RPL17P37

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1ribosomal small subunit biogenesis (GO:0042274)8.66873481
2viral transcription (GO:0019083)8.42227864
3translational termination (GO:0006415)8.04176109
4ribosomal small subunit assembly (GO:0000028)7.97680965
5maturation of SSU-rRNA (GO:0030490)7.66398214
6translational elongation (GO:0006414)6.57605870
7SRP-dependent cotranslational protein targeting to membrane (GO:0006614)6.54209419
8cotranslational protein targeting to membrane (GO:0006613)6.48310798
9protein targeting to ER (GO:0045047)6.44391381
10establishment of protein localization to endoplasmic reticulum (GO:0072599)6.17879875
11cellular protein complex disassembly (GO:0043624)6.17288998
12protein localization to endoplasmic reticulum (GO:0070972)6.06614404
13viral life cycle (GO:0019058)5.98479026
14nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184)5.87296747
15protein complex disassembly (GO:0043241)5.31351978
16epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287)5.16663119
17macromolecular complex disassembly (GO:0032984)4.99907317
18behavioral response to nicotine (GO:0035095)4.97806622
19translational initiation (GO:0006413)4.92801006
20ATP synthesis coupled proton transport (GO:0015986)4.62665790
21energy coupled proton transport, down electrochemical gradient (GO:0015985)4.62665790
22protein neddylation (GO:0045116)4.53505861
23protein targeting to membrane (GO:0006612)4.39817372
24substrate-independent telencephalic tangential interneuron migration (GO:0021843)4.38020205
25substrate-independent telencephalic tangential migration (GO:0021826)4.38020205
26pyrimidine nucleobase catabolic process (GO:0006208)4.29745776
27cell proliferation in forebrain (GO:0021846)4.13899176
28pattern specification involved in kidney development (GO:0061004)3.98850753
29chaperone-mediated protein transport (GO:0072321)3.95352943
30pyrimidine deoxyribonucleotide catabolic process (GO:0009223)3.94785131
31nuclear-transcribed mRNA catabolic process (GO:0000956)3.94066694
32ribosomal large subunit biogenesis (GO:0042273)3.87586683
33nonmotile primary cilium assembly (GO:0035058)3.75718525
34mitochondrial ATP synthesis coupled proton transport (GO:0042776)3.73929010
35mRNA catabolic process (GO:0006402)3.73054807
36epithelial cilium movement (GO:0003351)3.68815157
37translation (GO:0006412)3.59001110
38pyrimidine nucleotide catabolic process (GO:0006244)3.55934706
39head development (GO:0060322)3.54779450
40establishment of mitochondrion localization (GO:0051654)3.52630724
41mitochondrial respiratory chain complex I biogenesis (GO:0097031)3.50992543
42mitochondrial respiratory chain complex I assembly (GO:0032981)3.50992543
43NADH dehydrogenase complex assembly (GO:0010257)3.50992543
44body morphogenesis (GO:0010171)3.47029023
45nucleobase catabolic process (GO:0046113)3.43771007
46tongue development (GO:0043586)3.41817881
47neuron fate determination (GO:0048664)3.33086125
48RNA catabolic process (GO:0006401)3.28861762
49ribonucleoprotein complex biogenesis (GO:0022613)3.28211933
50protein complex biogenesis (GO:0070271)3.23907104
51axonal fasciculation (GO:0007413)3.22821328
52establishment of mitochondrion localization, microtubule-mediated (GO:0034643)3.21398879
53mitochondrion transport along microtubule (GO:0047497)3.21398879
54negative regulation of mast cell activation (GO:0033004)3.20307042
55regulation of cilium movement (GO:0003352)3.20295854
56regulation of microtubule-based movement (GO:0060632)3.17805477
57ncRNA 3-end processing (GO:0043628)3.17089123
58axonemal dynein complex assembly (GO:0070286)3.16828502
59cellular component biogenesis (GO:0044085)3.14677693
60respiratory electron transport chain (GO:0022904)3.14370780
61electron transport chain (GO:0022900)3.12876420
62response to redox state (GO:0051775)3.07872512
63hypothalamus development (GO:0021854)3.07097022
64mitochondrial electron transport, NADH to ubiquinone (GO:0006120)3.06671410
65GTP biosynthetic process (GO:0006183)3.05013543
66establishment of protein localization to membrane (GO:0090150)3.02622580
67cerebral cortex radially oriented cell migration (GO:0021799)3.01872344
68cilium movement (GO:0003341)3.00918004
69cardiovascular system development (GO:0072358)3.00320793
70segment specification (GO:0007379)3.00068494
71regulation of inhibitory postsynaptic membrane potential (GO:0060080)2.99801309
72synaptic transmission, cholinergic (GO:0007271)2.99402988
73spinal cord association neuron differentiation (GO:0021527)2.97519206
74short-term memory (GO:0007614)2.97032178
75positive regulation of respiratory burst (GO:0060267)2.96918924
76embryonic body morphogenesis (GO:0010172)2.95569969
77motile cilium assembly (GO:0044458)2.90730778
78somite development (GO:0061053)2.88001734
79negative regulation of transcription elongation from RNA polymerase II promoter (GO:0034244)2.87230955
80regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor act2.83272214
81mitochondrial respiratory chain complex assembly (GO:0033108)2.80801232
82protein polyglutamylation (GO:0018095)2.79637672
83intraciliary transport (GO:0042073)2.77969097
84protein targeting (GO:0006605)2.76810357
85ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway (GO:0043162.76538801
86neuron recognition (GO:0008038)2.76141222
87purine ribonucleoside triphosphate biosynthetic process (GO:0009206)2.71012531
88hydrogen ion transmembrane transport (GO:1902600)2.70742653
89auditory receptor cell differentiation (GO:0042491)2.68441716
90genetic imprinting (GO:0071514)2.63809447
91positive regulation of T cell apoptotic process (GO:0070234)2.61064762
92ATP biosynthetic process (GO:0006754)2.60275370
93purine nucleoside triphosphate biosynthetic process (GO:0009145)2.59914940
94establishment of protein localization to organelle (GO:0072594)2.55638188
95UTP biosynthetic process (GO:0006228)2.55032042
96central nervous system myelination (GO:0022010)2.54862195
97axon ensheathment in central nervous system (GO:0032291)2.54862195
98transmission of nerve impulse (GO:0019226)2.54858354
99establishment of protein localization to mitochondrial membrane (GO:0090151)2.50491413
100retinal ganglion cell axon guidance (GO:0031290)2.48781272

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1EZH2_22144423_ChIP-Seq_EOC_Human7.79051236
2TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat5.28878046
3NR4A2_19515692_ChIP-ChIP_MN9D_Mouse3.71931185
4EZH2_27304074_Chip-Seq_ESCs_Mouse2.44539348
5JARID2_20064375_ChIP-Seq_MESCs_Mouse2.37329883
6EZH2_27294783_Chip-Seq_ESCs_Mouse2.35314590
7RBPJ_22232070_ChIP-Seq_NCS_Mouse2.23754641
8SUZ12_27294783_Chip-Seq_ESCs_Mouse2.18303436
9CBX2_27304074_Chip-Seq_ESCs_Mouse2.16506856
10REST_21632747_ChIP-Seq_MESCs_Mouse1.98199896
11EED_16625203_ChIP-ChIP_MESCs_Mouse1.95604109
12RNF2_27304074_Chip-Seq_ESCs_Mouse1.93909509
13JARID2_20075857_ChIP-Seq_MESCs_Mouse1.91988045
14CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons1.91213510
15CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human1.84181276
16BMI1_23680149_ChIP-Seq_NPCS_Mouse1.80029377
17ERG_21242973_ChIP-ChIP_JURKAT_Human1.76518217
18EZH2_18974828_ChIP-Seq_MESCs_Mouse1.74114815
19RNF2_18974828_ChIP-Seq_MESCs_Mouse1.74114815
20RCOR2_21632747_ChIP-Seq_MESCs_Mouse1.73930188
21HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human1.67046150
22REST_18959480_ChIP-ChIP_MESCs_Mouse1.66412810
23GATA1_26923725_Chip-Seq_HPCs_Mouse1.64001766
24CTCF_27219007_Chip-Seq_Bcells_Human1.61816315
25SUZ12_18692474_ChIP-Seq_MESCs_Mouse1.59816157
26ZNF274_21170338_ChIP-Seq_K562_Hela1.58681115
27CEBPB_24764292_ChIP-Seq_MC3T3_Mouse1.56423217
28SUZ12_16625203_ChIP-ChIP_MESCs_Mouse1.54806614
29VDR_22108803_ChIP-Seq_LS180_Human1.53735272
30SIN3B_21632747_ChIP-Seq_MESCs_Mouse1.52493985
31PHC1_16625203_ChIP-ChIP_MESCs_Mouse1.50325127
32GABP_17652178_ChIP-ChIP_JURKAT_Human1.48385940
33SUZ12_20075857_ChIP-Seq_MESCs_Mouse1.46802164
34ETS1_20019798_ChIP-Seq_JURKAT_Human1.46115361
35SUZ12_18555785_ChIP-Seq_MESCs_Mouse1.45683064
36SUZ12_18692474_ChIP-Seq_MEFs_Mouse1.43590860
37HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse1.43418871
38SOX9_22984422_ChIP-ChIP_TESTIS_Rat1.42378014
39IRF1_19129219_ChIP-ChIP_H3396_Human1.41236942
40ETV2_25802403_ChIP-Seq_MESCs_Mouse1.40709715
41RNF2_27304074_Chip-Seq_NSC_Mouse1.37161449
42OLIG2_26023283_ChIP-Seq_AINV15_Mouse1.35111495
43ZFP322A_24550733_ChIP-Seq_MESCs_Mouse1.33164387
44IKZF1_21737484_ChIP-ChIP_HCT116_Human1.32486263
45GLI1_17442700_ChIP-ChIP_MESCs_Mouse1.31382940
46TP53_20018659_ChIP-ChIP_R1E_Mouse1.31086120
47KLF4_19030024_ChIP-ChIP_MESCs_Mouse1.29420710
48ERA_21632823_ChIP-Seq_H3396_Human1.27592366
49RCOR3_21632747_ChIP-Seq_MESCs_Mouse1.25706907
50RING1B_27294783_Chip-Seq_ESCs_Mouse1.25477050
51SUZ12_18974828_ChIP-Seq_MESCs_Mouse1.24828339
52SRY_22984422_ChIP-ChIP_TESTIS_Rat1.18755967
53TTF2_22483619_ChIP-Seq_HELA_Human1.18158355
54MTF2_20144788_ChIP-Seq_MESCs_Mouse1.16657783
55RNF2_16625203_ChIP-ChIP_MESCs_Mouse1.15890296
56TET1_21451524_ChIP-Seq_MESCs_Mouse1.14840181
57TAF2_19829295_ChIP-Seq_ESCs_Human1.14718245
58SIN3A_21632747_ChIP-Seq_MESCs_Mouse1.14528489
59EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human1.14207239
60GATA3_21878914_ChIP-Seq_MCF-7_Human1.10209543
61EBNA2_21746931_ChIP-Seq_IB4-LCL_Human1.09735662
62E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse1.08861793
63XRN2_22483619_ChIP-Seq_HELA_Human1.08789842
64OCT4_19829295_ChIP-Seq_ESCs_Human1.08327240
65YY1_22570637_ChIP-Seq_MALME-3M_Human1.05974516
66NANOG_20526341_ChIP-Seq_ESCs_Human1.05487288
67MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human1.04161229
68SMAD3_21741376_ChIP-Seq_ESCs_Human1.01890212
69MYC_18940864_ChIP-ChIP_HL60_Human1.01532097
70CEBPA_26348894_ChIP-Seq_LIVER_Mouse1.00964420
71P68_20966046_ChIP-Seq_HELA_Human1.00440446
72CTCF_20526341_ChIP-Seq_ESCs_Human0.99197016
73TP53_22573176_ChIP-Seq_HFKS_Human0.98523640
74P53_22127205_ChIP-Seq_FIBROBLAST_Human0.97989094
75BCL6_27268052_Chip-Seq_Bcells_Human0.97978952
76WDR5_24793694_ChIP-Seq_LNCAP_Human0.97310022
77MYCN_27167114_Chip-Seq_NEUROBLASTOMA_Human0.96898496
78RBPJ_21746931_ChIP-Seq_IB4-LCL_Human0.95602058
79FOXP1_21924763_ChIP-Seq_HESCs_Human0.95488491
80YY1_21170310_ChIP-Seq_MESCs_Mouse0.94252248
81JARID1A_20064375_ChIP-Seq_MESCs_Mouse0.93828381
82STAT6_21828071_ChIP-Seq_BEAS2B_Human0.93062679
83IGF1R_20145208_ChIP-Seq_DFB_Human0.92829090
84MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human0.91820573
85TP63_19390658_ChIP-ChIP_HaCaT_Human0.91720886
86E2F1_17053090_ChIP-ChIP_MCF-7_Human0.91173767
87EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse0.91120955
88TDRD3_21172665_ChIP-Seq_MCF-7_Human0.90420328
89DROSHA_22980978_ChIP-Seq_HELA_Human0.90061067
90CTBP1_25329375_ChIP-Seq_LNCAP_Human0.90054083
91CHD7_19251738_ChIP-ChIP_MESCs_Mouse0.89831468
92HCFC1_20581084_ChIP-Seq_MESCs_Mouse0.89311982
93SA1_27219007_Chip-Seq_Bcells_Human0.89243490
94GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse0.89066366
95CTCF_18555785_ChIP-Seq_MESCs_Mouse0.88113733
96TP53_22127205_ChIP-Seq_IMR90_Human0.87912824
97E2F1_20622854_ChIP-Seq_HELA_Human0.86317642
98SETDB1_19884257_ChIP-Seq_MESCs_Mouse0.85166266
99SOX2_18555785_ChIP-Seq_MESCs_Mouse0.84955743
100NCOR_22424771_ChIP-Seq_293T_Human0.84615846

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0009379_abnormal_foot_pigmentation5.93525533
2MP0006292_abnormal_olfactory_placode3.98434771
3MP0003122_maternal_imprinting3.82070444
4MP0003787_abnormal_imprinting3.61752993
5MP0003123_paternal_imprinting2.94117470
6MP0003121_genomic_imprinting2.77471747
7MP0002653_abnormal_ependyma_morphology2.72021852
8MP0008789_abnormal_olfactory_epithelium2.68584811
9MP0004142_abnormal_muscle_tone2.42989121
10MP0005394_taste/olfaction_phenotype2.41634799
11MP0005499_abnormal_olfactory_system2.41634799
12MP0008877_abnormal_DNA_methylation2.35604885
13MP0000778_abnormal_nervous_system2.19590904
14MP0003646_muscle_fatigue2.09449888
15MP0003136_yellow_coat_color2.09079009
16MP0005377_hearing/vestibular/ear_phenot2.07657055
17MP0003878_abnormal_ear_physiology2.07657055
18MP0001485_abnormal_pinna_reflex2.07002382
19MP0003879_abnormal_hair_cell1.90832664
20MP0000049_abnormal_middle_ear1.90052643
21MP0006276_abnormal_autonomic_nervous1.84003908
22MP0002163_abnormal_gland_morphology1.83270338
23MP0001293_anophthalmia1.72929786
24MP0004885_abnormal_endolymph1.70046867
25MP0000566_synostosis1.68773333
26MP0004742_abnormal_vestibular_system1.62269062
27MP0010030_abnormal_orbit_morphology1.51948073
28MP0001968_abnormal_touch/_nociception1.44987401
29MP0001529_abnormal_vocalization1.44483528
30MP0002063_abnormal_learning/memory/cond1.38163293
31MP0002557_abnormal_social/conspecific_i1.37437700
32MP0000955_abnormal_spinal_cord1.37028105
33MP0005551_abnormal_eye_electrophysiolog1.34644900
34MP0003635_abnormal_synaptic_transmissio1.34549527
35MP0001970_abnormal_pain_threshold1.34466493
36MP0002272_abnormal_nervous_system1.33844122
37MP0002733_abnormal_thermal_nociception1.29442700
38MP0009745_abnormal_behavioral_response1.28823350
39MP0002638_abnormal_pupillary_reflex1.27943862
40MP0002160_abnormal_reproductive_system1.22519405
41MP0003942_abnormal_urinary_system1.22513724
42MP0004133_heterotaxia1.22139582
43MP0000631_abnormal_neuroendocrine_gland1.20685495
44MP0004859_abnormal_synaptic_plasticity1.20236128
45MP0000026_abnormal_inner_ear1.20178414
46MP0002184_abnormal_innervation1.20068997
47MP0003880_abnormal_central_pattern1.19772018
48MP0005389_reproductive_system_phenotype1.18873658
49MP0005423_abnormal_somatic_nervous1.18861200
50MP0001984_abnormal_olfaction1.18335010
51MP0005195_abnormal_posterior_eye1.17587663
52MP0002735_abnormal_chemical_nociception1.16550294
53MP0002572_abnormal_emotion/affect_behav1.15626937
54MP0002734_abnormal_mechanical_nocicepti1.15596027
55MP0001440_abnormal_grooming_behavior1.15083179
56MP0001348_abnormal_lacrimal_gland1.13685797
57MP0002752_abnormal_somatic_nervous1.12570420
58MP0002938_white_spotting1.11851808
59MP0001986_abnormal_taste_sensitivity1.11563231
60MP0001919_abnormal_reproductive_system1.11355909
61MP0002095_abnormal_skin_pigmentation1.07086765
62MP0009046_muscle_twitch1.04518694
63MP0004145_abnormal_muscle_electrophysio1.03793473
64MP0002736_abnormal_nociception_after1.03451441
65MP0002067_abnormal_sensory_capabilities1.02067214
66MP0002882_abnormal_neuron_morphology1.01252901
67MP0001486_abnormal_startle_reflex1.01147808
68MP0001188_hyperpigmentation1.00721517
69MP0002233_abnormal_nose_morphology1.00268298
70MP0002064_seizures0.99891317
71MP0001905_abnormal_dopamine_level0.99669581
72MP0002152_abnormal_brain_morphology0.97935193
73MP0001963_abnormal_hearing_physiology0.96405279
74MP0005645_abnormal_hypothalamus_physiol0.95071725
75MP0005174_abnormal_tail_pigmentation0.94950655
76MP0002249_abnormal_larynx_morphology0.94390856
77MP0008872_abnormal_physiological_respon0.93483150
78MP0002876_abnormal_thyroid_physiology0.93170957
79MP0003755_abnormal_palate_morphology0.92440284
80MP0003937_abnormal_limbs/digits/tail_de0.92141094
81MP0004130_abnormal_muscle_cell0.91326251
82MP0003938_abnormal_ear_development0.90238910
83MP0005379_endocrine/exocrine_gland_phen0.87186942
84MP0003861_abnormal_nervous_system0.86449638
85MP0005084_abnormal_gallbladder_morpholo0.83481553
86MP0001502_abnormal_circadian_rhythm0.82639809
87MP0006072_abnormal_retinal_apoptosis0.81968471
88MP0009053_abnormal_anal_canal0.81441099
89MP0002837_dystrophic_cardiac_calcinosis0.80995167
90MP0001286_abnormal_eye_development0.80683586
91MP0001324_abnormal_eye_pigmentation0.79935737
92MP0008775_abnormal_heart_ventricle0.77702439
93MP0002102_abnormal_ear_morphology0.77463337
94MP0005391_vision/eye_phenotype0.77094312
95MP0003890_abnormal_embryonic-extraembry0.75757163
96MP0005646_abnormal_pituitary_gland0.74978525
97MP0002234_abnormal_pharynx_morphology0.74250561
98MP0002092_abnormal_eye_morphology0.72841673
99MP0004811_abnormal_neuron_physiology0.71618564
100MP0003186_abnormal_redox_activity0.70801647

Predicted human phenotypes

RankGene SetZ-score
1Reticulocytopenia (HP:0001896)7.22903837
2Abnormality of cells of the erythroid lineage (HP:0012130)4.70931027
3Abnormality of midbrain morphology (HP:0002418)4.09123876
4Molar tooth sign on MRI (HP:0002419)4.09123876
5Macrocytic anemia (HP:0001972)3.83537913
6Septo-optic dysplasia (HP:0100842)3.66324034
7Acute necrotizing encephalopathy (HP:0006965)3.62264120
8Pancreatic fibrosis (HP:0100732)3.50376430
9Pallor (HP:0000980)3.27530221
10Abnormal mitochondria in muscle tissue (HP:0008316)3.24788796
11Aplasia/Hypoplasia of the sacrum (HP:0008517)3.22019943
12Myokymia (HP:0002411)3.18148814
13Acute encephalopathy (HP:0006846)3.16564463
14Abnormal number of erythroid precursors (HP:0012131)2.96473606
15Absent thumb (HP:0009777)2.92449767
16Stenosis of the external auditory canal (HP:0000402)2.91655884
17Rib fusion (HP:0000902)2.90760079
18Polyphagia (HP:0002591)2.74115499
19Progressive macrocephaly (HP:0004481)2.73659928
20Medial flaring of the eyebrow (HP:0010747)2.71850396
21Agitation (HP:0000713)2.71113799
22Pancreatic cysts (HP:0001737)2.68550094
23Absent/shortened dynein arms (HP:0200106)2.62645521
24Dynein arm defect of respiratory motile cilia (HP:0012255)2.62645521
25Partial duplication of thumb phalanx (HP:0009944)2.62188068
26Abnormality of the diencephalon (HP:0010662)2.59978186
27Absent rod-and cone-mediated responses on ERG (HP:0007688)2.57892146
283-Methylglutaconic aciduria (HP:0003535)2.55661930
29Abnormality of the labia minora (HP:0012880)2.55042331
30Aplasia/Hypoplasia of the spleen (HP:0010451)2.54124082
31Abnormal respiratory epithelium morphology (HP:0012253)2.53441139
32Abnormal respiratory motile cilium morphology (HP:0005938)2.53441139
33Abnormal ciliary motility (HP:0012262)2.52356071
34Nephronophthisis (HP:0000090)2.50272834
35Gait imbalance (HP:0002141)2.50264955
36Mitochondrial inheritance (HP:0001427)2.48178794
37Asplenia (HP:0001746)2.47571559
38True hermaphroditism (HP:0010459)2.46026331
39Depressed nasal ridge (HP:0000457)2.45355997
40Sclerocornea (HP:0000647)2.42970325
41Pendular nystagmus (HP:0012043)2.42847314
42Abnormal hemoglobin (HP:0011902)2.40019398
43Pachygyria (HP:0001302)2.39509507
44Colon cancer (HP:0003003)2.35758526
45Congenital stationary night blindness (HP:0007642)2.33423156
46Anophthalmia (HP:0000528)2.32256244
47Hyperthyroidism (HP:0000836)2.31751396
48Supernumerary spleens (HP:0009799)2.29739823
49Anencephaly (HP:0002323)2.29522000
50Cystic liver disease (HP:0006706)2.25261807
51Hyperglycinemia (HP:0002154)2.24130660
52Type II lissencephaly (HP:0007260)2.23020766
53Abnormality of reticulocytes (HP:0004312)2.20984967
54Increased CSF lactate (HP:0002490)2.20778355
55Maternal diabetes (HP:0009800)2.18845313
56Partial duplication of the phalanx of hand (HP:0009999)2.17690828
57Abnormal rod and cone electroretinograms (HP:0008323)2.16543922
58Congenital primary aphakia (HP:0007707)2.16253148
59Elfin facies (HP:0004428)2.16251011
60Optic disc pallor (HP:0000543)2.14711754
61Abnormal respiratory motile cilium physiology (HP:0012261)2.14401071
62Renovascular hypertension (HP:0100817)2.12841932
63Chronic hepatic failure (HP:0100626)2.12186192
64Absent septum pellucidum (HP:0001331)2.11916976
6511 pairs of ribs (HP:0000878)2.11824428
66Tubular atrophy (HP:0000092)2.08675802
67Cerebral edema (HP:0002181)2.05781328
68Failure to thrive in infancy (HP:0001531)2.03946540
69Hypoplasia of the radius (HP:0002984)2.02877042
70Nephrogenic diabetes insipidus (HP:0009806)2.02395251
71Abnormal eating behavior (HP:0100738)2.01558790
72Papilledema (HP:0001085)2.01181791
73Optic nerve hypoplasia (HP:0000609)2.01144826
74Impulsivity (HP:0100710)2.00845129
75Lissencephaly (HP:0001339)2.00830087
76Postaxial foot polydactyly (HP:0001830)1.98641937
77Hip dysplasia (HP:0001385)1.97659545
78Abnormality of the renal medulla (HP:0100957)1.97426096
79Growth hormone deficiency (HP:0000824)1.95404436
80Ectopic kidney (HP:0000086)1.95029746
81Deep palmar crease (HP:0006191)1.92168264
82Abnormality of DNA repair (HP:0003254)1.91903919
83Narrow forehead (HP:0000341)1.91824443
84Overriding aorta (HP:0002623)1.90952616
85Oligodactyly (hands) (HP:0001180)1.90326975
86Bifid tongue (HP:0010297)1.90181349
87Renal duplication (HP:0000075)1.88927679
88Aplasia/Hypoplasia of the brainstem (HP:0007362)1.85355199
89Hypoplasia of the brainstem (HP:0002365)1.85355199
90Aplasia/Hypoplasia of the optic nerve (HP:0008058)1.84208398
91Vaginal atresia (HP:0000148)1.83369096
92Abnormal biliary tract physiology (HP:0012439)1.81131428
93Bile duct proliferation (HP:0001408)1.81131428
94Oligodactyly (HP:0012165)1.80654790
95Abnormality of the aortic arch (HP:0012303)1.79526444
96Hepatocellular necrosis (HP:0001404)1.78508749
97Respiratory insufficiency due to defective ciliary clearance (HP:0200073)1.78267146
98Polydipsia (HP:0001959)1.74889036
99Abnormal drinking behavior (HP:0030082)1.74889036
100Genital tract atresia (HP:0001827)1.74545461

Predicted kinase interactions (KEA)

RankGene SetZ-score
1WNK43.48286953
2STK163.28704900
3EPHB23.11780345
4DYRK22.90120897
5LIMK12.44319635
6WNK32.36839598
7MAP3K112.30101782
8LRRK22.20909142
9CASK2.20599702
10CDK192.11148088
11MARK12.07178314
12CAMKK21.99900525
13SIK21.94834311
14NTRK21.85390008
15PIK3CA1.84589391
16ADRBK21.80585796
17PINK11.70662302
18GRK11.69825927
19MAP2K71.66977569
20TYRO31.66848099
21CAMKK11.52343705
22EPHA41.40863281
23CAMK11.40852458
24PRKCG1.40281591
25DYRK1B1.38544054
26BCKDK1.37192756
27CAMK1D1.31474643
28STK391.29157751
29NEK21.27632433
30TIE11.27428235
31MINK11.26591046
32CDC71.21176580
33BRSK11.20172325
34CDC42BPA1.19792241
35NUAK11.15412748
36MAP4K21.14601897
37MAPK131.11729024
38PRKCH1.09669071
39WNK11.08819892
40STK111.08454389
41AURKA1.06252893
42MARK21.03769226
43MAP3K91.02245199
44BRAF1.00160974
45SGK4940.96011431
46SGK2230.96011431
47ABL20.95274928
48PAK30.93422090
49TLK10.93081155
50PDK20.90314001
51MAP3K40.88079083
52CAMK1G0.87583563
53PIM20.85606823
54PRKCZ0.85451146
55DAPK30.78394918
56FRK0.78002891
57CSNK1E0.76425422
58ADRBK10.74029428
59PHKG20.73691265
60PHKG10.73691265
61CDK80.71878747
62DMPK0.70926918
63TNIK0.70125009
64PRKACA0.69666403
65SGK10.68672102
66CSNK2A20.68633430
67CAMK40.64081634
68NTRK10.63806296
69PRKCQ0.62835921
70CDK140.62370097
71RPS6KA60.60743749
72PRKCI0.59937699
73NME10.59024665
74CDK50.56595075
75DYRK1A0.55323766
76PRKD30.53317956
77CDK11A0.53203192
78BMPR1B0.53086015
79TXK0.51632493
80PAK60.50743699
81RPS6KA20.49477261
82MAP2K40.48017467
83OXSR10.47846779
84INSRR0.46612076
85ICK0.46577830
86MAPK150.45628594
87RPS6KL10.45615773
88RPS6KC10.45615773
89NME20.45301994
90CSNK1G20.44698953
91CDK150.44617831
92PLK10.44244304
93AURKB0.43174877
94CAMK2A0.43020138
95AKT10.42722692
96DYRK30.41862548
97GRK70.41170932
98ARAF0.40922968
99PRKCA0.40814405
100RPS6KA30.40801318

Predicted pathways (KEGG)

RankGene SetZ-score
1Ribosome_Homo sapiens_hsa030107.10507673
2Oxidative phosphorylation_Homo sapiens_hsa001904.08401656
3Parkinsons disease_Homo sapiens_hsa050123.46527094
4Cardiac muscle contraction_Homo sapiens_hsa042603.37487673
5Sulfur relay system_Homo sapiens_hsa041222.70377216
6Huntingtons disease_Homo sapiens_hsa050162.65372963
7Alzheimers disease_Homo sapiens_hsa050102.62674128
8Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049322.43742655
9Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001302.29367335
10Synthesis and degradation of ketone bodies_Homo sapiens_hsa000722.08304595
11Linoleic acid metabolism_Homo sapiens_hsa005911.96137051
12alpha-Linolenic acid metabolism_Homo sapiens_hsa005921.90438209
13Nicotine addiction_Homo sapiens_hsa050331.88095960
14Terpenoid backbone biosynthesis_Homo sapiens_hsa009001.87535270
15Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005631.71454593
16Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005331.42766111
17Fat digestion and absorption_Homo sapiens_hsa049751.41313414
18Phototransduction_Homo sapiens_hsa047441.32287434
19RNA polymerase_Homo sapiens_hsa030201.29423581
20Basal cell carcinoma_Homo sapiens_hsa052171.28987466
21Butanoate metabolism_Homo sapiens_hsa006501.24962993
22Steroid biosynthesis_Homo sapiens_hsa001001.20086956
23Taurine and hypotaurine metabolism_Homo sapiens_hsa004301.19407640
24Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006011.17192613
25Notch signaling pathway_Homo sapiens_hsa043301.16526659
26Neuroactive ligand-receptor interaction_Homo sapiens_hsa040801.15491991
27Hedgehog signaling pathway_Homo sapiens_hsa043401.11279617
28Morphine addiction_Homo sapiens_hsa050321.09642402
29Peroxisome_Homo sapiens_hsa041461.07811938
30RNA degradation_Homo sapiens_hsa030181.02119651
31Axon guidance_Homo sapiens_hsa043600.99842710
32Insulin secretion_Homo sapiens_hsa049110.99558495
33Ascorbate and aldarate metabolism_Homo sapiens_hsa000530.98253161
34Homologous recombination_Homo sapiens_hsa034400.95544207
35Tryptophan metabolism_Homo sapiens_hsa003800.95329793
36Protein export_Homo sapiens_hsa030600.94217823
37Fanconi anemia pathway_Homo sapiens_hsa034600.93029939
38Basal transcription factors_Homo sapiens_hsa030220.90950017
39Ether lipid metabolism_Homo sapiens_hsa005650.89175142
40Glutamatergic synapse_Homo sapiens_hsa047240.88802776
41Arachidonic acid metabolism_Homo sapiens_hsa005900.88066049
42Propanoate metabolism_Homo sapiens_hsa006400.84638187
43Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.83987696
44Carbohydrate digestion and absorption_Homo sapiens_hsa049730.83019277
45Caffeine metabolism_Homo sapiens_hsa002320.79906592
46GABAergic synapse_Homo sapiens_hsa047270.79824106
47Retrograde endocannabinoid signaling_Homo sapiens_hsa047230.79619738
48Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006300.78933831
49Valine, leucine and isoleucine degradation_Homo sapiens_hsa002800.75046678
50Steroid hormone biosynthesis_Homo sapiens_hsa001400.73985620
51Fatty acid degradation_Homo sapiens_hsa000710.73561434
52Olfactory transduction_Homo sapiens_hsa047400.72605847
53Pyrimidine metabolism_Homo sapiens_hsa002400.70196925
54Nucleotide excision repair_Homo sapiens_hsa034200.70140004
55Ovarian steroidogenesis_Homo sapiens_hsa049130.69828879
56Chemical carcinogenesis_Homo sapiens_hsa052040.68896260
57Metabolic pathways_Homo sapiens_hsa011000.65882051
58Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.65264190
59Serotonergic synapse_Homo sapiens_hsa047260.64820296
60Vasopressin-regulated water reabsorption_Homo sapiens_hsa049620.61723681
61Cholinergic synapse_Homo sapiens_hsa047250.61365654
62Dopaminergic synapse_Homo sapiens_hsa047280.60558264
63Arginine and proline metabolism_Homo sapiens_hsa003300.60474190
64Hippo signaling pathway_Homo sapiens_hsa043900.58116617
65Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004000.57575864
66Synaptic vesicle cycle_Homo sapiens_hsa047210.55226468
67beta-Alanine metabolism_Homo sapiens_hsa004100.55062954
68Circadian entrainment_Homo sapiens_hsa047130.53608346
69Nitrogen metabolism_Homo sapiens_hsa009100.52167073
70Glycerolipid metabolism_Homo sapiens_hsa005610.52062882
71Retinol metabolism_Homo sapiens_hsa008300.51507126
72Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.50834092
73Taste transduction_Homo sapiens_hsa047420.48906262
74Drug metabolism - cytochrome P450_Homo sapiens_hsa009820.48668729
75Folate biosynthesis_Homo sapiens_hsa007900.45697006
76Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005340.45547457
77Starch and sucrose metabolism_Homo sapiens_hsa005000.44971643
78Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010400.42800023
79Cyanoamino acid metabolism_Homo sapiens_hsa004600.41226863
80Oxytocin signaling pathway_Homo sapiens_hsa049210.40880692
81Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.39789310
82Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.38946690
83Fatty acid metabolism_Homo sapiens_hsa012120.38876691
84Salivary secretion_Homo sapiens_hsa049700.37723589
85Primary bile acid biosynthesis_Homo sapiens_hsa001200.37133127
86Cocaine addiction_Homo sapiens_hsa050300.36698349
87Ras signaling pathway_Homo sapiens_hsa040140.36541456
88Thyroid hormone synthesis_Homo sapiens_hsa049180.35288567
89Aldosterone synthesis and secretion_Homo sapiens_hsa049250.34985362
90Mismatch repair_Homo sapiens_hsa034300.32206837
91Melanogenesis_Homo sapiens_hsa049160.32088740
92Dorso-ventral axis formation_Homo sapiens_hsa043200.30580350
93Dilated cardiomyopathy_Homo sapiens_hsa054140.30011328
94Collecting duct acid secretion_Homo sapiens_hsa049660.28284669
95One carbon pool by folate_Homo sapiens_hsa006700.27735685
96Pentose and glucuronate interconversions_Homo sapiens_hsa000400.27698746
97Wnt signaling pathway_Homo sapiens_hsa043100.27017272
98Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049610.26632745
99Bile secretion_Homo sapiens_hsa049760.26403737
100cAMP signaling pathway_Homo sapiens_hsa040240.26276963

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