RSL24D1

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: This gene encodes a protein sharing a low level of sequence similarity with human ribosomal protein L24. Although this gene has been referred to as RPL24, L30, and 60S ribosomal protein L30 isolog in the sequence databases, it is distinct from the human genes officially named RPL24 (which itself has been referred to as ribosomal protein L30) and RPL30. The protein encoded by this gene localizes to the nucleolus and is thought to play a role in the biogenesis of the 60S ribosomal subunit. The precise function of this gene is currently unknown. This gene utilizes alternative polyadenylation signals and has multiple pseudogenes. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1SRP-dependent cotranslational protein targeting to membrane (GO:0006614)4.92706380
2cotranslational protein targeting to membrane (GO:0006613)4.86450781
3protein targeting to ER (GO:0045047)4.78875920
4nucleobase biosynthetic process (GO:0046112)4.73161454
5establishment of protein localization to endoplasmic reticulum (GO:0072599)4.68311330
6purine nucleobase biosynthetic process (GO:0009113)4.66890179
7mitotic metaphase plate congression (GO:0007080)4.58977337
8protein localization to endoplasmic reticulum (GO:0070972)4.52929002
9* ribosome biogenesis (GO:0042254)4.48359686
10nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184)4.40476336
11ribosomal small subunit assembly (GO:0000028)4.32977836
12formation of translation preinitiation complex (GO:0001731)4.28276086
13DNA replication initiation (GO:0006270)4.24536516
14establishment of integrated proviral latency (GO:0075713)4.23117982
15maturation of SSU-rRNA (GO:0030490)4.20963908
16DNA strand elongation involved in DNA replication (GO:0006271)4.17906320
17ribosome assembly (GO:0042255)4.17682743
18mitochondrial ATP synthesis coupled proton transport (GO:0042776)4.10043347
19protein localization to kinetochore (GO:0034501)4.09742302
20IMP biosynthetic process (GO:0006188)4.08738233
21viral life cycle (GO:0019058)4.06853508
22DNA replication checkpoint (GO:0000076)4.05099954
23* ribonucleoprotein complex biogenesis (GO:0022613)4.00960989
24cellular protein complex disassembly (GO:0043624)4.00347103
25translation (GO:0006412)3.99421705
26DNA strand elongation (GO:0022616)3.98902616
27telomere maintenance via semi-conservative replication (GO:0032201)3.94308301
28CENP-A containing nucleosome assembly (GO:0034080)3.90671510
29DNA deamination (GO:0045006)3.89134552
30IMP metabolic process (GO:0046040)3.88715433
31metaphase plate congression (GO:0051310)3.84705856
32chromatin remodeling at centromere (GO:0031055)3.81834358
33termination of RNA polymerase III transcription (GO:0006386)3.78301261
34transcription elongation from RNA polymerase III promoter (GO:0006385)3.78301261
35regulation of helicase activity (GO:0051095)3.73385503
36maturation of 5.8S rRNA (GO:0000460)3.67811398
37rRNA processing (GO:0006364)3.67778350
38mitotic nuclear envelope disassembly (GO:0007077)3.66518950
39spliceosomal snRNP assembly (GO:0000387)3.66292618
40telomere maintenance via recombination (GO:0000722)3.61769495
41energy coupled proton transport, down electrochemical gradient (GO:0015985)3.61377415
42ATP synthesis coupled proton transport (GO:0015986)3.61377415
43ribosomal large subunit biogenesis (GO:0042273)3.61195450
44protein localization to chromosome, centromeric region (GO:0071459)3.60064659
45rRNA modification (GO:0000154)3.59952130
46DNA unwinding involved in DNA replication (GO:0006268)3.59513129
47nuclear-transcribed mRNA catabolic process (GO:0000956)3.59439234
48rRNA metabolic process (GO:0016072)3.56768275
49protein complex disassembly (GO:0043241)3.56250280
50establishment of chromosome localization (GO:0051303)3.55576100
51pseudouridine synthesis (GO:0001522)3.54469394
52DNA replication-independent nucleosome organization (GO:0034724)3.54329489
53DNA replication-independent nucleosome assembly (GO:0006336)3.54329489
54macromolecular complex disassembly (GO:0032984)3.53801155
55proteasome assembly (GO:0043248)3.53668323
56regulation of spindle organization (GO:0090224)3.50518301
57DNA replication-dependent nucleosome assembly (GO:0006335)3.49249342
58DNA replication-dependent nucleosome organization (GO:0034723)3.49249342
59nuclear pore organization (GO:0006999)3.44378596
60termination of RNA polymerase I transcription (GO:0006363)3.43845391
61kinetochore organization (GO:0051383)3.43717399
62transcription elongation from RNA polymerase I promoter (GO:0006362)3.43249586
63mitotic recombination (GO:0006312)3.42010183
64transcription from RNA polymerase I promoter (GO:0006360)3.40757873
65tRNA aminoacylation for protein translation (GO:0006418)3.40752800
66mRNA catabolic process (GO:0006402)3.39590006
67regulation of transcription involved in G1/S transition of mitotic cell cycle (GO:0000083)3.39371671
68attachment of spindle microtubules to kinetochore (GO:0008608)3.39009345
69exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay 3.38249609
70ribosomal small subunit biogenesis (GO:0042274)3.37864233
71DNA ligation (GO:0006266)3.37397942
72tRNA aminoacylation (GO:0043039)3.37327524
73amino acid activation (GO:0043038)3.37327524
74anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process (GO:03.36832698
75membrane disassembly (GO:0030397)3.36762531
76nuclear envelope disassembly (GO:0051081)3.36762531
77DNA double-strand break processing (GO:0000729)3.36152064
78oxidative phosphorylation (GO:0006119)3.35381489
797-methylguanosine mRNA capping (GO:0006370)3.33926078
80organelle disassembly (GO:1903008)3.32408902
81nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291)3.31661738
827-methylguanosine RNA capping (GO:0009452)3.30296609
83RNA capping (GO:0036260)3.30296609
84regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051439)3.29570324
85kinetochore assembly (GO:0051382)3.29249179
86negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436)3.28046920
87DNA topological change (GO:0006265)3.26904926
88histone exchange (GO:0043486)3.26200929
89positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051437)3.25176068
90telomere maintenance via telomere lengthening (GO:0010833)3.24452995
91protein targeting to membrane (GO:0006612)3.24294185
92transcription-coupled nucleotide-excision repair (GO:0006283)3.23441085
93transcription initiation from RNA polymerase I promoter (GO:0006361)3.21744377
94ribonucleoprotein complex disassembly (GO:0032988)3.21717627
95RNA catabolic process (GO:0006401)3.21134220
96regulation of double-strand break repair via homologous recombination (GO:0010569)3.20507675
97establishment of viral latency (GO:0019043)3.20025417
98protein K6-linked ubiquitination (GO:0085020)3.19463965
99viral mRNA export from host cell nucleus (GO:0046784)3.17979250
100mitotic sister chromatid segregation (GO:0000070)3.17083306
101translational initiation (GO:0006413)3.15906030
102spindle checkpoint (GO:0031577)3.13455261
103regulation of attachment of spindle microtubules to kinetochore (GO:0051988)3.12914571
104viral transcription (GO:0019083)3.12673045
105translational termination (GO:0006415)3.11497017
106double-strand break repair via nonhomologous end joining (GO:0006303)3.10931231
107non-recombinational repair (GO:0000726)3.10931231
108cullin deneddylation (GO:0010388)3.10730935
109spliceosomal complex assembly (GO:0000245)3.10548229
110nuclear pore complex assembly (GO:0051292)3.10215063
111regulation of nuclear cell cycle DNA replication (GO:0033262)3.09808675
112establishment of protein localization to mitochondrial membrane (GO:0090151)3.09167049
113* cellular component biogenesis (GO:0044085)3.04321140
114DNA catabolic process, exonucleolytic (GO:0000738)3.03418888
115DNA-templated transcription, termination (GO:0006353)3.03294484
116rRNA methylation (GO:0031167)3.01592782
117negative regulation of chromosome segregation (GO:0051985)3.00398828
118cell cycle G1/S phase transition (GO:0044843)3.00273109
119G1/S transition of mitotic cell cycle (GO:0000082)3.00273109
120negative regulation of mitotic sister chromatid separation (GO:2000816)2.99232003
121negative regulation of mitotic sister chromatid segregation (GO:0033048)2.99232003
122negative regulation of mitotic metaphase/anaphase transition (GO:0045841)2.99232003
123negative regulation of sister chromatid segregation (GO:0033046)2.99232003
124somatic hypermutation of immunoglobulin genes (GO:0016446)2.97929599
125somatic diversification of immune receptors via somatic mutation (GO:0002566)2.97929599
126negative regulation of ligase activity (GO:0051352)2.96232870
127negative regulation of ubiquitin-protein transferase activity (GO:0051444)2.96232870
128spindle assembly checkpoint (GO:0071173)2.95889693
129nucleotide-excision repair, DNA gap filling (GO:0006297)2.95606452
130mitotic spindle checkpoint (GO:0071174)2.94714796
131positive regulation of ubiquitin-protein transferase activity (GO:0051443)2.93733401
132mitotic spindle assembly checkpoint (GO:0007094)2.93732808
133folic acid-containing compound biosynthetic process (GO:0009396)2.93221454
134translational elongation (GO:0006414)2.92603611
135negative regulation of metaphase/anaphase transition of cell cycle (GO:1902100)2.90214384
136regulation of chromosome segregation (GO:0051983)2.89702905
137positive regulation of chromosome segregation (GO:0051984)2.89354781
138termination of RNA polymerase II transcription (GO:0006369)2.88923384
139histone mRNA metabolic process (GO:0008334)2.88452651
140regulation of mitotic cell cycle spindle assembly checkpoint (GO:0090266)2.88178720
141regulation of mitotic spindle checkpoint (GO:1903504)2.88178720
142negative regulation of DNA recombination (GO:0045910)2.88063965

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1E2F7_22180533_ChIP-Seq_HELA_Human7.91942637
2MYC_18555785_ChIP-Seq_MESCs_Mouse4.41976074
3E2F4_17652178_ChIP-ChIP_JURKAT_Human3.61379027
4KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human3.51824288
5FOXM1_23109430_ChIP-Seq_U2OS_Human3.49927220
6EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse3.42827969
7EST1_17652178_ChIP-ChIP_JURKAT_Human3.30985343
8GABP_17652178_ChIP-ChIP_JURKAT_Human3.21007658
9FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human3.12008974
10JARID1A_20064375_ChIP-Seq_MESCs_Mouse3.09948918
11ETS1_20019798_ChIP-Seq_JURKAT_Human3.02415812
12MYC_19079543_ChIP-ChIP_MESCs_Mouse3.01727559
13MYC_19030024_ChIP-ChIP_MESCs_Mouse2.97240696
14MYC_18358816_ChIP-ChIP_MESCs_Mouse2.89031869
15E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse2.88570254
16CREB1_15753290_ChIP-ChIP_HEK293T_Human2.87564161
17HCFC1_20581084_ChIP-Seq_MESCs_Mouse2.58045833
18CHD1_19587682_ChIP-ChIP_MESCs_Mouse2.44969800
19NELFA_20434984_ChIP-Seq_ESCs_Mouse2.44705211
20* VDR_23849224_ChIP-Seq_CD4+_Human2.43828152
21NOTCH1_17114293_ChIP-ChIP_T-ALL_Human2.32128407
22XRN2_22483619_ChIP-Seq_HELA_Human2.32005315
23MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse2.24302082
24HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human2.09839474
25FOXP3_21729870_ChIP-Seq_TREG_Human2.07283651
26E2F1_18555785_ChIP-Seq_MESCs_Mouse2.04118474
27MYBL2_22936984_ChIP-ChIP_MESCs_Mouse2.03387753
28ELF1_17652178_ChIP-ChIP_JURKAT_Human1.95339074
29AR_21909140_ChIP-Seq_LNCAP_Human1.94598238
30DCP1A_22483619_ChIP-Seq_HELA_Human1.93484826
31GABP_19822575_ChIP-Seq_HepG2_Human1.92448095
32MYCN_18555785_ChIP-Seq_MESCs_Mouse1.90273934
33ELK1_19687146_ChIP-ChIP_HELA_Human1.89927983
34PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse1.87552497
35POU5F1_18555785_ChIP-Seq_MESCs_Mouse1.86314037
36TTF2_22483619_ChIP-Seq_HELA_Human1.85207967
37KDM5B_21448134_ChIP-Seq_MESCs_Mouse1.84931771
38THAP11_20581084_ChIP-Seq_MESCs_Mouse1.84650073
39NANOG_18555785_ChIP-Seq_MESCs_Mouse1.83499268
40E2F1_21310950_ChIP-Seq_MCF-7_Human1.80824694
41* SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse1.76328030
42FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse1.75761803
43YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.75341954
44YY1_21170310_ChIP-Seq_MESCs_Mouse1.74937014
45EWS_26573619_Chip-Seq_HEK293_Human1.66901076
46HOXB4_20404135_ChIP-ChIP_EML_Mouse1.63230649
47SOX9_22984422_ChIP-ChIP_TESTIS_Rat1.61019468
48FUS_26573619_Chip-Seq_HEK293_Human1.57031040
49EGR1_19374776_ChIP-ChIP_THP-1_Human1.56985473
50ZFP42_18358816_ChIP-ChIP_MESCs_Mouse1.56397221
51MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.55892019
52SRF_21415370_ChIP-Seq_HL-1_Mouse1.54641129
53CIITA_25753668_ChIP-Seq_RAJI_Human1.53569611
54TAL1_20887958_ChIP-Seq_HPC-7_Mouse1.51621572
55ZFX_18555785_ChIP-Seq_MESCs_Mouse1.48599537
56KDM5A_27292631_Chip-Seq_BREAST_Human1.42841121
57CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human1.38342180
58POU5F1_18358816_ChIP-ChIP_MESCs_Mouse1.37845071
59POU5F1_18700969_ChIP-ChIP_MESCs_Mouse1.34039723
60IGF1R_20145208_ChIP-Seq_DFB_Human1.34001108
61NOTCH1_21737748_ChIP-Seq_TLL_Human1.33593120
62* SFPI1_20887958_ChIP-Seq_HPC-7_Mouse1.33448259
63TP63_19390658_ChIP-ChIP_HaCaT_Human1.32644325
64SMAD1_18555785_ChIP-Seq_MESCs_Mouse1.30097951
65STAT3_1855785_ChIP-Seq_MESCs_Mouse1.27726850
66ASXL1_24218140_ChIP-Seq_BMDM_Mouse1.27399149
67* FLI1_20887958_ChIP-Seq_HPC-7_Mouse1.26620114
68POU3F2_20337985_ChIP-ChIP_501MEL_Human1.26520251
69HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse1.26263379
70ERG_20887958_ChIP-Seq_HPC-7_Mouse1.24537900
71PADI4_21655091_ChIP-ChIP_MCF-7_Human1.23850217
72MYC_22102868_ChIP-Seq_BL_Human1.23832301
73PRDM5_23873026_ChIP-Seq_MEFs_Mouse1.20805725
74CCND1_20090754_ChIP-ChIP_RETINA_Mouse1.18881597
75KLF4_18555785_ChIP-Seq_MESCs_Mouse1.14642107
76ASH2L_23239880_ChIP-Seq_MESCs_Mouse1.14533707
77SOX2_18555785_ChIP-Seq_MESCs_Mouse1.14035366
78PDX1_19855005_ChIP-ChIP_MIN6_Mouse1.13599619
79SOX2_16153702_ChIP-ChIP_HESCs_Human1.12104721
80NANOG_16153702_ChIP-ChIP_HESCs_Human1.10818311
81TAF15_26573619_Chip-Seq_HEK293_Human1.10355824
82TFEB_21752829_ChIP-Seq_HELA_Human1.08042709
83FLI1_27457419_Chip-Seq_LIVER_Mouse1.07626419
84SPI1_22096565_ChIP-ChIP_GC-B_Mouse1.07222256
85SOX2_19030024_ChIP-ChIP_MESCs_Mouse1.06327515
86MYC_18940864_ChIP-ChIP_HL60_Human1.05507138
87E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human1.05497622
88ELK1_22589737_ChIP-Seq_MCF10A_Human1.03361718
89BCL3_23251550_ChIP-Seq_MUSCLE_Mouse1.02929651
90POU5F1_16153702_ChIP-ChIP_HESCs_Human1.01703785
91HNF4A_19761587_ChIP-ChIP_CACO-2_Human1.01223510
92KLF4_19030024_ChIP-ChIP_MESCs_Mouse0.99999056
93RBPJ_22232070_ChIP-Seq_NCS_Mouse0.96642115
94VDR_22108803_ChIP-Seq_LS180_Human0.96135434
95NACC1_18358816_ChIP-ChIP_MESCs_Mouse0.95459717
96CREM_20920259_ChIP-Seq_GC1-SPG_Mouse0.93122685
97RCOR1_19997604_ChIP-ChIP_NEURONS_Mouse0.93108185
98* SPI1_23547873_ChIP-Seq_NB4_Human0.92811261
99CNOT3_19339689_ChIP-ChIP_MESCs_Mouse0.92634858
100SOX17_20123909_ChIP-Seq_XEN_Mouse0.92217119
101* CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat0.90816772
102DACH1_20351289_ChIP-Seq_MDA-MB-231_Human0.90585684
103ZNF274_21170338_ChIP-Seq_K562_Hela0.89634424
104TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat0.89527855
105KLF5_18264089_ChIP-ChIP_MESCs_Mouse0.89171889
106KLF4_18264089_ChIP-ChIP_MESCs_Mouse0.89171889
107KLF2_18264089_ChIP-ChIP_MESCs_Mouse0.89171889
108* GFI1B_20887958_ChIP-Seq_HPC-7_Mouse0.87095733
109KLF4_18358816_ChIP-ChIP_MESCs_Mouse0.86139354
110NANOG_18700969_ChIP-ChIP_MESCs_Mouse0.86003747
111NANOG_18358816_ChIP-ChIP_MESCs_Mouse0.85432621
112ELF5_23300383_ChIP-Seq_T47D_Human0.84167820
113SALL1_21062744_ChIP-ChIP_HESCs_Human0.82772134
114IRF1_19129219_ChIP-ChIP_H3396_Human0.82757697
115NANOG_21062744_ChIP-ChIP_HESCs_Human0.82242375
116CREB1_20920259_ChIP-Seq_GC1-SPG_Mouse0.79807594
117CUX1_19635798_ChIP-ChIP_MULTIPLE_HUMAN_CANCER_TYPES_Human0.79723318
118CEBPB_23403033_ChIP-Seq_LIVER_Mouse0.78931694
119TCF3_18692474_ChIP-Seq_MEFs_Mouse0.78173176
120FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse0.74182237

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0003693_abnormal_embryo_hatching5.69739269
2MP0010094_abnormal_chromosome_stability4.64357242
3MP0004957_abnormal_blastocyst_morpholog4.55699572
4MP0003111_abnormal_nucleus_morphology4.50547130
5MP0003077_abnormal_cell_cycle4.09897983
6MP0008057_abnormal_DNA_replication3.97832778
7MP0008058_abnormal_DNA_repair3.81390486
8MP0008007_abnormal_cellular_replicative3.25133564
9MP0003718_maternal_effect2.50964545
10MP0008932_abnormal_embryonic_tissue2.50375498
11MP0003123_paternal_imprinting2.46184111
12MP0009379_abnormal_foot_pigmentation2.45600000
13MP0003786_premature_aging2.42635000
14MP0002396_abnormal_hematopoietic_system2.40025240
15MP0008877_abnormal_DNA_methylation2.36712810
16MP0001730_embryonic_growth_arrest2.34657874
17MP0000350_abnormal_cell_proliferation2.20757076
18MP0001529_abnormal_vocalization2.07121025
19MP0010307_abnormal_tumor_latency1.93660144
20MP0006292_abnormal_olfactory_placode1.91069692
21MP0004147_increased_porphyrin_level1.87704247
22MP0006072_abnormal_retinal_apoptosis1.79943003
23MP0001672_abnormal_embryogenesis/_devel1.79121068
24MP0005380_embryogenesis_phenotype1.79121068
25MP0004808_abnormal_hematopoietic_stem1.77476071
26MP0001697_abnormal_embryo_size1.65053715
27MP0000490_abnormal_crypts_of1.62073006
28MP0003984_embryonic_growth_retardation1.58527289
29MP0005084_abnormal_gallbladder_morpholo1.58124415
30MP0000313_abnormal_cell_death1.54322741
31MP0002088_abnormal_embryonic_growth/wei1.53763676
32MP0002080_prenatal_lethality1.53750605
33MP0010352_gastrointestinal_tract_polyps1.53259520
34MP0002102_abnormal_ear_morphology1.50163920
35MP0001188_hyperpigmentation1.48682132
36MP0009333_abnormal_splenocyte_physiolog1.43707689
37MP0002019_abnormal_tumor_incidence1.42727580
38MP0002210_abnormal_sex_determination1.40518028
39MP0002085_abnormal_embryonic_tissue1.40300651
40MP0003567_abnormal_fetal_cardiomyocyte1.39392184
41MP0003315_abnormal_perineum_morphology1.31588088
42MP0002084_abnormal_developmental_patter1.29436659
43MP0002877_abnormal_melanocyte_morpholog1.28361039
44MP0005397_hematopoietic_system_phenotyp1.27712627
45MP0001545_abnormal_hematopoietic_system1.27712627
46MP0002086_abnormal_extraembryonic_tissu1.26676170
47MP0002938_white_spotting1.21725224
48MP0003121_genomic_imprinting1.20733304
49MP0001145_abnormal_male_reproductive1.19945761
50MP0001293_anophthalmia1.18458726
51MP0004197_abnormal_fetal_growth/weight/1.18405162
52MP0002160_abnormal_reproductive_system1.17080094
53MP0003186_abnormal_redox_activity1.13697147
54MP0002751_abnormal_autonomic_nervous1.13555269
55MP0003763_abnormal_thymus_physiology1.13329781
56MP0002398_abnormal_bone_marrow1.11056076
57MP0003890_abnormal_embryonic-extraembry1.07686964
58MP0003941_abnormal_skin_development1.07153015
59MP0001119_abnormal_female_reproductive1.07090684
60MP0001929_abnormal_gametogenesis1.06913642
61MP0000653_abnormal_sex_gland1.05790813
62MP0002722_abnormal_immune_system1.04736993
63MP0000689_abnormal_spleen_morphology1.04441446
64MP0000703_abnormal_thymus_morphology1.02145974
65MP0010030_abnormal_orbit_morphology1.01980930
66MP0005389_reproductive_system_phenotype0.98994477
67MP0005499_abnormal_olfactory_system0.97218641
68MP0005394_taste/olfaction_phenotype0.97218641
69MP0002233_abnormal_nose_morphology0.90376687
70MP0000358_abnormal_cell_content/0.90315337
71MP0000372_irregular_coat_pigmentation0.89837519
72MP0002234_abnormal_pharynx_morphology0.89603880
73MP0003806_abnormal_nucleotide_metabolis0.89539740
74MP0001764_abnormal_homeostasis0.88817510
75MP0005408_hypopigmentation0.88549537
76MP0000858_altered_metastatic_potential0.87348359
77MP0005645_abnormal_hypothalamus_physiol0.86542197
78MP0002132_abnormal_respiratory_system0.86195350
79MP0002429_abnormal_blood_cell0.85766501
80MP0009697_abnormal_copulation0.84569566
81MP0002697_abnormal_eye_size0.82723878
82MP0000647_abnormal_sebaceous_gland0.82717260
83MP0002653_abnormal_ependyma_morphology0.82248417
84MP0009703_decreased_birth_body0.81891190
85MP0006035_abnormal_mitochondrial_morpho0.81624232
86MP0003221_abnormal_cardiomyocyte_apopto0.81365098
87MP0005384_cellular_phenotype0.80650018
88MP0004782_abnormal_surfactant_physiolog0.79974456
89MP0000631_abnormal_neuroendocrine_gland0.79727473
90MP0002006_tumorigenesis0.77630752
91MP0005220_abnormal_exocrine_pancreas0.77049416
92MP0000716_abnormal_immune_system0.76572692
93MP0006036_abnormal_mitochondrial_physio0.76545468
94MP0005621_abnormal_cell_physiology0.74478891
95MP0001727_abnormal_embryo_implantation0.73483224
96MP0001919_abnormal_reproductive_system0.73212610
97MP0001835_abnormal_antigen_presentation0.73165706
98MP0003119_abnormal_digestive_system0.72569341
99MP0005671_abnormal_response_to0.72521626
100MP0005253_abnormal_eye_physiology0.72050797
101MP0008260_abnormal_autophagy0.71655636
102MP0001286_abnormal_eye_development0.70281750
103MP0003937_abnormal_limbs/digits/tail_de0.70232916
104MP0008995_early_reproductive_senescence0.69821784
105MP0009053_abnormal_anal_canal0.68548709
106MP0002009_preneoplasia0.67048507
107MP0002111_abnormal_tail_morphology0.66386978
108MP0003698_abnormal_male_reproductive0.65941436
109MP0005395_other_phenotype0.65338992
110MP0001853_heart_inflammation0.64037073
111MP0001881_abnormal_mammary_gland0.63388521
112MP0002166_altered_tumor_susceptibility0.63087144
113MP0004133_heterotaxia0.62949000
114MP0005076_abnormal_cell_differentiation0.61314459
115MP0003699_abnormal_female_reproductive0.61309925
116MP0005391_vision/eye_phenotype0.60414583
117MP0004215_abnormal_myocardial_fiber0.60360308
118MP0005501_abnormal_skin_physiology0.60286900
119MP0005075_abnormal_melanosome_morpholog0.59986683
120MP0001340_abnormal_eyelid_morphology0.59968332
121MP0002090_abnormal_vision0.58426134
122MP0002420_abnormal_adaptive_immunity0.57689453
123MP0003136_yellow_coat_color0.57445929
124MP0001819_abnormal_immune_cell0.57052964
125MP0000428_abnormal_craniofacial_morphol0.57007371
126MP0001177_atelectasis0.56932685
127MP0008789_abnormal_olfactory_epithelium0.56345430
128MP0002095_abnormal_skin_pigmentation0.56320910
129MP0001800_abnormal_humoral_immune0.56178757
130MP0001915_intracranial_hemorrhage0.55982866
131MP0001849_ear_inflammation0.55960727
132MP0002277_abnormal_respiratory_mucosa0.55526897
133MP0009672_abnormal_birth_weight0.55475216
134MP0003448_altered_tumor_morphology0.55196790
135MP0003943_abnormal_hepatobiliary_system0.54120123

Predicted human phenotypes

RankGene SetZ-score
1Birth length less than 3rd percentile (HP:0003561)5.29078258
2Breast hypoplasia (HP:0003187)4.29866075
3Increased hepatocellular lipid droplets (HP:0006565)4.12055074
4Abnormality of cells of the erythroid lineage (HP:0012130)4.05458507
5Abnormal number of erythroid precursors (HP:0012131)3.92527079
6Carpal bone hypoplasia (HP:0001498)3.81593887
7Lipid accumulation in hepatocytes (HP:0006561)3.61718885
8Chromsome breakage (HP:0040012)3.60473365
9Chromosomal breakage induced by crosslinking agents (HP:0003221)3.58373932
10Acute necrotizing encephalopathy (HP:0006965)3.52846867
11Abnormality of the anterior horn cell (HP:0006802)3.51236609
12Degeneration of anterior horn cells (HP:0002398)3.51236609
13Patellar aplasia (HP:0006443)3.44682838
14Oral leukoplakia (HP:0002745)3.43349487
15Reticulocytopenia (HP:0001896)3.34264069
16Aplasia/Hypoplasia of the patella (HP:0006498)3.30503315
17Acute encephalopathy (HP:0006846)3.21047143
18Aplastic anemia (HP:0001915)3.20134801
19Cerebral hypomyelination (HP:0006808)3.15177951
20Abnormal mitochondria in muscle tissue (HP:0008316)3.13496808
21Impulsivity (HP:0100710)3.11259871
22Meckel diverticulum (HP:0002245)3.10825907
23Abnormality of the preputium (HP:0100587)3.08067531
24Progressive macrocephaly (HP:0004481)3.05832828
25Increased CSF lactate (HP:0002490)3.04300545
26Rough bone trabeculation (HP:0100670)3.03900231
27Abnormality of chromosome stability (HP:0003220)3.00450126
28Selective tooth agenesis (HP:0001592)3.00392762
29Mitochondrial inheritance (HP:0001427)2.94529903
30Abnormality of the ileum (HP:0001549)2.94163289
31Microvesicular hepatic steatosis (HP:0001414)2.89537336
32Colon cancer (HP:0003003)2.88077777
33Medulloblastoma (HP:0002885)2.76185575
34Aplasia/Hypoplasia of the uvula (HP:0010293)2.73724731
35Abnormality of the labia minora (HP:0012880)2.71899340
36Myelodysplasia (HP:0002863)2.71842321
37Stenosis of the external auditory canal (HP:0000402)2.71068262
38Microretrognathia (HP:0000308)2.68536672
39Absent thumb (HP:0009777)2.67527286
40Agnosia (HP:0010524)2.66616939
41Bone marrow hypocellularity (HP:0005528)2.65792077
42Abnormality of methionine metabolism (HP:0010901)2.63889843
43Cerebral edema (HP:0002181)2.62627701
44Aplasia/Hypoplasia involving the carpal bones (HP:0006502)2.57267586
45Premature graying of hair (HP:0002216)2.54806727
46Supernumerary spleens (HP:0009799)2.54646556
47Irregular epiphyses (HP:0010582)2.52781224
48Absent radius (HP:0003974)2.49991159
49Abnormal lung lobation (HP:0002101)2.49319958
50Small intestinal stenosis (HP:0012848)2.48737379
51Duodenal stenosis (HP:0100867)2.48737379
52Cortical dysplasia (HP:0002539)2.46534983
53Short middle phalanx of the 5th finger (HP:0004220)2.46244800
54Thrombocytosis (HP:0001894)2.45180342
55Multiple enchondromatosis (HP:0005701)2.43601372
5611 pairs of ribs (HP:0000878)2.43408820
57CNS hypomyelination (HP:0003429)2.39170029
58Renal Fanconi syndrome (HP:0001994)2.39004794
593-Methylglutaconic aciduria (HP:0003535)2.38870263
60Decreased activity of mitochondrial respiratory chain (HP:0008972)2.35135048
61Abnormal activity of mitochondrial respiratory chain (HP:0011922)2.35135048
62Hepatocellular necrosis (HP:0001404)2.35091374
63Increased intramyocellular lipid droplets (HP:0012240)2.33180521
64Embryonal renal neoplasm (HP:0011794)2.32642002
65Neoplasm of the pancreas (HP:0002894)2.31003775
66Sloping forehead (HP:0000340)2.30487775
67Macrocytic anemia (HP:0001972)2.30396800
68Premature ovarian failure (HP:0008209)2.29521739
69Aplasia involving forearm bones (HP:0009822)2.29084691
70Absent forearm bone (HP:0003953)2.29084691
71Increased serum pyruvate (HP:0003542)2.27978230
72Trismus (HP:0000211)2.27213275
73Type I transferrin isoform profile (HP:0003642)2.26347553
74Methylmalonic acidemia (HP:0002912)2.25038655
75Abnormality of aspartate family amino acid metabolism (HP:0010899)2.23861498
76Lactic acidosis (HP:0003128)2.23613395
77Progressive muscle weakness (HP:0003323)2.22507826
78Abnormality of glycolysis (HP:0004366)2.22377186
79Volvulus (HP:0002580)2.22346260
80Abnormality of serum amino acid levels (HP:0003112)2.21490178
81Hepatic necrosis (HP:0002605)2.21273011
82Cleft eyelid (HP:0000625)2.20471524
83Glossoptosis (HP:0000162)2.19984028
84Rhabdomyosarcoma (HP:0002859)2.19859593
85Ependymoma (HP:0002888)2.18835801
86Pallor (HP:0000980)2.18216638
87Abnormal trabecular bone morphology (HP:0100671)2.17523322
88Type 2 muscle fiber atrophy (HP:0003554)2.16260611
89Muscle fiber atrophy (HP:0100295)2.14819966
90Horseshoe kidney (HP:0000085)2.11920391
91Exertional dyspnea (HP:0002875)2.09647305
92Cellular immunodeficiency (HP:0005374)2.08759593
93Clubbing of toes (HP:0100760)2.07441985
94Abnormal spermatogenesis (HP:0008669)2.07091712
95Tracheoesophageal fistula (HP:0002575)2.07078922
96Respiratory difficulties (HP:0002880)2.06475389
97Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688)2.05155103
98Abnormality of alanine metabolism (HP:0010916)2.04276332
99Abnormality of pyruvate family amino acid metabolism (HP:0010915)2.04276332
100Abnormal number of incisors (HP:0011064)2.03885633
101Abnormality of the duodenum (HP:0002246)2.03268022
102Atrophy/Degeneration involving motor neurons (HP:0007373)2.00828307
103Hypoplasia of the capital femoral epiphysis (HP:0003090)1.98453524
104Amaurosis fugax (HP:0100576)1.98375087
105Leukodystrophy (HP:0002415)1.96932363
106Triphalangeal thumb (HP:0001199)1.95672293
107Exercise intolerance (HP:0003546)1.94960754
108Secondary amenorrhea (HP:0000869)1.90483776
109Megaloblastic anemia (HP:0001889)1.90476821
110Muscle abnormality related to mitochondrial dysfunction (HP:0003800)1.90397115
111Lymphoma (HP:0002665)1.88942417
112Sparse eyelashes (HP:0000653)1.88151837
113Short thumb (HP:0009778)1.87885917
114Atresia of the external auditory canal (HP:0000413)1.87023208
115Aplasia/Hypoplasia of the middle phalanx of the 5th finger (HP:0009161)1.86579036
116Squamous cell carcinoma (HP:0002860)1.85612983
117Reduced antithrombin III activity (HP:0001976)1.85593790
118Pancreatic islet-cell hyperplasia (HP:0004510)1.85267402
119Abnormality of the pons (HP:0007361)1.85084019
120Pancytopenia (HP:0001876)1.83797950
121Hypoplasia of the radius (HP:0002984)1.81589281
122Facial cleft (HP:0002006)1.80797614
123Ectopic kidney (HP:0000086)1.80582637
124Homocystinuria (HP:0002156)1.80314613
125Abnormality of homocysteine metabolism (HP:0010919)1.80314613
126Abnormal protein N-linked glycosylation (HP:0012347)1.79256014
127Abnormal protein glycosylation (HP:0012346)1.79256014
128Abnormal glycosylation (HP:0012345)1.79256014
129Abnormal isoelectric focusing of serum transferrin (HP:0003160)1.79256014
130Basal cell carcinoma (HP:0002671)1.79195804
131IgG deficiency (HP:0004315)1.78924290
132Increased serum lactate (HP:0002151)1.77950821
133Acute myeloid leukemia (HP:0004808)1.77497057
134IgM deficiency (HP:0002850)1.77367664
135Aplasia/Hypoplasia of the sacrum (HP:0008517)1.77270149
136Aplasia/Hypoplasia of the capital femoral epiphysis (HP:0005003)1.76071082
137Absent epiphyses (HP:0010577)1.76071082
138Depressed nasal ridge (HP:0000457)1.75780157
139Tongue fasciculations (HP:0001308)1.75748261
140Entropion (HP:0000621)1.75695702
141Hypoplasia of the pons (HP:0012110)1.75069494
142Aplasia/Hypoplasia of the phalanges of the 5th finger (HP:0009376)1.74937199
143Optic nerve coloboma (HP:0000588)1.74098432
144Congenital, generalized hypertrichosis (HP:0004540)1.74001524
145Aplasia/Hypoplasia of the sternum (HP:0006714)1.73438720
146Nephroblastoma (Wilms tumor) (HP:0002667)1.73318954
147Respiratory failure (HP:0002878)1.71304386
148Dyschromatopsia (HP:0007641)1.70641436
149Increased muscle lipid content (HP:0009058)1.70611445
150Postnatal microcephaly (HP:0005484)1.70252090
151Rectovaginal fistula (HP:0000143)1.69974419
152Rectal fistula (HP:0100590)1.69974419
153Abnormality of the middle phalanx of the 5th finger (HP:0004219)1.69661698
154Facial hemangioma (HP:0000329)1.68544019
155Neoplasm of the colon (HP:0100273)1.67573315
156Abnormality of reticulocytes (HP:0004312)1.66691058
157Spinal muscular atrophy (HP:0007269)1.66191437
158Personality changes (HP:0000751)1.65262441
159Hyperalaninemia (HP:0003348)1.64648322
160Optic disc pallor (HP:0000543)1.64173810
161Abnormality of the septum pellucidum (HP:0007375)1.62905576

Predicted kinase interactions (KEA)

RankGene SetZ-score
1BUB14.93918800
2WEE14.20599438
3EIF2AK13.50989817
4CDC73.48991806
5SRPK12.79468238
6EIF2AK32.73366099
7TSSK62.69533545
8PLK42.58051082
9ACVR1B2.52241952
10MKNK12.49327674
11BRSK22.46335910
12NEK22.36519943
13NME22.22890309
14STK162.11142057
15VRK22.11011994
16CDK192.09290370
17TAF12.04315589
18NEK12.01234653
19PLK12.01082707
20MKNK21.96683966
21TTK1.95515197
22VRK11.95132258
23PLK31.91731076
24MAP3K121.79102096
25TRIM281.76993977
26CCNB11.75065984
27TESK21.71659268
28MAP4K21.71145159
29ZAK1.62444591
30AURKB1.60079901
31CDK71.55196772
32ATR1.51807169
33BCR1.48619713
34DYRK31.46990748
35NUAK11.46533057
36RPS6KB21.42724115
37BRSK11.37078554
38EIF2AK21.36543569
39RPS6KA41.33326208
40CHEK21.32854212
41PASK1.27896201
42PIM21.17488514
43TLK11.15960023
44PIM11.15848511
45AURKA1.13302435
46EPHA21.10862924
47CDK41.08896028
48AKT31.08753564
49MAP3K41.08002864
50TGFBR11.07159895
51CHEK11.04727314
52BMPR21.03079205
53MAP3K81.02419690
54STK40.95058945
55STK38L0.94465786
56STK100.91761923
57WNK30.90410777
58CDK120.89584286
59CLK10.88986830
60PAK40.80924553
61CDK20.75008373
62CSNK2A10.70464015
63TNIK0.70138527
64MAP3K100.70072090
65STK240.69838099
66ATM0.69610474
67CDK80.69275196
68CSNK2A20.67894529
69STK30.67364630
70CSNK1G10.67222331
71CDK30.66529855
72MST40.65308384
73IRAK40.61254632
74BRAF0.60497306
75CSNK1G30.60039363
76ALK0.59678335
77PLK20.57967031
78OXSR10.57205223
79RPS6KA50.56905709
80IRAK30.56689885
81BMPR1B0.56478192
82NME10.56042668
83MAP2K30.55265613
84MAP4K10.55233747
85MAP2K70.54861094
86PRKCI0.54190937
87MELK0.53737836
88ERBB40.53720177
89PAK10.53370968
90CDK10.53055599
91EEF2K0.52443923
92CSNK1A1L0.51943843
93FLT30.51744092
94CSNK1G20.51558436
95FGFR10.50483551
96STK390.49419851
97TEC0.48980275
98MAPKAPK30.46746324
99TAOK20.44233470
100IKBKB0.43988855
101BRD40.43745700
102TXK0.41312466
103YES10.40811470
104SCYL20.39198367
105KDR0.38424907
106MARK30.38059186
107PDK40.36674158
108PDK30.36674158
109RAF10.35947217
110CDK60.35946559
111TESK10.35169922
112DYRK20.35073325
113RPS6KB10.34869646
114DAPK10.34554921
115BCKDK0.34376122
116CHUK0.32601215
117PNCK0.32131612
118KSR10.32131443
119BTK0.32090848
120MAP3K30.31673140
121PBK0.31076368
122LATS20.30563080
123MAP3K110.30075545
124MAPKAPK50.29905941
125PINK10.29409799
126CDK140.29037658
127LRRK20.25851745
128PDK20.25320994
129SIK30.24865511
130NEK60.24749044
131CSNK1E0.23962377
132MAP3K50.22497143
133ERBB30.22132507
134AKT20.21833937

Predicted pathways (KEGG)

RankGene SetZ-score
1DNA replication_Homo sapiens_hsa030304.50274800
2Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030084.34471531
3RNA polymerase_Homo sapiens_hsa030204.14905726
4Mismatch repair_Homo sapiens_hsa034303.82493188
5Proteasome_Homo sapiens_hsa030503.68043133
6Spliceosome_Homo sapiens_hsa030403.35837543
7* Ribosome_Homo sapiens_hsa030103.29902554
8RNA transport_Homo sapiens_hsa030133.28729098
9Homologous recombination_Homo sapiens_hsa034402.80481822
10Base excision repair_Homo sapiens_hsa034102.79725357
11Nucleotide excision repair_Homo sapiens_hsa034202.74296658
12Pyrimidine metabolism_Homo sapiens_hsa002402.67781014
13Cell cycle_Homo sapiens_hsa041102.65256233
14Basal transcription factors_Homo sapiens_hsa030222.38842792
15One carbon pool by folate_Homo sapiens_hsa006702.24090743
16Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009702.16243565
17Fanconi anemia pathway_Homo sapiens_hsa034602.13856877
18RNA degradation_Homo sapiens_hsa030182.11290488
19Non-homologous end-joining_Homo sapiens_hsa034501.83572695
20mRNA surveillance pathway_Homo sapiens_hsa030151.78308913
21Cytosolic DNA-sensing pathway_Homo sapiens_hsa046231.68165038
22p53 signaling pathway_Homo sapiens_hsa041151.63534602
23Purine metabolism_Homo sapiens_hsa002301.59878180
24Vitamin B6 metabolism_Homo sapiens_hsa007501.51254772
25Propanoate metabolism_Homo sapiens_hsa006401.38838344
26Alzheimers disease_Homo sapiens_hsa050101.37934064
27Epstein-Barr virus infection_Homo sapiens_hsa051691.36784551
28Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049321.13861803
29Systemic lupus erythematosus_Homo sapiens_hsa053221.07328122
30Pyruvate metabolism_Homo sapiens_hsa006201.04793692
31Herpes simplex infection_Homo sapiens_hsa051681.03228360
32Folate biosynthesis_Homo sapiens_hsa007901.01142312
33Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005201.00586913
34Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.96024083
35Oocyte meiosis_Homo sapiens_hsa041140.93384161
36Synthesis and degradation of ketone bodies_Homo sapiens_hsa000720.92625304
37Viral carcinogenesis_Homo sapiens_hsa052030.90004005
38Steroid biosynthesis_Homo sapiens_hsa001000.89730467
39Antigen processing and presentation_Homo sapiens_hsa046120.87071991
40Pentose phosphate pathway_Homo sapiens_hsa000300.81847925
41Cysteine and methionine metabolism_Homo sapiens_hsa002700.81403424
42Legionellosis_Homo sapiens_hsa051340.78082968
43Fatty acid elongation_Homo sapiens_hsa000620.74895475
44Huntingtons disease_Homo sapiens_hsa050160.72023101
45Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.71667215
46Cardiac muscle contraction_Homo sapiens_hsa042600.71158393
47Biosynthesis of amino acids_Homo sapiens_hsa012300.68255638
48Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.65779818
49Drug metabolism - other enzymes_Homo sapiens_hsa009830.64551364
50Selenocompound metabolism_Homo sapiens_hsa004500.63361695
51Valine, leucine and isoleucine degradation_Homo sapiens_hsa002800.63068715
52HTLV-I infection_Homo sapiens_hsa051660.62547666
53Protein export_Homo sapiens_hsa030600.61134055
54Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.57391057
55Primary immunodeficiency_Homo sapiens_hsa053400.56971752
56Sulfur relay system_Homo sapiens_hsa041220.52277701
57Thyroid cancer_Homo sapiens_hsa052160.50939982
58Parkinsons disease_Homo sapiens_hsa050120.50616275
59Measles_Homo sapiens_hsa051620.49648221
60Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.48268642
61Apoptosis_Homo sapiens_hsa042100.44357074
62Allograft rejection_Homo sapiens_hsa053300.44301360
63Transcriptional misregulation in cancer_Homo sapiens_hsa052020.44005394
64MicroRNAs in cancer_Homo sapiens_hsa052060.41560673
65NF-kappa B signaling pathway_Homo sapiens_hsa040640.40984450
66Glutathione metabolism_Homo sapiens_hsa004800.40843275
67Fructose and mannose metabolism_Homo sapiens_hsa000510.38970686
68Cyanoamino acid metabolism_Homo sapiens_hsa004600.38189838
69Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.36794608
70Influenza A_Homo sapiens_hsa051640.33959965
71Intestinal immune network for IgA production_Homo sapiens_hsa046720.32817589
72N-Glycan biosynthesis_Homo sapiens_hsa005100.32305271
73NOD-like receptor signaling pathway_Homo sapiens_hsa046210.32237197
74Peroxisome_Homo sapiens_hsa041460.31982043
75Carbon metabolism_Homo sapiens_hsa012000.31818812
76Citrate cycle (TCA cycle)_Homo sapiens_hsa000200.31264812
77Regulation of autophagy_Homo sapiens_hsa041400.31022377
78Graft-versus-host disease_Homo sapiens_hsa053320.31019349
79Small cell lung cancer_Homo sapiens_hsa052220.30344570
80Alcoholism_Homo sapiens_hsa050340.29120045
81TGF-beta signaling pathway_Homo sapiens_hsa043500.29063429
82Hepatitis B_Homo sapiens_hsa051610.28120509
83Oxidative phosphorylation_Homo sapiens_hsa001900.26862671
84Shigellosis_Homo sapiens_hsa051310.25969947
85Metabolic pathways_Homo sapiens_hsa011000.25347575
86Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.25203171
87Colorectal cancer_Homo sapiens_hsa052100.24945565
88HIF-1 signaling pathway_Homo sapiens_hsa040660.24100211
89Arachidonic acid metabolism_Homo sapiens_hsa005900.23491770
90Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006300.23057583
91Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.23005099
92Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.22329355
93RIG-I-like receptor signaling pathway_Homo sapiens_hsa046220.22246610
94Butanoate metabolism_Homo sapiens_hsa006500.20813336
95Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.20601936
96Asthma_Homo sapiens_hsa053100.20553208
97Notch signaling pathway_Homo sapiens_hsa043300.19613529
98Hippo signaling pathway_Homo sapiens_hsa043900.17956651
99Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.17916222
100Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001300.17869421
101Pentose and glucuronate interconversions_Homo sapiens_hsa000400.17461238
102Hematopoietic cell lineage_Homo sapiens_hsa046400.16714030
103Type I diabetes mellitus_Homo sapiens_hsa049400.16654833
104Galactose metabolism_Homo sapiens_hsa000520.16556989
105Phototransduction_Homo sapiens_hsa047440.16406659
106Inflammatory bowel disease (IBD)_Homo sapiens_hsa053210.15536098
107Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.15173689
108Olfactory transduction_Homo sapiens_hsa047400.13550242
1092-Oxocarboxylic acid metabolism_Homo sapiens_hsa012100.13404088
110Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.13090174
111SNARE interactions in vesicular transport_Homo sapiens_hsa041300.12573939
112Sulfur metabolism_Homo sapiens_hsa009200.12313440
113Leishmaniasis_Homo sapiens_hsa051400.11418005
114Pathways in cancer_Homo sapiens_hsa052000.10901486
115Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004000.10697304
116Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.10407020
117Autoimmune thyroid disease_Homo sapiens_hsa053200.09904180
118Viral myocarditis_Homo sapiens_hsa054160.09829512
119Collecting duct acid secretion_Homo sapiens_hsa049660.08920197
120Fatty acid metabolism_Homo sapiens_hsa012120.08412278
121Wnt signaling pathway_Homo sapiens_hsa043100.07375294
122Nitrogen metabolism_Homo sapiens_hsa009100.02749954
123Arginine and proline metabolism_Homo sapiens_hsa003300.00768872
124Hedgehog signaling pathway_Homo sapiens_hsa04340-0.0578371

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