RNASEK

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1mitochondrial electron transport, NADH to ubiquinone (GO:0006120)5.57468374
2mitochondrial ATP synthesis coupled proton transport (GO:0042776)4.77149449
3energy coupled proton transport, down electrochemical gradient (GO:0015985)4.70141753
4ATP synthesis coupled proton transport (GO:0015986)4.70141753
5respiratory electron transport chain (GO:0022904)4.67528866
6electron transport chain (GO:0022900)4.58750661
7energy coupled proton transmembrane transport, against electrochemical gradient (GO:0015988)4.41695296
8ATP hydrolysis coupled proton transport (GO:0015991)4.41695296
9transferrin transport (GO:0033572)4.10825570
10chaperone-mediated protein transport (GO:0072321)4.07349080
11protein neddylation (GO:0045116)3.97079822
12positive regulation of insulin secretion involved in cellular response to glucose stimulus (GO:003573.81795837
13ferric iron transport (GO:0015682)3.80292671
14trivalent inorganic cation transport (GO:0072512)3.80292671
15synaptic vesicle exocytosis (GO:0016079)3.73820039
16hydrogen ion transmembrane transport (GO:1902600)3.62616182
17phagosome maturation (GO:0090382)3.60526103
18platelet dense granule organization (GO:0060155)3.60283221
19dopamine biosynthetic process (GO:0042416)3.53494190
20protein complex biogenesis (GO:0070271)3.38725728
21neuronal action potential propagation (GO:0019227)3.35379855
22neuron cell-cell adhesion (GO:0007158)3.34819052
23deoxyribonucleoside monophosphate metabolic process (GO:0009162)3.33437093
24proton transport (GO:0015992)3.28809940
25signal peptide processing (GO:0006465)3.24201930
26hydrogen transport (GO:0006818)3.22940353
27neutrophil activation involved in immune response (GO:0002283)3.19573485
28protein maturation by protein folding (GO:0022417)3.18750992
29fatty acid elongation (GO:0030497)3.15494006
30regulation of catecholamine metabolic process (GO:0042069)3.05579232
31regulation of dopamine metabolic process (GO:0042053)3.05579232
32L-phenylalanine catabolic process (GO:0006559)3.00621918
33erythrose 4-phosphate/phosphoenolpyruvate family amino acid catabolic process (GO:1902222)3.00621918
34calcium-mediated signaling using intracellular calcium source (GO:0035584)2.98099739
35L-phenylalanine metabolic process (GO:0006558)2.97564173
36erythrose 4-phosphate/phosphoenolpyruvate family amino acid metabolic process (GO:1902221)2.97564173
37DNA deamination (GO:0045006)2.92237902
38axon ensheathment in central nervous system (GO:0032291)2.91432591
39central nervous system myelination (GO:0022010)2.91432591
40positive regulation of calcium ion-dependent exocytosis (GO:0045956)2.89341073
41regulation of oxidative phosphorylation (GO:0002082)2.88649091
42mitochondrial respiratory chain complex assembly (GO:0033108)2.87332291
43mitochondrial respiratory chain complex I assembly (GO:0032981)2.87209274
44NADH dehydrogenase complex assembly (GO:0010257)2.87209274
45mitochondrial respiratory chain complex I biogenesis (GO:0097031)2.87209274
46glutamate secretion (GO:0014047)2.86318335
47long-chain fatty acid biosynthetic process (GO:0042759)2.85990497
48negative regulation of endoplasmic reticulum calcium ion concentration (GO:0032471)2.84992046
49regulation of mitochondrial translation (GO:0070129)2.83761038
50GDP-mannose metabolic process (GO:0019673)2.81696222
51neuromuscular process controlling posture (GO:0050884)2.77289263
52amino sugar catabolic process (GO:0046348)2.77152624
53xenobiotic catabolic process (GO:0042178)2.74494061
54negative regulation of calcium ion transport into cytosol (GO:0010523)2.74095811
55negative regulation of inflammatory response to antigenic stimulus (GO:0002862)2.73478336
56regulation of synaptic vesicle exocytosis (GO:2000300)2.73190779
57amyloid precursor protein catabolic process (GO:0042987)2.71676802
58ATP biosynthetic process (GO:0006754)2.71411120
59glycerophospholipid catabolic process (GO:0046475)2.69701181
60C-terminal protein lipidation (GO:0006501)2.69355965
61dopamine transport (GO:0015872)2.68663124
62regulation of autophagic vacuole assembly (GO:2000785)2.67389752
63synaptic vesicle maturation (GO:0016188)2.62687742
64viral protein processing (GO:0019082)2.62091719
65substantia nigra development (GO:0021762)2.59624525
66detection of temperature stimulus (GO:0016048)2.59088872
67regulation of short-term neuronal synaptic plasticity (GO:0048172)2.58774850
68inner mitochondrial membrane organization (GO:0007007)2.58564584
69regulation of amyloid precursor protein catabolic process (GO:1902991)2.58127967
70synaptic transmission, dopaminergic (GO:0001963)2.57441723
71negative regulation of cation channel activity (GO:2001258)2.54283521
72negative regulation of ryanodine-sensitive calcium-release channel activity (GO:0060315)2.53016690
73purine ribonucleoside triphosphate biosynthetic process (GO:0009206)2.52026536
74negative regulation of neurotransmitter transport (GO:0051589)2.51941533
75immunoglobulin mediated immune response (GO:0016064)2.50808298
76cellular response to zinc ion (GO:0071294)2.49771895
77sequestering of actin monomers (GO:0042989)2.49514085
78purine nucleoside triphosphate biosynthetic process (GO:0009145)2.48076367
79response to interferon-beta (GO:0035456)2.47747964
80eosinophil migration (GO:0072677)2.47550007
81regulation of synaptic vesicle transport (GO:1902803)2.46830154
82positive regulation of lymphocyte apoptotic process (GO:0070230)2.45719267
83regulation of vesicle fusion (GO:0031338)2.45387977
84response to redox state (GO:0051775)2.45088706
85GTP biosynthetic process (GO:0006183)2.44955747
86detection of temperature stimulus involved in sensory perception (GO:0050961)2.44903103
87detection of temperature stimulus involved in sensory perception of pain (GO:0050965)2.44903103
88positive regulation of prostaglandin secretion (GO:0032308)2.44734871
89response to cocaine (GO:0042220)2.43673994
90iron ion transport (GO:0006826)2.43021521
91catecholamine biosynthetic process (GO:0042423)2.42606348
92catechol-containing compound biosynthetic process (GO:0009713)2.42606348
93peptide hormone processing (GO:0016486)2.42507103
94hydrogen peroxide catabolic process (GO:0042744)2.41871979
95autophagic vacuole fusion (GO:0000046)2.41760097
96phosphorylated carbohydrate dephosphorylation (GO:0046838)2.41674835
97inositol phosphate dephosphorylation (GO:0046855)2.41674835
98mitochondrial fragmentation involved in apoptotic process (GO:0043653)2.41319477
99granulocyte activation (GO:0036230)2.38316827
100potassium ion export (GO:0071435)2.37028754
101detection of calcium ion (GO:0005513)2.36681005
102neutrophil activation (GO:0042119)2.35955203
103establishment of protein localization to mitochondrial membrane (GO:0090151)2.35807268
104presynaptic membrane organization (GO:0097090)2.35224394
105regulation of dopamine secretion (GO:0014059)2.34088277
106nitric oxide biosynthetic process (GO:0006809)2.33909251
107negative regulation of synaptic transmission, GABAergic (GO:0032229)2.33325747
108inositol phosphate catabolic process (GO:0071545)2.33325076
109cytochrome complex assembly (GO:0017004)2.33166644
110presynaptic membrane assembly (GO:0097105)2.32749935
111eosinophil chemotaxis (GO:0048245)2.32660105
112lipoxygenase pathway (GO:0019372)2.32366145
113glucosamine-containing compound catabolic process (GO:1901072)2.30795453
114metallo-sulfur cluster assembly (GO:0031163)2.30313250
115iron-sulfur cluster assembly (GO:0016226)2.30313250
116cytidine metabolic process (GO:0046087)2.29729336
117cytidine catabolic process (GO:0006216)2.29729336
118cytidine deamination (GO:0009972)2.29729336
119negative regulation of microtubule polymerization (GO:0031115)2.29526288
120cellular copper ion homeostasis (GO:0006878)2.29331817
121regulation of insulin secretion involved in cellular response to glucose stimulus (GO:0061178)2.28442847
122negative regulation of execution phase of apoptosis (GO:1900118)2.28378474
123regulation of B cell apoptotic process (GO:0002902)2.28112534
124positive regulation of TOR signaling (GO:0032008)2.28085417
125hydrogen peroxide metabolic process (GO:0042743)2.28013212
126cellular response to nicotine (GO:0071316)2.27704855
127C-terminal protein amino acid modification (GO:0018410)2.26965457
128protein localization to cilium (GO:0061512)2.26911922
129glutathione biosynthetic process (GO:0006750)2.26687336
130respiratory chain complex IV assembly (GO:0008535)2.25519940
131positive regulation of calcium ion import (GO:0090280)2.25194757
132synaptic vesicle transport (GO:0048489)2.23611860
133establishment of synaptic vesicle localization (GO:0097480)2.23611860
134regulation of vacuole organization (GO:0044088)2.23177255
135adaptation of signaling pathway (GO:0023058)2.22772913
136endosome to pigment granule transport (GO:0043485)2.22505306
137endosome to melanosome transport (GO:0035646)2.22505306
138regulation of voltage-gated calcium channel activity (GO:1901385)2.22105894
139positive regulation of mast cell activation (GO:0033005)2.21927724
140ER overload response (GO:0006983)2.21237381
141negative regulation of interleukin-12 production (GO:0032695)2.21015059
142dopamine metabolic process (GO:0042417)2.20911850
143positive regulation of synaptic transmission, GABAergic (GO:0032230)2.20342865
144negative regulation of glycoprotein metabolic process (GO:1903019)2.19950934
145adult walking behavior (GO:0007628)2.19713250
146intracellular pH reduction (GO:0051452)2.19572428
147mannosylation (GO:0097502)2.19293693
148regulation of type B pancreatic cell apoptotic process (GO:2000674)2.17458961
149purine nucleotide salvage (GO:0032261)2.17016981
150ribonucleoside triphosphate biosynthetic process (GO:0009201)2.16938408
151positive regulation of synaptic transmission, dopaminergic (GO:0032226)2.16307910
152vocalization behavior (GO:0071625)2.15459822
153cellular iron ion homeostasis (GO:0006879)2.14872008
154antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G2.14616364
155pH reduction (GO:0045851)2.14466211
156regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway (GO:19022352.14350858
157lytic vacuole organization (GO:0080171)2.14233739
158lysosome organization (GO:0007040)2.14233739
159protein localization to synapse (GO:0035418)2.14168952
160behavioral response to cocaine (GO:0048148)2.13849799
161cellular response to interferon-beta (GO:0035458)2.13811324
162aggressive behavior (GO:0002118)2.12779841

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1IRF8_22096565_ChIP-ChIP_GC-B_Human3.42463079
2EZH2_22144423_ChIP-Seq_EOC_Human3.38203843
3IRF8_21731497_ChIP-ChIP_J774_Mouse2.88713453
4GBX2_23144817_ChIP-Seq_PC3_Human2.76528842
5TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse2.73876068
6SUZ12_18692474_ChIP-Seq_MESCs_Mouse2.72196023
7SUZ12_18555785_ChIP-Seq_MESCs_Mouse2.55192071
8* FLI1_20887958_ChIP-Seq_HPC-7_Mouse2.29735241
9JARID2_20075857_ChIP-Seq_MESCs_Mouse2.29103169
10SUZ12_18692474_ChIP-Seq_MEFs_Mouse2.28483554
11SUZ12_20075857_ChIP-Seq_MESCs_Mouse2.25937365
12JARID2_20064375_ChIP-Seq_MESCs_Mouse2.22573594
13SUZ12_18974828_ChIP-Seq_MESCs_Mouse2.20550528
14PDX1_19855005_ChIP-ChIP_MIN6_Mouse2.14658795
15NOTCH1_17114293_ChIP-ChIP_T-ALL_Human2.12476602
16MTF2_20144788_ChIP-Seq_MESCs_Mouse2.11841676
17REST_21632747_ChIP-Seq_MESCs_Mouse2.04819575
18RUNX1_20887958_ChIP-Seq_HPC-7_Mouse2.03547407
19ELF1_17652178_ChIP-ChIP_JURKAT_Human2.02395634
20SUZ12_16625203_ChIP-ChIP_MESCs_Mouse2.01811620
21IKZF1_21737484_ChIP-ChIP_HCT116_Human1.99179797
22EZH2_27304074_Chip-Seq_ESCs_Mouse1.97887415
23SUZ12_27294783_Chip-Seq_ESCs_Mouse1.95863358
24VDR_22108803_ChIP-Seq_LS180_Human1.95398516
25NR4A2_19515692_ChIP-ChIP_MN9D_Mouse1.94965137
26EZH2_18974828_ChIP-Seq_MESCs_Mouse1.93369264
27RNF2_18974828_ChIP-Seq_MESCs_Mouse1.93369264
28TAF15_26573619_Chip-Seq_HEK293_Human1.92759780
29EZH2_27294783_Chip-Seq_ESCs_Mouse1.89387160
30EST1_17652178_ChIP-ChIP_JURKAT_Human1.87610799
31BMI1_23680149_ChIP-Seq_NPCS_Mouse1.87111419
32REST_18959480_ChIP-ChIP_MESCs_Mouse1.86272715
33EED_16625203_ChIP-ChIP_MESCs_Mouse1.85456067
34SOX9_22984422_ChIP-ChIP_TESTIS_Rat1.82397010
35ESRRB_18555785_ChIP-Seq_MESCs_Mouse1.77913393
36ETS1_20019798_ChIP-Seq_JURKAT_Human1.76837572
37MEIS1_20887958_ChIP-Seq_HPC-7_Mouse1.73957879
38IRF8_22096565_ChIP-ChIP_GC-B_Mouse1.73922446
39CEBPB_23403033_ChIP-Seq_LIVER_Mouse1.73762977
40BCL6_27268052_Chip-Seq_Bcells_Human1.71379551
41ELF1_20517297_ChIP-Seq_JURKAT_Human1.71331699
42LMO2_20887958_ChIP-Seq_HPC-7_Mouse1.70588367
43NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human1.70062631
44TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat1.68520106
45CEBPA_23403033_ChIP-Seq_LIVER_Mouse1.63601742
46CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons1.63546797
47ZFP57_27257070_Chip-Seq_ESCs_Mouse1.58476713
48SPI1_22096565_ChIP-ChIP_GC-B_Mouse1.55484280
49EBNA2_21746931_ChIP-Seq_IB4-LCL_Human1.52024158
50CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human1.49163706
51MECOM_23826213_ChIP-Seq_KASUMI_Mouse1.48274933
52STAT1_20625510_ChIP-Seq_HELA_Human1.46919204
53GATA2_20887958_ChIP-Seq_HPC-7_Mouse1.45621693
54IRF8_27001747_Chip-Seq_BMDM_Mouse1.44691713
55CTBP2_25329375_ChIP-Seq_LNCAP_Human1.43933974
56E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse1.42651928
57NR3C1_23031785_ChIP-Seq_PC12_Mouse1.41067355
58BCOR_27268052_Chip-Seq_Bcells_Human1.40609198
59SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse1.40443948
60PHC1_16625203_ChIP-ChIP_MESCs_Mouse1.39531732
61SPI1_23547873_ChIP-Seq_NB4_Human1.38651580
62GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.35956640
63MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human1.35309301
64IRF1_21803131_ChIP-Seq_MONOCYTES_Human1.34907889
65RNF2_27304074_Chip-Seq_ESCs_Mouse1.33225571
66SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.30918934
67CTBP1_25329375_ChIP-Seq_LNCAP_Human1.30698485
68* VDR_23849224_ChIP-Seq_CD4+_Human1.28623900
69CTCF_26484167_Chip-Seq_Bcells_Mouse1.27431841
70RBPJ_21746931_ChIP-Seq_IB4-LCL_Human1.22311584
71TAF2_19829295_ChIP-Seq_ESCs_Human1.22289604
72YY1_22570637_ChIP-Seq_MALME-3M_Human1.22277819
73PPARG_19300518_ChIP-PET_3T3-L1_Mouse1.21623541
74STAT4_19710469_ChIP-ChIP_TH1__Mouse1.21257401
75SOX9_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse1.20773725
76SPI1_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse1.20404259
77GABP_17652178_ChIP-ChIP_JURKAT_Human1.20053787
78P300_19829295_ChIP-Seq_ESCs_Human1.19459027
79BMI1_19503595_ChIP-Seq_MEFsC_Mouse1.18938877
80CRX_20693478_ChIP-Seq_ADULT_RETINA_Mouse1.18159227
81RARB_27405468_Chip-Seq_BRAIN_Mouse1.16195997
82* TFEB_21752829_ChIP-Seq_HELA_Human1.15943200
83P300_27268052_Chip-Seq_Bcells_Human1.14420535
84LYL1_20887958_ChIP-Seq_HPC-7_Mouse1.13008298
85SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse1.12551420
86E2F1_20622854_ChIP-Seq_HELA_Human1.12283434
87ERG_21242973_ChIP-ChIP_JURKAT_Human1.11880269
88TET1_21451524_ChIP-Seq_MESCs_Mouse1.11711159
89SIN3A_21632747_ChIP-Seq_MESCs_Mouse1.11664736
90CEBPB_24764292_ChIP-Seq_MC3T3_Mouse1.11509003
91HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human1.11489272
92ETV2_25802403_ChIP-Seq_MESCs_Mouse1.09858077
93LXR_22292898_ChIP-Seq_THP-1_Human1.09448687
94FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse1.09365326
95HOXB4_20404135_ChIP-ChIP_EML_Mouse1.07725026
96CDX2_19796622_ChIP-Seq_MESCs_Mouse1.07632967
97* SFPI1_20887958_ChIP-Seq_HPC-7_Mouse1.07496050
98NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse1.07292161
99OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.06675684
100DROSHA_22980978_ChIP-Seq_HELA_Human1.05998004
101STAT6_20620947_ChIP-Seq_CD4_POS_T_Human1.05648911
102* JARID1A_20064375_ChIP-Seq_MESCs_Mouse1.05101795
103BP1_19119308_ChIP-ChIP_Hs578T_Human1.05015519
104SA1_27219007_Chip-Seq_Bcells_Human1.04439121
105* CEBPB_20513432_ChIP-Seq_MACROPHAGES_Mouse1.03917291
106YY1_21170310_ChIP-Seq_MESCs_Mouse1.03595860
107* CEBPB_20176806_ChIP-Seq_MACROPHAGES_Mouse1.03478361
108NANOG_20526341_ChIP-Seq_ESCs_Human1.03311817
109TOP2B_26459242_ChIP-Seq_MCF-7_Human1.02649981
110* SRY_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse1.02547646
111FOXP2_21765815_ChIP-ChIP_NEURO2A_Mouse1.02014610
112* FLI1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human1.01719988
113ERA_21632823_ChIP-Seq_H3396_Human1.01163351
114KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human1.00869529
115GATA3_21878914_ChIP-Seq_MCF-7_Human1.00852533
116IGF1R_20145208_ChIP-Seq_DFB_Human1.00762317
117ATF3_23680149_ChIP-Seq_GBM1-GSC_Human1.00589316
118* SPI1_23127762_ChIP-Seq_K562_Human1.00301690
119PBX_27287812_Chip-Seq_EMBYONIC-LIMB_Mouse0.99776954
120PHF8_20622854_ChIP-Seq_HELA_Human0.98284113
121TP53_22573176_ChIP-Seq_HFKS_Human0.98154434
122P68_20966046_ChIP-Seq_HELA_Human0.98033218
123THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse0.97935830
124SMAD4_21799915_ChIP-Seq_A2780_Human0.97711283
125PIAS1_25552417_ChIP-Seq_VCAP_Human0.97355847
126ESR1_17901129_ChIP-ChIP_LIVER_Mouse0.97211448
127MYC_19829295_ChIP-Seq_ESCs_Human0.97137168
128LDB1_21186366_ChIP-Seq_BM-HSCs_Mouse0.96982201
129PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human0.96551076
130GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse0.96384675
131* GABP_19822575_ChIP-Seq_HepG2_Human0.95934347
132SMAD2/3_21741376_ChIP-Seq_ESCs_Human0.95753465
133PU.1_20176806_ChIP-Seq_MACROPHAGES_Mouse0.94067124
134CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human0.93595044
135ER_23166858_ChIP-Seq_MCF-7_Human0.93304224
136* FOXP3_21729870_ChIP-Seq_TREG_Human0.92934835
137EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human0.92068947
138TAL1_20887958_ChIP-Seq_HPC-7_Mouse0.91922621
139E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human0.90714668
140RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human0.90537107
141BCL3_23251550_ChIP-Seq_MUSCLE_Mouse0.90519431
142NANOG_19829295_ChIP-Seq_ESCs_Human0.88658314
143SOX2_19829295_ChIP-Seq_ESCs_Human0.88658314
144PAX6_23342162_ChIP-ChIP_BETA-FORBRAIN-LENS_Mouse0.87679748
145SRF_21415370_ChIP-Seq_HL-1_Mouse0.87599974
146* OLIG2_26023283_ChIP-Seq_AINV15_Mouse0.87392193
147CTCF_18555785_ChIP-Seq_MESCs_Mouse0.87016318
148ZNF274_21170338_ChIP-Seq_K562_Hela0.86868296
149NFE2L2_20460467_ChIP-Seq_MEFs_Mouse0.86489198
150NRF2_20460467_ChIP-Seq_MEFs_Mouse0.86489198
151DNAJC2_21179169_ChIP-ChIP_NT2_Human0.86327116
152RNF2_27304074_Chip-Seq_NSC_Mouse0.86220582
153RAD21_21589869_ChIP-Seq_MESCs_Mouse0.85387161
154CBX2_27304074_Chip-Seq_ESCs_Mouse0.85095795
155CTCF_27219007_Chip-Seq_Bcells_Human0.84770375
156SIN3B_21632747_ChIP-Seq_MESCs_Mouse0.83173405
157PBX1_22567123_ChIP-ChIP_OVCAR3_Human0.81392365
158SRY_22984422_ChIP-ChIP_TESTIS_Rat0.79053350
159POU3F2_20337985_ChIP-ChIP_501MEL_Human0.78690112
160GLI1_17442700_ChIP-ChIP_MESCs_Mouse0.77954704
161JUN_21703547_ChIP-Seq_K562_Human0.77618271
162THAP11_20581084_ChIP-Seq_MESCs_Mouse0.77560455
163CTCF_20526341_ChIP-Seq_ESCs_Human0.76840303
164NCOR_22424771_ChIP-Seq_293T_Human0.76830556
165PRDM14_20953172_ChIP-Seq_ESCs_Human0.75878143
166TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human0.75697267
167HTT_18923047_ChIP-ChIP_STHdh_Human0.75354749
168EOMES_21245162_ChIP-Seq_HESCs_Human0.75327539
169TAL1_26923725_Chip-Seq_HPCs_Mouse0.74851944
170TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.74669989
171RCOR3_21632747_ChIP-Seq_MESCs_Mouse0.74148196
172OCT4_20526341_ChIP-Seq_ESCs_Human0.73297257

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0003880_abnormal_central_pattern3.71429219
2MP0004270_analgesia3.18713857
3MP0004859_abnormal_synaptic_plasticity3.14612531
4MP0001529_abnormal_vocalization3.04976815
5MP0002735_abnormal_chemical_nociception2.97244963
6MP0006276_abnormal_autonomic_nervous2.81997446
7MP0002736_abnormal_nociception_after2.80077384
8MP0001968_abnormal_touch/_nociception2.78729639
9MP0001905_abnormal_dopamine_level2.72898329
10MP0002733_abnormal_thermal_nociception2.69276541
11MP0002064_seizures2.63284153
12MP0002734_abnormal_mechanical_nocicepti2.54378568
13MP0001970_abnormal_pain_threshold2.53977297
14MP0003635_abnormal_synaptic_transmissio2.37891377
15MP0009745_abnormal_behavioral_response2.35985899
16MP0003806_abnormal_nucleotide_metabolis2.34286613
17MP0002272_abnormal_nervous_system2.28772182
18MP0009046_muscle_twitch2.27190061
19MP0005671_abnormal_response_to2.22626587
20MP0009785_altered_susceptibility_to2.22607331
21MP0001835_abnormal_antigen_presentation2.21761214
22MP0003724_increased_susceptibility_to2.18109261
23MP0009840_abnormal_foam_cell2.08849275
24MP0010386_abnormal_urinary_bladder2.05116405
25MP0002572_abnormal_emotion/affect_behav2.04386072
26MP0003436_decreased_susceptibility_to2.00689145
27MP0003183_abnormal_peptide_metabolism2.00260772
28MP0002139_abnormal_hepatobiliary_system1.98412827
29MP0005464_abnormal_platelet_physiology1.94974393
30MP0002822_catalepsy1.93799509
31MP0001501_abnormal_sleep_pattern1.92931994
32MP0002837_dystrophic_cardiac_calcinosis1.92924198
33MP0004510_myositis1.92701542
34MP0001440_abnormal_grooming_behavior1.89536755
35MP0000920_abnormal_myelination1.88957842
36MP0003075_altered_response_to1.88569568
37MP0004043_abnormal_pH_regulation1.83590995
38MP0004142_abnormal_muscle_tone1.82172925
39MP0002063_abnormal_learning/memory/cond1.81101228
40MP0001790_abnormal_immune_system1.80259169
41MP0005387_immune_system_phenotype1.80259169
42MP0003329_amyloid_beta_deposits1.74833436
43MP0003011_delayed_dark_adaptation1.73626643
44MP0005025_abnormal_response_to1.68337113
45MP0005000_abnormal_immune_tolerance1.67515065
46MP0001984_abnormal_olfaction1.66621613
47MP0002419_abnormal_innate_immunity1.65612162
48MP0003195_calcinosis1.62302969
49MP0002067_abnormal_sensory_capabilities1.61247533
50MP0005058_abnormal_lysosome_morphology1.60844825
51MP0001986_abnormal_taste_sensitivity1.59784217
52MP0000343_altered_response_to1.58821755
53MP0003122_maternal_imprinting1.57896412
54MP0002909_abnormal_adrenal_gland1.57554225
55MP0002277_abnormal_respiratory_mucosa1.56207964
56MP0001486_abnormal_startle_reflex1.55583425
57MP0003303_peritoneal_inflammation1.54729058
58MP0005645_abnormal_hypothalamus_physiol1.52992855
59MP0000013_abnormal_adipose_tissue1.51023344
60MP0003879_abnormal_hair_cell1.47441493
61MP0002254_reproductive_system_inflammat1.46271568
62MP0002184_abnormal_innervation1.44354246
63MP0000685_abnormal_immune_system1.43968482
64MP0005379_endocrine/exocrine_gland_phen1.43796329
65MP0002723_abnormal_immune_serum1.40272671
66MP0005365_abnormal_bile_salt1.38925760
67MP0001502_abnormal_circadian_rhythm1.38416071
68MP0004924_abnormal_behavior1.37023257
69MP0005386_behavior/neurological_phenoty1.37023257
70MP0005075_abnormal_melanosome_morpholog1.36251948
71MP0008469_abnormal_protein_level1.35241928
72MP0009333_abnormal_splenocyte_physiolog1.34448620
73MP0001756_abnormal_urination1.34057532
74MP0005332_abnormal_amino_acid1.31579021
75MP0002638_abnormal_pupillary_reflex1.31460689
76MP0005535_abnormal_body_temperature1.30563283
77MP0004858_abnormal_nervous_system1.30366356
78MP0001845_abnormal_inflammatory_respons1.30037861
79MP0001533_abnormal_skeleton_physiology1.28629899
80MP0004019_abnormal_vitamin_homeostasis1.27373742
81MP0003634_abnormal_glial_cell1.26776110
82MP0002229_neurodegeneration1.25816132
83MP0001944_abnormal_pancreas_morphology1.25809600
84MP0005646_abnormal_pituitary_gland1.25277216
85MP0002452_abnormal_antigen_presenting1.24422774
86MP0002876_abnormal_thyroid_physiology1.24418056
87MP0009764_decreased_sensitivity_to1.22758838
88MP0004742_abnormal_vestibular_system1.21791636
89MP0003787_abnormal_imprinting1.21218910
90MP0010329_abnormal_lipoprotein_level1.20590933
91MP0005171_absent_coat_pigmentation1.19316803
92MP0006036_abnormal_mitochondrial_physio1.17192971
93MP0005423_abnormal_somatic_nervous1.16837824
94MP0002420_abnormal_adaptive_immunity1.16545509
95MP0001819_abnormal_immune_cell1.15447789
96MP0000955_abnormal_spinal_cord1.14433214
97MP0003172_abnormal_lysosome_physiology1.13680280
98MP0001800_abnormal_humoral_immune1.13541861
99MP0002066_abnormal_motor_capabilities/c1.13177426
100MP0002557_abnormal_social/conspecific_i1.11611407
101MP0008569_lethality_at_weaning1.08082471
102MP0005166_decreased_susceptibility_to1.07020780
103MP0004811_abnormal_neuron_physiology1.06178886
104MP0006082_CNS_inflammation1.06118968
105MP0002078_abnormal_glucose_homeostasis1.05760947
106MP0008004_abnormal_stomach_pH1.04470173
107MP0002653_abnormal_ependyma_morphology1.04138031
108MP0000015_abnormal_ear_pigmentation1.04044339
109MP0003633_abnormal_nervous_system1.02291252
110MP0002882_abnormal_neuron_morphology1.02252572
111MP0001664_abnormal_digestion1.01822681
112MP0005167_abnormal_blood-brain_barrier1.00032370
113MP0002693_abnormal_pancreas_physiology0.98382588
114MP0001764_abnormal_homeostasis0.97588773
115MP0000604_amyloidosis0.95563076
116MP0002405_respiratory_system_inflammati0.95492096
117MP0005084_abnormal_gallbladder_morpholo0.95131038
118MP0009780_abnormal_chondrocyte_physiolo0.94882806
119MP0003191_abnormal_cellular_cholesterol0.94723828
120MP0005448_abnormal_energy_balance0.93623273
121MP0005636_abnormal_mineral_homeostasis0.93498605
122MP0002090_abnormal_vision0.92341569
123MP0009643_abnormal_urine_homeostasis0.91960539
124MP0002751_abnormal_autonomic_nervous0.91526838
125MP0002295_abnormal_pulmonary_circulatio0.90721048
126MP0000778_abnormal_nervous_system0.90624153
127MP0008260_abnormal_autophagy0.89447706
128MP0004145_abnormal_muscle_electrophysio0.88884496
129MP0004885_abnormal_endolymph0.87349441
130MP0005319_abnormal_enzyme/_coenzyme0.87245279
131MP0000372_irregular_coat_pigmentation0.87182481
132MP0001188_hyperpigmentation0.86462666
133MP0006054_spinal_hemorrhage0.86434039
134MP0008875_abnormal_xenobiotic_pharmacok0.85209169
135MP0003631_nervous_system_phenotype0.85163135
136MP0003690_abnormal_glial_cell0.84913187
137MP0003186_abnormal_redox_activity0.84617592
138MP0001963_abnormal_hearing_physiology0.83481701
139MP0002118_abnormal_lipid_homeostasis0.81529202
140MP0002163_abnormal_gland_morphology0.81464421
141MP0005174_abnormal_tail_pigmentation0.79394968
142MP0002138_abnormal_hepatobiliary_system0.79184891
143MP0000230_abnormal_systemic_arterial0.78956757
144MP0006072_abnormal_retinal_apoptosis0.78917276
145MP0001853_heart_inflammation0.78849398
146MP0001765_abnormal_ion_homeostasis0.78085822
147MP0002069_abnormal_eating/drinking_beha0.76235763
148MP0005584_abnormal_enzyme/coenzyme_acti0.76191782
149MP0001542_abnormal_bone_strength0.74099080
150MP0000538_abnormal_urinary_bladder0.73821404
151MP0009642_abnormal_blood_homeostasis0.72838806
152MP0005551_abnormal_eye_electrophysiolog0.72773161
153MP0003638_abnormal_response/metabolism_0.72330551
154MP0008872_abnormal_physiological_respon0.71701855
155MP0005310_abnormal_salivary_gland0.71573705
156MP0008874_decreased_physiological_sensi0.70735525
157MP0003656_abnormal_erythrocyte_physiolo0.70725600
158MP0002752_abnormal_somatic_nervous0.70614950
159MP0000681_abnormal_thyroid_gland0.69320240
160MP0002148_abnormal_hypersensitivity_rea0.69009254
161MP0000749_muscle_degeneration0.68881012
162MP0002332_abnormal_exercise_endurance0.66926642

Predicted human phenotypes

RankGene SetZ-score
1Myokymia (HP:0002411)5.57238323
2Acute necrotizing encephalopathy (HP:0006965)5.16812175
3Abnormal mitochondria in muscle tissue (HP:0008316)4.65388409
4Mitochondrial inheritance (HP:0001427)4.44716566
5Pheochromocytoma (HP:0002666)4.42012634
6Neuroendocrine neoplasm (HP:0100634)4.31332047
7Acute encephalopathy (HP:0006846)4.22919799
8Progressive macrocephaly (HP:0004481)4.20547529
9Hepatocellular necrosis (HP:0001404)3.72647564
10Hypothermia (HP:0002045)3.64118524
11Limb dystonia (HP:0002451)3.61926970
12Petechiae (HP:0000967)3.56999092
13Increased CSF lactate (HP:0002490)3.55993242
14Focal motor seizures (HP:0011153)3.31239757
15Hepatic necrosis (HP:0002605)3.23004904
16Stomatitis (HP:0010280)3.17579691
17Abnormality of macrophages (HP:0004311)3.13978651
18Congenital malformation of the right heart (HP:0011723)3.10376340
19Double outlet right ventricle (HP:0001719)3.10376340
20Renal Fanconi syndrome (HP:0001994)3.06242534
21Increased hepatocellular lipid droplets (HP:0006565)2.97364135
22Prolonged neonatal jaundice (HP:0006579)2.94659809
23Atonic seizures (HP:0010819)2.91103408
24Leukodystrophy (HP:0002415)2.87201973
25Recurrent bacterial skin infections (HP:0005406)2.83021941
26Respiratory failure (HP:0002878)2.72772776
27Purpura (HP:0000979)2.72207834
28Lipid accumulation in hepatocytes (HP:0006561)2.70234665
293-Methylglutaconic aciduria (HP:0003535)2.69137474
30Vacuolated lymphocytes (HP:0001922)2.69112034
31Visual hallucinations (HP:0002367)2.67012624
32Abnormality of mucopolysaccharide metabolism (HP:0011020)2.66222637
33Abnormality of polysaccharide metabolism (HP:0011012)2.66222637
34Abnormality of glycosaminoglycan metabolism (HP:0004371)2.66222637
35Cerebral edema (HP:0002181)2.66101118
36Neurofibrillary tangles (HP:0002185)2.64774090
37Optic disc pallor (HP:0000543)2.64083625
38Recurrent abscess formation (HP:0002722)2.63537318
39Sensory axonal neuropathy (HP:0003390)2.62104989
40Loss of speech (HP:0002371)2.60226728
41Congenital nonbullous ichthyosiform erythroderma (HP:0007479)2.54745326
42Epileptic encephalopathy (HP:0200134)2.53819737
43Increased cerebral lipofuscin (HP:0011813)2.53390511
44Abnormal hair whorl (HP:0010721)2.47724584
45Supranuclear gaze palsy (HP:0000605)2.46713416
46Elevated erythrocyte sedimentation rate (HP:0003565)2.46209044
47Lactic acidosis (HP:0003128)2.43360226
48Decreased activity of mitochondrial respiratory chain (HP:0008972)2.42420234
49Abnormal activity of mitochondrial respiratory chain (HP:0011922)2.42420234
50Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688)2.41828328
51Episodic fever (HP:0001954)2.40096786
52Increased intramyocellular lipid droplets (HP:0012240)2.38834137
53Dysostosis multiplex (HP:0000943)2.38583153
54Retinal dysplasia (HP:0007973)2.36385759
55Nuclear cataract (HP:0100018)2.36093900
56Myotonia (HP:0002486)2.36023628
57Cerebral hemorrhage (HP:0001342)2.33025781
58Urinary glycosaminoglycan excretion (HP:0003541)2.32241590
59Mucopolysacchariduria (HP:0008155)2.32241590
60Chronic obstructive pulmonary disease (HP:0006510)2.32203762
61Obstructive lung disease (HP:0006536)2.32203762
62Absence seizures (HP:0002121)2.32129194
63Generalized aminoaciduria (HP:0002909)2.31823165
64Mutism (HP:0002300)2.31146226
65Dialeptic seizures (HP:0011146)2.30583896
66Muscle abnormality related to mitochondrial dysfunction (HP:0003800)2.29142596
67Anxiety (HP:0000739)2.28433133
68Agitation (HP:0000713)2.27839179
69Focal seizures (HP:0007359)2.27265861
70Abnormal pupillary function (HP:0007686)2.27142186
71Polyphagia (HP:0002591)2.25249877
72Abnormality of renal resorption (HP:0011038)2.25159714
73Exercise intolerance (HP:0003546)2.25156484
74Increased CSF protein (HP:0002922)2.23091978
75Intracellular accumulation of autofluorescent lipopigment storage material (HP:0003204)2.22868571
76Failure to thrive in infancy (HP:0001531)2.20849462
77Parakeratosis (HP:0001036)2.18966959
78Methylmalonic aciduria (HP:0012120)2.17267852
79Abnormality of glycolipid metabolism (HP:0010969)2.14704500
80Abnormality of liposaccharide metabolism (HP:0010968)2.14704500
81Abnormality of glycosphingolipid metabolism (HP:0004343)2.14704500
82Cerebral hypomyelination (HP:0006808)2.13209208
83Ketoacidosis (HP:0001993)2.12021968
84Generalized tonic-clonic seizures (HP:0002069)2.09298030
85Poor suck (HP:0002033)2.08459667
86Systemic lupus erythematosus (HP:0002725)2.06822319
87Delusions (HP:0000746)2.04841001
88Abnormality of aromatic amino acid family metabolism (HP:0004338)2.04559898
89Progressive neurologic deterioration (HP:0002344)2.03664373
90Increased muscle lipid content (HP:0009058)2.03332446
91Severe visual impairment (HP:0001141)2.01877268
92Hypokinesia (HP:0002375)2.01674068
93Hyperparathyroidism (HP:0000843)2.01130631
94Dysautonomia (HP:0002459)2.01002792
95X-linked dominant inheritance (HP:0001423)2.00802741
96Emotional lability (HP:0000712)2.00519363
97Febrile seizures (HP:0002373)2.00323865
98Exertional dyspnea (HP:0002875)1.99582227
99Glycosuria (HP:0003076)1.99120877
100Abnormality of urine glucose concentration (HP:0011016)1.99120877
101Hyperthyroidism (HP:0000836)1.99012082
102Abnormality of calcium-phosphate metabolism (HP:0100530)1.98419408
103Myositis (HP:0100614)1.97611663
104Abnormal eating behavior (HP:0100738)1.97493027
105Hypercortisolism (HP:0001578)1.95555632
106Abnormal autonomic nervous system physiology (HP:0012332)1.94697586
107Cerebral inclusion bodies (HP:0100314)1.93084625
108Abnormality of dicarboxylic acid metabolism (HP:0010995)1.90686550
109Dicarboxylic aciduria (HP:0003215)1.90686550
110Abnormality of magnesium homeostasis (HP:0004921)1.90508085
111Axonal loss (HP:0003447)1.88766845
112Hyperphosphaturia (HP:0003109)1.88668760
113Gait imbalance (HP:0002141)1.88461114
114Recurrent skin infections (HP:0001581)1.87634370
115Prolonged bleeding time (HP:0003010)1.87336886
116Neoplasm of the peripheral nervous system (HP:0100007)1.86714523
117Increased serum lactate (HP:0002151)1.85063782
118Medial flaring of the eyebrow (HP:0010747)1.83275245
119Large for gestational age (HP:0001520)1.83218911
120Poor speech (HP:0002465)1.82973849
121Oligomenorrhea (HP:0000876)1.82061042
122Cardiomegaly (HP:0001640)1.81945955
123Albinism (HP:0001022)1.81230217
124Vaginal atresia (HP:0000148)1.80475956
125Increased neuronal autofluorescent lipopigment (HP:0002074)1.80050286
126Primitive reflexes (palmomental, snout, glabellar) (HP:0002476)1.79899232
127Psychosis (HP:0000709)1.79661239
128Dysmetria (HP:0001310)1.79201680
129Ketosis (HP:0001946)1.79108392
130Congenital ichthyosiform erythroderma (HP:0007431)1.79100181
131Hepatosplenomegaly (HP:0001433)1.78893985
132Congenital primary aphakia (HP:0007707)1.77986919
133Progressive cerebellar ataxia (HP:0002073)1.77597273
134CNS demyelination (HP:0007305)1.76431258
135Genital tract atresia (HP:0001827)1.74753060
136Orchitis (HP:0100796)1.74713474
137Amyloidosis (HP:0011034)1.74417540
138Nephrogenic diabetes insipidus (HP:0009806)1.74279126
139Tongue fasciculations (HP:0001308)1.74209132
140Myoclonus (HP:0001336)1.73540759
141Increased serum pyruvate (HP:0003542)1.72784204
142Abnormality of glycolysis (HP:0004366)1.72784204
143Craniofacial dystonia (HP:0012179)1.71003330
144Diminished movement (HP:0002374)1.70752725
145Focal dystonia (HP:0004373)1.70528371
146Lethargy (HP:0001254)1.69719459
147Respiratory difficulties (HP:0002880)1.65370586
148Methylmalonic acidemia (HP:0002912)1.64889889
149Abnormal rod and cone electroretinograms (HP:0008323)1.62380166
150Increased serum ferritin (HP:0003281)1.62229041
151Gingival bleeding (HP:0000225)1.61911723
152Muscle fibrillation (HP:0010546)1.61103189
153Eczematoid dermatitis (HP:0000976)1.60820470
154Bone cyst (HP:0012062)1.59791375
155Decreased electroretinogram (ERG) amplitude (HP:0000654)1.59566667

Predicted kinase interactions (KEA)

RankGene SetZ-score
1ARAF3.72103808
2GRK53.44702782
3MAP3K123.37866899
4VRK23.26663620
5BCKDK2.72691733
6FRK2.39644506
7CASK2.26619356
8WNK42.25442696
9NTRK32.23942522
10LIMK12.20591185
11NME12.12841352
12STK392.12377840
13MAP3K112.11904968
14OXSR12.04877362
15MAPK151.98648405
16MAP4K21.97784019
17PIM21.94152364
18TXK1.86939397
19CDK191.85245852
20IRAK31.76302802
21GRK71.75139471
22NTRK11.73896527
23MAP3K91.73375973
24TNK21.71464406
25MAP2K61.65685693
26WNK31.60723904
27BRAF1.58869455
28CAMKK21.57876518
29NME21.56357567
30MAPKAPK51.54985709
31TAOK11.52645667
32TYK21.46801381
33RIPK41.45611489
34ADRBK21.44269343
35IKBKB1.44197019
36UHMK11.41195527
37TBK11.40994825
38PRPF4B1.38038003
39CAMK2B1.35309318
40SIK31.34936052
41BMPR1B1.34119311
42MAP4K11.32521844
43TESK21.30167901
44GRK11.28664921
45TESK11.26617345
46MAP2K71.26231730
47MAP3K31.26021538
48MYLK1.24344441
49IRAK41.22848896
50MUSK1.21335520
51KDR1.20220087
52KSR21.20200010
53MAP3K21.20021804
54PLK21.18132699
55MINK11.17796116
56BCR1.17201018
57CAMK2D1.14038553
58INSRR1.10050080
59TAOK21.09080988
60CAMK2A1.05210744
61CAMK2G1.03265422
62CSNK1G31.01398638
63DAPK21.00170659
64MAPK130.99052467
65BLK0.98132181
66BMPR20.96650795
67STK160.96632096
68MST40.96154385
69CDK140.94716396
70PTK2B0.92059220
71GRK60.91741476
72PRKCG0.90334910
73PRKD30.89681752
74CSNK1A1L0.89560252
75ZAP700.89245818
76PRKCE0.88995316
77MARK10.88695788
78CDK50.88252844
79ADRBK10.87265527
80IKBKE0.85022447
81SYK0.84403443
82DAPK10.83401470
83TNIK0.83325064
84VRK10.82655319
85AKT30.79251234
86DAPK30.78668375
87CSNK1G20.78167756
88MAP2K30.76299538
89CSK0.75607157
90EPHA40.75123296
91CDK180.74638644
92PNCK0.73941613
93PAK60.73888382
94SGK2230.73679560
95SGK4940.73679560
96ILK0.72891592
97MAP3K40.72403700
98LYN0.71968637
99CDK150.70225682
100PRKG20.70168757
101NUAK10.70000256
102IRAK20.69581447
103PINK10.68578635
104MAP2K40.67885484
105MAP3K10.66861073
106PBK0.65877336
107PRKCI0.65796937
108MAPKAPK30.65020130
109CDK11A0.64555172
110PAK30.63798369
111PHKG10.62486721
112PHKG20.62486721
113WNK10.62146701
114PIK3CG0.61793671
115MAP2K20.58588682
116TGFBR20.57541408
117ABL20.56781695
118MARK30.56657254
119FGR0.56593057
120TLK10.56455478
121ITK0.56053115
122PKN10.55386979
123ERN10.54346090
124EIF2AK30.53153280
125DYRK20.52224477
126MET0.51957755
127PRKACA0.51836982
128LRRK20.51077504
129MATK0.50337624
130PAK10.49859406
131CSNK1G10.49711633
132CSF1R0.49656157
133NTRK20.47259083
134PRKD20.46940942
135MAP2K10.46802925
136KIT0.46247011
137PRKCQ0.45597915
138JAK30.45575879
139BTK0.45157680
140NEK60.45053212
141PDK10.45013207
142TAOK30.44646814
143CAMK10.43255635
144STK110.43213570
145LCK0.43076221
146PDPK10.42751647
147ROCK20.41216639
148TEC0.41053102
149HIPK20.40696823
150FES0.40433095
151IRAK10.39992481
152EPHB10.39553311
153MOS0.39087781
154GSK3A0.35271382

Predicted pathways (KEGG)

RankGene SetZ-score
1Oxidative phosphorylation_Homo sapiens_hsa001905.25358597
2Parkinsons disease_Homo sapiens_hsa050124.19642433
3Collecting duct acid secretion_Homo sapiens_hsa049663.82296512
4Synaptic vesicle cycle_Homo sapiens_hsa047213.28511843
5Alzheimers disease_Homo sapiens_hsa050103.26121359
6Protein export_Homo sapiens_hsa030602.98424679
7Vibrio cholerae infection_Homo sapiens_hsa051102.89440812
8Huntingtons disease_Homo sapiens_hsa050162.63302034
9Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049322.56990558
10Cardiac muscle contraction_Homo sapiens_hsa042602.11082588
11Rheumatoid arthritis_Homo sapiens_hsa053231.97331979
12Allograft rejection_Homo sapiens_hsa053301.70681956
13Vasopressin-regulated water reabsorption_Homo sapiens_hsa049621.68752557
14Proteasome_Homo sapiens_hsa030501.66429418
15Fatty acid elongation_Homo sapiens_hsa000621.64979148
16Sulfur relay system_Homo sapiens_hsa041221.64940803
17Nicotine addiction_Homo sapiens_hsa050331.62759854
18Terpenoid backbone biosynthesis_Homo sapiens_hsa009001.59627980
19Sulfur metabolism_Homo sapiens_hsa009201.59272606
20GABAergic synapse_Homo sapiens_hsa047271.56966126
21SNARE interactions in vesicular transport_Homo sapiens_hsa041301.54838535
22Autoimmune thyroid disease_Homo sapiens_hsa053201.51957240
23Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051201.46061915
24Retrograde endocannabinoid signaling_Homo sapiens_hsa047231.41211221
25Serotonergic synapse_Homo sapiens_hsa047261.38518284
26Phagosome_Homo sapiens_hsa041451.38250842
27Cytosolic DNA-sensing pathway_Homo sapiens_hsa046231.35452385
28Lysosome_Homo sapiens_hsa041421.33913991
29Intestinal immune network for IgA production_Homo sapiens_hsa046721.33132181
30Staphylococcus aureus infection_Homo sapiens_hsa051501.31386989
31Cocaine addiction_Homo sapiens_hsa050301.30785289
32Maturity onset diabetes of the young_Homo sapiens_hsa049501.30097790
33Insulin secretion_Homo sapiens_hsa049111.29298663
34Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049611.26886387
35Taste transduction_Homo sapiens_hsa047421.21290970
36Amphetamine addiction_Homo sapiens_hsa050311.19297783
37Morphine addiction_Homo sapiens_hsa050321.19042663
38Circadian entrainment_Homo sapiens_hsa047131.17898364
39Regulation of autophagy_Homo sapiens_hsa041401.15926958
40Dopaminergic synapse_Homo sapiens_hsa047281.13771715
41Olfactory transduction_Homo sapiens_hsa047401.10902298
42Steroid biosynthesis_Homo sapiens_hsa001001.06540021
43Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005631.06013276
44Taurine and hypotaurine metabolism_Homo sapiens_hsa004301.02240052
45Antigen processing and presentation_Homo sapiens_hsa046120.98783054
46Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.98728505
47Inflammatory bowel disease (IBD)_Homo sapiens_hsa053210.95290375
48Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.95154359
49Glutamatergic synapse_Homo sapiens_hsa047240.94434913
50Leishmaniasis_Homo sapiens_hsa051400.90161762
51Hematopoietic cell lineage_Homo sapiens_hsa046400.89310491
52Cholinergic synapse_Homo sapiens_hsa047250.89085597
53Primary immunodeficiency_Homo sapiens_hsa053400.87397856
54Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.86913441
55Type I diabetes mellitus_Homo sapiens_hsa049400.86473157
56Osteoclast differentiation_Homo sapiens_hsa043800.85978815
57Other glycan degradation_Homo sapiens_hsa005110.85125170
58Sphingolipid metabolism_Homo sapiens_hsa006000.84603753
59Salivary secretion_Homo sapiens_hsa049700.78703022
60Long-term potentiation_Homo sapiens_hsa047200.78474441
61Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.78381883
62Synthesis and degradation of ketone bodies_Homo sapiens_hsa000720.78351838
63Ether lipid metabolism_Homo sapiens_hsa005650.78185232
64Toll-like receptor signaling pathway_Homo sapiens_hsa046200.76295566
65Pancreatic secretion_Homo sapiens_hsa049720.70344873
66Primary bile acid biosynthesis_Homo sapiens_hsa001200.69904531
67Malaria_Homo sapiens_hsa051440.66771074
68Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001300.65056639
69Galactose metabolism_Homo sapiens_hsa000520.64545633
70Valine, leucine and isoleucine degradation_Homo sapiens_hsa002800.64463627
71Long-term depression_Homo sapiens_hsa047300.62253317
72Folate biosynthesis_Homo sapiens_hsa007900.61186806
73Citrate cycle (TCA cycle)_Homo sapiens_hsa000200.61176346
74Vitamin B6 metabolism_Homo sapiens_hsa007500.60636934
75Phototransduction_Homo sapiens_hsa047440.59839431
76Legionellosis_Homo sapiens_hsa051340.59476015
77Cytokine-cytokine receptor interaction_Homo sapiens_hsa040600.59257344
78Mineral absorption_Homo sapiens_hsa049780.57288772
79Metabolic pathways_Homo sapiens_hsa011000.55271960
80Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010400.54699602
81Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.54383377
82Prion diseases_Homo sapiens_hsa050200.53925806
83Calcium signaling pathway_Homo sapiens_hsa040200.52690180
84Asthma_Homo sapiens_hsa053100.52548457
85Tyrosine metabolism_Homo sapiens_hsa003500.51300822
86Gastric acid secretion_Homo sapiens_hsa049710.50782397
87Histidine metabolism_Homo sapiens_hsa003400.49582725
88Pyruvate metabolism_Homo sapiens_hsa006200.47342311
89Tryptophan metabolism_Homo sapiens_hsa003800.47249729
90Ribosome_Homo sapiens_hsa030100.47241821
91RIG-I-like receptor signaling pathway_Homo sapiens_hsa046220.46469496
92Phenylalanine metabolism_Homo sapiens_hsa003600.45953888
93Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047500.44591669
94NOD-like receptor signaling pathway_Homo sapiens_hsa046210.43221189
95Renin secretion_Homo sapiens_hsa049240.42797278
96NF-kappa B signaling pathway_Homo sapiens_hsa040640.42123921
97Aldosterone synthesis and secretion_Homo sapiens_hsa049250.41888617
98Arachidonic acid metabolism_Homo sapiens_hsa005900.41555727
99Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.41329871
100N-Glycan biosynthesis_Homo sapiens_hsa005100.40919285
101Pyrimidine metabolism_Homo sapiens_hsa002400.39896550
102Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.39736195
103Linoleic acid metabolism_Homo sapiens_hsa005910.38296270
104Vascular smooth muscle contraction_Homo sapiens_hsa042700.36974048
105Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049600.36438790
106Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042610.35961088
107Glycosaminoglycan degradation_Homo sapiens_hsa005310.35611912
108beta-Alanine metabolism_Homo sapiens_hsa004100.35573868
109Chemokine signaling pathway_Homo sapiens_hsa040620.34273388
110Shigellosis_Homo sapiens_hsa051310.34133743
111Purine metabolism_Homo sapiens_hsa002300.33387865
112Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046500.32885546
113Gap junction_Homo sapiens_hsa045400.31735031
114Glycerophospholipid metabolism_Homo sapiens_hsa005640.30218962
115RNA polymerase_Homo sapiens_hsa030200.30198053
116Glutathione metabolism_Homo sapiens_hsa004800.30108287
117Graft-versus-host disease_Homo sapiens_hsa053320.29796017
118Chagas disease (American trypanosomiasis)_Homo sapiens_hsa051420.29414336
119Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.29148306
120Endocytosis_Homo sapiens_hsa041440.28552685
121Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.28489546
122Salmonella infection_Homo sapiens_hsa051320.28468765
123Chemical carcinogenesis_Homo sapiens_hsa052040.28465093
124Butanoate metabolism_Homo sapiens_hsa006500.28416047
125Thyroid hormone synthesis_Homo sapiens_hsa049180.28352248
126Nitrogen metabolism_Homo sapiens_hsa009100.27563225
127African trypanosomiasis_Homo sapiens_hsa051430.27519401
128Complement and coagulation cascades_Homo sapiens_hsa046100.27002655
129Pertussis_Homo sapiens_hsa051330.26764334
130Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.26649438
131Oxytocin signaling pathway_Homo sapiens_hsa049210.26485170
132Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.25719310
133Tuberculosis_Homo sapiens_hsa051520.25313835
134alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.24655918
135cAMP signaling pathway_Homo sapiens_hsa040240.23756096
136Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.23139452
137Drug metabolism - cytochrome P450_Homo sapiens_hsa009820.22847340
138Arginine and proline metabolism_Homo sapiens_hsa003300.22663158
139Peroxisome_Homo sapiens_hsa041460.22654484
140Fructose and mannose metabolism_Homo sapiens_hsa000510.22017777
141Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005340.21512981
142Pentose phosphate pathway_Homo sapiens_hsa000300.21122090

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