RPL12P38

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1ATP synthesis coupled proton transport (GO:0015986)5.13933065
2energy coupled proton transport, down electrochemical gradient (GO:0015985)5.13933065
3mitochondrial ATP synthesis coupled proton transport (GO:0042776)4.95902780
4DNA deamination (GO:0045006)4.88043834
5protein complex biogenesis (GO:0070271)4.75191641
6establishment of protein localization to mitochondrial membrane (GO:0090151)4.69320483
7mitochondrial respiratory chain complex I biogenesis (GO:0097031)4.51506128
8mitochondrial respiratory chain complex I assembly (GO:0032981)4.51506128
9NADH dehydrogenase complex assembly (GO:0010257)4.51506128
10mitochondrial respiratory chain complex assembly (GO:0033108)4.35920045
11ribosomal small subunit assembly (GO:0000028)4.32597872
12mitochondrial electron transport, NADH to ubiquinone (GO:0006120)4.21799369
13protein neddylation (GO:0045116)4.03458805
14chaperone-mediated protein transport (GO:0072321)3.99550169
15nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291)3.95245632
16maturation of SSU-rRNA (GO:0030490)3.93452314
17RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394)3.93116593
18tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388)3.93116593
19exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay 3.87927284
20behavioral response to nicotine (GO:0035095)3.84502871
21viral transcription (GO:0019083)3.81521692
22water-soluble vitamin biosynthetic process (GO:0042364)3.78805751
23respiratory electron transport chain (GO:0022904)3.76500547
24translational termination (GO:0006415)3.76204300
25electron transport chain (GO:0022900)3.74960426
26SRP-dependent cotranslational protein targeting to membrane (GO:0006614)3.65638128
27regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:00450913.62451509
28cotranslational protein targeting to membrane (GO:0006613)3.61599366
29protein targeting to ER (GO:0045047)3.56755102
30cytochrome complex assembly (GO:0017004)3.40523690
31establishment of protein localization to endoplasmic reticulum (GO:0072599)3.40319064
32protein localization to endoplasmic reticulum (GO:0070972)3.39687742
33platelet dense granule organization (GO:0060155)3.37438254
34protein-cofactor linkage (GO:0018065)3.35418459
35translational elongation (GO:0006414)3.34948040
36proteasome assembly (GO:0043248)3.34889902
37respiratory chain complex IV assembly (GO:0008535)3.31893864
38preassembly of GPI anchor in ER membrane (GO:0016254)3.31569411
39mannosylation (GO:0097502)3.31271991
40ribosomal large subunit biogenesis (GO:0042273)3.26572554
41termination of RNA polymerase III transcription (GO:0006386)3.15186181
42transcription elongation from RNA polymerase III promoter (GO:0006385)3.15186181
43maturation of 5.8S rRNA (GO:0000460)3.13918824
44translation (GO:0006412)3.12815873
45ribosomal small subunit biogenesis (GO:0042274)3.11150152
46chromatin remodeling at centromere (GO:0031055)3.10638195
47regulation of mitotic spindle checkpoint (GO:1903504)3.06528206
48regulation of mitotic cell cycle spindle assembly checkpoint (GO:0090266)3.06528206
49pyrimidine deoxyribonucleotide catabolic process (GO:0009223)3.05868310
50protein deneddylation (GO:0000338)3.02396211
51cullin deneddylation (GO:0010388)3.01387288
52GPI anchor metabolic process (GO:0006505)3.00042715
53regulation of mitochondrial translation (GO:0070129)2.97356777
54cellular component biogenesis (GO:0044085)2.96690293
55ATP biosynthetic process (GO:0006754)2.94606027
56pseudouridine synthesis (GO:0001522)2.94567777
57purine nucleoside triphosphate biosynthetic process (GO:0009145)2.94335822
58purine ribonucleoside triphosphate biosynthetic process (GO:0009206)2.92967353
59CENP-A containing nucleosome assembly (GO:0034080)2.92215098
60GPI anchor biosynthetic process (GO:0006506)2.90505569
61tRNA processing (GO:0008033)2.88274792
62GTP biosynthetic process (GO:0006183)2.87778219
63hydrogen ion transmembrane transport (GO:1902600)2.86991837
64viral life cycle (GO:0019058)2.86825219
65cytidine metabolic process (GO:0046087)2.86334302
66cytidine catabolic process (GO:0006216)2.86334302
67cytidine deamination (GO:0009972)2.86334302
68translational initiation (GO:0006413)2.83645617
69response to pheromone (GO:0019236)2.83258032
70fucose catabolic process (GO:0019317)2.82788017
71L-fucose metabolic process (GO:0042354)2.82788017
72L-fucose catabolic process (GO:0042355)2.82788017
73RNA phosphodiester bond hydrolysis, exonucleolytic (GO:0090503)2.79807062
74cellular protein complex disassembly (GO:0043624)2.77048541
75proton transport (GO:0015992)2.75989512
76piRNA metabolic process (GO:0034587)2.75825635
77L-methionine biosynthetic process from methylthioadenosine (GO:0019509)2.73843734
78nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184)2.72183503
79DNA double-strand break processing (GO:0000729)2.70958608
80hydrogen transport (GO:0006818)2.70712677
81negative regulation of telomere maintenance (GO:0032205)2.67499620
82base-excision repair, AP site formation (GO:0006285)2.65012069
83indolalkylamine metabolic process (GO:0006586)2.63430221
84rRNA processing (GO:0006364)2.63277096
85rRNA metabolic process (GO:0016072)2.63177569
86intracellular protein transmembrane import (GO:0044743)2.61690595
87metallo-sulfur cluster assembly (GO:0031163)2.61433880
88iron-sulfur cluster assembly (GO:0016226)2.61433880
89negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436)2.58778475
90kynurenine metabolic process (GO:0070189)2.58715687
91ubiquinone biosynthetic process (GO:0006744)2.58502255
92rRNA modification (GO:0000154)2.58446795
93DNA replication checkpoint (GO:0000076)2.57478354
94ribonucleoside triphosphate biosynthetic process (GO:0009201)2.56869533
95pyrimidine deoxyribonucleotide metabolic process (GO:0009219)2.55021822
96tryptophan catabolic process (GO:0006569)2.54235408
97indole-containing compound catabolic process (GO:0042436)2.54235408
98indolalkylamine catabolic process (GO:0046218)2.54235408
99oxidative phosphorylation (GO:0006119)2.52098108
100peptidyl-histidine modification (GO:0018202)2.51587437

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human4.33362498
2GABP_17652178_ChIP-ChIP_JURKAT_Human4.23412051
3EST1_17652178_ChIP-ChIP_JURKAT_Human3.65349102
4HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human3.29273118
5SOX9_22984422_ChIP-ChIP_TESTIS_Rat3.22361389
6ELF1_17652178_ChIP-ChIP_JURKAT_Human2.98378798
7JARID1A_20064375_ChIP-Seq_MESCs_Mouse2.90441214
8ZNF274_21170338_ChIP-Seq_K562_Hela2.82635071
9VDR_22108803_ChIP-Seq_LS180_Human2.80711722
10MYCN_21190229_ChIP-Seq_SHEP-21N_Human2.73897921
11ETS1_20019798_ChIP-Seq_JURKAT_Human2.68378604
12VDR_23849224_ChIP-Seq_CD4+_Human2.63316114
13NOTCH1_17114293_ChIP-ChIP_T-ALL_Human2.61895889
14ELK1_19687146_ChIP-ChIP_HELA_Human2.52377052
15CHD1_19587682_ChIP-ChIP_MESCs_Mouse2.39102911
16MYC_18940864_ChIP-ChIP_HL60_Human2.29675933
17CREB1_15753290_ChIP-ChIP_HEK293T_Human2.23612509
18FOXP3_21729870_ChIP-Seq_TREG_Human2.20193757
19IGF1R_20145208_ChIP-Seq_DFB_Human2.11701003
20MYC_18555785_ChIP-Seq_MESCs_Mouse2.10380445
21E2F4_17652178_ChIP-ChIP_JURKAT_Human2.09175438
22EWS_26573619_Chip-Seq_HEK293_Human1.98758302
23SRF_21415370_ChIP-Seq_HL-1_Mouse1.98321755
24E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse1.86973794
25NOTCH1_21737748_ChIP-Seq_TLL_Human1.83626201
26FLI1_27457419_Chip-Seq_LIVER_Mouse1.82128164
27FUS_26573619_Chip-Seq_HEK293_Human1.75379418
28EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human1.63664572
29TTF2_22483619_ChIP-Seq_HELA_Human1.62389582
30PDX1_19855005_ChIP-ChIP_MIN6_Mouse1.61125862
31IRF1_19129219_ChIP-ChIP_H3396_Human1.57860164
32HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse1.54564409
33MYC_18358816_ChIP-ChIP_MESCs_Mouse1.53950871
34FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse1.50003407
35TP53_22573176_ChIP-Seq_HFKS_Human1.49444233
36GABP_19822575_ChIP-Seq_HepG2_Human1.44948286
37CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human1.43496093
38POU3F2_20337985_ChIP-ChIP_501MEL_Human1.42181101
39PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse1.40684785
40ZFP57_27257070_Chip-Seq_ESCs_Mouse1.37421633
41POU5F1_18358816_ChIP-ChIP_MESCs_Mouse1.36615079
42CTBP1_25329375_ChIP-Seq_LNCAP_Human1.36090070
43PCGF2_27294783_Chip-Seq_ESCs_Mouse1.35823419
44MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human1.35696864
45HCFC1_20581084_ChIP-Seq_MESCs_Mouse1.31120404
46FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse1.30653057
47FOXA1_25329375_ChIP-Seq_VCAP_Human1.29866285
48FOXA1_27270436_Chip-Seq_PROSTATE_Human1.29866285
49PADI4_21655091_ChIP-ChIP_MCF-7_Human1.28692291
50TAF15_26573619_Chip-Seq_HEK293_Human1.27489956
51AR_20517297_ChIP-Seq_VCAP_Human1.26551192
52YY1_21170310_ChIP-Seq_MESCs_Mouse1.26368203
53MYC_19030024_ChIP-ChIP_MESCs_Mouse1.22727954
54DCP1A_22483619_ChIP-Seq_HELA_Human1.22618936
55P300_19829295_ChIP-Seq_ESCs_Human1.21406424
56CEBPB_23403033_ChIP-Seq_LIVER_Mouse1.20657110
57FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human1.18489486
58XRN2_22483619_ChIP-Seq_HELA_Human1.17618851
59BMI1_23680149_ChIP-Seq_NPCS_Mouse1.16139586
60AUTS2_25519132_ChIP-Seq_293T-REX_Human1.16081797
61GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse1.15039112
62HOXB4_20404135_ChIP-ChIP_EML_Mouse1.13681255
63E2F1_18555785_ChIP-Seq_MESCs_Mouse1.13451869
64IRF4_20064451_ChIP-Seq_CD4+T_Mouse1.12647724
65CBP_20019798_ChIP-Seq_JUKART_Human1.12647724
66EZH2_22144423_ChIP-Seq_EOC_Human1.12159013
67POU5F1_16153702_ChIP-ChIP_HESCs_Human1.11547106
68ER_23166858_ChIP-Seq_MCF-7_Human1.09822432
69NCOR_22424771_ChIP-Seq_293T_Human1.09341096
70THAP11_20581084_ChIP-Seq_MESCs_Mouse1.08294714
71PCGF2_27294783_Chip-Seq_NPCs_Mouse1.07945702
72CTBP2_25329375_ChIP-Seq_LNCAP_Human1.06518767
73CIITA_25753668_ChIP-Seq_RAJI_Human1.06474292
74NANOG_19829295_ChIP-Seq_ESCs_Human1.05232159
75SOX2_19829295_ChIP-Seq_ESCs_Human1.05232159
76GATA3_21878914_ChIP-Seq_MCF-7_Human1.01295673
77PAX6_23342162_ChIP-ChIP_BETA-FORBRAIN-LENS_Mouse1.00533041
78GATA3_26560356_Chip-Seq_TH2_Human1.00507149
79CEBPA_26348894_ChIP-Seq_LIVER_Mouse1.00192974
80ZFP42_18358816_ChIP-ChIP_MESCs_Mouse1.00049422
81MYC_19079543_ChIP-ChIP_MESCs_Mouse0.98735084
82ELK1_22589737_ChIP-Seq_MCF10A_Human0.98513388
83GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.98406939
84HTT_18923047_ChIP-ChIP_STHdh_Human0.95116260
85GLI1_17442700_ChIP-ChIP_MESCs_Mouse0.94627686
86HOXB7_26014856_ChIP-Seq_BT474_Human0.93210743
87FOXP2_21765815_ChIP-ChIP_NEURO2A_Mouse0.93068147
88FOXA1_21572438_ChIP-Seq_LNCaP_Human0.92327784
89ETV2_25802403_ChIP-Seq_MESCs_Mouse0.91726853
90NANOG_20526341_ChIP-Seq_ESCs_Human0.91538629
91PBX1_22567123_ChIP-ChIP_OVCAR3_Human0.90892819
92CHD7_19251738_ChIP-ChIP_MESCs_Mouse0.89821773
93NFE2_27457419_Chip-Seq_LIVER_Mouse0.89722289
94FLI1_20887958_ChIP-Seq_HPC-7_Mouse0.89125265
95FOXH1_21741376_ChIP-Seq_EPCs_Human0.88835207
96MYBL2_22936984_ChIP-ChIP_MESCs_Mouse0.88559052
97SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse0.88522056
98CEBPB_24764292_ChIP-Seq_MC3T3_Mouse0.88198196
99TAF2_19829295_ChIP-Seq_ESCs_Human0.86832864
100UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human0.86473173

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0006292_abnormal_olfactory_placode3.82829347
2MP0009379_abnormal_foot_pigmentation3.53615245
3MP0008877_abnormal_DNA_methylation2.96179351
4MP0006072_abnormal_retinal_apoptosis2.72794875
5MP0002102_abnormal_ear_morphology2.62231056
6MP0002837_dystrophic_cardiac_calcinosis2.35637472
7MP0005671_abnormal_response_to2.19555373
8MP0004147_increased_porphyrin_level1.94281503
9MP0002163_abnormal_gland_morphology1.93442253
10MP0008058_abnormal_DNA_repair1.93326021
11MP0001529_abnormal_vocalization1.91759160
12MP0003787_abnormal_imprinting1.91490421
13MP0004142_abnormal_muscle_tone1.85837648
14MP0005551_abnormal_eye_electrophysiolog1.80672145
15MP0002234_abnormal_pharynx_morphology1.74833601
16MP0005646_abnormal_pituitary_gland1.72859355
17MP0005084_abnormal_gallbladder_morpholo1.72566405
18MP0002736_abnormal_nociception_after1.71280923
19MP0005645_abnormal_hypothalamus_physiol1.66797667
20MP0008789_abnormal_olfactory_epithelium1.64715022
21MP0008875_abnormal_xenobiotic_pharmacok1.62484615
22MP0003786_premature_aging1.61648147
23MP0003646_muscle_fatigue1.60008282
24MP0008872_abnormal_physiological_respon1.58047279
25MP0003693_abnormal_embryo_hatching1.57844171
26MP0001968_abnormal_touch/_nociception1.54749395
27MP0002876_abnormal_thyroid_physiology1.54658495
28MP0000372_irregular_coat_pigmentation1.51103835
29MP0003195_calcinosis1.50899834
30MP0004885_abnormal_endolymph1.47563348
31MP0005389_reproductive_system_phenotype1.47204400
32MP0005253_abnormal_eye_physiology1.47021601
33MP0005379_endocrine/exocrine_gland_phen1.44591934
34MP0002653_abnormal_ependyma_morphology1.44336677
35MP0005075_abnormal_melanosome_morpholog1.43461529
36MP0001293_anophthalmia1.42430268
37MP0003806_abnormal_nucleotide_metabolis1.42277876
38MP0001188_hyperpigmentation1.41978119
39MP0010094_abnormal_chromosome_stability1.38300955
40MP0001905_abnormal_dopamine_level1.38189300
41MP0002938_white_spotting1.37265852
42MP0003880_abnormal_central_pattern1.36512102
43MP0003011_delayed_dark_adaptation1.35183311
44MP0001986_abnormal_taste_sensitivity1.32656545
45MP0000631_abnormal_neuroendocrine_gland1.28734900
46MP0002277_abnormal_respiratory_mucosa1.27056243
47MP0006036_abnormal_mitochondrial_physio1.25375317
48MP0008995_early_reproductive_senescence1.24688734
49MP0001919_abnormal_reproductive_system1.23479581
50MP0001835_abnormal_antigen_presentation1.23240494
51MP0002138_abnormal_hepatobiliary_system1.20155231
52MP0003567_abnormal_fetal_cardiomyocyte1.19475066
53MP0002160_abnormal_reproductive_system1.19055573
54MP0006276_abnormal_autonomic_nervous1.18471869
55MP0001984_abnormal_olfaction1.17776435
56MP0002272_abnormal_nervous_system1.15990411
57MP0001485_abnormal_pinna_reflex1.15213476
58MP0002095_abnormal_skin_pigmentation1.14450363
59MP0000049_abnormal_middle_ear1.12056529
60MP0002638_abnormal_pupillary_reflex1.11156617
61MP0003718_maternal_effect1.09217861
62MP0009745_abnormal_behavioral_response1.08043284
63MP0009046_muscle_twitch1.06361338
64MP0003186_abnormal_redox_activity1.06360306
65MP0005394_taste/olfaction_phenotype1.05275850
66MP0005499_abnormal_olfactory_system1.05275850
67MP0000427_abnormal_hair_cycle1.01033906
68MP0005332_abnormal_amino_acid0.99598756
69MP0005174_abnormal_tail_pigmentation0.99062655
70MP0003121_genomic_imprinting0.98191389
71MP0006035_abnormal_mitochondrial_morpho0.98032775
72MP0004145_abnormal_muscle_electrophysio0.96686743
73MP0003878_abnormal_ear_physiology0.94072719
74MP0005377_hearing/vestibular/ear_phenot0.94072719
75MP0001764_abnormal_homeostasis0.92200125
76MP0002148_abnormal_hypersensitivity_rea0.91825834
77MP0003283_abnormal_digestive_organ0.91369552
78MP0002210_abnormal_sex_determination0.90142169
79MP0005195_abnormal_posterior_eye0.88906551
80MP0001929_abnormal_gametogenesis0.87412884
81MP0000685_abnormal_immune_system0.86141791
82MP0004957_abnormal_blastocyst_morpholog0.84475433
83MP0003122_maternal_imprinting0.82144286
84MP0000653_abnormal_sex_gland0.80572715
85MP0002751_abnormal_autonomic_nervous0.80165450
86MP0002733_abnormal_thermal_nociception0.78878533
87MP0001145_abnormal_male_reproductive0.77946558
88MP0005410_abnormal_fertilization0.77233516
89MP0001486_abnormal_startle_reflex0.76823997
90MP0003252_abnormal_bile_duct0.75973218
91MP0005636_abnormal_mineral_homeostasis0.75943425
92MP0001970_abnormal_pain_threshold0.73127889
93MP0001119_abnormal_female_reproductive0.72001267
94MP0003866_abnormal_defecation0.71607549
95MP0004133_heterotaxia0.71572115
96MP0009764_decreased_sensitivity_to0.71088202
97MP0001800_abnormal_humoral_immune0.69822481
98MP0009785_altered_susceptibility_to0.68435571
99MP0002557_abnormal_social/conspecific_i0.66829104
100MP0001501_abnormal_sleep_pattern0.65756336

Predicted human phenotypes

RankGene SetZ-score
1Acute necrotizing encephalopathy (HP:0006965)4.37081402
2Mitochondrial inheritance (HP:0001427)4.04427487
3Abnormal mitochondria in muscle tissue (HP:0008316)3.90501963
4Increased CSF lactate (HP:0002490)3.76509034
5Acute encephalopathy (HP:0006846)3.73414930
6Progressive macrocephaly (HP:0004481)3.73395252
7Hepatocellular necrosis (HP:0001404)3.52541678
8Pancreatic cysts (HP:0001737)3.51707863
93-Methylglutaconic aciduria (HP:0003535)3.42867573
10Abnormality of midbrain morphology (HP:0002418)3.33140291
11Molar tooth sign on MRI (HP:0002419)3.33140291
12Hepatic necrosis (HP:0002605)3.32640871
13Increased hepatocellular lipid droplets (HP:0006565)3.23944218
14Pancreatic fibrosis (HP:0100732)3.14661729
15Lipid accumulation in hepatocytes (HP:0006561)3.13352757
16True hermaphroditism (HP:0010459)3.03623110
17Cerebral edema (HP:0002181)3.02804850
18Congenital stationary night blindness (HP:0007642)3.02514997
19Absent rod-and cone-mediated responses on ERG (HP:0007688)2.87605109
20Increased serum lactate (HP:0002151)2.80578251
21Congenital, generalized hypertrichosis (HP:0004540)2.75956329
22Abnormal rod and cone electroretinograms (HP:0008323)2.74923740
23Methylmalonic acidemia (HP:0002912)2.74149670
24Abnormality of pyruvate family amino acid metabolism (HP:0010915)2.71789127
25Abnormality of alanine metabolism (HP:0010916)2.71789127
26Hyperalaninemia (HP:0003348)2.71789127
27Nephronophthisis (HP:0000090)2.69194637
28Pendular nystagmus (HP:0012043)2.68146527
29Reticulocytopenia (HP:0001896)2.66682281
30Abnormality of cells of the erythroid lineage (HP:0012130)2.64388986
31Optic disc pallor (HP:0000543)2.63182774
32Abolished electroretinogram (ERG) (HP:0000550)2.61439961
33Medial flaring of the eyebrow (HP:0010747)2.60357542
34Lactic acidosis (HP:0003128)2.57363680
35Abnormal number of erythroid precursors (HP:0012131)2.55310354
36Renal Fanconi syndrome (HP:0001994)2.50289808
37Type II lissencephaly (HP:0007260)2.44951706
38Sclerocornea (HP:0000647)2.37144270
39IgG deficiency (HP:0004315)2.34560020
40Colon cancer (HP:0003003)2.33801756
41Abnormal activity of mitochondrial respiratory chain (HP:0011922)2.33160891
42Decreased activity of mitochondrial respiratory chain (HP:0008972)2.33160891
43Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688)2.30352605
44Decreased electroretinogram (ERG) amplitude (HP:0000654)2.28093568
45Macrocytic anemia (HP:0001972)2.27362531
46Absent thumb (HP:0009777)2.26352792
47Methylmalonic aciduria (HP:0012120)2.26214032
48Increased intramyocellular lipid droplets (HP:0012240)2.25654722
49Respiratory failure (HP:0002878)2.19737193
50Lethargy (HP:0001254)2.17604842
51Exertional dyspnea (HP:0002875)2.15917797
52Attenuation of retinal blood vessels (HP:0007843)2.14216828
53Abnormality of the renal cortex (HP:0011035)2.13344599
54Abnormality of the renal medulla (HP:0100957)2.09697579
55Renal cortical cysts (HP:0000803)2.03205438
56Hyperglycinemia (HP:0002154)2.01216239
57Aplasia/hypoplasia of the uterus (HP:0008684)2.00341100
58Absent/shortened dynein arms (HP:0200106)1.99525833
59Dynein arm defect of respiratory motile cilia (HP:0012255)1.99525833
60Decreased central vision (HP:0007663)1.95836493
61Muscle abnormality related to mitochondrial dysfunction (HP:0003800)1.95741870
62Type I transferrin isoform profile (HP:0003642)1.94517604
63Cystic liver disease (HP:0006706)1.94322680
64Abnormality of urine glucose concentration (HP:0011016)1.94317103
65Glycosuria (HP:0003076)1.94317103
66Congenital primary aphakia (HP:0007707)1.92097889
67Leukodystrophy (HP:0002415)1.91215525
68Abnormality of the renal collecting system (HP:0004742)1.87660019
69Gait imbalance (HP:0002141)1.86595262
70Increased muscle lipid content (HP:0009058)1.85317581
71Nephrogenic diabetes insipidus (HP:0009806)1.83630707
72Severe combined immunodeficiency (HP:0004430)1.83086277
73Aplasia/Hypoplasia of the spleen (HP:0010451)1.82204142
74Abnormality of the labia minora (HP:0012880)1.82070173
75Exercise intolerance (HP:0003546)1.82052470
76Type 2 muscle fiber atrophy (HP:0003554)1.81476709
77Postaxial foot polydactyly (HP:0001830)1.80776673
78Abnormality of the prostate (HP:0008775)1.80422498
79Abnormality of serum amino acid levels (HP:0003112)1.79741617
80Abnormality of renal resorption (HP:0011038)1.79534859
81Progressive microcephaly (HP:0000253)1.78348078
82Anencephaly (HP:0002323)1.75822157
83Keratoconus (HP:0000563)1.75188465
84Increased corneal curvature (HP:0100692)1.75188465
85Pancytopenia (HP:0001876)1.74130187
86Abnormality of vitamin B metabolism (HP:0004340)1.73778141
87Asplenia (HP:0001746)1.73707356
88Short tibia (HP:0005736)1.73611351
89Aplasia/Hypoplasia of the uvula (HP:0010293)1.73400838
90Aplastic anemia (HP:0001915)1.72815139
91Male pseudohermaphroditism (HP:0000037)1.72711863
92Hypoplasia of the uterus (HP:0000013)1.72370778
93Aplasia/Hypoplasia of the tongue (HP:0010295)1.72300502
94Pallor (HP:0000980)1.71965033
95Abnormal protein glycosylation (HP:0012346)1.71780192
96Abnormal glycosylation (HP:0012345)1.71780192
97Abnormal isoelectric focusing of serum transferrin (HP:0003160)1.71780192
98Abnormal protein N-linked glycosylation (HP:0012347)1.71780192
99Constricted visual fields (HP:0001133)1.70943753
100Elevated erythrocyte sedimentation rate (HP:0003565)1.70680339

Predicted kinase interactions (KEA)

RankGene SetZ-score
1VRK23.67556889
2MAP4K23.19785676
3BCKDK3.16690681
4FRK2.85992373
5ZAK2.81078760
6NUAK12.79546685
7TLK12.57942534
8TXK2.42707217
9STK162.29283399
10TAOK32.23454079
11BUB12.20910056
12ADRBK22.07782346
13BMPR1B2.03172400
14GRK11.97595640
15TAF11.91987200
16EIF2AK31.89041944
17CDK191.76379070
18WNK31.72697525
19VRK11.68839377
20CDC71.46916722
21PLK41.42908700
22TRIM281.41246496
23PINK11.39602646
24WNK41.29758347
25MST41.28211900
26CSNK1G31.24821515
27NEK11.22956747
28DYRK21.22199903
29EIF2AK11.22073405
30PLK31.18929354
31MAP3K121.13399639
32CDK81.12913940
33OXSR11.09971651
34SRPK11.06869873
35CSNK1G21.06639541
36TIE11.04055267
37CSNK1G10.99036013
38ERBB30.98570257
39RPS6KA40.98380315
40INSRR0.95819779
41PLK20.95131667
42KDR0.94990340
43EIF2AK20.94306261
44TESK20.89246286
45WEE10.89026498
46CSNK1A1L0.88250234
47KIT0.87202271
48MAPK130.84493753
49MKNK20.84275788
50LIMK10.82938544
51ACVR1B0.81937000
52MKNK10.81288383
53TEC0.80539604
54PHKG20.80429853
55PHKG10.80429853
56PLK10.75664040
57GRK60.73513383
58RPS6KA50.72647990
59PASK0.72535674
60ATR0.72378960
61BCR0.70588087
62IKBKB0.67613394
63MAPKAPK50.67008142
64GRK50.66511833
65MAP3K40.65547287
66STK390.64030162
67AURKB0.63780932
68DAPK10.63762164
69MAP2K70.62974915
70GRK70.62883787
71CHEK20.62015597
72PRKCI0.61071352
73SYK0.60887686
74NME10.60201030
75PRKCG0.59922660
76PRKCE0.59778734
77MAPKAPK30.59260694
78BRSK20.58998857
79ITK0.56500316
80ADRBK10.55667947
81PRKCQ0.54341135
82TGFBR10.53579690
83CSNK2A10.53510359
84NEK20.51144084
85NME20.51130832
86CSNK2A20.46264735
87TNIK0.45907118
88PIK3CA0.45107159
89AURKA0.44862804
90MAP4K10.42162197
91BMPR20.41211216
92MAP2K20.41057443
93CSNK1A10.39615468
94MAP2K60.38871037
95TTK0.38113406
96PRKACA0.37607354
97ILK0.37424330
98FLT30.36757238
99DAPK20.35814178
100LYN0.35418511

Predicted pathways (KEGG)

RankGene SetZ-score
1Ribosome_Homo sapiens_hsa030103.81422889
2Oxidative phosphorylation_Homo sapiens_hsa001903.75690424
3Protein export_Homo sapiens_hsa030603.18917542
4Proteasome_Homo sapiens_hsa030503.13749880
5Parkinsons disease_Homo sapiens_hsa050123.09426885
6RNA polymerase_Homo sapiens_hsa030202.50505851
7Homologous recombination_Homo sapiens_hsa034402.22895040
8Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005632.18087409
9Asthma_Homo sapiens_hsa053102.10549550
10Huntingtons disease_Homo sapiens_hsa050162.06669493
11Alzheimers disease_Homo sapiens_hsa050101.99297949
12Mismatch repair_Homo sapiens_hsa034301.90592516
13Intestinal immune network for IgA production_Homo sapiens_hsa046721.89142862
14RNA degradation_Homo sapiens_hsa030181.85542855
15DNA replication_Homo sapiens_hsa030301.83936112
16Fanconi anemia pathway_Homo sapiens_hsa034601.80631606
17Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030081.76141847
18Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049321.72091533
19Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001301.68289118
20Synthesis and degradation of ketone bodies_Homo sapiens_hsa000721.66900750
21Phototransduction_Homo sapiens_hsa047441.66026204
22Basal transcription factors_Homo sapiens_hsa030221.60127827
23Sulfur relay system_Homo sapiens_hsa041221.57888720
24Cardiac muscle contraction_Homo sapiens_hsa042601.53893971
25Graft-versus-host disease_Homo sapiens_hsa053321.52312328
26Allograft rejection_Homo sapiens_hsa053301.51683956
27Pyrimidine metabolism_Homo sapiens_hsa002401.51185944
28Type I diabetes mellitus_Homo sapiens_hsa049401.49398939
29Caffeine metabolism_Homo sapiens_hsa002321.48994584
30Autoimmune thyroid disease_Homo sapiens_hsa053201.47859127
31Linoleic acid metabolism_Homo sapiens_hsa005911.44952382
32Nucleotide excision repair_Homo sapiens_hsa034201.38709073
33One carbon pool by folate_Homo sapiens_hsa006701.35889703
34Cytosolic DNA-sensing pathway_Homo sapiens_hsa046231.31718453
35Spliceosome_Homo sapiens_hsa030401.29570734
36Propanoate metabolism_Homo sapiens_hsa006401.28546554
37alpha-Linolenic acid metabolism_Homo sapiens_hsa005921.25354902
38Base excision repair_Homo sapiens_hsa034101.22796402
39Valine, leucine and isoleucine degradation_Homo sapiens_hsa002801.22721921
40Primary immunodeficiency_Homo sapiens_hsa053401.21555951
41Tryptophan metabolism_Homo sapiens_hsa003801.13407526
42Purine metabolism_Homo sapiens_hsa002301.11515571
43RNA transport_Homo sapiens_hsa030131.11263077
44Sulfur metabolism_Homo sapiens_hsa009201.10105347
45Butanoate metabolism_Homo sapiens_hsa006501.07075139
46Non-homologous end-joining_Homo sapiens_hsa034501.02770756
47Fatty acid elongation_Homo sapiens_hsa000621.01350583
48Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.99101911
49Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.97616254
50Antigen processing and presentation_Homo sapiens_hsa046120.97294498
51Maturity onset diabetes of the young_Homo sapiens_hsa049500.95123974
52Nitrogen metabolism_Homo sapiens_hsa009100.92630322
53Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006300.91435126
54Peroxisome_Homo sapiens_hsa041460.90253268
55Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.87399333
56Selenocompound metabolism_Homo sapiens_hsa004500.87089964
57Regulation of autophagy_Homo sapiens_hsa041400.86192820
58Taurine and hypotaurine metabolism_Homo sapiens_hsa004300.83244061
59Arachidonic acid metabolism_Homo sapiens_hsa005900.82292208
60Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009700.81922935
61Cysteine and methionine metabolism_Homo sapiens_hsa002700.81591526
62Chemical carcinogenesis_Homo sapiens_hsa052040.78685059
63Ether lipid metabolism_Homo sapiens_hsa005650.76020865
64Rheumatoid arthritis_Homo sapiens_hsa053230.74631989
65Folate biosynthesis_Homo sapiens_hsa007900.70753636
66Metabolic pathways_Homo sapiens_hsa011000.68310260
67Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.66565778
68Olfactory transduction_Homo sapiens_hsa047400.66218602
69Collecting duct acid secretion_Homo sapiens_hsa049660.65781930
70Inflammatory bowel disease (IBD)_Homo sapiens_hsa053210.62784585
71Retinol metabolism_Homo sapiens_hsa008300.59213325
72Nicotine addiction_Homo sapiens_hsa050330.59003692
73Drug metabolism - cytochrome P450_Homo sapiens_hsa009820.58574220
74Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.55689609
75Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.53597450
76SNARE interactions in vesicular transport_Homo sapiens_hsa041300.52875871
77Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.51288711
78Drug metabolism - other enzymes_Homo sapiens_hsa009830.49682740
79Glutathione metabolism_Homo sapiens_hsa004800.48229725
80Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.46325500
81Fat digestion and absorption_Homo sapiens_hsa049750.45974472
82Steroid hormone biosynthesis_Homo sapiens_hsa001400.44165767
83Ascorbate and aldarate metabolism_Homo sapiens_hsa000530.40186412
84Systemic lupus erythematosus_Homo sapiens_hsa053220.40004987
85Pentose and glucuronate interconversions_Homo sapiens_hsa000400.38788823
86Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.37544861
87Cytokine-cytokine receptor interaction_Homo sapiens_hsa040600.37345915
88Pyruvate metabolism_Homo sapiens_hsa006200.35809544
89Hematopoietic cell lineage_Homo sapiens_hsa046400.34654740
90Taste transduction_Homo sapiens_hsa047420.34639337
91Vitamin digestion and absorption_Homo sapiens_hsa049770.32967491
92p53 signaling pathway_Homo sapiens_hsa041150.32325472
93Primary bile acid biosynthesis_Homo sapiens_hsa001200.30878452
94Morphine addiction_Homo sapiens_hsa050320.29514316
95Fatty acid degradation_Homo sapiens_hsa000710.26853870
96Steroid biosynthesis_Homo sapiens_hsa001000.26785702
97Epstein-Barr virus infection_Homo sapiens_hsa051690.25738441
98Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.24487678
99beta-Alanine metabolism_Homo sapiens_hsa004100.22949477
100Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.21630890

Most similar genes based on co-expression Upload to Enrichr

Tissue Expression Export image »

Cell Line Expression Export image »