RPS4XP11

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1ribosomal small subunit assembly (GO:0000028)7.40934232
2chaperone-mediated protein transport (GO:0072321)7.07795004
3viral transcription (GO:0019083)6.87864030
4ribosomal small subunit biogenesis (GO:0042274)6.64793230
5translational termination (GO:0006415)6.57343858
6DNA deamination (GO:0045006)5.84000663
7translational elongation (GO:0006414)5.81146079
8SRP-dependent cotranslational protein targeting to membrane (GO:0006614)5.64517493
9cotranslational protein targeting to membrane (GO:0006613)5.54923218
10ATP synthesis coupled proton transport (GO:0015986)5.53429281
11energy coupled proton transport, down electrochemical gradient (GO:0015985)5.53429281
12protein targeting to ER (GO:0045047)5.51862905
13establishment of protein localization to endoplasmic reticulum (GO:0072599)5.26293687
14maturation of SSU-rRNA (GO:0030490)5.23875785
15protein localization to endoplasmic reticulum (GO:0070972)5.20379873
16viral life cycle (GO:0019058)4.99536438
17cellular protein complex disassembly (GO:0043624)4.98006739
18establishment of protein localization to mitochondrial membrane (GO:0090151)4.84126552
19mitochondrial ATP synthesis coupled proton transport (GO:0042776)4.75835389
20nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184)4.65550961
21ribosomal large subunit biogenesis (GO:0042273)4.41652779
22regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:00450914.34422083
23translational initiation (GO:0006413)4.32321915
24cytidine deamination (GO:0009972)4.30731305
25cytidine metabolic process (GO:0046087)4.30731305
26cytidine catabolic process (GO:0006216)4.30731305
27protein complex disassembly (GO:0043241)4.05186196
28translation (GO:0006412)3.90517730
29GTP biosynthetic process (GO:0006183)3.89093566
30protein neddylation (GO:0045116)3.83726599
31macromolecular complex disassembly (GO:0032984)3.78641281
32protein targeting to membrane (GO:0006612)3.74896325
33behavioral response to nicotine (GO:0035095)3.69569039
34mitochondrial electron transport, NADH to ubiquinone (GO:0006120)3.69405383
35neurofilament cytoskeleton organization (GO:0060052)3.63785184
36protein-cofactor linkage (GO:0018065)3.59614451
37pyrimidine ribonucleoside catabolic process (GO:0046133)3.58396959
38ribonucleoprotein complex biogenesis (GO:0022613)3.53346218
39respiratory electron transport chain (GO:0022904)3.48350365
40tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388)3.47060064
41RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394)3.47060064
42electron transport chain (GO:0022900)3.45597387
43nuclear-transcribed mRNA catabolic process (GO:0000956)3.42155748
44cellular component biogenesis (GO:0044085)3.41588933
45mitochondrial respiratory chain complex I biogenesis (GO:0097031)3.35374317
46mitochondrial respiratory chain complex I assembly (GO:0032981)3.35374317
47NADH dehydrogenase complex assembly (GO:0010257)3.35374317
48exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay 3.33948272
49nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291)3.31278872
50purine ribonucleoside triphosphate biosynthetic process (GO:0009206)3.31097360
51UTP biosynthetic process (GO:0006228)3.30916726
52UTP metabolic process (GO:0046051)3.27738564
53purine nucleoside triphosphate biosynthetic process (GO:0009145)3.27355452
54protein complex biogenesis (GO:0070271)3.25644445
55mRNA catabolic process (GO:0006402)3.20394499
56intracellular protein transmembrane import (GO:0044743)3.19662974
57negative regulation of T cell differentiation in thymus (GO:0033085)3.18921943
58ATP biosynthetic process (GO:0006754)3.12782768
59negative regulation of telomere maintenance (GO:0032205)3.10160472
60positive regulation of fatty acid transport (GO:2000193)3.00333446
61positive regulation of tyrosine phosphorylation of Stat5 protein (GO:0042523)2.99773855
62mitochondrial respiratory chain complex assembly (GO:0033108)2.91883413
63RNA catabolic process (GO:0006401)2.87749195
64positive regulation of defense response to virus by host (GO:0002230)2.83872492
65protein targeting to mitochondrion (GO:0006626)2.82792939
66rRNA processing (GO:0006364)2.82507908
67positive regulation of prostaglandin secretion (GO:0032308)2.82439395
68ribonucleoside triphosphate biosynthetic process (GO:0009201)2.81497174
69rRNA metabolic process (GO:0016072)2.81179615
70guanosine-containing compound biosynthetic process (GO:1901070)2.79683941
71rRNA catabolic process (GO:0016075)2.78492196
72positive regulation of T cell apoptotic process (GO:0070234)2.78408573
73positive regulation of icosanoid secretion (GO:0032305)2.76444657
74kynurenine metabolic process (GO:0070189)2.76234832
75regulation of tyrosine phosphorylation of Stat5 protein (GO:0042522)2.74884964
76ncRNA 3-end processing (GO:0043628)2.74723488
77protein polyglutamylation (GO:0018095)2.72958074
78pseudouridine synthesis (GO:0001522)2.70313469
79interferon-gamma production (GO:0032609)2.66657923
80hydrogen ion transmembrane transport (GO:1902600)2.66427234
81mast cell activation (GO:0045576)2.65474695
82mast cell activation involved in immune response (GO:0002279)2.64775716
83mast cell degranulation (GO:0043303)2.64775716
84glyoxylate metabolic process (GO:0046487)2.63290504
85pyrimidine nucleoside triphosphate metabolic process (GO:0009147)2.60762981
86establishment of protein localization to mitochondrion (GO:0072655)2.60418496
87water-soluble vitamin biosynthetic process (GO:0042364)2.59134963
88protein targeting (GO:0006605)2.55397589
89regulation of cilium movement (GO:0003352)2.55223891
90deoxyribonucleoside monophosphate metabolic process (GO:0009162)2.53396595
91establishment of protein localization to membrane (GO:0090150)2.52190519
92CTP biosynthetic process (GO:0006241)2.49723643
93CTP metabolic process (GO:0046036)2.49723643
94pyrimidine nucleoside triphosphate biosynthetic process (GO:0009148)2.47767413
95proton transport (GO:0015992)2.46423564
96cellular response to interleukin-15 (GO:0071350)2.46166578
97regulation of isotype switching to IgG isotypes (GO:0048302)2.45808413
98parturition (GO:0007567)2.44857553
99inner mitochondrial membrane organization (GO:0007007)2.44315843
100nucleoside triphosphate biosynthetic process (GO:0009142)2.43044494

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1GABP_17652178_ChIP-ChIP_JURKAT_Human3.94130095
2SOX9_22984422_ChIP-ChIP_TESTIS_Rat3.49712945
3ELF1_17652178_ChIP-ChIP_JURKAT_Human3.25312846
4KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human3.18983748
5HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human3.10171064
6VDR_22108803_ChIP-Seq_LS180_Human3.07444984
7EST1_17652178_ChIP-ChIP_JURKAT_Human3.03709681
8ETS1_20019798_ChIP-Seq_JURKAT_Human2.85862222
9RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse2.84114321
10TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat2.81553647
11JARID1A_20064375_ChIP-Seq_MESCs_Mouse2.73865493
12HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse2.61288363
13ZNF274_21170338_ChIP-Seq_K562_Hela2.43725692
14E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse2.30843182
15EZH2_22144423_ChIP-Seq_EOC_Human2.30067962
16VDR_23849224_ChIP-Seq_CD4+_Human2.22568227
17IRF1_19129219_ChIP-ChIP_H3396_Human2.16584028
18MYC_18555785_ChIP-Seq_MESCs_Mouse1.98547006
19FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse1.98101889
20MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.97267814
21FOXP3_21729870_ChIP-Seq_TREG_Human1.93517762
22CHD1_19587682_ChIP-ChIP_MESCs_Mouse1.88513995
23HCFC1_20581084_ChIP-Seq_MESCs_Mouse1.85933737
24IRF1_21803131_ChIP-Seq_MONOCYTES_Human1.76627714
25BMI1_23680149_ChIP-Seq_NPCS_Mouse1.74716253
26MYC_18940864_ChIP-ChIP_HL60_Human1.73582340
27BP1_19119308_ChIP-ChIP_Hs578T_Human1.64645753
28YY1_21170310_ChIP-Seq_MESCs_Mouse1.63870347
29ELK1_19687146_ChIP-ChIP_HELA_Human1.63393252
30NOTCH1_21737748_ChIP-Seq_TLL_Human1.59436758
31IGF1R_20145208_ChIP-Seq_DFB_Human1.57049725
32SRF_21415370_ChIP-Seq_HL-1_Mouse1.56842344
33TP53_22573176_ChIP-Seq_HFKS_Human1.56371306
34IRF8_22096565_ChIP-ChIP_GC-B_Human1.49401878
35TTF2_22483619_ChIP-Seq_HELA_Human1.48293519
36EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human1.43252193
37NANOG_20526341_ChIP-Seq_ESCs_Human1.43179171
38ELK1_22589737_ChIP-Seq_MCF10A_Human1.42208119
39LYL1_20887958_ChIP-Seq_HPC-7_Mouse1.41662737
40STAT6_20620947_ChIP-Seq_CD4_POS_T_Human1.41516082
41TAF2_19829295_ChIP-Seq_ESCs_Human1.36598607
42RBPJ_21746931_ChIP-Seq_IB4-LCL_Human1.34540453
43XRN2_22483619_ChIP-Seq_HELA_Human1.31363603
44MYC_18358816_ChIP-ChIP_MESCs_Mouse1.30290215
45NCOR_22424771_ChIP-Seq_293T_Human1.30176317
46AUTS2_25519132_ChIP-Seq_293T-REX_Human1.29868763
47CEBPA_26348894_ChIP-Seq_LIVER_Mouse1.25283964
48NOTCH1_17114293_ChIP-ChIP_T-ALL_Human1.24999561
49EBNA1_20929547_Chip-Seq_RAJI-cells_Human1.24317945
50ERA_21632823_ChIP-Seq_H3396_Human1.24246405
51EBNA2_21746931_ChIP-Seq_IB4-LCL_Human1.23101502
52CREB1_15753290_ChIP-ChIP_HEK293T_Human1.22754318
53CHD7_19251738_ChIP-ChIP_MESCs_Mouse1.20574318
54CEBPB_24764292_ChIP-Seq_MC3T3_Mouse1.15340552
55AR_20517297_ChIP-Seq_VCAP_Human1.12072329
56MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human1.10874202
57NR4A2_19515692_ChIP-ChIP_MN9D_Mouse1.10595687
58FOXA1_25329375_ChIP-Seq_VCAP_Human1.10157122
59FOXA1_27270436_Chip-Seq_PROSTATE_Human1.10157122
60ETV2_25802403_ChIP-Seq_MESCs_Mouse1.10093689
61FLI1_20887958_ChIP-Seq_HPC-7_Mouse1.09836026
62FUS_26573619_Chip-Seq_HEK293_Human1.09820129
63POU5F1_18358816_ChIP-ChIP_MESCs_Mouse1.08100927
64GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse1.07818303
65YY1_22570637_ChIP-Seq_MALME-3M_Human1.04546296
66FOXH1_21741376_ChIP-Seq_ESCs_Human1.04329519
67GATA3_21878914_ChIP-Seq_MCF-7_Human1.03701376
68GATA6_21074721_ChIP-Seq_CACO-2_Mouse1.03135766
69GABP_19822575_ChIP-Seq_HepG2_Human1.02705878
70MYC_19079543_ChIP-ChIP_MESCs_Mouse1.01453314
71EZH2_27294783_Chip-Seq_ESCs_Mouse1.00924609
72CTCF_20526341_ChIP-Seq_ESCs_Human1.00811417
73JARID2_20064375_ChIP-Seq_MESCs_Mouse1.00562551
74CTBP1_25329375_ChIP-Seq_LNCAP_Human0.99690861
75PDX1_19855005_ChIP-ChIP_MIN6_Mouse0.99429842
76MYC_19829295_ChIP-Seq_ESCs_Human0.99306702
77PBX1_22567123_ChIP-ChIP_OVCAR3_Human0.98864441
78CEBPB_23403033_ChIP-Seq_LIVER_Mouse0.97987906
79P53_21459846_ChIP-Seq_SAOS-2_Human0.97879270
80CIITA_25753668_ChIP-Seq_RAJI_Human0.97305763
81GATA6_21074721_ChIP-Seq_CACO-2_Human0.96608421
82BCL6_27268052_Chip-Seq_Bcells_Human0.95558842
83E2F1_20622854_ChIP-Seq_HELA_Human0.95409261
84GATA3_26560356_Chip-Seq_TH2_Human0.95359679
85POU5F1_16153702_ChIP-ChIP_HESCs_Human0.95318816
86CBX2_27304074_Chip-Seq_ESCs_Mouse0.94524776
87FOXH1_21741376_ChIP-Seq_EPCs_Human0.93643905
88TAL1_20887958_ChIP-Seq_HPC-7_Mouse0.93581154
89EED_16625203_ChIP-ChIP_MESCs_Mouse0.93478077
90EWS_26573619_Chip-Seq_HEK293_Human0.92876187
91SA1_27219007_Chip-Seq_Bcells_Human0.91923277
92RBPJ_21746931_ChIP-Seq_IB4_Human0.89777148
93SRY_22984422_ChIP-ChIP_TESTIS_Rat0.89684683
94STAT4_19710469_ChIP-ChIP_TH1__Mouse0.89682443
95SIN3B_21632747_ChIP-Seq_MESCs_Mouse0.89198300
96BMI1_19503595_ChIP-Seq_MEFsC_Mouse0.87908108
97SUZ12_27294783_Chip-Seq_ESCs_Mouse0.87028354
98DCP1A_22483619_ChIP-Seq_HELA_Human0.86918197
99RNF2_27304074_Chip-Seq_NSC_Mouse0.86699330
100HOXB7_26014856_ChIP-Seq_BT474_Human0.86049654

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0009379_abnormal_foot_pigmentation4.55640609
2MP0005671_abnormal_response_to3.47838051
3MP0006292_abnormal_olfactory_placode3.25537575
4MP0002163_abnormal_gland_morphology2.68014025
5MP0002638_abnormal_pupillary_reflex2.46981264
6MP0004885_abnormal_endolymph2.32534263
7MP0002876_abnormal_thyroid_physiology2.30679343
8MP0008995_early_reproductive_senescence2.25277480
9MP0003646_muscle_fatigue2.20496880
10MP0005646_abnormal_pituitary_gland1.94797921
11MP0004145_abnormal_muscle_electrophysio1.92054020
12MP0002653_abnormal_ependyma_morphology1.91653797
13MP0006072_abnormal_retinal_apoptosis1.89373579
14MP0009333_abnormal_splenocyte_physiolog1.84299837
15MP0002160_abnormal_reproductive_system1.84200027
16MP0008875_abnormal_xenobiotic_pharmacok1.79462600
17MP0002102_abnormal_ear_morphology1.79225421
18MP0002837_dystrophic_cardiac_calcinosis1.79150525
19MP0005377_hearing/vestibular/ear_phenot1.77908698
20MP0003878_abnormal_ear_physiology1.77908698
21MP0001835_abnormal_antigen_presentation1.73578193
22MP0005084_abnormal_gallbladder_morpholo1.72915563
23MP0004142_abnormal_muscle_tone1.71212932
24MP0005389_reproductive_system_phenotype1.69014057
25MP0008872_abnormal_physiological_respon1.65517404
26MP0001986_abnormal_taste_sensitivity1.58747529
27MP0004147_increased_porphyrin_level1.58137105
28MP0002138_abnormal_hepatobiliary_system1.57331036
29MP0005551_abnormal_eye_electrophysiolog1.52281959
30MP0003011_delayed_dark_adaptation1.50236856
31MP0005379_endocrine/exocrine_gland_phen1.48980090
32MP0003763_abnormal_thymus_physiology1.47006911
33MP0002234_abnormal_pharynx_morphology1.43699411
34MP0005645_abnormal_hypothalamus_physiol1.42806272
35MP0009785_altered_susceptibility_to1.39999642
36MP0001188_hyperpigmentation1.39982325
37MP0003786_premature_aging1.39033420
38MP0001873_stomach_inflammation1.38418471
39MP0001905_abnormal_dopamine_level1.37512926
40MP0008877_abnormal_DNA_methylation1.36323123
41MP0001919_abnormal_reproductive_system1.34551254
42MP0002736_abnormal_nociception_after1.29615207
43MP0002148_abnormal_hypersensitivity_rea1.29332182
44MP0003787_abnormal_imprinting1.29275087
45MP0004742_abnormal_vestibular_system1.28817566
46MP0001348_abnormal_lacrimal_gland1.27116868
47MP0005000_abnormal_immune_tolerance1.25991230
48MP0001968_abnormal_touch/_nociception1.25018850
49MP0001800_abnormal_humoral_immune1.24538227
50MP0001485_abnormal_pinna_reflex1.19901273
51MP0006276_abnormal_autonomic_nervous1.16541186
52MP0008789_abnormal_olfactory_epithelium1.16512410
53MP0005253_abnormal_eye_physiology1.15424150
54MP0000372_irregular_coat_pigmentation1.14809786
55MP0000049_abnormal_middle_ear1.10109393
56MP0002723_abnormal_immune_serum1.09273624
57MP0003186_abnormal_redox_activity1.08564991
58MP0004043_abnormal_pH_regulation1.03504416
59MP0009764_decreased_sensitivity_to1.03346132
60MP0009745_abnormal_behavioral_response1.02671077
61MP0005410_abnormal_fertilization1.02122428
62MP0005387_immune_system_phenotype1.01674101
63MP0001790_abnormal_immune_system1.01674101
64MP0002272_abnormal_nervous_system1.01163901
65MP0001293_anophthalmia1.00847545
66MP0003195_calcinosis1.00124178
67MP0003866_abnormal_defecation0.98396613
68MP0001501_abnormal_sleep_pattern0.97572507
69MP0002420_abnormal_adaptive_immunity0.97496568
70MP0006036_abnormal_mitochondrial_physio0.96639556
71MP0001819_abnormal_immune_cell0.94784967
72MP0005025_abnormal_response_to0.92378884
73MP0000685_abnormal_immune_system0.90769163
74MP0000631_abnormal_neuroendocrine_gland0.89345775
75MP0005174_abnormal_tail_pigmentation0.84319464
76MP0002928_abnormal_bile_duct0.83667889
77MP0005195_abnormal_posterior_eye0.83487411
78MP0002398_abnormal_bone_marrow0.82722328
79MP0001970_abnormal_pain_threshold0.82489767
80MP0008775_abnormal_heart_ventricle0.82153671
81MP0002210_abnormal_sex_determination0.82072287
82MP0003436_decreased_susceptibility_to0.81609156
83MP0002277_abnormal_respiratory_mucosa0.81587226
84MP0000678_abnormal_parathyroid_gland0.81453745
85MP0001119_abnormal_female_reproductive0.81421574
86MP0002938_white_spotting0.80869555
87MP0001881_abnormal_mammary_gland0.79162105
88MP0002452_abnormal_antigen_presenting0.79066310
89MP0001984_abnormal_olfaction0.78950120
90MP0002822_catalepsy0.78607804
91MP0003123_paternal_imprinting0.78232345
92MP0005499_abnormal_olfactory_system0.77050554
93MP0005394_taste/olfaction_phenotype0.77050554
94MP0000716_abnormal_immune_system0.76811972
95MP0002733_abnormal_thermal_nociception0.75845211
96MP0001440_abnormal_grooming_behavior0.73979212
97MP0002405_respiratory_system_inflammati0.73230984
98MP0003880_abnormal_central_pattern0.72919560
99MP0001845_abnormal_inflammatory_respons0.72361707
100MP0002095_abnormal_skin_pigmentation0.71620374

Predicted human phenotypes

RankGene SetZ-score
1Reticulocytopenia (HP:0001896)5.65053312
23-Methylglutaconic aciduria (HP:0003535)3.89536502
3Absent rod-and cone-mediated responses on ERG (HP:0007688)3.74123509
4Aplastic anemia (HP:0001915)3.70864757
5Acute necrotizing encephalopathy (HP:0006965)3.66005198
6Congenital stationary night blindness (HP:0007642)3.52533668
7Abnormality of cells of the erythroid lineage (HP:0012130)3.49916371
8Mitochondrial inheritance (HP:0001427)3.39092500
9Molar tooth sign on MRI (HP:0002419)3.22310806
10Abnormality of midbrain morphology (HP:0002418)3.22310806
11Abnormal mitochondria in muscle tissue (HP:0008316)3.17791305
12Increased CSF lactate (HP:0002490)3.12885066
13Acute encephalopathy (HP:0006846)3.10579951
14Absent thumb (HP:0009777)3.07026877
15Macrocytic anemia (HP:0001972)3.04377919
16Progressive macrocephaly (HP:0004481)3.03358480
17Abnormality of the renal collecting system (HP:0004742)2.99673746
18Pancreatic fibrosis (HP:0100732)2.88932815
19Abnormal rod and cone electroretinograms (HP:0008323)2.87999161
20Increased hepatocellular lipid droplets (HP:0006565)2.85008174
21Chromosomal breakage induced by crosslinking agents (HP:0003221)2.82429464
22Oral leukoplakia (HP:0002745)2.80035745
23Pallor (HP:0000980)2.76974568
24Absent/shortened dynein arms (HP:0200106)2.74902114
25Dynein arm defect of respiratory motile cilia (HP:0012255)2.74902114
26Pancreatic cysts (HP:0001737)2.71555664
27Abnormal number of erythroid precursors (HP:0012131)2.66726522
28Duplicated collecting system (HP:0000081)2.65986935
29Renal cortical cysts (HP:0000803)2.64439670
30Cerebral edema (HP:0002181)2.63623005
31Abnormality of B cell number (HP:0010975)2.63459102
32Renal Fanconi syndrome (HP:0001994)2.60931716
33Abnormality of the phalanges of the 2nd finger (HP:0009541)2.60410268
34Hepatocellular necrosis (HP:0001404)2.59374110
35Chromsome breakage (HP:0040012)2.56742391
36Abnormality of the renal cortex (HP:0011035)2.56527479
37Elevated erythrocyte sedimentation rate (HP:0003565)2.55780002
38Increased IgM level (HP:0003496)2.52348384
39Lipid accumulation in hepatocytes (HP:0006561)2.50492855
40Hyperglycinemia (HP:0002154)2.48373343
41IgG deficiency (HP:0004315)2.48113423
42Stomatitis (HP:0010280)2.47285171
43Pancytopenia (HP:0001876)2.47248358
44Hepatic necrosis (HP:0002605)2.44605391
45True hermaphroditism (HP:0010459)2.38482564
46Pendular nystagmus (HP:0012043)2.38436420
47Decreased electroretinogram (ERG) amplitude (HP:0000654)2.38023628
48Optic disc pallor (HP:0000543)2.36257132
49Abnormality of DNA repair (HP:0003254)2.34914435
50Increased serum lactate (HP:0002151)2.33319991
51Abnormality of eosinophils (HP:0001879)2.29000667
52Increased intramyocellular lipid droplets (HP:0012240)2.28462624
53Aplasia/Hypoplasia of the uvula (HP:0010293)2.27657986
54Abolished electroretinogram (ERG) (HP:0000550)2.26495114
55Abnormality of alanine metabolism (HP:0010916)2.26457167
56Hyperalaninemia (HP:0003348)2.26457167
57Abnormality of pyruvate family amino acid metabolism (HP:0010915)2.26457167
58Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688)2.25204514
59Stomach cancer (HP:0012126)2.24341991
60Nephronophthisis (HP:0000090)2.18075439
61Lactic acidosis (HP:0003128)2.15990527
62Abnormal respiratory motile cilium morphology (HP:0005938)2.15577847
63Abnormal respiratory epithelium morphology (HP:0012253)2.15577847
64Decreased central vision (HP:0007663)2.15270682
65Abnormality of T cell number (HP:0011839)2.11752182
66Medial flaring of the eyebrow (HP:0010747)2.10402425
67Abnormal activity of mitochondrial respiratory chain (HP:0011922)2.06537288
68Decreased activity of mitochondrial respiratory chain (HP:0008972)2.06537288
69Colon cancer (HP:0003003)2.06478173
70Stenosis of the external auditory canal (HP:0000402)2.05768663
71Microretrognathia (HP:0000308)2.05355402
72Congenital, generalized hypertrichosis (HP:0004540)2.03704399
73Abnormal ciliary motility (HP:0012262)2.03170215
74Meckel diverticulum (HP:0002245)2.03024843
75Abnormal delayed hypersensitivity skin test (HP:0002963)2.01696747
76Attenuation of retinal blood vessels (HP:0007843)1.99898985
77Muscle abnormality related to mitochondrial dysfunction (HP:0003800)1.98836573
78Abnormality of T cells (HP:0002843)1.98767871
79Aplasia/Hypoplasia of the spleen (HP:0010451)1.97816792
80Lethargy (HP:0001254)1.97413774
81Abnormality of the ileum (HP:0001549)1.96932395
82Eosinophilia (HP:0001880)1.95393262
83Autoimmune hemolytic anemia (HP:0001890)1.94571257
84Abnormality of the renal medulla (HP:0100957)1.94491984
85Asplenia (HP:0001746)1.93672543
86Type II lissencephaly (HP:0007260)1.93452768
87Hypoproteinemia (HP:0003075)1.93262591
88Constricted visual fields (HP:0001133)1.92672045
89Methylmalonic acidemia (HP:0002912)1.88683665
90Horseshoe kidney (HP:0000085)1.87583083
91Partial duplication of the phalanx of hand (HP:0009999)1.85006026
92Severe combined immunodeficiency (HP:0004430)1.84293646
93Increased muscle lipid content (HP:0009058)1.83588492
94Autoimmune thrombocytopenia (HP:0001973)1.82369415
95Abnormality of the phalanges of the 5th finger (HP:0004213)1.82193159
96Abnormality of the middle phalanx of the 5th finger (HP:0004219)1.82087430
97Abnormality of pyrimidine metabolism (HP:0004353)1.81416521
98Abnormality of the preputium (HP:0100587)1.81158354
99Exertional dyspnea (HP:0002875)1.80816896
100Abnormal respiratory motile cilium physiology (HP:0012261)1.79893435

Predicted kinase interactions (KEA)

RankGene SetZ-score
1TAOK36.13642380
2TXK5.24896707
3BCKDK3.29268309
4CDK192.91024137
5MAP4K12.90347280
6ZAK2.88935916
7ADRBK22.27671780
8NUAK12.09221297
9TLK12.03283337
10NME21.86483256
11PINK11.80957573
12GRK11.78952669
13CAMKK21.77364895
14WNK41.71637156
15KIT1.70394162
16FRK1.61311282
17ITK1.57489562
18PIK3CA1.47909893
19TESK21.41905487
20PDK21.34183317
21PASK1.32887236
22VRK21.27092246
23DYRK21.26676519
24TEC1.26143150
25TIE11.24157157
26FES1.19057994
27STK161.18425034
28IKBKB1.15343034
29PRKCQ1.12700621
30KDR1.08619490
31CAMK11.02451643
32MAP2K71.01640375
33OXSR10.99546503
34CAMKK10.96137275
35VRK10.95831393
36IKBKE0.94208024
37LCK0.93368079
38BTK0.92025083
39GRK60.89987158
40BMPR1B0.87299896
41SYK0.87096896
42INSRR0.85433154
43RPS6KA50.83200226
44JAK30.79879655
45CSNK1G10.74325513
46MATK0.68823268
47STK390.68804729
48MST40.68068196
49MAP4K20.67446799
50WNK30.67350506
51MAP2K20.64735570
52OBSCN0.62365040
53NEK10.60849476
54PHKG10.57406390
55PHKG20.57406390
56GRK70.56976599
57TRPM70.56599473
58PIM20.55458200
59AURKA0.54086751
60MAPK130.54021398
61NLK0.53693616
62BUB10.53576813
63PRKCG0.53483015
64PIM10.53462404
65LYN0.53091946
66TBK10.51699681
67ADRBK10.51161656
68ATR0.50507815
69PRKCD0.49659922
70MAP3K140.48421999
71NME10.48234116
72IGF1R0.46955655
73PRKCA0.46888035
74GRK50.46815372
75MAP2K60.46788027
76MAP3K110.46153969
77TNK20.45718270
78LIMK10.45289550
79CSNK2A10.43793839
80PRKACA0.43727802
81CSNK2A20.42050606
82PKN10.39990053
83RPS6KA60.39462271
84ABL20.37913705
85DAPK30.37906841
86FLT30.37899583
87PIK3CG0.37762284
88CDK30.37004503
89MUSK0.36179549
90CSNK1G30.35313649
91RPS6KA40.35296221
92ILK0.33712806
93DAPK20.31519443
94ZAP700.30588725
95MAPKAPK50.30488721
96CSNK1G20.30330771
97CSNK1A10.29358368
98EPHA40.29265751
99AKT20.29156882
100BRSK20.28328156

Predicted pathways (KEGG)

RankGene SetZ-score
1Ribosome_Homo sapiens_hsa030105.87878884
2Oxidative phosphorylation_Homo sapiens_hsa001903.67168246
3Parkinsons disease_Homo sapiens_hsa050123.01181799
4Allograft rejection_Homo sapiens_hsa053302.77691580
5Proteasome_Homo sapiens_hsa030502.69866479
6Autoimmune thyroid disease_Homo sapiens_hsa053202.59423743
7Asthma_Homo sapiens_hsa053102.59056405
8Graft-versus-host disease_Homo sapiens_hsa053322.39211592
9Primary immunodeficiency_Homo sapiens_hsa053402.25107701
10Linoleic acid metabolism_Homo sapiens_hsa005912.17357281
11Type I diabetes mellitus_Homo sapiens_hsa049402.10810447
12Alzheimers disease_Homo sapiens_hsa050102.05328739
13Intestinal immune network for IgA production_Homo sapiens_hsa046721.94305991
14alpha-Linolenic acid metabolism_Homo sapiens_hsa005921.91530383
15RNA polymerase_Homo sapiens_hsa030201.89663807
16Huntingtons disease_Homo sapiens_hsa050161.88853025
17Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049321.84503439
18Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005631.73398762
19Cardiac muscle contraction_Homo sapiens_hsa042601.64265797
20Cytosolic DNA-sensing pathway_Homo sapiens_hsa046231.61561349
21RNA degradation_Homo sapiens_hsa030181.52611635
22Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006301.52348496
23Protein export_Homo sapiens_hsa030601.49727129
24Phototransduction_Homo sapiens_hsa047441.44229970
25Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030081.31765439
26Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001301.29244215
27Ether lipid metabolism_Homo sapiens_hsa005651.28599456
28Nitrogen metabolism_Homo sapiens_hsa009101.26472001
29Antigen processing and presentation_Homo sapiens_hsa046121.26155527
30Fanconi anemia pathway_Homo sapiens_hsa034601.25155345
31One carbon pool by folate_Homo sapiens_hsa006701.22838499
32Arachidonic acid metabolism_Homo sapiens_hsa005901.20247403
33Homologous recombination_Homo sapiens_hsa034401.14150517
34Synthesis and degradation of ketone bodies_Homo sapiens_hsa000721.12624298
35Inflammatory bowel disease (IBD)_Homo sapiens_hsa053211.11611144
36Rheumatoid arthritis_Homo sapiens_hsa053231.10261234
37Pyrimidine metabolism_Homo sapiens_hsa002401.06729131
38Hematopoietic cell lineage_Homo sapiens_hsa046401.04394859
39Sulfur metabolism_Homo sapiens_hsa009201.04151369
40Tryptophan metabolism_Homo sapiens_hsa003801.03322980
41Caffeine metabolism_Homo sapiens_hsa002321.02301216
42Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.97274828
43Peroxisome_Homo sapiens_hsa041460.94010967
44Cytokine-cytokine receptor interaction_Homo sapiens_hsa040600.92401055
45Basal transcription factors_Homo sapiens_hsa030220.91208159
46Mismatch repair_Homo sapiens_hsa034300.87011702
47Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046500.86698955
48Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.84989616
49Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.83997539
50Purine metabolism_Homo sapiens_hsa002300.83156126
51T cell receptor signaling pathway_Homo sapiens_hsa046600.82333389
52Olfactory transduction_Homo sapiens_hsa047400.78194670
53Fat digestion and absorption_Homo sapiens_hsa049750.71587585
54Propanoate metabolism_Homo sapiens_hsa006400.69981150
55Maturity onset diabetes of the young_Homo sapiens_hsa049500.68121321
56Steroid hormone biosynthesis_Homo sapiens_hsa001400.66859393
57Retinol metabolism_Homo sapiens_hsa008300.66836020
58DNA replication_Homo sapiens_hsa030300.64363858
59Cysteine and methionine metabolism_Homo sapiens_hsa002700.63928383
60Valine, leucine and isoleucine degradation_Homo sapiens_hsa002800.62038818
61Sulfur relay system_Homo sapiens_hsa041220.61989254
62Collecting duct acid secretion_Homo sapiens_hsa049660.61616597
63Systemic lupus erythematosus_Homo sapiens_hsa053220.61150495
64Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.59030234
65Regulation of autophagy_Homo sapiens_hsa041400.58029576
66Nucleotide excision repair_Homo sapiens_hsa034200.57854152
67Butanoate metabolism_Homo sapiens_hsa006500.57073162
68Metabolic pathways_Homo sapiens_hsa011000.56277912
69Chemical carcinogenesis_Homo sapiens_hsa052040.55248432
70Viral myocarditis_Homo sapiens_hsa054160.54296865
71Spliceosome_Homo sapiens_hsa030400.54142974
72Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.52367200
73NF-kappa B signaling pathway_Homo sapiens_hsa040640.51686130
74NOD-like receptor signaling pathway_Homo sapiens_hsa046210.50836709
75Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.50739290
76Morphine addiction_Homo sapiens_hsa050320.50616805
77Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.49313218
78Taurine and hypotaurine metabolism_Homo sapiens_hsa004300.48725163
79Nicotine addiction_Homo sapiens_hsa050330.48256388
80RNA transport_Homo sapiens_hsa030130.47547073
81Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.44868150
82Ovarian steroidogenesis_Homo sapiens_hsa049130.44718430
83RIG-I-like receptor signaling pathway_Homo sapiens_hsa046220.43973749
84Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.43507541
85Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.41237891
86SNARE interactions in vesicular transport_Homo sapiens_hsa041300.40577222
87Drug metabolism - cytochrome P450_Homo sapiens_hsa009820.39232088
88Pyruvate metabolism_Homo sapiens_hsa006200.39230075
89Base excision repair_Homo sapiens_hsa034100.37511159
90Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004000.37410077
91Taste transduction_Homo sapiens_hsa047420.35924326
92Drug metabolism - other enzymes_Homo sapiens_hsa009830.35490042
93Serotonergic synapse_Homo sapiens_hsa047260.33531278
94Ascorbate and aldarate metabolism_Homo sapiens_hsa000530.31355301
95Salivary secretion_Homo sapiens_hsa049700.29423747
96Staphylococcus aureus infection_Homo sapiens_hsa051500.29268485
97Vitamin digestion and absorption_Homo sapiens_hsa049770.28923661
98Malaria_Homo sapiens_hsa051440.27286651
99Fatty acid biosynthesis_Homo sapiens_hsa000610.23532209
100Measles_Homo sapiens_hsa051620.21183824

Most similar genes based on co-expression Upload to Enrichr

Tissue Expression Export image »

Cell Line Expression Export image »