RPS17

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of four RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 40S subunit. The protein belongs to the S17E family of ribosomal proteins and is located in the cytoplasm. Mutations in this gene cause Diamond-Blackfan anemia 4. Alternative splicing of this gene results in multiple transcript variants. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1* viral transcription (GO:0019083)9.29917772
2* translational termination (GO:0006415)8.96148291
3* ribosomal small subunit assembly (GO:0000028)8.06050045
4* ribosomal small subunit biogenesis (GO:0042274)7.96249495
5* translational elongation (GO:0006414)7.71138816
6* SRP-dependent cotranslational protein targeting to membrane (GO:0006614)7.59307360
7* protein targeting to ER (GO:0045047)7.43681627
8* cotranslational protein targeting to membrane (GO:0006613)7.43363800
9* establishment of protein localization to endoplasmic reticulum (GO:0072599)7.10680555
10* nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184)7.08018575
11maturation of SSU-rRNA (GO:0030490)6.95811227
12* cellular protein complex disassembly (GO:0043624)6.94781826
13* protein localization to endoplasmic reticulum (GO:0070972)6.94246601
14* viral life cycle (GO:0019058)6.92751068
15* translational initiation (GO:0006413)6.73217179
16* protein complex disassembly (GO:0043241)6.14125306
17ribosomal large subunit biogenesis (GO:0042273)6.07400843
18* macromolecular complex disassembly (GO:0032984)5.72291116
19* nuclear-transcribed mRNA catabolic process (GO:0000956)5.09258033
20* protein targeting to membrane (GO:0006612)4.91929938
21* mRNA catabolic process (GO:0006402)4.82615230
22* translation (GO:0006412)4.79889508
23* ribonucleoprotein complex biogenesis (GO:0022613)4.71267769
24* RNA catabolic process (GO:0006401)4.56612082
25formation of translation preinitiation complex (GO:0001731)4.53684588
26regulation of translational fidelity (GO:0006450)4.22198368
27DNA deamination (GO:0045006)4.14690772
28mitotic chromosome condensation (GO:0007076)4.10703652
29DNA strand elongation involved in DNA replication (GO:0006271)4.00304393
30DNA unwinding involved in DNA replication (GO:0006268)3.90635566
31nuclear pore complex assembly (GO:0051292)3.89768937
32telomere maintenance via semi-conservative replication (GO:0032201)3.80319691
33* rRNA processing (GO:0006364)3.80262586
34DNA strand elongation (GO:0022616)3.78102927
35* rRNA metabolic process (GO:0016072)3.67163453
36DNA replication initiation (GO:0006270)3.50440500
37nuclear pore organization (GO:0006999)3.41763909
38* cellular component biogenesis (GO:0044085)3.40987876
39heterochromatin organization (GO:0070828)3.38953799
40negative regulation of RNA splicing (GO:0033119)3.37070826
41ncRNA 3-end processing (GO:0043628)3.34486058
42protein localization to kinetochore (GO:0034501)3.32588870
43nucleobase-containing small molecule interconversion (GO:0015949)3.31332393
44* establishment of protein localization to membrane (GO:0090150)3.30300984
45telomere maintenance via recombination (GO:0000722)3.28901482
46folic acid-containing compound biosynthetic process (GO:0009396)3.24262144
47spliceosomal snRNP assembly (GO:0000387)3.17782718
48establishment of integrated proviral latency (GO:0075713)3.16556725
49mitotic recombination (GO:0006312)3.14718286
50mitotic sister chromatid segregation (GO:0000070)3.14047883
51ribosome biogenesis (GO:0042254)3.10273832
52* establishment of protein localization to organelle (GO:0072594)3.08592679
53DNA topological change (GO:0006265)3.07968818
54spliceosomal complex assembly (GO:0000245)3.06951379
55mitochondrial ATP synthesis coupled proton transport (GO:0042776)3.05896812
56* protein targeting (GO:0006605)3.01680351
57ribosome assembly (GO:0042255)3.00392039
58telomere maintenance via telomere lengthening (GO:0010833)2.98682300
59DNA replication checkpoint (GO:0000076)2.98052545
60nucleobase biosynthetic process (GO:0046112)2.96667864
61nucleotide-excision repair, DNA gap filling (GO:0006297)2.95243699
62protein localization to chromosome, centromeric region (GO:0071459)2.94398938
63sister chromatid segregation (GO:0000819)2.92720254
64chromatin remodeling at centromere (GO:0031055)2.91718115
65CENP-A containing nucleosome assembly (GO:0034080)2.89319229
66DNA replication-dependent nucleosome assembly (GO:0006335)2.87523201
67DNA replication-dependent nucleosome organization (GO:0034723)2.87523201
68pore complex assembly (GO:0046931)2.86040262
69mitotic nuclear envelope disassembly (GO:0007077)2.85899791
70energy coupled proton transport, down electrochemical gradient (GO:0015985)2.85153563
71ATP synthesis coupled proton transport (GO:0015986)2.85153563
72regulation of mitochondrial translation (GO:0070129)2.83457752
73proline biosynthetic process (GO:0006561)2.81033401
74IMP biosynthetic process (GO:0006188)2.78921756
75regulation of mammary gland epithelial cell proliferation (GO:0033599)2.77922827
76pseudouridine synthesis (GO:0001522)2.77189830
77negative regulation of mRNA splicing, via spliceosome (GO:0048025)2.75583181
78termination of RNA polymerase II transcription (GO:0006369)2.73811384
79mRNA splicing, via spliceosome (GO:0000398)2.72917665
80RNA splicing, via transesterification reactions with bulged adenosine as nucleophile (GO:0000377)2.72917665
81RNA splicing, via transesterification reactions (GO:0000375)2.72778389
82kinetochore organization (GO:0051383)2.72416566
83DNA replication-independent nucleosome organization (GO:0034724)2.71991872
84DNA replication-independent nucleosome assembly (GO:0006336)2.71991872
85spliceosomal tri-snRNP complex assembly (GO:0000244)2.69654209
86* protein localization to organelle (GO:0033365)2.68936254
87* gene expression (GO:0010467)2.68900645
88deoxyribonucleoside monophosphate metabolic process (GO:0009162)2.67648941
89regulation of transcription involved in G1/S transition of mitotic cell cycle (GO:0000083)2.67204949
90transcription-coupled nucleotide-excision repair (GO:0006283)2.64892867
91oxidative phosphorylation (GO:0006119)2.64320052
92* cellular component disassembly (GO:0022411)2.63497957
93negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436)2.61770593
94nuclear envelope disassembly (GO:0051081)2.60761094
95membrane disassembly (GO:0030397)2.60761094
96purine nucleobase biosynthetic process (GO:0009113)2.59867025
97mitotic metaphase plate congression (GO:0007080)2.59359981
98* ncRNA processing (GO:0034470)2.59012029
99chromosome condensation (GO:0030261)2.56600137
100DNA duplex unwinding (GO:0032508)2.55325069
101establishment of protein localization to mitochondrial membrane (GO:0090151)2.55048426
102exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay 2.54497280
103regulation of RNA export from nucleus (GO:0046831)2.54140952
104* ribonucleoprotein complex assembly (GO:0022618)2.52663621
105viral mRNA export from host cell nucleus (GO:0046784)2.51963760
106* ribonucleoprotein complex subunit organization (GO:0071826)2.51508014
107IMP metabolic process (GO:0046040)2.51316040
108chromatin assembly or disassembly (GO:0006333)2.50512698
109histone mRNA metabolic process (GO:0008334)2.49838600
110regulation of histone H3-K9 methylation (GO:0051570)2.49138418
111pyrimidine nucleoside triphosphate biosynthetic process (GO:0009148)2.48018628
112regulation of protein heterodimerization activity (GO:0043497)2.47476669
113transcription elongation from RNA polymerase III promoter (GO:0006385)2.47116573
114termination of RNA polymerase III transcription (GO:0006386)2.47116573
115negative regulation of DNA repair (GO:0045738)2.47018488
116chromatin assembly (GO:0031497)2.46527057
117anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process (GO:02.46375861
118kinetochore assembly (GO:0051382)2.46112632
119pyrimidine nucleoside triphosphate metabolic process (GO:0009147)2.45698287
120protein complex localization (GO:0031503)2.45481565
121DNA-templated transcription, termination (GO:0006353)2.45180844
122negative regulation of mRNA processing (GO:0050686)2.44630394
123UTP biosynthetic process (GO:0006228)2.44270244
124pyrimidine ribonucleoside triphosphate biosynthetic process (GO:0009209)2.44193287
125regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051439)2.44022865
126* ncRNA metabolic process (GO:0034660)2.43718258
127* protein localization to membrane (GO:0072657)2.43715076
128negative regulation of ligase activity (GO:0051352)2.43352527
129negative regulation of ubiquitin-protein transferase activity (GO:0051444)2.43352527
130peptidyl-arginine omega-N-methylation (GO:0035247)2.43216721
131positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051437)2.42903181
132DNA geometric change (GO:0032392)2.41527994
133DNA conformation change (GO:0071103)2.39449693
134histone H2B ubiquitination (GO:0033523)2.36152275

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1E2F7_22180533_ChIP-Seq_HELA_Human6.98160430
2* MYC_18555785_ChIP-Seq_MESCs_Mouse4.75334762
3EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse4.09806160
4SOX9_22984422_ChIP-ChIP_TESTIS_Rat3.49493681
5* MYC_19079543_ChIP-ChIP_MESCs_Mouse3.47509872
6FOXM1_23109430_ChIP-Seq_U2OS_Human3.21104106
7E2F4_17652178_ChIP-ChIP_JURKAT_Human3.08774166
8EST1_17652178_ChIP-ChIP_JURKAT_Human3.05085513
9GABP_17652178_ChIP-ChIP_JURKAT_Human2.87896933
10* MYC_18358816_ChIP-ChIP_MESCs_Mouse2.85981671
11ETS1_20019798_ChIP-Seq_JURKAT_Human2.84042927
12* MYC_19030024_ChIP-ChIP_MESCs_Mouse2.82329178
13FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human2.76291390
14KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human2.73835760
15* XRN2_22483619_ChIP-Seq_HELA_Human2.64187136
16CREB1_15753290_ChIP-ChIP_HEK293T_Human2.60044889
17HCFC1_20581084_ChIP-Seq_MESCs_Mouse2.43008176
18JARID1A_20064375_ChIP-Seq_MESCs_Mouse2.42281166
19* CHD1_19587682_ChIP-ChIP_MESCs_Mouse2.34569029
20NELFA_20434984_ChIP-Seq_ESCs_Mouse2.23171504
21VDR_23849224_ChIP-Seq_CD4+_Human2.17433209
22TTF2_22483619_ChIP-Seq_HELA_Human2.09800065
23DCP1A_22483619_ChIP-Seq_HELA_Human1.98722148
24ELF1_17652178_ChIP-ChIP_JURKAT_Human1.97514333
25* E2F1_18555785_ChIP-Seq_MESCs_Mouse1.96498824
26* TAL1_20887958_ChIP-Seq_HPC-7_Mouse1.95789246
27SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse1.89346375
28FOXP3_21729870_ChIP-Seq_TREG_Human1.89107250
29MYC_22102868_ChIP-Seq_BL_Human1.82954179
30MYBL2_22936984_ChIP-ChIP_MESCs_Mouse1.82480356
31ELK1_19687146_ChIP-ChIP_HELA_Human1.79676374
32EGR1_19374776_ChIP-ChIP_THP-1_Human1.70869839
33HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human1.70322600
34GABP_19822575_ChIP-Seq_HepG2_Human1.65827816
35FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse1.65337615
36TP63_17297297_ChIP-ChIP_HaCaT_Human1.65281717
37E2F1_21310950_ChIP-Seq_MCF-7_Human1.63953301
38NOTCH1_17114293_ChIP-ChIP_T-ALL_Human1.62293943
39AR_21909140_ChIP-Seq_LNCAP_Human1.60965099
40POU5F1_18555785_ChIP-Seq_MESCs_Mouse1.60183183
41NANOG_18555785_ChIP-Seq_MESCs_Mouse1.57367890
42ZFX_18555785_ChIP-Seq_MESCs_Mouse1.52311507
43MYCN_18555785_ChIP-Seq_MESCs_Mouse1.51793171
44CIITA_25753668_ChIP-Seq_RAJI_Human1.51716632
45CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human1.51285395
46THAP11_20581084_ChIP-Seq_MESCs_Mouse1.50860833
47VDR_21846776_ChIP-Seq_THP-1_Human1.48882165
48HOXB4_20404135_ChIP-ChIP_EML_Mouse1.46142031
49* ZFP42_18358816_ChIP-ChIP_MESCs_Mouse1.45482218
50CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat1.43744481
51MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse1.40970673
52ESR1_15608294_ChIP-ChIP_MCF-7_Human1.36043529
53YY1_21170310_ChIP-Seq_MESCs_Mouse1.35391564
54KLF4_19030024_ChIP-ChIP_MESCs_Mouse1.35362329
55FLI1_20887958_ChIP-Seq_HPC-7_Mouse1.33160720
56ERG_20887958_ChIP-Seq_HPC-7_Mouse1.33015306
57STAT3_1855785_ChIP-Seq_MESCs_Mouse1.32549231
58FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse1.31619742
59TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse1.31251757
60KDM5A_27292631_Chip-Seq_BREAST_Human1.29243427
61SFPI1_20887958_ChIP-Seq_HPC-7_Mouse1.26148920
62CCND1_20090754_ChIP-ChIP_RETINA_Mouse1.24451000
63CEBPB_24764292_ChIP-Seq_MC3T3_Mouse1.23195755
64PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse1.22883534
65CREB1_20920259_ChIP-Seq_GC1-SPG_Mouse1.22816587
66YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.22146345
67SMAD1_18555785_ChIP-Seq_MESCs_Mouse1.20896751
68* POU5F1_18358816_ChIP-ChIP_MESCs_Mouse1.20485473
69POU5F1_18700969_ChIP-ChIP_MESCs_Mouse1.20466500
70E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse1.18899400
71PPARG_19300518_ChIP-PET_3T3-L1_Mouse1.18887774
72ELK1_22589737_ChIP-Seq_MCF10A_Human1.17865560
73SPI1_22096565_ChIP-ChIP_GC-B_Mouse1.16255704
74ZFP281_18358816_ChIP-ChIP_MESCs_Mouse1.13752419
75ASXL1_24218140_ChIP-Seq_BMDM_Mouse1.12859124
76KLF4_18358816_ChIP-ChIP_MESCs_Mouse1.12034051
77TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat1.11862647
78DACH1_20351289_ChIP-Seq_MDA-MB-231_Human1.11507505
79SOX2_18555785_ChIP-Seq_MESCs_Mouse1.10769206
80KLF4_18555785_ChIP-Seq_MESCs_Mouse1.10031531
81CREM_20920259_ChIP-Seq_GC1-SPG_Mouse1.08082489
82* CNOT3_19339689_ChIP-ChIP_MESCs_Mouse1.07657745
83RBPJ_22232070_ChIP-Seq_NCS_Mouse1.07250414
84TP63_19390658_ChIP-ChIP_HaCaT_Human1.07145885
85KDM2B_26808549_Chip-Seq_SIL-ALL_Human1.05901338
86MYC_18940864_ChIP-ChIP_HL60_Human1.05880587
87SRF_21415370_ChIP-Seq_HL-1_Mouse1.05692640
88CUX1_19635798_ChIP-ChIP_MULTIPLE_HUMAN_CANCER_TYPES_Human1.04246831
89RACK7_27058665_Chip-Seq_MCF-7_Human1.03475332
90HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse1.02816788
91CHD1_26751641_Chip-Seq_LNCaP_Human1.02806300
92SPI1_23547873_ChIP-Seq_NB4_Human1.01503403
93TCF3_18692474_ChIP-Seq_MEFs_Mouse1.00615633
94SREBP1_19666523_ChIP-Seq_LIVER_Mouse1.00130558
95TET1_21451524_ChIP-Seq_MESCs_Mouse0.99938965
96HSF1_23293686_ChIP-Seq_STHDH_STRIATAL_Mouse0.99870761
97ELK3_25401928_ChIP-Seq_HUVEC_Human0.99378369
98TFEB_21752829_ChIP-Seq_HELA_Human0.99292684
99* OCT4_18692474_ChIP-Seq_MEFs_Mouse0.95457555
100LXR_22292898_ChIP-Seq_THP-1_Human0.95271185
101BCL3_23251550_ChIP-Seq_MUSCLE_Mouse0.94793737
102NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse0.94256885
103NOTCH1_21737748_ChIP-Seq_TLL_Human0.93049662
104KDM5B_21448134_ChIP-Seq_MESCs_Mouse0.92968315
105E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human0.92608981
106TCFAP2C_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse0.92332273
107* CTCF_18555785_ChIP-Seq_MESCs_Mouse0.91601319
108GFI1B_20887958_ChIP-Seq_HPC-7_Mouse0.90310311
109NCOR1_26117541_ChIP-Seq_K562_Human0.90084016
110* ASH2L_23239880_ChIP-Seq_MESCs_Mouse0.89444131
111SRY_22984422_ChIP-ChIP_TESTIS_Rat0.88083918
112KLF6_26769127_Chip-Seq_PDAC-Cell_line_Human0.87858315
113* SOX2_18692474_ChIP-Seq_MEFs_Mouse0.86772634
114ZNF263_19887448_ChIP-Seq_K562_Human0.86234690
115* PADI4_21655091_ChIP-ChIP_MCF-7_Human0.85964728
116PDX1_19855005_ChIP-ChIP_MIN6_Mouse0.84775120
117UTX_26944678_Chip-Seq_JUKART_Human0.80208043
118MAF_26560356_Chip-Seq_TH2_Human0.79398291
119KLF4_18264089_ChIP-ChIP_MESCs_Mouse0.76673727

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0003693_abnormal_embryo_hatching4.60734145
2MP0004957_abnormal_blastocyst_morpholog4.02040603
3MP0009379_abnormal_foot_pigmentation3.61606231
4MP0010094_abnormal_chromosome_stability3.39608439
5MP0003111_abnormal_nucleus_morphology3.20584757
6MP0003077_abnormal_cell_cycle3.18978729
7MP0008057_abnormal_DNA_replication2.58948485
8MP0010352_gastrointestinal_tract_polyps2.33709402
9MP0002396_abnormal_hematopoietic_system2.31110515
10MP0008932_abnormal_embryonic_tissue2.16099512
11MP0008007_abnormal_cellular_replicative2.10546897
12MP0008058_abnormal_DNA_repair2.06406733
13MP0004185_abnormal_adipocyte_glucose1.99493431
14MP0000490_abnormal_crypts_of1.96830392
15MP0001730_embryonic_growth_arrest1.84671014
16MP0000350_abnormal_cell_proliferation1.80681809
17MP0003786_premature_aging1.76299343
18MP0000566_synostosis1.73184522
19MP0002877_abnormal_melanocyte_morpholog1.67415941
20MP0003567_abnormal_fetal_cardiomyocyte1.67390033
21MP0004808_abnormal_hematopoietic_stem1.64640113
22MP0003123_paternal_imprinting1.63292649
23MP0002697_abnormal_eye_size1.55590445
24MP0003763_abnormal_thymus_physiology1.55291467
25MP0009333_abnormal_splenocyte_physiolog1.54822377
26MP0006292_abnormal_olfactory_placode1.50804697
27MP0010030_abnormal_orbit_morphology1.49760702
28MP0006054_spinal_hemorrhage1.47542655
29MP0002009_preneoplasia1.42796953
30MP0003941_abnormal_skin_development1.41417237
31MP0001346_abnormal_lacrimal_gland1.40942408
32MP0001697_abnormal_embryo_size1.37493880
33MP0002019_abnormal_tumor_incidence1.35708503
34MP0009672_abnormal_birth_weight1.35347675
35MP0002080_prenatal_lethality1.31970983
36MP0010307_abnormal_tumor_latency1.31174308
37MP0001672_abnormal_embryogenesis/_devel1.30586755
38MP0005380_embryogenesis_phenotype1.30586755
39MP0000537_abnormal_urethra_morphology1.27706294
40MP0004197_abnormal_fetal_growth/weight/1.27272913
41MP0000703_abnormal_thymus_morphology1.27251569
42MP0005408_hypopigmentation1.26536297
43MP0000313_abnormal_cell_death1.23660353
44MP0002249_abnormal_larynx_morphology1.22626365
45MP0002085_abnormal_embryonic_tissue1.22450277
46MP0003984_embryonic_growth_retardation1.19306061
47MP0001545_abnormal_hematopoietic_system1.18682402
48MP0005397_hematopoietic_system_phenotyp1.18682402
49MP0002086_abnormal_extraembryonic_tissu1.17938638
50MP0002088_abnormal_embryonic_growth/wei1.17920538
51MP0002163_abnormal_gland_morphology1.16975715
52MP0002398_abnormal_bone_marrow1.15584696
53MP0002722_abnormal_immune_system1.15075596
54MP0002084_abnormal_developmental_patter1.14852496
55MP0005451_abnormal_body_composition1.13657063
56MP0005023_abnormal_wound_healing1.12214719
57MP0000678_abnormal_parathyroid_gland1.11109428
58MP0005501_abnormal_skin_physiology1.09118887
59MP0005076_abnormal_cell_differentiation1.08860538
60MP0002938_white_spotting1.08589759
61MP0000750_abnormal_muscle_regeneration1.07531429
62MP0003315_abnormal_perineum_morphology1.07255894
63MP0001293_anophthalmia1.06856531
64MP0002166_altered_tumor_susceptibility1.01848902
65MP0000689_abnormal_spleen_morphology1.01763135
66MP0000858_altered_metastatic_potential0.99289537
67MP0003942_abnormal_urinary_system0.97395253
68MP0009053_abnormal_anal_canal0.96547475
69MP0004233_abnormal_muscle_weight0.95918067
70MP0003186_abnormal_redox_activity0.95412415
71MP0003705_abnormal_hypodermis_morpholog0.94722137
72MP0002796_impaired_skin_barrier0.94677360
73MP0005666_abnormal_adipose_tissue0.94238679
74MP0002429_abnormal_blood_cell0.92976650
75MP0000465_gastrointestinal_hemorrhage0.92214401
76MP0003937_abnormal_limbs/digits/tail_de0.91954720
77MP0002132_abnormal_respiratory_system0.90984372
78MP0004858_abnormal_nervous_system0.90559699
79MP0009278_abnormal_bone_marrow0.90402610
80MP0002095_abnormal_skin_pigmentation0.89775031
81MP0010234_abnormal_vibrissa_follicle0.89727159
82MP0000477_abnormal_intestine_morphology0.88670156
83MP0000428_abnormal_craniofacial_morphol0.88460458
84MP0001800_abnormal_humoral_immune0.87890727
85MP0001853_heart_inflammation0.87464704
86MP0004264_abnormal_extraembryonic_tissu0.87136729
87MP0001348_abnormal_lacrimal_gland0.86559987
88MP0001881_abnormal_mammary_gland0.85635025
89MP0005174_abnormal_tail_pigmentation0.85490896
90MP0003385_abnormal_body_wall0.85433325
91MP0008995_early_reproductive_senescence0.82681195
92MP0001727_abnormal_embryo_implantation0.82531134
93MP0000685_abnormal_immune_system0.82470750
94MP0000716_abnormal_immune_system0.82081560
95MP0003806_abnormal_nucleotide_metabolis0.80640432
96MP0003566_abnormal_cell_adhesion0.80574008
97MP0002160_abnormal_reproductive_system0.80429102
98MP0001873_stomach_inflammation0.80421330
99MP0003453_abnormal_keratinocyte_physiol0.80248291
100MP0002111_abnormal_tail_morphology0.79783351
101MP0002210_abnormal_sex_determination0.79517536
102MP0010155_abnormal_intestine_physiology0.79502822
103MP0002006_tumorigenesis0.79157696
104MP0002405_respiratory_system_inflammati0.77821163
105MP0003718_maternal_effect0.77382756
106MP0000627_abnormal_mammary_gland0.76711797
107MP0001216_abnormal_epidermal_layer0.75017519
108MP0001340_abnormal_eyelid_morphology0.74716071
109MP0003136_yellow_coat_color0.74538380
110MP0006035_abnormal_mitochondrial_morpho0.73387777
111MP0000358_abnormal_cell_content/0.72855860
112MP0009250_abnormal_appendicular_skeleto0.72482229
113MP0002060_abnormal_skin_morphology0.72207797
114MP0002420_abnormal_adaptive_immunity0.71699613
115MP0002452_abnormal_antigen_presenting0.70478591
116MP0002098_abnormal_vibrissa_morphology0.70081596
117MP0001819_abnormal_immune_cell0.69905601
118MP0001661_extended_life_span0.69867139
119MP0001849_ear_inflammation0.68730654
120MP0003119_abnormal_digestive_system0.68612628
121MP0000049_abnormal_middle_ear0.67895883
122MP0009931_abnormal_skin_appearance0.67711351
123MP0003938_abnormal_ear_development0.66379992
124MP0000377_abnormal_hair_follicle0.66132263
125MP0001286_abnormal_eye_development0.65100543
126MP0002092_abnormal_eye_morphology0.64855765
127MP0005075_abnormal_melanosome_morpholog0.64634414
128MP0003890_abnormal_embryonic-extraembry0.64315997
129MP0002233_abnormal_nose_morphology0.64127847
130MP0001145_abnormal_male_reproductive0.63874834
131MP0002282_abnormal_trachea_morphology0.63287704
132MP0001186_pigmentation_phenotype0.63243612
133MP0000733_abnormal_muscle_development0.62951425
134MP0004381_abnormal_hair_follicle0.62343420
135MP0001835_abnormal_antigen_presentation0.62026205
136MP0000762_abnormal_tongue_morphology0.61997465
137MP0004133_heterotaxia0.61384776

Predicted human phenotypes

RankGene SetZ-score
1* Abnormality of cells of the erythroid lineage (HP:0012130)7.90926066
2* Reticulocytopenia (HP:0001896)6.91329418
3* Abnormal number of erythroid precursors (HP:0012131)6.60192325
4* Macrocytic anemia (HP:0001972)5.77063150
5* Pallor (HP:0000980)5.31961407
6Colon cancer (HP:0003003)3.90437916
7Thrombocytosis (HP:0001894)3.57149822
8Chromosomal breakage induced by crosslinking agents (HP:0003221)3.38796420
9Microvesicular hepatic steatosis (HP:0001414)3.35117486
1011 pairs of ribs (HP:0000878)3.19982207
11Progressive muscle weakness (HP:0003323)3.16169643
12Oral leukoplakia (HP:0002745)3.12785485
13Multiple enchondromatosis (HP:0005701)3.12406080
14Absent thumb (HP:0009777)3.08428069
15Aplastic anemia (HP:0001915)3.08059832
16Aplasia/Hypoplasia of the sacrum (HP:0008517)3.03764597
17Trismus (HP:0000211)3.02591474
18Abnormal hemoglobin (HP:0011902)2.95160572
19Selective tooth agenesis (HP:0001592)2.93821617
20Birth length less than 3rd percentile (HP:0003561)2.92245169
21Breast hypoplasia (HP:0003187)2.70026897
22IgM deficiency (HP:0002850)2.52880457
23Broad distal phalanx of finger (HP:0009836)2.51314628
24Stenosis of the external auditory canal (HP:0000402)2.47698501
25Congenital, generalized hypertrichosis (HP:0004540)2.44943464
26Microretrognathia (HP:0000308)2.43973798
27* Depressed nasal ridge (HP:0000457)2.43842629
28Duplication of thumb phalanx (HP:0009942)2.40430484
29Missing ribs (HP:0000921)2.39229961
30Progressive external ophthalmoplegia (HP:0000590)2.38789648
31Rough bone trabeculation (HP:0100670)2.37617313
32Carpal bone hypoplasia (HP:0001498)2.37575483
33* Abnormality of reticulocytes (HP:0004312)2.37212489
34Abnormality of the parietal bone (HP:0002696)2.34507812
35Atresia of the external auditory canal (HP:0000413)2.29597410
36Decreased activity of mitochondrial respiratory chain (HP:0008972)2.26686544
37Abnormal activity of mitochondrial respiratory chain (HP:0011922)2.26686544
38Patellar aplasia (HP:0006443)2.22450468
39Overlapping toe (HP:0001845)2.21534875
40Asplenia (HP:0001746)2.19394959
41Septate vagina (HP:0001153)2.18936285
42Abnormality of cochlea (HP:0000375)2.17633279
43Neoplasm of the pancreas (HP:0002894)2.16766452
44Myelodysplasia (HP:0002863)2.16621585
45Hyperacusis (HP:0010780)2.15857189
46Basal cell carcinoma (HP:0002671)2.14093925
47Abnormal number of incisors (HP:0011064)2.13616079
48Hypoplasia of the radius (HP:0002984)2.13045592
49Facial cleft (HP:0002006)2.12557478
50Aplasia/Hypoplasia of the patella (HP:0006498)2.12292000
51Glossoptosis (HP:0000162)2.10903641
52Triphalangeal thumb (HP:0001199)2.10112992
53Woolly hair (HP:0002224)2.06688437
54Nasolacrimal duct obstruction (HP:0000579)2.06573045
55Increased hepatocellular lipid droplets (HP:0006565)2.04705665
56* Thick lower lip vermilion (HP:0000179)2.03897335
57Premature graying of hair (HP:0002216)2.03797875
58Deep palmar crease (HP:0006191)2.03217419
59Aplasia/Hypoplasia of the spleen (HP:0010451)2.02399175
60Increased intramyocellular lipid droplets (HP:0012240)2.01409513
61Ependymoma (HP:0002888)2.01342299
62Premature ovarian failure (HP:0008209)1.99393569
63Increased nuchal translucency (HP:0010880)1.99233053
64Rhabdomyosarcoma (HP:0002859)1.98847437
65Degeneration of anterior horn cells (HP:0002398)1.98652920
66Abnormality of the anterior horn cell (HP:0006802)1.98652920
67Ankyloglossia (HP:0010296)1.98240284
68Medulloblastoma (HP:0002885)1.96740031
69Asymmetry of the thorax (HP:0001555)1.94219699
70Cleft eyelid (HP:0000625)1.93796468
71Horseshoe kidney (HP:0000085)1.90784565
72Poikiloderma (HP:0001029)1.89256544
73Abnormality of the preputium (HP:0100587)1.89216134
74Ragged-red muscle fibers (HP:0003200)1.89058255
75Exertional dyspnea (HP:0002875)1.88127997
76Syringomyelia (HP:0003396)1.87235244
77Spinal cord lesions (HP:0100561)1.87235244
78Proximal placement of thumb (HP:0009623)1.87077857
79Premature skin wrinkling (HP:0100678)1.86665019
80Acute necrotizing encephalopathy (HP:0006965)1.85571723
81Squamous cell carcinoma (HP:0002860)1.85171998
82Abnormality of the distal phalanx of the thumb (HP:0009617)1.84830582
83* Migraine (HP:0002076)1.83714895
84Chromsome breakage (HP:0040012)1.81930502
85Cellular immunodeficiency (HP:0005374)1.81650584
86Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688)1.81583751
87Sparse eyelashes (HP:0000653)1.80104119
88Absent radius (HP:0003974)1.79931620
89Deep philtrum (HP:0002002)1.79367357
90Abnormality of the calcaneus (HP:0008364)1.79332347
91Mitochondrial inheritance (HP:0001427)1.79167650
92Lipid accumulation in hepatocytes (HP:0006561)1.78518974
93Abnormality of the lacrimal duct (HP:0011481)1.77918187
94Deviation of the thumb (HP:0009603)1.76835615
95Morphological abnormality of the inner ear (HP:0011390)1.76184425
96High anterior hairline (HP:0009890)1.75968372
97Meckel diverticulum (HP:0002245)1.75909986
98Colitis (HP:0002583)1.73320117
99Respiratory difficulties (HP:0002880)1.72854702
100Abnormality of the phalanges of the hallux (HP:0010057)1.72820889
101Petechiae (HP:0000967)1.72464377
102Partial duplication of the phalanx of hand (HP:0009999)1.71834674
103Lymphoma (HP:0002665)1.70069747
104Increased muscle lipid content (HP:0009058)1.68128193
105Tracheoesophageal fistula (HP:0002575)1.67803135
106Sparse lateral eyebrow (HP:0005338)1.67767950
107Insomnia (HP:0100785)1.67236366
108Achilles tendon contracture (HP:0001771)1.66847911
109Abnormality of the ileum (HP:0001549)1.66738444
110Abnormal mitochondria in muscle tissue (HP:0008316)1.66725435
111Abnormality of chromosome stability (HP:0003220)1.66623706
112Abnormality of small intestinal villus morphology (HP:0011472)1.66496163
113Villous atrophy (HP:0011473)1.66496163
114Testicular atrophy (HP:0000029)1.66229126
115Agnosia (HP:0010524)1.65640276
116Pseudobulbar signs (HP:0002200)1.64296585
117Partial duplication of thumb phalanx (HP:0009944)1.63174567
118Neoplasm of the colon (HP:0100273)1.62995932
119Overriding aorta (HP:0002623)1.62243374
120Renal duplication (HP:0000075)1.61931613
121Aplasia involving forearm bones (HP:0009822)1.61852112
122Absent forearm bone (HP:0003953)1.61852112
123Gout (HP:0001997)1.61677154
124Increased CSF lactate (HP:0002490)1.61669967
125Abnormal trabecular bone morphology (HP:0100671)1.61009760
126Cerebral edema (HP:0002181)1.60853277
127Hypoparathyroidism (HP:0000829)1.60812704
128Aplasia/Hypoplasia of the thymus (HP:0010515)1.60737006
129Seborrheic dermatitis (HP:0001051)1.60440245
130Short middle phalanx of the 5th finger (HP:0004220)1.59823977
131Calcaneovalgus deformity (HP:0001848)1.59565034
132Rectal prolapse (HP:0002035)1.59537302
133Amaurosis fugax (HP:0100576)1.59351574
134Angiofibromas (HP:0010615)1.59236398
135Adenoma sebaceum (HP:0009720)1.59236398
136Hepatocellular necrosis (HP:0001404)1.59141588
137Bicuspid aortic valve (HP:0001647)1.58776385
138Truncus arteriosus (HP:0001660)1.58414978
139Acute encephalopathy (HP:0006846)1.57760110
140Abnormality of T cell physiology (HP:0011840)1.56715759
141Delayed cranial suture closure (HP:0000270)1.56640747
142Abnormality of glycolysis (HP:0004366)1.55566425
143Abnormality of the nasolacrimal system (HP:0000614)1.55529748
144Pancytopenia (HP:0001876)1.55383956
145Abnormality of oral frenula (HP:0000190)1.55154962
146Secondary amenorrhea (HP:0000869)1.53471198
147Short thumb (HP:0009778)1.50918597
148Abnormal lung lobation (HP:0002101)1.50378653
149Abnormality of abdominal situs (HP:0011620)1.50298899
150Abdominal situs inversus (HP:0003363)1.50298899
151Aplasia/Hypoplasia involving the carpal bones (HP:0006502)1.50127194

Predicted kinase interactions (KEA)

RankGene SetZ-score
1NME24.69383956
2BUB13.35273885
3WEE13.29967308
4SMG13.06430589
5CDC72.82551286
6RPS6KB22.82545814
7EEF2K2.76134135
8VRK22.44715697
9LRRK22.36990149
10TLK12.30330745
11PRPF4B2.11656723
12SRPK12.10274371
13NEK22.04321315
14PASK2.00048655
15EIF2AK11.91552484
16ICK1.84773244
17IRAK31.83433876
18VRK11.83237528
19STK161.82416104
20DYRK31.78427936
21TGFBR11.74772314
22TESK21.72693633
23PIM21.72537174
24PBK1.72175873
25MAP3K101.68799213
26PKN21.67769590
27CDK71.66295086
28AURKB1.65004914
29RPS6KA41.62751053
30MAP4K11.54799264
31MKNK11.44348797
32TTK1.40855396
33SCYL21.39264343
34EIF2AK31.37247636
35TSSK61.35581015
36BRAF1.32781690
37ARAF1.31536847
38PAK41.30987754
39EPHA21.30769750
40PLK11.30493655
41BRSK21.30208967
42KDR1.29595182
43STK101.29068121
44CDK41.27193246
45ILK1.25464637
46MAP3K81.24356938
47ATR1.21153841
48ACVR1B1.17927345
49MAPKAPK31.15964912
50MST41.15640048
51SIK11.15572067
52AURKA1.09687960
53FLT31.09557483
54PIM11.07143344
55NEK11.04172304
56BTK1.01255685
57MAP3K30.99184891
58STK40.98780637
59TRIB30.98712488
60PLK40.97105101
61TAF10.93165636
62MAP2K30.93037006
63LATS20.88065935
64CHEK20.87407233
65CDK120.84363460
66CSNK2A20.83407252
67CDK60.82756438
68CHEK10.82083499
69PAK10.77225483
70GRK60.74726259
71MKNK20.74612083
72RPS6KA50.73668036
73PAK20.72965293
74MST1R0.72501945
75KSR20.69537903
76TEC0.67671949
77TESK10.67616535
78CSNK2A10.67604410
79NME10.67184091
80BRD40.66971956
81FGFR40.66085132
82MAP3K130.65979535
83IRAK20.65113727
84MAP3K90.62084469
85PLK30.61008821
86CDK80.59673843
87CDK20.58547896
88STK240.57137304
89ATM0.56589462
90ZAP700.56547073
91MAP3K110.55636933
92TYRO30.53813877
93MAP2K20.53793709
94RPS6KC10.52605889
95RPS6KL10.52605889
96ERN10.51882383
97ALK0.51117915
98BRSK10.50117165
99BCKDK0.49181640
100AKT20.48792097
101RPS6KA60.48657353
102PDGFRA0.48543619
103TYK20.47249687
104TAOK20.46240771
105PRKCI0.46196581
106BLK0.46105974
107MAPKAPK20.44193461
108RAF10.42391226
109DAPK30.42047365
110ZAK0.41818557
111CSF1R0.40306586
112CDK190.39219439
113IKBKB0.39198511
114CDK11A0.38876795
115CSNK1E0.38585338
116CAMK1D0.38218778
117MELK0.37583598
118TTN0.37069134
119NLK0.36375255
120RPS6KA10.35597506
121EPHB20.34753358
122EIF2AK20.34313294
123SYK0.33875648
124MTOR0.33441799
125CDK10.33176900
126DYRK1B0.32967600
127CDK90.32714040
128RPS6KB10.32097787
129CLK10.31322372
130CCNB10.31092563
131PTK60.30340679

Predicted pathways (KEGG)

RankGene SetZ-score
1* Ribosome_Homo sapiens_hsa030107.30871436
2DNA replication_Homo sapiens_hsa030304.31418199
3Mismatch repair_Homo sapiens_hsa034303.52968525
4Spliceosome_Homo sapiens_hsa030403.25199894
5RNA polymerase_Homo sapiens_hsa030202.99925975
6Proteasome_Homo sapiens_hsa030502.98973282
7Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030082.83703710
8Nucleotide excision repair_Homo sapiens_hsa034202.51430990
9RNA transport_Homo sapiens_hsa030132.49084553
10Base excision repair_Homo sapiens_hsa034102.46064746
11Homologous recombination_Homo sapiens_hsa034402.44283022
12Pyrimidine metabolism_Homo sapiens_hsa002402.31491651
13One carbon pool by folate_Homo sapiens_hsa006702.18431972
14Cell cycle_Homo sapiens_hsa041101.94501784
15Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009701.89604543
16Non-homologous end-joining_Homo sapiens_hsa034501.64409899
17RNA degradation_Homo sapiens_hsa030181.55154823
18Fanconi anemia pathway_Homo sapiens_hsa034601.53033110
19Parkinsons disease_Homo sapiens_hsa050121.49124358
20Systemic lupus erythematosus_Homo sapiens_hsa053221.42993685
21Oxidative phosphorylation_Homo sapiens_hsa001901.41095254
22Protein export_Homo sapiens_hsa030601.39451951
23p53 signaling pathway_Homo sapiens_hsa041151.35388126
24Basal transcription factors_Homo sapiens_hsa030221.35137360
25Citrate cycle (TCA cycle)_Homo sapiens_hsa000201.27034471
26mRNA surveillance pathway_Homo sapiens_hsa030151.26032655
27Huntingtons disease_Homo sapiens_hsa050161.24983515
28Cytosolic DNA-sensing pathway_Homo sapiens_hsa046231.11798426
29Cyanoamino acid metabolism_Homo sapiens_hsa004601.07076109
30Purine metabolism_Homo sapiens_hsa002301.04121912
31Antigen processing and presentation_Homo sapiens_hsa046121.01313050
32Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049320.99657358
33Epstein-Barr virus infection_Homo sapiens_hsa051690.99514978
34Sulfur relay system_Homo sapiens_hsa041220.96461308
35Non-small cell lung cancer_Homo sapiens_hsa052230.95095463
36Primary immunodeficiency_Homo sapiens_hsa053400.91876497
37Herpes simplex infection_Homo sapiens_hsa051680.87867503
38Viral carcinogenesis_Homo sapiens_hsa052030.84711784
39Alzheimers disease_Homo sapiens_hsa050100.84257847
40Pancreatic cancer_Homo sapiens_hsa052120.81559041
41Pentose phosphate pathway_Homo sapiens_hsa000300.77920561
42HTLV-I infection_Homo sapiens_hsa051660.74164291
43Folate biosynthesis_Homo sapiens_hsa007900.73928803
44Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.68874797
45Fructose and mannose metabolism_Homo sapiens_hsa000510.68564160
46Small cell lung cancer_Homo sapiens_hsa052220.67417419
47Thyroid cancer_Homo sapiens_hsa052160.66985990
48Pyruvate metabolism_Homo sapiens_hsa006200.66846381
49Glutathione metabolism_Homo sapiens_hsa004800.66302611
502-Oxocarboxylic acid metabolism_Homo sapiens_hsa012100.66082345
51Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.65370089
52Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006300.64354222
53Transcriptional misregulation in cancer_Homo sapiens_hsa052020.63288754
54Drug metabolism - other enzymes_Homo sapiens_hsa009830.61956304
55Legionellosis_Homo sapiens_hsa051340.54489744
56Endometrial cancer_Homo sapiens_hsa052130.53831398
57Basal cell carcinoma_Homo sapiens_hsa052170.52377932
58Renal cell carcinoma_Homo sapiens_hsa052110.52188559
59Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.50727140
60N-Glycan biosynthesis_Homo sapiens_hsa005100.50685024
61Biosynthesis of amino acids_Homo sapiens_hsa012300.50413152
62MicroRNAs in cancer_Homo sapiens_hsa052060.48033120
63VEGF signaling pathway_Homo sapiens_hsa043700.47747547
64Alcoholism_Homo sapiens_hsa050340.47620242
65Selenocompound metabolism_Homo sapiens_hsa004500.46737514
66Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.45921190
67Bladder cancer_Homo sapiens_hsa052190.45918928
68Cysteine and methionine metabolism_Homo sapiens_hsa002700.45771078
69Hematopoietic cell lineage_Homo sapiens_hsa046400.45631903
70Apoptosis_Homo sapiens_hsa042100.45531872
71mTOR signaling pathway_Homo sapiens_hsa041500.44104678
72Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.43387104
73Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.41958950
74ErbB signaling pathway_Homo sapiens_hsa040120.41673051
75Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.41293493
76Chronic myeloid leukemia_Homo sapiens_hsa052200.40598648
77TGF-beta signaling pathway_Homo sapiens_hsa043500.39437392
78Acute myeloid leukemia_Homo sapiens_hsa052210.38353365
79Notch signaling pathway_Homo sapiens_hsa043300.38192887
80Thyroid hormone signaling pathway_Homo sapiens_hsa049190.36290194
81Lysine degradation_Homo sapiens_hsa003100.35670942
82Prion diseases_Homo sapiens_hsa050200.35574471
83Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.35448417
84NF-kappa B signaling pathway_Homo sapiens_hsa040640.35298296
85Measles_Homo sapiens_hsa051620.33860519
86Melanoma_Homo sapiens_hsa052180.32832967
87Hepatitis B_Homo sapiens_hsa051610.32052649
88Carbon metabolism_Homo sapiens_hsa012000.31850392
89Shigellosis_Homo sapiens_hsa051310.31489703
90Glioma_Homo sapiens_hsa052140.31377064
91HIF-1 signaling pathway_Homo sapiens_hsa040660.30671430
92Pathways in cancer_Homo sapiens_hsa052000.30643614
93Wnt signaling pathway_Homo sapiens_hsa043100.30458852
94Butirosin and neomycin biosynthesis_Homo sapiens_hsa005240.29675309
95Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001300.28840817
96Oocyte meiosis_Homo sapiens_hsa041140.28766155
97Other glycan degradation_Homo sapiens_hsa005110.27895573
98Intestinal immune network for IgA production_Homo sapiens_hsa046720.27656469
99Hippo signaling pathway_Homo sapiens_hsa043900.26863735
100Vitamin B6 metabolism_Homo sapiens_hsa007500.26474670
101Longevity regulating pathway - mammal_Homo sapiens_hsa042110.26173529
102Viral myocarditis_Homo sapiens_hsa054160.26142242
103NOD-like receptor signaling pathway_Homo sapiens_hsa046210.25930938
104Colorectal cancer_Homo sapiens_hsa052100.24147714
105B cell receptor signaling pathway_Homo sapiens_hsa046620.23642254
106Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.23583157
107Insulin signaling pathway_Homo sapiens_hsa049100.23386999
108Leukocyte transendothelial migration_Homo sapiens_hsa046700.23386200
109Metabolic pathways_Homo sapiens_hsa011000.22941031
110Fc epsilon RI signaling pathway_Homo sapiens_hsa046640.22621914
111Arginine biosynthesis_Homo sapiens_hsa002200.22090022
112Arachidonic acid metabolism_Homo sapiens_hsa005900.20219798
113Cardiac muscle contraction_Homo sapiens_hsa042600.20187257
114Hedgehog signaling pathway_Homo sapiens_hsa043400.19993278
115Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.19580410
116Jak-STAT signaling pathway_Homo sapiens_hsa046300.19292559
117Asthma_Homo sapiens_hsa053100.17408599
118Proteoglycans in cancer_Homo sapiens_hsa052050.17118286
119Renin-angiotensin system_Homo sapiens_hsa046140.16876447
120Central carbon metabolism in cancer_Homo sapiens_hsa052300.16157263
121Galactose metabolism_Homo sapiens_hsa000520.13907431
122Prostate cancer_Homo sapiens_hsa052150.13704759
123PI3K-Akt signaling pathway_Homo sapiens_hsa041510.13260847
124Cytokine-cytokine receptor interaction_Homo sapiens_hsa040600.12817731
125Influenza A_Homo sapiens_hsa051640.12188044
126AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049330.11478739

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