sapiens_hsa006000.68400530
80African trypanosomiasis_Homo sapiens_hsa051430.68249290
81Hippo signaling pathway_Homo sapiens_hsa043900.67727156
82Prion diseases_Homo sapiens_hsa050200.66114614
83Renal cell carcinoma_Homo sapiens_hsa052110.65775055
84Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.65465614
85Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.63991493
86PI3K-Akt signaling pathway_Homo sapiens_hsa041510.63702537
87Pathways in cancer_Homo sapiens_hsa052000.63650960
88Thyroid cancer_Homo sapiens_hsa052160.63498213
89Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054120.63217394
90Type I diabetes mellitus_Homo sapiens_hsa049400.62620464
91Viral carcinogenesis_Homo sapiens_hsa052030.61052342
92Epstein-Barr virus infection_Homo sapiens_hsa051690.60332698
93VEGF signaling pathway_Homo sapiens_hsa043700.57584978
94Vibrio cholerae infection_Homo sapiens_hsa051100.56780720
95Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.55968264
96Primary immunodeficiency_Homo sapiens_hsa053400.55828651
97Melanoma_Homo sapiens_hsa052180.54690924
98HIF-1 signaling pathway_Homo sapiens_hsa040660.54274222
99Complement and coagulation cascades_Homo sapiens_hsa046100.53888494
100Fc epsilon RI signaling pathway_Homo sapiens_hsa046640.53519428
101T cell receptor signaling pathway_Homo sapiens_hsa046600.52334521
102Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054100.52155534
103Prostate cancer_Homo sapiens_hsa052150.51800990
104Folate biosynthesis_Homo sapiens_hsa007900.50943415
105Tight junction_Homo sapiens_hsa045300.50784500
106Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.50593965
107Mineral absorption_Homo sapiens_hsa049780.49947944
108Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.49707051
109SNARE interactions in vesicular transport_Homo sapiens_hsa041300.49441628
110Neurotrophin signaling pathway_Homo sapiens_hsa047220.49222358
111Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049320.47806939
112Endocytosis_Homo sapiens_hsa041440.45744560
113Rap1 signaling pathway_Homo sapiens_hsa040150.45034862
114Prolactin signaling pathway_Homo sapiens_hsa049170.44388703
115Sphingolipid signaling pathway_Homo sapiens_hsa040710.44280732
116Notch signaling pathway_Homo sapiens_hsa043300.43073819
117Non-small cell lung cancer_Homo sapiens_hsa052230.37343818
118N-Glycan biosynthesis_Homo sapiens_hsa005100.37057040
119Central carbon metabolism in cancer_Homo sapiens_hsa052300.33826610
120Drug metabolism - other enzymes_Homo sapiens_hsa009830.32416654

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