RPS2P32

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1ribosomal small subunit assembly (GO:0000028)6.28229562
2maturation of SSU-rRNA (GO:0030490)6.15856670
3ribosomal small subunit biogenesis (GO:0042274)6.02242500
4chaperone-mediated protein transport (GO:0072321)5.67665370
5viral transcription (GO:0019083)5.46959381
6translational termination (GO:0006415)5.21688139
7base-excision repair, AP site formation (GO:0006285)4.93301052
8SRP-dependent cotranslational protein targeting to membrane (GO:0006614)4.65328773
9energy coupled proton transport, down electrochemical gradient (GO:0015985)4.60747353
10ATP synthesis coupled proton transport (GO:0015986)4.60747353
11translational elongation (GO:0006414)4.58998248
12proteasome assembly (GO:0043248)4.58845623
13cotranslational protein targeting to membrane (GO:0006613)4.55405224
14protein targeting to ER (GO:0045047)4.54598567
15mitochondrial ATP synthesis coupled proton transport (GO:0042776)4.53545969
16protein localization to endoplasmic reticulum (GO:0070972)4.31366974
17establishment of protein localization to endoplasmic reticulum (GO:0072599)4.27775053
18viral life cycle (GO:0019058)4.19947992
19mannosylation (GO:0097502)4.11264556
20DNA strand renaturation (GO:0000733)4.07683310
21pyrimidine deoxyribonucleotide catabolic process (GO:0009223)4.04137674
22RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394)4.02370455
23tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388)4.02370455
24mitochondrial respiratory chain complex I biogenesis (GO:0097031)3.97695259
25mitochondrial respiratory chain complex I assembly (GO:0032981)3.97695259
26NADH dehydrogenase complex assembly (GO:0010257)3.97695259
27male meiosis I (GO:0007141)3.97057186
28purine deoxyribonucleotide catabolic process (GO:0009155)3.92784857
29cellular protein complex disassembly (GO:0043624)3.92694264
30establishment of protein localization to mitochondrial membrane (GO:0090151)3.91537174
31translational initiation (GO:0006413)3.88644828
32ribonucleoprotein complex biogenesis (GO:0022613)3.88585708
33nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184)3.84234813
34protein complex biogenesis (GO:0070271)3.80518682
35piRNA metabolic process (GO:0034587)3.77982174
36synapsis (GO:0007129)3.75279613
37kinetochore assembly (GO:0051382)3.73325596
38ribosomal large subunit biogenesis (GO:0042273)3.69765872
39deoxyribonucleotide catabolic process (GO:0009264)3.65864701
40translation (GO:0006412)3.64541001
41cellular component biogenesis (GO:0044085)3.64199321
42respiratory electron transport chain (GO:0022904)3.62676992
43meiosis I (GO:0007127)3.60599566
44electron transport chain (GO:0022900)3.58153921
45mitochondrial electron transport, NADH to ubiquinone (GO:0006120)3.51215888
46mitochondrial respiratory chain complex assembly (GO:0033108)3.49059063
47iron-sulfur cluster assembly (GO:0016226)3.47140437
48metallo-sulfur cluster assembly (GO:0031163)3.47140437
49deoxyribose phosphate catabolic process (GO:0046386)3.43802667
50cell wall macromolecule catabolic process (GO:0016998)3.41178964
51regulation of mitochondrial translation (GO:0070129)3.37445839
52ubiquinone biosynthetic process (GO:0006744)3.33453103
53peptidyl-histidine modification (GO:0018202)3.32848020
54tRNA processing (GO:0008033)3.31778888
55protein complex disassembly (GO:0043241)3.30688044
56ribosome biogenesis (GO:0042254)3.28983935
57kinetochore organization (GO:0051383)3.27925462
58rRNA processing (GO:0006364)3.27519066
59deoxyribonucleoside triphosphate metabolic process (GO:0009200)3.27045158
60protein-cofactor linkage (GO:0018065)3.24701692
61purine deoxyribonucleotide metabolic process (GO:0009151)3.21166401
62rRNA metabolic process (GO:0016072)3.18891421
632-deoxyribonucleotide metabolic process (GO:0009394)3.16292288
64pyrimidine nucleotide catabolic process (GO:0006244)3.14220614
65pyrimidine deoxyribonucleotide metabolic process (GO:0009219)3.10293380
66nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291)3.08023762
67regulation of cilium movement (GO:0003352)3.06618141
68exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay 3.05952292
69macromolecular complex disassembly (GO:0032984)3.05194039
70nuclear-transcribed mRNA catabolic process (GO:0000956)3.00285830
71meiotic chromosome segregation (GO:0045132)2.98092930
72aerobic respiration (GO:0009060)2.97664318
73protein targeting to mitochondrion (GO:0006626)2.96948103
74protein targeting to membrane (GO:0006612)2.96452583
75resolution of meiotic recombination intermediates (GO:0000712)2.96261835
76respiratory chain complex IV assembly (GO:0008535)2.96084832
77RNA phosphodiester bond hydrolysis, endonucleolytic (GO:0090502)2.94912922
78establishment of protein localization to mitochondrion (GO:0072655)2.94138928
79cytochrome complex assembly (GO:0017004)2.92429163
80positive regulation of prostaglandin secretion (GO:0032308)2.92004295
81platelet dense granule organization (GO:0060155)2.89498285
82deoxyribose phosphate metabolic process (GO:0019692)2.88276191
83pseudouridine synthesis (GO:0001522)2.87688738
84ubiquinone metabolic process (GO:0006743)2.87122331
85GTP biosynthetic process (GO:0006183)2.86180028
86ncRNA processing (GO:0034470)2.86025994
87protein neddylation (GO:0045116)2.85392653
88mRNA catabolic process (GO:0006402)2.85382217
89chromatin remodeling at centromere (GO:0031055)2.83513956
90chromosome organization involved in meiosis (GO:0070192)2.82879109
91UV protection (GO:0009650)2.82336927
92negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436)2.79281499
93tRNA modification (GO:0006400)2.78170131
94tRNA metabolic process (GO:0006399)2.76676255
95rRNA modification (GO:0000154)2.74532592
96negative regulation of mast cell activation (GO:0033004)2.73320771
97positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051437)2.72574736
98preassembly of GPI anchor in ER membrane (GO:0016254)2.71628110
99DNA catabolic process, exonucleolytic (GO:0000738)2.70773142
100RNA catabolic process (GO:0006401)2.69920957

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human4.18084056
2GABP_17652178_ChIP-ChIP_JURKAT_Human4.02233118
3JARID1A_20064375_ChIP-Seq_MESCs_Mouse3.95743972
4SOX9_22984422_ChIP-ChIP_TESTIS_Rat3.74042438
5ETS1_20019798_ChIP-Seq_JURKAT_Human3.31675239
6NOTCH1_17114293_ChIP-ChIP_T-ALL_Human3.30098682
7MYC_18555785_ChIP-Seq_MESCs_Mouse3.20003016
8EST1_17652178_ChIP-ChIP_JURKAT_Human3.12364314
9HCFC1_20581084_ChIP-Seq_MESCs_Mouse2.89414141
10MYC_18358816_ChIP-ChIP_MESCs_Mouse2.80984389
11E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse2.77850329
12HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human2.77465455
13CREB1_15753290_ChIP-ChIP_HEK293T_Human2.65668928
14VDR_23849224_ChIP-Seq_CD4+_Human2.61105507
15XRN2_22483619_ChIP-Seq_HELA_Human2.58101393
16EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse2.55322907
17SRF_21415370_ChIP-Seq_HL-1_Mouse2.38656551
18THAP11_20581084_ChIP-Seq_MESCs_Mouse2.34732011
19FOXP3_21729870_ChIP-Seq_TREG_Human2.25627723
20GABP_19822575_ChIP-Seq_HepG2_Human2.22395142
21MYCN_21190229_ChIP-Seq_SHEP-21N_Human2.19832443
22CHD1_19587682_ChIP-ChIP_MESCs_Mouse2.12853970
23MYC_19079543_ChIP-ChIP_MESCs_Mouse2.11982655
24VDR_21846776_ChIP-Seq_THP-1_Human2.09642376
25CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human2.05554336
26CEBPB_24764292_ChIP-Seq_MC3T3_Mouse2.03510645
27MYC_19030024_ChIP-ChIP_MESCs_Mouse1.98192907
28PDX1_19855005_ChIP-ChIP_MIN6_Mouse1.96309590
29SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse1.93599695
30DCP1A_22483619_ChIP-Seq_HELA_Human1.90590569
31TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat1.87364814
32TTF2_22483619_ChIP-Seq_HELA_Human1.81044034
33CEBPB_23403033_ChIP-Seq_LIVER_Mouse1.78161820
34MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse1.76512367
35E2F4_17652178_ChIP-ChIP_JURKAT_Human1.74812371
36FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human1.74379421
37FLI1_20887958_ChIP-Seq_HPC-7_Mouse1.74253492
38TAL1_20887958_ChIP-Seq_HPC-7_Mouse1.72345640
39CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human1.72235403
40CIITA_25753668_ChIP-Seq_RAJI_Human1.65322539
41ELF1_17652178_ChIP-ChIP_JURKAT_Human1.64464483
42YY1_21170310_ChIP-Seq_MESCs_Mouse1.63837828
43DACH1_20351289_ChIP-Seq_MDA-MB-231_Human1.63357452
44BCL6_27268052_Chip-Seq_Bcells_Human1.59913825
45E2F1_18555785_ChIP-Seq_MESCs_Mouse1.59543747
46FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse1.56649475
47TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse1.55336634
48KDM5A_27292631_Chip-Seq_BREAST_Human1.48425356
49P68_20966046_ChIP-Seq_HELA_Human1.46146030
50SPI1_22096565_ChIP-ChIP_GC-B_Mouse1.46129543
51POU5F1_18555785_ChIP-Seq_MESCs_Mouse1.45711070
52EBNA2_21746931_ChIP-Seq_IB4-LCL_Human1.45528519
53CEBPA_23403033_ChIP-Seq_LIVER_Mouse1.45192790
54ELF1_20517297_ChIP-Seq_JURKAT_Human1.43813391
55TET1_21451524_ChIP-Seq_MESCs_Mouse1.42655217
56RBPJ_21746931_ChIP-Seq_IB4-LCL_Human1.41569082
57PPARG_19300518_ChIP-PET_3T3-L1_Mouse1.39033445
58* E2F1_20622854_ChIP-Seq_HELA_Human1.37594346
59HOXB4_20404135_ChIP-ChIP_EML_Mouse1.37017460
60MYBL2_22936984_ChIP-ChIP_MESCs_Mouse1.34900964
61BCL3_23251550_ChIP-Seq_MUSCLE_Mouse1.33908910
62ELK1_19687146_ChIP-ChIP_HELA_Human1.32640834
63ZFP42_18358816_ChIP-ChIP_MESCs_Mouse1.32372016
64FOXP1_21924763_ChIP-Seq_HESCs_Human1.30563976
65YY1_22570637_ChIP-Seq_MALME-3M_Human1.27378859
66* BCOR_27268052_Chip-Seq_Bcells_Human1.26862432
67ERG_20887958_ChIP-Seq_HPC-7_Mouse1.25377279
68MAF_26560356_Chip-Seq_TH2_Human1.25273571
69NELFA_20434984_ChIP-Seq_ESCs_Mouse1.22698451
70CTCF_20526341_ChIP-Seq_ESCs_Human1.21018746
71E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human1.19141551
72ERA_21632823_ChIP-Seq_H3396_Human1.17314274
73TP63_19390658_ChIP-ChIP_HaCaT_Human1.16728874
74CCND1_20090754_ChIP-ChIP_RETINA_Mouse1.15737658
75FLI1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human1.10535448
76UTX_26944678_Chip-Seq_JUKART_Human1.10441548
77NANOG_20526341_ChIP-Seq_ESCs_Human1.09779733
78* P300_27268052_Chip-Seq_Bcells_Human1.09401781
79MYC_18940864_ChIP-ChIP_HL60_Human1.07777676
80E2F7_22180533_ChIP-Seq_HELA_Human1.06620575
81PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse1.06354643
82* PHF8_20622854_ChIP-Seq_HELA_Human1.05123371
83SFPI1_20887958_ChIP-Seq_HPC-7_Mouse1.04679048
84GFI1B_20887958_ChIP-Seq_HPC-7_Mouse1.04573360
85SIN3A_21632747_ChIP-Seq_MESCs_Mouse1.02795337
86TP53_22573176_ChIP-Seq_HFKS_Human1.02079994
87* SMAD2/3_21741376_ChIP-Seq_ESCs_Human0.99419923
88CTCF_18555785_ChIP-Seq_MESCs_Mouse0.97509848
89RUNX1_20887958_ChIP-Seq_HPC-7_Mouse0.97487790
90SPI1_23547873_ChIP-Seq_NB4_Human0.97212316
91TAF2_19829295_ChIP-Seq_ESCs_Human0.94644923
92DMRT1_21621532_ChIP-ChIP_FETAL_Ovary0.94390190
93EGR1_23403033_ChIP-Seq_LIVER_Mouse0.93848261
94RXRA_24833708_ChIP-Seq_LIVER_Mouse0.93742960
95YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse0.92749893
96E2F1_21310950_ChIP-Seq_MCF-7_Human0.92347284
97ZNF274_21170338_ChIP-Seq_K562_Hela0.92280158
98RARA_24833708_ChIP-Seq_LIVER_Mouse0.90240433
99SIN3B_21632747_ChIP-Seq_MESCs_Mouse0.89299212
100ZFX_18555785_ChIP-Seq_MESCs_Mouse0.88549010

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0009379_abnormal_foot_pigmentation4.50687937
2MP0008058_abnormal_DNA_repair3.61590413
3MP0005174_abnormal_tail_pigmentation3.18738833
4MP0003186_abnormal_redox_activity2.81490066
5MP0008875_abnormal_xenobiotic_pharmacok2.61663840
6MP0006292_abnormal_olfactory_placode2.48986434
7MP0000372_irregular_coat_pigmentation2.40937213
8MP0005171_absent_coat_pigmentation2.26166904
9MP0002160_abnormal_reproductive_system2.21670527
10MP0001986_abnormal_taste_sensitivity2.19593998
11MP0003136_yellow_coat_color2.17520482
12MP0006036_abnormal_mitochondrial_physio2.13855010
13MP0001764_abnormal_homeostasis2.10948734
14MP0010094_abnormal_chromosome_stability2.08455719
15MP0002163_abnormal_gland_morphology2.05731480
16MP0003646_muscle_fatigue1.95946392
17MP0003123_paternal_imprinting1.94916176
18MP0001835_abnormal_antigen_presentation1.91199372
19MP0003718_maternal_effect1.85752596
20MP0001293_anophthalmia1.80463816
21MP0008007_abnormal_cellular_replicative1.77433508
22MP0002132_abnormal_respiratory_system1.74397064
23MP0003806_abnormal_nucleotide_metabolis1.73573929
24MP0001905_abnormal_dopamine_level1.68601947
25MP0005423_abnormal_somatic_nervous1.66878511
26MP0002095_abnormal_skin_pigmentation1.60207122
27MP0005410_abnormal_fertilization1.59761404
28MP0002736_abnormal_nociception_after1.56207531
29MP0000015_abnormal_ear_pigmentation1.54946553
30MP0005389_reproductive_system_phenotype1.52011972
31MP0003786_premature_aging1.48335016
32MP0003111_abnormal_nucleus_morphology1.47819412
33MP0001853_heart_inflammation1.45899634
34MP0002837_dystrophic_cardiac_calcinosis1.45441117
35MP0001968_abnormal_touch/_nociception1.44578135
36MP0002210_abnormal_sex_determination1.41269144
37MP0003077_abnormal_cell_cycle1.38682704
38MP0002254_reproductive_system_inflammat1.33029205
39MP0003011_delayed_dark_adaptation1.32987642
40MP0009764_decreased_sensitivity_to1.31809626
41MP0001929_abnormal_gametogenesis1.30132160
42MP0005551_abnormal_eye_electrophysiolog1.27413911
43MP0004142_abnormal_muscle_tone1.26919915
44MP0002876_abnormal_thyroid_physiology1.26414930
45MP0004147_increased_porphyrin_level1.26011969
46MP0000358_abnormal_cell_content/1.22628628
47MP0000750_abnormal_muscle_regeneration1.22097052
48MP0005332_abnormal_amino_acid1.21445633
49MP0009333_abnormal_splenocyte_physiolog1.20197007
50MP0005397_hematopoietic_system_phenotyp1.19530187
51MP0001545_abnormal_hematopoietic_system1.19530187
52MP0002148_abnormal_hypersensitivity_rea1.19460447
53MP0003693_abnormal_embryo_hatching1.18710779
54MP0001919_abnormal_reproductive_system1.11644075
55MP0001145_abnormal_male_reproductive1.10979156
56MP0003698_abnormal_male_reproductive1.03830042
57MP0001800_abnormal_humoral_immune1.03386290
58MP0005075_abnormal_melanosome_morpholog1.02702897
59MP0000653_abnormal_sex_gland1.01868217
60MP0002234_abnormal_pharynx_morphology1.00528113
61MP0008789_abnormal_olfactory_epithelium1.00151258
62MP0002723_abnormal_immune_serum0.98236414
63MP0008872_abnormal_physiological_respon0.97732145
64MP0006035_abnormal_mitochondrial_morpho0.97196931
65MP0005670_abnormal_white_adipose0.97183480
66MP0004957_abnormal_blastocyst_morpholog0.95969962
67MP0002735_abnormal_chemical_nociception0.95370497
68MP0003763_abnormal_thymus_physiology0.93690370
69MP0005000_abnormal_immune_tolerance0.92156790
70MP0005084_abnormal_gallbladder_morpholo0.91312977
71MP0002420_abnormal_adaptive_immunity0.90108732
72MP0000685_abnormal_immune_system0.90055083
73MP0001819_abnormal_immune_cell0.88872327
74MP0002452_abnormal_antigen_presenting0.86093562
75MP0008469_abnormal_protein_level0.86045927
76MP0002938_white_spotting0.84167607
77MP0005645_abnormal_hypothalamus_physiol0.83583661
78MP0001756_abnormal_urination0.83545085
79MP0001324_abnormal_eye_pigmentation0.83193439
80MP0001661_extended_life_span0.82040792
81MP0006082_CNS_inflammation0.81895399
82MP0004019_abnormal_vitamin_homeostasis0.80706484
83MP0002019_abnormal_tumor_incidence0.80650379
84MP0001119_abnormal_female_reproductive0.80344752
85MP0002429_abnormal_blood_cell0.78140482
86MP0003436_decreased_susceptibility_to0.78021738
87MP0002398_abnormal_bone_marrow0.77950281
88MP0001873_stomach_inflammation0.77602977
89MP0000689_abnormal_spleen_morphology0.76782143
90MP0002405_respiratory_system_inflammati0.76148522
91MP0005025_abnormal_response_to0.74125132
92MP0000716_abnormal_immune_system0.72119041
93MP0001790_abnormal_immune_system0.70938013
94MP0005387_immune_system_phenotype0.70938013
95MP0004742_abnormal_vestibular_system0.70192521
96MP0005671_abnormal_response_to0.69253819
97MP0009278_abnormal_bone_marrow0.69090039
98MP0009785_altered_susceptibility_to0.69003060
99MP0001485_abnormal_pinna_reflex0.68610816
100MP0009643_abnormal_urine_homeostasis0.68490577

Predicted human phenotypes

RankGene SetZ-score
1Acute necrotizing encephalopathy (HP:0006965)4.98568953
2Reticulocytopenia (HP:0001896)4.80874933
3Abnormal mitochondria in muscle tissue (HP:0008316)4.59522969
4Mitochondrial inheritance (HP:0001427)4.50588788
5Acute encephalopathy (HP:0006846)4.44484763
6Increased CSF lactate (HP:0002490)4.33858155
7Progressive macrocephaly (HP:0004481)4.23454413
8Hepatocellular necrosis (HP:0001404)4.11585033
9Abnormality of pyruvate family amino acid metabolism (HP:0010915)3.83632621
10Abnormality of alanine metabolism (HP:0010916)3.83632621
11Hyperalaninemia (HP:0003348)3.83632621
12Increased hepatocellular lipid droplets (HP:0006565)3.67368609
13Hepatic necrosis (HP:0002605)3.58387069
14Increased intramyocellular lipid droplets (HP:0012240)3.36572649
15Abnormality of cells of the erythroid lineage (HP:0012130)3.35291517
16Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688)3.35009592
17Cerebral edema (HP:0002181)3.34947380
18Decreased electroretinogram (ERG) amplitude (HP:0000654)3.33900977
19Lipid accumulation in hepatocytes (HP:0006561)3.32048172
20Rectovaginal fistula (HP:0000143)3.19823078
21Rectal fistula (HP:0100590)3.19823078
22Renal Fanconi syndrome (HP:0001994)3.17260881
23Absent thumb (HP:0009777)3.17253431
24Increased serum lactate (HP:0002151)3.09909714
25Abnormality of midbrain morphology (HP:0002418)3.07090993
26Molar tooth sign on MRI (HP:0002419)3.07090993
27Abnormal number of erythroid precursors (HP:0012131)3.01888592
28Lactic acidosis (HP:0003128)2.96006304
29Testicular atrophy (HP:0000029)2.95142932
30Macrocytic anemia (HP:0001972)2.91844637
31Increased muscle lipid content (HP:0009058)2.90381656
323-Methylglutaconic aciduria (HP:0003535)2.88322574
33Exertional dyspnea (HP:0002875)2.87900509
34Respiratory difficulties (HP:0002880)2.84500008
35Pallor (HP:0000980)2.80572841
36Rib fusion (HP:0000902)2.76550492
37Abnormal activity of mitochondrial respiratory chain (HP:0011922)2.75754344
38Decreased activity of mitochondrial respiratory chain (HP:0008972)2.75754344
39Optic disc pallor (HP:0000543)2.75668083
40Microretrognathia (HP:0000308)2.74357867
41Type I transferrin isoform profile (HP:0003642)2.68219517
42Abnormality of DNA repair (HP:0003254)2.67510076
43Muscle abnormality related to mitochondrial dysfunction (HP:0003800)2.65168161
44Poikiloderma (HP:0001029)2.63436360
45Vaginal fistula (HP:0004320)2.58922207
46Intestinal fistula (HP:0100819)2.49486653
47Congenital stationary night blindness (HP:0007642)2.48097267
48Chronic hepatic failure (HP:0100626)2.42865080
49Exercise intolerance (HP:0003546)2.37853267
50Microvesicular hepatic steatosis (HP:0001414)2.25661984
51Attenuation of retinal blood vessels (HP:0007843)2.25658989
52Lethargy (HP:0001254)2.23965827
53Cerebral hypomyelination (HP:0006808)2.19225793
54Abnormality of T cell physiology (HP:0011840)2.17950386
55Respiratory failure (HP:0002878)2.12242695
56Leukodystrophy (HP:0002415)2.09922585
57Cerebellar dysplasia (HP:0007033)2.09274356
58Abnormal isoelectric focusing of serum transferrin (HP:0003160)2.08234606
59Abnormal protein N-linked glycosylation (HP:0012347)2.08234606
60Abnormal protein glycosylation (HP:0012346)2.08234606
61Abnormal glycosylation (HP:0012345)2.08234606
62Agammaglobulinemia (HP:0004432)2.07368179
63Increased IgM level (HP:0003496)2.05762501
64CNS demyelination (HP:0007305)2.01579643
65Cutaneous melanoma (HP:0012056)1.99988098
66Squamous cell carcinoma (HP:0002860)1.97414972
67Bile duct proliferation (HP:0001408)1.96554750
68Abnormal biliary tract physiology (HP:0012439)1.96554750
69Tachypnea (HP:0002789)1.96137455
70Emotional lability (HP:0000712)1.95981654
71Cleft eyelid (HP:0000625)1.94016847
72Thrombocytosis (HP:0001894)1.93543699
73Hypertensive crisis (HP:0100735)1.91964980
74Optic nerve coloboma (HP:0000588)1.91167251
75Pancreatic cysts (HP:0001737)1.89794423
76True hermaphroditism (HP:0010459)1.88994411
77Hyperglycinemia (HP:0002154)1.86524841
78Bony spicule pigmentary retinopathy (HP:0007737)1.85297351
79Abnormality of serum amino acid levels (HP:0003112)1.85000823
80Aplasia/Hypoplasia of the sacrum (HP:0008517)1.84685547
81Neutropenia (HP:0001875)1.83211099
82Nausea (HP:0002018)1.80964821
83Pancreatic fibrosis (HP:0100732)1.80286516
84Stomatitis (HP:0010280)1.80245158
85Progressive microcephaly (HP:0000253)1.79969579
86Muscle fiber atrophy (HP:0100295)1.79843541
87Aplastic anemia (HP:0001915)1.78397195
88Abnormality of renal resorption (HP:0011038)1.77867782
89Increased serum pyruvate (HP:0003542)1.76211184
90Nephronophthisis (HP:0000090)1.75982196
91Recurrent cutaneous fungal infections (HP:0011370)1.75682347
92Chronic mucocutaneous candidiasis (HP:0002728)1.75682347
93Methylmalonic aciduria (HP:0012120)1.74812246
94IgG deficiency (HP:0004315)1.74524446
95Hypoplasia of the radius (HP:0002984)1.74224483
96Type 2 muscle fiber atrophy (HP:0003554)1.71981035
97Aplasia/Hypoplasia of the uvula (HP:0010293)1.71408245
98Glycosuria (HP:0003076)1.68551163
99Abnormality of urine glucose concentration (HP:0011016)1.68551163
100Pancytopenia (HP:0001876)1.68513002

Predicted kinase interactions (KEA)

RankGene SetZ-score
1PDK25.03454041
2VRK24.78060174
3NEK13.54175431
4CDK193.21591882
5STK162.80774461
6NUAK12.60566547
7KDR2.51438336
8NME22.47891293
9BUB12.27316449
10NEK22.19147588
11BCKDK2.18705118
12TESK22.15877901
13SCYL22.13380774
14ZAK2.09135179
15TLK11.85183702
16CCNB11.81916661
17PLK41.72590265
18VRK11.67106594
19MAPKAPK51.66708963
20WNK41.66432246
21TAOK31.60997589
22MAPK151.57579147
23MAPKAPK31.56951781
24PNCK1.49923815
25ABL21.47383093
26MAP4K21.34320158
27NME11.34119275
28BRSK21.28351974
29PBK1.23284637
30ADRBK21.21276228
31OXSR11.20936322
32DYRK21.16291127
33CSF1R1.14488096
34TXK1.13699083
35IKBKB1.12099532
36MUSK1.06560543
37PIM20.96756043
38MAPK130.94939089
39TYK20.93393502
40TRPM70.86203571
41EEF2K0.85150499
42CDK40.83562490
43RPS6KB20.81456609
44PLK10.78783634
45AURKA0.77942779
46RPS6KA50.77280248
47CDC70.73705755
48MAPK110.72020550
49ATR0.71724945
50CHEK20.69734590
51SIK20.68054249
52MAPK120.67988401
53PINK10.67147796
54MAP3K110.66551693
55EIF2AK10.63702949
56BLK0.62289941
57BMX0.62102422
58WNK30.61883771
59DAPK30.60741398
60CDK11A0.59230603
61MARK30.59196710
62GRK10.56847783
63AURKB0.56800098
64ILK0.53361325
65CAMKK20.53333169
66IKBKE0.53079673
67MAP4K10.52484655
68KIT0.52298500
69LYN0.52042848
70TEC0.49847299
71BRSK10.48274757
72CDK150.48125808
73TAOK20.45228177
74IRAK30.44724167
75CAMK10.42425108
76ADRBK10.41110339
77PDPK10.40750795
78CDK180.40102193
79TIE10.39052327
80PIM10.37704112
81CDK140.37333717
82PRKCQ0.36839429
83CSNK2A20.36728653
84MAP2K20.36230259
85PAK10.35695906
86RPS6KA60.34954330
87TBK10.34930269
88SRPK10.34717048
89CSNK2A10.34670332
90NEK60.34095722
91MST1R0.33818420
92RPS6KA10.33348665
93CHEK10.33125993
94SYK0.32733305
95STK40.30792999
96IRAK40.29646076
97ACVR1B0.29497912
98RPS6KC10.28851210
99RPS6KL10.28851210
100IRAK20.28598740

Predicted pathways (KEGG)

RankGene SetZ-score
1Ribosome_Homo sapiens_hsa030104.96676441
2Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001303.70084209
3Oxidative phosphorylation_Homo sapiens_hsa001903.36841486
4Parkinsons disease_Homo sapiens_hsa050122.95332819
5Proteasome_Homo sapiens_hsa030502.92643580
6Sulfur relay system_Homo sapiens_hsa041222.59664283
7Asthma_Homo sapiens_hsa053102.44900932
8Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030082.36935463
9Homologous recombination_Homo sapiens_hsa034402.36761465
10DNA replication_Homo sapiens_hsa030302.25728587
11Base excision repair_Homo sapiens_hsa034102.17637776
12RNA polymerase_Homo sapiens_hsa030202.15459815
13Fanconi anemia pathway_Homo sapiens_hsa034602.06377004
14One carbon pool by folate_Homo sapiens_hsa006702.05719093
15Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049322.01241081
16Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005631.96790799
17Huntingtons disease_Homo sapiens_hsa050161.94796054
18Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006301.92034397
19Mismatch repair_Homo sapiens_hsa034301.90252434
20Intestinal immune network for IgA production_Homo sapiens_hsa046721.81654894
21Nucleotide excision repair_Homo sapiens_hsa034201.74334493
22Primary immunodeficiency_Homo sapiens_hsa053401.73845760
23Alzheimers disease_Homo sapiens_hsa050101.70332013
24Pyrimidine metabolism_Homo sapiens_hsa002401.70094820
25Allograft rejection_Homo sapiens_hsa053301.64880142
26Glutathione metabolism_Homo sapiens_hsa004801.55309269
27Autoimmune thyroid disease_Homo sapiens_hsa053201.46889253
28Protein export_Homo sapiens_hsa030601.41251471
29RNA transport_Homo sapiens_hsa030131.33610285
30Cardiac muscle contraction_Homo sapiens_hsa042601.32268776
31Basal transcription factors_Homo sapiens_hsa030221.32220413
32Fatty acid elongation_Homo sapiens_hsa000621.27284779
33Spliceosome_Homo sapiens_hsa030401.25599586
34Cytosolic DNA-sensing pathway_Homo sapiens_hsa046231.25361723
35RNA degradation_Homo sapiens_hsa030181.20525408
36Graft-versus-host disease_Homo sapiens_hsa053321.15666997
37Terpenoid backbone biosynthesis_Homo sapiens_hsa009001.15532045
38Purine metabolism_Homo sapiens_hsa002301.11075823
39Sulfur metabolism_Homo sapiens_hsa009201.10317741
40Glycine, serine and threonine metabolism_Homo sapiens_hsa002601.08751486
41Cysteine and methionine metabolism_Homo sapiens_hsa002701.05925796
42Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005331.01139069
43Folate biosynthesis_Homo sapiens_hsa007900.96760375
44Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009700.95429648
45Pyruvate metabolism_Homo sapiens_hsa006200.94267152
46Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.90432685
47Peroxisome_Homo sapiens_hsa041460.90152060
48Propanoate metabolism_Homo sapiens_hsa006400.88215254
49Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010400.84797172
50Rheumatoid arthritis_Homo sapiens_hsa053230.80513255
51Inflammatory bowel disease (IBD)_Homo sapiens_hsa053210.80232899
52Systemic lupus erythematosus_Homo sapiens_hsa053220.77305562
53Type I diabetes mellitus_Homo sapiens_hsa049400.77040188
54Synthesis and degradation of ketone bodies_Homo sapiens_hsa000720.76736363
55Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.76371605
56Citrate cycle (TCA cycle)_Homo sapiens_hsa000200.76170133
57Valine, leucine and isoleucine degradation_Homo sapiens_hsa002800.75693657
58Metabolic pathways_Homo sapiens_hsa011000.73682746
59Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005320.70438916
60Antigen processing and presentation_Homo sapiens_hsa046120.67447907
61Tyrosine metabolism_Homo sapiens_hsa003500.61792128
62N-Glycan biosynthesis_Homo sapiens_hsa005100.61583302
63alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.60661466
64Fatty acid metabolism_Homo sapiens_hsa012120.56693243
65Hematopoietic cell lineage_Homo sapiens_hsa046400.55936303
66Primary bile acid biosynthesis_Homo sapiens_hsa001200.55129948
67Chemical carcinogenesis_Homo sapiens_hsa052040.50194254
68Butanoate metabolism_Homo sapiens_hsa006500.48486558
69Phenylalanine metabolism_Homo sapiens_hsa003600.48190048
70Leishmaniasis_Homo sapiens_hsa051400.44281508
71Cell cycle_Homo sapiens_hsa041100.43025492
72Staphylococcus aureus infection_Homo sapiens_hsa051500.42826925
73Non-homologous end-joining_Homo sapiens_hsa034500.42353563
74Drug metabolism - cytochrome P450_Homo sapiens_hsa009820.40653309
75Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.38446438
76Carbon metabolism_Homo sapiens_hsa012000.37680186
77p53 signaling pathway_Homo sapiens_hsa041150.36757859
78Drug metabolism - other enzymes_Homo sapiens_hsa009830.35558911
79Epstein-Barr virus infection_Homo sapiens_hsa051690.35332702
80Phototransduction_Homo sapiens_hsa047440.34572442
81Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.33475055
82Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.33159316
83Fatty acid degradation_Homo sapiens_hsa000710.31988206
84NF-kappa B signaling pathway_Homo sapiens_hsa040640.29496033
85Linoleic acid metabolism_Homo sapiens_hsa005910.29061935
86Steroid hormone biosynthesis_Homo sapiens_hsa001400.27741768
87Viral myocarditis_Homo sapiens_hsa054160.27054246
88Arachidonic acid metabolism_Homo sapiens_hsa005900.26546299
89Cyanoamino acid metabolism_Homo sapiens_hsa004600.26283099
90Tryptophan metabolism_Homo sapiens_hsa003800.25831461
91Cytokine-cytokine receptor interaction_Homo sapiens_hsa040600.25751023
92Vitamin digestion and absorption_Homo sapiens_hsa049770.25732313
93Herpes simplex infection_Homo sapiens_hsa051680.25426337
94Collecting duct acid secretion_Homo sapiens_hsa049660.24396435
95Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.24081574
96Nitrogen metabolism_Homo sapiens_hsa009100.23941613
97Biosynthesis of amino acids_Homo sapiens_hsa012300.22843335
98Selenocompound metabolism_Homo sapiens_hsa004500.22432938
992-Oxocarboxylic acid metabolism_Homo sapiens_hsa012100.20804582
100Fat digestion and absorption_Homo sapiens_hsa049750.18600657

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