RNPEP

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1COPI coating of Golgi vesicle (GO:0048205)5.05520978
2Golgi transport vesicle coating (GO:0048200)5.05520978
3positive regulation by symbiont of host defense response (GO:0052509)4.86261054
4modulation by symbiont of host defense response (GO:0052031)4.86261054
5modulation by organism of immune response of other organism involved in symbiotic interaction (GO:004.86261054
6modulation by organism of defense response of other organism involved in symbiotic interaction (GO:04.86261054
7positive regulation by organism of defense response of other organism involved in symbiotic interact4.86261054
8modulation by symbiont of host immune response (GO:0052553)4.86261054
9antigen processing and presentation of endogenous peptide antigen (GO:0002483)4.40082963
10antigen processing and presentation of endogenous peptide antigen via MHC class I (GO:0019885)4.40082963
11response to peptidoglycan (GO:0032494)4.36057185
12neutrophil activation involved in immune response (GO:0002283)4.26687498
13immunoglobulin mediated immune response (GO:0016064)4.18709132
14regulation of interferon-beta biosynthetic process (GO:0045357)4.04959948
15Arp2/3 complex-mediated actin nucleation (GO:0034314)3.96030887
16antigen processing and presentation of endogenous antigen (GO:0019883)3.95682981
17respiratory burst (GO:0045730)3.82528553
18positive regulation of interferon-alpha production (GO:0032727)3.74649949
19regulation of antigen processing and presentation of peptide antigen (GO:0002583)3.71318039
20positive regulation of Cdc42 GTPase activity (GO:0043089)3.64863734
21positive regulation of interleukin-8 biosynthetic process (GO:0045416)3.63874381
22barbed-end actin filament capping (GO:0051016)3.55921770
23regulation of interferon-alpha production (GO:0032647)3.53212505
24glycosphingolipid catabolic process (GO:0046479)3.50748551
25positive regulation of antigen processing and presentation (GO:0002579)3.49046030
26regulation of early endosome to late endosome transport (GO:2000641)3.45245962
27neutrophil mediated immunity (GO:0002446)3.42305082
28negative regulation of erythrocyte differentiation (GO:0045647)3.41107498
29macrophage activation involved in immune response (GO:0002281)3.40399025
30response to immune response of other organism involved in symbiotic interaction (GO:0052564)3.33991966
31response to host immune response (GO:0052572)3.33991966
32response to fungus (GO:0009620)3.31892320
33B cell mediated immunity (GO:0019724)3.25397388
34regulation of interleukin-8 biosynthetic process (GO:0045414)3.25240444
35cellular extravasation (GO:0045123)3.23197654
36glycolipid catabolic process (GO:0019377)3.18769161
37negative regulation of endoplasmic reticulum calcium ion concentration (GO:0032471)3.18510095
38protein localization to endosome (GO:0036010)3.18399132
39response to muramyl dipeptide (GO:0032495)3.16911217
40production of molecular mediator involved in inflammatory response (GO:0002532)3.15904481
41pinocytosis (GO:0006907)3.15464641
42proline biosynthetic process (GO:0006561)3.13862804
43antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G3.12558736
44maintenance of protein localization in endoplasmic reticulum (GO:0035437)3.12224858
45retrograde vesicle-mediated transport, Golgi to ER (GO:0006890)3.10920279
46protein retention in ER lumen (GO:0006621)3.10502512
47neutrophil activation (GO:0042119)3.10131531
48DNA deamination (GO:0045006)3.07928682
49pentose-phosphate shunt (GO:0006098)3.07156025
50response to defenses of other organism involved in symbiotic interaction (GO:0052173)3.02816088
51response to host (GO:0075136)3.02816088
52response to host defenses (GO:0052200)3.02816088
53mitotic chromosome condensation (GO:0007076)3.01757289
54actin nucleation (GO:0045010)2.99112235
55negative regulation of phagocytosis (GO:0050765)2.98997618
56positive regulation of B cell differentiation (GO:0045579)2.98939357
57regulation of antigen processing and presentation (GO:0002577)2.98253539
58* leukotriene metabolic process (GO:0006691)2.96877410
59superoxide anion generation (GO:0042554)2.96609460
60glucose 6-phosphate metabolic process (GO:0051156)2.95611049
61granulocyte activation (GO:0036230)2.95526640
62regulation of B cell receptor signaling pathway (GO:0050855)2.92747325
63negative regulation of interleukin-12 production (GO:0032695)2.92208192
64defense response to fungus (GO:0050832)2.92132644
65positive regulation of gamma-delta T cell activation (GO:0046645)2.89883359
66positive regulation of interferon-beta production (GO:0032728)2.89281536
67hepatocyte apoptotic process (GO:0097284)2.86809178
68response to laminar fluid shear stress (GO:0034616)2.85767865
69response to thyroid hormone (GO:0097066)2.83702916
70desmosome organization (GO:0002934)2.83410800
71NADPH regeneration (GO:0006740)2.80778088
72mannose metabolic process (GO:0006013)2.80528614
73cellular response to thyroid hormone stimulus (GO:0097067)2.77775396
74regulation of superoxide anion generation (GO:0032928)2.77422524
75antigen processing and presentation via MHC class Ib (GO:0002475)2.77094541
76detection of molecule of bacterial origin (GO:0032490)2.76851935
77embryonic process involved in female pregnancy (GO:0060136)2.76780614
78reactive oxygen species biosynthetic process (GO:1903409)2.75658305
79protein maturation by protein folding (GO:0022417)2.74037924
80epithelial cell-cell adhesion (GO:0090136)2.73802641
81leukocyte mediated cytotoxicity (GO:0001909)2.71065540
82hyaluronan catabolic process (GO:0030214)2.70437648
83lipopolysaccharide-mediated signaling pathway (GO:0031663)2.68528385
84negative regulation of granulocyte differentiation (GO:0030853)2.67341444
85interferon-gamma secretion (GO:0072643)2.66172281
86regulation of mast cell degranulation (GO:0043304)2.65760531
87stress fiber assembly (GO:0043149)2.62494589
88NIK/NF-kappaB signaling (GO:0038061)2.61983616
89regulation of mammary gland epithelial cell proliferation (GO:0033599)2.61586623
90regulation of mast cell activation (GO:0033003)2.60363882
91myeloid leukocyte mediated immunity (GO:0002444)2.60001869
92negative regulation of growth of symbiont in host (GO:0044130)2.59436939
93negative regulation of growth of symbiont involved in interaction with host (GO:0044146)2.59436939
94modulation of growth of symbiont involved in interaction with host (GO:0044144)2.59436939
95regulation of growth of symbiont in host (GO:0044126)2.59436939
96epithelial cell differentiation involved in prostate gland development (GO:0060742)2.59111562
97apoptotic process involved in morphogenesis (GO:0060561)2.58656340
98ceramide catabolic process (GO:0046514)2.58367655
99myeloid cell activation involved in immune response (GO:0002275)2.58345088
100maternal placenta development (GO:0001893)2.58224066
101hypotonic response (GO:0006971)2.57324018
102NADH metabolic process (GO:0006734)2.56055168
103activation of Rac GTPase activity (GO:0032863)2.55791242
104mitochondrial calcium ion transport (GO:0006851)2.55672482
105response to interferon-beta (GO:0035456)2.55343193
106positive regulation of membrane protein ectodomain proteolysis (GO:0051044)2.53831383
107lipoxygenase pathway (GO:0019372)2.53784513
108mature B cell differentiation involved in immune response (GO:0002313)2.53756300
109regulation of tumor necrosis factor biosynthetic process (GO:0042534)2.52799469
110adhesion of symbiont to host (GO:0044406)2.52597939
111type I interferon signaling pathway (GO:0060337)2.52328916
112cellular response to type I interferon (GO:0071357)2.52328916
113peptide catabolic process (GO:0043171)2.50933333
114negative regulation of myeloid cell apoptotic process (GO:0033033)2.50726589
115amyloid precursor protein catabolic process (GO:0042987)2.50201382
116macrophage activation (GO:0042116)2.50067648
117response to type I interferon (GO:0034340)2.49892029
118leukocyte aggregation (GO:0070486)2.48911166
119regulation of cellular extravasation (GO:0002691)2.48510884
120activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c (GO2.47832630
121hemidesmosome assembly (GO:0031581)2.47673095
122glucose catabolic process (GO:0006007)2.47563321
123myeloid dendritic cell activation (GO:0001773)2.47203040
124regulation of mast cell activation involved in immune response (GO:0033006)2.46574648
125regulation of dendritic cell antigen processing and presentation (GO:0002604)2.46064609
126response to protozoan (GO:0001562)2.44831144
127response to interferon-alpha (GO:0035455)2.44819232
128urea cycle (GO:0000050)2.44628640
129regulation of RIG-I signaling pathway (GO:0039535)2.44098515
130basement membrane organization (GO:0071711)2.43418869
131defense response to protozoan (GO:0042832)2.43301894
132hydrogen peroxide biosynthetic process (GO:0050665)2.43282910
133virion attachment to host cell (GO:0019062)2.41938298
134adhesion of symbiont to host cell (GO:0044650)2.41938298
135GDP-mannose metabolic process (GO:0019673)2.40714639
136regulation of interferon-beta production (GO:0032648)2.40537039
137cellular response to interferon-beta (GO:0035458)2.38207378
138detection of other organism (GO:0098543)2.37968185
139modulation by symbiont of host cellular process (GO:0044068)2.37951708
140disruption of cells of other organism involved in symbiotic interaction (GO:0051818)2.37232787
141killing of cells in other organism involved in symbiotic interaction (GO:0051883)2.37232787
142negative regulation of mast cell activation (GO:0033004)2.37068224
143sphingolipid catabolic process (GO:0030149)2.37029523
144branching involved in mammary gland duct morphogenesis (GO:0060444)2.36098980
145natural killer cell mediated immunity (GO:0002228)2.35831478
146natural killer cell mediated cytotoxicity (GO:0042267)2.35831478
147detection of bacterium (GO:0016045)2.35231485
148positive regulation of syncytium formation by plasma membrane fusion (GO:0060143)2.34923120
149apoptotic cell clearance (GO:0043277)2.34511074
150regulation of leukocyte degranulation (GO:0043300)2.33785583
151membrane lipid catabolic process (GO:0046466)2.33009608
152negative regulation of protein localization to plasma membrane (GO:1903077)2.31659416
153pentose metabolic process (GO:0019321)2.31424008
154oligosaccharide catabolic process (GO:0009313)2.30251282
155embryo implantation (GO:0007566)2.28170410
156formation of translation preinitiation complex (GO:0001731)2.26502432
157urea metabolic process (GO:0019627)2.25366859
158regulation of apoptotic process involved in morphogenesis (GO:1902337)2.24855344
159negative regulation of viral release from host cell (GO:1902187)2.24567079
160activation of signaling protein activity involved in unfolded protein response (GO:0006987)2.23919323
161positive regulation of nuclease activity (GO:0032075)2.23455771
162cell-substrate junction assembly (GO:0007044)2.22823218
163skin morphogenesis (GO:0043589)2.19860278
164regulation of extracellular matrix disassembly (GO:0010715)2.17959883
165vesicle coating (GO:0006901)2.17630077
166regulation of vitamin metabolic process (GO:0030656)2.17465697
167negative regulation of toll-like receptor 4 signaling pathway (GO:0034144)2.17384175
168positive regulation of leukocyte degranulation (GO:0043302)2.15758892
169regulation of podosome assembly (GO:0071801)2.15575861
170positive regulation of keratinocyte differentiation (GO:0045618)2.15314344
171adherens junction assembly (GO:0034333)2.14648284
172regulation of Arp2/3 complex-mediated actin nucleation (GO:0034315)2.14104097
173positive regulation of receptor recycling (GO:0001921)2.13370330
174angiotensin maturation (GO:0002003)2.12814417
175pyrimidine-containing compound salvage (GO:0008655)2.12599506
176pyrimidine nucleoside salvage (GO:0043097)2.12599506
177COPII vesicle coating (GO:0048208)2.12053524
178endoplasmic reticulum calcium ion homeostasis (GO:0032469)2.12022727
179cellular protein complex localization (GO:0034629)2.11865409
180regulation of integrin activation (GO:0033623)2.10870317

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1E2F7_22180533_ChIP-Seq_HELA_Human4.90311233
2IRF8_21731497_ChIP-ChIP_J774_Mouse4.08103540
3IRF8_22096565_ChIP-ChIP_GC-B_Human3.92156812
4EGR1_19374776_ChIP-ChIP_THP-1_Human2.77783907
5BP1_19119308_ChIP-ChIP_Hs578T_Human2.77627901
6MYB_21317192_ChIP-Seq_ERMYB_Mouse2.74587113
7MECOM_23826213_ChIP-Seq_KASUMI_Mouse2.71049588
8IRF8_27001747_Chip-Seq_BMDM_Mouse2.64448804
9* SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse2.62944626
10* NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse2.46298591
11NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human2.43151320
12IRF8_22096565_ChIP-ChIP_GC-B_Mouse2.40292448
13ZNF263_19887448_ChIP-Seq_K562_Human2.31256883
14SPI1_22096565_ChIP-ChIP_GC-B_Mouse2.25168039
15* EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse2.23936930
16VDR_21846776_ChIP-Seq_THP-1_Human2.18645699
17STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse2.16371184
18* SPI1_23547873_ChIP-Seq_NB4_Human2.14056337
19SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse2.13679212
20* BRD4_27068464_Chip-Seq_AML-cells_Mouse2.09076865
21IRF1_21803131_ChIP-Seq_MONOCYTES_Human2.05199648
22* RUNX1_20887958_ChIP-Seq_HPC-7_Mouse1.98220098
23TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat1.95152105
24FLI1_20887958_ChIP-Seq_HPC-7_Mouse1.90556955
25TP63_17297297_ChIP-ChIP_HaCaT_Human1.88130443
26STAT5_23275557_ChIP-Seq_MAMMARY-EPITHELIUM_Mouse1.83425937
27CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human1.79996347
28VDR_24763502_ChIP-Seq_THP-1_Human1.79754479
29FOXM1_23109430_ChIP-Seq_U2OS_Human1.78377374
30ASXL1_24218140_ChIP-Seq_BMDM_Mouse1.77185689
31* KDM2B_26808549_Chip-Seq_SIL-ALL_Human1.76826068
32RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human1.76410011
33MYC_22102868_ChIP-Seq_BL_Human1.73149835
34SCL_19346495_ChIP-Seq_HPC-7_Human1.71567226
35Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse1.71544744
36STAT4_19710469_ChIP-ChIP_TH1__Mouse1.69601313
37SFPI1_20887958_ChIP-Seq_HPC-7_Mouse1.68607767
38STAT6_20620947_ChIP-Seq_CD4_POS_T_Human1.68222565
39KLF4_26769127_Chip-Seq_PDAC-Cell_line_Human1.67960530
40RUNX1_22412390_ChIP-Seq_EML_Mouse1.64736027
41NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse1.61788811
42MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse1.58454679
43ELF1_17652178_ChIP-ChIP_JURKAT_Human1.58262452
44MAF_26560356_Chip-Seq_TH1_Human1.56278222
45* KDM2B_26808549_Chip-Seq_SUP-B15_Human1.55199257
46TAL1_20887958_ChIP-Seq_HPC-7_Mouse1.55039222
47CLOCK_20551151_ChIP-Seq_293T_Human1.52703639
48SOX9_22984422_ChIP-ChIP_TESTIS_Rat1.50838630
49THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse1.50382292
50MYC_18555785_ChIP-Seq_MESCs_Mouse1.49616735
51NOTCH1_17114293_ChIP-ChIP_T-ALL_Human1.47444613
52MEIS1_20887958_ChIP-Seq_HPC-7_Mouse1.47320912
53KLF4_18358816_ChIP-ChIP_MESCs_Mouse1.47259880
54PPARG_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse1.47190592
55DACH1_20351289_ChIP-Seq_MDA-MB-231_Human1.45445692
56MYB_26560356_Chip-Seq_TH2_Human1.43045004
57KLF4_18555785_ChIP-Seq_MESCs_Mouse1.42404026
58FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human1.39270134
59ATF3_27146783_Chip-Seq_COLON_Human1.38839360
60HCFC1_20581084_ChIP-Seq_MESCs_Mouse1.37912993
61CEBPB_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse1.37773366
62SPI1_23127762_ChIP-Seq_K562_Human1.32338520
63* KDM2B_26808549_Chip-Seq_DND41_Human1.32303475
64MYB_26560356_Chip-Seq_TH1_Human1.31740497
65PPARG_19300518_ChIP-PET_3T3-L1_Mouse1.31369859
66UTX_26944678_Chip-Seq_JUKART_Human1.31369584
67GATA1_22383799_ChIP-Seq_G1ME_Mouse1.31299092
68E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human1.30664610
69* TCFAP2C_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse1.30331452
70ESR2_21235772_ChIP-Seq_MCF-7_Human1.29873222
71STAT3_20064451_ChIP-Seq_CD4+T_Mouse1.29473024
72* SMARCA4_20176728_ChIP-ChIP_TSCs_Mouse1.29341379
73* CEBPB_20176806_ChIP-Seq_MACROPHAGES_Mouse1.29280196
74RUNX2_24764292_ChIP-Seq_MC3T3_Mouse1.29225009
75TAF7L_23326641_ChIP-Seq_C3H10T1-2_Mouse1.29189199
76NCOR1_26117541_ChIP-Seq_K562_Human1.27915718
77* ELK3_25401928_ChIP-Seq_HUVEC_Human1.27596662
78* P300_27058665_Chip-Seq_ZR-75-30cells_Human1.27071059
79STAT3_1855785_ChIP-Seq_MESCs_Mouse1.26540874
80ERG_20887958_ChIP-Seq_HPC-7_Mouse1.26255476
81TCF21_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human1.25651786
82UBF1/2_26484160_Chip-Seq_HMEC-DERIVED_Human1.25018380
83* ZFX_18555785_ChIP-Seq_MESCs_Mouse1.24378635
84ZFP281_18358816_ChIP-ChIP_MESCs_Mouse1.24245589
85ELF3_26769127_Chip-Seq_PDAC-Cell_line_Human1.23286810
86* GATA2_22383799_ChIP-Seq_G1ME_Mouse1.22597274
87HSF1_23293686_ChIP-Seq_STHDH_STRIATAL_Mouse1.21952125
88TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse1.20740225
89TET1_21451524_ChIP-Seq_MESCs_Mouse1.20715691
90RXR_22158963_ChIP-Seq_LIVER_Mouse1.19915194
91E2F4_17652178_ChIP-ChIP_JURKAT_Human1.19593965
92* MYC_18358816_ChIP-ChIP_MESCs_Mouse1.19546390
93TFEB_21752829_ChIP-Seq_HELA_Human1.18069329
94JARID1A_20064375_ChIP-Seq_MESCs_Mouse1.17880049
95CTCF_27219007_Chip-Seq_ERYTHROID_Human1.17770804
96LMO2_20887958_ChIP-Seq_HPC-7_Mouse1.17509675
97NR0B1_18358816_ChIP-ChIP_MESCs_Mouse1.17285781
98* PU_27001747_Chip-Seq_BMDM_Mouse1.16845376
99CCND1_20090754_ChIP-ChIP_RETINA_Mouse1.14886241
100HOXB4_20404135_ChIP-ChIP_EML_Mouse1.13849914
101GFI1B_20887958_ChIP-Seq_HPC-7_Mouse1.13589889
102GATA2_20887958_ChIP-Seq_HPC-7_Mouse1.13545133
103* SA1_27219007_Chip-Seq_ERYTHROID_Human1.13108734
104TFAP2C_20629094_ChIP-Seq_MCF-7_Human1.11145128
105STAT6_21828071_ChIP-Seq_BEAS2B_Human1.10383691
106SRY_22984422_ChIP-ChIP_TESTIS_Rat1.10269526
107P68_20966046_ChIP-Seq_HELA_Human1.09625341
108* CEBPB_21427703_ChIP-Seq_3T3-L1_Mouse1.08951831
109AR_21909140_ChIP-Seq_LNCAP_Human1.08185638
110SMAD4_19686287_ChIP-ChIP_HaCaT_Human1.05856744
111* MYC_19079543_ChIP-ChIP_MESCs_Mouse1.04632985
112SPI1_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse1.04286421
113PPARA_22158963_ChIP-Seq_LIVER_Mouse1.03791804
114E2F1_21310950_ChIP-Seq_MCF-7_Human1.03390835
115PU.1_20176806_ChIP-Seq_MACROPHAGES_Mouse1.02310977
116KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human1.02033539
117* ESR1_17901129_ChIP-ChIP_LIVER_Mouse1.01980974
118GATA1_22025678_ChIP-Seq_K562_Human1.01869553
119* KDM2B_26808549_Chip-Seq_K562_Human1.01630026
120CEBPB_20513432_ChIP-Seq_MACROPHAGES_Mouse1.01627842
121TAL1_20566737_ChIP-Seq_PRIMARY_FETAL_LIVER_ERYTHROID_Mouse1.01515937
122MAF_26560356_Chip-Seq_TH2_Human1.01503004
123* KDM2B_26808549_Chip-Seq_HPB-ALL_Human1.01398631
124CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat1.00970798
125CREB1_20920259_ChIP-Seq_GC1-SPG_Mouse1.00817336
126ELF1_20517297_ChIP-Seq_JURKAT_Human1.00784294
127PU.1_20513432_ChIP-Seq_MACROPHAGES_Mouse1.00127059
128NELFA_20434984_ChIP-Seq_ESCs_Mouse0.99924047
129TCF7_22412390_ChIP-Seq_EML_Mouse0.99829539
130BCOR_27268052_Chip-Seq_Bcells_Human0.97976970
131CDX2_20551321_ChIP-Seq_CACO-2_Human0.97626834
132RARG_19884340_ChIP-ChIP_MEFs_Mouse0.96607575
133* P63_26484246_Chip-Seq_KERATINOCYTES_Human0.96545956
134SMC4_20622854_ChIP-Seq_HELA_Human0.96475716
135CEBPA_20513432_ChIP-Seq_MACROPHAGES_Mouse0.96034022
136* CREB1_26743006_Chip-Seq_LNCaP_Human0.95578837
137FOXP3_17237761_ChIP-ChIP_TREG_Mouse0.95209574
138TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse0.94833886
139ETS1_20019798_ChIP-Seq_JURKAT_Human0.94824936
140LYL1_20887958_ChIP-Seq_HPC-7_Mouse0.94221787
141MYC_19030024_ChIP-ChIP_MESCs_Mouse0.93975205
142* E2F1_18555785_ChIP-Seq_MESCs_Mouse0.93499259
143GATA6_25053715_ChIP-Seq_YYC3_Human0.93065573
144CEBPA_23403033_ChIP-Seq_LIVER_Mouse0.92836072
145* KLF6_26769127_Chip-Seq_PDAC-Cell_line_Human0.92149386
146* GATA4_25053715_ChIP-Seq_YYC3_Human0.90931499
147DCP1A_22483619_ChIP-Seq_HELA_Human0.90587531
148SOX2_27498859_Chip-Seq_STOMACH_Mouse0.90393381
149LXR_22292898_ChIP-Seq_THP-1_Human0.89205899
150GABP_17652178_ChIP-ChIP_JURKAT_Human0.89037384
151HNF4A_19761587_ChIP-ChIP_CACO-2_Human0.88524925
152* RACK7_27058665_Chip-Seq_MCF-7_Human0.87820651

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0001835_abnormal_antigen_presentation3.27763083
2MP0003436_decreased_susceptibility_to3.18064883
3MP0010234_abnormal_vibrissa_follicle3.03848591
4MP0005058_abnormal_lysosome_morphology2.86472210
5MP0005451_abnormal_body_composition2.69483550
6MP0002419_abnormal_innate_immunity2.66718531
7MP0009785_altered_susceptibility_to2.65518465
8MP0009840_abnormal_foam_cell2.61728984
9MP0005025_abnormal_response_to2.45351668
10MP0003303_peritoneal_inflammation2.37211851
11MP0002877_abnormal_melanocyte_morpholog2.35052740
12MP0002148_abnormal_hypersensitivity_rea2.28296835
13MP0003693_abnormal_embryo_hatching2.22754504
14MP0005464_abnormal_platelet_physiology2.16722849
15MP0005000_abnormal_immune_tolerance2.13270885
16MP0002452_abnormal_antigen_presenting2.10871055
17MP0008438_abnormal_cutaneous_collagen2.09796900
18MP0002396_abnormal_hematopoietic_system2.06168339
19MP0010155_abnormal_intestine_physiology2.02795320
20MP0002796_impaired_skin_barrier2.02645284
21MP0000685_abnormal_immune_system2.00140446
22MP0000490_abnormal_crypts_of1.99444617
23MP0001790_abnormal_immune_system1.98183487
24MP0005387_immune_system_phenotype1.98183487
25MP0009333_abnormal_splenocyte_physiolog1.97963901
26MP0003724_increased_susceptibility_to1.94933047
27MP0003300_gastrointestinal_ulcer1.93106085
28MP0003453_abnormal_keratinocyte_physiol1.91648032
29MP0006082_CNS_inflammation1.90149072
30MP0002723_abnormal_immune_serum1.88774841
31MP0001800_abnormal_humoral_immune1.87986503
32MP0001819_abnormal_immune_cell1.86181351
33MP0001533_abnormal_skeleton_physiology1.85556990
34MP0001873_stomach_inflammation1.85556404
35MP0003191_abnormal_cellular_cholesterol1.85248867
36MP0002420_abnormal_adaptive_immunity1.84140821
37MP0003806_abnormal_nucleotide_metabolis1.82702030
38MP0003183_abnormal_peptide_metabolism1.80866945
39MP0005671_abnormal_response_to1.73340694
40MP0003172_abnormal_lysosome_physiology1.72037951
41MP0001845_abnormal_inflammatory_respons1.70148445
42MP0001849_ear_inflammation1.66508901
43MP0002139_abnormal_hepatobiliary_system1.64195370
44MP0000465_gastrointestinal_hemorrhage1.57898079
45MP0000678_abnormal_parathyroid_gland1.55507821
46MP0002166_altered_tumor_susceptibility1.54123333
47MP0008469_abnormal_protein_level1.53407776
48MP0005501_abnormal_skin_physiology1.53052932
49MP0009278_abnormal_bone_marrow1.52826376
50MP0004947_skin_inflammation1.52428927
51MP0002405_respiratory_system_inflammati1.51353712
52MP0000858_altered_metastatic_potential1.49303860
53MP0001545_abnormal_hematopoietic_system1.47549700
54MP0005397_hematopoietic_system_phenotyp1.47549700
55MP0000716_abnormal_immune_system1.47440691
56MP0005174_abnormal_tail_pigmentation1.43826159
57MP0002006_tumorigenesis1.43280572
58MP0005409_darkened_coat_color1.42364535
59MP0002398_abnormal_bone_marrow1.41235660
60MP0000343_altered_response_to1.39801132
61MP0004185_abnormal_adipocyte_glucose1.37444012
62MP0010352_gastrointestinal_tract_polyps1.37047419
63MP0005310_abnormal_salivary_gland1.36151123
64MP0003866_abnormal_defecation1.34306860
65MP0004264_abnormal_extraembryonic_tissu1.33733580
66MP0002429_abnormal_blood_cell1.33665438
67MP0004782_abnormal_surfactant_physiolog1.33414613
68MP0009764_decreased_sensitivity_to1.33208919
69MP0004858_abnormal_nervous_system1.32661418
70MP0000689_abnormal_spleen_morphology1.32477281
71MP0001853_heart_inflammation1.32368692
72MP0010307_abnormal_tumor_latency1.31624807
73MP0003448_altered_tumor_morphology1.29340734
74MP0006054_spinal_hemorrhage1.29255959
75MP0003566_abnormal_cell_adhesion1.26460238
76MP0002722_abnormal_immune_system1.24496230
77MP0002060_abnormal_skin_morphology1.23068741
78MP0005257_abnormal_intraocular_pressure1.22486252
79MP0008004_abnormal_stomach_pH1.21155078
80MP0003091_abnormal_cell_migration1.19873070
81MP0001666_abnormal_nutrient_absorption1.16713276
82MP0003111_abnormal_nucleus_morphology1.16116073
83MP0001216_abnormal_epidermal_layer1.13322333
84MP0003186_abnormal_redox_activity1.12441025
85MP0001663_abnormal_digestive_system1.08476222
86MP0005076_abnormal_cell_differentiation1.08422846
87MP0004233_abnormal_muscle_weight1.07586345
88MP0003075_altered_response_to1.06174803
89MP0004808_abnormal_hematopoietic_stem1.03441817
90MP0003828_pulmonary_edema1.00992241
91MP0004272_abnormal_basement_membrane0.99362587
92MP0008260_abnormal_autophagy0.98768314
93MP0002998_abnormal_bone_remodeling0.97378736
94MP0008007_abnormal_cellular_replicative0.97341449
95MP0003763_abnormal_thymus_physiology0.96844866
96MP0001730_embryonic_growth_arrest0.93981335
97MP0005365_abnormal_bile_salt0.92888083
98MP0005166_decreased_susceptibility_to0.91520502
99MP0005666_abnormal_adipose_tissue0.91023756
100MP0000477_abnormal_intestine_morphology0.89384971
101MP0002132_abnormal_respiratory_system0.89071750
102MP0005165_increased_susceptibility_to0.86952741
103MP0003705_abnormal_hypodermis_morpholog0.85236207
104MP0005390_skeleton_phenotype0.85220770
105MP0001958_emphysema0.84725168
106MP0002019_abnormal_tumor_incidence0.84313290
107MP0005023_abnormal_wound_healing0.84088414
108MP0001851_eye_inflammation0.84071692
109MP0005319_abnormal_enzyme/_coenzyme0.83532967
110MP0009643_abnormal_urine_homeostasis0.83310953
111MP0002277_abnormal_respiratory_mucosa0.83240883
112MP0000467_abnormal_esophagus_morphology0.83057227
113MP0000569_abnormal_digit_pigmentation0.82531340
114MP0005360_urolithiasis0.82461542
115MP0003077_abnormal_cell_cycle0.81991811
116MP0004957_abnormal_blastocyst_morpholog0.81473458
117MP0009931_abnormal_skin_appearance0.80994944
118MP0002136_abnormal_kidney_physiology0.80823768
119MP0000371_diluted_coat_color0.80820792
120MP0001881_abnormal_mammary_gland0.80782375
121MP0002933_joint_inflammation0.80732675
122MP0005621_abnormal_cell_physiology0.79235037
123MP0000537_abnormal_urethra_morphology0.76951208
124MP0002098_abnormal_vibrissa_morphology0.76840794
125MP0000598_abnormal_liver_morphology0.76517535
126MP0009763_increased_sensitivity_to0.75891518
127MP0003279_aneurysm0.75804676
128MP0000249_abnormal_blood_vessel0.75475827
129MP0000609_abnormal_liver_physiology0.75283372
130MP0003941_abnormal_skin_development0.74691818
131MP0005381_digestive/alimentary_phenotyp0.74486787
132MP0000681_abnormal_thyroid_gland0.74338786
133MP0003656_abnormal_erythrocyte_physiolo0.74260179
134MP0010368_abnormal_lymphatic_system0.73949317
135MP0002896_abnormal_bone_mineralization0.73079731
136MP0002254_reproductive_system_inflammat0.72856781
137MP0000767_abnormal_smooth_muscle0.71603821
138MP0005083_abnormal_biliary_tract0.69741985
139MP0000703_abnormal_thymus_morphology0.65751772

Predicted human phenotypes

RankGene SetZ-score
1Recurrent abscess formation (HP:0002722)5.57843687
2Eczematoid dermatitis (HP:0000976)5.33659770
3Recurrent bacterial skin infections (HP:0005406)5.06054743
4Vacuolated lymphocytes (HP:0001922)4.57898230
5Recurrent gram-negative bacterial infections (HP:0005420)4.26477918
6Abnormality of macrophages (HP:0004311)4.06202913
7Systemic lupus erythematosus (HP:0002725)3.96159540
8Elevated erythrocyte sedimentation rate (HP:0003565)3.56976589
9Myositis (HP:0100614)3.49112029
10Pustule (HP:0200039)3.43238838
11Vertebral compression fractures (HP:0002953)3.40251420
12Abnormality of glycosphingolipid metabolism (HP:0004343)3.31186990
13Abnormality of glycolipid metabolism (HP:0010969)3.31186990
14Abnormality of liposaccharide metabolism (HP:0010968)3.31186990
15Recurrent fungal infections (HP:0002841)3.28208970
16Thrombocytosis (HP:0001894)3.25219977
17Dysostosis multiplex (HP:0000943)3.24448188
18Chronic obstructive pulmonary disease (HP:0006510)3.21064982
19Obstructive lung disease (HP:0006536)3.21064982
20Increased cerebral lipofuscin (HP:0011813)3.16308716
21Premature rupture of membranes (HP:0001788)3.15763824
22Recurrent skin infections (HP:0001581)3.13021350
23Gingivitis (HP:0000230)3.12523961
24Thin bony cortex (HP:0002753)2.99225263
25Mucopolysacchariduria (HP:0008155)2.95740849
26Urinary glycosaminoglycan excretion (HP:0003541)2.95740849
27Petechiae (HP:0000967)2.95472144
28Orchitis (HP:0100796)2.94183903
29Autoimmune thrombocytopenia (HP:0001973)2.90881955
30Protrusio acetabuli (HP:0003179)2.86545511
31Abnormality of mucopolysaccharide metabolism (HP:0011020)2.86327625
32Abnormality of polysaccharide metabolism (HP:0011012)2.86327625
33Abnormality of glycosaminoglycan metabolism (HP:0004371)2.86327625
34Periodontitis (HP:0000704)2.85702554
35Chronic otitis media (HP:0000389)2.82735575
36Increased neuronal autofluorescent lipopigment (HP:0002074)2.82593422
37Interstitial pulmonary disease (HP:0006530)2.81760316
38Flat acetabular roof (HP:0003180)2.81439231
39Mediastinal lymphadenopathy (HP:0100721)2.78669299
40Cheilitis (HP:0100825)2.73285170
41Abnormality of the distal phalanges of the toes (HP:0010182)2.72757061
42Recurrent viral infections (HP:0004429)2.71644609
43Malnutrition (HP:0004395)2.61293407
44IgM deficiency (HP:0002850)2.58576577
45Glomerulonephritis (HP:0000099)2.57669950
46Thoracic kyphosis (HP:0002942)2.56981964
47Spontaneous hematomas (HP:0007420)2.55101914
48Urticaria (HP:0001025)2.45048577
49Distal upper limb amyotrophy (HP:0007149)2.39281816
50Upper limb amyotrophy (HP:0009129)2.39281816
51Abnormality of T cell physiology (HP:0011840)2.39269393
52Poor head control (HP:0002421)2.37920481
53Cellulitis (HP:0100658)2.37501024
54Distal lower limb muscle weakness (HP:0009053)2.34710937
55Agnosia (HP:0010524)2.31906419
56Abnormality of monocarboxylic acid metabolism (HP:0010996)2.28990318
57Retrobulbar optic neuritis (HP:0100654)2.27380281
58Optic neuritis (HP:0100653)2.27380281
59Achilles tendon contracture (HP:0001771)2.26548072
60Meningitis (HP:0001287)2.25871997
61Reduced antithrombin III activity (HP:0001976)2.24797298
62Abnormality of the thoracic spine (HP:0100711)2.23882069
63Prostate neoplasm (HP:0100787)2.22272487
64Vasculitis (HP:0002633)2.22100416
65Osteomyelitis (HP:0002754)2.21383750
66Recurrent cutaneous fungal infections (HP:0011370)2.21259218
67Chronic mucocutaneous candidiasis (HP:0002728)2.21259218
68Abnormality of the prostate (HP:0008775)2.19940647
69Basal ganglia calcification (HP:0002135)2.19881214
70Upper motor neuron abnormality (HP:0002127)2.19863100
71Cervical subluxation (HP:0003308)2.15181554
72Osteolytic defects of the phalanges of the hand (HP:0009771)2.13733713
73Osteolytic defects of the hand bones (HP:0009699)2.13733713
74Abnormality of the lumbar spine (HP:0100712)2.13690018
75Abnormal delayed hypersensitivity skin test (HP:0002963)2.13041171
76Hemorrhage of the eye (HP:0011885)2.12283145
77Abnormal platelet function (HP:0011869)2.11533912
78Impaired platelet aggregation (HP:0003540)2.11533912
79Short nail (HP:0001799)2.10229999
80Hyperparathyroidism (HP:0000843)2.10080726
81Aplastic anemia (HP:0001915)2.09320032
82Abnormality of the Achilles tendon (HP:0005109)2.09028442
83Distal lower limb amyotrophy (HP:0008944)2.08484224
84Albinism (HP:0001022)2.07658890
85Primitive reflexes (palmomental, snout, glabellar) (HP:0002476)2.07139149
86Cerebral aneurysm (HP:0004944)2.06394813
87Gastrointestinal inflammation (HP:0004386)2.06168744
88Inflammation of the large intestine (HP:0002037)2.05418874
89Increased connective tissue (HP:0009025)2.04740964
90Trismus (HP:0000211)2.03136545
91Hepatosplenomegaly (HP:0001433)2.02371077
92Abnormality of complement system (HP:0005339)2.01663442
93Gingival bleeding (HP:0000225)1.99847772
94Hand muscle atrophy (HP:0009130)1.97457391
95Abnormality of the nasal mucosa (HP:0000433)1.97354311
96Prolonged bleeding time (HP:0003010)1.97326441
97Disinhibition (HP:0000734)1.97325524
98Broad face (HP:0000283)1.96979487
99Granulocytopenia (HP:0001913)1.96726679
100Leukocytosis (HP:0001974)1.96554931
101Hyperacusis (HP:0010780)1.96311308
102Fragile skin (HP:0001030)1.95361924
103Recurrent pneumonia (HP:0006532)1.94181390
104Epistaxis (HP:0000421)1.93735161
105Pulmonary infiltrates (HP:0002113)1.93621662
106Increased IgE level (HP:0003212)1.93308597
107Arterial thrombosis (HP:0004420)1.93162202
108Skin ulcer (HP:0200042)1.92744630
109Axonal loss (HP:0003447)1.92122442
110J-shaped sella turcica (HP:0002680)1.91419946
111Abdominal distention (HP:0003270)1.90265229
112Eosinophilia (HP:0001880)1.88533580
113Elevated alkaline phosphatase (HP:0003155)1.88512811
114Joint hemorrhage (HP:0005261)1.88329202
115Disproportionate tall stature (HP:0001519)1.88118408
116Hemoptysis (HP:0002105)1.86856549
117Polygenic inheritance (HP:0010982)1.86299467
118Anorexia (HP:0002039)1.86052307
119Cholecystitis (HP:0001082)1.85745919
120Abnormal gallbladder physiology (HP:0012438)1.85745919
121Blue sclerae (HP:0000592)1.85440859
122Myocardial infarction (HP:0001658)1.85042277
123Chest pain (HP:0100749)1.84893651
124Atrophic scars (HP:0001075)1.81155932
125Ankyloglossia (HP:0010296)1.80745885
126Purpura (HP:0000979)1.79883847
127Abnormality of alkaline phosphatase activity (HP:0004379)1.79829128
128Nephritis (HP:0000123)1.79254086
129Pathologic fracture (HP:0002756)1.79185244
130Loss of speech (HP:0002371)1.78691080
131Abnormal enzyme/coenzyme activity (HP:0012379)1.77520404
132Esophageal varix (HP:0002040)1.76808164
133Amyloidosis (HP:0011034)1.76796783
134Abnormality of T cells (HP:0002843)1.76685021
135Nasal polyposis (HP:0100582)1.76524906
136Abnormality of the acetabulum (HP:0003170)1.74376697
137Increased serum ferritin (HP:0003281)1.74202696
138Hypertensive crisis (HP:0100735)1.73683689
139Dilatation of the ascending aorta (HP:0005111)1.72677936
140Ulnar bowing (HP:0003031)1.72182866
141Centrally nucleated skeletal muscle fibers (HP:0003687)1.71278216
142Chromosomal breakage induced by crosslinking agents (HP:0003221)1.70997651
143Recurrent lower respiratory tract infections (HP:0002783)1.70954977
144Polycythemia (HP:0001901)1.70243545
145Bone pain (HP:0002653)1.69678691
146Nausea (HP:0002018)1.68831229
147Abnormality of oral frenula (HP:0000190)1.68709515
148Stridor (HP:0010307)1.68554750
149Hematochezia (HP:0002573)1.67146190
150Encephalitis (HP:0002383)1.66855429
151Progressive neurologic deterioration (HP:0002344)1.66297581
152Colitis (HP:0002583)1.65921227
153Ragged-red muscle fibers (HP:0003200)1.65856752
154Poikiloderma (HP:0001029)1.65596154
155Abnormal trabecular bone morphology (HP:0100671)1.65203867
156Nuclear cataract (HP:0100018)1.64089893
157Atelectasis (HP:0100750)1.63664439
158Right ventricular cardiomyopathy (HP:0011663)1.63312191
159Generalized amyotrophy (HP:0003700)1.63032971
160Prolonged neonatal jaundice (HP:0006579)1.62975726
161Aneurysm (HP:0002617)1.62589162
162Long palpebral fissure (HP:0000637)1.62324423
163Ankle contracture (HP:0006466)1.61360310
164Abnormality of carpal bone ossification (HP:0006257)1.60748836

Predicted kinase interactions (KEA)

RankGene SetZ-score
1IRAK33.55709612
2SMG13.37581231
3ERN13.18794494
4IRAK42.89219010
5BLK2.83961558
6MAP4K12.77485384
7PRPF4B2.37698437
8TYK22.28661055
9EPHA22.22639565
10TBK12.17690180
11SIK12.17558949
12TAOK32.06018622
13ICK2.04337563
14PIM21.96559811
15MAP3K141.90977609
16CDK121.89368161
17KIT1.80389720
18MAP2K31.74260034
19NME21.74108047
20ZAP701.72609240
21PAK41.70291976
22JAK31.69301296
23BTK1.67647090
24BUB11.64110961
25STK161.63638268
26TESK11.63341203
27STK101.62938815
28EIF2AK11.57364352
29TEC1.54864581
30TESK21.52247873
31MAP3K31.50205770
32MAP3K111.49296768
33KSR21.49178036
34IKBKE1.41700182
35EEF2K1.40376087
36CSF1R1.37401243
37PTK61.36915495
38MAP2K21.33350337
39TRIB31.30618605
40MAP3K131.28075823
41IKBKB1.25756751
42EIF2AK31.25080213
43PDGFRA1.22025007
44TGFBR21.21481257
45RPS6KA41.21408835
46PRKG21.20400967
47KDR1.18575035
48ARAF1.16589840
49EPHB11.15292009
50FGFR41.13527525
51NEK21.12529937
52SCYL21.12379320
53MET1.10825763
54TAOK11.10041726
55MAP3K11.09176894
56TXK1.08911456
57RIPK41.08422429
58MAP3K21.07234246
59WEE11.04105240
60PTK21.04003416
61LMTK20.98760396
62CAMKK20.98568890
63MST1R0.92696362
64JAK10.91684761
65PRKD20.91355780
66FRK0.90999647
67BCKDK0.90813606
68NEK90.90449540
69LRRK20.89961768
70PKN20.89257300
71CDC42BPA0.88810329
72CSK0.88028719
73MATK0.87179886
74RPS6KB20.86683676
75FES0.86523965
76MAP3K100.84336327
77MAP3K80.83252762
78PDPK10.82334414
79HCK0.81791736
80PBK0.81722648
81LYN0.81297540
82SYK0.80832416
83TAOK20.79258195
84PIM10.78385764
85RIPK10.77080057
86SIK30.76416745
87BRAF0.76273984
88LATS20.76263864
89CAMK1D0.76202850
90TTK0.75264232
91JAK20.74472382
92AKT30.72233318
93PLK40.72040652
94CLK10.71265880
95MTOR0.70194088
96IRAK20.69529523
97FLT30.68660015
98CHUK0.66281964
99DDR20.66158656
100GRK60.63670899
101BRSK20.63369182
102CDK60.62833610
103STK240.61352482
104MAP3K60.61285774
105LCK0.61018408
106CDK70.59624597
107EIF2AK20.58565848
108PRKD30.56959621
109CDK40.56504851
110FGR0.54448719
111RPS6KA60.52572887
112ACVR1B0.52518137
113ITK0.50504028
114YES10.49677072
115MST40.47764469
116ABL20.47694237
117MARK20.47657980
118TRPM70.47648412
119TSSK60.47573034
120NEK10.47477166
121PRKCD0.46884551
122MAP3K120.46700521
123ATR0.45597651
124BMX0.45542100
125TTN0.45514676
126RPS6KL10.45492249
127RPS6KC10.45492249
128MARK30.45373997
129MAPK110.45272028
130MAPK40.45219626
131MELK0.44587895
132STK40.43952064
133NUAK10.42976649
134RPS6KA20.42870995
135PAK10.42229285
136MAPKAPK20.41242858
137AURKB0.40865880
138CDK80.40047576
139MOS0.40013248
140ILK0.39538414
141ZAK0.39047959
142MAPKAPK30.38883089
143STK380.38820178
144PDGFRB0.37576245
145CDK90.33631885
146AURKA0.32297215

Predicted pathways (KEGG)

RankGene SetZ-score
1Other glycan degradation_Homo sapiens_hsa005113.10319795
2Leishmaniasis_Homo sapiens_hsa051402.79293282
3Staphylococcus aureus infection_Homo sapiens_hsa051502.54891928
4Glycosaminoglycan degradation_Homo sapiens_hsa005312.53132860
5Lysosome_Homo sapiens_hsa041422.29775380
6DNA replication_Homo sapiens_hsa030302.26874681
7Legionellosis_Homo sapiens_hsa051342.12945044
8Cytosolic DNA-sensing pathway_Homo sapiens_hsa046232.00672232
9Toll-like receptor signaling pathway_Homo sapiens_hsa046201.94540439
10Cyanoamino acid metabolism_Homo sapiens_hsa004601.94187997
11Pertussis_Homo sapiens_hsa051331.91069291
12Osteoclast differentiation_Homo sapiens_hsa043801.78123577
13Bladder cancer_Homo sapiens_hsa052191.75293593
14Citrate cycle (TCA cycle)_Homo sapiens_hsa000201.70491446
15NF-kappa B signaling pathway_Homo sapiens_hsa040641.68344664
16Butirosin and neomycin biosynthesis_Homo sapiens_hsa005241.66093720
17RIG-I-like receptor signaling pathway_Homo sapiens_hsa046221.58972003
18Antigen processing and presentation_Homo sapiens_hsa046121.58037188
19Measles_Homo sapiens_hsa051621.55782270
20Intestinal immune network for IgA production_Homo sapiens_hsa046721.55380556
21Pentose phosphate pathway_Homo sapiens_hsa000301.51721753
22Tuberculosis_Homo sapiens_hsa051521.51625490
23NOD-like receptor signaling pathway_Homo sapiens_hsa046211.51051034
24Vitamin digestion and absorption_Homo sapiens_hsa049771.48829581
25Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005201.48443286
26Influenza A_Homo sapiens_hsa051641.45702007
27Central carbon metabolism in cancer_Homo sapiens_hsa052301.44438754
28Shigellosis_Homo sapiens_hsa051311.44165080
29Apoptosis_Homo sapiens_hsa042101.43894045
30Pathogenic Escherichia coli infection_Homo sapiens_hsa051301.34423106
31Herpes simplex infection_Homo sapiens_hsa051681.32512142
32Base excision repair_Homo sapiens_hsa034101.31927657
33Mismatch repair_Homo sapiens_hsa034301.28015706
34Proteasome_Homo sapiens_hsa030501.27339493
35Toxoplasmosis_Homo sapiens_hsa051451.25640703
36Inflammatory bowel disease (IBD)_Homo sapiens_hsa053211.24890280
37Leukocyte transendothelial migration_Homo sapiens_hsa046701.24085284
38Renin-angiotensin system_Homo sapiens_hsa046141.23952663
39Prion diseases_Homo sapiens_hsa050201.22566287
40B cell receptor signaling pathway_Homo sapiens_hsa046621.22201740
41Pentose and glucuronate interconversions_Homo sapiens_hsa000401.21314931
42TNF signaling pathway_Homo sapiens_hsa046681.18741297
43Salmonella infection_Homo sapiens_hsa051321.17735187
44Folate biosynthesis_Homo sapiens_hsa007901.15385089
45Malaria_Homo sapiens_hsa051441.13347904
46Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046661.12244707
47Phagosome_Homo sapiens_hsa041451.11661194
48Caffeine metabolism_Homo sapiens_hsa002321.09970132
49N-Glycan biosynthesis_Homo sapiens_hsa005101.09449792
50Biosynthesis of amino acids_Homo sapiens_hsa012301.09213974
51Thyroid cancer_Homo sapiens_hsa052161.08716124
52Non-small cell lung cancer_Homo sapiens_hsa052231.07951296
53Hematopoietic cell lineage_Homo sapiens_hsa046401.07864864
54Notch signaling pathway_Homo sapiens_hsa043301.07140992
55Vibrio cholerae infection_Homo sapiens_hsa051101.01815028
56Hepatitis C_Homo sapiens_hsa051601.01106990
57Chagas disease (American trypanosomiasis)_Homo sapiens_hsa051421.00777140
58Carbon metabolism_Homo sapiens_hsa012001.00258785
59Bacterial invasion of epithelial cells_Homo sapiens_hsa051000.97380010
60VEGF signaling pathway_Homo sapiens_hsa043700.96423061
61Homologous recombination_Homo sapiens_hsa034400.96023876
62Fat digestion and absorption_Homo sapiens_hsa049750.95054737
63Hepatitis B_Homo sapiens_hsa051610.94343266
64Galactose metabolism_Homo sapiens_hsa000520.93411848
65Acute myeloid leukemia_Homo sapiens_hsa052210.92735985
66One carbon pool by folate_Homo sapiens_hsa006700.92676613
67Phenylalanine metabolism_Homo sapiens_hsa003600.90905766
68Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.85994064
69Asthma_Homo sapiens_hsa053100.83890862
70Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.83016861
71Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046500.82821757
72Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.82608823
73Drug metabolism - other enzymes_Homo sapiens_hsa009830.81649799
74Glutathione metabolism_Homo sapiens_hsa004800.81621892
752-Oxocarboxylic acid metabolism_Homo sapiens_hsa012100.80693432
76Pyrimidine metabolism_Homo sapiens_hsa002400.80145399
77Sulfur relay system_Homo sapiens_hsa041220.79598769
78Fc epsilon RI signaling pathway_Homo sapiens_hsa046640.77389138
79Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005320.77232192
80Fructose and mannose metabolism_Homo sapiens_hsa000510.76155892
81Primary immunodeficiency_Homo sapiens_hsa053400.75989571
82Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.74615097
83Proteoglycans in cancer_Homo sapiens_hsa052050.72887667
84Jak-STAT signaling pathway_Homo sapiens_hsa046300.72819244
85Endocytosis_Homo sapiens_hsa041440.72724036
86Renal cell carcinoma_Homo sapiens_hsa052110.71995457
87Chemokine signaling pathway_Homo sapiens_hsa040620.71707007
88Histidine metabolism_Homo sapiens_hsa003400.71528185
89Arachidonic acid metabolism_Homo sapiens_hsa005900.71377928
90Rheumatoid arthritis_Homo sapiens_hsa053230.70402784
91Chronic myeloid leukemia_Homo sapiens_hsa052200.70381063
92Sulfur metabolism_Homo sapiens_hsa009200.69749982
93Mineral absorption_Homo sapiens_hsa049780.69541405
94Epstein-Barr virus infection_Homo sapiens_hsa051690.67678491
95Ribosome_Homo sapiens_hsa030100.67415680
96HTLV-I infection_Homo sapiens_hsa051660.66046317
97Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.66034569
98Ascorbate and aldarate metabolism_Homo sapiens_hsa000530.65104390
99Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004000.64875977
100Arginine biosynthesis_Homo sapiens_hsa002200.64258952
101Cytokine-cytokine receptor interaction_Homo sapiens_hsa040600.63990259
102p53 signaling pathway_Homo sapiens_hsa041150.60584777
103Sphingolipid signaling pathway_Homo sapiens_hsa040710.60464353
104Sphingolipid metabolism_Homo sapiens_hsa006000.60084432
105AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049330.59659641
106mTOR signaling pathway_Homo sapiens_hsa041500.58438584
107Cell cycle_Homo sapiens_hsa041100.58417565
108Endometrial cancer_Homo sapiens_hsa052130.58306412
109Graft-versus-host disease_Homo sapiens_hsa053320.57429325
110Insulin signaling pathway_Homo sapiens_hsa049100.57076787
111Small cell lung cancer_Homo sapiens_hsa052220.56693747
112Focal adhesion_Homo sapiens_hsa045100.56571537
113Pancreatic cancer_Homo sapiens_hsa052120.53846650
114Starch and sucrose metabolism_Homo sapiens_hsa005000.53377268
115Complement and coagulation cascades_Homo sapiens_hsa046100.53290427
116Allograft rejection_Homo sapiens_hsa053300.52820909
117Adipocytokine signaling pathway_Homo sapiens_hsa049200.52515314
118Insulin resistance_Homo sapiens_hsa049310.52389232
119Prostate cancer_Homo sapiens_hsa052150.50942332
120Viral carcinogenesis_Homo sapiens_hsa052030.50380852
121Neurotrophin signaling pathway_Homo sapiens_hsa047220.49165450
122Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.48807166
123Adherens junction_Homo sapiens_hsa045200.46980912
124Spliceosome_Homo sapiens_hsa030400.45763021
125African trypanosomiasis_Homo sapiens_hsa051430.44373862
126HIF-1 signaling pathway_Homo sapiens_hsa040660.44267902
127Viral myocarditis_Homo sapiens_hsa054160.42618313
128Platelet activation_Homo sapiens_hsa046110.41996832
129Regulation of actin cytoskeleton_Homo sapiens_hsa048100.41438775
130Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030080.40935569
131beta-Alanine metabolism_Homo sapiens_hsa004100.40591238
132Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.40568809
133Transcriptional misregulation in cancer_Homo sapiens_hsa052020.40542407
134Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009700.39828548
135Tyrosine metabolism_Homo sapiens_hsa003500.38642715
136Amoebiasis_Homo sapiens_hsa051460.38080778
137Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049610.36246805

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