RPS20

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 40S subunit. The protein belongs to the S10P family of ribosomal proteins. It is located in the cytoplasm. This gene is co-transcribed with the small nucleolar RNA gene U54, which is located in its second intron. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome. Two transcript variants encoding different isoforms have been identified for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1* viral transcription (GO:0019083)9.41825592
2* translational termination (GO:0006415)9.06612302
3ribosomal small subunit biogenesis (GO:0042274)8.48604897
4ribosomal small subunit assembly (GO:0000028)8.42630001
5* translational elongation (GO:0006414)7.67483655
6* SRP-dependent cotranslational protein targeting to membrane (GO:0006614)7.60220210
7* protein targeting to ER (GO:0045047)7.45750137
8* cotranslational protein targeting to membrane (GO:0006613)7.45344586
9* establishment of protein localization to endoplasmic reticulum (GO:0072599)7.12907216
10* nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184)7.11588405
11* cellular protein complex disassembly (GO:0043624)7.01964127
12* viral life cycle (GO:0019058)7.00098683
13maturation of SSU-rRNA (GO:0030490)6.95461229
14* protein localization to endoplasmic reticulum (GO:0070972)6.94413645
15* translational initiation (GO:0006413)6.70810892
16ribosomal large subunit biogenesis (GO:0042273)6.40700775
17* protein complex disassembly (GO:0043241)6.14722617
18mitochondrial ATP synthesis coupled proton transport (GO:0042776)6.01283216
19* macromolecular complex disassembly (GO:0032984)5.74150094
20ATP synthesis coupled proton transport (GO:0015986)5.49782190
21energy coupled proton transport, down electrochemical gradient (GO:0015985)5.49782190
22* nuclear-transcribed mRNA catabolic process (GO:0000956)5.06243072
23* protein targeting to membrane (GO:0006612)4.97262389
24* mRNA catabolic process (GO:0006402)4.81054224
25ribonucleoprotein complex biogenesis (GO:0022613)4.79318885
26* translation (GO:0006412)4.62195334
27* RNA catabolic process (GO:0006401)4.51871521
28establishment of protein localization to mitochondrial membrane (GO:0090151)4.13353016
29formation of translation preinitiation complex (GO:0001731)3.88665669
30rRNA processing (GO:0006364)3.76667194
31respiratory electron transport chain (GO:0022904)3.75820368
32DNA strand elongation involved in DNA replication (GO:0006271)3.67700384
33chaperone-mediated protein transport (GO:0072321)3.66127487
34electron transport chain (GO:0022900)3.64664474
35rRNA metabolic process (GO:0016072)3.62825569
36telomere maintenance via semi-conservative replication (GO:0032201)3.58573486
37DNA strand elongation (GO:0022616)3.47780060
38cellular component biogenesis (GO:0044085)3.40987786
39mitochondrial electron transport, NADH to ubiquinone (GO:0006120)3.37880590
40DNA unwinding involved in DNA replication (GO:0006268)3.37020801
41ncRNA 3-end processing (GO:0043628)3.32418572
42protein localization to kinetochore (GO:0034501)3.32225880
43DNA replication initiation (GO:0006270)3.29290762
44* establishment of protein localization to membrane (GO:0090150)3.28484907
45DNA deamination (GO:0045006)3.24227813
46folic acid-containing compound biosynthetic process (GO:0009396)3.23472140
47negative regulation of RNA splicing (GO:0033119)3.19151444
48telomere maintenance via recombination (GO:0000722)3.14290248
49* establishment of protein localization to organelle (GO:0072594)3.05844845
50mitotic recombination (GO:0006312)3.02045833
51spliceosomal snRNP assembly (GO:0000387)3.00409723
52* protein targeting (GO:0006605)2.99296292
53chromatin remodeling at centromere (GO:0031055)2.98352612
54CENP-A containing nucleosome assembly (GO:0034080)2.97299744
55protein localization to chromosome, centromeric region (GO:0071459)2.96086817
56kinetochore organization (GO:0051383)2.93814197
57telomere maintenance via telomere lengthening (GO:0010833)2.93165553
58oxidative phosphorylation (GO:0006119)2.92727039
59inner mitochondrial membrane organization (GO:0007007)2.91375969
60DNA replication-dependent nucleosome assembly (GO:0006335)2.90540263
61DNA replication-dependent nucleosome organization (GO:0034723)2.90540263
62DNA replication checkpoint (GO:0000076)2.87120430
63mitotic nuclear envelope disassembly (GO:0007077)2.83063492
64ribosome biogenesis (GO:0042254)2.82729238
65spliceosomal complex assembly (GO:0000245)2.81355836
66mitotic chromosome condensation (GO:0007076)2.75585683
67nucleotide-excision repair, DNA gap filling (GO:0006297)2.73953162
68ATP biosynthetic process (GO:0006754)2.73744901
69DNA replication-independent nucleosome organization (GO:0034724)2.72061638
70DNA replication-independent nucleosome assembly (GO:0006336)2.72061638
71* cellular component disassembly (GO:0022411)2.68271253
72myeloid cell homeostasis (GO:0002262)2.64341694
73mitotic metaphase plate congression (GO:0007080)2.63282457
74nuclear envelope disassembly (GO:0051081)2.60002995
75membrane disassembly (GO:0030397)2.60002995
76negative regulation of DNA repair (GO:0045738)2.59668883
77kinetochore assembly (GO:0051382)2.59201385
78negative regulation of mRNA splicing, via spliceosome (GO:0048025)2.58767972
79purine ribonucleoside triphosphate biosynthetic process (GO:0009206)2.57915950
80ribosome assembly (GO:0042255)2.56598338
81IMP biosynthetic process (GO:0006188)2.56460671
82ncRNA processing (GO:0034470)2.55796540
83pyrimidine deoxyribonucleotide catabolic process (GO:0009223)2.55642297
84* gene expression (GO:0010467)2.55281691
85DNA topological change (GO:0006265)2.55264950
86regulation of transcription involved in G1/S transition of mitotic cell cycle (GO:0000083)2.54051129
87transcription elongation from RNA polymerase III promoter (GO:0006385)2.53376048
88termination of RNA polymerase III transcription (GO:0006386)2.53376048
89purine nucleoside triphosphate biosynthetic process (GO:0009145)2.52643325
90RNA splicing, via transesterification reactions (GO:0000375)2.52438571
91RNA splicing, via transesterification reactions with bulged adenosine as nucleophile (GO:0000377)2.51919866
92mRNA splicing, via spliceosome (GO:0000398)2.51919866
93establishment of integrated proviral latency (GO:0075713)2.51902012
94pseudouridine synthesis (GO:0001522)2.51751851
95nucleobase biosynthetic process (GO:0046112)2.50327267
96regulation of mitochondrial translation (GO:0070129)2.49761545
97termination of RNA polymerase II transcription (GO:0006369)2.49609730
98heterochromatin organization (GO:0070828)2.46229211
99nuclear pore organization (GO:0006999)2.45147563
100regulation of protein heterodimerization activity (GO:0043497)2.44860490
101regulation of translational fidelity (GO:0006450)2.44715400
102ribonucleoside triphosphate biosynthetic process (GO:0009201)2.44515071
103aerobic respiration (GO:0009060)2.44248395
104* protein localization to membrane (GO:0072657)2.42822520
105ribonucleoprotein complex assembly (GO:0022618)2.41250740
106regulation of mitotic spindle organization (GO:0060236)2.40258340
107regulation of spindle organization (GO:0090224)2.39573350
108exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay 2.38179179
109histone mRNA metabolic process (GO:0008334)2.37944703
110mitotic sister chromatid segregation (GO:0000070)2.37166028
111metaphase plate congression (GO:0051310)2.36873186
112transcription-coupled nucleotide-excision repair (GO:0006283)2.35646842
113nuclear pore complex assembly (GO:0051292)2.34515762
114histone exchange (GO:0043486)2.34141850
115innate immune response in mucosa (GO:0002227)2.33949118
116negative regulation of mRNA processing (GO:0050686)2.33494220
117ncRNA metabolic process (GO:0034660)2.33386032
118IMP metabolic process (GO:0046040)2.33066159
119protein targeting to mitochondrion (GO:0006626)2.32123747
120nuclear envelope reassembly (GO:0031468)2.31976469
121mitotic nuclear envelope reassembly (GO:0007084)2.31976469
122* protein localization to organelle (GO:0033365)2.31958019
123chromatin assembly or disassembly (GO:0006333)2.31418207
124mitochondrial respiratory chain complex I biogenesis (GO:0097031)2.31201561
125mitochondrial respiratory chain complex I assembly (GO:0032981)2.31201561
126NADH dehydrogenase complex assembly (GO:0010257)2.31201561
127* single-organism cellular localization (GO:1902580)2.31146448
128DNA-templated transcription, termination (GO:0006353)2.29797896
129ribonucleoprotein complex subunit organization (GO:0071826)2.27717440
130establishment of viral latency (GO:0019043)2.27505227
131pyrimidine nucleotide catabolic process (GO:0006244)2.26581295
132protein complex biogenesis (GO:0070271)2.25744841
133mitochondrial respiratory chain complex assembly (GO:0033108)2.25596306
134establishment of protein localization to mitochondrion (GO:0072655)2.23882097
135viral protein processing (GO:0019082)2.22538086
136UTP biosynthetic process (GO:0006228)2.21441431

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1E2F7_22180533_ChIP-Seq_HELA_Human6.98731706
2* MYC_18555785_ChIP-Seq_MESCs_Mouse4.66763263
3EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse3.72401116
4FOXM1_23109430_ChIP-Seq_U2OS_Human3.66724634
5MYC_19079543_ChIP-ChIP_MESCs_Mouse3.52189489
6E2F4_17652178_ChIP-ChIP_JURKAT_Human3.27723220
7SOX9_22984422_ChIP-ChIP_TESTIS_Rat3.25055294
8FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human2.96117496
9EST1_17652178_ChIP-ChIP_JURKAT_Human2.77937422
10* MYC_19030024_ChIP-ChIP_MESCs_Mouse2.72243320
11* MYC_18358816_ChIP-ChIP_MESCs_Mouse2.71032617
12* XRN2_22483619_ChIP-Seq_HELA_Human2.66055482
13* GABP_17652178_ChIP-ChIP_JURKAT_Human2.61838241
14* ETS1_20019798_ChIP-Seq_JURKAT_Human2.61207621
15KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human2.45213556
16TP63_17297297_ChIP-ChIP_HaCaT_Human2.39302785
17* CREB1_15753290_ChIP-ChIP_HEK293T_Human2.38199451
18HCFC1_20581084_ChIP-Seq_MESCs_Mouse2.34583534
19CHD1_19587682_ChIP-ChIP_MESCs_Mouse2.27078706
20TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat2.20610502
21* NELFA_20434984_ChIP-Seq_ESCs_Mouse2.15794960
22* TTF2_22483619_ChIP-Seq_HELA_Human2.14606125
23JARID1A_20064375_ChIP-Seq_MESCs_Mouse2.13697928
24* VDR_23849224_ChIP-Seq_CD4+_Human2.11479558
25ELF1_17652178_ChIP-ChIP_JURKAT_Human2.00477825
26* DCP1A_22483619_ChIP-Seq_HELA_Human1.98924621
27EGR1_19374776_ChIP-ChIP_THP-1_Human1.98845861
28SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse1.95992407
29* TAL1_20887958_ChIP-Seq_HPC-7_Mouse1.95259025
30* E2F1_18555785_ChIP-Seq_MESCs_Mouse1.88892007
31MYC_22102868_ChIP-Seq_BL_Human1.88045715
32RBPJ_22232070_ChIP-Seq_NCS_Mouse1.87401447
33* FOXP3_21729870_ChIP-Seq_TREG_Human1.87151406
34* ELK1_19687146_ChIP-ChIP_HELA_Human1.79937028
35MYBL2_22936984_ChIP-ChIP_MESCs_Mouse1.78476693
36HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human1.60650248
37MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse1.59534169
38* E2F1_21310950_ChIP-Seq_MCF-7_Human1.59044407
39NOTCH1_17114293_ChIP-ChIP_T-ALL_Human1.57601366
40POU5F1_18555785_ChIP-Seq_MESCs_Mouse1.56651971
41AR_21909140_ChIP-Seq_LNCAP_Human1.55646910
42VDR_21846776_ChIP-Seq_THP-1_Human1.55470177
43MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.52284207
44FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse1.51574909
45* GABP_19822575_ChIP-Seq_HepG2_Human1.48621228
46HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse1.47636884
47NANOG_18555785_ChIP-Seq_MESCs_Mouse1.46175535
48HOXB4_20404135_ChIP-ChIP_EML_Mouse1.43228488
49SPI1_22096565_ChIP-ChIP_GC-B_Mouse1.43078643
50* MYCN_18555785_ChIP-Seq_MESCs_Mouse1.43064963
51STAT3_1855785_ChIP-Seq_MESCs_Mouse1.41623180
52ZFP42_18358816_ChIP-ChIP_MESCs_Mouse1.40354444
53* ZFX_18555785_ChIP-Seq_MESCs_Mouse1.39785589
54* KLF4_19030024_ChIP-ChIP_MESCs_Mouse1.39620626
55CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human1.37178230
56FLI1_20887958_ChIP-Seq_HPC-7_Mouse1.36402926
57PDX1_19855005_ChIP-ChIP_MIN6_Mouse1.35512819
58ERG_20887958_ChIP-Seq_HPC-7_Mouse1.33992060
59SFPI1_20887958_ChIP-Seq_HPC-7_Mouse1.33484801
60FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse1.32436324
61SMAD1_18555785_ChIP-Seq_MESCs_Mouse1.31528916
62NOTCH1_21737748_ChIP-Seq_TLL_Human1.31321748
63TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse1.31075425
64CIITA_25753668_ChIP-Seq_RAJI_Human1.31025811
65KDM5A_27292631_Chip-Seq_BREAST_Human1.25748958
66ASXL1_24218140_ChIP-Seq_BMDM_Mouse1.24850795
67ELK1_22589737_ChIP-Seq_MCF10A_Human1.24418413
68* THAP11_20581084_ChIP-Seq_MESCs_Mouse1.23930463
69KLF2_18264089_ChIP-ChIP_MESCs_Mouse1.19573385
70KLF5_18264089_ChIP-ChIP_MESCs_Mouse1.19573385
71KLF4_18264089_ChIP-ChIP_MESCs_Mouse1.19573385
72KLF4_18555785_ChIP-Seq_MESCs_Mouse1.17122386
73KLF4_18358816_ChIP-ChIP_MESCs_Mouse1.16788553
74CCND1_20090754_ChIP-ChIP_RETINA_Mouse1.15530100
75SPI1_23547873_ChIP-Seq_NB4_Human1.14145143
76DACH1_20351289_ChIP-Seq_MDA-MB-231_Human1.13342128
77* CEBPB_24764292_ChIP-Seq_MC3T3_Mouse1.13064419
78BCL3_23251550_ChIP-Seq_MUSCLE_Mouse1.12674432
79* POU5F1_18358816_ChIP-ChIP_MESCs_Mouse1.12654982
80POU5F1_18700969_ChIP-ChIP_MESCs_Mouse1.12095132
81YY1_21170310_ChIP-Seq_MESCs_Mouse1.10192602
82SOX2_18555785_ChIP-Seq_MESCs_Mouse1.09538645
83PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse1.08890795
84SOX2_19030024_ChIP-ChIP_MESCs_Mouse1.08658485
85MYC_18940864_ChIP-ChIP_HL60_Human1.07768686
86TCF3_18692474_ChIP-Seq_MEFs_Mouse1.06411099
87* CTCF_18555785_ChIP-Seq_MESCs_Mouse1.05261017
88SOX2_16153702_ChIP-ChIP_HESCs_Human1.05238404
89HSF1_23293686_ChIP-Seq_STHDH_STRIATAL_Mouse1.04072703
90TFEB_21752829_ChIP-Seq_HELA_Human1.02764405
91YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.00390376
92* IRF8_22096565_ChIP-ChIP_GC-B_Mouse0.99939127
93TP63_19390658_ChIP-ChIP_HaCaT_Human0.98963827
94PPARG_19300518_ChIP-PET_3T3-L1_Mouse0.98767555
95UTX_26944678_Chip-Seq_JUKART_Human0.97886492
96* CNOT3_19339689_ChIP-ChIP_MESCs_Mouse0.97824986
97MAF_26560356_Chip-Seq_TH1_Human0.97553921
98KDM5B_21448134_ChIP-Seq_MESCs_Mouse0.96633270
99CUX1_19635798_ChIP-ChIP_MULTIPLE_HUMAN_CANCER_TYPES_Human0.96005108
100E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse0.94139799
101E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human0.93936843
102* ASH2L_23239880_ChIP-Seq_MESCs_Mouse0.92559213
103PADI4_21655091_ChIP-ChIP_MCF-7_Human0.92223856
104TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse0.91976843
105ESR1_15608294_ChIP-ChIP_MCF-7_Human0.91811854
106MAF_26560356_Chip-Seq_TH2_Human0.91587350
107SRF_21415370_ChIP-Seq_HL-1_Mouse0.91031053
108GFI1B_20887958_ChIP-Seq_HPC-7_Mouse0.89616667
109* OCT4_18692474_ChIP-Seq_MEFs_Mouse0.88028844
110SOX2_18692474_ChIP-Seq_MEFs_Mouse0.86753124
111ZNF263_19887448_ChIP-Seq_K562_Human0.86033300
112SRY_22984422_ChIP-ChIP_TESTIS_Rat0.85153497
113TET1_21451524_ChIP-Seq_MESCs_Mouse0.84653997
114* FOXP1_21924763_ChIP-Seq_HESCs_Human0.81614002
115NANOG_21062744_ChIP-ChIP_HESCs_Human0.81402333

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0006292_abnormal_olfactory_placode4.34458693
2MP0003693_abnormal_embryo_hatching4.02356521
3MP0004957_abnormal_blastocyst_morpholog3.60750705
4MP0010094_abnormal_chromosome_stability3.08938436
5MP0003111_abnormal_nucleus_morphology2.95931896
6MP0003077_abnormal_cell_cycle2.89930753
7MP0008007_abnormal_cellular_replicative2.44199175
8MP0008057_abnormal_DNA_replication2.33535225
9MP0000566_synostosis2.22326465
10MP0002396_abnormal_hematopoietic_system2.17507840
11MP0008932_abnormal_embryonic_tissue2.16127145
12MP0008995_early_reproductive_senescence2.10379621
13MP0003941_abnormal_skin_development1.97120168
14MP0010352_gastrointestinal_tract_polyps1.95700923
15MP0000490_abnormal_crypts_of1.94302003
16MP0008058_abnormal_DNA_repair1.92203613
17MP0003186_abnormal_redox_activity1.87990340
18MP0000350_abnormal_cell_proliferation1.78765480
19MP0010030_abnormal_orbit_morphology1.75818082
20MP0003763_abnormal_thymus_physiology1.75626064
21MP0002697_abnormal_eye_size1.68816630
22MP0003786_premature_aging1.68040166
23MP0001286_abnormal_eye_development1.63320916
24MP0004808_abnormal_hematopoietic_stem1.61089333
25MP0009333_abnormal_splenocyte_physiolog1.59655280
26MP0001730_embryonic_growth_arrest1.54850385
27MP0003303_peritoneal_inflammation1.51622082
28* MP0009379_abnormal_foot_pigmentation1.48379324
29MP0002009_preneoplasia1.47097412
30MP0000537_abnormal_urethra_morphology1.44938176
31MP0000049_abnormal_middle_ear1.44151192
32MP0003938_abnormal_ear_development1.42499717
33MP0005408_hypopigmentation1.40282117
34MP0008789_abnormal_olfactory_epithelium1.38256131
35MP0003890_abnormal_embryonic-extraembry1.36071065
36MP0000372_irregular_coat_pigmentation1.32286505
37MP0002210_abnormal_sex_determination1.31021891
38MP0000703_abnormal_thymus_morphology1.30394836
39MP0002019_abnormal_tumor_incidence1.30086414
40MP0005076_abnormal_cell_differentiation1.29842177
41MP0002398_abnormal_bone_marrow1.29364560
42MP0006054_spinal_hemorrhage1.28070559
43MP0001697_abnormal_embryo_size1.27737279
44MP0003567_abnormal_fetal_cardiomyocyte1.26161882
45MP0000685_abnormal_immune_system1.26142507
46MP0010307_abnormal_tumor_latency1.24785384
47MP0003123_paternal_imprinting1.24555315
48MP0002277_abnormal_respiratory_mucosa1.24346080
49MP0005501_abnormal_skin_physiology1.22891504
50MP0000858_altered_metastatic_potential1.22468999
51MP0002722_abnormal_immune_system1.21318657
52MP0002092_abnormal_eye_morphology1.20186820
53MP0005499_abnormal_olfactory_system1.19726887
54MP0005394_taste/olfaction_phenotype1.19726887
55* MP0002080_prenatal_lethality1.18322114
56MP0001800_abnormal_humoral_immune1.17771126
57MP0000750_abnormal_muscle_regeneration1.16786672
58MP0005174_abnormal_tail_pigmentation1.16742540
59MP0002085_abnormal_embryonic_tissue1.15914612
60MP0001672_abnormal_embryogenesis/_devel1.15580650
61MP0005380_embryogenesis_phenotype1.15580650
62MP0000313_abnormal_cell_death1.15290016
63MP0001545_abnormal_hematopoietic_system1.13501420
64MP0005397_hematopoietic_system_phenotyp1.13501420
65MP0000689_abnormal_spleen_morphology1.11050655
66MP0002084_abnormal_developmental_patter1.09568741
67MP0002166_altered_tumor_susceptibility1.08756155
68MP0002086_abnormal_extraembryonic_tissu1.08605226
69MP0005666_abnormal_adipose_tissue1.07475219
70MP0009053_abnormal_anal_canal1.07001872
71MP0002796_impaired_skin_barrier1.06757647
72MP0008438_abnormal_cutaneous_collagen1.06714678
73MP0002088_abnormal_embryonic_growth/wei1.05555928
74MP0000428_abnormal_craniofacial_morphol1.05413005
75MP0004197_abnormal_fetal_growth/weight/1.05010519
76MP0003984_embryonic_growth_retardation1.04731443
77MP0005023_abnormal_wound_healing1.04491702
78MP0003566_abnormal_cell_adhesion1.04481270
79MP0003718_maternal_effect1.04303254
80MP0003436_decreased_susceptibility_to1.02814190
81MP0001346_abnormal_lacrimal_gland1.02723504
82MP0001145_abnormal_male_reproductive1.02667087
83MP0002429_abnormal_blood_cell1.01774304
84MP0001835_abnormal_antigen_presentation1.01282154
85MP0002452_abnormal_antigen_presenting0.99563848
86MP0009672_abnormal_birth_weight0.99524526
87MP0002420_abnormal_adaptive_immunity0.98598920
88MP0002132_abnormal_respiratory_system0.98123865
89MP0002006_tumorigenesis0.97638292
90MP0002060_abnormal_skin_morphology0.97415352
91MP0000716_abnormal_immune_system0.96853214
92MP0003283_abnormal_digestive_organ0.96828378
93MP0001819_abnormal_immune_cell0.96610342
94MP0000762_abnormal_tongue_morphology0.94994067
95MP0010155_abnormal_intestine_physiology0.94774910
96MP0003828_pulmonary_edema0.94661400
97MP0005075_abnormal_melanosome_morpholog0.93823200
98MP0000631_abnormal_neuroendocrine_gland0.93206630
99MP0003136_yellow_coat_color0.92706483
100MP0003959_abnormal_lean_body0.92175951
101MP0003453_abnormal_keratinocyte_physiol0.92094717
102MP0003937_abnormal_limbs/digits/tail_de0.90573984
103MP0003724_increased_susceptibility_to0.90279200
104MP0000465_gastrointestinal_hemorrhage0.89877705
105MP0002405_respiratory_system_inflammati0.89084981
106MP0001881_abnormal_mammary_gland0.88992142
107MP0004381_abnormal_hair_follicle0.87565567
108MP0005275_abnormal_skin_tensile0.87490092
109MP0004185_abnormal_adipocyte_glucose0.87297925
110MP0002723_abnormal_immune_serum0.86832903
111MP0002233_abnormal_nose_morphology0.86332608
112MP0005000_abnormal_immune_tolerance0.85905840
113MP0002111_abnormal_tail_morphology0.85680799
114MP0001216_abnormal_epidermal_layer0.85579415
115MP0001293_anophthalmia0.83803718
116MP0005671_abnormal_response_to0.83448983
117MP0003300_gastrointestinal_ulcer0.82947692
118MP0001929_abnormal_gametogenesis0.82122900
119MP0003448_altered_tumor_morphology0.81509049
120MP0009278_abnormal_bone_marrow0.81224075
121MP0001243_abnormal_dermal_layer0.81220296
122MP0003705_abnormal_hypodermis_morpholog0.80846803
123MP0003315_abnormal_perineum_morphology0.80458878
124MP0002163_abnormal_gland_morphology0.80069694
125MP0002653_abnormal_ependyma_morphology0.79987059
126MP0001853_heart_inflammation0.79631161
127MP0000653_abnormal_sex_gland0.78665216
128MP0002160_abnormal_reproductive_system0.78170365
129MP0003878_abnormal_ear_physiology0.77968053
130MP0005377_hearing/vestibular/ear_phenot0.77968053
131MP0005025_abnormal_response_to0.77851386
132MP0005503_abnormal_tendon_morphology0.77411321
133MP0003806_abnormal_nucleotide_metabolis0.77363176
134MP0002249_abnormal_larynx_morphology0.76496302
135MP0002877_abnormal_melanocyte_morpholog0.76053006
136MP0002638_abnormal_pupillary_reflex0.75507971
137MP0002098_abnormal_vibrissa_morphology0.75283390
138MP0006036_abnormal_mitochondrial_physio0.75230618
139MP0000613_abnormal_salivary_gland0.74551824
140MP0002282_abnormal_trachea_morphology0.74378212
141MP0002148_abnormal_hypersensitivity_rea0.74215724
142MP0000477_abnormal_intestine_morphology0.73743094
143MP0001873_stomach_inflammation0.73300110
144MP0001348_abnormal_lacrimal_gland0.73257060
145MP0009697_abnormal_copulation0.72339022
146MP0005389_reproductive_system_phenotype0.72176499
147MP0001919_abnormal_reproductive_system0.71727245
148MP0002938_white_spotting0.71245651
149MP0005379_endocrine/exocrine_gland_phen0.69904587
150MP0008961_abnormal_basal_metabolism0.69680354
151MP0009250_abnormal_appendicular_skeleto0.68380191
152MP0001529_abnormal_vocalization0.66312650
153MP0005381_digestive/alimentary_phenotyp0.66177162

Predicted human phenotypes

RankGene SetZ-score
1Reticulocytopenia (HP:0001896)8.11760210
2Abnormality of cells of the erythroid lineage (HP:0012130)7.69326986
3Abnormal number of erythroid precursors (HP:0012131)6.89728950
4Macrocytic anemia (HP:0001972)5.90556672
5Pallor (HP:0000980)5.49611814
6Abnormal hemoglobin (HP:0011902)4.35803897
7Lipid accumulation in hepatocytes (HP:0006561)4.00798947
8Acute necrotizing encephalopathy (HP:0006965)3.75053880
9Colon cancer (HP:0003003)3.69352089
10Aplasia/Hypoplasia of the sacrum (HP:0008517)3.67517938
11Thrombocytosis (HP:0001894)3.55995923
12Septo-optic dysplasia (HP:0100842)3.48427970
13Mitochondrial inheritance (HP:0001427)3.47705612
14Abnormal mitochondria in muscle tissue (HP:0008316)3.41116619
15Renal Fanconi syndrome (HP:0001994)3.24130728
16Acute encephalopathy (HP:0006846)3.19161011
17Increased intramyocellular lipid droplets (HP:0012240)3.18548804
18Respiratory difficulties (HP:0002880)3.13654589
19Congenital, generalized hypertrichosis (HP:0004540)2.96794554
20Absent thumb (HP:0009777)2.95125288
21Trismus (HP:0000211)2.93425867
2211 pairs of ribs (HP:0000878)2.91542831
23Maternal diabetes (HP:0009800)2.85046574
24Increased CSF lactate (HP:0002490)2.84744782
25Progressive macrocephaly (HP:0004481)2.82289175
26Increased muscle lipid content (HP:0009058)2.80266841
27Abnormality of reticulocytes (HP:0004312)2.79760538
28Hepatocellular necrosis (HP:0001404)2.76876325
29Abnormality of the parietal bone (HP:0002696)2.76793417
30Aplastic anemia (HP:0001915)2.70298360
31Depressed nasal ridge (HP:0000457)2.67192556
32Oral leukoplakia (HP:0002745)2.64454233
33Breast hypoplasia (HP:0003187)2.57801375
34Selective tooth agenesis (HP:0001592)2.49616154
35Duplication of thumb phalanx (HP:0009942)2.44231429
36Cerebral edema (HP:0002181)2.44165045
37Triphalangeal thumb (HP:0001199)2.42499552
38Rough bone trabeculation (HP:0100670)2.40921636
39Multiple enchondromatosis (HP:0005701)2.37030899
403-Methylglutaconic aciduria (HP:0003535)2.34731545
41Hepatic necrosis (HP:0002605)2.33848647
42Thick lower lip vermilion (HP:0000179)2.29461912
43Birth length less than 3rd percentile (HP:0003561)2.27049797
44Missing ribs (HP:0000921)2.23180756
45Microvesicular hepatic steatosis (HP:0001414)2.23067713
46Absent septum pellucidum (HP:0001331)2.22865141
47Woolly hair (HP:0002224)2.19579629
48Rib fusion (HP:0000902)2.18080634
49Basal cell carcinoma (HP:0002671)2.16255698
50Nasolacrimal duct obstruction (HP:0000579)2.15731106
51Migraine (HP:0002076)2.15116062
52Protrusio acetabuli (HP:0003179)2.13472021
53Sparse lateral eyebrow (HP:0005338)2.13319544
54Atresia of the external auditory canal (HP:0000413)2.10456085
55Myelodysplasia (HP:0002863)2.09941782
56Abnormality of the septum pellucidum (HP:0007375)2.09474935
57Asplenia (HP:0001746)2.07915078
58Neoplasm of the pancreas (HP:0002894)2.00788090
59Hypoplasia of the radius (HP:0002984)1.99561899
60Exercise intolerance (HP:0003546)1.99539620
61IgM deficiency (HP:0002850)1.96169176
62Carpal bone hypoplasia (HP:0001498)1.95396885
63Glossoptosis (HP:0000162)1.95324285
64Abnormality of the preputium (HP:0100587)1.94802076
65Abnormality of renal resorption (HP:0011038)1.93728023
66Stenosis of the external auditory canal (HP:0000402)1.93385138
67Exertional dyspnea (HP:0002875)1.92432043
68Cleft eyelid (HP:0000625)1.91345891
69Premature rupture of membranes (HP:0001788)1.90999424
70Leukodystrophy (HP:0002415)1.88786010
71Sparse eyelashes (HP:0000653)1.88641479
72Rhabdomyosarcoma (HP:0002859)1.88508659
73Aplasia/Hypoplasia of the spleen (HP:0010451)1.87429749
74Abnormality of the lacrimal duct (HP:0011481)1.86997609
75Chromosomal breakage induced by crosslinking agents (HP:0003221)1.85624927
76Patellar aplasia (HP:0006443)1.84717859
77Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688)1.84648488
78Hyperphosphaturia (HP:0003109)1.81789797
79Meckel diverticulum (HP:0002245)1.78531702
80Down-sloping shoulders (HP:0200021)1.78503890
81Chromsome breakage (HP:0040012)1.77828275
82Partial duplication of the phalanx of hand (HP:0009999)1.76958484
83Proximal placement of thumb (HP:0009623)1.76782114
84Premature graying of hair (HP:0002216)1.76494049
85Lactic acidosis (HP:0003128)1.75208453
86Absent radius (HP:0003974)1.74853306
87Increased hepatocellular lipid droplets (HP:0006565)1.74296814
88Aplasia/Hypoplasia of the patella (HP:0006498)1.73804153
89Abdominal situs inversus (HP:0003363)1.73509711
90Abnormality of abdominal situs (HP:0011620)1.73509711
91Entropion (HP:0000621)1.73296029
92Increased density of long bones (HP:0006392)1.72723926
93Microretrognathia (HP:0000308)1.71868040
94Abnormal number of incisors (HP:0011064)1.71840743
95Abnormal activity of mitochondrial respiratory chain (HP:0011922)1.71349076
96Decreased activity of mitochondrial respiratory chain (HP:0008972)1.71349076
97Abnormality of the ileum (HP:0001549)1.70175448
98Respiratory failure (HP:0002878)1.69915533
99Abnormality of chromosome stability (HP:0003220)1.69504908
100Tracheoesophageal fistula (HP:0002575)1.69229622
101Abnormal trabecular bone morphology (HP:0100671)1.69123746
102Abnormality of the nasolacrimal system (HP:0000614)1.68644303
103Squamous cell carcinoma (HP:0002860)1.68304712
104Concave nail (HP:0001598)1.68094972
105Horseshoe kidney (HP:0000085)1.67698711
106Lymphoma (HP:0002665)1.67264787
107Increased serum lactate (HP:0002151)1.66444579
108Deviation of the thumb (HP:0009603)1.66011461
109Progressive muscle weakness (HP:0003323)1.65530169
110Cellular immunodeficiency (HP:0005374)1.65034999
111Secondary amenorrhea (HP:0000869)1.64773381
112Rectal prolapse (HP:0002035)1.64279677
113Aplasia/Hypoplasia of the thymus (HP:0010515)1.64097814
114Amaurosis fugax (HP:0100576)1.63840911
115Recurrent bronchitis (HP:0002837)1.59800822
116Poikiloderma (HP:0001029)1.58958626
117Broad distal phalanx of finger (HP:0009836)1.58925239
118Colitis (HP:0002583)1.58823426
119Short nose (HP:0003196)1.58802073
120Medulloblastoma (HP:0002885)1.58092440
121Aplasia involving forearm bones (HP:0009822)1.57936543
122Absent forearm bone (HP:0003953)1.57936543
123Cellulitis (HP:0100658)1.55265533
124Dysphonia (HP:0001618)1.55047070
125Optic disc pallor (HP:0000543)1.54614114
126Abnormal urine phosphate concentration (HP:0012599)1.54516151
127Facial cleft (HP:0002006)1.53230276
128Bilateral microphthalmos (HP:0007633)1.52811894
129Abnormality of the anterior horn cell (HP:0006802)1.52386318
130Degeneration of anterior horn cells (HP:0002398)1.52386318
131Panhypogammaglobulinemia (HP:0003139)1.50911704
132Short middle phalanx of the 5th finger (HP:0004220)1.50691394
133Progressive external ophthalmoplegia (HP:0000590)1.50582730
134Acute lymphatic leukemia (HP:0006721)1.49760663
135Duplicated collecting system (HP:0000081)1.49127301
136Sparse scalp hair (HP:0002209)1.48891720
137Elevated erythrocyte sedimentation rate (HP:0003565)1.48863243
138Partial duplication of thumb phalanx (HP:0009944)1.48429098
139Neoplasm of the colon (HP:0100273)1.48343786
140Thoracic kyphosis (HP:0002942)1.48093485
141Aplasia/Hypoplasia of the uvula (HP:0010293)1.47909686
142Pancytopenia (HP:0001876)1.47130207
143Diastasis recti (HP:0001540)1.46605762
144Supernumerary spleens (HP:0009799)1.45963094
145Muscle abnormality related to mitochondrial dysfunction (HP:0003800)1.44987042
146Small intestinal stenosis (HP:0012848)1.44726339
147Duodenal stenosis (HP:0100867)1.44726339
148Ependymoma (HP:0002888)1.44396388
149Soft skin (HP:0000977)1.43873005
150Esophageal atresia (HP:0002032)1.41909019
151Abnormality of DNA repair (HP:0003254)1.39369667
152Supernumerary ribs (HP:0005815)1.39043258
153Anophthalmia (HP:0000528)1.38026418
154Abnormality of cochlea (HP:0000375)1.36616711
155Forearm undergrowth (HP:0009821)1.34505906

Predicted kinase interactions (KEA)

RankGene SetZ-score
1NME24.69338216
2VRK23.68252238
3TLK13.55457520
4BUB13.20701919
5WEE13.19421765
6EIF2AK12.92250551
7EEF2K2.58847728
8RPS6KB22.41168881
9CDC72.32098570
10NEK22.11178474
11SRPK12.02378127
12LRRK21.98526391
13PIM21.91347504
14TGFBR11.78422170
15MAP4K11.78349739
16DYRK31.78213151
17TESK21.77347455
18VRK11.72231707
19ZAK1.70709945
20PKN21.70508916
21PRPF4B1.67243097
22CDK71.57447099
23PASK1.57398764
24RPS6KA41.56835583
25MKNK11.55616015
26TAF11.52747200
27FLT31.51102997
28AURKB1.50370664
29MAP3K101.48372151
30EPHB21.47693854
31STK101.40028839
32MST41.39998693
33STK161.36051636
34SMG11.34700641
35STK241.32846452
36EIF2AK31.32538976
37MKNK21.32488312
38TTK1.31698530
39PLK11.26881901
40PIM11.22554434
41ACVR1B1.21941049
42MAP3K81.19819168
43PAK41.14058304
44EPHA21.13007001
45TSSK61.10074293
46BRSK21.04998539
47BLK1.04211847
48CDK121.03821109
49CDK41.03059752
50DYRK21.01169256
51ATR1.00236647
52NEK90.98212713
53TEC0.95827672
54BTK0.92899538
55AURKA0.92307223
56STK40.92222173
57SCYL20.91993869
58MAPKAPK30.91251510
59NLK0.89300539
60TYRO30.88500040
61CDK60.86751490
62CLK10.86661717
63BRAF0.84465109
64ILK0.81262245
65ALK0.78459857
66CDK80.76810131
67IKBKB0.74844743
68CSNK2A20.73351511
69CHEK10.73077426
70MAPK150.72747331
71CDK90.72501844
72CHEK20.71759009
73ZAP700.71535890
74CDK190.71028846
75RPS6KA50.69393941
76SIK10.68428847
77KDR0.67292990
78GRK60.66721377
79TRIB30.65355286
80PNCK0.65289999
81DYRK1B0.64741140
82MAP3K110.61928148
83MAP2K30.60105496
84JAK30.59013749
85PAK20.58968816
86PAK10.57986018
87CSNK2A10.57983774
88PBK0.57756430
89ATM0.57222246
90TESK10.57043755
91NEK10.56645506
92EIF2AK20.55212159
93LATS20.54835475
94PLK40.53357209
95NME10.51706763
96PTK60.51632098
97DAPK30.51615706
98TYK20.51276700
99MELK0.51165750
100LCK0.50749703
101CDK20.50568068
102ABL20.48419997
103MARK30.48377711
104MAP3K30.48296665
105MAP3K130.48274679
106PLK30.47349099
107STK30.47265151
108BRSK10.46936556
109MAP2K20.45448423
110CSNK1E0.44976044
111KIT0.44675956
112CDK10.43601357
113RPS6KC10.43162150
114RPS6KL10.43162150
115RPS6KA10.40160351
116PRKCI0.39740024
117LYN0.38907973
118BMX0.38722659
119RPS6KA60.38489540
120FES0.37663366
121CSK0.36937120
122CDK30.36919054
123BRD40.36673785
124TBK10.35172520
125CSF1R0.34331008
126AKT10.31268683
127ITK0.26050707
128WNK40.25370759
129CDK11A0.24943461
130MTOR0.24398786
131AKT20.24189750
132MOS0.24128608
133FGFR10.23856738
134DMPK0.23380502

Predicted pathways (KEGG)

RankGene SetZ-score
1* Ribosome_Homo sapiens_hsa030107.22798176
2DNA replication_Homo sapiens_hsa030303.94947798
3Mismatch repair_Homo sapiens_hsa034303.28208790
4Spliceosome_Homo sapiens_hsa030403.05299454
5RNA polymerase_Homo sapiens_hsa030202.86511347
6Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030082.70861655
7Homologous recombination_Homo sapiens_hsa034402.56313207
8RNA transport_Homo sapiens_hsa030132.36843840
9One carbon pool by folate_Homo sapiens_hsa006702.35484884
10Nucleotide excision repair_Homo sapiens_hsa034202.34204840
11Base excision repair_Homo sapiens_hsa034102.33456741
12Proteasome_Homo sapiens_hsa030502.30797986
13Pyrimidine metabolism_Homo sapiens_hsa002402.11262269
14Cell cycle_Homo sapiens_hsa041101.93892492
15Cardiac muscle contraction_Homo sapiens_hsa042601.84345684
16Fanconi anemia pathway_Homo sapiens_hsa034601.70879532
17Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009701.56523513
18Non-homologous end-joining_Homo sapiens_hsa034501.54913037
19p53 signaling pathway_Homo sapiens_hsa041151.52542647
20Basal transcription factors_Homo sapiens_hsa030221.48573516
21Cytosolic DNA-sensing pathway_Homo sapiens_hsa046231.47373621
22Protein export_Homo sapiens_hsa030601.44966635
23RNA degradation_Homo sapiens_hsa030181.44899252
24Systemic lupus erythematosus_Homo sapiens_hsa053221.38723276
25mRNA surveillance pathway_Homo sapiens_hsa030151.33098519
26Primary immunodeficiency_Homo sapiens_hsa053401.23662193
27Cyanoamino acid metabolism_Homo sapiens_hsa004601.23236473
28Herpes simplex infection_Homo sapiens_hsa051681.15076797
29Epstein-Barr virus infection_Homo sapiens_hsa051691.13774299
30Antigen processing and presentation_Homo sapiens_hsa046121.08243455
31Sulfur relay system_Homo sapiens_hsa041221.06152565
32Viral carcinogenesis_Homo sapiens_hsa052030.93036481
33Purine metabolism_Homo sapiens_hsa002300.90146676
34Parkinsons disease_Homo sapiens_hsa050120.84514341
35HTLV-I infection_Homo sapiens_hsa051660.84313689
36Thyroid cancer_Homo sapiens_hsa052160.84047855
37Small cell lung cancer_Homo sapiens_hsa052220.83000418
38Transcriptional misregulation in cancer_Homo sapiens_hsa052020.79238695
39Huntingtons disease_Homo sapiens_hsa050160.77977844
40Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.74954546
41Hematopoietic cell lineage_Homo sapiens_hsa046400.74181582
42Folate biosynthesis_Homo sapiens_hsa007900.73760187
43Measles_Homo sapiens_hsa051620.71772919
44NF-kappa B signaling pathway_Homo sapiens_hsa040640.68184263
45Bladder cancer_Homo sapiens_hsa052190.67615897
46MicroRNAs in cancer_Homo sapiens_hsa052060.66980849
47Oxidative phosphorylation_Homo sapiens_hsa001900.65892249
48Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.65500875
49Apoptosis_Homo sapiens_hsa042100.64806929
50Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.62381415
51Basal cell carcinoma_Homo sapiens_hsa052170.62361726
52Acute myeloid leukemia_Homo sapiens_hsa052210.60077895
53Intestinal immune network for IgA production_Homo sapiens_hsa046720.59999961
54Chronic myeloid leukemia_Homo sapiens_hsa052200.59112129
55Legionellosis_Homo sapiens_hsa051340.57231788
56Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049320.56712540
57Hepatitis B_Homo sapiens_hsa051610.55856079
58TGF-beta signaling pathway_Homo sapiens_hsa043500.54999312
59Jak-STAT signaling pathway_Homo sapiens_hsa046300.54039460
60Pentose phosphate pathway_Homo sapiens_hsa000300.53600392
61Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.51295615
62Shigellosis_Homo sapiens_hsa051310.51229531
63B cell receptor signaling pathway_Homo sapiens_hsa046620.47332432
64Inflammatory bowel disease (IBD)_Homo sapiens_hsa053210.46064530
65Leishmaniasis_Homo sapiens_hsa051400.46044042
66Leukocyte transendothelial migration_Homo sapiens_hsa046700.45757487
67NOD-like receptor signaling pathway_Homo sapiens_hsa046210.45408918
68Alcoholism_Homo sapiens_hsa050340.43814914
69Pyruvate metabolism_Homo sapiens_hsa006200.43565310
70RIG-I-like receptor signaling pathway_Homo sapiens_hsa046220.43537695
71Viral myocarditis_Homo sapiens_hsa054160.43490015
72Autoimmune thyroid disease_Homo sapiens_hsa053200.43393146
73AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049330.42963834
74Notch signaling pathway_Homo sapiens_hsa043300.42398219
75Pathways in cancer_Homo sapiens_hsa052000.42215432
76Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.41551678
77Glutathione metabolism_Homo sapiens_hsa004800.41141761
78Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006300.40172710
79Colorectal cancer_Homo sapiens_hsa052100.39665296
80Hippo signaling pathway_Homo sapiens_hsa043900.39025160
81HIF-1 signaling pathway_Homo sapiens_hsa040660.38515038
82Cysteine and methionine metabolism_Homo sapiens_hsa002700.38099592
83Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.37375669
84Influenza A_Homo sapiens_hsa051640.36080179
85Toxoplasmosis_Homo sapiens_hsa051450.35854747
86Oocyte meiosis_Homo sapiens_hsa041140.35520086
87Metabolic pathways_Homo sapiens_hsa011000.34633553
88Allograft rejection_Homo sapiens_hsa053300.33762922
89Cytokine-cytokine receptor interaction_Homo sapiens_hsa040600.33414420
90T cell receptor signaling pathway_Homo sapiens_hsa046600.33306997
91Alzheimers disease_Homo sapiens_hsa050100.32196104
92Wnt signaling pathway_Homo sapiens_hsa043100.32048811
93Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046500.30927106
94Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046660.30658262
95Proteoglycans in cancer_Homo sapiens_hsa052050.30319250
96Asthma_Homo sapiens_hsa053100.29814296
97Malaria_Homo sapiens_hsa051440.29657379
98Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.29247056
99Prostate cancer_Homo sapiens_hsa052150.28146134
100ECM-receptor interaction_Homo sapiens_hsa045120.27514827
101Adherens junction_Homo sapiens_hsa045200.27027958
102Graft-versus-host disease_Homo sapiens_hsa053320.26401359
103N-Glycan biosynthesis_Homo sapiens_hsa005100.26239538
104Platelet activation_Homo sapiens_hsa046110.25320856
105Fc epsilon RI signaling pathway_Homo sapiens_hsa046640.24649385
106PI3K-Akt signaling pathway_Homo sapiens_hsa041510.23603382
107Hedgehog signaling pathway_Homo sapiens_hsa043400.23179688
108Drug metabolism - other enzymes_Homo sapiens_hsa009830.23034677
109Bacterial invasion of epithelial cells_Homo sapiens_hsa051000.22959951
110Biosynthesis of amino acids_Homo sapiens_hsa012300.22919518
111Renal cell carcinoma_Homo sapiens_hsa052110.19506730
112Carbon metabolism_Homo sapiens_hsa012000.18952241
113Pancreatic cancer_Homo sapiens_hsa052120.17238797
114Selenocompound metabolism_Homo sapiens_hsa004500.16153892
115Vitamin digestion and absorption_Homo sapiens_hsa049770.15483137
116Tyrosine metabolism_Homo sapiens_hsa003500.12938882
117Non-small cell lung cancer_Homo sapiens_hsa052230.11575755
118Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.07713102
119Melanoma_Homo sapiens_hsa052180.03668568
120Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001300.01052469
121Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.00342151
122Terpenoid backbone biosynthesis_Homo sapiens_hsa00900-0.0179476
123VEGF signaling pathway_Homo sapiens_hsa04370-0.0151702
124Citrate cycle (TCA cycle)_Homo sapiens_hsa00020-0.0089113

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