RPL32P3

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1behavioral response to nicotine (GO:0035095)5.27953429
2epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287)4.63959833
3DNA deamination (GO:0045006)4.23292227
4epithelial cilium movement (GO:0003351)3.96281427
5cilium or flagellum-dependent cell motility (GO:0001539)3.80019350
6axoneme assembly (GO:0035082)3.67917527
7cilium movement (GO:0003341)3.63323041
8preassembly of GPI anchor in ER membrane (GO:0016254)3.61774117
9mitochondrial respiratory chain complex I biogenesis (GO:0097031)3.57247114
10mitochondrial respiratory chain complex I assembly (GO:0032981)3.57247114
11NADH dehydrogenase complex assembly (GO:0010257)3.57247114
12protein complex biogenesis (GO:0070271)3.40913589
13cellular response to ATP (GO:0071318)3.28899905
14indolalkylamine metabolic process (GO:0006586)3.21706981
15water-soluble vitamin biosynthetic process (GO:0042364)3.17966174
16cornea development in camera-type eye (GO:0061303)3.14068878
17mitochondrial respiratory chain complex assembly (GO:0033108)3.12378302
18L-fucose metabolic process (GO:0042354)3.11399332
19L-fucose catabolic process (GO:0042355)3.11399332
20fucose catabolic process (GO:0019317)3.11399332
21negative regulation of mast cell activation (GO:0033004)3.07470553
22sulfation (GO:0051923)3.03197297
23axonemal dynein complex assembly (GO:0070286)3.02926295
24interkinetic nuclear migration (GO:0022027)2.97166507
25positive regulation of oligodendrocyte differentiation (GO:0048714)2.95828399
26response to pheromone (GO:0019236)2.94270043
27detection of light stimulus involved in sensory perception (GO:0050962)2.93928923
28detection of light stimulus involved in visual perception (GO:0050908)2.93928923
29rRNA catabolic process (GO:0016075)2.84906605
30mannosylation (GO:0097502)2.84566012
31indole-containing compound catabolic process (GO:0042436)2.83374895
32indolalkylamine catabolic process (GO:0046218)2.83374895
33tryptophan catabolic process (GO:0006569)2.83374895
34cell proliferation in forebrain (GO:0021846)2.81752735
35piRNA metabolic process (GO:0034587)2.80153156
36gamma-aminobutyric acid transport (GO:0015812)2.78764673
37positive regulation of defense response to virus by host (GO:0002230)2.78268195
38neural tube formation (GO:0001841)2.76192686
39nephron epithelium morphogenesis (GO:0072088)2.72429875
40nephron tubule morphogenesis (GO:0072078)2.72429875
41regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:00450912.70146625
42respiratory chain complex IV assembly (GO:0008535)2.69457565
43GPI anchor metabolic process (GO:0006505)2.68282280
44positive regulation of fatty acid transport (GO:2000193)2.67689895
45DNA demethylation (GO:0080111)2.65466249
46forebrain morphogenesis (GO:0048853)2.63025651
47cellular response to exogenous dsRNA (GO:0071360)2.60591028
48positive regulation of granulocyte differentiation (GO:0030854)2.60492009
49cytochrome complex assembly (GO:0017004)2.59641918
50somite development (GO:0061053)2.59556564
51negative regulation of telomere maintenance (GO:0032205)2.58529626
52regulation of germinal center formation (GO:0002634)2.57486989
53regulation of action potential (GO:0098900)2.56081158
54negative regulation of translation involved in gene silencing by miRNA (GO:0035278)2.55956740
55negative regulation of translation, ncRNA-mediated (GO:0040033)2.55956740
56regulation of translation, ncRNA-mediated (GO:0045974)2.55956740
57regulation of hippo signaling (GO:0035330)2.54440912
58DNA methylation involved in gamete generation (GO:0043046)2.54203483
59tryptophan metabolic process (GO:0006568)2.54031584
60cilium organization (GO:0044782)2.49926619
61histone H3-K9 methylation (GO:0051567)2.48919822
62protein polyglutamylation (GO:0018095)2.47454443
63regulation of interleukin-12 biosynthetic process (GO:0045075)2.46994883
64reciprocal meiotic recombination (GO:0007131)2.46310831
65reciprocal DNA recombination (GO:0035825)2.46310831
66protein localization to cilium (GO:0061512)2.45947103
67kidney morphogenesis (GO:0060993)2.44549820
68adaptation of signaling pathway (GO:0023058)2.41874303
69purine ribonucleoside bisphosphate metabolic process (GO:0034035)2.41776672
703-phosphoadenosine 5-phosphosulfate metabolic process (GO:0050427)2.41776672
71regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis (GO:00033392.41013311
72positive regulation of icosanoid secretion (GO:0032305)2.39553990
73double-strand break repair via homologous recombination (GO:0000724)2.39476510
74negative regulation by host of viral transcription (GO:0043922)2.39026093
75RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394)2.38818834
76tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388)2.38818834
77embryonic epithelial tube formation (GO:0001838)2.38656679
78histone H3-K4 trimethylation (GO:0080182)2.38622604
79cilium morphogenesis (GO:0060271)2.38240434
80recombinational repair (GO:0000725)2.38079186
81protein-cofactor linkage (GO:0018065)2.36607809
82purinergic nucleotide receptor signaling pathway (GO:0035590)2.36299645
83interferon-gamma production (GO:0032609)2.36027195
84tolerance induction (GO:0002507)2.35497187
85regulation of memory T cell differentiation (GO:0043380)2.35434689
86cilium assembly (GO:0042384)2.35191029
87base-excision repair, AP site formation (GO:0006285)2.34740261
88regulation of collateral sprouting (GO:0048670)2.34090252
89neuronal action potential (GO:0019228)2.33730879
90spinal cord motor neuron differentiation (GO:0021522)2.32517049
91positive regulation of fatty acid oxidation (GO:0046321)2.32507516
92nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291)2.31335176
93photoreceptor cell development (GO:0042461)2.30758596
94regulation of cilium movement (GO:0003352)2.29226935
95motile cilium assembly (GO:0044458)2.29147879
96protein K11-linked deubiquitination (GO:0035871)2.28211172
97regulation of regulatory T cell differentiation (GO:0045589)2.27571664
98kynurenine metabolic process (GO:0070189)2.24791003
99cellular ketone body metabolic process (GO:0046950)2.24387350
100negative regulation of T cell differentiation in thymus (GO:0033085)2.24009386

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1ZNF274_21170338_ChIP-Seq_K562_Hela3.79945708
2EZH2_22144423_ChIP-Seq_EOC_Human2.90110979
3VDR_22108803_ChIP-Seq_LS180_Human2.80401999
4FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse2.79592635
5IRF8_22096565_ChIP-ChIP_GC-B_Human2.58046725
6HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse2.51617660
7RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse2.36505073
8HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human2.34080783
9NOTCH1_21737748_ChIP-Seq_TLL_Human2.16258054
10GBX2_23144817_ChIP-Seq_PC3_Human2.10857139
11MYCN_21190229_ChIP-Seq_SHEP-21N_Human2.08306105
12EWS_26573619_Chip-Seq_HEK293_Human2.07574150
13GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.99931784
14GABP_17652178_ChIP-ChIP_JURKAT_Human1.95878830
15FUS_26573619_Chip-Seq_HEK293_Human1.95174141
16EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human1.91045190
17ER_23166858_ChIP-Seq_MCF-7_Human1.87768879
18E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse1.81605060
19STAT6_20620947_ChIP-Seq_CD4_POS_T_Human1.81040260
20IGF1R_20145208_ChIP-Seq_DFB_Human1.80453480
21IRF1_19129219_ChIP-ChIP_H3396_Human1.75225168
22EST1_17652178_ChIP-ChIP_JURKAT_Human1.72981800
23GLI1_17442700_ChIP-ChIP_MESCs_Mouse1.69398189
24ZFP57_27257070_Chip-Seq_ESCs_Mouse1.68889169
25PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse1.66287248
26CTBP1_25329375_ChIP-Seq_LNCAP_Human1.64613620
27TP63_19390658_ChIP-ChIP_HaCaT_Human1.64134723
28POU3F2_20337985_ChIP-ChIP_501MEL_Human1.61501659
29MYC_18940864_ChIP-ChIP_HL60_Human1.58239522
30BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse1.58004646
31CTBP2_25329375_ChIP-Seq_LNCAP_Human1.57766015
32FLI1_27457419_Chip-Seq_LIVER_Mouse1.48818457
33VDR_23849224_ChIP-Seq_CD4+_Human1.47036596
34TP53_22573176_ChIP-Seq_HFKS_Human1.44852716
35BMI1_23680149_ChIP-Seq_NPCS_Mouse1.44072180
36MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human1.43203111
37BCAT_22108803_ChIP-Seq_LS180_Human1.39262821
38GATA3_21878914_ChIP-Seq_MCF-7_Human1.34328125
39P300_19829295_ChIP-Seq_ESCs_Human1.31292145
40TAF15_26573619_Chip-Seq_HEK293_Human1.30559113
41SCL_19346495_ChIP-Seq_HPC-7_Human1.30063672
42FOXA1_27270436_Chip-Seq_PROSTATE_Human1.25131606
43FOXA1_25329375_ChIP-Seq_VCAP_Human1.25131606
44GATA3_26560356_Chip-Seq_TH2_Human1.24173797
45RUNX_20019798_ChIP-Seq_JUKART_Human1.24024960
46NCOR_22424771_ChIP-Seq_293T_Human1.23827907
47IRF1_21803131_ChIP-Seq_MONOCYTES_Human1.22878500
48STAT3_23295773_ChIP-Seq_U87_Human1.21290590
49TDRD3_21172665_ChIP-Seq_MCF-7_Human1.21067311
50CBP_20019798_ChIP-Seq_JUKART_Human1.18609224
51IRF4_20064451_ChIP-Seq_CD4+T_Mouse1.18609224
52LYL1_20887958_ChIP-Seq_HPC-7_Mouse1.18467250
53EGR1_23403033_ChIP-Seq_LIVER_Mouse1.17957835
54SOX9_22984422_ChIP-ChIP_TESTIS_Rat1.16922717
55CBX2_27304074_Chip-Seq_ESCs_Mouse1.15946332
56* TCF4_23295773_ChIP-Seq_U87_Human1.15927137
57ERA_21632823_ChIP-Seq_H3396_Human1.15508396
58CEBPB_23403033_ChIP-Seq_LIVER_Mouse1.14937837
59UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human1.14573387
60POU5F1_26923725_Chip-Seq_MESODERM_Mouse1.13374406
61TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.13374406
62SALL1_21062744_ChIP-ChIP_HESCs_Human1.13242918
63CHD7_19251738_ChIP-ChIP_MESCs_Mouse1.13180192
64AR_20517297_ChIP-Seq_VCAP_Human1.10760458
65IRF8_21731497_ChIP-ChIP_J774_Mouse1.10492237
66CEBPD_23245923_ChIP-Seq_MEFs_Mouse1.10068255
67PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.09258197
68EBNA2_21746931_ChIP-Seq_IB4-LCL_Human1.08344223
69SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.08137993
70AR_21572438_ChIP-Seq_LNCaP_Human1.08040702
71HOXB7_26014856_ChIP-Seq_BT474_Human1.07955613
72ETV2_25802403_ChIP-Seq_MESCs_Mouse1.07574754
73FOXA1_21572438_ChIP-Seq_LNCaP_Human1.06966508
74AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human1.06684320
75PRDM14_20953172_ChIP-Seq_ESCs_Human1.06580169
76SMRT_27268052_Chip-Seq_Bcells_Human1.04911051
77VDR_20736230_ChIP-Seq_LYMPHOBLASTOID_Human1.04556092
78EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human1.04136224
79NR3C1_21868756_ChIP-Seq_MCF10A_Human1.03571600
80MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse1.01827739
81PCGF2_27294783_Chip-Seq_ESCs_Mouse1.01520637
82AUTS2_25519132_ChIP-Seq_293T-REX_Human1.01449672
83DROSHA_22980978_ChIP-Seq_HELA_Human1.01381958
84FOXP3_21729870_ChIP-Seq_TREG_Human1.01296417
85REST_21632747_ChIP-Seq_MESCs_Mouse1.00979159
86TAL1_22897851_ChIP-Seq_JUKARTE6-1_Human1.00721550
87CIITA_25753668_ChIP-Seq_RAJI_Human1.00704426
88GATA3_27048872_Chip-Seq_THYMUS_Human0.99477438
89* GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse0.99053319
90SOX2_19829295_ChIP-Seq_ESCs_Human0.97205834
91NANOG_19829295_ChIP-Seq_ESCs_Human0.97205834
92SRF_21415370_ChIP-Seq_HL-1_Mouse0.96985727
93RBPJ_21746931_ChIP-Seq_IB4-LCL_Human0.96687563
94CEBPA_23403033_ChIP-Seq_LIVER_Mouse0.94561322
95SUZ12_27294783_Chip-Seq_NPCs_Mouse0.93914169
96* FLI1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.93530680
97* CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human0.93333421
98NANOG_20526341_ChIP-Seq_ESCs_Human0.92348671
99STAT6_21828071_ChIP-Seq_BEAS2B_Human0.92314656
100IRF8_22096565_ChIP-ChIP_GC-B_Mouse0.92092801

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0006292_abnormal_olfactory_placode3.42086797
2MP0008877_abnormal_DNA_methylation2.98388435
3MP0005646_abnormal_pituitary_gland2.71611795
4MP0002653_abnormal_ependyma_morphology2.58325913
5MP0003195_calcinosis2.19073320
6MP0005174_abnormal_tail_pigmentation2.13191333
7MP0001986_abnormal_taste_sensitivity2.06361438
8MP0002138_abnormal_hepatobiliary_system2.05376441
9MP0003787_abnormal_imprinting1.98057679
10MP0008995_early_reproductive_senescence1.91747276
11MP0000685_abnormal_immune_system1.88115369
12MP0008875_abnormal_xenobiotic_pharmacok1.86811571
13MP0002876_abnormal_thyroid_physiology1.85730574
14MP0000569_abnormal_digit_pigmentation1.80017130
15MP0005551_abnormal_eye_electrophysiolog1.79591662
16MP0008872_abnormal_physiological_respon1.78769866
17MP0000372_irregular_coat_pigmentation1.78351204
18MP0002928_abnormal_bile_duct1.76364869
19MP0003136_yellow_coat_color1.75045655
20MP0004142_abnormal_muscle_tone1.74540811
21MP0002102_abnormal_ear_morphology1.73039017
22MP0003646_muscle_fatigue1.73027288
23MP0000631_abnormal_neuroendocrine_gland1.73025784
24MP0002277_abnormal_respiratory_mucosa1.72339456
25MP0002160_abnormal_reproductive_system1.65717987
26MP0005645_abnormal_hypothalamus_physiol1.65275179
27MP0005671_abnormal_response_to1.64956338
28MP0005084_abnormal_gallbladder_morpholo1.62107941
29MP0004043_abnormal_pH_regulation1.61448620
30MP0002638_abnormal_pupillary_reflex1.60651142
31MP0003724_increased_susceptibility_to1.53517173
32MP0001968_abnormal_touch/_nociception1.51483058
33MP0005389_reproductive_system_phenotype1.49776779
34MP0001835_abnormal_antigen_presentation1.45451176
35MP0001800_abnormal_humoral_immune1.45097516
36MP0002837_dystrophic_cardiac_calcinosis1.43644694
37MP0000383_abnormal_hair_follicle1.38887651
38MP0004133_heterotaxia1.37915898
39MP0003011_delayed_dark_adaptation1.37137655
40MP0001485_abnormal_pinna_reflex1.36265965
41MP0005075_abnormal_melanosome_morpholog1.34336147
42MP0006072_abnormal_retinal_apoptosis1.26022229
43MP0005253_abnormal_eye_physiology1.25803957
44MP0002163_abnormal_gland_morphology1.24577026
45MP0004130_abnormal_muscle_cell1.20877987
46MP0000015_abnormal_ear_pigmentation1.20005208
47MP0002938_white_spotting1.19534712
48MP0001790_abnormal_immune_system1.17482141
49MP0005387_immune_system_phenotype1.17482141
50MP0009379_abnormal_foot_pigmentation1.15773231
51MP0008058_abnormal_DNA_repair1.14065632
52MP0001873_stomach_inflammation1.13876465
53MP0004145_abnormal_muscle_electrophysio1.13357028
54MP0009046_muscle_twitch1.07358574
55MP0002132_abnormal_respiratory_system1.03574664
56MP0008789_abnormal_olfactory_epithelium1.03175817
57MP0002095_abnormal_skin_pigmentation1.01746496
58MP0005083_abnormal_biliary_tract0.97439618
59MP0002723_abnormal_immune_serum0.96604588
60MP0005379_endocrine/exocrine_gland_phen0.95735312
61MP0001764_abnormal_homeostasis0.94855505
62MP0001919_abnormal_reproductive_system0.94178259
63MP0009745_abnormal_behavioral_response0.92429314
64MP0003252_abnormal_bile_duct0.90455949
65MP0005310_abnormal_salivary_gland0.89885692
66MP0004885_abnormal_endolymph0.89805010
67MP0002452_abnormal_antigen_presenting0.88513807
68MP0000049_abnormal_middle_ear0.87954871
69MP0002420_abnormal_adaptive_immunity0.86903623
70MP0001819_abnormal_immune_cell0.84484802
71MP0004381_abnormal_hair_follicle0.83327740
72MP0002405_respiratory_system_inflammati0.82563603
73MP0002735_abnormal_chemical_nociception0.82459970
74MP0003786_premature_aging0.81992095
75MP0002272_abnormal_nervous_system0.81885280
76MP0002693_abnormal_pancreas_physiology0.81609688
77MP0005195_abnormal_posterior_eye0.81552981
78MP0001970_abnormal_pain_threshold0.79875927
79MP0000689_abnormal_spleen_morphology0.78836622
80MP0003938_abnormal_ear_development0.78497679
81MP0005220_abnormal_exocrine_pancreas0.77137333
82MP0004147_increased_porphyrin_level0.76428704
83MP0009764_decreased_sensitivity_to0.74761267
84MP0005000_abnormal_immune_tolerance0.74530889
85MP0002557_abnormal_social/conspecific_i0.71681960
86MP0006276_abnormal_autonomic_nervous0.71301825
87MP0000716_abnormal_immune_system0.71121015
88MP0009765_abnormal_xenobiotic_induced0.70333444
89MP0002398_abnormal_bone_marrow0.70053334
90MP0001486_abnormal_startle_reflex0.69899724
91MP0000427_abnormal_hair_cycle0.69469023
92MP0002733_abnormal_thermal_nociception0.69037530
93MP0000026_abnormal_inner_ear0.68977947
94MP0002736_abnormal_nociception_after0.67638982
95MP0005394_taste/olfaction_phenotype0.65571121
96MP0005499_abnormal_olfactory_system0.65571121
97MP0003698_abnormal_male_reproductive0.64937165
98MP0002148_abnormal_hypersensitivity_rea0.64554471
99MP0004742_abnormal_vestibular_system0.64170829
100MP0000230_abnormal_systemic_arterial0.64051707

Predicted human phenotypes

RankGene SetZ-score
1Pancreatic cysts (HP:0001737)4.52045164
2Pancreatic fibrosis (HP:0100732)3.94188493
3True hermaphroditism (HP:0010459)3.85772025
4Congenital stationary night blindness (HP:0007642)3.81257320
5Molar tooth sign on MRI (HP:0002419)3.61262124
6Abnormality of midbrain morphology (HP:0002418)3.61262124
7Absent/shortened dynein arms (HP:0200106)3.48041379
8Dynein arm defect of respiratory motile cilia (HP:0012255)3.48041379
9Nephronophthisis (HP:0000090)3.46148285
10Absent rod-and cone-mediated responses on ERG (HP:0007688)3.24487595
11Genetic anticipation (HP:0003743)3.21723547
12Abnormal respiratory epithelium morphology (HP:0012253)3.18339261
13Abnormal respiratory motile cilium morphology (HP:0005938)3.18339261
14Pendular nystagmus (HP:0012043)3.11728087
15Decreased central vision (HP:0007663)3.09201999
16Abnormality of the renal medulla (HP:0100957)3.04168424
17Cystic liver disease (HP:0006706)3.00819363
18Abnormal rod and cone electroretinograms (HP:0008323)3.00649754
19Attenuation of retinal blood vessels (HP:0007843)2.99402476
20Abnormal ciliary motility (HP:0012262)2.94812032
21Chronic hepatic failure (HP:0100626)2.92385921
22Abolished electroretinogram (ERG) (HP:0000550)2.90612693
23Abnormality of the renal cortex (HP:0011035)2.82037412
24Abnormal respiratory motile cilium physiology (HP:0012261)2.73400601
25Medial flaring of the eyebrow (HP:0010747)2.63352725
26Polydipsia (HP:0001959)2.55577113
27Abnormal drinking behavior (HP:0030082)2.55577113
28Progressive cerebellar ataxia (HP:0002073)2.54784216
29Type II lissencephaly (HP:0007260)2.53457081
30Gaze-evoked nystagmus (HP:0000640)2.46330826
31Respiratory insufficiency due to defective ciliary clearance (HP:0200073)2.43255046
32Keratoconus (HP:0000563)2.37525486
33Increased corneal curvature (HP:0100692)2.37525486
34Abnormality of DNA repair (HP:0003254)2.37002297
35Bony spicule pigmentary retinopathy (HP:0007737)2.36416476
36Aplasia/Hypoplasia of the spleen (HP:0010451)2.27659711
37Tubular atrophy (HP:0000092)2.27211756
38Abnormal biliary tract physiology (HP:0012439)2.26243612
39Bile duct proliferation (HP:0001408)2.26243612
40Asplenia (HP:0001746)2.21520919
41Absent thumb (HP:0009777)2.20457020
42Congenital hepatic fibrosis (HP:0002612)2.16841498
43Stomach cancer (HP:0012126)2.15699698
44Abnormal number of erythroid precursors (HP:0012131)2.14666373
45Abnormality of the nasal septum (HP:0000419)2.14314855
46Rhinitis (HP:0012384)2.13695869
47Sclerocornea (HP:0000647)2.12898332
48Decreased electroretinogram (ERG) amplitude (HP:0000654)2.11910045
49Stenosis of the external auditory canal (HP:0000402)2.08885116
503-Methylglutaconic aciduria (HP:0003535)2.08487365
51Male pseudohermaphroditism (HP:0000037)2.05533071
52Hyperventilation (HP:0002883)2.04249462
53Stomatitis (HP:0010280)2.02656026
54Acute necrotizing encephalopathy (HP:0006965)2.01551091
55Anencephaly (HP:0002323)2.01146503
56Renal cortical cysts (HP:0000803)1.96076342
57Panhypogammaglobulinemia (HP:0003139)1.95782115
58Mitochondrial inheritance (HP:0001427)1.93295400
59Severe combined immunodeficiency (HP:0004430)1.92852445
60Abnormality of the renal collecting system (HP:0004742)1.92238511
61Cerebellar dysplasia (HP:0007033)1.90731417
62Polyuria (HP:0000103)1.89778995
63Gait imbalance (HP:0002141)1.88900377
64Congenital primary aphakia (HP:0007707)1.88406230
65Methylmalonic aciduria (HP:0012120)1.88259143
66Abnormal delayed hypersensitivity skin test (HP:0002963)1.88029314
67Thyroiditis (HP:0100646)1.88018923
68Abnormality of cells of the erythroid lineage (HP:0012130)1.85814753
69Short 1st metacarpal (HP:0010034)1.85700546
70Aplasia/Hypoplasia of the 1st metacarpal (HP:0010026)1.85700546
71Methylmalonic acidemia (HP:0002912)1.84222911
72Aplasia/Hypoplasia of the tongue (HP:0010295)1.83447665
73Chronic sinusitis (HP:0011109)1.81929208
74Postaxial foot polydactyly (HP:0001830)1.81315506
75Furrowed tongue (HP:0000221)1.79096248
76Aplasia/Hypoplasia involving the musculature (HP:0001460)1.79002357
77Ectopic kidney (HP:0000086)1.78076631
78Hypoplasia of the pons (HP:0012110)1.77498359
79Tachypnea (HP:0002789)1.77488772
80Abnormality of the pons (HP:0007361)1.76058336
81Increased CSF lactate (HP:0002490)1.75489340
82Nephrogenic diabetes insipidus (HP:0009806)1.74654840
83Thyroid-stimulating hormone excess (HP:0002925)1.72825250
84Clumsiness (HP:0002312)1.72199420
85Chorioretinal atrophy (HP:0000533)1.70589481
86Bronchiectasis (HP:0002110)1.70309917
87Optic disc pallor (HP:0000543)1.69732365
88Carpal bone hypoplasia (HP:0001498)1.69653263
89Abnormal mitochondria in muscle tissue (HP:0008316)1.68811654
90IgG deficiency (HP:0004315)1.68417815
91Concave nail (HP:0001598)1.67611684
92Acute encephalopathy (HP:0006846)1.66620311
93Progressive macrocephaly (HP:0004481)1.66482379
94Abnormality of eosinophils (HP:0001879)1.65981579
95Occipital encephalocele (HP:0002085)1.63529375
96Decreased circulating renin level (HP:0003351)1.63405105
97Elevated erythrocyte sedimentation rate (HP:0003565)1.62126292
98Broad-based gait (HP:0002136)1.61907287
99Aplasia/Hypoplasia of the patella (HP:0006498)1.61511885
100Recurrent sinusitis (HP:0011108)1.59064530

Predicted kinase interactions (KEA)

RankGene SetZ-score
1FRK4.60865843
2TAOK33.22468315
3WNK42.82418112
4ADRBK22.77909166
5INSRR2.73468345
6GRK12.71167412
7MAPK152.43494521
8BMPR1B2.28067714
9TLK12.23401623
10MAP4K22.17217631
11TXK2.16997444
12ZAK2.02674926
13WNK32.01294359
14KIT1.87871867
15NUAK11.80213400
16MAP4K11.76269042
17TNK21.68862308
18MAPK131.60716974
19OXSR11.52188472
20MAP3K41.49094578
21PINK11.43685327
22FLT31.43662621
23ACVR1B1.42922265
24IKBKB1.42033936
25DAPK21.35708094
26TEC1.34554530
27STK391.33686123
28SIK21.25954906
29SYK1.20412918
30TNIK1.14728630
31MKNK21.06581691
32ADRBK11.02478975
33GRK61.01129817
34BLK0.97403199
35ITK0.96839283
36PTK2B0.93634077
37CAMKK20.92974304
38BTK0.92296104
39CSF1R0.90878580
40LYN0.88791586
41PRKCQ0.88309821
42RIPK40.85868191
43TIE10.85340321
44MAP3K70.84765030
45LCK0.78976144
46MAP2K60.77432163
47STK160.76430880
48STK110.76344282
49IKBKE0.76076653
50MAPKAPK30.75872219
51DYRK20.73840455
52MAP2K40.72397444
53MAP2K70.71291147
54JAK30.68393190
55PIK3CA0.66266614
56CHUK0.65806795
57RPS6KA60.64917224
58MUSK0.64235574
59BCKDK0.62201755
60ATR0.61516603
61PRKD20.59757463
62FES0.59755944
63PASK0.58787942
64NME10.57399636
65FGFR20.57173045
66RPS6KA50.54872725
67PRKCE0.53900748
68PAK30.53689598
69HCK0.52559332
70AKT30.52234320
71CSK0.51730144
72PRKCG0.49971061
73NLK0.49366542
74TGFBR10.49227825
75PRKAA10.48211976
76PNCK0.46940087
77PRKCH0.46880218
78BRSK20.46168360
79CSNK1A10.45179667
80SGK20.44724447
81MKNK10.43785791
82PIM10.43688588
83MATK0.42650312
84TRPM70.42509649
85MAPK110.42425900
86NEK20.41580453
87CAMK10.40646876
88PRKACA0.40342989
89VRK10.39617102
90VRK20.38674187
91SGK10.37492800
92DYRK30.37489934
93CSNK1D0.37308614
94WNK10.36868671
95MAPK30.34790654
96ABL10.34482270
97ERBB20.32207761
98RPS6KC10.31174889
99RPS6KL10.31174889
100NTRK30.29746823

Predicted pathways (KEGG)

RankGene SetZ-score
1Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005633.10122998
2Intestinal immune network for IgA production_Homo sapiens_hsa046722.46197562
3Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006032.32905194
4Maturity onset diabetes of the young_Homo sapiens_hsa049502.31168687
5Phototransduction_Homo sapiens_hsa047442.28982247
6Nitrogen metabolism_Homo sapiens_hsa009102.23934071
7Homologous recombination_Homo sapiens_hsa034402.11604376
8Primary immunodeficiency_Homo sapiens_hsa053402.11319719
9RNA polymerase_Homo sapiens_hsa030202.04524249
10Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001302.01591362
11Asthma_Homo sapiens_hsa053102.01291673
12Linoleic acid metabolism_Homo sapiens_hsa005911.92241843
13Allograft rejection_Homo sapiens_hsa053301.90089906
14Fanconi anemia pathway_Homo sapiens_hsa034601.87591874
15Neuroactive ligand-receptor interaction_Homo sapiens_hsa040801.85076327
16Oxidative phosphorylation_Homo sapiens_hsa001901.83325629
17alpha-Linolenic acid metabolism_Homo sapiens_hsa005921.74923787
18Autoimmune thyroid disease_Homo sapiens_hsa053201.73740548
19Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006041.70782470
20Graft-versus-host disease_Homo sapiens_hsa053321.70600538
21Type I diabetes mellitus_Homo sapiens_hsa049401.60930476
22Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006011.58598983
23Selenocompound metabolism_Homo sapiens_hsa004501.55734664
24Taurine and hypotaurine metabolism_Homo sapiens_hsa004301.54260716
25Ribosome_Homo sapiens_hsa030101.47466777
26Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005331.47352556
27Nicotine addiction_Homo sapiens_hsa050331.45840794
28Inflammatory bowel disease (IBD)_Homo sapiens_hsa053211.41461239
29Taste transduction_Homo sapiens_hsa047421.39728561
30Cytosolic DNA-sensing pathway_Homo sapiens_hsa046231.36651331
31Synthesis and degradation of ketone bodies_Homo sapiens_hsa000721.31980190
32RNA degradation_Homo sapiens_hsa030181.27897460
33Parkinsons disease_Homo sapiens_hsa050121.26956227
34Regulation of autophagy_Homo sapiens_hsa041401.26739181
35Ether lipid metabolism_Homo sapiens_hsa005651.26738657
36ABC transporters_Homo sapiens_hsa020101.22216948
37Chemical carcinogenesis_Homo sapiens_hsa052041.20357993
38Butanoate metabolism_Homo sapiens_hsa006501.15759176
39Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049321.15195605
40Huntingtons disease_Homo sapiens_hsa050161.13954769
41Basal transcription factors_Homo sapiens_hsa030221.10586106
42Drug metabolism - cytochrome P450_Homo sapiens_hsa009821.10567984
43Peroxisome_Homo sapiens_hsa041461.09347225
44Steroid hormone biosynthesis_Homo sapiens_hsa001401.04533920
45Olfactory transduction_Homo sapiens_hsa047401.02226789
46Morphine addiction_Homo sapiens_hsa050321.00281537
47Glycerolipid metabolism_Homo sapiens_hsa005610.99456594
48Tryptophan metabolism_Homo sapiens_hsa003800.98353844
49Hematopoietic cell lineage_Homo sapiens_hsa046400.97170013
50Ascorbate and aldarate metabolism_Homo sapiens_hsa000530.95377402
51SNARE interactions in vesicular transport_Homo sapiens_hsa041300.94161490
52Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.90457267
53Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.84579496
54Cytokine-cytokine receptor interaction_Homo sapiens_hsa040600.83934072
55RIG-I-like receptor signaling pathway_Homo sapiens_hsa046220.82464986
56Alzheimers disease_Homo sapiens_hsa050100.81329347
57Protein export_Homo sapiens_hsa030600.79845697
58Retinol metabolism_Homo sapiens_hsa008300.79598850
59Non-homologous end-joining_Homo sapiens_hsa034500.77788365
60Transcriptional misregulation in cancer_Homo sapiens_hsa052020.73662344
61NF-kappa B signaling pathway_Homo sapiens_hsa040640.72035817
62One carbon pool by folate_Homo sapiens_hsa006700.71814972
63Staphylococcus aureus infection_Homo sapiens_hsa051500.71807566
64Rheumatoid arthritis_Homo sapiens_hsa053230.71305737
65NOD-like receptor signaling pathway_Homo sapiens_hsa046210.68687308
66Arachidonic acid metabolism_Homo sapiens_hsa005900.66252518
67Pyrimidine metabolism_Homo sapiens_hsa002400.66008938
68Jak-STAT signaling pathway_Homo sapiens_hsa046300.64014948
69Histidine metabolism_Homo sapiens_hsa003400.63627205
70Valine, leucine and isoleucine degradation_Homo sapiens_hsa002800.62444353
71Antigen processing and presentation_Homo sapiens_hsa046120.61039099
72Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.60955849
73Purine metabolism_Homo sapiens_hsa002300.60735714
74Dorso-ventral axis formation_Homo sapiens_hsa043200.60408517
75Caffeine metabolism_Homo sapiens_hsa002320.59423170
76Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030080.59374061
77Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.58123606
78Nucleotide excision repair_Homo sapiens_hsa034200.56701458
79beta-Alanine metabolism_Homo sapiens_hsa004100.53862348
80Retrograde endocannabinoid signaling_Homo sapiens_hsa047230.53774369
81Base excision repair_Homo sapiens_hsa034100.52578508
82Collecting duct acid secretion_Homo sapiens_hsa049660.52504732
83Insulin secretion_Homo sapiens_hsa049110.52338678
84Ovarian steroidogenesis_Homo sapiens_hsa049130.51951607
85Calcium signaling pathway_Homo sapiens_hsa040200.50530378
86Serotonergic synapse_Homo sapiens_hsa047260.48981116
87Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.46523687
88Glycerophospholipid metabolism_Homo sapiens_hsa005640.45409771
89T cell receptor signaling pathway_Homo sapiens_hsa046600.42778327
90Circadian entrainment_Homo sapiens_hsa047130.41687601
91Systemic lupus erythematosus_Homo sapiens_hsa053220.41367995
92Cardiac muscle contraction_Homo sapiens_hsa042600.38920619
93Lysine degradation_Homo sapiens_hsa003100.38821850
94GABAergic synapse_Homo sapiens_hsa047270.38275292
95Herpes simplex infection_Homo sapiens_hsa051680.37854543
96Metabolic pathways_Homo sapiens_hsa011000.37666754
97Vitamin digestion and absorption_Homo sapiens_hsa049770.37655490
98Pentose and glucuronate interconversions_Homo sapiens_hsa000400.36786846
99Primary bile acid biosynthesis_Homo sapiens_hsa001200.36655179
100Glutamatergic synapse_Homo sapiens_hsa047240.34105941

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