RPL9P2

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1ribosomal small subunit assembly (GO:0000028)5.04374748
2ATP synthesis coupled proton transport (GO:0015986)5.00001069
3energy coupled proton transport, down electrochemical gradient (GO:0015985)5.00001069
4viral transcription (GO:0019083)4.53742079
5mitochondrial ATP synthesis coupled proton transport (GO:0042776)4.35910132
6translational termination (GO:0006415)4.35509698
7protein neddylation (GO:0045116)4.33758163
8maturation of SSU-rRNA (GO:0030490)4.29584980
9behavioral response to nicotine (GO:0035095)4.17062696
10mitochondrial electron transport, NADH to ubiquinone (GO:0006120)4.14911549
11aggressive behavior (GO:0002118)4.03384990
12DNA deamination (GO:0045006)4.03113431
13SRP-dependent cotranslational protein targeting to membrane (GO:0006614)3.91436440
14tachykinin receptor signaling pathway (GO:0007217)3.89361360
15RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394)3.88429618
16tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388)3.88429618
17cotranslational protein targeting to membrane (GO:0006613)3.85291133
18protein targeting to ER (GO:0045047)3.81798922
19positive regulation of action potential (GO:0045760)3.81234142
20chaperone-mediated protein transport (GO:0072321)3.79474242
21electron transport chain (GO:0022900)3.78740395
22preassembly of GPI anchor in ER membrane (GO:0016254)3.77968795
23respiratory electron transport chain (GO:0022904)3.76431184
24epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287)3.72478922
25translational elongation (GO:0006414)3.72475884
26establishment of protein localization to endoplasmic reticulum (GO:0072599)3.66958276
27protein localization to endoplasmic reticulum (GO:0070972)3.63724782
28water-soluble vitamin biosynthetic process (GO:0042364)3.54191623
29GTP biosynthetic process (GO:0006183)3.50118033
30protein complex biogenesis (GO:0070271)3.43847498
31mitochondrial respiratory chain complex I assembly (GO:0032981)3.41783157
32NADH dehydrogenase complex assembly (GO:0010257)3.41783157
33mitochondrial respiratory chain complex I biogenesis (GO:0097031)3.41783157
34positive regulation of uterine smooth muscle contraction (GO:0070474)3.31254016
35mannosylation (GO:0097502)3.31083499
36regulation of action potential (GO:0098900)3.29781480
37negative regulation of telomere maintenance (GO:0032205)3.27067882
38nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291)3.22322983
39drinking behavior (GO:0042756)3.19769295
40viral life cycle (GO:0019058)3.18855943
41cellular protein complex disassembly (GO:0043624)3.13210591
42exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay 3.13158870
43ribosomal small subunit biogenesis (GO:0042274)3.11893949
44establishment of protein localization to mitochondrial membrane (GO:0090151)3.09184628
45maturation of 5.8S rRNA (GO:0000460)3.08072455
46fucose catabolic process (GO:0019317)3.05289286
47L-fucose metabolic process (GO:0042354)3.05289286
48L-fucose catabolic process (GO:0042355)3.05289286
49ribosomal large subunit biogenesis (GO:0042273)3.04778466
50mitochondrial respiratory chain complex assembly (GO:0033108)3.02717453
51RNA phosphodiester bond hydrolysis, exonucleolytic (GO:0090503)2.99947671
52purine nucleoside triphosphate biosynthetic process (GO:0009145)2.99182564
53kynurenine metabolic process (GO:0070189)2.98766252
54purine ribonucleoside triphosphate biosynthetic process (GO:0009206)2.98235953
55UTP metabolic process (GO:0046051)2.97662564
56positive regulation of tyrosine phosphorylation of Stat5 protein (GO:0042523)2.96960295
57regulation of cilium movement (GO:0003352)2.96626816
58nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184)2.94631581
59UTP biosynthetic process (GO:0006228)2.94156792
60positive regulation of inflammatory response to antigenic stimulus (GO:0002863)2.91239289
61translational initiation (GO:0006413)2.89155206
62rRNA catabolic process (GO:0016075)2.88922280
63proton transport (GO:0015992)2.87037679
64hydrogen transport (GO:0006818)2.83134374
65protein-cofactor linkage (GO:0018065)2.82531534
66ATP biosynthetic process (GO:0006754)2.81852139
67hydrogen ion transmembrane transport (GO:1902600)2.80248823
68regulation of tyrosine phosphorylation of Stat5 protein (GO:0042522)2.77671555
69protein polyglutamylation (GO:0018095)2.77548935
70resolution of meiotic recombination intermediates (GO:0000712)2.75305149
71positive regulation of prostaglandin secretion (GO:0032308)2.73446066
72translation (GO:0006412)2.72678941
73ubiquinone biosynthetic process (GO:0006744)2.71996372
74adaptation of signaling pathway (GO:0023058)2.70798403
75negative regulation of transcription elongation from RNA polymerase II promoter (GO:0034244)2.68357377
76base-excision repair, AP site formation (GO:0006285)2.68133038
77axoneme assembly (GO:0035082)2.67659621
78piRNA metabolic process (GO:0034587)2.66041508
79gonadal mesoderm development (GO:0007506)2.64426246
80positive regulation of digestive system process (GO:0060456)2.64180784
81ncRNA catabolic process (GO:0034661)2.63655115
82indolalkylamine catabolic process (GO:0046218)2.62540857
83tryptophan catabolic process (GO:0006569)2.62540857
84indole-containing compound catabolic process (GO:0042436)2.62540857
85amine catabolic process (GO:0009310)2.59677537
86cellular biogenic amine catabolic process (GO:0042402)2.59677537
87cellular ketone body metabolic process (GO:0046950)2.59220277
88C-terminal protein lipidation (GO:0006501)2.59118937
89GPI anchor metabolic process (GO:0006505)2.58599971
90epithelial cilium movement (GO:0003351)2.57300604
91pyrimidine deoxyribonucleotide catabolic process (GO:0009223)2.56522635
92cellular component biogenesis (GO:0044085)2.56397998
93tryptophan metabolic process (GO:0006568)2.56001872
94tRNA processing (GO:0008033)2.55868671
95regulation of microtubule-based movement (GO:0060632)2.55859914
96cellular response to ATP (GO:0071318)2.55009583
97positive regulation of mitochondrial fission (GO:0090141)2.54926161
98respiratory chain complex IV assembly (GO:0008535)2.54588392
99spliceosomal complex assembly (GO:0000245)2.54284855
100protein complex disassembly (GO:0043241)2.53411837

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1EZH2_22144423_ChIP-Seq_EOC_Human3.76559674
2ZNF274_21170338_ChIP-Seq_K562_Hela3.59279613
3GABP_17652178_ChIP-ChIP_JURKAT_Human3.54475590
4EST1_17652178_ChIP-ChIP_JURKAT_Human2.91268684
5HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human2.76417910
6KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human2.73412675
7VDR_22108803_ChIP-Seq_LS180_Human2.65941472
8ELF1_17652178_ChIP-ChIP_JURKAT_Human2.55174591
9GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse2.26933284
10MYCN_21190229_ChIP-Seq_SHEP-21N_Human2.23625162
11FLI1_27457419_Chip-Seq_LIVER_Mouse2.18206641
12JARID1A_20064375_ChIP-Seq_MESCs_Mouse2.03443560
13GBX2_23144817_ChIP-Seq_PC3_Human1.91205992
14VDR_23849224_ChIP-Seq_CD4+_Human1.90511707
15TP53_22573176_ChIP-Seq_HFKS_Human1.89133015
16NOTCH1_21737748_ChIP-Seq_TLL_Human1.87488044
17ETS1_20019798_ChIP-Seq_JURKAT_Human1.86002485
18EWS_26573619_Chip-Seq_HEK293_Human1.80007162
19CTBP1_25329375_ChIP-Seq_LNCAP_Human1.76740474
20ELK1_19687146_ChIP-ChIP_HELA_Human1.75784340
21SOX9_22984422_ChIP-ChIP_TESTIS_Rat1.75203438
22EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human1.74476149
23FOXP3_21729870_ChIP-Seq_TREG_Human1.72378389
24ZFP57_27257070_Chip-Seq_ESCs_Mouse1.70944463
25TAF15_26573619_Chip-Seq_HEK293_Human1.70378551
26HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse1.68973735
27SRF_21415370_ChIP-Seq_HL-1_Mouse1.62920676
28PCGF2_27294783_Chip-Seq_ESCs_Mouse1.62634484
29GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse1.60272140
30MYC_18940864_ChIP-ChIP_HL60_Human1.58538583
31TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat1.58034424
32PCGF2_27294783_Chip-Seq_NPCs_Mouse1.56971484
33FUS_26573619_Chip-Seq_HEK293_Human1.56773564
34IGF1R_20145208_ChIP-Seq_DFB_Human1.53029739
35P300_19829295_ChIP-Seq_ESCs_Human1.50959982
36MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human1.39560394
37FOXA1_25329375_ChIP-Seq_VCAP_Human1.38978289
38FOXA1_27270436_Chip-Seq_PROSTATE_Human1.38978289
39ETV2_25802403_ChIP-Seq_MESCs_Mouse1.38239947
40RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.35359071
41GATA3_21878914_ChIP-Seq_MCF-7_Human1.35179234
42ER_23166858_ChIP-Seq_MCF-7_Human1.35035309
43SOX2_19829295_ChIP-Seq_ESCs_Human1.34069217
44NANOG_19829295_ChIP-Seq_ESCs_Human1.34069217
45CTBP2_25329375_ChIP-Seq_LNCAP_Human1.31891360
46REST_21632747_ChIP-Seq_MESCs_Mouse1.29623345
47CREB1_15753290_ChIP-ChIP_HEK293T_Human1.28673938
48AR_20517297_ChIP-Seq_VCAP_Human1.28171462
49IRF4_20064451_ChIP-Seq_CD4+T_Mouse1.27974561
50CBP_20019798_ChIP-Seq_JUKART_Human1.27974561
51GLI1_17442700_ChIP-ChIP_MESCs_Mouse1.26224614
52POU3F2_20337985_ChIP-ChIP_501MEL_Human1.21829077
53NANOG_20526341_ChIP-Seq_ESCs_Human1.21066804
54NCOR_22424771_ChIP-Seq_293T_Human1.20810112
55SUZ12_27294783_Chip-Seq_NPCs_Mouse1.20732801
56NFE2_27457419_Chip-Seq_LIVER_Mouse1.20591679
57CBX2_27304074_Chip-Seq_ESCs_Mouse1.20402704
58BMI1_23680149_ChIP-Seq_NPCS_Mouse1.20342110
59TDRD3_21172665_ChIP-Seq_MCF-7_Human1.19110613
60YY1_21170310_ChIP-Seq_MESCs_Mouse1.17772794
61KLF5_20875108_ChIP-Seq_MESCs_Mouse1.17364953
62CHD1_19587682_ChIP-ChIP_MESCs_Mouse1.16986920
63CEBPA_26348894_ChIP-Seq_LIVER_Mouse1.16492031
64TCF4_22108803_ChIP-Seq_LS180_Human1.16412425
65TAF2_19829295_ChIP-Seq_ESCs_Human1.15814208
66PDX1_19855005_ChIP-ChIP_MIN6_Mouse1.15489437
67STAT1_20625510_ChIP-Seq_HELA_Human1.14854998
68IRF8_22096565_ChIP-ChIP_GC-B_Human1.13854335
69FOXH1_21741376_ChIP-Seq_EPCs_Human1.11637720
70FOXA1_21572438_ChIP-Seq_LNCaP_Human1.10479837
71MYC_19829295_ChIP-Seq_ESCs_Human1.09129623
72RNF2_27304074_Chip-Seq_NSC_Mouse1.08465501
73FOXH1_21741376_ChIP-Seq_ESCs_Human1.08221560
74ETV1_20927104_ChIP-Seq_GIST48_Human1.07841593
75LYL1_20887958_ChIP-Seq_HPC-7_Mouse1.05847400
76BCAT_22108803_ChIP-Seq_LS180_Human1.05807872
77ERA_21632823_ChIP-Seq_H3396_Human1.04716634
78GATA6_21074721_ChIP-Seq_CACO-2_Human1.02819513
79AR_21572438_ChIP-Seq_LNCaP_Human1.02804462
80RBPJ_21746931_ChIP-Seq_IB4_Human1.02456515
81EZH2_27294783_Chip-Seq_NPCs_Mouse1.01625199
82EBNA2_21746931_ChIP-Seq_IB4-LCL_Human1.00961009
83MYC_18555785_ChIP-Seq_MESCs_Mouse1.00069971
84IRF1_19129219_ChIP-ChIP_H3396_Human0.99940849
85IKZF1_21737484_ChIP-ChIP_HCT116_Human0.99527080
86CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human0.99283795
87UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human0.98495513
88HOXB7_26014856_ChIP-Seq_BT474_Human0.98234823
89AUTS2_25519132_ChIP-Seq_293T-REX_Human0.98118495
90TTF2_22483619_ChIP-Seq_HELA_Human0.98107835
91GATA3_26560356_Chip-Seq_TH2_Human0.97392498
92OCT4_20526341_ChIP-Seq_ESCs_Human0.97178137
93PBX1_22567123_ChIP-ChIP_OVCAR3_Human0.95330958
94PAX6_23342162_ChIP-ChIP_BETA-FORBRAIN-LENS_Mouse0.95326391
95PHF8_20622853_ChIP-Seq_HELA_Human0.95286522
96TAL1_22897851_ChIP-Seq_JUKARTE6-1_Human0.94834736
97CEBPB_23403033_ChIP-Seq_LIVER_Mouse0.90213558
98RBPJ_21746931_ChIP-Seq_IB4-LCL_Human0.90207243
99GATA6_21074721_ChIP-Seq_CACO-2_Mouse0.89135226
100TOP2B_26459242_ChIP-Seq_MCF-7_Human0.88835037

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0008877_abnormal_DNA_methylation3.44393850
2MP0001968_abnormal_touch/_nociception3.34526565
3MP0002736_abnormal_nociception_after3.19210594
4MP0003787_abnormal_imprinting3.16380839
5MP0008872_abnormal_physiological_respon2.63376396
6MP0009379_abnormal_foot_pigmentation2.63357410
7MP0004142_abnormal_muscle_tone2.62896562
8MP0002837_dystrophic_cardiac_calcinosis2.61498959
9MP0003646_muscle_fatigue2.45705554
10MP0006292_abnormal_olfactory_placode2.38604130
11MP0008875_abnormal_xenobiotic_pharmacok2.27125921
12MP0001529_abnormal_vocalization2.17614695
13MP0004885_abnormal_endolymph2.04312689
14MP0002735_abnormal_chemical_nociception2.02547063
15MP0006072_abnormal_retinal_apoptosis1.93013093
16MP0002102_abnormal_ear_morphology1.86853453
17MP0003121_genomic_imprinting1.78860950
18MP0005551_abnormal_eye_electrophysiolog1.72528675
19MP0003011_delayed_dark_adaptation1.72130755
20MP0008995_early_reproductive_senescence1.71098646
21MP0005645_abnormal_hypothalamus_physiol1.68436303
22MP0002272_abnormal_nervous_system1.64344842
23MP0003122_maternal_imprinting1.63444115
24MP0002277_abnormal_respiratory_mucosa1.57437043
25MP0009764_decreased_sensitivity_to1.57304645
26MP0001986_abnormal_taste_sensitivity1.56472339
27MP0006276_abnormal_autonomic_nervous1.56395366
28MP0002138_abnormal_hepatobiliary_system1.52998721
29MP0005646_abnormal_pituitary_gland1.52798700
30MP0006036_abnormal_mitochondrial_physio1.51391980
31MP0009745_abnormal_behavioral_response1.42122719
32MP0005075_abnormal_melanosome_morpholog1.39742386
33MP0009046_muscle_twitch1.37401926
34MP0001835_abnormal_antigen_presentation1.36528264
35MP0002876_abnormal_thyroid_physiology1.35489454
36MP0005671_abnormal_response_to1.33932208
37MP0001970_abnormal_pain_threshold1.33164325
38MP0002163_abnormal_gland_morphology1.32623656
39MP0005253_abnormal_eye_physiology1.32437435
40MP0000372_irregular_coat_pigmentation1.31202589
41MP0005367_renal/urinary_system_phenotyp1.30264315
42MP0000516_abnormal_urinary_system1.30264315
43MP0004145_abnormal_muscle_electrophysio1.29207759
44MP0001905_abnormal_dopamine_level1.28175804
45MP0003786_premature_aging1.28016915
46MP0005389_reproductive_system_phenotype1.25443700
47MP0004147_increased_porphyrin_level1.24785668
48MP0002572_abnormal_emotion/affect_behav1.22831397
49MP0002938_white_spotting1.22323681
50MP0003806_abnormal_nucleotide_metabolis1.20314546
51MP0001501_abnormal_sleep_pattern1.20258434
52MP0003880_abnormal_central_pattern1.16914874
53MP0002734_abnormal_mechanical_nocicepti1.16299732
54MP0003195_calcinosis1.16050897
55MP0002653_abnormal_ependyma_morphology1.15901954
56MP0002160_abnormal_reproductive_system1.15403100
57MP0001984_abnormal_olfaction1.14405402
58MP0001919_abnormal_reproductive_system1.13528851
59MP0002557_abnormal_social/conspecific_i1.13024750
60MP0005379_endocrine/exocrine_gland_phen1.11907692
61MP0001440_abnormal_grooming_behavior1.11698355
62MP0003186_abnormal_redox_activity1.11255707
63MP0004043_abnormal_pH_regulation1.09030827
64MP0001800_abnormal_humoral_immune1.08598408
65MP0004742_abnormal_vestibular_system1.07353290
66MP0002733_abnormal_thermal_nociception1.07094131
67MP0005670_abnormal_white_adipose1.05329165
68MP0001486_abnormal_startle_reflex1.03746184
69MP0005410_abnormal_fertilization1.02693306
70MP0008058_abnormal_DNA_repair1.02309181
71MP0008775_abnormal_heart_ventricle1.02251082
72MP0002067_abnormal_sensory_capabilities1.00822097
73MP0003718_maternal_effect0.99671987
74MP0002148_abnormal_hypersensitivity_rea0.98912556
75MP0002095_abnormal_skin_pigmentation0.97348069
76MP0001873_stomach_inflammation0.96064294
77MP0003252_abnormal_bile_duct0.91851042
78MP0005174_abnormal_tail_pigmentation0.90001524
79MP0006035_abnormal_mitochondrial_morpho0.86442319
80MP0005195_abnormal_posterior_eye0.82108866
81MP0000230_abnormal_systemic_arterial0.82017778
82MP0008007_abnormal_cellular_replicative0.81336445
83MP0003315_abnormal_perineum_morphology0.80429217
84MP0005084_abnormal_gallbladder_morpholo0.79221559
85MP0005636_abnormal_mineral_homeostasis0.79006387
86MP0000685_abnormal_immune_system0.78813644
87MP0003635_abnormal_synaptic_transmissio0.77818941
88MP0000778_abnormal_nervous_system0.77465120
89MP0004924_abnormal_behavior0.75600634
90MP0005386_behavior/neurological_phenoty0.75600634
91MP0008789_abnormal_olfactory_epithelium0.75511095
92MP0002638_abnormal_pupillary_reflex0.74899085
93MP0002184_abnormal_innervation0.74557982
94MP0002063_abnormal_learning/memory/cond0.74364943
95MP0009333_abnormal_splenocyte_physiolog0.73971275
96MP0002234_abnormal_pharynx_morphology0.72737857
97MP0000427_abnormal_hair_cycle0.72365721
98MP0002229_neurodegeneration0.72098988
99MP0004133_heterotaxia0.71614276
100MP0001929_abnormal_gametogenesis0.70790008

Predicted human phenotypes

RankGene SetZ-score
1Acute necrotizing encephalopathy (HP:0006965)4.53901047
2Abnormal mitochondria in muscle tissue (HP:0008316)4.00189450
3Acute encephalopathy (HP:0006846)3.86981301
4Mitochondrial inheritance (HP:0001427)3.79853495
5Reticulocytopenia (HP:0001896)3.78116094
6Progressive macrocephaly (HP:0004481)3.76773783
73-Methylglutaconic aciduria (HP:0003535)3.69795186
8Increased CSF lactate (HP:0002490)3.42737602
9Hepatocellular necrosis (HP:0001404)3.13388564
10Congenital stationary night blindness (HP:0007642)3.12300312
11Absent thumb (HP:0009777)3.09211965
12Abnormality of midbrain morphology (HP:0002418)3.00667532
13Molar tooth sign on MRI (HP:0002419)3.00667532
14Pancreatic cysts (HP:0001737)2.98205690
15Abnormality of DNA repair (HP:0003254)2.96349740
16Type II lissencephaly (HP:0007260)2.89614068
17Abnormal rod and cone electroretinograms (HP:0008323)2.89046061
18Optic disc pallor (HP:0000543)2.88737355
19Pancreatic fibrosis (HP:0100732)2.86889983
20Hepatic necrosis (HP:0002605)2.86884599
21Absent rod-and cone-mediated responses on ERG (HP:0007688)2.86713284
22Abolished electroretinogram (ERG) (HP:0000550)2.74353293
23Abnormality of cells of the erythroid lineage (HP:0012130)2.69314552
24Congenital, generalized hypertrichosis (HP:0004540)2.69140956
25Cerebral edema (HP:0002181)2.68057810
26Aplasia/Hypoplasia of the spleen (HP:0010451)2.57226769
27Type I transferrin isoform profile (HP:0003642)2.54667171
28Abnormal activity of mitochondrial respiratory chain (HP:0011922)2.54397993
29Decreased activity of mitochondrial respiratory chain (HP:0008972)2.54397993
30Medial flaring of the eyebrow (HP:0010747)2.52952763
31Abnormality of the renal cortex (HP:0011035)2.52642634
32Asplenia (HP:0001746)2.46073655
33Hypoplasia of the pons (HP:0012110)2.45352188
34Nephronophthisis (HP:0000090)2.44894788
35Absent/shortened dynein arms (HP:0200106)2.42258088
36Dynein arm defect of respiratory motile cilia (HP:0012255)2.42258088
37Abnormality of the pons (HP:0007361)2.40736646
38Pendular nystagmus (HP:0012043)2.38875810
39Stomatitis (HP:0010280)2.36120480
40Abnormal drinking behavior (HP:0030082)2.34534230
41Polydipsia (HP:0001959)2.34534230
42Lactic acidosis (HP:0003128)2.34035828
43Elevated erythrocyte sedimentation rate (HP:0003565)2.28469186
44Abnormal number of erythroid precursors (HP:0012131)2.25753714
45Hypoproteinemia (HP:0003075)2.23991518
46Supernumerary spleens (HP:0009799)2.22668602
47Aplasia/Hypoplasia of the uvula (HP:0010293)2.20317672
48Decreased electroretinogram (ERG) amplitude (HP:0000654)2.19359398
49Increased serum lactate (HP:0002151)2.19211187
50Leukodystrophy (HP:0002415)2.18761279
51Increased hepatocellular lipid droplets (HP:0006565)2.18088509
52Abnormality of the renal collecting system (HP:0004742)2.16351454
53Abnormality of the renal medulla (HP:0100957)2.15963797
54Cerebellar dysplasia (HP:0007033)2.14107330
55Reduced antithrombin III activity (HP:0001976)2.12193532
56Abnormality of the prostate (HP:0008775)2.11425895
57Renal cortical cysts (HP:0000803)2.10063179
58Keratoconus (HP:0000563)2.07385272
59Increased corneal curvature (HP:0100692)2.07385272
60Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688)2.06530045
61Lipid accumulation in hepatocytes (HP:0006561)2.05355099
62Macrocytic anemia (HP:0001972)2.02241590
63Methylmalonic acidemia (HP:0002912)2.02157198
64Bile duct proliferation (HP:0001408)2.01970734
65Abnormal biliary tract physiology (HP:0012439)2.01970734
66Duplicated collecting system (HP:0000081)1.99286153
67Renal Fanconi syndrome (HP:0001994)1.98995540
68Polyuria (HP:0000103)1.96800688
69Sclerocornea (HP:0000647)1.96345266
70Ketosis (HP:0001946)1.95351407
71True hermaphroditism (HP:0010459)1.93444681
72Lethargy (HP:0001254)1.93428392
73Abnormality of the ileum (HP:0001549)1.91513461
74Abnormality of alanine metabolism (HP:0010916)1.90961175
75Hyperalaninemia (HP:0003348)1.90961175
76Abnormality of pyruvate family amino acid metabolism (HP:0010915)1.90961175
77Lissencephaly (HP:0001339)1.90401564
78Respiratory failure (HP:0002878)1.90290733
79Meckel diverticulum (HP:0002245)1.89211504
80Increased intramyocellular lipid droplets (HP:0012240)1.89160273
81IgG deficiency (HP:0004315)1.88608595
82Abnormal glycosylation (HP:0012345)1.88362003
83Abnormal isoelectric focusing of serum transferrin (HP:0003160)1.88362003
84Abnormal protein N-linked glycosylation (HP:0012347)1.88362003
85Abnormal protein glycosylation (HP:0012346)1.88362003
86Muscle abnormality related to mitochondrial dysfunction (HP:0003800)1.87559057
87Oligomenorrhea (HP:0000876)1.87324505
88Attenuation of retinal blood vessels (HP:0007843)1.87265080
89Abnormality of the labia minora (HP:0012880)1.85543735
90Hypomagnesemia (HP:0002917)1.84261487
91Cystic liver disease (HP:0006706)1.83856029
92Pallor (HP:0000980)1.83442409
93Decreased central vision (HP:0007663)1.82091527
94Exercise intolerance (HP:0003546)1.80170008
95Abnormal respiratory epithelium morphology (HP:0012253)1.77112522
96Abnormal respiratory motile cilium morphology (HP:0005938)1.77112522
97Adrenal hypoplasia (HP:0000835)1.76323494
98Abnormality of the preputium (HP:0100587)1.76259042
99Aplasia/Hypoplasia of the optic nerve (HP:0008058)1.75047466
100X-linked dominant inheritance (HP:0001423)1.73004068

Predicted kinase interactions (KEA)

RankGene SetZ-score
1WNK43.60626301
2NUAK13.26085403
3ADRBK22.84126478
4VRK22.67599575
5TLK12.62400112
6BCKDK2.57644884
7ZAK2.42588573
8TAOK32.41646084
9FRK2.40549241
10WNK32.30297766
11PINK12.21997539
12GRK12.19899609
13CDK192.15077181
14DYRK22.14523839
15TXK1.90028243
16STK161.83386007
17PLK41.83262632
18MAPK131.78232835
19VRK11.68425642
20MAP4K21.67220390
21CAMKK21.64027208
22PHKG11.62311163
23PHKG21.62311163
24OXSR11.60166415
25STK391.49098735
26MUSK1.21906857
27MARK11.18148184
28BCR1.17997689
29MAP4K11.15619279
30TIE11.14570893
31PRKCG1.10749677
32GRK61.08404827
33TEC1.04694742
34SYK1.04066186
35MST40.98619433
36ITK0.97361133
37CSNK1G20.95457438
38PLK20.94496600
39TNIK0.90762981
40IKBKB0.85815757
41MAP3K120.81812806
42INSRR0.81231139
43DAPK20.79273055
44PASK0.78327008
45MAP3K40.78024934
46MAP2K60.75956448
47BMPR1B0.75165711
48MAP2K70.73839338
49ADRBK10.73632822
50FES0.73503163
51CAMKK10.72001198
52IKBKE0.71179312
53PIK3CA0.70029145
54MAP3K110.69554576
55STK110.66824085
56KIT0.65599597
57NME10.65273617
58PRKCE0.65165198
59ATR0.64577736
60CSNK1G30.64401534
61CDK30.63415594
62TNK20.62989422
63LYN0.61473562
64PRKCQ0.58379412
65PRKACA0.57643882
66MAP2K20.57385111
67BTK0.56076744
68MKNK10.55999199
69MAPKAPK50.55595641
70PLK30.55323280
71GRK50.55128665
72EPHA40.52424064
73CSF1R0.51121113
74RPS6KA50.50712749
75PAK30.50174634
76OBSCN0.49671790
77CAMK10.49345003
78TRIM280.48296574
79PRKCD0.45664766
80DYRK1A0.43572135
81CSNK1A1L0.42800544
82CASK0.42658871
83LCK0.42019592
84EPHB20.41722336
85PRKCA0.41221297
86CAMK2A0.41057133
87CHEK20.40846406
88EIF2AK10.39865497
89ABL20.38061285
90MAP3K140.37971774
91FLT30.37803534
92CSNK2A20.37343514
93CDK80.37163144
94NTRK20.36883807
95CSNK1A10.36604600
96DAPK30.36489013
97PRKG10.36073212
98CSNK1G10.35604514
99MINK10.35383164
100ATM0.35179094

Predicted pathways (KEGG)

RankGene SetZ-score
1Ribosome_Homo sapiens_hsa030103.84653661
2Oxidative phosphorylation_Homo sapiens_hsa001903.74659081
3Asthma_Homo sapiens_hsa053103.28128688
4Parkinsons disease_Homo sapiens_hsa050123.12105625
5Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005632.74653849
6Intestinal immune network for IgA production_Homo sapiens_hsa046722.49253316
7Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001302.45262093
8Allograft rejection_Homo sapiens_hsa053302.32706320
9Proteasome_Homo sapiens_hsa030502.22380639
10Autoimmune thyroid disease_Homo sapiens_hsa053202.19829798
11Linoleic acid metabolism_Homo sapiens_hsa005912.13355097
12Alzheimers disease_Homo sapiens_hsa050102.12153475
13Type I diabetes mellitus_Homo sapiens_hsa049402.09368926
14Huntingtons disease_Homo sapiens_hsa050162.00934554
15Protein export_Homo sapiens_hsa030602.00654491
16RNA polymerase_Homo sapiens_hsa030201.99685133
17Cardiac muscle contraction_Homo sapiens_hsa042601.98464919
18Homologous recombination_Homo sapiens_hsa034401.98370050
19Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049321.93463545
20alpha-Linolenic acid metabolism_Homo sapiens_hsa005921.89019007
21Graft-versus-host disease_Homo sapiens_hsa053321.80300708
22RNA degradation_Homo sapiens_hsa030181.71283062
23Fanconi anemia pathway_Homo sapiens_hsa034601.68135790
24Synthesis and degradation of ketone bodies_Homo sapiens_hsa000721.66433999
25Nitrogen metabolism_Homo sapiens_hsa009101.65136484
26Phototransduction_Homo sapiens_hsa047441.42383736
27Basal transcription factors_Homo sapiens_hsa030221.29420808
28Ether lipid metabolism_Homo sapiens_hsa005651.26947903
29Nicotine addiction_Homo sapiens_hsa050331.26672548
30Neuroactive ligand-receptor interaction_Homo sapiens_hsa040801.23877850
31Tryptophan metabolism_Homo sapiens_hsa003801.21914019
32Olfactory transduction_Homo sapiens_hsa047401.20265541
33Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030081.18869140
34Nucleotide excision repair_Homo sapiens_hsa034201.17326434
35Butanoate metabolism_Homo sapiens_hsa006501.12392443
36Arachidonic acid metabolism_Homo sapiens_hsa005901.06388970
37Propanoate metabolism_Homo sapiens_hsa006401.02795453
38Fat digestion and absorption_Homo sapiens_hsa049750.99523203
39Inflammatory bowel disease (IBD)_Homo sapiens_hsa053210.96711166
40One carbon pool by folate_Homo sapiens_hsa006700.96627812
41Taste transduction_Homo sapiens_hsa047420.94241068
42Primary immunodeficiency_Homo sapiens_hsa053400.92793276
43Valine, leucine and isoleucine degradation_Homo sapiens_hsa002800.91238770
44Rheumatoid arthritis_Homo sapiens_hsa053230.88648953
45Peroxisome_Homo sapiens_hsa041460.88361116
46Pentose and glucuronate interconversions_Homo sapiens_hsa000400.88256408
47Cytosolic DNA-sensing pathway_Homo sapiens_hsa046230.87955925
48Pyrimidine metabolism_Homo sapiens_hsa002400.86887037
49Taurine and hypotaurine metabolism_Homo sapiens_hsa004300.83432825
50Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.82975580
51Ascorbate and aldarate metabolism_Homo sapiens_hsa000530.81390896
52Mismatch repair_Homo sapiens_hsa034300.79412119
53Purine metabolism_Homo sapiens_hsa002300.79197686
54Morphine addiction_Homo sapiens_hsa050320.78004015
55Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.77763606
56Drug metabolism - cytochrome P450_Homo sapiens_hsa009820.77304440
57Maturity onset diabetes of the young_Homo sapiens_hsa049500.77101747
58Chemical carcinogenesis_Homo sapiens_hsa052040.76355285
59Steroid hormone biosynthesis_Homo sapiens_hsa001400.73562275
60Caffeine metabolism_Homo sapiens_hsa002320.72591697
61Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006300.71264279
62Retinol metabolism_Homo sapiens_hsa008300.68085297
63Metabolic pathways_Homo sapiens_hsa011000.67666711
64Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.64484681
65Antigen processing and presentation_Homo sapiens_hsa046120.63466618
66Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.62004910
67Hematopoietic cell lineage_Homo sapiens_hsa046400.56050009
68Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.55843536
69NOD-like receptor signaling pathway_Homo sapiens_hsa046210.53815750
70Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.53741396
71RNA transport_Homo sapiens_hsa030130.53490472
72beta-Alanine metabolism_Homo sapiens_hsa004100.52445986
73Cytokine-cytokine receptor interaction_Homo sapiens_hsa040600.52174748
74Spliceosome_Homo sapiens_hsa030400.51975317
75Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.51755342
76Ovarian steroidogenesis_Homo sapiens_hsa049130.50623835
77Glycerolipid metabolism_Homo sapiens_hsa005610.50496578
78Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.48205781
79Regulation of autophagy_Homo sapiens_hsa041400.45596432
80Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.44464845
81Cysteine and methionine metabolism_Homo sapiens_hsa002700.44094633
82SNARE interactions in vesicular transport_Homo sapiens_hsa041300.43178397
83GABAergic synapse_Homo sapiens_hsa047270.42711986
84Cyanoamino acid metabolism_Homo sapiens_hsa004600.41577671
85Insulin secretion_Homo sapiens_hsa049110.39736678
86Collecting duct acid secretion_Homo sapiens_hsa049660.39123521
87Glutamatergic synapse_Homo sapiens_hsa047240.38530623
88Selenocompound metabolism_Homo sapiens_hsa004500.35517529
89Salivary secretion_Homo sapiens_hsa049700.35034721
90Fatty acid elongation_Homo sapiens_hsa000620.32668789
91Serotonergic synapse_Homo sapiens_hsa047260.32282548
92Sulfur metabolism_Homo sapiens_hsa009200.32081148
93Primary bile acid biosynthesis_Homo sapiens_hsa001200.31537016
94Systemic lupus erythematosus_Homo sapiens_hsa053220.31042627
95Retrograde endocannabinoid signaling_Homo sapiens_hsa047230.29079204
96Staphylococcus aureus infection_Homo sapiens_hsa051500.27535986
97Fatty acid degradation_Homo sapiens_hsa000710.26600611
98Viral myocarditis_Homo sapiens_hsa054160.26012049
99Non-homologous end-joining_Homo sapiens_hsa034500.24954823
100Vitamin digestion and absorption_Homo sapiens_hsa049770.24544141

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