RPF1

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1mitochondrial ATP synthesis coupled proton transport (GO:0042776)5.31371995
2ribosomal small subunit assembly (GO:0000028)5.01030570
3chaperone-mediated protein transport (GO:0072321)4.72457432
4energy coupled proton transport, down electrochemical gradient (GO:0015985)4.46148514
5ATP synthesis coupled proton transport (GO:0015986)4.46148514
6DNA deamination (GO:0045006)4.45703557
7maturation of SSU-rRNA (GO:0030490)4.43257630
8regulation of mitochondrial translation (GO:0070129)4.26063552
9DNA strand elongation involved in DNA replication (GO:0006271)4.24455470
10viral transcription (GO:0019083)4.24434062
11establishment of protein localization to mitochondrial membrane (GO:0090151)4.23191271
12translational termination (GO:0006415)4.22209773
13ribosomal small subunit biogenesis (GO:0042274)4.20470483
14DNA replication initiation (GO:0006270)4.16325859
15nucleobase biosynthetic process (GO:0046112)4.16144672
16purine nucleobase biosynthetic process (GO:0009113)4.10977171
17telomere maintenance via semi-conservative replication (GO:0032201)4.10260271
18formation of translation preinitiation complex (GO:0001731)4.06698456
19DNA strand elongation (GO:0022616)4.04342334
20CENP-A containing nucleosome assembly (GO:0034080)4.00390104
21ribosomal large subunit biogenesis (GO:0042273)3.97662909
22ribonucleoprotein complex biogenesis (GO:0022613)3.96367188
23mitochondrial electron transport, NADH to ubiquinone (GO:0006120)3.94887513
24chromatin remodeling at centromere (GO:0031055)3.89841981
25DNA replication checkpoint (GO:0000076)3.89744343
26ribosome biogenesis (GO:0042254)3.88675526
27negative regulation of ligase activity (GO:0051352)3.87603915
28negative regulation of ubiquitin-protein transferase activity (GO:0051444)3.87603915
29translational elongation (GO:0006414)3.83054496
30establishment of integrated proviral latency (GO:0075713)3.79148579
31telomere maintenance via recombination (GO:0000722)3.78068008
32ribosome assembly (GO:0042255)3.76564967
33translational initiation (GO:0006413)3.75894004
34kinetochore organization (GO:0051383)3.72099422
35respiratory electron transport chain (GO:0022904)3.71527046
36DNA unwinding involved in DNA replication (GO:0006268)3.70200968
37mitotic metaphase plate congression (GO:0007080)3.69678345
38SRP-dependent cotranslational protein targeting to membrane (GO:0006614)3.68448251
39DNA replication-independent nucleosome assembly (GO:0006336)3.63429477
40DNA replication-independent nucleosome organization (GO:0034724)3.63429477
41electron transport chain (GO:0022900)3.62910419
42cullin deneddylation (GO:0010388)3.62112894
43cotranslational protein targeting to membrane (GO:0006613)3.58016718
44protein targeting to ER (GO:0045047)3.57092417
45protein targeting to mitochondrion (GO:0006626)3.56197245
46positive regulation of ubiquitin-protein transferase activity (GO:0051443)3.55337394
47mitotic recombination (GO:0006312)3.55311199
48IMP biosynthetic process (GO:0006188)3.55121365
49folic acid-containing compound biosynthetic process (GO:0009396)3.54772496
50nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184)3.52609184
51DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest (GO:003.52556892
52protein deneddylation (GO:0000338)3.51503333
53proteasome assembly (GO:0043248)3.51335080
54mitotic nuclear envelope disassembly (GO:0007077)3.51034640
55signal transduction involved in mitotic DNA damage checkpoint (GO:1902402)3.50590257
56signal transduction involved in mitotic cell cycle checkpoint (GO:0072413)3.50590257
57signal transduction involved in mitotic DNA integrity checkpoint (GO:1902403)3.50590257
58* rRNA processing (GO:0006364)3.49255368
59intracellular signal transduction involved in G1 DNA damage checkpoint (GO:1902400)3.48984096
60signal transduction involved in mitotic G1 DNA damage checkpoint (GO:0072431)3.48984096
61protein localization to kinetochore (GO:0034501)3.48351794
62kinetochore assembly (GO:0051382)3.46430127
63regulation of cellular amino acid metabolic process (GO:0006521)3.44049473
64signal transduction involved in DNA damage checkpoint (GO:0072422)3.42759786
65signal transduction involved in DNA integrity checkpoint (GO:0072401)3.42759786
66DNA replication-dependent nucleosome organization (GO:0034723)3.42509021
67DNA replication-dependent nucleosome assembly (GO:0006335)3.42509021
68signal transduction involved in cell cycle checkpoint (GO:0072395)3.41872874
69positive regulation of ligase activity (GO:0051351)3.41134435
70mitochondrial respiratory chain complex assembly (GO:0033108)3.39284379
71spliceosomal snRNP assembly (GO:0000387)3.39008139
72protein localization to endoplasmic reticulum (GO:0070972)3.37761447
73* rRNA metabolic process (GO:0016072)3.37685953
74telomere maintenance via telomere lengthening (GO:0010833)3.37554544
75establishment of protein localization to endoplasmic reticulum (GO:0072599)3.36977210
76histone mRNA metabolic process (GO:0008334)3.35419479
77protein complex biogenesis (GO:0070271)3.34838001
78protein localization to mitochondrion (GO:0070585)3.28482439
79cellular protein complex disassembly (GO:0043624)3.26713590
80metaphase plate congression (GO:0051310)3.26623388
81DNA double-strand break processing (GO:0000729)3.25722754
82rRNA methylation (GO:0031167)3.24983016
83viral life cycle (GO:0019058)3.24534636
84pseudouridine synthesis (GO:0001522)3.24433991
85histone exchange (GO:0043486)3.24395115
86nuclear pore organization (GO:0006999)3.24352680
87establishment of protein localization to mitochondrion (GO:0072655)3.23844982
88IMP metabolic process (GO:0046040)3.23059960
89regulation of transcription involved in G1/S transition of mitotic cell cycle (GO:0000083)3.22887050
90membrane disassembly (GO:0030397)3.21062894
91nuclear envelope disassembly (GO:0051081)3.21062894
92regulation of ubiquitin-protein transferase activity (GO:0051438)3.20649397
93oxidative phosphorylation (GO:0006119)3.18798355
94RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394)3.18248500
95tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388)3.18248500
96rRNA modification (GO:0000154)3.17916916
97DNA catabolic process, exonucleolytic (GO:0000738)3.17111399
98regulation of spindle organization (GO:0090224)3.16166546
99protein localization to chromosome, centromeric region (GO:0071459)3.11900866
100regulation of ligase activity (GO:0051340)3.10191180
101attachment of spindle microtubules to kinetochore (GO:0008608)3.08761995
102termination of RNA polymerase II transcription (GO:0006369)3.08622940
103translation (GO:0006412)3.07903986
104maturation of 5.8S rRNA (GO:0000460)3.07311553
105nucleotide-excision repair, DNA gap filling (GO:0006297)3.07184013
106mitochondrial respiratory chain complex I assembly (GO:0032981)3.07162978
107NADH dehydrogenase complex assembly (GO:0010257)3.07162978
108mitochondrial respiratory chain complex I biogenesis (GO:0097031)3.07162978
109DNA ligation (GO:0006266)3.04662384
110establishment of viral latency (GO:0019043)3.03685833
111nuclear pore complex assembly (GO:0051292)3.02269745
112spliceosomal complex assembly (GO:0000245)2.99785568
113transcription-coupled nucleotide-excision repair (GO:0006283)2.99620087
114anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process (GO:02.98174159
115negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436)2.97257837
116nuclear-transcribed mRNA catabolic process (GO:0000956)2.96918363
117viral mRNA export from host cell nucleus (GO:0046784)2.96031058
118regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051439)2.94852529
119protein complex disassembly (GO:0043241)2.94405296
120establishment of chromosome localization (GO:0051303)2.94209133
121cellular component biogenesis (GO:0044085)2.93279553
122positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051437)2.90323887
123termination of RNA polymerase III transcription (GO:0006386)2.89202494
124transcription elongation from RNA polymerase III promoter (GO:0006385)2.89202494
125exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay 2.87661995
126deoxyribonucleoside monophosphate metabolic process (GO:0009162)2.82506744
127folic acid metabolic process (GO:0046655)2.82485328
128mRNA catabolic process (GO:0006402)2.82043219
129macromolecular complex disassembly (GO:0032984)2.81465236
130RNA splicing, via transesterification reactions (GO:0000375)2.79160880
131regulation of nuclear cell cycle DNA replication (GO:0033262)2.78764462
132RNA catabolic process (GO:0006401)2.77889000
133mRNA splicing, via spliceosome (GO:0000398)2.77263851
134RNA splicing, via transesterification reactions with bulged adenosine as nucleophile (GO:0000377)2.77263851
135chromatin assembly or disassembly (GO:0006333)2.77124448
136cell cycle G1/S phase transition (GO:0044843)2.76912214
137G1/S transition of mitotic cell cycle (GO:0000082)2.76912214
138negative regulation of mitotic metaphase/anaphase transition (GO:0045841)2.73449208
139negative regulation of sister chromatid segregation (GO:0033046)2.73449208
140negative regulation of mitotic sister chromatid separation (GO:2000816)2.73449208
141negative regulation of mitotic sister chromatid segregation (GO:0033048)2.73449208
142telomere maintenance (GO:0000723)2.72574762
143nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291)2.72404952
144negative regulation of chromosome segregation (GO:0051985)2.71609123
145regulation of double-strand break repair via homologous recombination (GO:0010569)2.71547497
146telomere organization (GO:0032200)2.71280042

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1E2F7_22180533_ChIP-Seq_HELA_Human7.19544151
2MYC_18555785_ChIP-Seq_MESCs_Mouse4.32430481
3EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse3.58187518
4E2F4_17652178_ChIP-ChIP_JURKAT_Human3.45297904
5FOXM1_23109430_ChIP-Seq_U2OS_Human3.36919482
6KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human3.33516141
7GABP_17652178_ChIP-ChIP_JURKAT_Human3.08900573
8EST1_17652178_ChIP-ChIP_JURKAT_Human3.08452880
9FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human2.95978924
10JARID1A_20064375_ChIP-Seq_MESCs_Mouse2.86906691
11MYC_19079543_ChIP-ChIP_MESCs_Mouse2.84536235
12ETS1_20019798_ChIP-Seq_JURKAT_Human2.81243497
13MYC_19030024_ChIP-ChIP_MESCs_Mouse2.80306752
14MYC_18358816_ChIP-ChIP_MESCs_Mouse2.77491302
15CREB1_15753290_ChIP-ChIP_HEK293T_Human2.70587869
16HCFC1_20581084_ChIP-Seq_MESCs_Mouse2.42467289
17NELFA_20434984_ChIP-Seq_ESCs_Mouse2.41741971
18* VDR_23849224_ChIP-Seq_CD4+_Human2.40070793
19* XRN2_22483619_ChIP-Seq_HELA_Human2.29682450
20CHD1_19587682_ChIP-ChIP_MESCs_Mouse2.27938516
21ELF1_17652178_ChIP-ChIP_JURKAT_Human2.18483265
22NOTCH1_17114293_ChIP-ChIP_T-ALL_Human2.10329192
23FOXP3_21729870_ChIP-Seq_TREG_Human2.07953659
24E2F1_18555785_ChIP-Seq_MESCs_Mouse2.07096119
25DCP1A_22483619_ChIP-Seq_HELA_Human2.05700021
26SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse2.02231322
27AR_21909140_ChIP-Seq_LNCAP_Human1.89236794
28E2F1_21310950_ChIP-Seq_MCF-7_Human1.88740777
29ELK1_19687146_ChIP-ChIP_HELA_Human1.86891073
30* HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human1.86866340
31MYBL2_22936984_ChIP-ChIP_MESCs_Mouse1.86291805
32GABP_19822575_ChIP-Seq_HepG2_Human1.85432272
33MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse1.85149003
34TTF2_22483619_ChIP-Seq_HELA_Human1.81277530
35PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse1.80285362
36TAL1_20887958_ChIP-Seq_HPC-7_Mouse1.79026747
37MYCN_18555785_ChIP-Seq_MESCs_Mouse1.78282819
38SOX9_22984422_ChIP-ChIP_TESTIS_Rat1.75186330
39HOXB4_20404135_ChIP-ChIP_EML_Mouse1.73434856
40* FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse1.73341520
41POU5F1_18555785_ChIP-Seq_MESCs_Mouse1.67854573
42NANOG_18555785_ChIP-Seq_MESCs_Mouse1.67173505
43E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse1.64331402
44THAP11_20581084_ChIP-Seq_MESCs_Mouse1.63913673
45CIITA_25753668_ChIP-Seq_RAJI_Human1.60973589
46EGR1_19374776_ChIP-ChIP_THP-1_Human1.56940599
47ZFX_18555785_ChIP-Seq_MESCs_Mouse1.53955852
48* YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.51497109
49* KDM5B_21448134_ChIP-Seq_MESCs_Mouse1.51285206
50SRF_21415370_ChIP-Seq_HL-1_Mouse1.48995625
51FLI1_20887958_ChIP-Seq_HPC-7_Mouse1.48014770
52SFPI1_20887958_ChIP-Seq_HPC-7_Mouse1.45925375
53ZFP42_18358816_ChIP-ChIP_MESCs_Mouse1.45213360
54MYC_22102868_ChIP-Seq_BL_Human1.44697270
55CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human1.44454025
56ERG_20887958_ChIP-Seq_HPC-7_Mouse1.44270676
57* YY1_21170310_ChIP-Seq_MESCs_Mouse1.43048270
58* KDM5A_27292631_Chip-Seq_BREAST_Human1.38054000
59ASXL1_24218140_ChIP-Seq_BMDM_Mouse1.37055402
60NOTCH1_21737748_ChIP-Seq_TLL_Human1.35249606
61SPI1_22096565_ChIP-ChIP_GC-B_Mouse1.29470486
62MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.25662309
63PADI4_21655091_ChIP-ChIP_MCF-7_Human1.23079180
64STAT3_1855785_ChIP-Seq_MESCs_Mouse1.21273253
65RBPJ_22232070_ChIP-Seq_NCS_Mouse1.18703783
66FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse1.17303998
67POU5F1_18358816_ChIP-ChIP_MESCs_Mouse1.16224454
68EWS_26573619_Chip-Seq_HEK293_Human1.14677052
69PDX1_19855005_ChIP-ChIP_MIN6_Mouse1.13753469
70TFEB_21752829_ChIP-Seq_HELA_Human1.13328195
71POU5F1_18700969_ChIP-ChIP_MESCs_Mouse1.12180109
72CCND1_20090754_ChIP-ChIP_RETINA_Mouse1.10734778
73IRF8_22096565_ChIP-ChIP_GC-B_Mouse1.09627067
74SPI1_23547873_ChIP-Seq_NB4_Human1.09029019
75E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human1.08618436
76KLF4_18555785_ChIP-Seq_MESCs_Mouse1.07387681
77SMAD1_18555785_ChIP-Seq_MESCs_Mouse1.06657416
78TP63_19390658_ChIP-ChIP_HaCaT_Human1.06220807
79GFI1B_20887958_ChIP-Seq_HPC-7_Mouse1.04323576
80CNOT3_19339689_ChIP-ChIP_MESCs_Mouse1.04216767
81MYC_18940864_ChIP-ChIP_HL60_Human1.03997881
82SOX2_18555785_ChIP-Seq_MESCs_Mouse1.00073057
83* ASH2L_23239880_ChIP-Seq_MESCs_Mouse0.99431716
84CEBPB_23403033_ChIP-Seq_LIVER_Mouse0.99137222
85FUS_26573619_Chip-Seq_HEK293_Human0.98036203
86DACH1_20351289_ChIP-Seq_MDA-MB-231_Human0.97883449
87BCL3_23251550_ChIP-Seq_MUSCLE_Mouse0.97369731
88KLF4_19030024_ChIP-ChIP_MESCs_Mouse0.95922678
89ZNF274_21170338_ChIP-Seq_K562_Hela0.95546872
90ELK1_22589737_ChIP-Seq_MCF10A_Human0.94206703
91PRDM5_23873026_ChIP-Seq_MEFs_Mouse0.94173326
92SALL1_21062744_ChIP-ChIP_HESCs_Human0.93974091
93SOX17_20123909_ChIP-Seq_XEN_Mouse0.92488041
94VDR_21846776_ChIP-Seq_THP-1_Human0.90915034
95HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse0.90235937
96CUX1_19635798_ChIP-ChIP_MULTIPLE_HUMAN_CANCER_TYPES_Human0.86832388
97CEBPA_23403033_ChIP-Seq_LIVER_Mouse0.85657037
98CREM_20920259_ChIP-Seq_GC1-SPG_Mouse0.85121773
99CEBPB_24764292_ChIP-Seq_MC3T3_Mouse0.84522155
100NANOG_16153702_ChIP-ChIP_HESCs_Human0.84450137
101HSF1_23293686_ChIP-Seq_STHDH_STRIATAL_Mouse0.82220893
102TCF3_18692474_ChIP-Seq_MEFs_Mouse0.79855554
103CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat0.78850296
104KLF4_18358816_ChIP-ChIP_MESCs_Mouse0.78300786
105POU5F1_16153702_ChIP-ChIP_HESCs_Human0.77897834
106TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse0.75840997
107ELF5_23300383_ChIP-Seq_T47D_Human0.74614467
108HNF4A_19761587_ChIP-ChIP_CACO-2_Human0.74529481
109CREB1_20920259_ChIP-Seq_GC1-SPG_Mouse0.73967232
110SOX2_16153702_ChIP-ChIP_HESCs_Human0.73371754
111FLI1_27457419_Chip-Seq_LIVER_Mouse0.69746188
112IRF1_19129219_ChIP-ChIP_H3396_Human0.66670667
113SOX2_19030024_ChIP-ChIP_MESCs_Mouse0.66036309
114RCOR1_19997604_ChIP-ChIP_NEURONS_Mouse0.65696607
115FLI1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.64393158
116TP53_22573176_ChIP-Seq_HFKS_Human0.64345357

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0003693_abnormal_embryo_hatching5.39487019
2MP0010094_abnormal_chromosome_stability4.27734114
3MP0004957_abnormal_blastocyst_morpholog4.04938909
4MP0003111_abnormal_nucleus_morphology3.91527983
5MP0003077_abnormal_cell_cycle3.67323317
6MP0008057_abnormal_DNA_replication3.45440902
7MP0008058_abnormal_DNA_repair3.22914646
8MP0008007_abnormal_cellular_replicative2.91484802
9MP0002396_abnormal_hematopoietic_system2.50524597
10MP0008932_abnormal_embryonic_tissue2.38911165
11MP0006072_abnormal_retinal_apoptosis2.03645728
12MP0001730_embryonic_growth_arrest1.97768157
13MP0006035_abnormal_mitochondrial_morpho1.96049703
14MP0000350_abnormal_cell_proliferation1.92502211
15MP0003786_premature_aging1.90436768
16MP0003806_abnormal_nucleotide_metabolis1.80083368
17MP0010352_gastrointestinal_tract_polyps1.79327814
18MP0003718_maternal_effect1.73998901
19MP0003763_abnormal_thymus_physiology1.73959646
20MP0000490_abnormal_crypts_of1.72429813
21MP0009333_abnormal_splenocyte_physiolog1.67478768
22MP0010307_abnormal_tumor_latency1.67389043
23MP0000372_irregular_coat_pigmentation1.66371581
24MP0002163_abnormal_gland_morphology1.59360765
25MP0005084_abnormal_gallbladder_morpholo1.54798685
26MP0003123_paternal_imprinting1.54147295
27MP0004808_abnormal_hematopoietic_stem1.51416039
28MP0005397_hematopoietic_system_phenotyp1.51262832
29MP0001545_abnormal_hematopoietic_system1.51262832
30MP0001529_abnormal_vocalization1.48966398
31MP0001697_abnormal_embryo_size1.46660352
32MP0002019_abnormal_tumor_incidence1.44407302
33MP0001672_abnormal_embryogenesis/_devel1.44273235
34MP0005380_embryogenesis_phenotype1.44273235
35MP0006292_abnormal_olfactory_placode1.39028128
36MP0000313_abnormal_cell_death1.38851324
37MP0002398_abnormal_bone_marrow1.37876213
38MP0003186_abnormal_redox_activity1.37069845
39MP0002080_prenatal_lethality1.36595001
40MP0008877_abnormal_DNA_methylation1.35583796
41MP0008995_early_reproductive_senescence1.31039164
42MP0001835_abnormal_antigen_presentation1.29690471
43MP0003984_embryonic_growth_retardation1.29619596
44MP0000703_abnormal_thymus_morphology1.28338109
45MP0002722_abnormal_immune_system1.27335721
46MP0000689_abnormal_spleen_morphology1.27019581
47MP0002234_abnormal_pharynx_morphology1.26041032
48MP0002088_abnormal_embryonic_growth/wei1.25762151
49MP0005671_abnormal_response_to1.23031990
50MP0001853_heart_inflammation1.20218962
51MP0002086_abnormal_extraembryonic_tissu1.16023929
52MP0002085_abnormal_embryonic_tissue1.15657547
53MP0001293_anophthalmia1.15465665
54MP0002102_abnormal_ear_morphology1.12368304
55MP0002429_abnormal_blood_cell1.10335028
56MP0002132_abnormal_respiratory_system1.08787616
57MP0002084_abnormal_developmental_patter1.07139971
58MP0003941_abnormal_skin_development1.06688734
59MP0001800_abnormal_humoral_immune1.06673322
60MP0001727_abnormal_embryo_implantation1.05845643
61MP0003567_abnormal_fetal_cardiomyocyte1.03990818
62MP0000858_altered_metastatic_potential1.03889861
63MP0000716_abnormal_immune_system1.03703127
64MP0003937_abnormal_limbs/digits/tail_de1.02778705
65MP0003890_abnormal_embryonic-extraembry1.00781722
66MP0000685_abnormal_immune_system1.00222644
67MP0002210_abnormal_sex_determination0.99702961
68MP0004197_abnormal_fetal_growth/weight/0.99085405
69MP0009785_altered_susceptibility_to0.96276970
70MP0002166_altered_tumor_susceptibility0.95412331
71MP0009379_abnormal_foot_pigmentation0.95312240
72MP0003011_delayed_dark_adaptation0.93807866
73MP0005075_abnormal_melanosome_morpholog0.93124912
74MP0002420_abnormal_adaptive_immunity0.91781940
75MP0002452_abnormal_antigen_presenting0.91186237
76MP0001819_abnormal_immune_cell0.90612615
77MP0000358_abnormal_cell_content/0.90287585
78MP0001881_abnormal_mammary_gland0.88943238
79MP0003436_decreased_susceptibility_to0.88678477
80MP0002405_respiratory_system_inflammati0.88647049
81MP0003121_genomic_imprinting0.87974636
82MP0005379_endocrine/exocrine_gland_phen0.87176814
83MP0002723_abnormal_immune_serum0.86344338
84MP0006054_spinal_hemorrhage0.86280041
85MP0001145_abnormal_male_reproductive0.86071110
86MP0005253_abnormal_eye_physiology0.84229492
87MP0008873_increased_physiological_sensi0.82923785
88MP0002006_tumorigenesis0.82290429
89MP0002095_abnormal_skin_pigmentation0.81642105
90MP0001119_abnormal_female_reproductive0.81359217
91MP0005076_abnormal_cell_differentiation0.80982728
92MP0006036_abnormal_mitochondrial_physio0.79013749
93MP0004147_increased_porphyrin_level0.77982748
94MP0002938_white_spotting0.77813997
95MP0005389_reproductive_system_phenotype0.77710480
96MP0001286_abnormal_eye_development0.77498919
97MP0002837_dystrophic_cardiac_calcinosis0.77361300
98MP0001188_hyperpigmentation0.76393413
99MP0005025_abnormal_response_to0.76371515
100MP0008789_abnormal_olfactory_epithelium0.76321437
101MP0000653_abnormal_sex_gland0.75880034
102MP0010155_abnormal_intestine_physiology0.75212368
103MP0002160_abnormal_reproductive_system0.74814713
104MP0001919_abnormal_reproductive_system0.74809053
105MP0005000_abnormal_immune_tolerance0.74139921
106MP0004215_abnormal_myocardial_fiber0.73636177
107MP0005408_hypopigmentation0.72470005
108MP0002277_abnormal_respiratory_mucosa0.72126852
109MP0001929_abnormal_gametogenesis0.71703727
110MP0005023_abnormal_wound_healing0.71687174
111MP0009697_abnormal_copulation0.70285632
112MP0005384_cellular_phenotype0.69806741
113MP0000465_gastrointestinal_hemorrhage0.68551807
114MP0003315_abnormal_perineum_morphology0.67606286
115MP0001915_intracranial_hemorrhage0.67335563
116MP0005501_abnormal_skin_physiology0.66559541
117MP0005367_renal/urinary_system_phenotyp0.65659305
118MP0000516_abnormal_urinary_system0.65659305
119MP0005174_abnormal_tail_pigmentation0.65377888
120MP0001764_abnormal_homeostasis0.65375942
121MP0003698_abnormal_male_reproductive0.65172101
122MP0005266_abnormal_metabolism0.65038906
123MP0005621_abnormal_cell_physiology0.64996835
124MP0005395_other_phenotype0.62312993
125MP0003221_abnormal_cardiomyocyte_apopto0.61523908
126MP0002148_abnormal_hypersensitivity_rea0.61105199
127MP0005330_cardiomyopathy0.61001095
128MP0002111_abnormal_tail_morphology0.60791417
129MP0000598_abnormal_liver_morphology0.60319683
130MP0001873_stomach_inflammation0.60237531
131MP0000477_abnormal_intestine_morphology0.59822510
132MP0001845_abnormal_inflammatory_respons0.59102192
133MP0009053_abnormal_anal_canal0.58973082
134MP0005391_vision/eye_phenotype0.58803065
135MP0002090_abnormal_vision0.58211002
136MP0000627_abnormal_mammary_gland0.56276016
137MP0002638_abnormal_pupillary_reflex0.55643211
138MP0000631_abnormal_neuroendocrine_gland0.55377310
139MP0009250_abnormal_appendicular_skeleto0.54780935
140MP0000647_abnormal_sebaceous_gland0.54098053

Predicted human phenotypes

RankGene SetZ-score
1Birth length less than 3rd percentile (HP:0003561)4.95024845
2Acute necrotizing encephalopathy (HP:0006965)4.84908518
3Abnormality of cells of the erythroid lineage (HP:0012130)4.84815445
4Abnormal number of erythroid precursors (HP:0012131)4.73438390
5Reticulocytopenia (HP:0001896)4.70708444
6Abnormal mitochondria in muscle tissue (HP:0008316)4.47763284
7Increased hepatocellular lipid droplets (HP:0006565)4.37978016
8Increased CSF lactate (HP:0002490)4.26918657
9Mitochondrial inheritance (HP:0001427)4.26103396
10Acute encephalopathy (HP:0006846)4.23248516
11Lipid accumulation in hepatocytes (HP:0006561)4.04378478
12Progressive macrocephaly (HP:0004481)3.97160830
13Hepatocellular necrosis (HP:0001404)3.94542116
14Aplastic anemia (HP:0001915)3.92103757
15Breast hypoplasia (HP:0003187)3.77632322
16Hepatic necrosis (HP:0002605)3.73157020
17Oral leukoplakia (HP:0002745)3.70727465
183-Methylglutaconic aciduria (HP:0003535)3.59247603
19Cerebral edema (HP:0002181)3.41650001
20Macrocytic anemia (HP:0001972)3.32774219
21Chromsome breakage (HP:0040012)3.31247656
22Pallor (HP:0000980)3.26139675
23Degeneration of anterior horn cells (HP:0002398)3.23108232
24Abnormality of the anterior horn cell (HP:0006802)3.23108232
25Increased intramyocellular lipid droplets (HP:0012240)3.18934326
26Carpal bone hypoplasia (HP:0001498)3.15084885
27Renal Fanconi syndrome (HP:0001994)3.01496391
28Patellar aplasia (HP:0006443)3.01393877
29Rough bone trabeculation (HP:0100670)2.99614026
30Lactic acidosis (HP:0003128)2.97053525
31Microretrognathia (HP:0000308)2.93327994
32Selective tooth agenesis (HP:0001592)2.92730662
33Colon cancer (HP:0003003)2.88723907
34Chromosomal breakage induced by crosslinking agents (HP:0003221)2.88427295
35Abnormality of chromosome stability (HP:0003220)2.86990770
36Thrombocytosis (HP:0001894)2.83299790
37Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688)2.81688745
38Abnormality of the preputium (HP:0100587)2.79788807
39Aplasia/Hypoplasia of the patella (HP:0006498)2.79374350
40Increased serum pyruvate (HP:0003542)2.72195814
41Exercise intolerance (HP:0003546)2.71678502
42Myelodysplasia (HP:0002863)2.70958097
43Meckel diverticulum (HP:0002245)2.69996985
44Exertional dyspnea (HP:0002875)2.68720190
45Increased muscle lipid content (HP:0009058)2.62072671
46Respiratory difficulties (HP:0002880)2.61916476
47Muscle abnormality related to mitochondrial dysfunction (HP:0003800)2.61791555
48Premature ovarian failure (HP:0008209)2.60106037
49IgM deficiency (HP:0002850)2.58583961
50Abnormality of the ileum (HP:0001549)2.57076117
51Absent thumb (HP:0009777)2.52891406
52Medulloblastoma (HP:0002885)2.50999490
53Respiratory failure (HP:0002878)2.50171267
54Premature graying of hair (HP:0002216)2.50089148
55Leukodystrophy (HP:0002415)2.46723666
56Bone marrow hypocellularity (HP:0005528)2.42655784
57Aplasia/Hypoplasia of the uvula (HP:0010293)2.41233384
58Congenital, generalized hypertrichosis (HP:0004540)2.40662043
59Abnormality of methionine metabolism (HP:0010901)2.39646036
60Abnormality of alanine metabolism (HP:0010916)2.33155410
61Hyperalaninemia (HP:0003348)2.33155410
62Abnormality of pyruvate family amino acid metabolism (HP:0010915)2.33155410
63Cellular immunodeficiency (HP:0005374)2.32558015
64Volvulus (HP:0002580)2.29247408
65Abnormality of glycolysis (HP:0004366)2.28596317
66Agnosia (HP:0010524)2.28513025
67Impulsivity (HP:0100710)2.26278237
68Absent radius (HP:0003974)2.25835278
69Type I transferrin isoform profile (HP:0003642)2.25480654
70Trismus (HP:0000211)2.24089481
71Cerebral hypomyelination (HP:0006808)2.23987781
72Multiple enchondromatosis (HP:0005701)2.23460076
73Neoplasm of the pancreas (HP:0002894)2.22942808
74Pancytopenia (HP:0001876)2.20870551
75Lymphoma (HP:0002665)2.20754149
76Duodenal stenosis (HP:0100867)2.19418182
77Small intestinal stenosis (HP:0012848)2.19418182
78Amaurosis fugax (HP:0100576)2.18550867
79Decreased activity of mitochondrial respiratory chain (HP:0008972)2.17504201
80Abnormal activity of mitochondrial respiratory chain (HP:0011922)2.17504201
81Abnormal trabecular bone morphology (HP:0100671)2.17446308
82Aplasia/hypoplasia of the uterus (HP:0008684)2.14057185
83Methylmalonic acidemia (HP:0002912)2.13946237
84Amniotic constriction ring (HP:0009775)2.13536151
85Abnormality of placental membranes (HP:0011409)2.13536151
86Lethargy (HP:0001254)2.08129632
8711 pairs of ribs (HP:0000878)2.07931384
88Abnormal isoelectric focusing of serum transferrin (HP:0003160)2.07881353
89Abnormal protein N-linked glycosylation (HP:0012347)2.07881353
90Abnormal protein glycosylation (HP:0012346)2.07881353
91Abnormal glycosylation (HP:0012345)2.07881353
92Cleft eyelid (HP:0000625)2.07638175
93Abnormality of pyrimidine metabolism (HP:0004353)2.07396399
94Optic disc pallor (HP:0000543)2.06626082
95B lymphocytopenia (HP:0010976)2.04743431
96Supernumerary spleens (HP:0009799)2.04038521
97Aplasia involving forearm bones (HP:0009822)2.03634994
98Absent forearm bone (HP:0003953)2.03634994
99Abnormality of the heme biosynthetic pathway (HP:0010472)2.03553410
100Abnormal number of incisors (HP:0011064)2.03331366
101Rhabdomyosarcoma (HP:0002859)2.02912664
102Generalized aminoaciduria (HP:0002909)2.02844373
103Short middle phalanx of the 5th finger (HP:0004220)2.02593094
104Aplasia/Hypoplasia of the sacrum (HP:0008517)2.02168824
105Sloping forehead (HP:0000340)2.02011302
106Secondary amenorrhea (HP:0000869)1.99655676
107Muscle fiber atrophy (HP:0100295)1.97275084
108Atresia of the external auditory canal (HP:0000413)1.94822753
109Petechiae (HP:0000967)1.94298096
110Abnormality of reticulocytes (HP:0004312)1.91639358
111Triphalangeal thumb (HP:0001199)1.91459063
112Optic nerve coloboma (HP:0000588)1.91190607
113CNS demyelination (HP:0007305)1.91160199
114Aplasia/Hypoplasia involving the carpal bones (HP:0006502)1.90929230
115IgG deficiency (HP:0004315)1.89283334
116Microvesicular hepatic steatosis (HP:0001414)1.88889995
117Abnormality of the duodenum (HP:0002246)1.88168548
118Horseshoe kidney (HP:0000085)1.87564251
119Abnormality of serum amino acid levels (HP:0003112)1.85777615
120Abnormality of renal resorption (HP:0011038)1.85519101
121Abnormality of aspartate family amino acid metabolism (HP:0010899)1.85085311
122Glycosuria (HP:0003076)1.84960170
123Abnormality of urine glucose concentration (HP:0011016)1.84960170
124Methylmalonic aciduria (HP:0012120)1.84504941
125Stenosis of the external auditory canal (HP:0000402)1.83544027
126Increased serum lactate (HP:0002151)1.82857375
127Type 2 muscle fiber atrophy (HP:0003554)1.82732669
128Granulocytopenia (HP:0001913)1.82307771
129Sparse eyelashes (HP:0000653)1.81983511
130Abnormal lung lobation (HP:0002101)1.81545883
131Abnormality of T cells (HP:0002843)1.79819088
132Combined immunodeficiency (HP:0005387)1.79289044
133Abnormality of the labia minora (HP:0012880)1.78377356
134Reduced antithrombin III activity (HP:0001976)1.78248731
135Facial hemangioma (HP:0000329)1.77633021
136Severe combined immunodeficiency (HP:0004430)1.77373445
137Abnormal spermatogenesis (HP:0008669)1.76966877
138Aplasia/Hypoplasia of the middle phalanx of the 5th finger (HP:0009161)1.76831296
139Entropion (HP:0000621)1.76798066
140Progressive muscle weakness (HP:0003323)1.75174872
141Megaloblastic anemia (HP:0001889)1.74770991
142Clubbing of toes (HP:0100760)1.74547711
143X-linked dominant inheritance (HP:0001423)1.74467195
144Tracheoesophageal fistula (HP:0002575)1.74316398
145Pancreatic cysts (HP:0001737)1.73774732
146Abnormality of T cell physiology (HP:0011840)1.72335212
147Abnormality of the pons (HP:0007361)1.72329783
148Acute myeloid leukemia (HP:0004808)1.72298738
149Proximal placement of thumb (HP:0009623)1.72251282
150Basal cell carcinoma (HP:0002671)1.72045667
151Renal cortical cysts (HP:0000803)1.71850393
152Prominent nose (HP:0000448)1.71575596
153Aplasia/Hypoplasia of the thymus (HP:0010515)1.70582601
154Ependymoma (HP:0002888)1.69267519
155Hypoplasia of the radius (HP:0002984)1.67419492
156Leukopenia (HP:0001882)1.65256424
157Poikiloderma (HP:0001029)1.63987908
158Slender long bone (HP:0003100)1.63959939

Predicted kinase interactions (KEA)

RankGene SetZ-score
1BUB14.30950017
2WEE14.10040411
3CDC73.32759302
4EIF2AK13.32572328
5VRK22.91797077
6NME22.72275430
7STK162.69647537
8SRPK12.64233233
9ACVR1B2.58730334
10TRIM282.46676571
11NEK22.37550835
12EIF2AK32.33775499
13BRSK22.31101862
14PLK42.27609154
15NUAK12.20974202
16DYRK31.97333888
17VRK11.92338111
18RPS6KA41.90992231
19RPS6KB21.88228816
20MAP3K121.87482814
21TLK11.86998244
22TSSK61.82895135
23TTK1.76813650
24TESK21.75156561
25PLK11.70957613
26MKNK11.63153572
27CDK71.60858852
28AURKB1.59554767
29PDK21.57455812
30PNCK1.56079219
31STK101.50640297
32ATR1.48196408
33NEK11.47871038
34PIM21.47258714
35ZAK1.37965694
36KDR1.31263200
37MKNK21.29739345
38EPHA21.29330535
39PASK1.27453418
40TGFBR11.24941405
41PLK31.21113709
42MAP3K81.18698747
43BMPR1B1.14378659
44MAP4K11.12801922
45CDK41.12628959
46CHEK21.11048392
47STK41.09243106
48WNK31.08850326
49PIM11.08200784
50ERBB31.07602093
51SCYL21.07572011
52CDK121.04914203
53AURKA1.04337332
54BRSK11.03523040
55TAF11.03305305
56BCR1.01904600
57FLT30.94671511
58IRAK30.94161415
59EIF2AK20.91102328
60MAP4K20.90916646
61CHEK10.90217272
62CCNB10.89313111
63PAK40.87364894
64TEC0.82335926
65PBK0.81993719
66RPS6KA50.81830490
67TXK0.80440188
68MAPKAPK30.79409286
69EEF2K0.76016306
70LRRK20.73988671
71ATM0.72518898
72BTK0.71286646
73ZAP700.71124751
74CDK30.68347023
75NEK90.68175448
76CSNK2A20.67100816
77CSNK2A10.65029418
78TYK20.64344262
79CDK80.64044529
80CDK20.64007145
81TESK10.61195902
82MST40.60374876
83CLK10.60344062
84MAP3K100.59661773
85CDK60.59146301
86IRAK40.57917270
87BLK0.57694723
88MELK0.55112550
89BRAF0.54968862
90MAP2K30.53826292
91BCKDK0.53279777
92SIK30.52788024
93PLK20.52768426
94IKBKB0.52190614
95CSNK1G10.50987381
96JAK30.50806237
97KIT0.48905866
98CSNK1E0.46835685
99PAK10.45826217
100DAPK10.43927529
101CDK90.43773839
102TNIK0.43615610
103CDK190.43291257
104CDK10.42645423
105CSNK1G30.39808564
106NLK0.39418377
107BRD40.39104265
108CHUK0.37665427
109STK30.36240384
110PRKCI0.35471268
111GRK10.35349375
112STK390.34441120
113DYRK20.33362484
114MAP3K40.32567881
115AKT30.31463191
116LYN0.31289213
117ADRBK20.31134706
118MAP3K30.30797566
119NME10.30586656
120ITK0.30539970
121MAP3K110.30109907
122ILK0.27793520
123STK38L0.27755220
124ERBB40.27321457
125ABL20.27200869
126ALK0.25099796
127MARK30.24597890
128FGFR10.24401654
129TGFBR20.23913561
130MYLK0.22787332
131YES10.22246678
132MAP3K50.22112976

Predicted pathways (KEGG)

RankGene SetZ-score
1DNA replication_Homo sapiens_hsa030304.43296240
2Ribosome_Homo sapiens_hsa030103.94459081
3Mismatch repair_Homo sapiens_hsa034303.74413570
4Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030083.61390779
5Proteasome_Homo sapiens_hsa030503.30098118
6RNA polymerase_Homo sapiens_hsa030203.29996762
7Oxidative phosphorylation_Homo sapiens_hsa001903.27322848
8Spliceosome_Homo sapiens_hsa030403.22227155
9RNA transport_Homo sapiens_hsa030132.88444870
10Base excision repair_Homo sapiens_hsa034102.74173705
11Homologous recombination_Homo sapiens_hsa034402.65810685
12Nucleotide excision repair_Homo sapiens_hsa034202.63154450
13One carbon pool by folate_Homo sapiens_hsa006702.57771238
14Pyrimidine metabolism_Homo sapiens_hsa002402.50674646
15Cell cycle_Homo sapiens_hsa041102.36321966
16Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009702.22217989
17Fanconi anemia pathway_Homo sapiens_hsa034601.95583852
18RNA degradation_Homo sapiens_hsa030181.88787316
19Non-homologous end-joining_Homo sapiens_hsa034501.88271201
20Basal transcription factors_Homo sapiens_hsa030221.85140143
21Alzheimers disease_Homo sapiens_hsa050101.75664415
22p53 signaling pathway_Homo sapiens_hsa041151.58572811
23Cytosolic DNA-sensing pathway_Homo sapiens_hsa046231.49277314
24Terpenoid backbone biosynthesis_Homo sapiens_hsa009001.42718195
25Systemic lupus erythematosus_Homo sapiens_hsa053221.41865780
26Folate biosynthesis_Homo sapiens_hsa007901.39073451
27mRNA surveillance pathway_Homo sapiens_hsa030151.38476617
28Protein export_Homo sapiens_hsa030601.33775892
29Purine metabolism_Homo sapiens_hsa002301.30705508
30Antigen processing and presentation_Homo sapiens_hsa046121.21781011
31Epstein-Barr virus infection_Homo sapiens_hsa051691.21634307
32Pyruvate metabolism_Homo sapiens_hsa006201.18047271
33Herpes simplex infection_Homo sapiens_hsa051681.15568415
34Propanoate metabolism_Homo sapiens_hsa006401.15391349
35Synthesis and degradation of ketone bodies_Homo sapiens_hsa000721.10427495
36Selenocompound metabolism_Homo sapiens_hsa004501.06466663
37Drug metabolism - other enzymes_Homo sapiens_hsa009830.99013438
38Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.98147103
39Primary immunodeficiency_Homo sapiens_hsa053400.96400622
40Sulfur relay system_Homo sapiens_hsa041220.94769447
41Pentose phosphate pathway_Homo sapiens_hsa000300.94639436
42Steroid biosynthesis_Homo sapiens_hsa001000.92897809
43Cysteine and methionine metabolism_Homo sapiens_hsa002700.92538171
44Viral carcinogenesis_Homo sapiens_hsa052030.90133151
45Fatty acid elongation_Homo sapiens_hsa000620.86193640
46Cardiac muscle contraction_Homo sapiens_hsa042600.85136067
47Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.84373286
48Cyanoamino acid metabolism_Homo sapiens_hsa004600.82767136
49Biosynthesis of amino acids_Homo sapiens_hsa012300.80235520
50Vitamin B6 metabolism_Homo sapiens_hsa007500.79918390
51Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.72741133
52Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.71941090
53Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.71342965
54Valine, leucine and isoleucine degradation_Homo sapiens_hsa002800.71213821
55Legionellosis_Homo sapiens_hsa051340.70905062
56NF-kappa B signaling pathway_Homo sapiens_hsa040640.64593534
57Measles_Homo sapiens_hsa051620.64481478
58Sulfur metabolism_Homo sapiens_hsa009200.64433309
59HTLV-I infection_Homo sapiens_hsa051660.64188508
60Regulation of autophagy_Homo sapiens_hsa041400.57526667
61Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001300.56050106
62Glutathione metabolism_Homo sapiens_hsa004800.55105063
63Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.53196804
64Apoptosis_Homo sapiens_hsa042100.51024015
65Intestinal immune network for IgA production_Homo sapiens_hsa046720.51017137
66Oocyte meiosis_Homo sapiens_hsa041140.50318657
67Transcriptional misregulation in cancer_Homo sapiens_hsa052020.48626747
68Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.48561380
69Hematopoietic cell lineage_Homo sapiens_hsa046400.48451942
70Allograft rejection_Homo sapiens_hsa053300.47585183
71Small cell lung cancer_Homo sapiens_hsa052220.46578551
72Huntingtons disease_Homo sapiens_hsa050160.46059688
73Thyroid cancer_Homo sapiens_hsa052160.44546886
74Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.43579261
75Carbon metabolism_Homo sapiens_hsa012000.42139426
76Peroxisome_Homo sapiens_hsa041460.41302349
77RIG-I-like receptor signaling pathway_Homo sapiens_hsa046220.39279521
78Butanoate metabolism_Homo sapiens_hsa006500.39159554
79Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.38694761
80Influenza A_Homo sapiens_hsa051640.36399519
81Hepatitis B_Homo sapiens_hsa051610.36159921
82Asthma_Homo sapiens_hsa053100.36000458
83Pentose and glucuronate interconversions_Homo sapiens_hsa000400.35052045
84N-Glycan biosynthesis_Homo sapiens_hsa005100.34890329
85NOD-like receptor signaling pathway_Homo sapiens_hsa046210.32348438
86Graft-versus-host disease_Homo sapiens_hsa053320.31423467
87Shigellosis_Homo sapiens_hsa051310.30646569
88Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006300.30012177
89Parkinsons disease_Homo sapiens_hsa050120.29836367
90Butirosin and neomycin biosynthesis_Homo sapiens_hsa005240.28921070
91Renin-angiotensin system_Homo sapiens_hsa046140.28874167
92Metabolic pathways_Homo sapiens_hsa011000.28724105
93Alcoholism_Homo sapiens_hsa050340.28661323
94MicroRNAs in cancer_Homo sapiens_hsa052060.28600602
95Inflammatory bowel disease (IBD)_Homo sapiens_hsa053210.27614598
96Jak-STAT signaling pathway_Homo sapiens_hsa046300.25631592
972-Oxocarboxylic acid metabolism_Homo sapiens_hsa012100.25550180
98Fructose and mannose metabolism_Homo sapiens_hsa000510.25304726
99Fatty acid degradation_Homo sapiens_hsa000710.25007517
100Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.23844961
101SNARE interactions in vesicular transport_Homo sapiens_hsa041300.23672494
102Maturity onset diabetes of the young_Homo sapiens_hsa049500.23161520
103Leishmaniasis_Homo sapiens_hsa051400.22871202
104Caffeine metabolism_Homo sapiens_hsa002320.22571749
105Fatty acid metabolism_Homo sapiens_hsa012120.22113888
106Acute myeloid leukemia_Homo sapiens_hsa052210.21496245
107Collecting duct acid secretion_Homo sapiens_hsa049660.21491343
108Citrate cycle (TCA cycle)_Homo sapiens_hsa000200.21212432
109Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.20803356
110Galactose metabolism_Homo sapiens_hsa000520.18658920
111Colorectal cancer_Homo sapiens_hsa052100.18426928
112TGF-beta signaling pathway_Homo sapiens_hsa043500.17073113
113Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049320.16983768
114Tryptophan metabolism_Homo sapiens_hsa003800.16948804
115Viral myocarditis_Homo sapiens_hsa054160.15424038
116Vitamin digestion and absorption_Homo sapiens_hsa049770.15414318
117Type I diabetes mellitus_Homo sapiens_hsa049400.15121069
118Other glycan degradation_Homo sapiens_hsa005110.14646664
119Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.13898599
120Chemical carcinogenesis_Homo sapiens_hsa052040.13571845
121T cell receptor signaling pathway_Homo sapiens_hsa046600.13539803
122HIF-1 signaling pathway_Homo sapiens_hsa040660.13241341
123Cytokine-cytokine receptor interaction_Homo sapiens_hsa040600.12751718
124beta-Alanine metabolism_Homo sapiens_hsa004100.12715790
125Drug metabolism - cytochrome P450_Homo sapiens_hsa009820.11439148
126Retinol metabolism_Homo sapiens_hsa008300.07890663
127Arginine and proline metabolism_Homo sapiens_hsa003300.07622025
128Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.05718239
129Phototransduction_Homo sapiens_hsa047440.05457139

Most similar genes based on co-expression Upload to Enrichr

Tissue Expression Export image »

Cell Line Expression Export image »