RP9P

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1mitochondrial electron transport, NADH to ubiquinone (GO:0006120)4.01622290
2seminiferous tubule development (GO:0072520)3.96195418
3translational termination (GO:0006415)3.91480978
4substrate-independent telencephalic tangential interneuron migration (GO:0021843)3.87533468
5substrate-independent telencephalic tangential migration (GO:0021826)3.87533468
6viral transcription (GO:0019083)3.85406565
7detection of mechanical stimulus involved in sensory perception of sound (GO:0050910)3.70693413
8cornea development in camera-type eye (GO:0061303)3.65178466
9positive regulation of inositol phosphate biosynthetic process (GO:0060732)3.65019017
10ATP synthesis coupled proton transport (GO:0015986)3.58378382
11energy coupled proton transport, down electrochemical gradient (GO:0015985)3.58378382
12ribosomal small subunit assembly (GO:0000028)3.57713683
13mitochondrial ATP synthesis coupled proton transport (GO:0042776)3.57361749
14auditory behavior (GO:0031223)3.54557386
15behavioral response to nicotine (GO:0035095)3.50500854
16nonmotile primary cilium assembly (GO:0035058)3.47863774
17cotranslational protein targeting to membrane (GO:0006613)3.38990492
18epithelial cilium movement (GO:0003351)3.35594917
19SRP-dependent cotranslational protein targeting to membrane (GO:0006614)3.34738690
20protein targeting to ER (GO:0045047)3.32733083
21positive regulation of gastrulation (GO:2000543)3.27718825
22neuron fate determination (GO:0048664)3.22037594
23establishment of protein localization to endoplasmic reticulum (GO:0072599)3.20730219
24protein complex biogenesis (GO:0070271)3.20471978
25intraciliary transport (GO:0042073)3.19411556
26somite development (GO:0061053)3.18931902
27cell proliferation in forebrain (GO:0021846)3.18684338
28mitochondrial respiratory chain complex I biogenesis (GO:0097031)3.17392443
29mitochondrial respiratory chain complex I assembly (GO:0032981)3.17392443
30NADH dehydrogenase complex assembly (GO:0010257)3.17392443
31ribosomal small subunit biogenesis (GO:0042274)3.13206722
32protein localization to endoplasmic reticulum (GO:0070972)3.11816478
33respiratory electron transport chain (GO:0022904)3.10256657
34electron transport chain (GO:0022900)3.09760580
35cellular protein complex disassembly (GO:0043624)3.07943189
36tongue development (GO:0043586)3.02381343
37mechanosensory behavior (GO:0007638)3.01844389
38translational elongation (GO:0006414)3.00728629
39establishment of protein localization to mitochondrial membrane (GO:0090151)3.00475338
40regulation of cilium movement (GO:0003352)2.99239314
41negative regulation of response to food (GO:0032096)2.98035271
42negative regulation of appetite (GO:0032099)2.98035271
43pyrimidine nucleobase catabolic process (GO:0006208)2.97861751
44left/right pattern formation (GO:0060972)2.95824023
45dendritic spine morphogenesis (GO:0060997)2.91391097
46uterus development (GO:0060065)2.87723473
47retinal ganglion cell axon guidance (GO:0031290)2.86579391
48axon ensheathment in central nervous system (GO:0032291)2.85434317
49central nervous system myelination (GO:0022010)2.85434317
50cerebral cortex radially oriented cell migration (GO:0021799)2.83933485
51viral life cycle (GO:0019058)2.83170437
52mitochondrial respiratory chain complex assembly (GO:0033108)2.82579214
53epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287)2.80897080
54axonal fasciculation (GO:0007413)2.77507474
55positive regulation of cAMP-mediated signaling (GO:0043950)2.74121402
56synaptic transmission, cholinergic (GO:0007271)2.72568148
57postsynaptic membrane organization (GO:0001941)2.71281196
58presynaptic membrane organization (GO:0097090)2.71241253
59cilium movement (GO:0003341)2.69617500
60protein K6-linked ubiquitination (GO:0085020)2.69514978
61regulation of response to food (GO:0032095)2.68577407
62protein-cofactor linkage (GO:0018065)2.64417058
63positive regulation of male gonad development (GO:2000020)2.63195678
64short-term memory (GO:0007614)2.62654504
65alkaloid metabolic process (GO:0009820)2.60220034
66protein complex disassembly (GO:0043241)2.59028449
67insulin secretion (GO:0030073)2.57625561
68transmission of nerve impulse (GO:0019226)2.57517459
69spinal cord association neuron differentiation (GO:0021527)2.57511215
70regulation of timing of cell differentiation (GO:0048505)2.56636806
71maturation of SSU-rRNA (GO:0030490)2.56002685
72nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184)2.55164620
73macromolecular complex disassembly (GO:0032984)2.54620901
74hindbrain development (GO:0030902)2.54591044
75negative regulation of telomere maintenance (GO:0032205)2.53472152
76nephron tubule morphogenesis (GO:0072078)2.52815167
77nephron epithelium morphogenesis (GO:0072088)2.52815167
78chaperone-mediated protein transport (GO:0072321)2.50250058
79regulation of male gonad development (GO:2000018)2.49796406
80neuron recognition (GO:0008038)2.47434198
81pyrimidine deoxyribonucleotide catabolic process (GO:0009223)2.47299818
82ribosomal large subunit biogenesis (GO:0042273)2.47007128
83protein localization to synapse (GO:0035418)2.45770330
84auditory receptor cell stereocilium organization (GO:0060088)2.45581614
85neuronal action potential propagation (GO:0019227)2.43950677
86nucleobase catabolic process (GO:0046113)2.42517236
87behavioral response to ethanol (GO:0048149)2.42383569
88neuronal stem cell maintenance (GO:0097150)2.41910913
89cilium organization (GO:0044782)2.41368490
90axoneme assembly (GO:0035082)2.40929514
91translational initiation (GO:0006413)2.40732567
92chromatin remodeling at centromere (GO:0031055)2.40646903
93cilium assembly (GO:0042384)2.39226219
94limb bud formation (GO:0060174)2.38368856
95regulation of development, heterochronic (GO:0040034)2.35929871
96smoothened signaling pathway (GO:0007224)2.34426566
97response to auditory stimulus (GO:0010996)2.34093966
98dorsal/ventral pattern formation (GO:0009953)2.33302291
99cilium morphogenesis (GO:0060271)2.32804840
100regulation of appetite (GO:0032098)2.32618062

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1EZH2_22144423_ChIP-Seq_EOC_Human6.12820986
2HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse5.07111650
3RBPJ_22232070_ChIP-Seq_NCS_Mouse3.94460587
4NR4A2_19515692_ChIP-ChIP_MN9D_Mouse3.52105157
5CBX2_27304074_Chip-Seq_ESCs_Mouse2.54657722
6TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat2.49026914
7VDR_22108803_ChIP-Seq_LS180_Human2.48973994
8ZNF274_21170338_ChIP-Seq_K562_Hela2.46386537
9EZH2_27304074_Chip-Seq_ESCs_Mouse2.41591142
10GABP_17652178_ChIP-ChIP_JURKAT_Human2.39140447
11HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human2.34371403
12GBX2_23144817_ChIP-Seq_PC3_Human2.23423141
13SOX9_22984422_ChIP-ChIP_TESTIS_Rat2.12867836
14E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse2.11939912
15EED_16625203_ChIP-ChIP_MESCs_Mouse1.99960435
16EWS_26573619_Chip-Seq_HEK293_Human1.96072456
17JARID2_20064375_ChIP-Seq_MESCs_Mouse1.93292919
18KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human1.83985715
19FUS_26573619_Chip-Seq_HEK293_Human1.83431268
20ZFP57_27257070_Chip-Seq_ESCs_Mouse1.82829988
21RNF2_27304074_Chip-Seq_NSC_Mouse1.82135393
22CTBP1_25329375_ChIP-Seq_LNCAP_Human1.79002784
23BMI1_23680149_ChIP-Seq_NPCS_Mouse1.77851395
24CTBP2_25329375_ChIP-Seq_LNCAP_Human1.76252254
25SUZ12_18692474_ChIP-Seq_MESCs_Mouse1.73006224
26EZH2_27294783_Chip-Seq_ESCs_Mouse1.72833915
27CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons1.72489225
28MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.72182944
29SUZ12_16625203_ChIP-ChIP_MESCs_Mouse1.69403887
30EST1_17652178_ChIP-ChIP_JURKAT_Human1.68579875
31IGF1R_20145208_ChIP-Seq_DFB_Human1.66984487
32REST_21632747_ChIP-Seq_MESCs_Mouse1.65482100
33RNF2_27304074_Chip-Seq_ESCs_Mouse1.63418506
34JARID2_20075857_ChIP-Seq_MESCs_Mouse1.58806149
35SUZ12_18555785_ChIP-Seq_MESCs_Mouse1.58063496
36PHC1_16625203_ChIP-ChIP_MESCs_Mouse1.56653041
37SUZ12_18692474_ChIP-Seq_MEFs_Mouse1.55887322
38GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.55442370
39POU3F2_20337985_ChIP-ChIP_501MEL_Human1.50307492
40CHD7_19251738_ChIP-ChIP_MESCs_Mouse1.49801055
41SUZ12_27294783_Chip-Seq_ESCs_Mouse1.47863008
42GLI1_17442700_ChIP-ChIP_MESCs_Mouse1.45518396
43RNF2_18974828_ChIP-Seq_MESCs_Mouse1.45226670
44EZH2_18974828_ChIP-Seq_MESCs_Mouse1.45226670
45P300_19829295_ChIP-Seq_ESCs_Human1.41332280
46POU5F1_16153702_ChIP-ChIP_HESCs_Human1.38022196
47TAF15_26573619_Chip-Seq_HEK293_Human1.37861870
48ETS1_20019798_ChIP-Seq_JURKAT_Human1.36088653
49MYC_18940864_ChIP-ChIP_HL60_Human1.35359530
50MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human1.31309126
51RNF2_16625203_ChIP-ChIP_MESCs_Mouse1.30330736
52ZFP322A_24550733_ChIP-Seq_MESCs_Mouse1.30075716
53EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human1.25902346
54POU5F1_26923725_Chip-Seq_MESODERM_Mouse1.23737166
55TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.23737166
56TOP2B_26459242_ChIP-Seq_MCF-7_Human1.22453051
57MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse1.21818295
58TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.21534111
59REST_18959480_ChIP-ChIP_MESCs_Mouse1.19845587
60RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.19513132
61PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.19075837
62SUZ12_18974828_ChIP-Seq_MESCs_Mouse1.18937812
63TP53_20018659_ChIP-ChIP_R1E_Mouse1.15764033
64JARID1A_20064375_ChIP-Seq_MESCs_Mouse1.13382834
65SUZ12_20075857_ChIP-Seq_MESCs_Mouse1.13023998
66ELK1_19687146_ChIP-ChIP_HELA_Human1.11771044
67KLF4_25985364_ChIP-Seq_ATHEROSCLEROSIS_LESION_Mouse1.11630025
68RING1B_27294783_Chip-Seq_ESCs_Mouse1.08574387
69NR3C1_21868756_ChIP-Seq_MCF10A_Human1.07776264
70ETV2_25802403_ChIP-Seq_MESCs_Mouse1.06403246
71FOXP2_21765815_ChIP-ChIP_NEURO2A_Mouse1.06402111
72NOTCH1_17114293_ChIP-ChIP_T-ALL_Human1.06165185
73SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.04873202
74TP53_22573176_ChIP-Seq_HFKS_Human1.02584161
75SMAD4_21799915_ChIP-Seq_A2780_Human1.01913849
76SIN3B_21632747_ChIP-Seq_MESCs_Mouse1.01481489
77AR_25329375_ChIP-Seq_VCAP_Human1.00214676
78PIAS1_25552417_ChIP-Seq_VCAP_Human0.99777959
79MTF2_20144788_ChIP-Seq_MESCs_Mouse0.99586401
80CEBPB_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.99194074
81JUN_21703547_ChIP-Seq_K562_Human0.97364284
82P53_22127205_ChIP-Seq_FIBROBLAST_Human0.96600167
83SMAD2/3_21741376_ChIP-Seq_EPCs_Human0.95950147
84GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse0.95458477
85TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.95277515
86GATA1_26923725_Chip-Seq_HPCs_Mouse0.93284906
87CEBPD_23245923_ChIP-Seq_MEFs_Mouse0.92684577
88UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human0.90910545
89KLF5_20875108_ChIP-Seq_MESCs_Mouse0.90266470
90LMO2_26923725_Chip-Seq_MACROPHAGESS_Mouse0.88821640
91ER_23166858_ChIP-Seq_MCF-7_Human0.88550404
92OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse0.88276850
93TCF4_22108803_ChIP-Seq_LS180_Human0.85832484
94POU5F1_18358816_ChIP-ChIP_MESCs_Mouse0.85346313
95AR_21572438_ChIP-Seq_LNCaP_Human0.84976435
96SOX2_18555785_ChIP-Seq_MESCs_Mouse0.84235506
97TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human0.83519744
98SRF_21415370_ChIP-Seq_HL-1_Mouse0.83120271
99SMAD3_21741376_ChIP-Seq_EPCs_Human0.83075125
100RUNX2_22187159_ChIP-Seq_PCA_Human0.81713982

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0001986_abnormal_taste_sensitivity6.29412317
2MP0006292_abnormal_olfactory_placode4.50205954
3MP0002638_abnormal_pupillary_reflex2.76836874
4MP0003880_abnormal_central_pattern2.61644184
5MP0008789_abnormal_olfactory_epithelium2.51276637
6MP0003787_abnormal_imprinting2.35130485
7MP0003122_maternal_imprinting2.25453860
8MP0002938_white_spotting2.22056116
9MP0009379_abnormal_foot_pigmentation2.21344720
10MP0005083_abnormal_biliary_tract2.05807958
11MP0005187_abnormal_penis_morphology2.01601278
12MP0005394_taste/olfaction_phenotype2.00390204
13MP0005499_abnormal_olfactory_system2.00390204
14MP0000569_abnormal_digit_pigmentation1.92685787
15MP0002653_abnormal_ependyma_morphology1.91589822
16MP0003136_yellow_coat_color1.89028902
17MP0003011_delayed_dark_adaptation1.81823185
18MP0003121_genomic_imprinting1.81429273
19MP0000778_abnormal_nervous_system1.77252545
20MP0001529_abnormal_vocalization1.72979026
21MP0005551_abnormal_eye_electrophysiolog1.71341204
22MP0001984_abnormal_olfaction1.70876901
23MP0000372_irregular_coat_pigmentation1.66496150
24MP0001485_abnormal_pinna_reflex1.64171990
25MP0008877_abnormal_DNA_methylation1.63478730
26MP0009046_muscle_twitch1.61581539
27MP0005646_abnormal_pituitary_gland1.60852610
28MP0003123_paternal_imprinting1.59398217
29MP0003315_abnormal_perineum_morphology1.55739603
30MP0001968_abnormal_touch/_nociception1.53966665
31MP0002736_abnormal_nociception_after1.51791838
32MP0002234_abnormal_pharynx_morphology1.49823885
33MP0006072_abnormal_retinal_apoptosis1.46689267
34MP0002272_abnormal_nervous_system1.42136162
35MP0000049_abnormal_middle_ear1.41782032
36MP0001293_anophthalmia1.41374718
37MP0010030_abnormal_orbit_morphology1.41303143
38MP0004142_abnormal_muscle_tone1.35950650
39MP0004133_heterotaxia1.35787633
40MP0002557_abnormal_social/conspecific_i1.34667446
41MP0004885_abnormal_endolymph1.31823253
42MP0005171_absent_coat_pigmentation1.30917567
43MP0000631_abnormal_neuroendocrine_gland1.28720852
44MP0002160_abnormal_reproductive_system1.28485356
45MP0001919_abnormal_reproductive_system1.27506968
46MP0005389_reproductive_system_phenotype1.26422631
47MP0002184_abnormal_innervation1.25571667
48MP0005084_abnormal_gallbladder_morpholo1.24956926
49MP0009745_abnormal_behavioral_response1.23841909
50MP0002102_abnormal_ear_morphology1.20240799
51MP0000026_abnormal_inner_ear1.20003075
52MP0005253_abnormal_eye_physiology1.19934946
53MP0001486_abnormal_startle_reflex1.19174133
54MP0001905_abnormal_dopamine_level1.17253258
55MP0005423_abnormal_somatic_nervous1.16238161
56MP0002822_catalepsy1.15800244
57MP0006276_abnormal_autonomic_nervous1.15713800
58MP0002233_abnormal_nose_morphology1.13108367
59MP0002064_seizures1.12242789
60MP0002752_abnormal_somatic_nervous1.11250107
61MP0000955_abnormal_spinal_cord1.09230495
62MP0002572_abnormal_emotion/affect_behav1.09038513
63MP0005391_vision/eye_phenotype1.04059939
64MP0003635_abnormal_synaptic_transmissio1.03564764
65MP0004742_abnormal_vestibular_system0.99057270
66MP0005377_hearing/vestibular/ear_phenot0.95433522
67MP0003878_abnormal_ear_physiology0.95433522
68MP0005195_abnormal_posterior_eye0.95429355
69MP0004145_abnormal_muscle_electrophysio0.93916228
70MP0001970_abnormal_pain_threshold0.93507764
71MP0002063_abnormal_learning/memory/cond0.93379181
72MP0003186_abnormal_redox_activity0.93099673
73MP0002067_abnormal_sensory_capabilities0.92547306
74MP0003938_abnormal_ear_development0.92381252
75MP0002734_abnormal_mechanical_nocicepti0.91451184
76MP0002837_dystrophic_cardiac_calcinosis0.91361587
77MP0002882_abnormal_neuron_morphology0.91308150
78MP0000639_abnormal_adrenal_gland0.90751000
79MP0002733_abnormal_thermal_nociception0.90339733
80MP0003942_abnormal_urinary_system0.90322865
81MP0003755_abnormal_palate_morphology0.89600099
82MP0002876_abnormal_thyroid_physiology0.88886828
83MP0002095_abnormal_skin_pigmentation0.87692610
84MP0002735_abnormal_chemical_nociception0.86925110
85MP0001963_abnormal_hearing_physiology0.83038894
86MP0001502_abnormal_circadian_rhythm0.81878786
87MP0005645_abnormal_hypothalamus_physiol0.80961522
88MP0001324_abnormal_eye_pigmentation0.80405490
89MP0005503_abnormal_tendon_morphology0.79825149
90MP0004859_abnormal_synaptic_plasticity0.78863114
91MP0002152_abnormal_brain_morphology0.77056090
92MP0005386_behavior/neurological_phenoty0.75378118
93MP0004924_abnormal_behavior0.75378118
94MP0005257_abnormal_intraocular_pressure0.75150360
95MP0002092_abnormal_eye_morphology0.74924073
96MP0009250_abnormal_appendicular_skeleto0.74306974
97MP0005248_abnormal_Harderian_gland0.74121234
98MP0000534_abnormal_ureter_morphology0.73569921
99MP0008058_abnormal_DNA_repair0.73382028
100MP0001286_abnormal_eye_development0.72242292

Predicted human phenotypes

RankGene SetZ-score
1Enlarged penis (HP:0000040)4.14583789
2Acute necrotizing encephalopathy (HP:0006965)4.00649460
3Septo-optic dysplasia (HP:0100842)3.83113648
4True hermaphroditism (HP:0010459)3.67878538
5Reticulocytopenia (HP:0001896)3.60307529
6Pancreatic fibrosis (HP:0100732)3.54221936
7Abnormal mitochondria in muscle tissue (HP:0008316)3.54158762
8Abnormality of cells of the erythroid lineage (HP:0012130)3.52012394
9Nephronophthisis (HP:0000090)3.32278417
10Progressive macrocephaly (HP:0004481)3.24182234
11Acute encephalopathy (HP:0006846)3.22096354
12Degeneration of the lateral corticospinal tracts (HP:0002314)3.16622640
13Atrophy/Degeneration involving the corticospinal tracts (HP:0007372)3.16622640
14Abnormal number of erythroid precursors (HP:0012131)3.14699097
15Molar tooth sign on MRI (HP:0002419)3.13332480
16Abnormality of midbrain morphology (HP:0002418)3.13332480
17Medial flaring of the eyebrow (HP:0010747)3.10941514
18Pancreatic cysts (HP:0001737)3.07587377
19Abnormality of the renal medulla (HP:0100957)3.00237187
20Congenital stationary night blindness (HP:0007642)2.97917667
21Mitochondrial inheritance (HP:0001427)2.84263082
22Gait imbalance (HP:0002141)2.79674203
23Abnormal rod and cone electroretinograms (HP:0008323)2.74449144
24Optic nerve hypoplasia (HP:0000609)2.74361305
25Sclerocornea (HP:0000647)2.71610045
26Abnormality of the corticospinal tract (HP:0002492)2.64680457
27Increased CSF lactate (HP:0002490)2.64426054
28Congenital primary aphakia (HP:0007707)2.61263427
293-Methylglutaconic aciduria (HP:0003535)2.56796451
30Type II lissencephaly (HP:0007260)2.56170250
31Oligodactyly (hands) (HP:0001180)2.55096814
32Limb dystonia (HP:0002451)2.54983938
33Focal motor seizures (HP:0011153)2.52283413
34Absent septum pellucidum (HP:0001331)2.45526325
35Gonadotropin excess (HP:0000837)2.44653300
36Rib fusion (HP:0000902)2.40328069
37Aplasia/Hypoplasia of the optic nerve (HP:0008058)2.40054386
38Progressive microcephaly (HP:0000253)2.39268559
39Anophthalmia (HP:0000528)2.37081853
40Absent rod-and cone-mediated responses on ERG (HP:0007688)2.36997446
41Cerebral edema (HP:0002181)2.34755475
42Ectopic kidney (HP:0000086)2.34112040
43Absent thumb (HP:0009777)2.31502512
44Macrocytic anemia (HP:0001972)2.31501038
45Aplasia/Hypoplasia of the tongue (HP:0010295)2.31425674
46Retinal dysplasia (HP:0007973)2.30492322
47Oligodactyly (HP:0012165)2.28819475
48Nephrogenic diabetes insipidus (HP:0009806)2.26169887
49Postaxial foot polydactyly (HP:0001830)2.22324163
50Bilateral microphthalmos (HP:0007633)2.16031198
51Cystic liver disease (HP:0006706)2.12280987
52Congenital hepatic fibrosis (HP:0002612)2.11095635
53Decreased testicular size (HP:0008734)2.11038819
54Hepatocellular necrosis (HP:0001404)2.07656552
55Median cleft lip (HP:0000161)2.06766968
56Myokymia (HP:0002411)2.06204720
57Absence seizures (HP:0002121)2.05025863
58Chronic hepatic failure (HP:0100626)2.01198917
59Genital tract atresia (HP:0001827)2.00331186
60Male pseudohermaphroditism (HP:0000037)1.99687452
61Fibular hypoplasia (HP:0003038)1.98021327
62Aplasia/Hypoplasia of the tibia (HP:0005772)1.95302191
63Abnormality of the diencephalon (HP:0010662)1.94485300
64Postaxial hand polydactyly (HP:0001162)1.94316178
65Pendular nystagmus (HP:0012043)1.94052201
66Hypothermia (HP:0002045)1.93904296
67Vaginal atresia (HP:0000148)1.93521702
68Abnormality of DNA repair (HP:0003254)1.92316575
69Dialeptic seizures (HP:0011146)1.92215322
70Supernumerary spleens (HP:0009799)1.91893430
71Focal seizures (HP:0007359)1.90133057
72Short tibia (HP:0005736)1.89995620
73Aplasia/Hypoplasia of the sacrum (HP:0008517)1.88705233
74Optic disc pallor (HP:0000543)1.88636592
75Tubular atrophy (HP:0000092)1.87057978
76Hyperventilation (HP:0002883)1.84422793
77Hypoplasia of the fovea (HP:0007750)1.82258439
78Aplasia/Hypoplasia of the fovea (HP:0008060)1.82258439
79Adrenal hypoplasia (HP:0000835)1.81715263
80Tubulointerstitial nephritis (HP:0001970)1.79794398
81Hepatic necrosis (HP:0002605)1.79495240
82Polyphagia (HP:0002591)1.79030540
83Aplasia/Hypoplasia of the fibula (HP:0006492)1.78027350
84Abnormality of the septum pellucidum (HP:0007375)1.76143716
85Holoprosencephaly (HP:0001360)1.75523149
86Left ventricular hypertrophy (HP:0001712)1.74989332
87Aganglionic megacolon (HP:0002251)1.73960585
88Aplasia/Hypoplasia of the spleen (HP:0010451)1.73683711
89Bony spicule pigmentary retinopathy (HP:0007737)1.73594466
90Poor suck (HP:0002033)1.73566795
91Atonic seizures (HP:0010819)1.73492264
92Hypoplasia of the ulna (HP:0003022)1.73120207
93Anencephaly (HP:0002323)1.72937328
94Optic nerve coloboma (HP:0000588)1.72427371
95Concave nail (HP:0001598)1.71941292
96Amblyopia (HP:0000646)1.71707246
97Hypoplastic pelvis (HP:0008839)1.70892849
98Aplasia/hypoplasia of the uterus (HP:0008684)1.69854754
99Exercise intolerance (HP:0003546)1.67050573
100Spastic tetraplegia (HP:0002510)1.66401725

Predicted kinase interactions (KEA)

RankGene SetZ-score
1MAPK132.75589630
2CASK2.63278249
3EPHA42.47688545
4PINK12.39449388
5ABL22.35673325
6MAP4K22.10596927
7EPHB22.09830713
8WNK42.09227190
9MARK12.08628442
10ZAK1.88920061
11DAPK21.86514118
12MAP3K41.79630781
13PAK31.74048385
14STK161.67829929
15NTRK31.66994614
16NUAK11.66225427
17MAP2K71.57508882
18PLK21.55077234
19PRKCG1.53795181
20CDC71.52139740
21FRK1.51660298
22GRK11.51067434
23ADRBK21.49686435
24BCKDK1.48253557
25DYRK21.47107972
26CAMKK21.43801956
27TLK11.40537561
28WNK31.37463093
29WEE11.37396902
30MINK11.34018322
31DMPK1.32051599
32STK391.30182273
33CCNB11.26934378
34PNCK1.26443936
35LIMK11.25522882
36TAOK31.17876041
37PHKG11.06697540
38PHKG21.06697540
39ADRBK11.06377614
40NTRK21.04637894
41PRKCE1.04173236
42DYRK31.01685351
43BCR1.00180058
44MAPK150.98904969
45CAMK10.97975256
46BMPR1B0.97918223
47PLK40.96233950
48EIF2AK10.89654746
49MUSK0.88361113
50CSNK1G20.85756697
51CAMK2A0.82557259
52RPS6KA40.81849065
53VRK10.79356807
54CAMK2G0.78635474
55TIE10.77596854
56INSRR0.77026939
57PKN10.76721993
58CAMK2D0.76058900
59NME10.75988638
60CHUK0.72069969
61DYRK1B0.70285226
62OBSCN0.69453200
63STK38L0.66711768
64PRKACA0.66041819
65MAP3K90.65611408
66CSNK1G30.64039658
67AURKA0.63795932
68LRRK20.63151123
69PLK30.63108457
70GRK70.63025905
71PAK60.63005533
72CSNK1A10.61558751
73PTK2B0.60747565
74TNIK0.59323584
75MARK20.57895387
76CAMK2B0.57433678
77MAPKAPK50.54761407
78MKNK20.53727773
79KSR10.52301795
80AURKB0.50639040
81CDK30.50185254
82CSNK1E0.49875453
83LATS10.49858376
84PRKCZ0.49284647
85PIK3CA0.48437000
86DYRK1A0.48178362
87PLK10.46967727
88CAMKK10.46117737
89ROCK10.45101169
90CSNK2A20.44337027
91TGFBR10.44250695
92EIF2AK30.43893781
93PRKD30.43702861
94CSNK1G10.43609522
95PRKACB0.43531668
96AKT30.43155696
97CSNK2A10.42901167
98MAP3K70.41910288
99CDK180.41616522
100CDK11A0.40830260

Predicted pathways (KEGG)

RankGene SetZ-score
1Ribosome_Homo sapiens_hsa030104.13004173
2Oxidative phosphorylation_Homo sapiens_hsa001903.92567622
3Parkinsons disease_Homo sapiens_hsa050123.34897429
4Protein export_Homo sapiens_hsa030603.08065140
5Phototransduction_Homo sapiens_hsa047442.44295345
6Alzheimers disease_Homo sapiens_hsa050102.31348571
7Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001302.26597601
8Cardiac muscle contraction_Homo sapiens_hsa042602.25359482
9Huntingtons disease_Homo sapiens_hsa050162.23500379
10Homologous recombination_Homo sapiens_hsa034402.20828671
11Synthesis and degradation of ketone bodies_Homo sapiens_hsa000722.06684935
12Insulin secretion_Homo sapiens_hsa049112.01632211
13Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005631.95925160
14Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049321.83966316
15Steroid biosynthesis_Homo sapiens_hsa001001.77791663
16Fanconi anemia pathway_Homo sapiens_hsa034601.76513053
17Nicotine addiction_Homo sapiens_hsa050331.73133740
18Proteasome_Homo sapiens_hsa030501.64554191
19Maturity onset diabetes of the young_Homo sapiens_hsa049501.52373711
20Taurine and hypotaurine metabolism_Homo sapiens_hsa004301.51145838
21Basal cell carcinoma_Homo sapiens_hsa052171.46002203
22Hedgehog signaling pathway_Homo sapiens_hsa043401.41294066
23RNA polymerase_Homo sapiens_hsa030201.37535868
24Primary bile acid biosynthesis_Homo sapiens_hsa001201.34538971
25Neuroactive ligand-receptor interaction_Homo sapiens_hsa040801.33384386
26Folate biosynthesis_Homo sapiens_hsa007901.32061540
27Olfactory transduction_Homo sapiens_hsa047401.30576045
28Butanoate metabolism_Homo sapiens_hsa006501.30314955
29Morphine addiction_Homo sapiens_hsa050321.26932657
30Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007601.25990827
31Cocaine addiction_Homo sapiens_hsa050301.23363521
32Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005341.19496022
33Basal transcription factors_Homo sapiens_hsa030221.15668479
34Dopaminergic synapse_Homo sapiens_hsa047281.15340166
35Mismatch repair_Homo sapiens_hsa034301.14932183
36Terpenoid backbone biosynthesis_Homo sapiens_hsa009001.13971361
37Circadian entrainment_Homo sapiens_hsa047131.13821826
38Ovarian steroidogenesis_Homo sapiens_hsa049131.08763529
39Pyrimidine metabolism_Homo sapiens_hsa002401.08175736
40Glutamatergic synapse_Homo sapiens_hsa047241.05505361
41Retrograde endocannabinoid signaling_Homo sapiens_hsa047231.05095555
42Nucleotide excision repair_Homo sapiens_hsa034201.03897841
43DNA replication_Homo sapiens_hsa030301.01996300
44Base excision repair_Homo sapiens_hsa034101.01330451
45GABAergic synapse_Homo sapiens_hsa047271.00435387
46Sulfur relay system_Homo sapiens_hsa041221.00310172
47Amphetamine addiction_Homo sapiens_hsa050310.98477423
48Fatty acid elongation_Homo sapiens_hsa000620.98138167
49Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006300.96095456
50Propanoate metabolism_Homo sapiens_hsa006400.91418650
51Vasopressin-regulated water reabsorption_Homo sapiens_hsa049620.89182977
52Valine, leucine and isoleucine degradation_Homo sapiens_hsa002800.88938316
53Collecting duct acid secretion_Homo sapiens_hsa049660.82788540
54Calcium signaling pathway_Homo sapiens_hsa040200.80092873
55Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.79973563
56Purine metabolism_Homo sapiens_hsa002300.78920167
57Selenocompound metabolism_Homo sapiens_hsa004500.76260493
58Hippo signaling pathway_Homo sapiens_hsa043900.71386550
59Pyruvate metabolism_Homo sapiens_hsa006200.70331906
60Axon guidance_Homo sapiens_hsa043600.69154468
61Metabolic pathways_Homo sapiens_hsa011000.68302908
62Serotonergic synapse_Homo sapiens_hsa047260.66095476
63One carbon pool by folate_Homo sapiens_hsa006700.65789499
64Ascorbate and aldarate metabolism_Homo sapiens_hsa000530.65542796
65Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.65065266
66Peroxisome_Homo sapiens_hsa041460.64623039
67Regulation of autophagy_Homo sapiens_hsa041400.64517952
68Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010400.63259819
69Synaptic vesicle cycle_Homo sapiens_hsa047210.63168933
70RNA degradation_Homo sapiens_hsa030180.58935661
71Melanogenesis_Homo sapiens_hsa049160.58591168
72Aldosterone synthesis and secretion_Homo sapiens_hsa049250.58525749
73Tryptophan metabolism_Homo sapiens_hsa003800.58201248
74Taste transduction_Homo sapiens_hsa047420.57360180
75Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.54056306
76Cholinergic synapse_Homo sapiens_hsa047250.52425297
77Nitrogen metabolism_Homo sapiens_hsa009100.51955629
78Alcoholism_Homo sapiens_hsa050340.51383378
79Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.50622014
80Wnt signaling pathway_Homo sapiens_hsa043100.49399868
81Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009700.47956992
82Spliceosome_Homo sapiens_hsa030400.45347330
83Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042610.45340386
84Long-term depression_Homo sapiens_hsa047300.43877636
85Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.43753644
86Thyroid hormone synthesis_Homo sapiens_hsa049180.43509207
87Salivary secretion_Homo sapiens_hsa049700.43390897
88Gastric acid secretion_Homo sapiens_hsa049710.42833866
89Linoleic acid metabolism_Homo sapiens_hsa005910.42169482
90Glutathione metabolism_Homo sapiens_hsa004800.41664477
91Cysteine and methionine metabolism_Homo sapiens_hsa002700.39350951
92alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.37846159
93beta-Alanine metabolism_Homo sapiens_hsa004100.34472302
94Oxytocin signaling pathway_Homo sapiens_hsa049210.32623822
95Renin secretion_Homo sapiens_hsa049240.32413647
96Ether lipid metabolism_Homo sapiens_hsa005650.31491081
97Sulfur metabolism_Homo sapiens_hsa009200.30654994
98Vitamin B6 metabolism_Homo sapiens_hsa007500.29972626
99cAMP signaling pathway_Homo sapiens_hsa040240.29622072
100Arginine and proline metabolism_Homo sapiens_hsa003300.28467113

Most similar genes based on co-expression Upload to Enrichr

Tissue Expression Export image »

Cell Line Expression Export image »